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Data Processing: Structural Design, Modeling, Simulation, And Emulation > Simulating Nonelectrical Device Or System > Biological Or Biochemical

Biological Or Biochemical

Biological Or Biochemical patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/07/06 - 20060277016 - Biological simulation system and computer program product
With an object to seek parameters of a biological model corresponding to individual patents, the present invention provides a biological simulation system comprises an internal parameter set generating section which generates internal parameter sets constituting a biological model, a biological model computing section computing output of a biological model which ...

12/07/06 - 20060277015 - Simulation system for functions of biological organs and recording medium in which program therefor is recorded
A simulation system for simulating functions of biological organs, comprising a biological model in which the functions of the biological organs are expressed by mathematical models. The biological model comprises a hepatic metabolism model block having specified input and output relating to hepatic function for simulating the hepatic function. The ...

12/07/06 - 20060277014 - Dairy production information system
A method for allocating dairy end product pricing risk in a dairy production system is described. The method includes providing a fixed price for a future period for a dairy end product to a retailer of the dairy end product, determining a cost of production for the dairy end product, ...

11/30/06 - 20060271344 - Language for networks
Presently described is a formal language for describing the function of biochemical networks. Because it is a language, it includes a method of parsing, or understanding the language, which is a highly complex recursive algorithm. This formal language, the Cell Language, is described both informally, so that it may be ...

11/02/06 - 20060247904 - Exoskeleton controller for a human-exoskeleton system
Techniques are provided for controlling an exoskeleton actuator at a joint of a human-exoskeleton system by receiving system parameters for the human-exoskeleton system, receiving generalized coordinates for the human-exoskeleton system, and determining an equivalent joint torque for the exoskeleton actuator to compensate for a selected force. While providing partial or ...

10/26/06 - 20060241926 - Methods, systems, and computer program products for producing theoretical mass spectral fragmentation patterns of chemical structures
Methods, systems, and computer program products for generating theoretical mass spectral fragmentation patterns of a chemical structure is provided. The method includes obtaining a description of a chemical structure and generating, from the description, a list of chemical structure information. A binary tree data structure is used to organize the ...

10/19/06 - 20060235671 - Real-time virtual endoscopy
In a method of real-time 3-D visualization and navigation for interventional procedures a position is determined at which data will be acquired, and data is acquired at the position. Features are extracted from the acquired data. A model described by the extracted features is built or updated, wherein updating the ...

10/19/06 - 20060235670 - Method and system for selecting therapeutic targets using molecular interaction dynamic networks
The present invention concerns the field of integrative analysis of molecular interactions in a biological system. In particular, it pertains to a method for obtaining a dynamic model of a molecular interaction network in a biological system that allows analysis of said interactions when a stimulus is applied to the ...

10/19/06 - 20060235669 - Method and system for 3d blood vessel localization
A method and apparatus are provided for modeling circulation in a living subject. The method includes the steps of developing a model for living subjects in general and correcting the model to substantially conform to the overall cerebral physiology of the living subject. The method further includes the step of ...

10/12/06 - 20060229856 - Systems, devices, and methods for diffusion tractography
Certain exemplary embodiments comprise a method, which can comprise automatically causing a representation of body tissue to be rendered. The body tissue can be tracked via clusters. The clusters each can comprise a predetermined number of particles. Each particle of a particular cluster can be representative of a discreet path ...

10/05/06 - 20060224371 - Information system for metabolic flux analysis using extensible markup language and operating method thereof
The present invention relates to an MFA (Metabolic Flux Analysis) information system using an XML (eXtensible Markup Language) and an operating method thereof. More specifically, the invention relates to an MFA information system and an operating method thereof, which generates, edits, stores and visualizes an MFA model feature and an ...

09/21/06 - 20060212282 - Molecular modeling method and system
A molecular modeling method and system to provide a dielectric function that reflects the plurality of models simultaneously used in molecular modeling. For interactions similar to those used during the development of a charge model, the dielectric is similar to the charge model dielectric. In a second embodiment, an approximation ...

09/07/06 - 20060200330 - Methods and systems for modeling and simulating biochemical pathways
The present invention relates to a method for modeling and simulating a biochemical pathway and a system for the same, more particularly to a method for modeling and simulating a biochemical pathway which comprises: developing a mathematical dynamics model that applies biological data of a signal transduction pathway within a ...

08/31/06 - 20060195308 - Methods and models for cholesterol metabolism
The invention encompasses novel methods for developing a computer model of cholesterol metabolism in an animal. In particular, the models include representations of biological processes associated with both lipid flux and lipoprotein particles. The invention also encompasses computer models of cholesterol metabolism, methods of simulating cholesterol metabolism and computer systems ...

08/24/06 - 20060190226 - Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
The subject invention provides systems and methods that facilitate AIDS vaccine cocktail assembly via machine learning algorithms such as a cost function, a greedy algorithm, an expectation-maximization (EM) algorithm, etc. Such assembly can be utilized to generate vaccine cocktails for species of pathogens that evolve quickly under immune pressure of ...

08/10/06 - 20060178862 - Methods and systems for designing machines including biologically-derived parts
A preferred embodiment of the present invention comprises computer-implemented methods for providing user assistance in biomachine design that, first, retrieve one or more digitally-represented candidate design items stored in a bioengineering knowledge base by translating requirements provided for a biomachine according to a bioengineering domain model into queries to the ...

08/10/06 - 20060178861 - Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
The subject invention provides systems and methods that facilitate AIDS vaccine cocktail assembly via machine learning algorithms such as a cost function, a greedy algorithm, an expectation-maximization (EM) algorithm, etc. Such assembly can be utilized to generate vaccine cocktails for species of pathogens that evolve quickly under immune pressure of ...

08/03/06 - 20060173663 - Methods, system, and computer program products for developing and using predictive models for predicting a plurality of medical outcomes, for evaluating intervention strategies, and for simultaneously validating biomarker causality
Methods, systems, and computer program products for developing and using predictive models for predicting medical outcomes and for evaluating intervention strategies, and for simultaneously validating biomarker causality are disclosed. According to one method, clinical data from different sources for a population of individuals is obtained. The clinical data may include ...

07/27/06 - 20060167670 - Photon-based modeling of the human eye and visual perception
A photon-based model of individual cones in the human eye perceiving images on digital display devices is presented. Playback of streams of pixel video data is modeled as individual photon emission events from within the physical substructure of each display pixel. The generated electromagnetic wavefronts are refracted through a four ...

07/20/06 - 20060161408 - Population pharmacokinetic modeling and analysis (pdx-pop™)
A biological modeling system and method for enhanced computer-aided analysis of biological response data provides information synthesized from multiple sources. An executable model of a biological system is developed from information and structures based on multiple sources. In a preferred embodiment, biological data sets are selected by a user from ...

07/20/06 - 20060161407 - Modeling biological effects of molecules using molecular property models
Method, apparatus, and article of manufacture for modeling the biological effects of a molecule are disclosed. A machine learning application may be configured to process a set of training examples regarding a biological property of interest. Once trained, the machine learning application may be configured to generate a prediction regarding ...

07/13/06 - 20060155520 - Model-based pre-assembly testing of multi-component production devices
A multi-component production devices in accordance with a device design having performance specifications is made by a method comprising receiving respective component behavioral models of the production components constituting the production device; combining the component behavioral models in accordance with the device design to form a device behavioral model; and, ...

07/06/06 - 20060149522 - Image-based computational mechanical analysis and indexing for cardiovascular diseases
A method and a computer system, for providing an assessment for disease status of a disease, such as a cardiovascular disease, employ construction of image-based 3D computational model of an organ representative of the disease status; computationally obtaining a certain mechanical distribution using the 3D-organ model; and computational, quantitative analysis ...

07/06/06 - 20060149521 - Modulating nuclear receptor coactivator binding
The present invention comprises cocrystal of a nuclear receptor comprising a molecule bound to the coactivator binding site of said nuclear receptor. The present invention further comprises a machine-readable data storage medium encoded with machine readable data corresponding to the structure coordinates of amino acids of a nuclear receptor coactivator ...

06/29/06 - 20060142986 - System method for simulating conciousness
A simulated consciousness method (10) for an improved human/computer interface. A computer system (12) is programmed to have a Digital Life Form (32) possessing a plurality of attributes (65). A plurality of actions (64) taken relative to objects (60) in the environment (30) contribute to simulated feelings (76) which ultimately ...

06/29/06 - 20060142985 - Modelling system
A modelling system (1) comprises a blood vessel simulating model (2) connected to a pump system (3) and mounted in the field of view of a polariscope system (4) and a camera system (7). The model (2) is mounted on an adjustable stand (5). The blood vessel simulating model (2) ...

06/29/06 - 20060142984 - Method for the reconstruction of three-dimensional objects
The invention relates to a method for the computer-aided reconstruction of a three-dimensional anatomical object (3) from diagnostic image data. First of all, a diagnostic image data set of the object (3) is acquired. Then a seed point (5) is set, starting from which the object is reconstructed within a ...

06/29/06 - 20060142983 - Tissue disorder imaging analysis
Methods and systems are described for quantitatively determining a score (150) for a patient having a disorder, e.g., a stroke, in a tissue, such as the brain, by analyzing both the extent and location of damage (110, 120, 130 AND 140) to the tissue caused by the disorder. ...

06/22/06 - 20060136186 - Modular computational models for predicting the pharmaceutical properties of chemical compounds
The methods of the invention allow for the construction and/or use of modular computational models to accurately predict the therapeutic properties, including both therapeutic potency and one or more ADMET properties, of all or part of a chemical compound. The modular computational models can be used to rapidly screen libraries ...

06/22/06 - 20060136185 - System modeling apparatus and method and controller designing system and method using the same
A system modeling apparatus and method and a controller designing system and method of performing a system modeling using the same includes applying a step input of a magnitude to a system of interest, sampling a number of outputs according to a predetermined sampling cycle in response to the step ...

06/22/06 - 20060136184 - Systems and methods for antibody engineering
Methods, computer systems, and computer program products for biopolymer engineering. A variant set for a biopolymer of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the biopolymer of interest and, for each respective position in the plurality of positions, substitutions for the respective ...

06/22/06 - 20060136183 - Virtual simulator method and system for neuromuscular training and certification via a communication network
A virtual simulator method and system via a communication network with possible physics law respect is used to create a virtual skill training environment for dexterity fulfillment of physical activities such as professional work, labour or craft activities, sport or even physical rehabilitation requirements where the skills or neuromuscular ability ...

06/22/06 - 20060136182 - Three dimensional construct for the design and fabrication of physiological fluidic networks
The present invention relates to methods for the design and fabrication of biological constructs, such as organ simulants or organ replacements, which contain complex microfluidic architecture. Designs of the present invention provide increased space in the lateral dimension, enabling a large number of small channels for small vessels. ...

06/08/06 - 20060122816 - Computer systems and methods for subdividing a complex disease into component diseases
A method for identifying a quantitative trait loci for a complex trait that is exhibited by a plurality of organisms in a population. The population is divided into a plurality of sub-populations using a classification scheme. Depending on what is known about the population, either a supervised or unsupervised classification ...

05/25/06 - 20060111883 - Method, an installation, and a computer program for estimating the initial size of a population of nucleic acids, in particular by pcr
a) providing a model of the effectiveness (En) of the PCR, the model comprising a constant stage (E0) followed by a non-constant stage, the stages being united by a changeover region having a changeover index (CEEP); b) using the model of effectiveness to express a relationship between the changeover index ...

05/11/06 - 20060100838 - Method and apparatus for producing a biomaterial product
A development tool 2 includes a plurality of measuring tools 71 to 76 and an industrial process simulation device 60. The simulation device 60 simulates a whole industrial scale bioprocess in order to obtain acceptable operating parameters for the industrial scale bioprocess. The measuring tools 71 to 76 enable various ...

05/04/06 - 20060095242 - System and method for determining condyle displacement utilizing electronic models of dental impressions having a common coordinate system
A system and method for determining condyle displacement during jaw articulation includes a physical model with corresponding reference points. The physical model is positioned and scanned to obtain positional data representing a first and second bite position. This positional data is used to generate a transformation matrix. The position of ...

05/04/06 - 20060095241 - Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
The subject invention provides systems and methods that facilitate AIDS vaccine cocktail assembly which optimize an optimization criterion, via machine learning algorithms, e.g., a greedy algorithm, an expectation-maximization (EM) algorithm, etc. Such assembly can be utilized to generate vaccine cocktails for species of pathogens that evolve quickly under immune pressure ...

04/27/06 - 20060089825 - Scanning kelvin microprobe system and process for biomolecule microassay
There is provided a system and process for detecting biomolecular interaction on a substrate having a biomolecule immobilized on a surface of the substrate. The system and process incorporate a scanning Kelvin microprobe (SKM) capable of analyzing surface topography as well as a contact potential difference image signal. Also provided ...

04/27/06 - 20060089824 - Methods and systems for drug screening and computational modeling
A method for screening a test compound for potential efficacy in treatment of a disorder includes creating a first computer model representative of a volume of disease-afflicted neural tissue exposed to the test compound; and providing an initial excitation to the first computer model. Following a selected computation interval, a ...

04/20/06 - 20060085175 - Method and device for assisting in a tissue treatment
A method for planning to treat tissue by administering a substance which emits energy or can interact with administered energy to a body, such as body tissue, wherein a dispersion of the substance in the body is simulated, and to a system or device for planning administering a substance and ...

03/16/06 - 20060058988 - Method and apparatus for computer modeling a joint
The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis. ...

02/23/06 - 20060041414 - System and method for improved computer drug design
A system and method for computer-aided drug design employs adaptive sampling and iterative fitting of mult-atomic subunits. The iterative fitting is performed by successive perturbation of the location of the multi-atomic subunits in directions that reduces potential energy. ...

02/23/06 - 20060041413 - System and method for optimizing animal production based on dynamic nutrient information
A system for generating an animal feed formulation based on utilization of nutrients received by an animal. The system includes a simulator engine configured to generate a set of animal requirements based on characteristics of an animal and to generate animal feed formulation input based at least in part on ...

02/23/06 - 20060041412 - System and method for optimizing animal production based on empirical feedback
A system for generating optimized values for variable inputs to an animal production system. The system includes a simulator engine configured to receive a plurality of animal information inputs and generate a performance projection. At least one of the animal information inputs is designated as a variable input. The system ...

02/16/06 - 20060036420 - Three-dimensional model of a complex between a fc epsilon receptor alpha chain and a fc region of an ige antibody and uses thereof
The present invention includes three-dimensional models of complexes between antibody receptor proteins, such as FcεRIα proteins, and antibodies, such as Fc-Cε3/Cε4 regions of IgE antibodies, as well as methods to produce such models. The present invention also includes muteins having increased stability and/or antibody binding activity, as well as methods ...

02/16/06 - 20060036419 - System and method for animal production optimization
A system for generating optimized values for variable inputs to an animal production system. The system includes a simulator engine configured to receive a plurality of animal information inputs and generate a performance projection, wherein at least one of the animal information inputs is designated as a variable input and ...

02/09/06 - 20060031052 - Optimizing genome-wide mutation analysis of chromosomes and genes
A method of genome-wide testing of gene copy number at the genetically most important loci to determine whether the gene and/or its selected larger surrounding chromosome region is rearranged to result in an unbalanced abnormality in one or more subjects, said method including selecting multiple gene loci of said DNAs ...

02/09/06 - 20060031051 - Optimizing genome-wide mutation analysis of chromosomes and genes
A method of genome-wide testing of gene copy number at the genetically most important loci to determine whether the gene and/or its selected larger surrounding chromosome region is rearranged to result in an unbalanced abnormality in one or more subjects, said method including selecting multiple gene loci of said DNAs ...

02/09/06 - 20060031050 - Radiation dose uncertainty code
Systems, machine readable storage, and methods for solving a respiratory tract model of radiation dosage. Steps include selecting input parameters associated with a respiratory tract model, computing a probability density function for the input parameters, and solving the respiratory tract model using the computed probability density functions. ...

02/02/06 - 20060025977 - Computational method and apparatus for predicting polypeptide aggregation or solubility
A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in hydrophobicity (ΔHydr) between the reference polypeptide and a modified polypeptide, calculating the difference in β-sheet propensity (ΔΔGcoil-α+ΔΔGβ-coil) between the reference polypeptide and modified ...

01/26/06 - 20060020440 - Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or processes (i.e., metabolic process) thought to be involved in disease pathogenesis. Molecular flux rates within the one or more biochemical processes ...

01/26/06 - 20060020439 - System and method for discovering gene regulatory models and genetic networks using relational fuzzy models
A system, method and program product for discovering gene regulatory models using relational fuzzy models. A system is providing that includes a data selection system that clusters gene expression data into a set of clusters and identifies a representative subset of genes from the set of clusters; and a relational ...

12/22/05 - 20050283347 - Apparatus and method for processing information concerning biological condition, system, program and recording medium for managing information concerning biological condition
A system provided in accordance with the present invention comprises a sever unit (100), which serves as an apparatus for processing information concerning a biological condition information, and a client unit (200), which serves as an information terminal of a provider of the information on the biological condition communicably connected ...

12/08/05 - 20050273306 - Hybrid classical-quantum computer architecture for molecular modeling
A method of simulating a molecular system using a hybrid computer is provided. The hybrid computer comprises a classical computer and a quantum computer. The method uses atomic coordinates {right arrow over (R)}n and atomic charges Zn of a molecular system to compute a ground state energy of the molecular ...

12/08/05 - 20050273305 - Network models of biochemical pathways
This invention describes computer based systems and methods for modeling and simulation of biochemical networks of pathways, including metabolic, signal transduction and regulatory pathways within a cell or across cells. The invention comprises systems and methods for building the models and for using the models for analysis and information retrieval, ...

12/01/05 - 20050267723 - Physiocochemical process modelling system
A modelling system models a physicochemical process such as a chemical reaction process (1) with mass and heat transfers across liquid, gas, and solid phase boundaries. A model editor receives a components file (2(a)) of chemical species, a natural language process description, (2(b)), a scenarios file (2(c)) having multiple rows ...

12/01/05 - 20050267722 - Computer-assisted external fixation apparatus and method
A computer-assisted external fixation apparatus and method comprises an external fixation application for assisting, guiding, and planning an external fixation procedure. The external fixation application cooperates with a tracking system to acquire kinematic data corresponding to a selected joint during manipulation of the selected joint and/or acquire image data of ...

12/01/05 - 20050267721 - Network models of biological complex systems
This invention describes computer based systems and methods for modeling and simulation of complex biological systems from the cellular, or subcellular, to the organism and population level, for using said models to predict functions of components of the biological systems and to simulate physiological and pathological states at the various ...

12/01/05 - 20050267720 - Methods and systems for the identification of components of mammalian biochemical networks as targets for therapeutic agents
Systems and methods for modeling the interactions of the several genes, proteins and other components of a cell, employing mathematical techniques to represent the interrelationships between the cell components and the manipulation of the dynamics of the cell to determine which components of a cell may be targets for interaction ...

11/17/05 - 20050256690 - Simulation system for simulating material concentration in a living body and storage medium
A system for computer simulation of object material concentration in a living body using a biological simulation model configured by a blocks readily corresponding to organs of a living body is provided. The functions of organs in a living body related to the object material are described using the biological ...

11/17/05 - 20050256689 - Method and system for measuring attributes on a three-dimenslonal object
The method of this invention, and the apparatus which implements it, provides a way of sampling points on the surface of a portion of a rigid or semi-rigid object, which might be an anatomical body. Points are sampled by a moveable contact probe which emits a sonic waveform under the ...

11/10/05 - 20050251375 - Method for simulating the dynamics of biological networks in silico
A stochastic simulation method for simulating the kinetics of chemical networks implemented using reprogrammable Field Programmable Gate Array (FPGA) devices. Such devices, built as an array of simple configurable logic blocks embedded in a programmable interconnection matrix, implement highly parallel architectures comparable in complexity to biochemical networks. Circuits based on ...

10/27/05 - 20050240385 - System and method for determining radius of gyration, molecular weight, and intrinsic viscosity of a polymeric distribution using gel permeation chromatography and light scattering detection
A system and method for analyzing data from a gel permeation chromatography (GPC) or size exclusion chromatography (SEC) system fro determining a polymeric sample's radius of gyration. Data from two or more detectors is used with a least-squares minimization fit. A novel method includes the simultaneous determination of a sample's ...

10/20/05 - 20050234691 - Crop yield prediction
Crop yield may be assessed and predicted using a piecewise linear regression method with break point and various weather and agricultural parameters, such as NDVI, surface parameters (soil moisture and surface temperature) and rainfall data. These parameters may help aid in estimating and predicting crop conditions. The overall crop production ...

10/13/05 - 20050228626 - System and method for health analysis
One or more personalized models of one or more of a user's organs, systems, and/or the like may, for example, be run, and/or biological measurement data may, for instance, be obtained for the user. Comparison and/or the like of model output and obtained biological data may, for instance, be performed. ...

09/29/05 - 20050216243 - Computer-simulated virtual reality environments for evaluation of neurobehavioral performance
A virtual reality (VR)-based test battery wherein various neurobehavioral performance skills, including motor skills, sensory-perceptual skills, attention, and decision-making can be measured in human subjects. The invention can be used as a screening method within a virtual environment to provide an overall measure of general brain function relating to behavioral ...

09/22/05 - 20050209838 - Fast microarray expression data analysis method for network exploration
A method for performing network reconstruction is provided. The method includes the steps of selecting a predictor set of features, adding a complement to the predictor set based on a quality of prediction, checking to see if all of the features of the predictor set are repeated, and then removing ...

09/22/05 - 20050209837 - Bactericidal/permeability-increasing protein: crystallization, x-ray diffraction, three-dimensional structure determination, rational drug design and molecular modeling or related proteins
The present invention solves the three-dimensional structure of BPI and thereby provides atomic coordinates of BPI from the analysis of x-ray diffraction patterns of sufficiently high resolution for three-dimensional structure determination of the protein, as well as methods for rational drug design, based on using amino acid sequence data and/or ...

09/15/05 - 20050203726 - System and method for generating an electronic model for a dental impression having a common coordinate system
A system and method for generating an electronic model for a dental impression having a common coordinate system. The system includes two scanning apparatus for positioning physical objects within a scanning device when generating an electronic model corresponding to each of the physical objects; a data processing system for processing ...

09/08/05 - 20050197814 - System and method for designing a physiometric implant system
A system improves the design of artificial implant components for use in joint replacement surgeries. The system includes an anthropometric static image data analyzer, an implant model data generator, a kinematic model simulator, and a dynamic response data analyzer. The implant model data generator may also use image data of ...

08/25/05 - 20050187749 - Method, system, and computer program for performing carbohydrate/insulin calculation based upon food weight
A technique is disclosed by which a weight scale, having electronic output, is couplable to a processing device such as a computer, and preferably, a hand-held computer, PDA, cell phone or the like. The processing device is configured to receive weight inputs from the weight scale and identification information of ...

08/25/05 - 20050187748 - Methods of modeling physical properties of chemical mixtures and articles of use
Included are methods for modeling at least one physical property of a mixture of at least two chemical species. One or more chemical species of the mixture are approximated or represented by at least one conceptual segment. The conceptual segments are then used to compute at least one physical property ...

08/25/05 - 20050187747 - Method and apparatus for improved simulation of chemical and biochemical reactions
An integrated system for modeling, simulating and analyzing chemical and biochemical reactions includes a modeling environment for constructing a model of a chemical or biochemical reaction. The system also includes a simulation engine accepting as input said constructed model of the chemical or biochemical reaction and generating as output an ...

08/25/05 - 20050187746 - Method and apparatus for improved modeling of chemical and biochemical reactions
An system for improved modeling of chemical and biological systems includes a graphical user interface accepting user commands and input for constructing a model of a biological system or a chemical reaction. The system also includes a simulation engine accepting as input said constructed model of the chemical reaction or ...

08/25/05 - 20050187745 - Method and apparatus facilitating communication with a simulation environment
A system for modifying a model of a chemical reaction or biochemical process responsive to experimental results generated by an in situ experiment conducted on an experimental platform includes a simulation engine and an analysis environment. The simulation engine generates an expected result from a model of the chemical reaction ...

07/28/05 - 20050165594 - System, method and apparatus for causal implication analysis in biological networks
Described are methods, systems and apparatus for hypothesizing a biological relationship in a biological system. A database of biological assertions is provided consisting of biological elements, relationships among the biological elements, and relationship descriptors characterizing the properties of the elements and relationships. A biological element may be selected from the ...

06/16/05 - 20050131663 - Simulating patient-specific outcomes
The invention encompasses systems, methods, and apparatus for predicting and monitoring an individual's response to a therapeutic regimen. The invention includes multiple virtual patients, an associating subsystem operable to associate the subject with one or more of the virtual patients, and a simulation engine operable to apply one or more ...

06/16/05 - 20050131662 - Method and system for modelling bone structure
The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains and stresses due to the specific forces acting on bone during function, ...

06/09/05 - 20050125210 - System and method for providing a canonical structural representation of chemical compounds
Embodiments of the present invention provide a system and method for representing chemical compounds in a canonical manner that enables one to associate multiple structures, including proto-stereomers, with a compound. Embodiments of the present invention can receive an input representation of a structure of a compound, neutralize acidic and basic ...

06/02/05 - 20050119869 - Annotation method
The invention relates to a method for annotating protein sequences consistently, using disparate secondary database protein family information. In the method, information relating to the family to which a protein belongs is derived from two or more secondary databases (2DBs), each 2DB being generated by a different modelling approach and ...



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