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Chemistry: Natural Resins Or Derivatives; Peptides Or Proteins; Lignins Or Reaction Products Thereof > Peptides Of 3 To 100 Amino Acid Residues > 25 Or More Amino Acid Residues In Defined Sequence

25 Or More Amino Acid Residues In Defined Sequence

25 Or More Amino Acid Residues In Defined Sequence patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/07/06 - 20060276624 - Synthesis using peptide intermediate fragments
Methods for the solid phase synthesis of T-20 peptides and peptide intermediates, in particular methods involving synthesizing T-20 peptide intermediates at low loading factors to produce products having excellent purity and yield. ...

11/30/06 - 20060270831 - Novel peptide dimers as agonists of the erythropoietin (epo) receptor, and associated methods of synthesis and use
Novel peptide dimers are provided that bind and activate the erythropoietin receptor (EPO-R) or otherwise act as an EPO agonist. The novel compounds have a first peptide chain R1 and a second peptide chain R2, wherein R1 and R2 may be the same or different, and are linked through a ...

11/16/06 - 20060258839 - G-type peptides to ameliorate atherosclerosis
This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The peptides are highly stable and readily administered via an oral route. ...

11/09/06 - 20060252917 - Methods for refolding conformationally constrained peptides
A method for refolding of conformationally constrained peptides is described, in which non-ionic detergents and other folding-additives increase yields of correctly folded bioactive peptides. ...

11/09/06 - 20060252916 - Modified glucagon-like peptide-1 analogs
The invention encompasses GLP-1 compounds containing a GLP-1 peptide or a GLP-1 peptide with an extended C-terminus that is modified with a reactive group that is capable of forming covalent bonds with a blood component to form a conjugate. The conjugates may be formed in vivo or ex vivo. Methods ...

11/09/06 - 20060252915 - Antimicrobial bolisin peptides
The invention relates to antibiotically effective peptides which are prepared for medical and commercial use by using biotechnological methods and chemical synthesis. The antibiotically effective peptides can be used in a suitable galenic formulation as medicaments/animal medicaments, food additives or as preservatives for the prevention of microbial contaminations of cosmetics, ...

11/02/06 - 20060247416 - Hiv gp41 hr2-derived synthetic peptides, and their use in therapy to inhibit transmission of human immunodeficiency virus
Provided are synthetic peptides based on a native sequence of HIV gp41 HR2 except that the synthetic peptides have a plurality of amino acid replacements comprising (a) a helix-promoting amino acid, or (b) a combination of helix-promoting amino acids, and charged amino acids introduced to form ion pairs in the ...

10/26/06 - 20060241281 - Peptidomimetic polymers for antifouling surfaces
Peptidomimetic polymers comprising one or more DOPA moieties and related coatings and composites. ...

09/28/06 - 20060217531 - Ligand (act-4-l) to a receptor on the surface of activated cd4+ t-cells
The invention provides ligands and fragments thereof to a receptor on the surface of activated CD4+ T-cells. An exemplary ligand is designated ACT-4-L-h-1. Preferred fragments include purified extracellular domains of ligands. The invention also provides humanized and human antibodies to the ligand. The invention further provides methods of using the ...

08/03/06 - 20060173163 - Synthesis using peptide intermediate fragments
Methods for the solid phase synthesis of T-1249 peptides and peptide intermediates, in particular methods involving synthesizing T-1249 peptide intermediates at low loading factors to produce products having excellent purity and yield. ...

08/03/06 - 20060173162 - Bactericidak anti-apoptotic, pro-inflammatory and anti-inflammatory peptides of heparin-binding protein (hbp)
The present invention relates to providing new peptide fragments derived from the sequence of heparin-binding protein (HBP) and/or human neutrophil elastase and using said fragments for the manufacture of a medicament for the treatment of Gram positive and/or Gram negative infections. Thus, the peptides of the inventions can be used ...

07/13/06 - 20060155109 - Novel physiologically active peptide and its use
The present invention relates to a peptide comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 35 and having an ability of binding to a receptor protein comprising an amino acid sequence identical to or substantially identical to an ...

07/13/06 - 20060155108 - Multiple branch peptide construction
Multiple branch peptide constructions formed from peptide-branches derived from the envelope transmembrane glycoprotein gp41 of HIV, and including the consensus sequence RQGY preceded by 0 to 4 amino acid residues and succeeded by 0 to 4 amino acid residues, most preferably RQGYS, show increased receptor affinity and prevent cell-to-cell fusion. ...

06/22/06 - 20060135747 - Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
The present invention provides novel Pancreatic Polypeptide Family (“PPF”) polypeptides and methods for their use. ...

04/20/06 - 20060084789 - Immunotherapeutic and immunoprphylactic reagents
The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with T lymphocytes in subjects having Rye grass pollen allergy and genetic sequences encoding same. These molecules are preferentially immunointeractive with T cells in subjects having a Rye grass pollen allergy. The molecules of ...

02/16/06 - 20060036072 - Short-warp peptide dye conjugate as contrast agent for optical diagnostic
The invention relates to compounds for tumor diagnosis that consist of conjugates of dyes with short-chain peptides, which are derived from vaso-active intestinal peptide, somatostatin or neurotensin, the use of these compounds as optical diagnostic agents, and diagnostic agents that contain these compounds. ...

01/26/06 - 20060020112 - Methods for identifying modulators of transcriptional activator protein interactions
The present invention relates to methods for identifying interacting regions of transcription factors, and methods for identifying agents which modulate the interactions, useful for affecting gene regulation, for example, cellular transformation. A site within residues 130-154 and within residues 343-358 in Stat3 were found to interact with the transcription factor ...

01/26/06 - 20060020111 - Method of aminoacylating trna
It is intended to provide a method of chemically synthesizing an aminoacyl tRNA which is completely different from the existing methods, namely, a highly efficient and practically usable method for synthesizing an aminoacyl tRNA whereby any nonnatural amino acid can be conveniently aminoacylated without a need for genetic engineering techniques ...

01/19/06 - 20060014928 - Scorpion peptide as hypotensive agent
The present invention provides isoformes from a peptide family belonging to South American scorpion Tityus serrulatus that acts as hypotensive agents by potentiating Bradykinin and, therefore, can be used as anti-hypertensive drugs. A peptide was firstly isolated from Tityus serrulatus venom and showed a strong and long-lasted hypotensive activity when ...

11/17/05 - 20050256302 - Novel peptides having camp producing activity
or an amino acid sequence derived from the amino acid sequence by deletion, substitution or addition of part of these amino acids and having the following characteristics (1) being expressed in the central nerve system, (2) strongly acting on a calcitonin receptor, and (3) promoting the cAMP-productivity of a cell, ...

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10/06/05 - 20050222383 - Prostasin substrates and inhibitors
The invention provides substrate specificity profiles for serine protease prostasin. Optimal prostasin substrate sequences, both to the prime side and non-prime side of the prostasin recognition site, are disclosed herein. The prostasin substrate sequences are used in designing substrates, inhibitors, and prodrugs. Prostasin inhibitors based on substrate specificity are also ...

08/25/05 - 20050187378 - Novel peptides conferring environmental stress resistance and fusion proteins including said peptides
The present invention relates to peptides comprising at least one sequence selected from the group consisting of oligopeptide sequences of at least about 10 but not more than about 50 continuous amino acid residues in the amino acid sequence of the C-terminal acidic tail (ATS), which can render fusion partner ...

08/04/05 - 20050171335 - Novel antimicrobial peptide and use thereof
wherein Xa of the formula (1) is a hydrophilic amino acid residue, n is an integer of from 1 to 6, two or more of the Xa may be the same or different from one another, S is a peptide represented by hydrophobic amino acid part-basic amino acid part-bridge part-basic ...

07/21/05 - 20050159586 - Linear gamma-carboxyglutamate rich conotoxins
The invention relates to linear γ-carboxyglutamate rich conotoxins, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvillsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and ...



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