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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > O-glycoside > > Oxygen Of The Saccharide Radical Bonded Directly To A Nonsaccharide Hetero Ring Or A Polycyclo Ring System Which Contains A Nonsaccharide Hetero Ring > The Hetero Ring Has 8 Or More Ring Carbons > The Hetero Ring Has Exactly 13 Ring Carbons (e.g., Erythromycin, Etc.)

The Hetero Ring Has Exactly 13 Ring Carbons (e.g., Erythromycin, Etc.)

The Hetero Ring Has Exactly 13 Ring Carbons (e.g., Erythromycin, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

01/18/07 - 20070015719 - Nanoparticulate clarithromycin formulations
The present invention is directed to compositions comprising nanoparticulate macrolides such as clarithromycin, or a salt or derivative thereof, having improved bioavailability. The nanoparticulate macrolide particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the treatment of infection and ...

12/28/06 - 20060293261 - Clarithromycin or a salt thereof for the treatment or prevention of pulmonary disorders caused by the destruction of pulmonary alveoli
For the purpose of treatment and/or prevention of pulmonary disorders caused by the destruction of pulmonary alveoli resulting from smoking, air pollution, noxious gas, etc., there are provided, among others, a method of administering clarithromycin or a salt thereof to a mammal and a pharmaceutical composition comprising clarithromycin or a ...

11/30/06 - 20060270616 - Motilide compounds
where RA, RB, RC, RD, RE, and RF are as defined herein, are useful as prokinetic agents. ...

11/23/06 - 20060264387 - Macrolides
with improved activity, to medicaments comprising such antibiotics, and to the use of such antibiotics for the treatment of infectious diseases, inflammatory diseases and human diseases or disorders which can be ameliorated by inhibition human phospdiesterases. ...

08/31/06 - 20060194748 - Methods for treating disorders induced by h. pylori infections and pharmaceutical compositions for the same
The present invention provides a pharmaceutical composition for the treatment of disorders induced, caused, and/or mediated by Helicobacter pylori infection, as well as methods of treating the same by administering the pharmaceutical composition of the present invention. ...

08/24/06 - 20060189552 - Dispenser for dispensing three or more actives
Two separate compositions, one containing an effective anti-acne treating amount of a first active ingredient and one containing a second active ingredient that is incompatible with the first active ingredient are packaged within and dispensed from a common dispenser. By packaging these two active ingredients in this manner, long shelflife ...

08/03/06 - 20060172955 - Antibiotic/benzoyl peroxide dispenser
Two separate compositions, one containing an effective anti-acne treating amount of a first active ingredient and one containing a second active ingredient that is incompatible with the first active ingredient are packaged within and dispensed from a common dispenser. By packaging these two active ingredients in this manner, long shelflife ...

07/27/06 - 20060166906 - 6-o-substituted erythromycin derivatives having improved gastrointestinal tolerance
are useful for treating bacterial infections while avoiding the concomitant liability of gastrointestinal intolerance. Compositions containing the compounds and methods of treatment using the compounds are also disclosed. ...

04/06/06 - 20060074032 - Synthesis and separation of optically active isomers of erythromycin and their biological actions
The present invention provides methods for purifying and using optically active isomers of erythromycin as well as compositions comprising such optically active isomers. Such optically active isomers having desired actions as an antibiotic substantially separable from undesirable effects on GI motility and the cardiac potassium channels such that the cardiac ...

03/23/06 - 20060063725 - Process of preparing a crystalline azithromycin monohydrate
The present invention provides a process of preparing a crystalline azithromycin monohydrate. The process involves dissolving azithromycin in a solution containing ethanol, adding the dissolved azithromycin into water to precipitate the crystals, isolating and drying the precipitate to a water content of about 5% (w/w) to about 7% (w/w). The ...

03/16/06 - 20060058248 - Processes for the preparation of 6-11 bicyclic erythromycin derivatives
The present invention relates to processes and intermediates for the preparation of 6-11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (IX-c): ...

02/02/06 - 20060025357 - Use of agent for suppressing infection and proliferation of human immunodeficiency syndrome virus
The present invention relates to agent for suppressing infection and proliferation of human immunodeficiency syndrome virus (HIV-1), which infects immunocompetent cells such as macrophage or dendritic cell and causes destruction of immune system, and use of known compounds, macrolide derivatives for suppression of infection and proliferation of human immunodeficiency syndrome ...

02/02/06 - 20060025356 - 28-epirapalogs
Methods and materials involving 28-epirapamycin analogs are disclosed. ...

12/22/05 - 20050282758 - 6-11 bicyclic ketolide derivatives
which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ...

12/08/05 - 20050272673 - Pharmaceutical combination and method for treatment of reactive arthritis or bursitis
A method for treatment for conditions in human beings associated with either or both reactive arthritis or bursitis comprising administering a combination of a member from each of the following groups of medications: (1) synthetic purine nucleoside analog antiviral drugs, (2) antibiotic drugs, and (3) imidazole drugs. Alternate embodiments of ...

12/08/05 - 20050272672 - Ketolide anti-infective compounds
and R1, R2, R3 R4, and R5 are as defined herein, are useful as anti-infective agents. ...

12/01/05 - 20050267054 - Antibacterial compounds with improved pharmacokinetic profiles
and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis and treatment of bacterial infections using the compounds are disclosed. ...

11/17/05 - 20050256064 - 9-desoxoerythromycin compounds as prokinetic agents
wherein R1, R2, R3, R4, and R5 are as defined herein, are useful as prokinetic agents for treating disorders of gastric motility. ...

// - 9-Desoxoerythromycin compounds of formula I -
...

11/10/05 - 20050250714 - Crystalline forms of 9-(s)-erythromycylamine
The present invention provides novel crystalline forms of the macrolide antibiotic 9-(S)-erythromycylamine, and methods of preparing and using the same. ...

11/10/05 - 20050250713 - 11,12-cyclic thiocarbamate macrolide antibacterial agents
The present invention is directed to novel macrolide antibacterial agents and processes for preparing them. The present invention is further directed to pharmaceutical compositions containing the novel macrolide antibacterial agents disclosed herein and their use in the treatment and prevention of bacterial infections. ...

07/21/05 - 20050159371 - Process for producing erythromycin a derivative
An efficient process for producing an 11,12-cyclic carbamate 6-O-substituted ketolide derivatives having the natural stereochemistry at the 10-position. ...

07/14/05 - 20050153905 - Novel ketolide derivatives
as well as pharmaceutically acceptable salts, esters or prodrugs thereof, pharmaceutical compositions comprising such compounds, methods of treating bacterial infections by the administration of such compounds, and processes for the preparation of the compounds. ...

06/30/05 - 20050143326 - 11-c-substituted erythromycin derivatives
which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ...

06/02/05 - 20050119195 - N-desmethyl-n-substituted-11-deoxyerythromycin compounds
wherein R1, R2, R3, R4, R5, and R6 are as defined herein, are prokinetic agents and can be used to treat disorders of gastric motility. ...



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