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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai > Hetero Ring Is Seven-membered Consisting Of One Nitrogen And Six Carbons > Chalcogen Double Bonded Directly To A Ring Carbon Of The Seven-membered Hetero Ring Which Is Adjacent To The Ring Nitrogen > Polycyclo Ring System Having The Seven-membered Hetero Ring As One Of The Cyclos > Plural Ring Hetero Atoms In The Polycyclo Ring System Plural Ring Hetero Atoms In The Polycyclo Ring SystemPlural Ring Hetero Atoms In The Polycyclo Ring System patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.12/28/06 - 20060293305 - Preparation of hymenialdisine derivatives and use thereof The synthesis and biological activity of indoloazepines and acid amine salts thereof which are structurally related to naturally-occurring hymenialdisine is disclosed. Naturally-occurring hymenialdisine obtained from the sponge is a potent inhibitor of production of cytokines interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α). The chemically-synthesized indoloazepines of the invention also inhibit ... 12/21/06 - 20060287296 - Preparation of hymenialdsine derivatives and use thereof The synthesis and biological activity of indoloazepines and acid amine salts thereof which are structurally related to naturally-occurring hymenialdisine is disclosed. Naturally-occurring hymenialdisine obtained from the sponge is a potent inhibitor of production of cytokines interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α). The chemically-synthesized indoloazepines of the invention also inhibit ... 12/07/06 - 20060276451 - Preparation of hymenialdisine derivatives and use thereof The synthesis and biological activity of indoloazepines and acid amine salts thereof which are structurally related to naturally-occurring hymenialdisine is disclosed. Naturally-occurring hymenialdisine obtained from the sponge is a potent inhibitor of production of cytokines interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α). The chemically-synthesized indoloazepines of the invention also inhibit ... 10/19/06 - 20060234997 - Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia are disclosed, wherein G, D, A, Q, Y, Z, and R1 through R10 are defined in the specification. Also provided are descriptions of processes for preparing compounds of formula 1, intermediates used in making the same, and pharmaceutical compositions containing such compounds and their use in the treatment of central ... 09/28/06 - 20060217368 - Drug for nerve regeneration An object of the present invention is to provide a nerve regenerating drug, an agent for the promotion of neuropoiesis of a neural stem cell, a neuron obtained by culturing a neural stem cell in the presence of the agent for the promotion of neuropoiesis, and a method of the ... 06/29/06 - 20060142266 - Compounds and their uses This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP. ... 04/06/06 - 20060074073 - Therapeutic combinations comprising poly (adp-ribose) polymerases inhibitor This invention provides pharmaceutical combinations of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, or a pharmaceutically acceptable salt thereof and at least one additional therapeutic agent, kits containing such combinations and methods of using such combinations to treat subjects suffering from diseases such as cancer. ... 07/07/05 - 20050148575 - Compounds and their uses This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP. ... 06/30/05 - 20050143370 - Therapeutic compounds The invention relates to trycyclic lactam indole derivatives and triacyclic lactam benzimodole derivatives and their use in inhibiting the activity of PARP enzyme. The invention also relates to the use of these compounds in the preparation of medicaments. ... ### FreshPatents.com Support |