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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai > Five-membered Hetero Ring Containing At Least One Nitrogen Ring Atom (e.g., 1,2,3-triazoles, Etc.) > 1,3,4-thiadiazoles (including Hydrogenated) > Polycyclo Ring System Having The Thiazole Ring As One Of The Cyclos

Polycyclo Ring System Having The Thiazole Ring As One Of The Cyclos

Polycyclo Ring System Having The Thiazole Ring As One Of The Cyclos patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/28/06 - 20060293372 - Beta-sheet mimetics and methods relating to the use thereof
β-sheet mimetics and methods relating to the same are disclosed. The β-sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a β-sheet mimetic, or use of the same for the manufacture of ...

10/19/06 - 20060235060 - Hetero-polycyclic compounds, and coloring matters, pigments, dyes, color-changing material compositions, and color-changing films, made by using the compounds
Provided are novel hetero-polycyclic compounds having a specific structure, color-changing material compositions comprising (A) a fluorescent coloring matter comprising at least one of the hetero-polycyclic compounds described above and (B) a binder material, color-changing films comprising the above hetero-polycyclic compounds, coloring matters comprising the above hetero-polycyclic compounds, and pigments or ...

09/21/06 - 20060211747 - Methods of screening for compounds which inhibit the activity of cdc34 in a zinc-mediated manner and compounds obtained by this method
The present invention relates to methods of searching/screening for compounds which inhibit the activity of the ubiquitin conjugating enzyme Cdc34 in a zinc-mediated manner, to compounds obtainable by such a method, to a method of treating mammalian subjects with such compounds, to pharmaceutical compositions containing such compounds, to the use ...

07/27/06 - 20060167067 - Gm-95-containing antitumor effect potentiator, combined antitumor preparation and antitumor agent
wherein each R independently represents a hydrogen atom, a lower alkyl group, an aryl group, an allyl group, an aralkyl group, a halogen atom, a hydroxyl group, an amino group, R′O—, R′(C═O)—, R′(C═O)O—, or R′O(C═O)—, wherein R′ is an alkyl group containing 1 to 5 carbon atoms, or a pharmaceutically ...

06/29/06 - 20060142355 - Carboxylic acid peri-substituted bicyclics for occlusive artery disease
A representative example is: ...

05/11/06 - 20060100254 - Thiazolyl-dihydro-indazole
R1 to R3 are defined as in Claim 1, which are suitable for treating diseases which are characterized by excessive or anomalous cell proliferation, and their use for producing a pharmaceutical having the abovementioned properties. ...

01/05/06 - 20060004066 - Method for treating adamts-5-associated disease
The present invention relates to methods of treating ADAMTS-5-associated diseases and particularly osteoarthritis comprising administering an agent capable of modulating ADMATS-5 activity to a subject afflicted with the disease. The agent is preferably a biaryl sulfonamide compound. The invention is based, in part, on the discovery that transgenic animals that ...

12/22/05 - 20050282874 - Novel thiazolopyrazoles and methods of their use
This invention concerns novel thiazolopyrazole compounds and compositions comprising them. Methods of using these compounds for the treatment, prevention and management of various diseases and disorders are also encompassed by the invention. ...

12/15/05 - 20050277684 - Oxidative activation and episulfonium ion-mediated dna alkylation-based anticancer
The present invention relates to TG-25 and/or analogs thereof and their use of TG-25 in the treatment of cancer. TG-25 inhibits the growth of prostate cells by inhibiting DNA synthesis, more particularly by DNA cleavage. ...

11/17/05 - 20050256175 - Novel glucagon antagonists/inverse agonists
Novel compounds that act to antagonize the action of the glucagon peptide hormone on the glucagon receptor. More particularly, it relates to glucagon antagonists or inverse agonists. ...

10/06/05 - 20050222224 - P53 inhibitors and therapeutic use of the same
The therapeutic use of temporary p53 inhibitors in the treatment of p53-mediated diseases, conditions, and injuries is disclosed. ...

09/08/05 - 20050197365 - Diamino thiazoloindan derivatives and their use
wherein Y is O, NR3R4 or NOR6; R3 is H, alkyl, aralkyl, alkynyl, trifluoroacetyl, t-butoxycarbonyl or an acyl group; R4 is H, alkyl, aralkyl, or alkynyl; R6 is H or C1-C4 alkyl; R1 and R2 are each independently H, alkyl, aralkyl, or alkynyl; the curved line drawn from S to ...

07/07/05 - 20050148643 - Carbamate compositions and methods fo rmodulating the activity of the chk1 enzyme
Described herein are carbamate compounds. Such compounds are capable of modulating the activity of a checkpoint kinase, and described herein are methods for utilizing such modulation to treat cell proliferative disorders. Also described are pharmaceutical compositions containing such compounds. Also described are the therapeutic or prophylactic use of such compounds ...

07/07/05 - 20050148642 - Aminomethyl-substituted thiazolobenzimidazole derivative
Provided that R3 does not represent a lower alkyl or a halogeno-lower alkyl when X is a bond and n is 1. Also, R4 represents a group other than Me when m is 1, R1 is OH or OMe and Alk1 is a C1-3 alkylene, and further 1) when X ...

06/23/05 - 20050137237 - Triazolo-epothilones
The invention relates to triazolo-thiazole analogues of epothilone A and epothilone B. ...

06/02/05 - 20050119319 - Derivatives of azaspiro compounds for the treatment of pain
This invention relates to azaspiro compounds and their use as medications especially for the treatment of chronic, chronic-phlogistic and/or neuropathic pain. Compounds that lend themselves particularly well to the production of analgesics include 1,3-diazaspiro[4.5]decane-2,4-dion and 1,3-diazaspiro[4.5]decane-2,4-dithion. ...



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