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Organic Compounds -- Part Of The Class 532-570 Series > Azo Compounds Containing Formaldehyde Reaction Product As The Coupling Component > Carbohydrates Or Derivatives > Nitrogen Containing > Dna Or Rna Fragments Or Modified Forms Thereof (e.g., Genes, Etc.) > Synthesis Of Polynucleotides Or Oligonucleotides

Synthesis Of Polynucleotides Or Oligonucleotides

Synthesis Of Polynucleotides Or Oligonucleotides patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

09/28/06 - 20060217546 - 3-deoxypentopyranosyl nucleic acid, its production and its use
This invention relates to a process for preparing a 3′-deoxypentopyranosyl oligomer, which includes the steps of bonding a 4′-protected-3′-deoxypentopyranosyl nucleoside to a solid support, deprotecting the nucleoside at the 4′-position, reacting the 2′OH group with a 4′-protected-3′-deoxypentopyranosyl nucleoside phosphoramidite in the presence of a coupling reagent, and oxidizing the reaction ...

08/24/06 - 20060189799 - Method of preventing modification of synthetic oligonucleotides
The present invention relates to a method of preventing modification of a synthetic oligonucleotide or oligonucleotide analog during removal of at least one cyanoethyl protecting group from the oligonucleotide or oligonucleotide analog. The method involves contacting the oligonucleotide or oligonucleotide analog with a basic solution having at least one acrylonitrile ...

08/10/06 - 20060178507 - Fluorous oligonucleotide reagents and affinity purification of oligonucleotides
Fluorous-tagged oligonucleotide reagents and an oligonucleotide purification methodology making use thereof, the method comprising: Synthesizing oligonucleotides using oligonucleotide reagents each bearing at least one fluorous group to yield a mixture of synthesis products and reagents, the mixture including at least one target synthesized oligonucleotide bearing at least one fluorous group; ...

07/06/06 - 20060149051 - Method of preparing an acylimidazolium-type reagent
The invention relates to a method of preparing an acylimidazolium-type reagent. More specifically, the invention relates to a salt of N-(benzyloxycarbonyl)-N′-methylimidazolium. The inventive method of preparing an acylimidazolium-type reagent is characterised in that it is obtained by: (i) reacting a reagent comprising a —COX group having formula (II) and an ...

06/22/06 - 20060135759 - Reusable universal polymer support for repetitive oligonucleotide synthesis
Present invention provides a reusable universal polymer support for repetitive Oligonucleotide synthesis and a method of synthesis thereof. ...

03/23/06 - 20060063925 - Nucleic acid anchoring system comprising covalent linkage of an oligonucleotide to a solid support
The anchoring system generally comprises a solid support and a chemical linking moiety useful for ether formation with another chemical moiety on a nucleic acid molecule. The present invention further contemplates methods for anchoring a nucleic acid molecule to a solid support via a covalent linkage. The anchoring system of ...

03/16/06 - 20060058518 - Method for bisulfite treatment
The present application is directed to a method for performing a bisulfite reaction to determine methylation positions in a nucleic acid, i.e. methylated and non-methylated cytosines, whereby the nucleic acid is incubated in a solution comprising the nucleic acid for a time period of 1.5 to 3.5 hours at a ...

02/23/06 - 20060041115 - Methods for preparing oligonucleotides having chiral phosphorothioate linkages
Methods are provided for preparing internucleotide phosphorothioate linkages that are enriched in the Sp or Rp enantiomer comprising coupling a synthon with a 2′-substituted nucleoside in the presence of coupling agent that is selected to enhance either the Rp or Spenantiomer according to its pKa. ...

02/16/06 - 20060036090 - Method for the chemical synthesis of oligonucleotides
The present invention features novel compositions, linkers, derivatized solid supports, and methods for the efficient solid phase synthesis of oligonucleotides, including RNA, DNA, RNA-DNA chimeras, and analogs thereof. ...

06/23/05 - 20050137390 - Process for the synthesis of oligomeric compounds
Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants. ...

06/23/05 - 20050137389 - Methods and compositions for chromosome-specific staining
The invention relates generally to the field of cytogenetics, and more particularly to methods for identifying and classifying chromosomes. ...



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