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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Cyclopentanohydrophenanthrene Ring System Doai > Hetero Ring Containing > Spiro Ring System

Spiro Ring System

Spiro Ring System patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

11/23/06 - 20060264412 - Steroid spirolactonization
A steroid comprising a 17-spirolactone or corresponding open lactone structure is obtained by carbonylation of a 17-alkenyl or 17-alkynyl substrate. A 17-alkenyl intermediate may be prepared by semi-hydrogenation of a 17-alkynyl group. Multiple reaction schemes are disclosed for preparation of a 3-keto-9,11-epoxy-17-spirolactone steroid such as eplerenone. Novel intermediates are also ...

11/09/06 - 20060252737 - 18-methyl-19-nor-17-pregn-4-ene-21,17-carbolactones, as well as pharmaceutical preparations that contain the latter
R6 and R7 together mean an α- or β-position methylene group or an additional bond. The new compounds have gestagenic and anti-mineralocorticoid action and are suitable for the production of pharmaceutical preparations, for example for oral contraception and the treatment of pre-, peri- and post-menopausal symptoms. ...

07/27/06 - 20060166952 - 2oxo-voruscharin and derivatives thereof
2″oxo-voruscharin compound and derivatives thereof are disclosed as well as pharmaceutical compositions which include 2″oxo-voruscharin compound or derivatives thereof. The disclosed 2″oxo-voruscharin compound and its derivatives are useful for cancer treatment. Methods of treating cancer using the disclosed compounds are also disclosed. ...

05/11/06 - 20060100185 - 5-androsten-3beta-ol steroid intermediates and processes for their preparation
The present invention provides 5-androsten-3β-ol steroid intermediates and processes for their preparation. ...

11/24/05 - 20050261261 - Eplerenone drug substance having high phase purity
A novel crystalline form (Form L) of the aldosterone receptor antagonist drug eplerenone is provided having relatively high physical stability at normal temperatures of storage and use. Pharmaceutical compositions are also provided comprising Form L eplerenone, optionally accompanied by one or more other solid state forms of eplerenone, in a ...

10/27/05 - 20050239761 - Processes for preparation of 9,11-epoxy steroids and intermediates useful therein
wherein -A-A-, —B—B—, R1, R3, R8 and R9 are as defined in the specification. ...

06/16/05 - 20050130948 - Therapeutic methods and uses of sapogenins and their derivatives
The invention discloses therapeutic methods and uses of certain steroidal sapogenins, related compounds and derivatives thereof, in the treatment of non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, motor-sensory neurodegeneration or receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment. ...



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