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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Phosphorus Containing Other Than Solely As Part Of An Inorganic Ion In An Addition Salt Doai > Two Or More Phosphorus Atoms Directly Or Indirectly Bonded Together By Only Covalent Bonds Two Or More Phosphorus Atoms Directly Or Indirectly Bonded Together By Only Covalent BondsTwo Or More Phosphorus Atoms Directly Or Indirectly Bonded Together By Only Covalent Bonds patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.01/18/07 - 20070015736 - Pharmaceutical products comprising bisphosphonates A pharmaceutical product comprises a container containing a bisphosphonate solution, in which at least the internal surface of the container comprises a plastic material and in which the container is heat sterilisable, and which is in the form of a ready to use infusion solution, for administration of the bisphosphonate ... 11/16/06 - 20060258626 - Use of inositol-tripyrophosphate in treating tumors and diseases Inositol-tripyrophosphate is an allosteric effector of hemoglobin due to its ability to cross the plasma membrane of red blood cells and deliver oxygen to solid tumors, by lowering the oxygen affinity of the hemoglobin of red blood cells. The present invention is directed to the use of inositol-tripyrophosphate to reduce ... 10/26/06 - 20060241086 - Calcium salt of myo-inositol 1,6:2,3:4,5 tripyrophosphate as an allosteric effector of hemoglobin The present invention relates to various salts of inositol tripyrophosphate including the calcium, lithium, beryllium, magnesium, potassium, strontium, barium, rubidium and cesium salts of inositol tripyrophosphate, compositions comprising these salts, methods of making the various salts, and methods of use of the above salts. Methods of use include administering the ... 09/28/06 - 20060217350 - Disodium pamidronate formulation A stable pharmaceutical composition comprising a solution of disodium pamidronate in an aqueous solvent and a process for the preparation thereof. The solution of disodium pamidronate is free of particulate matter and has an alkaline pH. The process for preparation of the stable pharmaceutical composition comprises adding disodium pamidronate and ... 08/03/06 - 20060172976 - Ibandronate polymorph The present invention relates to a new crystalline polymorph of 3-(N-methyl-N-pentyl) amino-1-hydroxypropane -1,1-diphosphonic acid monosodium salt monohydrate (Ibandronate) with the following formula ... 08/03/06 - 20060172975 - Ibandronate polymorph The present invention relates to a new polymorph crystal form of 3-(N-methyl-N-pentyl)amino-1-hydroxypropane-1 1-diphosphonic acid monosodium salt monohydrate (Ibandronate) with the following formula ... 07/20/06 - 20060160774 - Oxathiazaphospholidine free radical control agent wherein R2 represents a moiety selected from the group consisting of alkyl groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, and alkaryl groups; wherein the alky groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, and alkaryl groups can be substituted, unsubstituted, linear, branched or cyclic; and wherein Ar ... 07/13/06 - 20060154900 - Diphosphonate solutions A pharmaceutical product containing pamidronate and other diphosphonate solutions in an appropriate container, a pH of between 5 and 8 and without organic acid buffer or polyethylen glycol. The container may be treated glass or made of other appropriate material. Coated elastomeric stoppers are also included. A method of producing ... 06/01/06 - 20060116358 - Inositol pyrophosphates, and methods of use thereof The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to ... 05/18/06 - 20060106001 - Novel phytic citrate compounds and process for preparing the same wherein said R is H or citrate and wherein at least one R is citrate. The salt of the chemical compound is the Na+, K+, Mg2+, or Ca2+ salt of said chemical compound. The chemical compound is a chelator which chelates sodium, potassium or lithium, magnesium, calcium, copper, iron, lead, ... 05/18/06 - 20060106000 - Use of inositol-tripyrophosphate in treating tumors and diseases Inositol-tripyrophosphate is an allosteric effector of hemoglobin due to its ability to cross the plasma membrane of red blood cells and deliver oxygen to solid tumors, by lowering the oxygen affinity of the hemoglobin of red blood cells. The present invention is directed to the use of inositol-tripyrophosphate to reduce ... 04/13/06 - 20060079488 - Methods of treating and preventing bone loss Methods of treating and preventing bone loss and/or enhancing bone formation are disclosed. The methods utilize 15-lipoxygenase inhibitors. These molecules can be delivered alone or in combination with agents which inhibit bone resorption or additional agents that regulate calcium resorption from bone or enhances bone accumulation. The invention additionally provides ... 03/02/06 - 20060046982 - Orthomolecular medical use of l-citrulline for capillary endothelial protection and adjacent cell protection in neurodegenerative disease This invention embodies use of exogenous L-citrulline not only for support of capillary endothelial function, by L-citrulline bioconversion to plasma L-arginine to provide more cell substrate for enzymatic generation of nitric oxide, but also for providing more L-arginine in cellular microenvironments including that in acidified endosomes and lysosomes for potential ... 02/16/06 - 20060035867 - Methods of treating cancer and the pain associated therewith using endothelin antagonists The instant invention is directed to methods for the inhibition of bone metastases, methods for the prevention of growth of new metastases, methods for the inhibition of bone turnover, and methods for the prevention of bone loss in patients, including cancer patients, using an endothelin ET-A receptor antagonist. ... 02/16/06 - 20060035866 - Phosphonate compounds having immuno-modulatory activity The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds. ... 12/22/05 - 20050282784 - Therapy using a combination of raloxifene and alendronate Provided are methods of treating bone disease including, but not limited to, osteoporosis, metastatic bone disease, or Paget's disease, by administering a combination of raloxifene and alendronate in a manner that mitigates the formation of ulcerative adverse events. ... 12/08/05 - 20050272707 - Method for preventing or reducing secondary fractures after hip fracture Use of a bisphosphonate in the preparation of a medicament for the treatment of osteoporosis post hip fracture to prevent or reduce subsequent osteoporotic skeletal fractures in a patient in need of such treatment, and particularly to a patient who has undergone recent repair of the hip fracture and corresponding ... 12/01/05 - 20050267075 - Sulfonylethyl phosphorodiamidates Sulfonylethyl and thioethyl phosphorodiamidates, their preparation and intermediates in their preparation, formulations containing them, and their pharmaceutical use. The compounds are useful for treating cancer, alone and in combination with other anticancer therapies. ... 11/10/05 - 20050250743 - Ammonium salts of inositol hexaphosphate, and uses thereof The present invention comprises compounds, compositions thereof, and methods capable of delivering inositol hexaphospahte (IHP) to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to ... 09/29/05 - 20050215529 - Method of treating oxidative stress-associated conditions with isopentenyl diphosphate It has been found that isopentenyl diphosphate possesses antioxidant effects 1000 to 10,000 times more potent than classical antioxidants, such as ascorbic acid, β-carotene, and α-tocopherol, and 100 times more potent than 2-chloroadenosine. With such high potency, as disclosed herein, isopentenyl diphosphate can be used to treat or prevent one ... 09/22/05 - 20050209198 - Pharmaceutical composition comprising a bisphosphonate and a cox-2 inhibitor for the treatment of bone diseases A pharmaceutical composition for treatment of conditions of abnormal bone turnover, comprises in combination a bisphosphonate and a COX-2 inhibitor for simultaneous, sequential or separate use. Also provided is a method of treating a patient suffering from a condition involving abnormal bone turnover, comprising administering to the patient an effective ... 09/22/05 - 20050209197 - Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease. ... 08/25/05 - 20050187195 - Inhibition of intestinal apical membrane na/phosphate co-transportation in humans The compounds of formula (I) are hydrophilic aryl phosphate, thiophosphate, and aminophosphate intestinal apical membrane Na-mediated phosphate co-transportation inhibitors. The compounds can be administered orally, where they act to inhibit Na-dependent phosphate uptake in the intestines, or internally, where they interact with the phosphate control functions of the kidneys and ... 08/18/05 - 20050182030 - Liquid injectable formulation of disodium pamidronate The present invention relates to an improved injectable ready-to-use preparation of pamidronate salts, methods for its manufacture and uses of the solution of the invention in the manufacture of pharmaceutical compositions for the treatment of diseases selected from the group of tumour-induced hypercalcaemia, Paget's disease, osteoporosis, bone metastases, or breast ... 08/04/05 - 20050171063 - Use of phosphono derivatives as anti-malarials The invention provides the use of phosphono derivatives of selected aliphatic acids represented by the structural formulae R—COOH, R being PO3H2 or CR1R2—PO3H2 where R1/R2 are H, OH, COOH or alkyl groups for the treatment of malaria. The use of the compound comprises administering an effective amount of said compounds ... 07/14/05 - 20050153938 - Polyphosphonate derivatives for toothpaste compositions The invention relates to a medicament containing the polyphosphonate compound of general formula (I) as an active ingredient. ... ### FreshPatents.com Support |