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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > O-glycoside > > Oxygen Of The Saccharide Radical Bonded Directly To A Nonsaccharide Hetero Ring Or A Polycyclo Ring System Which Contains A Nonsaccharide Hetero Ring > The Hetero Ring Has 8 Or More Ring Carbons The Hetero Ring Has 8 Or More Ring CarbonsThe Hetero Ring Has 8 Or More Ring Carbons patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.01/25/07 - 20070021359 - Addition salts of azithromycin and citric acid and process for preparing them Said addition salts have a molar ratio between azithromycin and citric acid such as to provide a pH comprised between 4.0 and 8.0 in a 10% aqueous solution. The process for preparing said salts comprises: a) dissolving azithromycin in a solvent or mixture of solvents; b) adding citric acid; and ... 01/18/07 - 20070015718 - Diagnosis and management of infection caused by chlamydia The present invention provides a method of treating coronary artery disease in a patient in need thereof by administering to the patient an antichlamydial amount of a rifamycin for a duration to treat said coronary artery disease. ... 01/11/07 - 20070010464 - Avermectin and praziquantel combination therapy An antiparasitic combination therapy compising a combination of a 13-monosaccharide 5-oxime avermectin, such as selamectin, and praziquantel in a veterinarily acceptable carrier, diluent or adjuvant. Also provided is a method of treatment or prophylaxis of a parasitic infestation as well as a kit useful in the treatment or prophylaxis of ... 01/11/07 - 20070010463 - Remedies for diseases caused by strengthened vascular smooth muscle using 14-membered ring macrolid compounds It is intended in this invention to provide novel preventives/remedies for diseases caused by the growth of vascular smooth muscles, for example, re-occlusion occurring after a ballon-dilation treatment for cardiac coronary occlusion. Namely, vascular smooth muscle growth inhibitors, cyclin-dependent kinase complex expression enhancers, preventives/remedies for diseases caused by the growth ... 12/28/06 - 20060293260 - Useful high load concentrate compositions for control of ecto-and endo-parasites High load concentrate compositions comprising metaflumizone, a substantially water-insoluble anti-parasitic macrolide compound,such as moxidectin, an optional bridging agent, a surfactant, and a suitable carrier solvent are prepared. These compositions may be topically administered to animals, and are useful for preventing or treating ectoparasitic infestations in warm-blooded animals for prolonged periods ... 12/14/06 - 20060281695 - Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives Methods for treating an animal for endo and/or ecto parasite infestation and/or for protecting an animal from endo and/or ecto parasite infestation using N-phenyl-1,1,1-trifluoromethanesulfonamide compounds are provided, together with methods of making the same compounds, and methods of using the same compounds to treat parasite infestations in vivo or ex ... 11/23/06 - 20060264386 - Pharmaceutical formulations of 6-11 bicyclic ketolide derivatives and related macrolides and methods for preparation thereof The present invention provides pharmaceutical compositions and solid formulations comprising EP-013420 of form I, form II, form Ia, amorphous form and monohydrate and the methods of formulation preparations. The present invention provides methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment. ... 11/23/06 - 20060264385 - Bifunctional heterocyclic compounds and methods of making and using same The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents. ... 11/16/06 - 20060258600 - Ether linked macrolides useful for the treatment of microbial infections and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body. ... 11/09/06 - 20060252713 - Spirocyclic bicyclolides which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 11/09/06 - 20060252712 - 6-11 bridged oxime erythromycin derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 11/09/06 - 20060252711 - Method and medicament for treating ocular infections The invention relates to a method for treating ocular infections, by topical application twice a day in each eye to be treated, for less than four days, of a medicament essentially consisting of azithromycin in solution in a pharmaceutically acceptable vehicle of linear medium-chain fatty acid triglycerides, at the concentration ... 11/09/06 - 20060252710 - 6-11 bridged oxime erythromycin derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 11/09/06 - 20060252709 - Novel semisynthetic macrolide antibiotics of the azalide series The invention relates to N″-substituted 9a-N-(N′-carbamoyl-γ-aminopropyl), 9a-N-(N′-thiocarbamoyl-γ-amino-propyl), 9a-N-[N′-((β-cyanoethyl)-N′-carbamoyl-γ-aminopropyl] and 9a-N-[N′-((β-cyanoethyl)-N′-thiocarbamoyl-γ-aminopropyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-0-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A, novel semisynthetic macrolide antibiotics of the azalide series, of the general formula 1, wherein R represents H or cladinosyl moiety, R1 represents H or (β-cyanoethyl moiety, R2 represents isopropyl, 1-naphtyl, 2-naphtyl, benzyl, 2-(trifluommethyl)phenyl, ... 11/02/06 - 20060247184 - Treatment and prophylaxis of diseases and infections pigs and poultry The use of AIVLOSIN, as such or as a pharmaceutically acceptable (non-toxic) derivative such as an acid addition salt, for the preparation of a veterinary medicament for the treatment and prophylaxis of diseases and infections of pigs and poultry. In particular, the diseases and infections treatable are necrotic enteritis in ... 10/26/06 - 20060241061 - Stable aqueous solution of natamycin fungicide The present invention provides an aqueous composition comprising—water; —a water miscible solvent; —and a polyene fungicide which is dissolved in the water and water miscible solvent. The present invention further provides a method for the production of the composition of the invention. The composition of the invention may be used ... 10/26/06 - 20060241060 - 10-substituted macrolide antibiotics The invention provides antibiotic 10-desmethyl macrolides. ... 10/19/06 - 20060234959 - Photodynamic therapy utilizing multiple duty cycle light modulation A method of photodynamic disruption of target cells within a target cell site wherein the target cells are associated with one or more of a sterilization procedure, a biofilm eradication procedure, a sterilization procedure of a medical prosthesis, a treatment of an infection at a tissue site, eradication of cancer ... 10/19/06 - 20060234958 - Process of increasing cellular production of biologically active compounds A process of increasing the cellular production of biologically active compounds is provided. The process is particularly useful for increasing antibiotic production by bacterial cells. The process includes the step of inhibiting the activity of methylmalonyl-CoA mutase. ... 10/12/06 - 20060229263 - Avermectin b1 monosaccharide derivatives A compound of formula (I) wherein the bond between carbon atoms 22 and 23 may be a single or a double bond; R1 is C1-C12alkyl, C3-C8cycloalkyl, or C2-C12alkenyl; R2 and R3 are, for example, independently of each other hydrogen, C1-C12alkyl, C3-C12cycloalkyl, C2-C12alkenyl, C2-C12alkynyl, aryl or heteroaryl; and, where applicable, to ... 09/21/06 - 20060211636 - Macrolide antibiotics The present invention relates to 11,12 γ lactone ketolides of formula (I) wherein R, R1, R2, R3 are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or ... 09/14/06 - 20060205683 - Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same The present invention relates to processes for preparing protected silylated clarithromycin oxime, preferably 6-O-methyl-2′, 4″-bis(trimethylsilyl)-erythromycin A 9-O-(2-methoxyprop-2-yl)oxime (“S-MOP oxime”), and for converting protected silylated clarithromycin oxime, preferably S-MOP oxime, to clarithromycin. Processes for preparing protected silylated clarithromycin oxime according to the present invention, include reacting a silyl oxime derivative with ... 09/14/06 - 20060205682 - Antibiotic and combinations of antibiotic and symptomatic relief agent formulations Disclosed herein are antibiotic formulations and combinations of antibiotic and symptomatic relief agent formulations. The combinations are suitable to treat a variety of diseases, including an infection, while treating the symptoms associated with the disease. Also disclosed are methods of treating a disease or an infection and its symptoms, as ... 09/14/06 - 20060205681 - Homogenous paste formulations This invention provides for a pharmaceutical or veterinary paste formulation comprising: an effective amount of a therapeutic agent; fumed silica; an absorbent and a viscosity modifier; optionally a hydrophilic carrier and optionally, a colorant, stabilizer, surfactant, or preservative and methods of preparing these formulations. This invention also provides for, inter ... 09/14/06 - 20060205680 - Fungicidal agent combinations and active compounds listed in the disclosure. ... 08/31/06 - 20060194747 - Synergistic insecticidal mixtures and at least one further known active compound selected from the group consisting of β-cyfluthrin and lambda-cyhalothrin. ... 08/24/06 - 20060189551 - Combination therapies for fungal pathogens The present invention relates to methods of treating fungal infections with a drug combination: a first compound that inhibits the activity or expression of the protein FKBP12 and a second compound that inhibits the activity or expression of homoserine dehydrogenase. Evidence indicates that dual inhibitors of proteins FKBP12 and homoserine ... 08/17/06 - 20060183697 - Complexing of medicinal substances with high-molecular carriers and injection and infusion solutions containing said complexes A molecular complex of a high molecular weight carrier substance and of a medicinal substance. The carrier substance has functional groups whereby the carrier substance and the medicinal substance are bound non-covalently. The medicinal substance is insoluble or slightly soluble in water and the carrier substance is readily soluble in ... 07/27/06 - 20060166905 - Aivlosin for the treatment of disease due to brachyspira pilosicoli or ornithobacterium rhinotracheale The invention relates to the use of Aivlosin for the treatment, prevention or control of diseases due to Brachyspira pilosicoli in pigs and Ornithobacterium rhinotrachelae in poultry. ... 07/27/06 - 20060166904 - 9a-azalides with anti-inflammatory activity Macrolides with anti-inflammatory activity are described, and more particularly, 9a-azalides without cladinose in position 3 with anti-inflammatory activity, their pharmaceutically acceptable salts and pharmaceutical compositions that contain them as active principle. ... 07/13/06 - 20060154881 - 9a,11-2c-bicyclic 9a-azalide derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 07/13/06 - 20060154880 - Methods and compositions using immunomodulatory compounds for treatment and management of parasitic diseases Methods of treating, preventing and/or managing various protozoan parasitic disease and disorders are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone, or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with conventional anti-parasitic treatments ... 07/13/06 - 20060154879 - Avermectins substituted in the 4 and 4'-positions having pesticidal properties What is described are a compound of the formula (I) Wherein A-B is —CH═CH— or —CH2—CH2—; n is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 and R3 for instance are either, (i) independently from each other for instance -Q, —C(═Y)-Q, or —C(═Y)—O-Q; or (ii) together form with ... 07/13/06 - 20060154878 - New 3-decladinosyl derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin a 9a, 11-cyclic carbamates The present invention relates to the new 3-decladinosyl derivatives of 9-de-oxo-9a-aza9a-homoerythromycin A 9a,11-cyclic carbamate of the general formula (I), their pharmaceutically acceptable addition salts with inorganic or organic acids and their hydrates, wherein R1 individually stands for hydrogen, hydroxyl or a group of the formula (II), wherein X individually stands ... 07/06/06 - 20060148731 - 11,12-lactone bicyclolides which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 07/06/06 - 20060148730 - Method of treating tuberculosis Macrolide and ketolides, and compositions containing the same, useful in the treatment of tuberculosis are disclosed. Methods of treating tuberculosis using the macrolides and ketolides, and compositions containing the same, also are disclosed. ... 07/06/06 - 20060148729 - Avermectin b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substitutent in the 4-or 4'-position What is described are a compound of the formula (I): wherein n is 0 or 1; A-B is —CH═CH— or —CH2—CH2—; R1 is C1-C12-alkyl, C3-C8-cycloalkyl or C2-C12-alkenyl; R2 is for example C1-C12-alkyl, C2-C12-alkenyl or C2-C12-alkinyl; which are optionally substituted with one to five substituents selected from the group consisting of ... 06/29/06 - 20060142216 - Parasiticidal composition An anti-parasiticidal composition presented as a topical “pour-on” product for treating animals infected by parasites which are known to be susceptible to salicylanilides, especially closantel, alone or together with at least one other anti parasitic compound of the avermectin or milbemycin type and offers enhanced bioavailability of the salicylanilide by ... 06/29/06 - 20060142215 - Tetracyclic bicyclolides which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 06/29/06 - 20060142214 - 3,6-bicyclolides which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 06/22/06 - 20060135447 - Macrolides Also disclosed are methods of preparing the compounds, intermediates, and pharmaceutical compositions thereof, and methods of treating or preventing disease by administering the compounds to subjects in need. This abstract is only an excerpt and is not limiting of the invention. ... 06/15/06 - 20060128642 - 9-ketospinosyn derivatives The present invention relates to derivatives of 9-keto spinosyns, which are substituted by a ═N—(O, NH or NRx)—Ry moiety in the C-9 position, to methods for their manufacture, and to their use for controlling animal pests. ... 06/15/06 - 20060128641 - Levamisole, avermectins or similar in pyrrolidone solvent A stable formulation which is suitable for administration to animals is claimed. The formulation includes at least one active selected from the group comprising avermectins and milbemycins and levamisole. Both of the actives are dissolved in a pyrrolidone solvent. ... 06/08/06 - 20060122128 - 3,6-bicyclolides which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 06/01/06 - 20060116336 - Lyophilized azithromycin formulation The invention provides among other things a stable, sterile pharmaceutical formulation comprising lyophilized azithromycin and ethanol. The invention also provides a method of producing a stable, sterile pharmaceutical product comprising lyophilized azithromycin. The invention also provides a pharmaceutical dosage form comprising the pharmaceutical formulation, as well as a method of ... 06/01/06 - 20060116335 - Ready-for-complexation composition The invention relates to a ready-for-complexation (RFC) composition, comprising a polyene antimycotic and a cyclodextrin or the derivatives thereof. Also disclosed is a method of using the ready-for-complexation (RFC) composition of the invention to improve the solubility of polyene antimycotic. ... 05/25/06 - 20060111309 - Chalcomycin derivatives The invention relates to novel chalcomycin derivatives, medicaments containing said derivatives or the salts thereof, and the use of chalcomycin derivatives for treating diseases, especially infections. The inventive chalcomycin derivatives are acylated on the sugar esters and derivatives are also acylated on the 9-carbonyl function. ... 05/18/06 - 20060105971 - Salts of avermectins substituted in the 4-position and having pesticidal properties with the proviso that R1 is not sec-butyl or isopropyl when R2 is H and R3 is methyl; and, where applicable, their possible tautomers; a process for the preparation of those compounds and their tautomers and the use thereof; pesticidal compositions in which the active ingredient has been selected from ... 05/18/06 - 20060105970 - Avermectins substituted in the 4-position having pesticidal properties with the proviso that R1 is not sec-butyl or isopropyl if R2 is H and R3 is 2-hydroxyethyl, isopropyl, n-octyl or benzyl;or, if appropriate, in E/Z isomer, an E/Z isomer mixture and/or a tautomer thereof; a process for preparing and using these compounds and their tautomers; pesticides whose active compound ... 05/18/06 - 20060105969 - Anthelmintic compositions Combinations of avermectins and milbemycins and their derivatives with bis-aryl compounds and their use in combating parasite, especially helminth, infections. ... 05/18/06 - 20060105968 - Compositions comprising highly purified amphotericin b A method for treating fungal infections in a mammal that comprises administering a therapeutically effective amount of a composition comprising amphotericin B and a pharmaceutically acceptable carrier, wherein the amphotericin B is substantially pure. ... 05/11/06 - 20060100165 - Topical application of ivermectin for the treatment of dermatological conditions/afflictions Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective ... 05/11/06 - 20060100164 - Novel antibacterial agents This invention relates to novel macrolides, to the preparation of novel macrolides, to the use of such novel macrolides for preventing, treating, or ameliorating various conditions, and to the use of such novel macrolides as antibacterial agents. ... 03/30/06 - 20060069048 - Novel bicyclic 9a-azalide derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 03/30/06 - 20060069047 - Antibiotic conjugates This invention features a compound of the following formula (I): wherein T is a transportophore, L is a bond or linker, and C is an antibiotic therapeutic agent, the transportophore is covalently bonded to the antibiotic therapeutic agent via the bond or the linker, and the transportophore is an azithromycin ... 03/23/06 - 20060063724 - Active substance combinations having insecticidal and acaricidal properties The present invention relates to novel insecticidally and acaricidally active compound combinations of N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide of the formula (I) and active compounds identified in the disclosure. ... 03/16/06 - 20060058247 - Methods and compositions for treating cystic fibrosis The present invention provides methods of using improved macrolide compositions in the treatment of cystic fibrosis. The macrolide compounds of Formulas 1-21 described herein may be used alone or in a cotherapeutic regimen with other agents that are active against cystic fibrosis. The present invention also provides compositions and methods ... 03/16/06 - 20060058246 - Macrolide compounds endowed with antiinflammatory activity Macrolide compounds endowed with antiinflammatory activity are described, and more particularly macrolide derivatives lacking cladinose in position 3, with antiinflammatory activity, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing them as active ingredient. ... 03/02/06 - 20060046970 - Topical otic compositions and methods of topical treatment of prevention of otic infections A topical otic composition containing an azalide antibiotic. A topical otic composition containing an azalide antibiotic and an medicament. A topical otic composition containing an azalide antibiotic and a polymer suspending agent. And methods for treating or preventing infections in the ear using azalide antibiotic compositions. ... 02/23/06 - 20060040877 - Novel spinosyn-producing polyketide synthases The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns. ... 02/02/06 - 20060025355 - Compositions comprising amphotericin b, methods, and systems A composition includes particles including at least about 95 wt % of amphotericin B, wherein the particles have a mass median diameter ranging from about 1.1 μm to about 1.9 μm. Another composition also includes particles including at least about 95 wt % of amphotericin B, wherein at least about ... 01/26/06 - 20060019908 - Process for the preparation of azithromycin monohydrate isopropanol clathrate The present invention relates to an improved, cost effective and easy process for the preparation of azithromycin monohydrate isopropanol clathrate. The process provides a one-step method of preparing azithromycin monohydrate isopropanol clathrate directly from 9-deoxo-9a-aza-9a-homoerythromycin A. The process comprises at least partial dissolution and/or suspension of 9-deoxo-9a-aza-9a homoerythromycin A in ... 01/19/06 - 20060014707 - Sixteen-member macrolide antiinfective agents where R1, R2, R3, R4, R5, and R6 are as defined herein, and related compounds are disclosed. ... 01/19/06 - 20060014706 - Therapeutic and/or preventive agent for dyschezia (wherein R1 represents a C1-C6 alkyl group and R2 represents a C1-C6 alkyl group). The above erythromycin derivative of Formula (1) has an improving effect on defecation dysfunction; and this improving effect on defecation dysfunction leads to acceleration of normal defecation, unlike a laxative. Further, the above compound of Formula ... 01/05/06 - 20060003948 - Compositions that include a triterpene and a carrier The present invention provides for compositions that includes a triterpene (e.g., betulin) and a carrier (e.g., lanolin). The compositions are useful for skin care (e.g., as cosmetic formulations), and as therapeutic formulations, e.g., for treating topical fungal infections. ... 12/01/05 - 20050267053 - Use of macrolides in pest control There is now described a method of controlling pests with macrolide compounds; more specifically A) a method of controlling pests in and on transgenic crops of useful plants, such as, for example, in crops of maize, cereals, soya beans, tomatoes, cotton, potatoes, rice and mustard, with a macrolide compound, characterized ... 11/17/05 - 20050256063 - Crystal forms of azithromycin The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections. ... 11/17/05 - 20050256062 - Crystal forms of azithromycin The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections. ... 11/10/05 - 20050250712 - Single dose azithromycin The present invention relates to a method of treating infections in humans by administering a single dose of azithromycin. ... 11/10/05 - 20050250711 - Use of macrolides in pest control There is now described a method of controlling pests with macrolide compounds; more specifically A) a method of controlling pests in and on transgenic crops of useful plants, such as, for example, in crops of maize, cereals, soya beans, tomatoes, cotton, potatoes, rice and mustard, with a macrolide compound, characterized ... 11/03/05 - 20050245469 - Crystal forms of azithromycin The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections. ... 11/03/05 - 20050245468 - Anthelmintic composition The present invention provides an anthelmintic composition including an avermectin or milbemycin, together with triclabendazole, and a predetermined quantity of rheology modifier, such as Laponite or xanthan gum, sufficient to render the anthelmintic composition suitable as an oral drench. ... 10/27/05 - 20050239724 - Skin penetration enhancing components The present invention relates to a topical formulation for the treatment of a dermatological condition which comprises a macrocyclic lactone antibiotic, immunosuppressive macrolide or a biologically active analogue, derivative or pro-drug thereof; characterized in that it further comprises a permeation modulator and the permeation modulator and the macrocyclic lactone or ... 10/27/05 - 20050239723 - Compositions and methods useful for treatment of acne wherein R1, R2, R3 and R4 are selected from a group consisting of a carboxyl group, methyl group, ethyl group, propyl group, isopropyl group, butyl group, isobutyl group, secondary butyl group, tertiary butyl group, pentyl group, isopentyl group, neopentyl group, fluorine, chlorine, bromine, iodine and hydrogen. ... 10/27/05 - 20050239722 - Composition for the treatment of ear infections and method A composition for treating ear infections in animals includes an antifungal agent, an antibiotic agent, a steroidal anti-inflammatory agent, and an acid dissolved to form a liquid. The acid aids in keeping the steroidal anti-inflammatory agent in solution, and enhances the bactericidal effect of the composition. The method of preparing ... 10/20/05 - 20050233986 - Insecticidal mixture containing gamma-cyhalothrin An insecticidal mixture of gamma-cyhalothrin [(S)-α-cyano-3-phenoxybenzyl (Z)-(1R,3R)-3-(2-chloro-3,3,3-tzifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate] and one or more further active ingredients; compositions containing them and their use. ... 10/13/05 - 20050227931 - Use of macrolides in pest control There is now described a method of controlling pests with macrolide compounds; more specifically A) a method of controlling pests in and on transgenic crops of useful plants, such as, for example, in crops of maize, cereals, soya beans, tomatoes, cotton, potatoes, rice and mustard, with a macrolide compound, characterized ... 10/06/05 - 20050222052 - Process for preparing high purity azithromycin A method for preparing high purity azithromycin is described characterised in that the intermediate 9a-deoxo-9a-aza-9a-homoerythromycin A is crystallised and obtained at very high purity, the subsequent methylation reaction effected on said intermediate proceeding with very high specificity and conversion enabling azithromycin of particularly high purity to be obtained. ... 10/06/05 - 20050222051 - Synergistic insecticidal mixtures and at least one further known active compound selected from the group consisting of abamectin, emamectin or emamectin benzoate, methiocarb, β-cyfluthrin and lambda-cyhalothrin, and to the use of these mixtures for protecting plants against attack by pests. ... 09/29/05 - 20050215495 - Macrolide antibiotics The present invention relates to 11,12 γ lactone ketolides of formula (I) wherein R, R1, R2, R3 are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or ... 09/22/05 - 20050209172 - Lyophilized azithromycin formulation The invention provides among other things a stable, sterile pharmaceutical formulation comprising lyophilized azithromycin and ethanol. The invention also provides a method of producing a stable, sterile pharmaceutical product comprising lyophilized azithromycin. The invention also provides a pharmaceutical dosage form comprising the pharmaceutical formulation, as well as a method of ... 09/15/05 - 20050203035 - Polymorphic forms of 6-11 bicyclic ketolide derivatives The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are provided methods of producing the various polymorphic forms in pure form or in combination with one another. ... 09/15/05 - 20050203034 - Multi-action anthelmintic formulations The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus tetrahydropyrimidines. An examples of a tetrahydropyrimidine includes pyrantel. A pharmaceutical formulation is provided for use in the treatment of helminthiasis of mammals, and particularly tapeworm, hookworm, roundworm ... 09/08/05 - 20050197302 - Antiparasitic composition There is provided an improved antiparasitic composition comprising an antiparasitically effective amount of an organic amine salt of closantel optionally a macrocyclic lactone and a non-irritating solvent system consisting essentially of an alcohol and a glycol derivative. Also provided are a method for obtaining increased levels of closantel in the ... 09/01/05 - 20050192234 - Crystal forms of azithromycin The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections. ... 08/25/05 - 20050187169 - 6-11 bicyclic erythromycin derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 08/18/05 - 20050181999 - Synergistically pro-penetrating solutions for ungual/peri-ungual dermatological/cosmetic applications Topically applicable dermatological/cosmetic compositions suited for ungual/peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic ... 08/11/05 - 20050176657 - Anthelmintic oral homogeneous veterinary pastes This invention provides for, inter alia, oral homogeneous veterinary pastes for the treating, controlling and preventing of endo- and ectoparasite infections in warm-blooded animals or birds, such as horses and household pets. This invention further provides for a process of preparing these veterinary pastes and for a method for increasing ... 08/11/05 - 20050176656 - 4-deoxy-4-(s)-amido avermectin derivatives A compound of formula (I); that has the S-configuration at the 4″-position and wherein the bond between carbon atoms 22 and 23 is a single or a double bond; R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2-C12alkenyl; R2 is H, or, for example, unsubstituted or mono- to penta-substituted C1-C12alkyl, C2-C12alkenyl, C2-C12alkynyl or ... 08/11/05 - 20050176655 - Novel macrolide derivatives havaing effect of potentiating antifungal activity wherein R1 is Ac, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is H, when R1 Bzl, R2 and R3 are Bzl, and R4 is ... 08/04/05 - 20050171034 - Compositions and methods for the regulation of homocysteine levels within the body Described herein is a method for reducing levels of the harmful metabolic waste product of S-adenosylmethionine (SAMe), homocysteine, and provide vitamin and other nutritional co-factors that reduce the production of homocysteine and either re-methylate homocysteine back to S-adenosylmethionine, or facilitate its conversion downstream to cystathione. The method of the invention ... 08/04/05 - 20050171033 - 9n-substituted 6-11 bicyclic erythromycin derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 08/04/05 - 20050171032 - Methods for the treatment of cancer The present invention relates to a method for treating a mammalian tumor/cancer using a polyene macrolide antibiotic selected from the group consisting of Filipin, Candicidin, Pimaricin, Nystatin, Etruscomycin and Candidin. In a preferred embodiment, the method further comprises administration of a cholesterol lowering agent. ... 07/28/05 - 20050164959 - Method of treating eye infections with azithromycin The invention features methods and compositions for treating ocular infections. The method comprises topically administering to an eye of an animal in need of such treatment an ocular infection-treating amount of azithromycin. ... 07/28/05 - 20050164958 - O-alkyl macrolide and azalide derivatives and regioselective process for their preparation The present disclsoure relates to new 11-O-alkyl macrolides and azalides and pharmaceutically acceptable salts and solvates thereof, and to pharmaceutical compositions thereof. The disclosure also relates to a process for the preparation of 11-O-alkyl macrolides and azalides by regioselective 11-O-alkylation of macrolides and azalides having a vicinal diol system, using ... 07/21/05 - 20050159370 - 6-11 bicyclic ketolide derivatives which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the ... 07/21/05 - 20050159369 - Method of treatment of otitis externa This invention relates to a method of treating otitis externa using a topical combination medication, including one or more antifungal agent such as, for example fluconazole, voriconazole, itraconazole, clotrimazole, amphotericin B, caspofungin, micafungin, terbinafine, naftifine, butenafine, amorolfine, ravuconazole, posaconazole, flucytosine, econazole, enilaconazole, miconazole, oxiconazole, saperconazole, sulconazole, terconazole, tioconazole, nikkomycin Z, ... 07/21/05 - 20050159368 - Wound treatment composition and process of manufacture A wound treatment composition contains one or more antimicrobial agents that alone or in combination have antibacterial and antifungal properties, a vasoconstriction agent, a steroidal anti-inflammatory, a stimulant, and a carrier. The wound treatment composition may optionally include a demulcent agent and a skin disinfectant agent. A process of manufacturing ... 07/07/05 - 20050148520 - Avermectin derivatives between R1 and the carbon atom at 4′-position represents a single bond, R1 represents —OCH(R1a)(R1b) (wherein R1a represents a lower alkyl or the like and R1b represents a hydrogen atom or the like) or the like, and R2 represents a hydroxyl group or the like. ... 07/07/05 - 20050148519 - Salts of pharmacologically active compounds The present invention relates to compositions containing at least two pharmacologically active ingredients. The compositions comprise a proton-donating pharmacologically active ingredient and a proton-accepting pharmacologically active ingredient in the form of a neutral salt. The salt can be dissolved in a solvent. Also provided are methods of administering pharmacologically active ... 06/30/05 - 20050143325 - Topical invermectin composition A topical gel composition comprising between about 0.005 and 1.0% ivermectin, between about 30 and 40% of a pharmaceutically acceptable alcohol, between about 30 and 40% of a pharmaceutically acceptable glycol, and a pharmaceutically acceptable carrier, useful for treating Pediculosis capitis infestation in a human patient. ... 06/23/05 - 20050137148 - Compositions and methods for treating or preventing diseases of body passageways The present invention provides methods for treating or preventing diseases associated with body passageways, comprising the step of delivering to an external portion of the body passageway a therapeutic agent. Representative examples of therapeutic agents include anti-angiogenic factors, anti-proliferative agents, anti-inflammatory agents, and antibiotics. ... 06/16/05 - 20050130913 - Synergistic insecticidal mixtures and at least one further known active compound from the series abamectin and emamectin and/or emamectin benzoate, and to the use of these mixtures for controlling animal pests. ... 06/09/05 - 20050124561 - Methods and materials for treating and preventing inflammation of mucosal tissue The invention involves methods and materials for treating and preventing non-invasive fungus-induced mucositis. Specifically, the invention involves administrating an antifungal agent such that it contact mucus in an amount, at a frequency, and for a duration effective to prevent, reduce, or eliminate non-invasive fungus-induced rhinosinusitis. This invention also provides methods ... 06/02/05 - 20050119194 - Methods of using and compositions comprising thalidomide for treatment, modification and management of fibromyalgia Methods of treating, preventing, modifying and/or managing fibromyalgia and related conditions are disclosed. Specific embodiments encompass the administration of thalidomide, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent and/or physical or psychological therapy. Pharmaceutical compositions, single unit ... ### FreshPatents.com Support |