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Chemistry: Natural Resins Or Derivatives; Peptides Or Proteins; Lignins Or Reaction Products Thereof > Proteins, I.e., More Than 100 Amino Acid Residues > Chemical Modification Or The Reaction Product Thereof, E.g., Covalent Attachment Or Coupling, Etc.

Chemical Modification Or The Reaction Product Thereof, E.g., Covalent Attachment Or Coupling, Etc.

Chemical Modification Or The Reaction Product Thereof, E.g., Covalent Attachment Or Coupling, Etc. patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

08/10/06 - 20060178505 - Thioester-terminated water soluble polymers and method of modifying the n-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating a polymer specifically to the α-amine of a polypeptide. The invention provides monofunctional, bifunctional, and multifunctional PEGs and related polymers having a terminal thioester moiety capable of specifically conjugating to the α-amine of a polypeptide having a cysteine or histidine residue at ...

07/27/06 - 20060167233 - One-step reduction and alkylation of proteins
The present invention relates generally to the field of analyzing proteins and more specifically to the reduction and alkylation of protein samples during protein analysis. A novel composition and method for reducing and alkylating proteins is disclosed. A novel reagent including a combination of a volatile reducing agent, a volatile ...

06/15/06 - 20060128948 - Biological low-molecular-weight derivatives
The crosslinking agents and condensing agents that have been employed in biological adhesives and in treating medical devices such as cardiac valves are non-natural compounds synthesized artificially. Thus, they are not metabolized in vivo and exhibit toxicity to living bodies. These compounds are thus used only in a restricted amount ...

03/09/06 - 20060052586 - Process for preparation of mixtures of polypeptides using purified hydrobromic acid
The subject invention provides an improved process for obtaining a mixture of polypeptides having nonuniform amino acid sequences, where each polypeptide consists essentially of alanine, glutamic acid, tyrosine and lysine where the resulting mixture of polypeptides comprises less than 0.3% brominated tyrosine and less than 1000 ppm metal ion impurities. ...

01/12/06 - 20060009623 - C-terminal attachment of ligands to proteins for immobilization onto a support
The present invention provides methods of immobilizing proteins onto a support, using a cellular expression system or a cell-free expression system, to attach a ligand to the C-terminus of the protein, by an intein-mediated or a puromycin-mediated approach. A method for improving the efficiency of intein-mediated ligand attachment is also ...

01/12/06 - 20060009622 - Conjugates of therapeutic or cytotoxic agents and biologically active peptides
The invention features conjugates of therapeutic or cytotoxic agents and biologically active peptides and methods of use thereof. ...



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