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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai > Hetero Ring Contains Seven Members Including Nitrogen, Carbon And Chalcogen > Polycyclo Ring System Which Contains The Seven-membered Hetero Ring As One Of The Cyclos

Polycyclo Ring System Which Contains The Seven-membered Hetero Ring As One Of The Cyclos

Polycyclo Ring System Which Contains The Seven-membered Hetero Ring As One Of The Cyclos patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

01/18/07 - 20070015745 - Cyclohexyl(alkyl)propanolamines, preparation method and pharmaceutical compositions containing same
in which R represents a hydrogen or halogen atom, an —S(O)z(C1-C4)alkyl group, an —NHSO2(C1-C4)alkyl group, an —SO2NH(C1-C4)alkyl group, an —NHSO2phenyl-(C1-C4)alkyl group or an —NHSO2phenyl group, said phenyl possibly being substituted with a halogen atom, with a (C1-C4)alkyl group or with a (C1-C4)alkoxy group; R1 represents a hydrogen atom or a ...

07/27/06 - 20060166964 - Inhibitors of hcv replication
Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds. ...

07/20/06 - 20060160789 - Use of pharmacological compounds for the prevention or treatment of acute tolerance to morphines
or its pharmaceutically acceptable salts, for the preparation of a medicament intended for the prevention or treatment of acute tolerance to morphines or hyperalgesia caused by morphines, in an individual having received an administration of a morphine analgesic. ...

06/15/06 - 20060128687 - Lactam glycogen phosphorylase inhibitors and method of use
R1, R2, R3, R4, R5, R6, R7 and R8 are as described herein. Further provided is a method for treating diabetes and related diseases employing a glycogen phosphorylase inhibiting amount of the above compound, either alone or in combination with another therapeutic agent. ...

05/18/06 - 20060106007 - Hiv integrase inhibitors: cyclic pyrimidinone compounds
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating ...

03/23/06 - 20060063753 - Use of nefopam for the treatment of nausea or emesis
The invention relates to the use of nefopam for the manufacture of a medicament for the treatment of nausea, dizziness, blurred vision and emesis. ...

03/02/06 - 20060046983 - Inhibitors of hcv replication
Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds. ...

02/23/06 - 20060040917 - Benzoxazepine derivatives as selective estrogen receptor modulators
The present invention is directed to novel benzoxazepine derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and diseases mediated by an estrogen receptor. ...

02/16/06 - 20060035883 - Novel serotonin receptor ligands and their uses thereof
wherein X is —CH or —N—. Y is selected from the group consisting of —CR10R11, —NR12, —O—, —S—, —SO—, and —SO2—. R1 to R12 are various substituents selected to optimize the physicochemical and biological properties such as receptor binding, receptor selectivity, tissue penetration, lipophilicity, toxicity, bioavailability, and pharmacokinetics of compounds ...

02/16/06 - 20060035882 - Condensed benzamide compounds and inhibitors of vanilloid receptor subtype 1 (vr1) activity
To provide a compound having an excellent inhibitory effect on vanilloid receptor subtype 1 (VR1) activity which is effective in treating diseases to which the vanilloid receptor subtype 1 (VR1) activity is involved, such as pain, acute pain, chronic pain, neuropathic pain, rheumatoid arthritis pain, neuralgia, etc. and a pharmaceutical ...

10/06/05 - 20050222120 - Peptides derivatives comprising thiazepine group for the treatment of hyperlipidermic conditions
The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Process for their manufacture and pharmaceutical compositions containing ...

09/29/05 - 20050215540 - Novel anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (ryr2) and uses thereof
The present invention provides methods for limiting or preventing a decrease in the level of RyR2-bound FKBP12.6 in a subject. The present invention further provides methods for treating and preventing atrial and ventricular cardiac arrhythmias, heart failure, and exercise-induced sudden cardiac death in a subject. Additionally, the present invention provides ...

08/04/05 - 20050171087 - Non-steroidal progesterone receptor modulators
The present invention provides compounds according to general Formula (I), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt of a prodrug thereof. More particularly, the present invention provides high affinity non-steroidal compounds which are agonists, partial agonists or antagonists of the progesterone receptor. ...

06/30/05 - 20050143369 - Gamma-secretase inhibitors
inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease. ...



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