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Multicellular Living Organisms And Unmodified Parts Thereof And Related Processes > Nonhuman Animal > The Nonhuman Animal Is A Model For Human Disease > Immunodeficiency Disease

Immunodeficiency Disease

Immunodeficiency Disease patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

07/12/07 - 20070162983 - Diagnostic and therapeutic use of the human sgpl1 gene and protein for neurodegenerative diseases
The present invention discloses the differential expression of a gene coding for SGPL1 in specific brain regions of Alzheimer's disease patients. Based on this finding, the invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease, in a subject, or for determining whether a subject ...

08/10/06 - 20060179496 - Nucleic acid sequences differentially expressed in cancer tissue
This invention relates to novel nucleic acid sequences which are differentially expressed in cancer cells. The invention also relates to proteins and peptides encoded by the sequences, to diagnostic assays and therapeutic agents based on the sequences and proteins, and to probes, antisense constructs, and antibodies derived from the sequences ...

07/27/06 - 20060168670 - Gene families associated with cancers
The invention relates generally to the changes in gene expression in human tissues from cancer patients. The invention relates specifically to human gene families which are differentially expressed in cancer tissues of breast, colon, esophagus, kidney, liver, lung, lymph node, ovary, pancreas, prostate, rectum, and/or stomach compared to corresponding normal ...

06/08/06 - 20060123494 - Reconstituted human breast tumor model
A reconstituted human breast tumor model is disclosed. The model, which is incorporated into mice, provides actual tumors that arise spontaneously, thereby mimicking naturally occurring breast cancer. The tumors are genetically human, because they arise from human mammary tissues that develop from human mammary epithelial cells implanted into host mice. ...

06/08/06 - 20060123493 - Reconstituted human breast tumor model
A reconstituted human breast tumor model is disclosed. The model, which is incorporated into mice, provides actual tumors that arise spontaneously, thereby mimicking naturally occurring breast cancer. The tumors are genetically human, because they arise from human mammary tissues that develop from human mammary epithelial cells implanted into host mice. ...

02/16/06 - 20060037089 - In vivo models for rabgef1-dependent signaling and functions
Non-human transgenic animal models and cells derived therefrom are provided for RabGEF1 function. RabGEF1 is a negative regulator of FcεRI-dependent mast cell activation and T cell activation via the T cell receptor and a lack of RabGEF1 results in the development of skin inflammation in vivo. The mast cells derived ...



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