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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai > Hetero Ring Is Six-membered Consisting Of One Nitrogen And Five Carbon Atoms > Polycyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos > Tricyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos

Tricyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos

Tricyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/28/06 - 20060293358 - Tyrosine kinase inhibitors
The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. ...

12/21/06 - 20060287351 - Antibiotic cycloalkyltetrahydroquinoline derivatives
A method of treating a subject for a bacterial infection includes administering to a subject in need of treatment for a bacterial infection an effective amount of a compound represented by structural formula (I), or a pharmaceutically acceptable salt, solvate, or hydrate thereof. The variables in structural formula (I) are ...

12/07/06 - 20060276495 - Treatment methods of nasal congestion and nasal obstruction
The use of desloratadine and/or other antihistamines for treating and/or preventing severe nasal congestion and/or nasal blockage associated with allergic and inflammatory conditions of the upper and lower airway passages in a human. ...

11/30/06 - 20060270697 - Treatment method
Methods of treating and/or preventing a cardiovascular disease in a human suffering from an allergic and/or inflammatory condition or cardiovascular disease by administrating an effective amount of loratadine, in combination with an effective amount of montelukast, for such treating and/or preventing are disclosed. ...

10/05/06 - 20060223841 - Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine
Provided are stable pharmaceutical compositions of desloratadine. Also provided are processes for preparing polymorphs of desloratadine ...

10/05/06 - 20060223840 - Substituted piperidine compounds and methods of their use
Certain 4-aryl-piperidine compounds, including N-substituted 9β-substituted-5-(3-substituted-phenyl)morphans and N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines, pharmaceutical compositions, and methods of their use, inter alia, as opioid antagonists are disclosed. ...

09/14/06 - 20060205755 - Novel farnesyl protein transferase inhibitors as antitumor agents
and the pharmaceutically acceptable salts thereof. Y is C or CH. When Y is C then Z is not present and the optional bond from Y to the C-11 carbon of the tricyclic nucleus is present. When Y is CH then Z is present and Z is H or —OH. ...

09/07/06 - 20060199831 - Injectable pharmaceutical compositions of an anthracenedione derivative with anti-tumoral activity
Injectable pharmaceutical compositions containing 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimalcate as active ingredient in the form of a lyophilised powder with a carrier selected from lactose and dextran, mixed with sodium chloride. ...

08/24/06 - 20060189641 - Novel 6-phenlyphenanthridines
in which R1, R2, R3, R31, R4, R5, R51, R6, R7 and R8 have the meanings indicated in the description, are novel effective PDE4 inhibitors. ...

08/17/06 - 20060183765 - Methods of treating cancer using an fpt inhibitor and antineoplastic agents
Disclosed is a method of treating cancer in a patient in need of such treatment comprising administering a therapeutically effective amount of an FPT inhibitor and therapeutically effective amounts of one or more antineoplastic agents. Methods of treating non small cell lung cancer, CML, AML, non-Hodgkin's lymphoma and multiple myeloma ...

07/20/06 - 20060160836 - Estrogen receptor structure
Estrogen receptor ligands, estrogen receptor polypeptide/ligand complexes, crystals of estrogen receptor polypeptide/ligand complexes, and related methods and software systems are disclosed. ...

07/13/06 - 20060154949 - Arylindenopyridines and related therapeutic and prophylactic methods
and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing Adensine A2a receptors or reducing PDE activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions. ...

07/13/06 - 20060154948 - Treating allergic and inflammatory conditions
The use of desloratadine for the preparation of a medicament for treating and/or preventing an allergic and inflammatory condition of the skin or upper and lower airway passages in a pediatric patient and a pediatric pharmaceutical composition effective for such treating and/or preventing which comprises an effective amount of desloratadine ...

06/29/06 - 20060142321 - 5-ht7 receptor antagonists
The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some some 2,2a,4,5-tetrahydro-1H-3-aza-acenaphthylen substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT ...

06/22/06 - 20060135547 - Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine
Provided are stable pharmaceutical compositions of desloratadine. Also provided are processes for preparing polymorphs of desloratadine ...

06/15/06 - 20060128738 - Treatment of interstitial cystitis using cannabinoid analogs
The present invention relates to non-psychoactive derivatives of tetrahydrocannabinol, which are useful in treating interstitial cystitis and relieving symptoms thereof. The invention uses cannabinol analogs, which are preferably analogs of (6aR,10aR)-Δ8-tetrahydrocannabinol-11-oic acids [hereinafter referred to as (6aR,10aR)-Δ8-THC-11-oic acid], as well as pharmaceutical compositions containing the cannabinol analogs and analogs of ...

06/15/06 - 20060128737 - Androgen receptor agonists
(R1, R2, X, Y, Z and m are as defined in claim 1) which show no excessive action on the prostate but show a particularly potent androgen receptor agonistic action on skeletal muscle tissue and bone tissue, as well as pharmaceuticals comprising such derivatives or their salts as active ingredients. ...

05/04/06 - 20060094742 - Prostaglandin ep4 antagonists
or pharmaceutically acceptable salts, or prodrugs thereof, which are antagonists of a prostaglandin EP4 receptor, or are prostaglandin EP4 antagonists. ...

03/23/06 - 20060063793 - Method of inhibiting neurotrophin-receptor binding
The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor to p75NTR comprises, particularly when bound to nerve growth factor, at least two ...

03/16/06 - 20060058334 - Preperation of desloratine
The present invention also provides a process for the preparation of substantially pure desloratadine by the process comprising acidic hydrolysis of a compound of formula 3 where R is selected from COR1, COOR1 wherein R1 is selected from branched or linear alkyl (1-6 C), cycloalkyl, alkenyl, alkynyl, aryl, aralkyl and ...

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// - 20 μl -
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01/12/06 - 20060009481 - Arylindenopyridines and related therapeutic and prophylactic methods
and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by reducing PDE activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions. ...

12/15/05 - 20050277660 - Novel tetrahydroquinoline derivatives
where R1, R2, X, Y and i are as defined in claim 1, which do not exhibit excessive action on the prostate, but which exhibit strong androgen receptor agonistic action particularly on skeletal muscle tissue and bone tissue, and pharmaceuticals comprising such derivatives or their salts as active ingredients. ...

12/01/05 - 20050267142 - Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions. ...

10/27/05 - 20050239812 - Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions. ...

10/20/05 - 20050234085 - Quinoline derivatives
The present invention relates to novel benzo [g] quinoline derivatives, their preparation, their use as pharmaceuticals for use in the treatment of glaucoma and myopia. ...

10/06/05 - 20050222190 - 1,4-bis-n-oxide azaanthracenediones and the use thereof
and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and p are as defined herein, for use in methods for treating, preventing or ameliorating hyperproliferative disorders, such as cancer. The invention also relates to pharmaceutical compositions and formulations comprising a compound having Formula IV, and in combination with one ...

10/06/05 - 20050222189 - Oxa-and thiadiazoles and their use as metalloproteinase inhibitors
Compounds formula (IA) or (IB), wherein W represents HO(C═O)—, HONH(C═O)— or H(C═O)N(OH)—; X represents —O— or —S—; and R1, R2, and R3 are as defined in the description and claims, are inhibitors of matrix metalloproteinases, in particular MMP9 and/or MMP12. ...

09/15/05 - 20050203117 - Treating allergic and inflammatory conditions
Methods of using desloratadine for substantially returning work-related performance and workplace productivity of a person suffering from an allergic and/or inflammatory condition of the skin airway passages, e.g., season allergic rhinitis, pernninal allergic rhinitis, atopic dermatitis, urticaria or allergic asthma to the person's baseline work-related or baseline workplace productivity are ...

09/15/05 - 20050203116 - Desloratadine salts,process for their synthesis and pharmaceutical compositions thereof
The object of the present invention are new desloratadine salts of formula I wherein the meaning of X is an acid residue and the meaning of n is 1 or 2, and formula II wherein the meaning of X is a pK<3.5 acid residue. The invention is related to a ...

07/28/05 - 20050165041 - Combination for the treatment of airway disorders
The invention relates to the combination of proton pump inhibitors and airway therapeutics for the treatment of airway disorders. ...



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