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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > O-glycoside > Polysaccharide PolysaccharidePolysaccharide patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.02/01/07 - 20070027107 - Compositions and methods for treating estrogen-dependent diseases and conditions A pharmaceutical composition for the treatment of an estrogen-dependent disease or condition comprises: (1) at least one polysaccharide selected from the group consisting of an alginate and a fucoidan in a quantity effective to treat an estrogen-dependent disease or condition; and (2) a pharmaceutically acceptable carrier. The composition can include ... 02/01/07 - 20070027106 - Charged sophorolipids and sophorolipid containing compounds optionally followed by acidolytic (treating with an acid) or hydrogenolytic deprotection (treating with a hydrogenolysis catalyst) which removes one of the groups R1 or R2 and replaces it with hydrogen. Also a sophorolipid containing composition containing a carrier and at least one sophorolipid described above. ... 01/25/07 - 20070021377 - Pharmaceutical composition comprising a macrolide immunomodulator Snyergistic combination of a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro-33-desoxyascomycin and a ceramide such as ceramide 3, LPC-9S or linoleic acid are provided, which are useful in particular in the treatment of dermatological or mucosal diseases such as atopic or contact dermatitis or dry skin, asteatotic eczema or ... 01/11/07 - 20070010484 - Method for treating or inhibiting the effects of injuries or diseases that result in neuronal degeneration and method for promoting neurogenesis Oligosaccharides, and in particular disaccharides, which are degradation products of chondroitin sulfate proteoglycan are effective for use in treating, inhibiting, or ameliorating the effects of injuries or diseases or disorders that result in or are caused by neuronal degeneration or of disorders resulting in mental and cognitive dysfunction. They are ... 01/11/07 - 20070010483 - Glucocerebroside treatment of liver disorders The present invention provides a method for the treatment of immune mediated or immune related diseases or disorders, infectious diseases, metabolic disorders and cancer in mammalian subjects. This method comprises the administration of a naturally occurring, mammalian intermediary metabolite or T cell receptor ligand, preferably a glucosylceramide, to a mammalian ... 01/11/07 - 20070010482 - Polysaccharide derivatives and uses in induction of an immune response The present invention generally provides compositions comprising a polysaccharide derivative, and methods of their preparation and use for the prevention or treatment of diseases caused by Neisseria meningitidis bacteria, particularly group B (NmB) strains, and by E. coli K1. The invention provides a de-N-acetylated PS derivative in which one or ... 01/11/07 - 20070010481 - Solid state irradiation of hyaluronan-based solid preparations, its derivatives and mixtures in an unsaturated gaseous atmosphere and their use The present invention relates to a range of new products, production of biocompatible solid compositions based on hyaluronan and its derivatives using ionizing radiation in the solid state in the presence of an unsaturated gas under specified reaction conditions and the uses thereof. ... 01/11/07 - 20070010480 - Dietary food items for a weight control or weight loss diet The invention relates to dietetic foods in the context of weight control or weight reduction, comprising at least one n3 fatty acid (omega-3) in combination with dietary fibers. Advantageously, the foods further comprise a balanced ratio of carbohydrates, protein and fat. Preferably, the inventive foods comprise a balanced ratio of ... 12/28/06 - 20060293278 - Novel therapeutic uses of glucan A process for the production of β-(1,3)(1,6) glucan from a glucan containing cellular source is described, together with compositions and uses/methods of treatment involving glucan. The process of the invention comprises the steps of: (a) extracting glucan containing cells with alkali and heat, in order to remove alkali soluble components; ... 12/28/06 - 20060293277 - Cross-linked gels of hyaluronic acid with hydrophobic polymers and processes for making for making them The present invention provides for compositions of hyaluronic acid cross-linked with at least one other hydrophobic polymer to form a copolymer gel. The preferred composition is a formulation containing hyaluronic acid or its derivatives and a silicone base polymer with a functional group capable of reacting with the preferred cross-linker. ... 12/28/06 - 20060293276 - Use of lipid conjugates in the treatment of disease This invention provides a method of preventing asthma, allergic rhinitis, or chronic obstructive pulmonary disease in a subject comprising the step of administering to a subject a compound comprising a lipid or phospholipid moiety bond to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or ... 12/21/06 - 20060287277 - Novel therapeutic uses of glucan A process for the production of β-(1,3)(1,6) glucan from a glucan containing cellular source is described, together with compositions and uses/methods of treatment involving glucan. The process of the invention comprises the steps of: (a) extracting glucan containing cells with alkali and heat, in order to remove alkali soluble components; ... 12/21/06 - 20060287276 - Compositions comprising oligosaccharides The present invention concerns compositions comprising a saccharide for the inhibition of pathogen adhesion to mammalian cells. ... 12/07/06 - 20060276431 - Methods for treating severe acute respiratory syndrome The invention provides methods for treating severe acute respiratory syndrome (SARS) with lipopolysaccharides. ... 12/07/06 - 20060276430 - Formulations for mediating inflammation and for reducing blood cholesterol The invention provides formulations for mediating inflammation and for lowering blood cholesterol. For example, inflammation of the intestine, retina or neural tissues, may be mediated. Further the formulations are effective in decreasing blood cholesterol absorption. The formulations comprise at least one ganglioside, which may be selected from the group consisting ... 11/30/06 - 20060270627 - Synthetic oligomannosides, preparation and uses thereof A pharmaceutical composition including a therapeutically effective amount of at least one oligomannoside produced by chemical synthesis which is homologous to a wall oligomannoside of an infectious organism or pathogen, or a derivative thereof, and a pharmaceutically acceptable vehicle. ... 11/30/06 - 20060270626 - Crude exopolysaccharides produced from phellinus baumii mycelium having hypoglycemic activity and preparation method thereof The present invention relates to a crude exopolysaccharides (EPS) produced from Phellinus baumii mycelium comprising mannose and/or arabinose and a preparation method thereof. ... 11/23/06 - 20060264399 - Compositions for breast implant filling and methods of use The methods and compositions disclosed herein describes a solution containing at least one block co-polymer that is a liquid at lower temperatures and transitions to a gel at higher temperatures. The compositions are useful, for example, as an alternative to saline or silicone-gel as fillers for prostheses. ... 11/09/06 - 20060252727 - Medicinal compositions and therapeutic methods for treating arthritis and other painful conditions The compositions of this invention comprise a mixture of (1) phenylanine and a dietary food supplement, (2) leucine and a dietary food supplement, and (3) hydrocinnamic acid and a dietary food supplement. The compositions are used for medicinal purposes, to alleviate acute and chronic arthritis and other painful conditions. ... 11/09/06 - 20060252726 - Composition and method for treating nosebleeds A composition and method for treating nosebleed, that is, epistaxis. The composition comprises bismuth subgallate and a vasoconstriction agent, preferably oxymetazoline. The composition is preferably a paste administered intranasally. ... 11/09/06 - 20060252725 - Use of prebiotics for preventing or treating oxidation stress The invention relates to the use of prebiotics for the preparation of food preparations, functional foods, or pharmaceutical compositions for preventing or treating oxidative stress in particular linked to the consumption of fructose. The invention also relates to a food preparation comprising simple carbohydrates, in particular fructose, in combination with ... 11/02/06 - 20060247206 - Minimally invasive clinical treatment method for closure of umbilical hernias The present invention is a minimally invasive clinical method for closing hernias and other abnormal openings existing within the body; and is a unique alternative to conventional surgery and routine surgical techniques for correcting such medical defects. The clinical applications for the present methodology can be used for the in-vivo ... 11/02/06 - 20060247205 - Very high molecular weight beta-glucans The invention pertains to compositions and therapeutic and prophylatic methods for treating/preventing infections in an animal or human by administering a soluble β-glucan composition comprising β-glucan molecules having an average molecular weight of at least 1,000,000 daltons, as determined by multi-angle laser light scattering (VHMW-glucan). ... 11/02/06 - 20060247204 - New therapeutic use of chondroitin sulphate The present invention relates to the use of an alkaline or alkaline earth metal chondroitin sulphate, which comes from an enzymatic hydrolysis of animal cartilage, for the preparation of a medicament for the treatment or prevention of psoriasis with skin affection in a mammal. Preferably the sodium chondroitin sulphate has ... 10/26/06 - 20060241079 - Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption The invention provides methods of using beta glucans to treat conditions associated with bone loss or low bone density as well as methods for promoting bone growth in situations where enhanced bone growth is desirable. In the invention methods beta glucans are administered so as to enhance the development of ... 10/19/06 - 20060234978 - Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis The invention provides compositions and methods useful for the treatment and/or prevention of interstitial cystitis and/or a related urinary tract condition in man or in animals. Specifically, provided are compositions specially formulated for direct instillation into the bladder and/or parenteral use in the treatment and/or prevention of interstitial cystitis. Compositions ... 10/19/06 - 20060234977 - Antiviral compostion comprising a sulphated glucose polymer and a bacteriostatic agent There is described a pharmaceutical composition comprising a glucose polymer or a mixture of glucose polymers and optionally, salts thereof and a non-sensitising bacteriostatic agent, such as sorbic acid. There is also described a method of treatment, alleviation or prevention of HIV-1 or a related virus or other sexually transmitted ... 10/12/06 - 20060229276 - Use of glycosoaminoglycans for the prevention and treatment of sepsis The present invention discloses an unexpected use of glycosoaminoglycans such as low molecular weight heparin in the prevention and treatment of sepsis. Low molecular weight heparin is capable of preventing mortality and prolonging survival in a mouse model of S. aureus-induced septic death. Two other glycosaminoglycans, namely chondroitin sulfate A ... 10/05/06 - 20060223781 - Process for induction of intramolecular migration of sulfates, phosphates, and other oxyanions This present invention provides methods for structural modification of a molecule containing a hydroxyl group and an oxyanion amide or oxyanion ester group on adjacent or nearby atomic positions. The oxyanion, such as sulfate and phosphate, can be transferred to the hydroxyl group when the molecule is treated with a ... 09/21/06 - 20060211653 - Pharmaceutical compositions comprising aloe pectins, and methods for their production and use Pectins having a combination of unexpectedly high molecular weights and low degrees of methylation have been isolated from Aloe vera plants, are superior gel pectins for forming calcium cross-lined gels. Such pectins can be obtained by extracting homogenized Aloe Vera plants or portions thereof. These pectins can be used to ... 09/21/06 - 20060211652 - Method of making a partially hydrolyzed fucoidan composition Methods of making partially hydrolyzed fucoidan. Fucoidan from brown seaweeds is partially hydrolyzed and then mixed with other ingredients for use as a dietary supplement in beverage, capsule, or tablet form. The fucoidan is partially hydrolyzed with acid and heat. The partially hydrolyzed fucoidan can also be sulfonated. Other ingredients ... 09/21/06 - 20060211651 - Persulfated oligosaccharide acting on selectins and chemokine A persulfated saccharide compound capable of acting on selectin and chemokine. According to the present invention, there are provided a saccharide compound capable of interacting with L-selectin, P-selectin and chemokine; a pharmaceutical composition; and an agent for treating or preventing a disease of which sideration is associated with biological events ... 09/14/06 - 20060205690 - Glycosaminoglycans for treatment of emotional dysfunctions The present invention relates to the use of glycosaminoglycan fractions having an average molecular weight of 2400 (∀200) D for the preparation of pharmaceutical compositions suitable for the treatment of emotional dysfunctions, especially depressive disorders, anxiety disorders, anxiety neurosis, agitation, confusion. ... 08/31/06 - 20060194760 - Cosmetic preparations The invention relates to cosmetic preparations containing (a) water-soluble β-(1,3) glucans, substantially devoid of β-(1,6) links, and (b) chitosans. The agents are suitable for hair care and personal hygiene and can also be used for sun protection. ... 08/31/06 - 20060194759 - Topical compositions and methods for treating pain and inflammation A topical composition and method for treating pain and inflammation by administering an effective amount of a topical composition comprising an anti-inflammatory steroid such as hydrocortisone, a topical anesthetic such as lidocaine, menthol, and a medically acceptable carrier into which the forgoing are incorporated. A chondroprotective agent can also be ... 08/31/06 - 20060194758 - Cross-linking of low and high molecular weight polysaccharides preparation of injectable monophase hydrogels and polysaccharides and dydrogels thus obtained A process for the crosslinking of at least one polymer selected from polysaccharides and derivatives thereof, which is carried out in an aqueous solvent by the action of an effective and non-excessive amount of at least one crosslinking agent, characterized in that it is carried out on a mixture containing ... 08/31/06 - 20060194757 - Cystitis treatment with high dose chondroitin sulfate Interstitial cystitis and related GAG-deficient conditions of the bladder and urinary tract are treated by instillation of high dose chondroitin sulfate, such as 400 mg/20 mL. The higher dose of chondroitin is effective for the rapid reduction of symptoms, particularly in patients with severe and otherwise recalcitrant cystitis. ... 08/24/06 - 20060189572 - Composition for local anesthesia A composition for local anesthesia which comprises a local anesthetic as an active ingredient and an agent for maintaining anesthetic action selected from the group consisting of acidic mucopolysaccharides such as sodium chondroitin sulfate and cellulose derivatives such as hydroxypropylmethylcellulose, and does not contain catecholamines, which has durability of anesthetic ... 08/24/06 - 20060189571 - Use of lipid conjugates in the treatment of infection This invention provides compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating a pathogenic effect on a cell, including, inter alia, infection with intracellular pathogens. Also provided are compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating an infection in a subject. ... 08/24/06 - 20060189570 - Use of lipid conjugates in the treatment of infection This invention provides compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating a pathogenic effect on a cell, including, inter alia, infection with intracellular pathogens. Also provided are compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating an infection in a subject. ... 08/24/06 - 20060189569 - Use of lipid conjugates in the treatment of infection This invention provides compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating a pathogenic effect on a cell, including, inter alia, infection with intracellular pathogens. Also provided are compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating an infection in a subject. ... 08/24/06 - 20060189568 - Use of lipid conjugates in the treatment of infection This invention provides compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating a pathogenic effect on a cell, including, inter alia, infection with intracellular pathogens. Also provided are compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating an infection in a subject. ... 08/24/06 - 20060189567 - Compound having affinity with calcified tissue The present invention provides a compound excellent in accumulation on calcified tissues and ensuring rapid excretion into urine as well as rapid clearance from blood, useful as a diagnostic agent and a therapeutic agent, etc. The compound is a compound having affinity with a calcified tissue represented by the following ... 08/17/06 - 20060183710 - Chlamydia oligosaccharides Oligosaccharides specific for Chlamydia mediate attachment of the organism to host cells. ... 08/17/06 - 20060183709 - Preparation of low molecular weight hyaluronic acid as a food supplement A process for preparing hyaluronic acid primarily as a food supplement which is capable of absorption and assimilation by the human body includes desirable control of both the purity and molecular weight range of the resulting product. Chicken comb tissue is subjected to one of two disclosed processes for extracting, ... 08/10/06 - 20060178342 - Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease This application provides methods and compositions for the treatment of cancer. The application provides compositions comprising hyaluronic acid and a chemotherapeutic agent such as irinotecan that are useful in the treatment of cancer. ... 08/10/06 - 20060178341 - Composition comprising soluble glucan oligomer from saccharomyces cerevisiae is2 inhibiting the swine influenza (siv) and transmissible gastroenteritis coronavirus (tgev) The present invention relates to the soluble glucan oligomer having a M.W. ranging from 1,000 to 10,000 prepared by treating insoluble beta-glucan isolated the cell wall of yeast variant IS2 with commercially available beta-glucan hydrolyzing enzymes. The soluble glucan oligomer showed potent efficacy on inhibiting activity of influenza virus and ... 08/10/06 - 20060178340 - Composition comprising soluble glucan oligomer from saccharomyces cerevisiae is2 for immune activation or prevention and treatment of cancer and the preparation method thereof The present invention relates to the soluble glucan oligomer having a M.W. ranging from 1,000 to 10,000 prepared by treating insoluble beta-glucan isolated the cell wall of yeast variant IS2 with commercially available beta-glucan hydrolyzing enzymes. The soluble glucan oligomer showed potent efficacy on promoting immune activity and on inhibiting ... 08/10/06 - 20060178339 - Crosslinkable polysaccharide derivative, process for producing the same, crosslinkable polysaccharide composition, and medical treatment material A crosslinkable polysaccharide derivative which has in the side chain of polysaccharide at least one active ester group reactive with an active hydrogen-containing group and which forms a crosslinked product through covalent bond between the active ester group and the active hydrogen-containing group upon contact with alkaline water. A composition ... 08/03/06 - 20060172968 - Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect where the U, R and R1 groups have the meanings indicated in the description. These glycosaminoglycan derivatives have antiangiogenic and heparanase-inhibiting activity and are devoid of anticoagulant activity. ... 08/03/06 - 20060172967 - Method for producing alkyl-esterified glycosaminoglycan A method for producing an alkyl-esterified glycosaminoglycan, which comprises the step of allowing a trialkylsilyldiazoalkane to act on a glycosaminoglycan to perform alkyl-esterification of carboxyl groups of the glycosaminoglycan, and an alkyl-esterified glycosaminoglycan having a property that it is not substantially degraded by a glycosaminoglycan degrading enzyme such as hyaluronidase ... 07/27/06 - 20060166930 - Medicinal composition for ophthal use containing acetylated hyaluronic acid The present invention provides an ophthalmic pharmaceutical composition containing acetylated hyaluronic acid and a pharmacologically acceptable carrier. Preferably, the average molecular weight of the acetylated hyaluronic acid is 10,000 to 1,000,000, and the acetyl group substitution number is from 2.0 to 4.0. In a preferred embodiment, this ophthalmic pharmaceutical composition ... 07/27/06 - 20060166929 - Sugar-chain asparagine derivatives and processes for the preparation thereof an asparagine-linked oligosaccharide derivative containing at least one fucose in N-acetylglucosamine on the nonreducing terminal side of an asparagine-linked oligosaccharide wherein the amino group of asparagine is modified with a biotin group or FITC group, a microplate having immobilized thereto a biotinated asparagine-linked oligosaccharide, and an affinity column having immobilized ... 07/27/06 - 20060166928 - Hyaluronic acid derivative gel and method for preparing the same The present invention relates to a hyaluronic acid derivative gel, obtained by amidation of a hyaluronic acid, or its cationic salt, and an amine group-containing saccharide compound, having excellent viscoelastic properties, and a method for preparing it. Especially, the hyaluronic acid derivative gel according to the present invention shows responses ... 07/27/06 - 20060166927 - Compounds that bind to the interferon-gamma, preparation method thereof and medicaments containing same in which X is a divalent spacer group that is sufficiently long to allow the two oligosaccharide fragments A and B to each bind to one of the peptide sequences 125 to 143 of the C-terminal ends of a γ-interferon (γ-IFN) homodimer, n represents an integer from 0 to 10, ... 07/20/06 - 20060160766 - Therapy-enhancing glucan A therapeutic composition for treatment of cancer in a mammal is disclosed. The composition comprises an effective amount of a glucan composition which is suitable for oral administration and for absorption through the gastrointestinal tract of the mammal, and at least one antibody for the cancer. A method of treating ... 07/13/06 - 20060154895 - Method of treating acquired immunedeficiency syndrome HIV infections are treated with sequential treatment regimens comprising a first regimen which is a combination of highly active antiretroviral therapy drugs selected from the group consisting of nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors to reduce the HIV levels; and a second treatment regimen which ... 07/13/06 - 20060154894 - Biologically active surfaces and methods of their use The invention relates to the immobilization of polysaccharides on a substrate. In particular, the invention relates to biologically active surfaces formed by the immobilization of glycosaminoglycans on a substrate. The invention also provides biologically active surfaces that contain one or more different glycosaminoglycans and, optionally, one or more other agents. ... 07/13/06 - 20060154893 - Exopolysaccharides delivery system for active molecules The present invention relates to a delivery system for delivery of an active molecule to a patient, the delivery system comprising a population of exopolysaccharide micelles, each micelle defining a core for containing the active molecule. ... 07/06/06 - 20060148755 - Regimens for intra-articular viscosupplementation The invention provides viscosupplementation methods for treating osteoarthritis and joint injury with HA-based viscosupplements, particularly viscosupplements with an intra-articular residence half-life shorter than 3 weeks. Viscosupplements for use in the methods of the invention may be further characterized in that they contain less than 20 mg/ml HA, at least 5% ... 07/06/06 - 20060148754 - Composition for treating and/or preventing dysfunctions associated with type 2 diabetes mellitus and insulin resistance The present invention relates to the use of a composition for treating, preventing and/or improving metabolic dysfunctions associated with type 2 diabetes mellitus and insulin resistance, said composition comprising acetogenic fibers ... 06/22/06 - 20060135471 - Anti-obesity compositions The present invention relates to compositions and methods for treating obesity. More particularly, the invention relates to a composition comprising a lipase inhibitor such as orlistat, and glucomannan such as konjac as well as methods for utilizing such compositions and kits for carrying out this method. ... 06/22/06 - 20060135470 - Composition and method for treatment and prevention of traumatic synovitis and damage to articular cartilage The invention provides compositions useful for the treatment and/or prevention of damage to diarthrodial (synovial) joints and, in particular, traumatic synovitis, inflammation of the synovial membrane, and damage to the articular cartilage of the joint. Specifically, provided are compositions specially formulated for intra-articular and/or parenteral use in the treatment and/or ... 06/22/06 - 20060135469 - Separate type medical material A separate type medical material containing a hyaluronic acid ester derivative, which satisfies the storage stability of a hyaluronic acid ester derivative and avoidance of irritation and pain at the time of injecting a therapeutic agent for joints, is provided. A separate type medical material comprising liquid (A) which is ... 06/15/06 - 20060128656 - Charged phospholipid compositions and methods for their use The invention provides a pharmaceutical composition comprising a synthetic or naturally occurring charged phospholipid, which is formulated into a dosage form for administration to a subject or which is administered as a food additive. Negatively charged phospholipid composition increase the net negative charge on intravascular lipoproteins, enhance the clearance of ... 06/15/06 - 20060128655 - Use of hyaluronic acid or its derivatives to enhance delivery of antineoplastic agents A combination for administration to a mammal which combination employs a therapeutically effective amount of a medicinal and/or therapeutic agent to treat a disease or condition and an amount of hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments and subunits of hyaluronic acid sufficient to facilitate ... 06/08/06 - 20060122151 - Composition containing an association of aspirin and an anti-xa oligosaccharide and use of an anti-xa oligosaccharide optionally in combination with aspirin The invention relates to the use of a synthetic oligosaccharide which is a selective inhibitor of factor Xa acting via antithrombin III, alone or in association with aspirin, for the preparation of medicaments intended for preventing or treating thromboembolic diseases occurring in a mammal which has undergone a percutaneous transluminal ... 06/08/06 - 20060122150 - Pharmaceutical composition and method for treating a joint-capsule arthropathy A pharmaceutical composition for use in treating a joint-capsule arthropathy comprising an effective amount of one or more of a locally administered, optionally encapsulated therapeutic agent in admixture with a hyaluronic acid delivery vehicle and a method for use thereof in treating a joint-capsule arthropathy by intra-articular injection. ... 06/08/06 - 20060122149 - Extraction and purification method for cereal beta-glucan A novel method to extract and purify cereal β-glucan is described. Cereal β glucans are distinctive polymers of glucose differentiated from other polymers not only by their source but also by their physicochemical properties. The high purity of the cereal β-glucan obtained according to the present invention allows for the ... 06/08/06 - 20060122148 - High affinity receptors for helicobacter pylori and use thereof The present invention describes an oligosaccharide substance or receptor binding to Helicobacter pylori, and the use thereof in, e.g., pharmaceutical and nutritional compositions for the treatment of conditions due to the presence of Helicobacter pylori. The invention is also directed to the use of the receptor for diagnostics of Helicobacter ... 06/08/06 - 20060122147 - Combination preparation of hyaluronic acid and at least oe local anesthetic and the use thereof The invention relates to a combination preparation comprising an active agent A from the group hyaluronic acid, the salts and fragments thereof, at least one active agent B from the group of local anaesthetics and derivatives thereof and also if necessary further additives. These combination preparations are used for the ... 06/01/06 - 20060116349 - Methods and compositions for administration of iron for the treatment of restless leg syndrome The invention is directed to methods of treating Restless Leg Syndrome by administering iron complexes with specificed iron release rates or specified iron core size. ... 06/01/06 - 20060116348 - Polymer grafting by polysaccharide synthases The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate synthase from Pasteurella multocida. The present invention also relates to coatings for biomaterials wherein the coatings provide protective properties to the biomaterial and/or act as a bioadhesive. Such coatings ... 06/01/06 - 20060116347 - Methods and compositions to treat glycosaminoglycan-associated molecular interactions Therapeutic compounds and methods for inhibiting a glycosaminoglycan (GAG)-associated molecular interaction in a subject, whatever its clinical setting, are described. ... 06/01/06 - 20060116346 - Taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives The present invention relates to water-soluble taxanes covalently bounded tohyaluronic acid or hyaluronic acid derivatives, and in particular to paclitaxel and docetaxel, useful for the preparation of pharmaceutical compositions to be used in the field of oncology, in the treatment of autoimmune disorders and of restenosis. The invention also relates ... 05/18/06 - 20060105991 - Medical composition for protuberance of epithelium A medical composition for protuberance of epithelium, which comprises a solution comprising a polysaccharide or a medically acceptable salt thereof, wherein the solution has a viscosity of: (1) from 50 to 500 mPa·s at a shear rate of from 7.7 to 10.0 s−1; (2) from 45 to 300 mPa·s at ... 05/18/06 - 20060105990 - Antiadhesive carbohydrates Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells. Said preparation contains at least one carbohydrate having an uronic acid unit on one of the ends thereof. 10 to 100% of the ... 05/18/06 - 20060105989 - Food for improving arthritis The present invention provides a food for improving arthritis comprising proanthocyanidins (A) and a mucopolysaccharide and/or an amino sugar (B). Preferably, the proanthocyanidins contain at least 20 wt % of OPCs. ... 05/18/06 - 20060105988 - Antipruritic composition for external use on skin It is the object of the present invention to provide a composition which has an antipruritic effect on skin and further exhibits good appearance and feeling of usage. The present invention relates to an antipruritic composition for external use on skin, which contains a mucopolysaccharide or a derivative thereof in ... 05/18/06 - 20060105987 - Sulfur-containing phospholipid derivatives The present invention provides a lipid compound comprising at least one non-polar moiety and a polar moiety, wherein each or at least one non-polar moiety is of the formula X—Y-Z-, wherein X is a hydrocarbyl chain, Y is selected from at least one of S, Se, SO2, SO, and O, ... 05/11/06 - 20060100174 - Configuration of glycosaminoglycans The present invention provides stable glycosaminoglycan (GSG) structures and methods of use of such GAG structures. These structures comprise a core of free GAG, a coating of crosslinked GAG surrounding the core, and a layer of a positively charged moiety surrounding the crosslinked GAG layer. These GAG structures provide improved ... 05/11/06 - 20060100173 - Ophthalmic solution An improved ophthalmic composition comprising an anionic polymeric substance, such as Hyaluronic Acid and/or Carboxymethylcellulose, in combination with any of various cationic monomeric or dimeric antimicrobial agents, such as Cetylpyridinium Chloride and/or Alexidine Dihydrochloride, wherein said compositions provide additional comfort and biocompatibility with lenses without significantly affecting the antimicrobial efficacy ... 05/11/06 - 20060100172 - Use of prebiotics, preferably glucooligosaccharide, for the prevention of the onset of type ii diabetes The invention relates to the use of prebiotics for the preparation of food or pharmaceutical compositions which are intended for the treatment and/or prevention of hyperglycaemic syndromes and, in particular, for the treatment of Type II diabetes and/or the prevention of the onset of Type II diabetes in patients with ... 05/11/06 - 20060100171 - Branched alpha-glucans for weight management Highly branched α-glucan having an average molar weight of at least 105 Da can be used for inducing or enhancing satiety and/or satiation in humans or animals by incorporation of the α-glucan into a liquid nutritional or pharmaceutical composition, preferably together with a food protein. The α-glucan induces a viscosity ... 05/04/06 - 20060094689 - Production of fungal extracellular immune stimulating compounds A process is described for the production of an immunostimulant by submerged cultivation of Lentinus edodes in which mycelium from agar plates or a fermentation broth is added to a liquid medium in a shake flask or a bioreactor containing nutrients such as malt extract, yeast extract, peptone and glucose ... 05/04/06 - 20060094688 - Histamine release inhibitor The present invention provides a histamine release inhibitor comprising a pectin or a salt thereof or a pectin hydrolysate as an active ingredient, and a pharmaceutical composition, a cosmetic, and food and drink comprising the inhibitor. ... 04/27/06 - 20060089330 - Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated method for the synthesis of GPIs and fragments thereof. ... 04/20/06 - 20060084631 - Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof Methods and compositions for treating or preventing microbial infection in mammals with sulfated polysaccharides wherein the polysaccharides have a degree of sulfation effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by ... 04/20/06 - 20060084630 - Method for synthesis of beta glucans The invention provides a method for forming P-glucoside linkages in carbohydrate polymers, particularly synthetic glucan molecules, by attaching a protecting group to the C2 position of a glucoside donor. The protecting group of the invention stabilizes the dioxolenium ion and prevents orthoester formation to promote the β linkage and inhibit ... 04/20/06 - 20060084629 - Immune system activating formula composed of selected long chain polysaccharides from natural sources A combination of two, specialized, high molecular weight-long chain fractions isolated from Aloe Vera and Maitake TD to stimulate immune system activity comprise long chain-high molecular weight polysaccharides which activate the body's natural immune response, triggering an increase in the production of macrophages, T-cells, B-cells, natural killer cells, cytokines and ... 04/13/06 - 20060079482 - Ophthalmic compositions including lubricant, deturgescent agent, and glycosaminoglycan and methods of using the same Ophthalmic compositions are provided that include a lubricant, a deturgescent agent, a glycosaminoglycan, and water. Methods of using the ophthalmic compositions are also provided. ... 04/13/06 - 20060079481 - Method of treating/preventing mucositis A method of treating and/or preventing mucositis which is an inflammation and ulceration of the mucous membranes, typically resulting from a toxic reaction to chemotherapy and/or radiotherapy by the application of water soluble immunomodulatory β-glucan. ... 04/06/06 - 20060074052 - Compositions and methods for treating mammals with modified alginates and modified pectins A modified alginate and/or modified pectin composition and method for preventing and/or treating diseases and/or conditions caused by circulating agents such as poisonous heavy metals, environmental toxins, calcium and cholesterol, is provided. The composition includes a modified alginate having a molecular weight of no more than 40,000 daltons and/or a ... 04/06/06 - 20060074051 - Therapeutic stem cell growth factor composition, anti-inflammatory composition, and uses thereof The present invention relates to a composition and uses thereof for treatment of damaged tissue comprising at least one essential amino acid in L form and at least one essential lipid; wherein the composition is administered to a mammal suffering from severe tissue damage. The invention further relates to a ... 04/06/06 - 20060074050 - Composition and method for treating hyperproliferative diseases The present invention is directed to methods and compositions for treatment of hyperproliferative diseases. The composition of the invention comprises a carbohydrate having a backbone comprising polygalacturonan and a ligand of peripheral benzodiazepine receptor. The present compositions and methods are used to treat various cancers and other diseases where cells ... 04/06/06 - 20060074049 - Use of heparinoids for treatment and prevention of dementia Methods for treating, preventing, or reducing development of non-traumatic interneuron pathologies are described herein. Also described are methods for treating or preventing dementia (e.g., dementia associated with HIV, AIDS, or Alzheimer's disease). ... 04/06/06 - 20060074048 - Mixed esters of hyaluronic acid with retinoic and butyric acids The present invention relates to mixed esters of hyaluronic acid, wherein the hydroxyl groups are partially esterified with retinoic and butyric acids. These mixed esters are characterized by specific degrees of esterification and by a high ratio between the degree of substitution with butyric acid and retinoic acid. They exhibit ... 03/30/06 - 20060069064 - Methods for facilitating recovery of functions of endogenous or implanted or transplanted stem cells using hyaluronic acid Hyaluronic Acid (HA) is an essential component of tissue extracellular matrices that contributes to the architecture of stem cell niches, which determine the fate of stem cells. Decreased levels of HA are found in subjects experiencing a variety of pathological conditions, as well as in subjects receiving a variety of ... 03/30/06 - 20060069063 - Crosslinked polygalacturonic acid used for postsurgical tissue adhesion prevention Disclosed is a crosslinked PGA that is obtained by crosslinking PGA polymer with a crosslinking reagent to develop a three-dimensional crosslinked PGA structure. The crosslinked PGA has good tissue antiadhesion and biocompatibility. ... 03/09/06 - 20060052339 - N-acyl modified polysaccharides and pharmaceutical compositions comprising same and dietary calcium This invention relates to novel N-acyl modified polysaccharides and pharmaceutical compositions comprising the modified polysaccharides and comprising dietary calcium as a mixture or as a salt. Further the invention relates to processes for using such compounds to inhibit lipases, to lower cholesterol, to lower the absorption of dietary fat, or ... 03/09/06 - 20060052338 - N-acyl and quaternary ammonium modified polysaccharide fibers This invention relates to novel N-Acyl and N-Alkyl modified quaternary ammonium polysaccharide fibers, or both N-Acyl and N-Alkyl modified quaternary ammonium polysaccharide fibers and pharmaceutical compositions comprising the modified fibers. Further the invention relates to processes for using such modified polysaccharide fibers to lower cholesterol, to lower a mammal's absorption ... 03/09/06 - 20060052337 - Polysaccharide and composition from antrodia camphorata and use thereof The invention relates to polysaccharide extracted from Antrodia camphorata and the method for preparing the polysaccharide. The invention also relates to compositions and methods for hepatoprotective effect. ... 03/09/06 - 20060052336 - Process for preparing a sterile high molecular weight hyaluronic acid formulation A process for preparing a sterile ready-to-use aqueous pharmaceutical formulation comprises a high molecular weight hyaluronic acid salt (HA) at a specified concentration, comprising the steps of: providing an aqueous formulation comprising high molecular weight HAat a concentration of less than the specified final concentration; passing said aqueous formulation through ... 03/09/06 - 20060052335 - Chondroitin synthetase and dna encoding the enzyme A human-derived novel chondroitin synthase, which is an enzyme for synthesizing a fundamental backbone of chondroitin and has both glucuronic acid transferase activity and N-acetylgalactosamine transferase activity. ... 03/02/06 - 20060046974 - N-acyl modified polysaccharides and pharmaceutical compositions comprising same This invention relates to novel N-acyl modified polysaccharides and pharmaceutical compositions comprising the modified polysaccharides. Further the invention relates to processes for using such compounds to inhibit lipases, to lower cholesterol, to lower the absorption of dietary fat, or as a dietary fiber supplement. In a preferred aspect of the ... 02/23/06 - 20060040895 - Aesthetic use of hyaluronan A method to rejuvenate tissue by injection of a solution containing between about 0.5% and about 10% hyaluronic acid is described. The application of the solution to tissue regions having wrinkles, line, creases, abnormalities and the like is effective in diminishing the signs of aging. ... 02/23/06 - 20060040894 - Compositions and methods using hyaluronic acid Compositions and devices including hyaluronic acid and a compound that inhibits degradation of hyaluronic acid, and methods of making and using same. ... 02/23/06 - 20060040893 - Immunomodulatory methods using oligosaccharides Methods for modulating immune responses are provided. The methods involve contacting an immune cell with an agent that modulates interaction of a compound comprising a Lewis antigen with the immune cell such that production by the immune cell of at least one cytokine that regulates development of a T helper ... 02/23/06 - 20060040892 - Process for synthesizing oil and surfactant-free hyaluronic acid nanoparticles and microparticles A method for synthesizing uniformly sized hyaluronic acid (“HA”) particles that are substantially free from oil and surfactant contaminants. The method comprises crosslinking HA chains with 1-ethyl-3-(3-dimethlyaminopropyl) carbodiimide hydrochloride (“EDAC”) and adipic acid dihydrazide in a water/acetone mixture. ... 02/23/06 - 20060040891 - Lipid a and other carbohydrate ligand analogs The core structure of pentaerythritol has been used as a replacement for one or both sugars in lipid A, leading to the generation of a series of lipid A analogs. These lipid A analogs may further differ from lipid A with respect to, e.g., the number, nature and location of ... 02/02/06 - 20060025379 - Small molecule stimulators of neuronal growth Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical conditions associated with neurological disorders using the compounds and compositions provided herein. ... 02/02/06 - 20060025378 - Dose dependent elimination of ha and cell receptor stimulation The invention provides a method to alter elimination kinetics of hyaluronic acid (HA) in a patient is disclosed. Administration of HA to a patient, followed by at least one subsequent administration results in an alteration of the ability of the patient to eliminate HA. Also disclosed is a method for ... 02/02/06 - 20060025377 - Inhibitor of angiogenesis and kit for treating cancer comprising the inhibitor The inhibitor of angiogenesis is characterized by containing tetraacetylphytosphingosine and the kit for inhibiting angiogenesis is characterized by the inhibitor. The inhibitor and kit are effective in treating and preventing disorders in connection with extremely increased angiogenesis such as angioma, tumor and psoriasis by effectively inhibiting angiogenesis. Furthermore, they are ... 01/19/06 - 20060014719 - Method for treating neurodegenerative diseases The present invention is directed to methods and compositions for treatment of neurodegenerative diseases. In particular embodiments, the invention is directed to the treatment of Alzheimer's disease, MS, ALS, Huntington's Disease. In other embodiments, the invention is directed to the treatment of multiple sclerosis. ... 01/19/06 - 20060014718 - Epimerized derivatives of k5 polysaccharide with a very high degree of sulfation A new method is described for the oversulfation of epiK-N sulfate to obtain an epiK5-amine-O-oversulfate with very high sulfation degree which, by subsequent N-sulfation, provides new epiK5-N,O-oversulfate-derivatives with a sulfation degree of at least 4, basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical ... 01/19/06 - 20060014717 - Therapeutic compositions for use in prophylaxis or treatment of diarrheas The invention provides a therapeutical composition comprising purified fractions of compounds being or containing a pathogen-inhibiting oligosaccharide sequence for use as a medicament. The present invention especially describes an oligosaccharide-containing substance or receptor binding to diarrheagenic Escherichia coli and/or zoonotic Helicobacter species, and use thereof in, e.g., pharmaceutical, nutritional and ... 01/12/06 - 20060009419 - Therapy-enhancing glucan The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. The glucan does not stimulate the induction of ... 01/05/06 - 20060003964 - Dilution resistant viscoelastic compositions A method of performing viscosurgery and intra-articular therapy and a dilution resistant viscoelastic composition are disclosed. One embodiment of the dilution resistant composition comprises a hyaluronate-based viscoelastic agent and a low viscosity, polymer-containing solution. The hyaluronate-based viscoelastic can be an aqueous solution sodium hyaluronate having an average molecular weight greater ... 12/29/05 - 20050288250 - Novel use of carbohydrates and compositions A process for preventing colon fermentation imbalance by the administration of a composition of a slowly fermented carbohydrate complex oligomer or polymer. A method of preparing the composition by nutritionally, nutraceutically and/or pharmacologically formulating the carbohydrate oligomer or polymer is an aspect of this process. ... 12/22/05 - 20050282774 - Method and pharmaceutical to treat spinal discs An injectable for injection into a spinal disc, and a method to treat a spinal disc with the injectable. The injectable consists essentially of chondroitin sulfate and glucosamine HCl buffered to a pH above about 6.0. ... 12/22/05 - 20050282773 - Modified polysaccharides in combination with anti-cancer drugs for enhanced treatment of cancer Modified polysaccharide compositions and their use in combination with at least one anti-cancer drug for treating subjects with cancer, reduce toxicity and inhibit metastasis, are described. The modified polysaccharide includes a saccharide backbone being less than 5% esterified and containing repeating units, wherein each repeating unit has a plurality of ... 12/22/05 - 20050282772 - New dietary supplement composition for obesity and inflammation The present invention relates to dietary supplement phytochemical compositions, comprising calcium, potassium double salt of (−)-hydroxycitric acid and glucosamine hydrochloride, and optionally boswellic acids, curcuminoids, 5-hydroxytryptophan, chondroitin sulfate and L-carnitine. The claimed compositions are useful in dietary supplements, nutritional supplements or pharmaceutical preparations for weight loss and inflammatory epidemics. ... 12/22/05 - 20050282771 - Methods for treating bleeding disorders using sulfated polysaccharides Methods for treating bleeding disorders using non-anticoagulant sulfated polysaccharides (NASPs) as procoagulants are disclosed. NASPs can be administered as single agents, or in combination with one another, or with other medications (such as factors VII, VIII and IX) to promote hemostasis. In particular, the use of NASPs in treatment of ... 12/22/05 - 20050282770 - Synthetic glycosulfopeptides and methods of synthesis thereof A new class of synthetic glycosulfopeptides (GSPs) which have one or more sulfated tyrosine residues and a glycan linked to the peptide, the glycan preferably including a sialyl Lewisx group or a sialyl Lewisa group. In a preferred version the GSPs have an O-glycan comprising a β1,6 linkage to a ... 12/15/05 - 20050277618 - Methods The invention provides a method of identifying a compound useful for treatment of IBD which comprises assaying the compound for its ability to modulate the activity or amount of 3OST4. The assay is selected from measurement of 3OST4 activity using a cell line which expresses 3OST4 or using purified 3OST4 ... 12/08/05 - 20050272696 - Methods of selectively treating diseases with specific glycosaminoglycan polymers The present invention demonstrates that defined, specific GAG molecules have discerned differential effects, and that different types of cancers are prevented from proliferating and/or killed by oligosaccharides of different sizes; one size sugar does not treat all cancers effectively. Likewise, certain size GAGs have more potent angiogenic properties; thus, mixtures ... 12/08/05 - 20050272695 - Fast dissolving dried hyaluronic acid product The present invention relates to atomized products comprising hyaluronic acid or a salt thereof, which product has a high solubility in an aqueous solvent, various compositions and articles comprising the product or compositions of the invention, methods of producing the product of the invention, and uses thereof. ... 12/08/05 - 20050272694 - Composition containing beta-glucan and constipation-relieving drug, immunopotentiatior, and skin moistening agent using the composition The present invention provides a composition containing β-glucan in which the physiologically active effects of β-1,3-1,6-glucan contained in a cultured composition of a bacterium belonging to the genus Aureobasidium sp. are further enhanced, and a constipation-relieving drug, preparation an immunopotentiator, and a skin moistening agent using the composition. A composition ... 12/01/05 - 20050267069 - Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease This application provides methods and compositions for the treatment of cancer. The application provides compositions comprising hyaluronic acid and a chemotherapeutic agent such as irinotecan that are useful in the treatment of cancer. ... 12/01/05 - 20050267068 - Dried and agglomerated hyaluronic acid product The present invention relates to products comprising hyaluronic acid or a salt thereof, which product is dried and agglomerated as defined herein, various compositions and articles comprising the product or compositions of the invention, methods of producing the product of the invention, and uses thereof. ... 11/24/05 - 20050261241 - Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses Dermatan sulfates and/or O-desulfated heparins useful in treating and preventing heparinoid-induced autoimmune responses, in particular heparin-induced thrombocytopenia (HIT) and its associated disease states. The dermatan sulfates comprise repeating disulfated and/or trisulfated disaccharide units of L-iduronic acid and N-acetyl-D-galactosamine. The O-desulfated heparins comprise heparin molecules selectively O-desulfated at the 2-O and/or ... 11/24/05 - 20050261240 - Carrageenan based antimicrobial compositions Disclosed are compositions for inhibiting transmission of a sexually transmitted infection that contain one or more carrageenans, including lambda carrageenan. Also disclosed are methods for making and using the compositions. ... 11/17/05 - 20050256080 - Method for reducing malodor of chondroitin The present invention relates to a method of removing or masking odor associated with chondroitin derived from marine life. The method comprises blending the chondroitin with citric acid, silicon dioxide, and optionally a flavorant to yield a substantially non-malodorous blend. ... 11/17/05 - 20050256079 - Process for the manufacture of n-acyl-(epi)k5-amine-o-sulfate-derivatives and products thus obtained A new method is described for the oversulfation of (epi)KS-N sulfates to obtain (epi)K5-amine-O-oversulfates at extremely high degree of sulfation and for the transformation of these intermediates into new Nacyl-(epi)K5-amine-O-oversulfates basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical field. Also described are pharmaceutical ... 11/10/05 - 20050250735 - Modified pectins, compositions and methods related thereto The present invention provides compositions of modified pectin and for preparing and using them. ... 11/10/05 - 20050250734 - Compositions, kits, and methods for the treatment of conditions associated with elevated cholesterol levels Disclosed herein are methods of treating a condition associated with elevated cholesterol levels are provided, comprising administering to a mammal in need of such treatment a safe and effective amount of a cholesterol biosynthesis inhibitor and a soluble fiber. Further disclosed herein are kits comprising a first composition comprising a ... 11/03/05 - 20050245481 - Method of producing teicoplanin Disclosed is a method of producing teicoplanin. The method includes purifying teicoplanin from a culture broth, obtained by culturing microorganisms capable of producing teicoplanin by a porous adsorption resin under selective elution conditions and recovering highly pure teicoplanin using activated carbon and/or ultrafiltration. In this regard, the method can further ... 11/03/05 - 20050245480 - Methods of using beta glucan as a radioprotective agent The invention relates to methods for treating and preventing radiation and/or chemotherapy related injury and/or afflictions, such as myelosuppression and decreased macrophage activity, by administering a prophylactically or therapeutically effective amount of particulate, bioavailable β(1,3; 1,6) glucan. The invention also relates to methods in which β(1,3; 1,6) glucan is provided ... 11/03/05 - 20050245479 - Myeloglycan Systematic chemical analysis of glycosphingolipid (GSL) fractions from large quantities of normal human neutrophils and HL60 cells failed to detect GSL's which are binding targets of selectin. A series of long-chain, unbranched polylactosamine GSL's with a terminally sialylated, internally polyfucosylated structure bind selectins. ... 10/27/05 - 20050239743 - Compositions and methods to inhibit restenosis Disclosed herein are compositions and methods comprising a polysaccharide in combination with a pharmaceutical agent wherein the composition can be used to prevent restenosis. ... 10/27/05 - 20050239742 - Carrageenan-based formulations and associated methods of use A method is provided for treating a female individual who suffers from or is prone to dyspareunia. The method involves vaginal and/or vulvar administration of a formulation comprising a therapeutically effective amount of a carrageenan and a pharmaceutically acceptable aqueous carrier. In addition, a carrageenan-based formulation is provided as a ... 10/27/05 - 20050239741 - Novel synthetic ganglioside derivatives and compositions thereof Novel synthetic gangliosides and pharmaceutical compositions containing such synthetic gangliosides are described. Methods of making the novel synthetic ganglioside compounds and compositions as well as their use in the field of neuroprotection and cancer treatment is also described. ... 10/20/05 - 20050234014 - O-sulphated bacterial polysaccharides and their use The present invention refers to the preparation of O-sulphated, N-sulphatated or N-acetylated derivatives, both epimerised or non epimerised, of K5, K4, and optionally defructosilated K4 and K40 polysaccharides and to their use as antiinflammatory agents in chronic and acute inflammations. ... 10/20/05 - 20050234013 - Novel interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis The present invention relates to a disorder of the lower urinary tract, and in particular, reducing the symptoms (including treatment) of interstitial cystitis in vivo. In a preferred embodiment, the present invention relates to treatment formulations and methods for reducing interstitial cystitis in patients. ... 10/20/05 - 20050234012 - Combinations of viscoelastics for use during surgery An improved viscoelastic composition useful in the performance of ophthalmic surgical procedures and especially cataract procedures is disclosed. The embodiments of the composition comprise combinations of sodium hyaluronate and chondroitin sulfate and exhibit an improved rheological profile. ... 10/20/05 - 20050234011 - Re-epithelializing pharmaceutical compositions comprising xanthan gum The present invention relates to the use of xanthan gum as re-epithelializing agent and, in particular, to a pharmaceutical formulation comprising xanthan gum as a re-epithelializing active principle eventually mixed with hyaluronic acid. Said use and composition speed up and improve advantageously the formation of newly grown epithelium. ... 10/20/05 - 20050234010 - Novel branched sialo-sugar molecules and antiviral agents using the same (wherein NeuAc represents N-acetylneuraminic acid in which the hydroxyl group, the carboxyl group and the amido group may be chemically modified with a halogen group, an alkyl group or an acyl group, either the same group or separate groups, Hex represents hexose, HexNAc represents N-acetylhexosamine and R represents a substrate ... 10/13/05 - 20050227943 - Certain aminoalkyl glucosaminide phosphate compounds and their use Compounds that are adjuvants and immunoeffectors are described and claimed. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Compositions and methods for using the compounds as adjuvants and immunoeffectors are also disclosed. ... 10/13/05 - 20050227942 - Method and agent for the prevention, inhibition and treatment of sepsis The invention relates to the use of Asialo-Gm1 (Agm1) and/or GM gangliosides, and substances which simulate the carbohydrate part of said gangliosides in terms of binding to anti-AGm1 antibodies and/or anti-Gm1 antibodies, for producing an agent which blocks or binds to anti-AGm1 antibodies and/or anti-Gm1 antibodies which bind to natural ... 10/13/05 - 20050227941 - Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases The present invention describes a method of administering an Aβ-binding agent or drug which has affinity for amyloid beta (Aβ) in the periphery (blood) and reducing Aβ levels in the brain without the need for the agent or drug to enter the brain itself. The Aβ-binding agents utilized in the ... 10/06/05 - 20050222083 - Thiol-modified hyaluronan The present invention relates to biscarbodiimides, thiourea derivatives, urea derivatives, and cross-linked hyaluronan derivatives having at least one intramolecular disulfide bond, and methods of preparation thereof. The invention also includes thiolated hyaluronan derivatives and salts thereof having at least one pendant thiol group or a modified pendant thiol group, and ... 10/06/05 - 20050222082 - Agent for producing a sensation of safety and for weight loss The present invention pertains to an improved agent for producing a satiety effect and for weight loss. The agent according to the invention is also suitable for regulating the cholesterol balance. ... 10/06/05 - 20050222081 - Cross-linked hyaluronate compounds There is disclosed a cross-linked hyaluronate compound obtained by reacting a sodium hyaluronate compound with a polfunctional aziridine compound as a cross-linking agent. The polyfunctional aziridine compound was added to hyaluronan of various molecular weights in an equivalent ratio of HA/AZ of 1:1 to 1:10, preferably, 1:3 to 1:10, more ... 10/06/05 - 20050222080 - Cycloglycans suitable to inhibit mammalian infection Described is the use of in particular homopolymer cycloglycans having a ring-shaped base structure of 2 to 40 monosaccharides in the ring, for preventing the invasion and infection of mammal cells by pathogens, and for combating diseases caused by such pathogens, and food compositions, dietetic compositions and pharmaceutical compositions containing ... 09/29/05 - 20050215518 - Glycosaminoglycans derived from k5 polysaccharide having high anticoagulant and antithrombotic activities and process for their preparation Glycosaminoglycans derived from K5 polysaccharide having high anticoagulant and antithrombotic activity and useful for the control of coagulation and as antithrombotic agents are obtained starting from an optionally purified K5 polysaccharide by a process comprising the steps of N-deacetylation/N-sulfation, C5 epimerization, O-oversulfation, selective O-desulfation, 6-O-sulfation, N-sulfation, and optional depolymerization, in ... 09/29/05 - 20050215517 - Use of an anti-endotoxin drug in the prevention and treatment of disease The invention provides methods for preventing and treating disease involving the use of an anti-endotoxin drug. ... 09/29/05 - 20050215516 - New free-radical scavenger containing viscoelastic composition, methods of use and package The present invention is directed to a viscoelastic composition comprising an aqueous solution having a minimum of about 0.01% w/v and a maximum of about 20% w/v of a viscoelastic polymer based upon the total volume of the viscoelastic composition. Typically, the viscoelastic composition further contains tris[hydroxymethyl]aminomethane and a polyol ... 09/29/05 - 20050215515 - Viscoelastic composition, method of use and package The present invention is a viscoelastic composition, methods of use and a related device, wherein the viscoelastic composition comprises water, a minimum of about 0.01% w/v and a maximum of about 10% w/v of hyaluronic acid or a salt thereof and a minimum of about 0.01% w/v and a maximum ... 09/22/05 - 20050209188 - Methods using glycosaminoglycans for the treatment of nephropathy The present invention relates to a method for the treatment of HIV-associated nephropathy by administration of glycosaminoglycans, and in particular, by the administration of sulodexide. ... 09/15/05 - 20050203057 - Treatment of cancers Methods for treating a cancer in a subject are described that include administering N-glycolylneuraminic acid or a derivative thereof to the subject. ... 09/15/05 - 20050203056 - Carboxyl-reduced derivatives of hyaluronic acid, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them in which R or R1 represents H or SO3M, n is an integer of between 0 and 25 000, M is an alkali metal, isolated or as mixtures, to the diastereoisomers thereof, to the process for the preparation thereof, to the uses thereof as a medicinal product and to the ... 09/15/05 - 20050203055 - Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections A method for treating and preventing various infections, including papilloma virus and fungal and parasitic infections is provided. In particular, an effective amount of a sulphated polysaccharide, such as cellulose sulphate and dextran sulphate are administered to prevent and treat these infections. The invention also relates to use of these ... 09/15/05 - 20050203054 - Use of lipid conjugates in the treatment of diseases wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, X is a physiologically acceptable monomer, dimer, oligomer, or polymer, wherein X is a glycosaminoglycan; and ... 09/08/05 - 20050197318 - Fucose containing proteoglycan or acidic glycan and their pharmaceutical use A class of proteoglycans containing fucosylated acidic glycans, e.g., as produced by marine sponges and sea urchin embryos, have been found to stimulate selective proliferation of mammalian natural killer (NK) cells and γδT cells. These compounds are useful as pharmaceuticals, particularly as immunostimulants, e.g., in the treatment of cancer and ... 09/01/05 - 20050192251 - Water soluble bioactive fraction isolated from gum resin exudate of boswellia serrata, process for isolation thereof composition containing said fraction and use thereof The present invention relates to a water-soluble bioactive fraction obtained from the gum resin exudate of Boswellia serrata and to a process for the preparation thereof. The present invention also relates to a process for the isolation of a water soluble bioactive fraction containing a mixture of potassium and calcium ... 09/01/05 - 20050192250 - Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants. ... 09/01/05 - 20050192249 - Room temperature stable agarose solutions Room temperature stable, non-gelling polysaccharide solutions such as agaroses, dextrans and cyclodextrans are made by the present invention. It has been found that by incorporating certain gel-inhibiting additives into an aqueous polysaccharide solution, the gel point is reduced or eliminated and the solution remains liquid at room temperature indefinitely. Additives ... 09/01/05 - 20050192248 - Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases The present invention relates to methods and compositions for augmenting an immunogenicity of an antigen in a mammal, comprising administering said antigen together with an adjuvant composition that includes a synthetic glycolipid compound of Formula I, as described herein. According to the present invention, the use of a compound of ... 08/25/05 - 20050187187 - Carboxyl-reduced derivatives of chondroitin sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them in which R1, R2, R3 and R4 are H or SO3M, n is an integer of between 0 and 200, M is an alkali metal, isolated or as mixtures, to the diastereoisomers thereof, to the process for the preparation thereof, to the uses thereof as a medicinal product and to ... 08/25/05 - 20050187186 - Pharmaceutical compositions of safingol and methods of using the same The present invention provides stable aqueous solutions consisting essentially of: (a) a sphingolipid; (b) lactic acid; and (c) optionally a stabilizing agent; wherein the solution has a molar ratio of lactic acid to sphingolipid of 1:1 to 10:1. The present invention further provides an emulsion formulation consisting essentially of: (a) ... 08/25/05 - 20050187185 - Pharmaceutical applications of hyaluronic acid preparations The invention relates to novel applications of pharmaceutical compositions containing preferably long-chain hyaluronic acids which are cross-linked or not cross-linked, and conventional adjuvants and/or supporting materials. ... 08/18/05 - 20050182022 - Chondroprotective/restorative compositions and methods of use thereof The instant invention provides a method of treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery, deterioration of proper joint function including joint mobility, the reduction or inhibition of metabolic activity of chondrocytes, the activity of enzymes that degrade cartilage, the reduction or ... 08/18/05 - 20050182021 - Polysaccharide alcohol antiseptic gel An alcohol-based composition for sanitizing surfaces has persistent sanitizing properties after evaporation of the alcohol. The composition includes a cationic polysaccharide, an organic acid, alcohol, and water. The cationic polysaccharide can be chitosan, cationic guar or cationic starch. The cationic polysaccharide can be complexed with a transition metal, such as ... 08/18/05 - 20050182020 - Ceramide de novo synthesis-based therapeutic and prophylactic methods, and related articles of manufacture Described is a method for decreasing the amount of mSREBP in a cell characterized by an elevated level of mSREBP comprising contacting the cell with an agent that specifically inhibits de novo synthesis of ceramide in the cell, thereby decreasing the amount of mSREBP in the cell. Also described are ... 08/11/05 - 20050176678 - Compounds and method for coating surfaces in a haemocompatibe manner The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic ... 08/11/05 - 20050176677 - Cosmetic composition comprising monosaccharides or polysaccharides, uses and treatment methods A cosmetic and/or dermatological composition includes comprising, as an active ingredient, at least one mono or polysaccharide, constitutive of a pectic substance coming from a plant of the Lemnaceae family. The invention includes also its use, inter alias, for the care of the skin and/or its appendages, its use in ... 08/04/05 - 20050171054 - Novel method and composition for local treatment of meniere's disease, tinnitus and/or hearing loss Novel methods and compositions for the local treatment of Meniere's disease, tinnitus and hearing loss employ a therapeutically effective amount of a prostaglandin of the F-type to the inner ear. The treatment can be either continuous or intermittent and may involve the use of pumps, gels, or slow release drug ... 08/04/05 - 20050171053 - Carrageenan based antimicrobial compositions Disclosed are compositions for inhibiting transmission of a sexually transmitted infection that contain one or more carrageenans, including lambda carrageenan. Also disclosed are methods for making and using the compositions. ... 07/28/05 - 20050164984 - Chondroitin synthase gene and methods of making and using same The present invention relates to a chondroitin synthase gene and methods of making and using same. In more particular, but not by way of limitation, the present invention relates to a chondroitin synthase gene from Pasteurella multocida and methods of isolating and using same. Additionally, the present invention relates to ... 07/28/05 - 20050164983 - Carboxyl-reduced derivatives of dermatan sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them in which R1, R2, R3 or R4 represents H or SO3M, n is an integer of between 0 and 150, M is an alkali metal, isolated or as mixtures, to the diastereoisomers thereof, to the process for the preparation thereof, to the uses thereof as a medicinal product and to ... 07/28/05 - 20050164982 - Specific antagonist for both e- and p-selectins Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a particular glycomimetic linked to a particular BASA (Benzyl Amino ... 07/28/05 - 20050164981 - Biological lubricant composition and method of applying lubricant composition Fluid compositions and methods for lubrication of mammalian joints are disclosed, including both natural and artificial fluids. Synovial fluid acts to lubricate the bearing surfaces of bones and bone-like structures which are held in frictional contact within biological joints. Such fluids may be used to treat arthritic, injured, and diseased ... 07/28/05 - 20050164980 - Hyaluronic acid modification product The present invention provides a safe hyaluronic acid base material that is suitable for use in practical hyaluronic acid pharmaceutical preparations capable of distribution at room temperature and having such a low viscosity that injection is easy. The hyaluronic acid pharmaceutical preparations can reside in a joint cavity for a ... 07/28/05 - 20050164979 - Pharmaceutical composition for ophthalmological and rhinological application The invention concerns a pharmaceutical composition which contains at least panthenol and/or pantothenic acid and hyaluronic acid and/or hyaluronate and optionally additionally pharmaceutical auxiliary agents. The invention further concerns the use of the pharmaceutical composition for the treatment of ophthalmological and/or rhinological malfunctions. ... 07/21/05 - 20050159390 - Treatment and prevention of hiv and other viral infections Methods for preventing or treating a viral infection in a subject are described that include administering N-glycolylneuraminic acid or a derivative thereof to the subject. ... 07/14/05 - 20050153929 - Use of an anti-endotoxin drug in the prevention and treatment of disease The invention provides methods for preventing and treating disease involving the use of an anti-endotoxin drug. ... 07/14/05 - 20050153928 - Conjugates comprising a central nervous system-active drug linked to glucuronic acid or glucosamine through an amide bond and uses thereof Disclosed are conjugates comprising a central nervous system-active drug linked through an amide bond to a glucuronic acid or glucosamine moiety, and uses thereof, e.g., for treating or ameliorating central nervous system diseases or disorders. ... 07/07/05 - 20050148541 - Treatment and prevention of hiv and other viral infections Methods for preventing or treating a viral infection in a subject are described that include administering N-glycolylneuraminic acid or a derivative thereof to the subject. ... 06/30/05 - 20050143342 - Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections The invention relates to the treating, inhibiting or preventing of certain infectious agents including papilloma virus and various vaginitis-causing microbes by employing cellulose sulfate and other sulfated polysaccharides. In one embodiment, the method involves preventing, inhibiting or treating fungal infections. Corresponding methods of use in manufacturing a medicament as well ... 06/23/05 - 20050137166 - Use of cooling agents to relieve mild ocular irritation and enhance comfort Ophthalmic compositions containing very low concentrations (e.g., 1 to 50 ppm) of cooling agents are described. The cooling agents are less volatile and less prone to causing ocular discomfort than agents previously utilized to obtain an ocular cooling effect, such as menthol. The cooling agents are preferably contained in a ... 06/23/05 - 20050137165 - Methods for cell mobilization using in vivo treatment with hyaluronan (ha) The use of forms of hyaluronic acid having a molecular weight less than about 750,000 daltons selected from the group consisting of hyaluronic acid and pharmaceutically acceptable salts thereof is provided for the same purposes known for using recombinant GM-CFS of G-CSF. ... 06/23/05 - 20050137164 - Diclofenac compositions for the treatment of skin disorders Novel NSAID pharmaceutical compositions and methods for the treatment of skin disease and disorders such as actinic keratosis using same are disclosed. ... 06/23/05 - 20050137163 - Modified hyaluronic acid for use in musculoskeletal tissue repair The present invention includes hyaluronic acid complexes of a monovalent alkali metal salt of hyaluronic acid and a tetra alkyl ammonium halide that are suitable for incorporation with tissue scaffolds that are suitable for use in repair and/or regeneration of muscoloskeletal tissue and that include a biodegradable, porous substrate made ... 06/16/05 - 20050130934 - Antibacterial agents and process for producing the same An antibacterial agent showing a high affinity for Helicobactor pyroli and having an antibacterial effect specific to H. Pyroli. The agent has a chemical structure wherein an antibacterial substance is bonded to a sulfated polysaccharide or an oligosaccharide prepared by partial decomposition of the sulfated polysaccharide. Preferable embodiments are those ... 06/16/05 - 20050130933 - Weight-loss supplement A weight-loss supplement comprising a satiety-promoting ingredient that includes a mixture of dietary fibers comprising glucomannan and a gum and; a thermogenic ingredient selected from the group consisting of caffeine, catechin-polyphenol and combinations thereof. ... 06/16/05 - 20050130932 - Solutions and films of glycated chitosan Preparations containing glycated chitosan in a physiologically compatible carrier are described. Viscoelastic preparations comprise 1.0-12.0 percent by weight of glycated chitosan in an aqueous solution while lower viscosity solutions possess 0.1-0.5 percent by weight glycated chitosan. The otherwise free amino groups of the chitosan polymer are preferably 30-90% glycated and ... 06/09/05 - 20050124576 - Composition and method A composition suitable for mammalian oral ingestion in a mammal having GI tract inflammation comprising an anti-diarrhea effective amount of glutamine, fermentable fiber(s), antioxidant(s), and omega-3 fatty acid(s). ... 06/09/05 - 20050124575 - Remedies Remedies or |