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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai > Five-membered Hetero Ring Containing At Least One Nitrogen Ring Atom (e.g., 1,2,3-triazoles, Etc.) > The Five-membered Hetero Ring Consists Of One Nitrogen And Four Carbons > Polycyclo Ring System Having The Five-membered Hetero Ring As One Of The Cyclos

Polycyclo Ring System Having The Five-membered Hetero Ring As One Of The Cyclos

Polycyclo Ring System Having The Five-membered Hetero Ring As One Of The Cyclos patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/28/06 - 20060293378 - Method of lowering intraocular pressure
A method of lowering intraocular pressure and/or treating glaucoma comprises administering to a patient a therapeutically effective amount of a fused pyrrolocarbazole derivative, or a pharmaceutically acceptable salt or prodrug thereof. ...

11/02/06 - 20060247294 - Novel fused pyrrolocarbazoles
The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles. ...

10/26/06 - 20060241166 - Sapphyrins and uses thereof
The present invention relates to compounds of Formula (I): their pharmaceutical composition and their utility in treating neoplasm. ...

10/12/06 - 20060229352 - Intermediate compounds for the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1h-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole
processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole. ...

06/29/06 - 20060142370 - Sumanene and method for manufacturing the same
b) catalyst quantity of (PCy3)2RuCl2═CHPh, CH2═CH2, toluene, 0° C. to 80° C. c) DDQ, toluene, 110° C. ...

06/22/06 - 20060135590 - Selected fused pyrrolocarbazoles
The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles. ...

06/15/06 - 20060128780 - Cyclic substituted fused pyrrolocarbazoles and isoindolones
The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones. The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones. ...

06/08/06 - 20060122252 - Novel antituberculosis compounds, hirsutellones a, b, and c
Three new alkaloids, Hirsutellones A, B, and C, are produced in cultures of fungus such as Hirsutella nivea strain BCC 2594 and Trichoderma sp. strain BCC 7579. The Hirsutellones exhibited potent growth inhibitory activity against Mycobacterium tuberculosis (H37Ra strain) with an MIC value of 0.78 μg/ml, while showing weak or ...

06/01/06 - 20060116415 - Novel tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators
The present invention is directed to novel tetracyclic heteroatom containing derivatives, pharmaceutical compositions containing them, their use in the treatment of disorders mediated by one or more sex steroid hormone receptors and processes for their preparation. ...

05/25/06 - 20060111423 - Use of diindolylmethane-related indoles and growth factor receptor inhibitors for the treatment of human cytomegalovirus-associated disease
The present invention includes compositions and methods for the treatment and prevention of conditions associated with Human Cytomegalovirus (HCMV) infection. HCMV-associated conditions include infections (active and latent), benign cell-proliferative conditions, pre-cancerous cell-proliferative conditions, and cancerous conditions. In particular, the present invention describes new therapeutic and preventative uses for 3,3′-diindolylmethane (DIM), ...

05/11/06 - 20060100262 - Tetracyclic indole derivatives as antiviral agents
wherein R1, R2, A, Ar, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus. ...

04/20/06 - 20060084692 - Treatment of bipolar disorders and associated symptoms
or a pharmaceutically acceptable salt, solvate, hydrate or optical isomer thereof. ...

03/09/06 - 20060052433 - Compound
The present invention provides photosensitizing agents obtained by reducing a single double bond in the porphyrin macrocycle of a sulphonated meso-tetraphenylporphyrin, preferably a disulphonated meso-tetraphenylporphyrin such as TPPS2a. The resulting sulphonated meso-tetraphenyl chlorins include compounds of formula (I) (wherein X is —SO3H; n, p, q and r are each independently ...

02/16/06 - 20060035952 - Photosensitizer formulations and their use
A low concentration formulation for hydrophobic photosensitizers (PS) and improved method for photodynamic therapy (“PDT”). It was found that PDT treatments using the disclosed low concentration formulations provide for more accurate, more efficient and more convenient dosing. It was found that the inventive formulation (1) reduces the time for a ...

01/05/06 - 20060004080 - Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof a jnk inhibitors and compositions and methods related thereto
and pharmaceutically acceptable salts thereof, wherein Ro is —CH2—, —SO—, —O—, —SO2—, or —S—; compositions comprising the iazoloanthrones, isooxazoloanthrones, isoindolanthrones, and derivatives thereof; and methods for treating or preventing a disorder alleviated by inhibiting Jun N-terminal kinase (JNK) by administering the isaothiazoloanthrones, isooxazoloanthrones, isoindolanthrones, and derivatives thereof are described herein. ...

11/10/05 - 20050250834 - Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical composition containing them
The present invention relates to novel tetracyclic arylcarbonyl indoles, their derivatives, their analogues, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, novel intermediates described herein and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel tetracyclic arylcarbonyl indoles of the general ...

10/27/05 - 20050239863 - Novel maxi-k channel blockers, methods of use and process for making the same
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to ...

09/22/05 - 20050209299 - Inhibition of mixed lineage kinases and uses therefor
Provided herein are methods of using an inhibitor of an MLK protein or polypeptide to inhibit cell proliferation in neoplastic cells, such as for example, a cancer. Such methods may be used to treat a cancer and further may be used in conjunction with administration of an anticancer drug at ...

09/22/05 - 20050209298 - Method of photodynamic diagnosis for vascular diseases
Various diagnostics with the application of photodynamic diagnosis/therapy (photodynamic therapy: PDT) wherein use is made of highly selective uptake of an iminochlorinaspartic acid derivative or its pharmacologically acceptable salt in neovessels and selective uptake thereof in cancer cells. More specifically, remedies for rheumatism, remedies for inflammatory keratosis, agents for confirming ...

08/04/05 - 20050171182 - Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases
Methods for treating a subject suffering from a cellular proliferative disease characterized by the presence of a mutant receptor tyrosine kinase are provided. In practicing the subject methods, an effective amount of a CDK4 inhibitor, either alone or in combination with at least one of an inhibitor of the mutant ...



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