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Surgery: Light, Thermal, And Electrical Application > Light, Thermal, And Electrical Application > Electrical Therapeutic Systems > Combined With Nonelectrical Therapy

Combined With Nonelectrical Therapy

Combined With Nonelectrical Therapy patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/14/06 - 20060282123 - Electrical devices and anti-scarring agents
Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal. ...

11/02/06 - 20060247686 - Implantable device for delivering cardiac drug therapy
An implantable medical device in which an electrogram is recorded and analyzed in order to detect changes indicative of cardiac ischemia. Cardiac ischemia may be detected by recording an electrogram from a sensing channel of the device and comparing the recorded electrogram with a reference electrogram. If cardiac ischemia is ...

11/02/06 - 20060247685 - System and method for detecting hypoglycemia based on a paced depolarization integral using an implantable medical device
Techniques are provided for use with an implantable medical device such as a pacemaker or implantable cardioverter/defibrillator (ICD) for predicting and detecting hypoglycemia. In one example, the device tracks changes in a paced depolarization integral (PDI). A significant increase in PDI over a relatively short period of time indicates the ...

10/05/06 - 20060224192 - Electroporation devices
Improved devices and methods for performing electroporation-mediated delivery agents to cells is described. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal ...

10/05/06 - 20060224191 - Systems and methods for monitoring a patient's neurological disease state
The present invention provides a system for providing neurological disease state information to a patient. The system comprises one or more sensors that sense at least one signal that comprise feature(s) that are indicative of a neurological disease state. A signal processing assembly is in communication with the one or ...

10/05/06 - 20060224190 - System and method for detecting heart failure and pulmonary edema based on ventricular end-diastolic pressure using an implantable medical device
Techniques are provided for detecting left ventricular end diastolic pressure (LV EDP) using a pressure sensor implanted within the heart of a patient and for detecting and evaluating heart failure and pulmonary edema based on LV EDP. Briefly, the peak of the R-wave of an intracardiac electrogram (IEGM) is used ...

09/21/06 - 20060212078 - Methods and apparatus for treating congestive heart failure
Methods and apparatus are provided for treating congestive heart failure, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, ...

09/14/06 - 20060206150 - Methods and apparatus for treating acute myocardial infarction
Methods and apparatus are provided for treating acute myocardial infarction, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, ...

09/14/06 - 20060206149 - Methods and compositions for treating a disease condition in a subject
Methods for treating a disease condition in a subject are provided. The subject methods include selectively modulating at least one biological activity of advential tissue in a manner effective to treat the disease condition. Also provided are compositions, kits and systems for use in practicing the subject methods. ...

08/31/06 - 20060195146 - System and method for selectively stimulating different body parts
Devices and methods are provided for electrically stimulating a predetermined body part of a mammal. The method includes placing at least one electrode in proximity to the mammal's skin, injecting an electrically conductive gel into the body of the mammal so as to form a conductive gel pathway extending at ...

08/24/06 - 20060190044 - Cell therapy and neural stimulation for cardiac repair
A method and system to enhance cell, gene and/or cytokine therapy for cardiac repair in a mammal. ...

07/27/06 - 20060167501 - Method to enhance progenitor or genetically-modified cell therapy
A method is provided including selecting a patient suffering from a condition, administering cells to the patient selected from the group consisting of: progenitor cells and genetically-modified cells, applying an electrical current to a site of the patient in a vicinity of nervous tissue, and configuring the current to stimulate ...

07/27/06 - 20060167500 - Neurostimulator
Methods and devices of stimulating nerves are disclosed. In one embodiment adapted for stimulating excitable tissue, the invention includes drive circuitry (12), an acoustic transducer (14) and a pair of electrodes (28). ...

05/18/06 - 20060106427 - Electrical stimulation unit and waterbath system
A method for treating an infected area on a subject, comprising the steps of: exposing the infected area to an aqueous solution; and providing direct current to the aqueous solution to treat the infected area. ...

05/18/06 - 20060106426 - Sphero cylindrical eye refraction system using fluid focus electrostatically variable lenses
Optical devices, systems, and methods can produce and/or measure cylindrical (as well as spherical) lens shapes throughout a range of both powers and cylindrical axes. Fluid focus lenses employ electrical potentials to vary the shape of a fluid/fluid interface between two immiscible fluids having differing indices of refractions by controlling ...

04/27/06 - 20060089674 - Method of treating biological materials with translating electrical fields and electrode polarity reversal
A method and apparatus are provided for treating biological cellular material with a treating agent using pulsed electrical fields provided by a waveform generator (12). The treatment method includes obtaining an electrode assembly which includes three or more parallel rows of individual electrodes (19). The electrode assembly is applied to ...

04/06/06 - 20060074451 - Method and system for the prediction of cardiac arrhythmias, myocardial ischemia, and other diseased condition of the heart associated with elevated sympathetic neural discharges
Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia, myocardial ischemia, congestive heart failure and other diseased conditions of the heart associated with elevated sympathetic neural discharges in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a ...

03/30/06 - 20060069410 - Method and system for terminating an atrial arrhythmia
A method and system is provided for responding, from internally within a patient, to an atrial arrhythmia in a heart including measuring from within the patient at least one electrocardiogram characteristic indicative of the atrial arrhythmia, and controlling from within the patient drug therapy delivery to the patient responsive to ...

03/09/06 - 20060052828 - Methods for stimulating a nerve root ganglion
Some embodiments of the present invention provide stimulation systems and components for selective stimulation and/or neuromodulation of one or more nerve root ganglia through implantation of an electrode on, in or around a nerve root ganglia. Some other embodiments of the present invention provide methods for selective neurostimulation of one ...

03/02/06 - 20060047318 - Method and apparatus to deliver drug and pacing therapy for treatment of cardiac disorders
A drug delivery system uses an electrically sensitive polymer to store a drug and applies an electric field onto the electrically sensitive polymer for quantitatively and temporally controlled drug delivery. In one embodiment, the drug delivery system is part of a cardiac rhythm management (CRM) system that includes an implantable ...

02/23/06 - 20060041277 - Methods and apparatus for renal neuromodulation
Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive ...

02/23/06 - 20060041276 - Method and apparatus for delivering combined electrical and drug therapies
A cardiac rhythm management (CRM) system includes an implantable medical device that delivers combined electrical and drug therapies. The implantable medical device includes a drug reservoir that is refillable after implantation. In one embodiment, the implantable medical device includes an implantable housing encapsulating a pulse generator circuit and a drug ...

02/16/06 - 20060036286 - Monitoring, preventing, and treating rejection of transplanted organs
An implantable system control unit (SCU) includes means for measuring tissue impedance or other condition to determine allograft health, in order to predict or detect allograft rejection. The SCU also includes at least two electrodes coupled to means for delivering electrical stimulation to a patient within whom the device is ...

02/09/06 - 20060030889 - Local cardiac motion control using applied signals and mechanical force
Apparatus (18) for performing a medical procedure on a beating heart (20) includes a mechanical stabilization element (25), a surface (27) of which is adapted to be applied to a segment (24) of the heart to reduce motion of the segment. One or more electrodes (100) are fixed to the ...

02/02/06 - 20060025821 - Methods and devices for renal nerve blocking
A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from the kidney. The device can be a drug pump or a drug eluding implant for targeted delivery of ...

01/19/06 - 20060015146 - Method and apparatus for controlled gene or protein delivery
An implantable system which includes a gene/protein delivery device and a pulse generator, as well as method of preparing the gene/protein delivery device and using the system, are provided. In one embodiment, the implantable system detects a predetermined condition or event and, in response, delivers gene(s) and/or protein(s) in conjunction ...

01/12/06 - 20060009806 - Anti-infective medical device
Implantable medical devices (IMDS) having anti-infective properties are described. Anti-infective agents are disposed in, on, or about at least a portion of a surface of the medical device. The anti-infective agents are disposed in or on a vehicle, which may be in the form of a coating layer or covering. ...

01/05/06 - 20060004414 - Method and system for the prediction of cardiac arrhythmias, myocardial ischemia, and other diseased condition of the heart associated with elevated sympathetic neural discharges
Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia, myocardial ischemia, congestive heart failure and other diseased conditions of the heart associated with elevated sympathetic neural discharges in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a ...

01/05/06 - 20060004413 - Method and system for the prediction of cardiac arrhythmias
Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a patient from the left stellate ganglion, the thoracic ganglia, or both, and detecting increases in the sympathetic neural ...

11/24/05 - 20050261741 - Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device
A method and device for delivering ventricular resynchronization pacing therapy in conjunction with electrical stimulation of nerves which alter the activity of the autonomic nervous system is disclosed. Such therapies may be delivered by an implantable device and are useful in preventing the deleterious ventricular remodeling which occurs as a ...

11/17/05 - 20050256541 - Catheter with temporary stimulation electrode
A catheter has at least one removable, temporary stimulation electrode for positioning of the catheter prior to delivery of a therapeutic substance, such as pharmaceutical or biological therapy, to the nervous system of a patient. A stylet having at least one temporary stimulation electrode disposed at its distal end is ...

11/17/05 - 20050256540 - Apparatus and method for movement of electricity or fluid into and out of the body
An apparatus for communication between a site within a body deep to the skin and a source, depot, reservoir, device, machine, or power source external to the body via the mouth of the body, comprising an implant for placement in tooth-supporting bone, the implant having a first portion extending into ...

10/27/05 - 20050240231 - Methods and apparatus for testing disruption of a vagal nerve
Method and apparatus for disrupting a gastric vagal nerve in the gastroesophageal region and testing the function and disruption of the vagal nerve. In one example embodiment, a treatment device applies ultrasound at a high energy level, such as high intensity focused ultrasound, to a vagal nerve to disrupt it ...

10/27/05 - 20050240230 - Therapeutic device for hands and wrists
The invention claimed herein presents a therapeutic device for hands and wrists that provides massage, thermal and electrical stimulation therapy. For full inner and outer hand therapy, upper housing 4 is closed and the user's hands and wrists are placed between lower panel 8 and upper panel 10. Upper housing ...

10/20/05 - 20050234516 - Treatment kit, composite structure, electric exciter, and cosmetic treatment method
A treatment kit may include an electric exciter including at least two electrodes and a composite structure not including any electrodes. The composite structure may include a first surface configured to be applied to a zone to be treated and a second surface opposite from the first surface. The composite ...

10/20/05 - 20050234515 - Microperfusive electrical stimulation
A method of treating a patient in cardiac arrest (e.g., in fibrillation, electrochemical dissociation, or asystole), the method comprising delivering an agent for enhancement of cardiac function to the coronary arteries of the patient; and microperfusing the patient's cardiac tissue by electromagnetically stimulating the cardiac tissue at an energy level ...

10/13/05 - 20050228452 - Steerable catheters and methods for using them
An apparatus for treating tissue includes a flexible catheter including a proximal end, a distal end for introduction into a chamber of a heart, a transparent balloon carried by the distal end, an optical imaging assembly carried by the distal end for imaging tissue structures beyond the distal end through ...

10/06/05 - 20050222628 - Implantable device for pain control and other medical treatments
A device for pain control or other medical treatments of a patient. The device includes an implantable unit for implantation under the skin of a patient. The implantable unit includes a drug chamber containing a fluid drug, a tube for delivering the fluid drug to a location in the patient's ...

09/29/05 - 20050216064 - Sensitivity analysis for selecting therapy parameter sets
Techniques for controlling delivery of a therapy to a patient by a medical device, such as an implantable medical device (IMD), involve a sensitivity analysis of a performance metric. The performance metric may relate to efficacy or side effects of the therapy. For example, the performance metric may comprise a ...

09/22/05 - 20050209645 - Collecting posture information to evaluate therapy
A medical device delivers a therapy to a patient. The medical device may identify posture events, e.g., periodically determine a posture of the patient and/or identify posture transitions by the patient, and associate each determined posture event with a current therapy parameter set. A value of at least one posture ...

09/22/05 - 20050209644 - Collecting activity information to evaluate therapy
A medical device delivers a therapy to a patient. The medical device may periodically determine an activity level of the patient, and associate each determined activity level with a current therapy parameter set. A value of at least one activity metric is determined for each of a plurality of therapy ...

09/22/05 - 20050209643 - Controlling therapy based on sleep quality
A medical device, such as an implantable medical device (IMD), determines values for one or more metrics that indicate the quality of a patient's sleep, and controls delivery of a therapy based on the sleep quality metric values. For example, the medical device may compare a sleep quality metric value ...

09/01/05 - 20050192638 - Methods and devices for renal nerve blocking
A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from the kidney. The device can be a drug pump or a drug eluding implant for targeted delivery of ...

09/01/05 - 20050192637 - Method and apparatus for device controlled gene expression
A gene regulatory system controls gene therapy by emitting one or more forms of energy that regulate gene expression by triggering promoters. The system includes a sensor to sense a signal indicative of a need for the gene therapy as well as responses to the gene therapy. The regulation of ...

08/18/05 - 20050182449 - Methods for electrosurgical electrolysis
Methods for electrosurgical electrolysis for treating tissue within a body, including methods that operate in an electrolyzable medium, including an aqueous electrolyzable medium, by means of electrolysis, and optionally by means of oxy-hydrogen combustion for use in treatment, including therapeutic methods of electrolysis to effect advantageous tissue changes. ...

08/11/05 - 20050177192 - Neurostimulation for affecting sleep disorders
A method of affecting a sleep disorder in a subject having the sleep disorder and a method of affecting a normal awakeness-sleep cycle in a subject having an abnormal awakeness-sleep cycle, said methods comprising: a) identifying at least one nucleus in a brain of the subject, said nucleus being a ...

07/14/05 - 20050154419 - Methods and systems for stimulating a nerve originating in an upper cervical spine area to treat a medical condition
Methods of treating a medical condition of a patient include applying at least one stimulus to a target nerve within the patient with an implanted system control unit in accordance with one or more stimulation parameters. The target nerve may include any nerve originating in an upper cervical spine area ...

07/07/05 - 20050149124 - Electrical stimulation unit and waterbath system
A method for treating an infected area on a subject, comprising the steps of: exposing the infected area to an aqueous solution; and providing direct current to the aqueous solution to treat the infected area. ...

06/23/05 - 20050137626 - Drug delivery system and method employing external drug delivery device in conjunction with computer network
A cardiac rhythm management system detects a condition indicative of acute decompensated heart failure and, in response, delivering a drug therapy. The system includes an implantable device communicating with a transdermal drug delivery device. The transdermal drug delivery device delivers a pharmaceutical substance in response to a detection of the ...

06/02/05 - 20050119704 - Control of cardiac arrhythmias by modification of neuronal conduction within fat pads of the heart
To control cardiac arrhythmias, various conduction-modifying agents include biopolymers, fibroblasts, neurotoxins, and growth factors are introduced either epicardially or endocardially to the fat pads in proximity to the ganglia therein. Any desired technique may be used for injection, including injection from a catheter inserted percutaneously, or direct injection through the ...



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