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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > Phosphorus Containing Other Than Solely As Part Of An Inorganic Ion In An Addition Salt Doai > Nitrogen Containing Hetero Ring > Hetero Ring Is Six-membered Consisting Of Two Nitrogens And Four Carbons

Hetero Ring Is Six-membered Consisting Of Two Nitrogens And Four Carbons

Hetero Ring Is Six-membered Consisting Of Two Nitrogens And Four Carbons patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

02/01/07 - 20070027115 - Triazole derivatives useful in therapy
The compounds of the invention are useful in the treatment of fungal infections, and have good aqueous solubility. ...

01/18/07 - 20070015733 - Aryl phosphate derivatives of d4t having activity against resistant hiv strains
Methods of inhibiting virus replication of in a cell infected with a resistant strain of HIV that includes administering to the infected cell a virus replication inhibiting amount of an aryl phosphate derivative of d4T. ...

12/28/06 - 20060293285 - Aryl phosphate derivatives of d4t
Specific aryl phosphate nucleoside derivatives show activity against HIV without undesirable levels of cytotoxic activity. In particular, these derivatives are potent inhibitors of HIV reverse transcriptase. Examples of aryl phosphate nucleoside derivatives include aryl phosphate derivatives of d4T having one or more substituents on the aryl group, and wherein the ...

12/14/06 - 20060281712 - Pyrimidine compounds
This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the ...

12/14/06 - 20060281711 - Il-12 modulatory compounds
The invention relates to cyclic hydrazone compounds, compositions including the cyclic hydrazone compounds and methods of using and methods of making thereof. The compounds (and compositions) are useful, inter alia, in modulating IL-12 production and processes mediated by IL-12. ...

11/23/06 - 20060264406 - Mono-lysine salts of azole compounds
wherein A in formula I represents the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group. R and R1 in formula I can each be a hydrogen atom or an alkyl group having one to six carbon atoms. The novel water-soluble azole ...

10/26/06 - 20060241081 - Novel compounds and methods for therapy
R1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I). ...

09/07/06 - 20060199786 - Process and methods for the preparation of optically active cis-2-hydroxymethyl-4- (cytosin-1'-yl) -1,3-oxathiolane or pharmaceutically acceptable salts thereof
wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts. ...

08/10/06 - 20060178346 - Imines as ion channel modulators
The present invention provides a class of chemical compounds useful in the treatment of sickle cell disease, diseases characterized by unwanted or abnormal cell proliferation and for the treatment of ocular disorders such as glaucoma. The active compounds are tri-(aryl or heteroaryl) methane compounds or analogues thereof which further comprise ...

07/27/06 - 20060166936 - Diaminotriazole compounds useful as inhibitors of protein kinases
The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention, processes for preparing the compounds and methods of using the compositions in the treatment of various disorders. ...

09/29/05 - 20050215527 - Antiviral activity and resolution of 2-hydroxymethyl-5- (5-fluorocytosin-1-yl)-1, 3-oxathiolane
A method and composition for the treatment of HIV and HBV infections in humans is disclosed that includes administering an effective amount of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane, a pharmaceutically acceptable derivative thereof, including a 5′ or N4 alkylated or acylated derivative, or a pharmaceutically acceptable salt thereof, in a pharmaceutically acceptable carrier. A ...

09/29/05 - 20050215526 - Melanin concentrating hormone receptor antagonist
wherein A, W, X, Z, R1-R3, and R8 are as defined in the specification, are provided. Also provided are methods of treating or preventing a melanin concentrating hormone-mediated disorder in a subject, comprising administering to a subject in need of such treatment or prevention a compound of Formula I. ...

09/22/05 - 20050209196 - Dioxolane thymine and combinations for use against 3tc/azt resistant strains of hiv
The present invention relates to the use of a dioxolane thymine compound according to the chemical structure of Formula (I): where R1 is H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or phosphodiester group, for use in the treatment of HIV infections which exhibit ...

08/04/05 - 20050171061 - Aryloxyphenyl and arylsulfanylphenyl derivatives
wherein the substituents are as defined in the application. The compounds are valuable glycine transport inhibitors. ...



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