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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai > Oxygen Containing Hetero Ring Oxygen Containing Hetero RingOxygen Containing Hetero Ring patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.02/01/07 - 20070027207 - Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates. ... 11/16/06 - 20060258736 - Dosing regimen This invention relates to a twice weekly administration of 3′-tert-Butyl-3′-N-tert-butyloxycarbonyl-4-deacetyl-3′-dephenyl-3′-N-debenzoyl-4-O-methoxycarbonyl-paclitaxel that has been found to reduce the neurotoxicity of the drug and allow for better patient compliance in the use of this oral cancer drug. ... 10/26/06 - 20060241170 - Methods and formulations of taxanes In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of a pharmaceutically active agent, wherein the agent is associated with a polymeric biocompatible material. ... 09/28/06 - 20060217436 - Process for the preparation of docetaxel trihydrate A method to prepare Docetaxel trihydrate using the mixture of acetone and water, which provides the product with good stability, less experiment time, less exposal to light, and avoids purity decreasing. The process is simple and easy to operate. ... 08/24/06 - 20060189679 - C10 cyclopropyl ester substituted taxane compositions Compositions comprising a taxane having a cyclopropyl ester substituent at C10, a keto substituent at C9, a hydroxy substituent at C7, a 2-furyl substituent at C3′ and an isobutoxycarbamate substituent at C3′. ... 08/10/06 - 20060178427 - Cytotoxic agents comprising new taxanes The invention relates to novel cytotoxic agents comprising taxanes and their therapeutic use as a result of delivering the taxanes to a specific cell population in a targeted fashion by chemically linking the taxane to a cell binding agent. ... 06/08/06 - 20060122259 - Cytotoxic agents comprising taxanes and their therapeutic use A cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more taxanes covalently bonded to a cell binding agent through a linking group, and (B) a pharmaceutically acceptable carrier, diluent ... 06/08/06 - 20060122258 - Taxane derivatives functionalized at the 14-position and a process for the preparation thereof A general process for the functionalization at the 14-position of 13-ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the disclosure. The conversion of compounds of formula II in compounds of formula III, wherein the substituents are as defined in the ... 06/01/06 - 20060116420 - Crystalline forms of 3'-tert-butyl-3'-n-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-n-debenzoyl-4-o-methoxycarbonyl-paclitaxel processes for the production thereof; pharmaceutical compositions thereof; methods for preparing the pharmaceutical composition; and methods for inhibiting tumor growth therewith. ... 05/25/06 - 20060111432 - Paclitaxel aqueous injection solution and methods for preparing the same The present invention provides an injectable pharmaceutical composition containing, as an active ingredient, paclitaxel, an anti-cancer agent. The injectable pharmaceutical composition comprises an effective amount of paclitaxel, which is dissolved in polyoxyethylated castor oil, alcohol, and an injectable aqueous solution. A sufficient amount of CO2 is added to stabilize paclitaxel ... 05/18/06 - 20060106090 - Cytotoxic agents comprising taxanes and their therapeutic use A cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more taxanes covalently bonded to a cell binding agent through a linking group, and (B) a pharmaceutically acceptable carrier, diluent ... 05/11/06 - 20060100268 - Method of treating atherosclerosis or restenosis using microtube stabilizing agent The present invention is a method of preventing or reducing atherosclerosis or restenosis, and a pharmaceutical preparation used therefor. In particular, it is a method of preventing or reducing atherosclerosis or restenosis after arterial injury by treatment with a low dose of a microtubule stabilizing agent such as taxol or ... 04/13/06 - 20060079571 - Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel a synthon useful for the preparation of taxanes with antitumour activity, and intermediates for the preparation thereof. Also described is a process for the preparation of Docetaxel starting from the compound of formula (I). ... 03/30/06 - 20060069150 - Processes for preparation of crystalline mycophenolate sodium Provided are crystalline mycophenolate sodium forms and processes for their preparation. ... 02/16/06 - 20060035962 - Method and compositions for preparing a compound using a benzoylating agent essentially free of ring chlorination This invention relates to methods and compositions for preparing compounds using a benzoylating agent essentially free of ring chlorination. In one alternative embodiment, the present invention relates to methods and compositions for preparing taxanes essentially free of ring chlorinated impurities. In another alternative embodiment, the present invention comprises methods of ... 12/08/05 - 20050272807 - Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates. ... 12/08/05 - 20050272806 - Injectable formulations of taxanes for cad treatment Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed ... 12/01/05 - 20050267201 - Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same Pharmaceutical compositions for oral administration to mammalian subjects comprise a taxane or taxane derivative (e.g., paclitaxel or docetaxel) as active ingredient and a vehicle comprising at least 30% by weight of a carrier for the taxane, said carrier having an HLB value of at least about 10. The compositions may ... 11/10/05 - 20050250844 - Methods of treating cancer using c-4 carbonate taxanes A process for the preparation of novel C-4 carbonate taxanes useful as antitumor agents. ... 09/22/05 - 20050209311 - C7 lactyloxy-substituted taxanes wherein X3 is furyl, X5 is t-butoxycarbonyl, Bz is benzoyl, and Ac is acetyl. ... 09/22/05 - 20050209310 - Methods for modulating tumor growth and metastasis Methods and pharmaceutical compositions for modulating tumor growth or metastasis and methods for prognosing treatment therewith are provided. ... 09/08/05 - 20050197386 - Alkyl carbamate-substituted beta-lactones, process and intermediate products for their preparation, and pharmaceutical compositions containing them wherein R1, R2 and n have the meanings given in the specification, and pharmaceutical compositions which contain these compounds and have a pancreatic lipase-inhibiting action, as well as a process for the preparation of the compounds of Formula I and intermediate products of this process. ... 07/21/05 - 20050159477 - Stable amorphous calcium pseudomonate and processes for the preparation thereof The invention provides stable amorphous calcium pseudomonate. ... 07/07/05 - 20050148657 - 9, 10-alpha, alpha-oh-taxane analogs and methods for production thereof wherein R1 and R2 are each selected from H, an alkyl group, an olefinic group, an aromatic group, an O-alkyl group, an O-olefinic group, or an O-aromatic group; R3 is hydroxyl or OP,; R4 and R5 are each hydroxyl or R7COO; R6 is hydroxyl, OP2, R7COO, or an ether functionality; ... 06/30/05 - 20050143447 - C10 heterosubstituted acetate taxane compositions Compositions comprising a taxane having a heterosubstituted acetate substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents. ... 06/30/05 - 20050143446 - C7 heterosubstituted acetate taxane compositions Texanes having a heterosubstituted acetate substituent at C(7), a hydroxy substitutent at C(10), and a range of C(2), C(9), C(14), and side chain substituents. ... 06/16/05 - 20050131057 - Taxane chemosensitivity prediction test The present invention provides a method for determining the chemosensitivity of a cancer cell to a taxane comprising assessing the effect of the taxane on the expression level or activity of one or more cell cycle molecules in a cancer cell. Such a method makes use of an automated analyzer ... 06/02/05 - 20050119333 - Compositions comprising ether compounds and pharmaceutical uses therefor The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing ... ### FreshPatents.com Support |