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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Acyclic Nitrogen Double Bonded To Acyclic Nitrogen, Acyclic Nitrogen Triple Bonded To Acyclic Nitrogen Or Azide Doai > 3,10-dihydroxy-2-naphthacene Carboxamide Or Derivative (e.g., Tetracycline, Etc.) Doai 3,10-dihydroxy-2-naphthacene Carboxamide Or Derivative (e.g., Tetracycline, Etc.) Doai3,10-dihydroxy-2-naphthacene Carboxamide Or Derivative (e.g., Tetracycline, Etc.) Doai patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.01/18/07 - 20070015739 - Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores The invention relates to a method for inhibiting bacterial spores from becoming infectious vegetative cells in a mammal in need thereof. In another embodiment, invention relates to a method for inhibiting outgrowth of bacterial spores in a mammal in need thereof. The method comprises administering to the mammal an effective ... 01/18/07 - 20070015738 - Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores from becoming infectious vegetative cells The invention relates to a method for inhibiting bacterial spores from becoming infectious vegetative cells in a mammal in need thereof. The method comprises administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. In one embodiment, the non-antibacterial tetracycline formulation comprises an antibacterial tetracycline in a sub-antibacterial ... 01/11/07 - 20070010498 - Method for reducing blood loss associated with cardio-pulmonary bypass surgery The invention provides a method for reducing blood loss associated with cardio-pulmonary bypass surgery in a human that is about to undergo, is undergoing, or has undergone, cardio-pulmonary bypass surgery. The method comprises administering to the human an effective amount of a non-antibacterial tetracycline formulation. The non-antibacterial tetracycline formulation is ... 01/04/07 - 20070004685 - Inhibition of thrombin generation The present invention is a method for inhibiting undesirable thrombin generation in a mammal in need thereof. The method comprises administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. ... 12/28/06 - 20060293290 - Method for the treatment of acne A method for treatment of acne with tetracyclines is provided. A lower sustained dose and no loading dose is employed, with an optional once-a-day dosing regimen. ... 12/21/06 - 20060287283 - Prodrugs of 9-aminomethyl tetracycline compounds The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them. ... 12/14/06 - 20060281717 - 11a, 12-derivatives of tetracycline compounds 11a, 12-dehydrotetracycline compounds are described. ... 11/09/06 - 20060252731 - Methods of treating recurrent aphthous stomatitis A method of treating recurrent aphthous stomatitis in a human in need thereof. The method comprises administering a tetracycline compound in an amount that is effective to treat recurrent aphthous stomatitis, but has substantially no antibacterial activity, without administering a bisphosphonate compound. ... 10/19/06 - 20060234988 - 7-n-substituted phenyl tetracycline compounds 7-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described. ... 10/12/06 - 20060229282 - 7, 8 and 9-substituted tetracycline compounds 7, 8 and 9-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7, 8 and 9-substituted tetracycline compounds are described. ... 09/14/06 - 20060205698 - 7-phenyl-substituted tetracycline compounds 7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. 7-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds ... 08/31/06 - 20060194773 - Tetracyline compounds having target therapeutic activities Methods and compounds for treating diseases with tetracycline compounds having a target therapeutic activity are described. ... 08/17/06 - 20060183720 - 9-substituted tetracyclines or a tautomer or pharmaceutically acceptable salts thereof useful as antibacterial agents. ... 08/17/06 - 20060183719 - Tetracycline metal complex in a solid dosage form with the proviso that if R2 is CH3 and R3 is H, then R4 is not OH. ... 08/03/06 - 20060172982 - Formulation comprising tetracycline or derivative and method of treating or preventing infections and inflammatory conditions Therapeutic composition and method for treating or preventing various conditions and diseases, including inflammatory conditions, allergies, particularly seasonal allergies, and the common cold. In a preferred embodiment, the therapeutic composition is a formulation comprising an antibiotic, preferably a tetracycline, most preferably doxycycline, which has not been chemically modified to eliminate ... 07/27/06 - 20060166946 - Methods of preparing substituted tetracyclines with transition metal-based chemistries The present invention relates to novel chemistries which allow for heretofore unobtainable substituted tetracycline compounds which exhibit significant antibacterial activity. The methods disclosed herein utilize reactive tetracycline-based precursor compounds, reactive organic substituent precursors and transition metal catalysts under conditions such that a tetracycline compound substituted with the desired organic substituent ... 07/27/06 - 20060166945 - Substituted tetracycline compounds The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression. ... 07/27/06 - 20060166944 - 4-aminotetracyclines and methods of use thereof The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression. ... 07/13/06 - 20060154901 - Methods for treating ocular rosacea A method for treating a patient having meibomian gland disease, ocular irritation associated with delayed tear clearance, or recurrent corneal epithelial erosion, is disclosed. Preferably, the method concerns treatment of a patient with topical tetracycline, a derivative or analogue of tetracycline, or a chemically modified tetracycline (CMT). Oral administration of ... 07/06/06 - 20060148766 - Composition comprising minocycline as an effective component for prevention and treatment of dementia, and learning and memory impairments The present invention relates to a composition for preventing and treating dementia and memory impairment, which contains minocycline as active ingredient. The composition of the present invention has an effect of inhibiting brain cell death and memory impairment, which are induced by amyloid beta-protein and C-terminal protein. Thus, the composition ... 07/06/06 - 20060148765 - 7-substituted fused ring tetracycline compounds 7-substituted fused ring tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds are described. ... 06/15/06 - 20060128675 - Method for monitoring the effectiveness of teracycline in the treatment of asthma The present invention is directed to a method of lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic which method comprises administering to said mammal an IgE lowering effective amount of a tetracycline such as minocycline or doxycline. It is also directed to a ... 05/18/06 - 20060106002 - Therapeutic agent for steroid depending-and/or steroid resistant- ulcerative colitis The present invention is directed to a pharmaceutical composition for the treatment of steroid depending and/or steroid resistive ulcerative colitis. The pharmaceutical composition, which is administered to treat steroid depending and/or steroid resistive ulcerative colitis, contains, as the active ingredients, at least one compound selected from a group consisting of ... 05/04/06 - 20060094697 - Methods of simultaneously treating ocular rosacea and acne rosacea A method for simultaneously treating ocular rosacea and acne rosacea in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat ocular rosacea and acne rosacea but has substantially no antibiotic activity. ... 04/27/06 - 20060089336 - 4-dedimethylamino tetracycline compounds The present invention pertains, at least in part, to novel substituted 4-dedimethylamino tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux ... 04/20/06 - 20060084634 - 7-pyrollyl tetracycline compounds and methods of use thereof A compound of Formula (I): ... 04/20/06 - 20060084633 - Formulations for treating or preventing mucositis Mucositis is treated and/or prevented by administrating to a patient a formulation comprising a tetracycline that is poorly absorbed from the gastro-intestinal tract. The tetracycline may be in the form of a pharmaceutically acceptable salt or a base. The formulations may optionally also contain an antifungal agent to prevent fungal ... 01/05/06 - 20060003971 - Aromatic a-ring derivatives of tetracycline compounds Aromatized A-ring derivatives of tetracycline compounds are described. ... 12/29/05 - 20050288262 - 3, 10, and 12a substituted tetracycline compounds The present invention pertains to novel 3, 10, and/or 12a-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation ... 12/22/05 - 20050282787 - Synthesis of tetracyclines and analogues thereof The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines ... 12/22/05 - 20050282786 - Method for reducing c-rective protein levels with non-antibacterial tetracycline formulations The present invention is for a method for decreasing C-reactive protein levels (CRP) in a mammal in need thereof. The method comprises administering an effective amount of a non-antibacterial tetracycline formulation, to the mammal. In one embodiment, the non-antibacterial tetracycline formulation is a non-antibacterial amount of an antibacterial tetracycline. In ... 12/15/05 - 20050277623 - Treatment for averting or delaying premature delivery The present invention relates to a method for averting or delaying premature delivery of mammalian infants. This method includes administering to a pregnant mammalian female an agent which interferes with degradation of cervical and/or fetal membrane connective tissue elements under conditions effective to avert or delay premature delivery of an ... 12/01/05 - 20050267079 - Tetracycline derivatives and methods of use thereof A treatment for inhibiting microbial or tumor growth is disclosed, which comprises adding to a subject in need of treatment an effective amount of one or more tetracycline derivatives. ... 11/10/05 - 20050250744 - Pharmaceutically active compounds and methods of use thereof The invention includes new substituted tetracycline-type compounds that exhibit significant antibacterial activity, including against both gram-positive and gram-negative bacteria. It has been found that compounds of the invention are highly active against both gram positive and gram negative tetracycline sensitive and tetracycline resistant bacteria. ... 09/29/05 - 20050215532 - Tetracycline compounds for treatment of cryptosporidium parvum related disorders Methods and compositions for treating Cryptosporidium parvum related disorders in a mammal are discussed. Several novel tetracycline compounds useful for treating Cryptosporidium parvum related disorders are also included. ... 09/22/05 - 20050209202 - Methods of treating rosacea A method of treating rosacea in a human in need thereof comprising administering to said human a tetracycline compound in an amount that is effective to treat rosacea, but has substantially no antibiotic activity. ... 08/25/05 - 20050187198 - Methods of preparing substituted tetracyclines with transition metal-based chemistries The present invention relates to novel chemistries which allow for heretofore unobtainable substituted tetracycline compounds which exhibit significant activity in tetracycline responsive states. The methods disclosed herein utilize reactive tetracycline-based precursor compounds, reactive organic substituent precursors and transition metal catalysts under conditions such that a tetracycline compound substituted with the ... 08/04/05 - 20050171068 - Novel 4-dedimethylaminotetracycline derivatives The present invention provides new chemically modified 4-dedimethylaminotetracycline compounds that can be substituted with aryl, alkenyl, or alkynyl groups. The 7, 8, and/or 9 positions and methods for preparing such compounds. Other tetracycline compounds include the 4-dedimethylaminotetracycline derivatives with an oxime group, NH-Alkyl, or N—NH-Alkyl group substituted at the C4 ... 07/28/05 - 20050164993 - Methods of treating allergic reactions A method for treating an allergic reaction other than asthma in a mammal need thereof comprising administering to said mammal a tetracycline compound in an amount that is effective to treat said allergic reaction. ... 07/14/05 - 20050153944 - Oxazole derivatives of tetracyclines wherein A″, X and Y are defined in the specification. These compounds are useful as antibacterial agents. ... 07/14/05 - 20050153943 - Methods of simultaneously treating mucositis and fungal infection A method for simultaneously treating mucositis and fungal infection in a mammal in need thereof, said method comprising administering to said mammal an effective amount of an anti-mucositis and anti-fungal pharmaceutical composition consisting of a tetracycline compound in an amount that is effective to simultaneously treat mucositis and fungal infection, ... 07/07/05 - 20050148552 - Methods of treating eczema A method of treating eczema in a human or other mammal in need thereof comprising administering systemically to said human or other mammal a tetracycline compound in an amount that is effective to treat eczema, but has substantially no antibacterial activity. ... 07/07/05 - 20050148551 - 7, 8 and 9-substituted tetracycline compounds 7, 8 and 9-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7, 8 and 9-substituted tetracycline compounds are described. ... 06/30/05 - 20050143353 - 13-substituted methacycline compounds 13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described. ... 06/30/05 - 20050143352 - Substituted tetracycline compounds The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression. ... 06/23/05 - 20050137174 - Prodrugs of 9-aminomethyl tetracycline compounds The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them. ... 06/02/05 - 20050119235 - 7-phenyl-substituted tetracycline compounds 7-phenyl-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. ... ### FreshPatents.com Support |