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Multicellular Living Organisms And Unmodified Parts Thereof And Related Processes > Nonhuman Animal > Transgenic Nonhuman Animal (e.g., Mollusks, Etc.)

Transgenic Nonhuman Animal (e.g., Mollusks, Etc.)

Transgenic Nonhuman Animal (e.g., Mollusks, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

11/22/07 - 20070271621 - Nucleic acids encoding a chimeric glycosyltransferase
The invention relates to nucleic acids which encode glycosyltransferase and are useful in producing cells and organs from one species which may be used for transplantation into a recipient of another species. It also relates to the production of nucleic acids which, when present in cells of a transplanted organ, ...

11/01/07 - 20070256147 - Combinatorial marking of cells and cell structures with reconstituted fluorescent proteins
The present invention relates to the use of split fluorescent proteins to determine whether promoters are coordinately active, whereby the transcriptional expression of incomplete portions of a fluorescent protein is controlled by different promoters and coordinate (not necessarily contemporaneous) promoter activity results in the reconstitution of a fluorescent protein. The ...

08/09/07 - 20070186291 - Method for generating overexpression of alleles in genes of unknown function
Methods for generating and using novel overexpression activity alleles of a gene in any organism, especially Drosophilia, are provided. Such alleles may be utilized in screening assays, and used to generate dominant-negative forms of bacterial toxins. ...

07/19/07 - 20070169209 - Apparatuses and methods for the production of haematophagous organisms and parasites suitable for vaccine production
Disclosed are apparatuses and methods for the production of attenuated aseptic parasites in haematophagous insects generally, and production of Plasmodium species sporozoites in Anopheles species mosquitoes specifically; apparatuses and methods for the production of strains of haematophagous insects with desired properties such as hypoallergenicity or hyperinfectivity; methods of producing a ...

07/19/07 - 20070169208 - Silkworm strains for enabling production of proteins using various baculovirus
The present invention provides a method for producing a recombinant protein, characterized by using an AcNPV-susceptible silkworm and a baculovirus. The silkworm used in the present invention is preferably a silkworm of any one of the following strains i) to iv): i) a silkworm of AcNPV-susceptible strain c11 or a ...

06/28/07 - 20070150970 - Compositions and methods for identifying modulators of transducisomes, a new class of therapeutic targets
The invention provides cells and methods for identifying modulators of signal transduction, based on transducisome proteins that coordinate and assemble many types of signal transduction proteins. A transducisome is a PDZ domain containing protein that binds at least one signal transduction protein or a PDZ domain containing protein with at ...

05/10/07 - 20070107070 - Invertebrate animal model with neurodegenerative phenotype for screening and testing substances
The present invention claims an invertebrate animal that has been modified to express a set of genes, said set comprising the gene coding for a modified version of the gamma subunit of AMP-activated protein kinase (AMPKg). According to the invention, the animal displays an identifiable phenotype related to lipid metabolism ...

03/22/07 - 20070067857 - Therapeutic agent for ngf
This invention relates to the use of a domain of Trk as a therapeutic agent and for screening purposes and rational design of NGF nimetics. ...

03/22/07 - 20070067856 - therapeutic agent for ngf
This invention relates to the use of a domain of Trk as a therapeutic agent and for screening purposes and rational design of NGF mimetics. ...

03/22/07 - 20070067855 - Production of human glycosylated proteins in transgenic insects
This invention relates, e.g., to transgenic insects, or progeny thereof, whose cells contain at least one genomically integrated, expressible, nucleic acid encoding two or more of a set of Nglycosylation enzymes that can glycosylate a heterologous protein with a mammalianized (e.g., humanized) glycosylation pattern. The glycosylation genes are preferably expressed ...

03/08/07 - 20070056051 - Expression system for insect pest control
Promoters active in insects can be enhanced by positive feedback mechanisms and associated with repressible lethal effects. ...

11/30/06 - 20060272039 - Methods of identifying longevity modulators and therapeutic methods of use thereof
The present invention is based at least in part on the discovery of a role for the JNK signaling pathway in longevity. In particular, the present inventors have shown that overexpression of c-jun N-terminal kinase 1 (jnk-1) extends lifespan and that said extended lifespan is associated with DAF-16 phosphorylation by ...

11/23/06 - 20060265766 - Fish and the production thereof
This invention is directed to the composition, method of production, and use of improved edible fish, crustacean, or mollusk products enriched with one or more components that provide health benefits to humans or other animals consuming the product. ...

10/26/06 - 20060242720 - Inducible site-directed mutagenesis through conditional gene rescue
The present invention relates to a conditionally inducible site-directed mutant cell, comprising a mutated allele of a gene; wherein said allele comprises a mutation that was introduced by using a suitable mutagenesis technique, a rescue allele of said mutated gene that can be conditionally inactivated, wherein said mutation in said ...

10/26/06 - 20060242719 - Nucleotide sequences of shrimp beta-actin and actin promoters and their use in gentic transformation technology
The present invention relates to isolated actin and β-actin nucleic acid promoter molecules from shrimp; nucleic acid expression cassettes including actin and β-actin promoter molecules isolated from shrimp; and expression vectors, host cells, and transgenic animals transduced with the isolated actin and β-actin nucleic acid promoter. Also disclosed are methods ...

09/28/06 - 20060218652 - System for gene targeting and producing stable genomic transgene insertions
The novel germ-line transformation systems disclosed in this patent application allow the physical deletion of transposon DNA following the transformation process, and the targeting of transgene integrations into predefined target sites. In this way, transposasemediated mobilization of genes-of-interest are excluded mechanistically and random genomic integrations eliminated. In contrast to conventional ...

09/21/06 - 20060212949 - Stable integrands
There is provided a transposable element comprising at least four inverted repeats, at least two of which are each inverted in relation to another, the element comprising DNA for insertion into a host genome, the DNA being located between two pairs of opposing repeats excisable by a transposase in situ ...

08/31/06 - 20060195917 - Non-mammalian transgenic animal having an adult onset neurodegenerative phenotype
Transgenic non-mammalian animals, e.g. flies, that exhibit an adult onset neurodegenerative phenotype, as well as methods for preparing the same, are provided. Also provided are methods of using the subject transgenic non-mammalian animals to identify compounds having activity with respect to adult onset neurodegenerative diseases. Finally, kits for screening compounds ...

08/10/06 - 20060179497 - Methods to treat conditions associated with insulin signaling dysregulation
The invention discloses a method to identify proteins involved in the insulin signaling pathway. The invention also discloses suitable targets for the development of new therapeutics to treat, prevent or ameliorate pathological conditions associated with dysregulation of the insulin signaling pathway. The invention also relates to methods to treat, prevent ...

07/20/06 - 20060162002 - Eukaryotic genes involved in adult lifespan regulation
The present invention relates to regulation of adult lifespan in eukaryotes. More particularly, the present invention is directed to methods of assaying for genes, gene products, and genes in pathways controlled by such genes and gene products, using RNAi and microarray analysis, that regulate lifespan (e.g., extend or truncate adult ...

07/20/06 - 20060162001 - Mammalian grainyhead transcription factors
The present invention provides mammalian homologs of the Drosophila Grainyhead (GRH) transcription factor, call MGR and means of identifying such proteins and their genes. Nucleic acid and protein sequences are provided for human and mouse MGR transcription factors. In addition mammalian isoforms of MGR including human MGR p49, human p70, ...

06/15/06 - 20060130162 - Shrimp and the production thereof
This invention is directed to compositions comprising improved edible shrimp and other crustaceans. The shrimp or other crustaceans are enriched with one or more components that provide benefits, such as improved taste and/or appearance, or improved health benefits for humans consuming them. The invention also relates to methods of producing ...

03/23/06 - 20060064763 - Unactivated oocytes as cytoplast recipients for nuclear transfer
A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division. The oocyte is not activated at the time of transfer, so that the donor nucleus is kept exposed to the recipient cytoplasm for a ...

02/09/06 - 20060031950 - Non-mammalian transgenic animal model for cellular proliferative diseases
Non-mammalian, transgenic animals, e.g. flies, that exhibit neoplastic phenotypes, i.e. spontaneously produce metastatic tumors, are provided. Also provided are methods of using the subject transgenic non-mammalian animals to identify compounds having activity with respect to cellular proliferative, and particularly neoplastic, diseases. Finally, kits for screening compounds for anti-neoplastic activity are ...

01/26/06 - 20060021070 - Production of chimeric bovine or porcine animals using cultured inner cell mass
Novel cultured inner cell mass (CICM) cells, and cell lines, derived from ungulates, in particular, pigs and cows, and methods for their preparation are provided. The subject CICMs possess similar morphology and express cell markers identically or substantially similarly to ICMs of undifferentiated developing embryos for prolonged culturing periods. Heterologous ...

10/27/05 - 20050241011 - Enclosed aquacultural systems for production of purified recombinant proteins
The invention provides a production method for purified recombinant proteins of commercial value prepared in enclosed aquatic systems. The production system provides biosecure containment of genetically engineered aquatic organisms for an alternative production method for complex proteins requiring post-translational modification that is best done in eukaryotic expression systems. Possible aquatic ...

10/13/05 - 20050229265 - Insect ammunition vectors and methods of use to identify pesticide targets
The present invention provides methods for identifying pesticide targets and pesticidal agents using transposable elements in insects and insect cells lines. The invention provides engineered transposable elements for use in identification of pesticide targets. The invention further provides a biological array, a collection of transgenic insect lines or insect cell ...

09/29/05 - 20050216962 - Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species
A transgenic non-human aquatic organisms, such as piscine, crustacean, mollusks, and the like, having a transgene which results in disrupting the production of and/or activity of growth differentiation factor-8 (GDF-8) chromosomally integrated into the germ cells of the aquatic organism is disclosed. Also disclosed are methods for making such organisms ...

09/08/05 - 20050198697 - Transgenic mollusk and method for producing the same
A transgenic mollusk which can express a desired foreign gene, and a method for producing the same are disclosed. The mollusk is a transgenic mollusk into which a desired foreign gene (excluding a gene giving resistance to a virus) is introduced, which expresses the foreign gene. This transgenic mollusk can ...

07/14/05 - 20050155091 - Prkag3 gene promoter and uses thereof
The invention provides an isolated human Prkag3 promoter. Expression constructs containing the Prkag3 promoter also are provided, as are methods of using such expression constructs to direct expression of a heterologous coding sequence. Host cells containing an expression construct of the invention are provided, as well as methods of using ...

07/07/05 - 20050149997 - Sterilization of marine organisms by manipulation of dna content
A novel method of generating a sterile marine organism is disclosed. The method of generating sterile wild type and transgenic marine organisms having triploid genomes is also disclosed. Specifically, we disclose methods of inducing sterility in a number of fish and other species such that their progeny cannot produce offspring ...



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