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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > O-glycoside > > Oxygen Of The Saccharide Radical Bonded Directly To A Nonsaccharide Hetero Ring Or A Polycyclo Ring System Which Contains A Nonsaccharide Hetero Ring

Oxygen Of The Saccharide Radical Bonded Directly To A Nonsaccharide Hetero Ring Or A Polycyclo Ring System Which Contains A Nonsaccharide Hetero Ring

Oxygen Of The Saccharide Radical Bonded Directly To A Nonsaccharide Hetero Ring Or A Polycyclo Ring System Which Contains A Nonsaccharide Hetero Ring patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

01/04/07 - 20070004652 - Treatment of occlusive thrombosis
The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing a flavanol, an A-type procyanidins, a B-type procyanidin or a derivative thereof, and methods of use thereof, for treatment and/or prevention of occlusive thrombosis and related conditions. ...

01/04/07 - 20070004651 - Active ingredient combinations of one or more isoflavonoids and carnitine and/or one or more acyl-carnitines
Active ingredient combinations of (a) one or more isoflavonoids and (b) carnitine and/or one or more acylcarnitines. ...

01/04/07 - 20070004650 - Endurance improving agent
The present invention is useful as endurance improving agents or antifatigue agents for physical activities in broad sense, such as exercises requiring endurance, labor requiring repeated muscle exercise, and the like. The present invention relates to endurance improving agents, antifatigue agents and AMPK activators, all of which contain catechins as ...

01/04/07 - 20070004649 - Anti-influenza virus compound comprising biflavonoid-sialic acid glycoside
The compounds of the present invention comprise biflavonoid-sialic acid conjugates. Such biflavonoid-sialic acid conjugates show anti-influenza virus activities, not only in in vitro systems using cultured cells, but also in in vivo systems using mice. Thus, they are useful as preventive or therapeutic agents for influenza, and moreover, are useful ...

12/28/06 - 20060293259 - Compositions and methods of use of derivatized flavanols
The invention relates to compositions containing derivatized flavanols such as methylated flavanols, and methods of use thereof for prophylactic or therapeutic treatment of a human or a veterinary animal for example as anti-platelet agents. ...

12/28/06 - 20060293258 - Method and composition to treat skin ulcers
The invention is directed to a method for treating ulcers, including ulcers of the lower leg, by topical plus oral administration of proanthocyanidins to a patient. ...

12/28/06 - 20060293257 - Methods for the treatment of scar tissue
A topical composition and method for the reduction of scar tissue and/or improving the appearance of scar tissue after it has formed. The topical composition includes one or more flavonoids formulated in a pharmaceutically acceptable topical carrier. The method includes the step of topically applying a composition including one or ...

12/28/06 - 20060293256 - Remedy or preventive for kidney disease and method of diagnosing kidney disease
A novel agent for therapy and/or prevention of kidney diseases as well as a diagnostic method (detection method) of kidney diseases is disclosed. The agent for therapy and/or prevention of kidney diseases comprises as an effective ingredient a substance which inhibits casein kinase 2. The diagnostic method of kidney diseases ...

12/21/06 - 20060287257 - Pharmaceutical compositions to treat diseases caused by mycobacterium
The invention teaches the synthesis of pharmaceutical composition and methods of synthesis to treat people and animals infected with a pathogenic mycobacterium. In particular the compositions of this invention are suitable for the treatment of tuberculosis, malaria, and other infections diseases caused by mycobacterium. ...

12/21/06 - 20060287256 - Novel nutraceutical compositions and use thereof
Compositions comprising, as the active ingredients, resveratrol, a derivative, metabolite or analogue thereof, and at least one additional component selected from EGCG, genistein, vitamin E, polyunsaturated fatty acids, gamma-linolenic acid and vitamin K are disclosed. The compositions exert an antiinflammatory effect and may be a food or beverage or a ...

12/14/06 - 20060281694 - Glucose levels
Disclosed are methods and compositions for improving blood glucose levels in a subject in need thereof. ...

12/14/06 - 20060281693 - Renal function improvement
This invention relates to a method of improving renal function comprising administering to a subject in need thereof a composition comprising the inventive compounds. Also disclosed is a method of improving renal function where the subject is at risk of or suffering from renal failure. ...

12/07/06 - 20060276417 - Treatment of inflammation
This invention relates to a method of treating inflammation comprising administering to a subject in need thereof a composition comprising the inventive compounds. Also disclosed is a method of treating inflammation where the subject is suffering from a rheumatic or inflammatory bowel disease. ...

12/07/06 - 20060276416 - Methods and compositions for treating flushing and drug induced weight gain
Provided herein are methods and compositions for treating and/or preventing flushing and/or weight gain. Methods may comprise modulating the activity or level of a sirtuin, such as SIRT1 or Sir2. Exemplary embodiments include methods and compositions for counteracting drug-induced weight gain and/or drug-induced flushing by administering a sirtuin-activating compound. ...

11/30/06 - 20060270615 - Compositions suitable for the treatment of damage caused by ischemia/reper-fusion or oxidative stress
A preparation contains a) at least one substance having xanthine oxidase inhibiting properties; b) at least one substance having superoxide radical scavenging properties; c) at least one substance having peroxyl radical scavenging properties; These preparations are particularly suitable for treating damage caused by ischemia/reperfusion and oxidative stress, preventing multiple organ ...

11/23/06 - 20060264384 - Compositions and methods for treatment for neoplasms
The invention features compositions including two, three, or more agents useful in treating a patient with a neoplasm, methods for treatment of a patient with a neoplasm such as cancer (e.g., brain cancer), kits which include one, two, three, or more agents useful in the treatment of cancer, as well ...

11/09/06 - 20060252708 - Compositions of flavones and long chain fatty acid derivatives isolated from plants and methods related thereto for the control of prostate disorders
Disclosed herein is the extraction, separation, and preparation of plant medicinal extracts to provide compositions containing enriched and isolated flavone derivatives of formula I and long chain fatty acid derivatives of formula II from natural plants, wherein R1, R2, R3, R4, R5, X, A, B and n1 are as defined ...

11/09/06 - 20060252707 - Pharmaceutical composition for the treatment and/or the prevention of atherosclerosis from infectious origin
The present invention is related to a pharmaceutical composition suitable for the treatment and/or the prevention of atherosclerosis from infectious origin, which comprises an adequate pharmaceutical carrier, a corticosteroid and a stilbene-type alexin, preferably further comprising a flavonoid to regenerate the stilbene and/or to increase the effect of the latter. ...

11/09/06 - 20060252706 - Composition for slimming
The present invention relates to a composition for slimming, more particularly, to a slimming composition containing theanine and at least on selected from the group consisting of caffeine, genistein, L-carnitine and catechin. The composition of the present invention contains theanine and each of caffeine, genistein, L-carnitine or mixtures thereof, and ...

11/02/06 - 20060247183 - Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye
The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis(eczema), allergic contact dermatitis, seborrheic dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory ...

10/26/06 - 20060241059 - Treatments for viral infections
The present invention relates to improved methods and compositions for treating viral infections and other diseases and conditions that induce a cytokine storm. More particularly, the present invention relates to novel compositions comprising quercitin, and an anti-convulsant, such as phenytoin, in combination with mulivitamins as an anti-viral composition and methods ...

10/19/06 - 20060234957 - Adiponectin expression promoter
To prevent or alleviate various pathologies caused by lifestyle-related diseases, etc., the present invention provides a substance having an effect of promoting the expression and elevating the expression level of adiponectin, and applications thereof. An adiponectin expression promoting agent containing, as an active ingredient, at least one cyanidin compound selected ...

10/12/06 - 20060229262 - Pharmaceutical composition for treatment of infection with drug resistant bacterium and disinfectant
The present invention provides a pharmaceutical composition or a method for treatment of infections with a drug resistant bacterium including a flavonoid as an active ingredient, and also, a pharmaceutical composition or a method for treatment of infections with a drug resistant bacterium and a disinfectant including a flavonoid which ...

09/21/06 - 20060211635 - Purifications of pomegranate ellagitannins and their uses thereof
Compositions of purified and biologically active ellagitannins are provided by separation from pomegranate husk using a method of extraction and purification using a solid polymeric adsorbent and the uses of the said compounds ...

09/07/06 - 20060199774 - Remedies
The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring enhancement of NGF ...

08/31/06 - 20060194746 - Method and composition to inhibit infections with helicobacter pylori by intake of procyanidins from type b and c
Methods and compositions, including, foods and beverages, for treating, preventing or ameliorating Helicobacter pylori-associated disorders, particularly disorders of the gastrointestinal tract such as peptic ulcers of the stomach are provided by this disclosure. In one preferred aspect, the method comprises administering to a Helicobacter pylori infected subject a therapeutically effective ...

08/10/06 - 20060178318 - Use of aurora kinase inhibitors for reducing the resistance of cancer cells
This invention relates to the use of anti-cancer agents that inhibit mitotic spindle assembly in target cells, including taxanes such as paclitaxel, and in particular to methods and means for predicting and/or reducing the resistance of cancer cells to such agents. Over-expression of aurora kinases, such as Aurora A, mediates ...

07/20/06 - 20060160753 - Micronutrient formulation for cognitive & mood benefits
A food product or dietary supplement is provided comprising (i) preferably at least 5 mg in total, of one or more isoflavones, (ii) preferably at least 0.1 mg, vitamin B6, and optionally (iii) preferably at least 1 mg, vitamin E. The food product or dietary supplement can be used to ...

07/06/06 - 20060148728 - Novel podophyllotoxin compositions
The present invention discloses compositions comprising podophyllotoxins, analogs thereof, or derivatives thereof, and a surfactant. The invention also discloses a podophyllotoxin composition further comprising a targeting moiety. The present invention also discloses a method of delivering a podophyllotoxin, an analog thereof or a derivative thereof, to a cell by administering ...

07/06/06 - 20060148727 - Folate based composition for neurological and cognitive applications
New formulations for the prevention and treatment of neurological diseases and cognitive deficiencies, particularly Alzheimer's Disease comprise folate in combination with compounds chosen to address some or all of the pathways which can result in neurological deficiencies and diseases, namely inflammation, oxidative stress, glycation/dysinsulinemia, platelet function, homocysteine levels and acetylcholinesterase ...

07/06/06 - 20060148726 - Pharmaceutical compositions comprising flavonoids and menthol
The present invention relates to use of certain antiviral fragrances for reduction of viruses, in particular vira causing common cold. In one embodiment, the invention relates to pharmaceutical compositions comprising an antiviral fragrance, preferably menthol. Said compositions preferably also comprise one or more flavonoids. The invention also relates to treatment ...

06/29/06 - 20060142213 - Methods for treating neuropathological states and neurogenic inflammatory states and methods for identifying compounds useful therein
The present invention provides methods for treating neuropathological states and neurogenic inflammatory states in a subject. The present invention also provides methods for identifying compounds that can be used to treat such states. Preferably, the compounds alter the distribution of NMDA glutamate receptor NR1 subunit in cells, and/or alter the ...

06/29/06 - 20060142212 - Nutrient pharmaceutical formulation comprising polyphenols and use in treatment of cancer
A nutrient pharmaceutical formulation composition useful for treating cancer comprising ascorbic acid, L-lysine, L-proline and at least one polyphenol compound selected from the group consisting of epigallocatechin gallate, epicatechin gallate, epigallocatechin, epicatechin, catechin and the use of the composition in treating cancer and other tumors are provided. A nutrient pharmaceutical ...

06/29/06 - 20060142211 - Chromones and chromone derivatives and uses thereof
The present invention relates to chromones, novel chromone derivatives, and pharmaceutical formulations containing the same and methods of use thereof. Uses of the present invention include, but are not limited to, use for the prevention and treatment of septic shock, organ injury and other disorders. The compounds described herein can ...

06/22/06 - 20060135446 - Composition for improving blood fluidity
The present invention provides a composition for improving blood fluidity that comprises proanthocyanidins and an antioxidant (which is a substance other than proanthocyanidins, ascorbic acid and its derivatives) as active components. The composition for improving blood fluidity of the present invention improves blood flow in the body and further improves ...

06/22/06 - 20060135445 - Breast cancer-resistant protein inhibitor
and glycosides, esters, or salts thereof; and an anticancer agent containing the BCRP-inhibitor together with an anticancer agent available as the substrate of BCRP. ...

06/22/06 - 20060135444 - Combination of flavonoid and procyanidin for the reduction of the mammalian appetite
A nutritional composition suitable for reducing appetite, a method for the treatment and/or prevention of overweight and a method for the reduction of a mammalian appetite. The weight reduction and/or appetite reduction is achieved by administration of procyanidin and a flavonoid selected from the group consisting of chrysin, flavone, precursors ...

06/15/06 - 20060128640 - Combination of a taxane and a cyclin-dependent kinase
The invention relates to a pharmaceutical combination comprised of paclitaxel (Taxol®), docetaxel (Taxotere®), or derivatives of them, and a cyclin-dependent kinase inhibitor. It also relates to a method of administration of such a combination, where the taxane is given intermittently and the cyclin-dependent kinase is given repeatedly within the same ...

06/01/06 - 20060116334 - Folate based composition for treatment of the cardiovascular system
New formulations for the prevention and treatment of cardiovascular diseases arthrosclerosis and risk factors thereof including elevated cholesterol and blood pressure levels comprise phytosterols, flavones and folate, alone or in combination, along with additional compounds chosen to address some or all of the pathways which can result in cardiovascular diseases, ...

06/01/06 - 20060116333 - Composition for protecting organ, tissue or cell and utilization thereof
The present invention provides a composition for efficiently protecting and preserving organs, tissues or cells. In particular, the present invention provides a protective composition which can be used during operations. Specifically, the present invention provides a composition for protecting and preserving organs, tissues or cells, comprising a polyphenol. A method ...

05/25/06 - 20060111308 - Methods and compositions for therapeutic treatment
Methods and compositions are described for the modulation of central nervous system and/or fetal effects of substances. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of drugs and other compounds out of a physiological compartment and into an external environment. In particular, ...

05/25/06 - 20060111307 - Methods and compositions for treating pain
Methods and compositions are described for the modulation of central nervous system and/or fetal effects of substances. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of drugs and other compounds out of a physiological compartment and into an external environment. In particular, ...

05/18/06 - 20060105967 - Flavone derivatives as tnfalpha inhibitors or antagonists
in which R1, R2, R3, R4 and R5 independently represent hydrogen, hydroxy or an ester group; R6 represents hydrogen, hydroxy, an ester group or an O-glycoside group such as O-rhamnose, O-glucoside, O-retinoside or O-xyloside; and represents a single bond or a double bond; or the pharmaceutically acceptable salts thereof ...

04/20/06 - 20060084615 - Puerarin derivatives and their medical uses
The present invention provides acetylated derivatives of the compound puerarin that have enhanced bioavailability and are particularly suitable for oral administration. The present invention also teaches the use of medicaments containing acetylated derivatives of puerarin that are suitable for the treatment of myocardial ischemia and for modulating blood lipid levels, ...

04/13/06 - 20060079467 - Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions
The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-Ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic ...

03/30/06 - 20060069046 - Process for the production of (-)-epigallocatechin gallate
A process is provided for making (−)-epigallocatechin gallate (EGCG) by subjecting a green tea extract to chromatography on a macroporous polar resin, eluting EGCG from the resin with a polar elution solvent, optionally concentrating the eluate, optionally regenerating the resin by desorbing the remaining catechins, and optionally concentrating the desorbed ...

03/30/06 - 20060069045 - Methods for treating familial dysautonomia
The present invention provides methods for modulating mRNA splicing in a normal or diseased cell or individual, e.g., elevating wild-type IKBKAP transcripts and the level of functional IKAP protein in an individual suffering from Familial Dysautonomia, by providing catechins, such as EGCG, to the cell or individual. The present invention ...

03/16/06 - 20060058245 - Methods for treatment of thiol-containing compound deficient conditions
Methods for therapy of cystic fibrosis and other conditions are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a transporter system (i.e. ABC transporters such as MDR-1 or MRP-2) in cells. Other embodiments include the use of agents to modulate transport of thiol-containing ...

02/23/06 - 20060040876 - Modulation of peroxisome proliferator-activated receptors
A method of treating a peroxisome proliferators-activated receptors related disease by administering to a subject in need thereof an effective amount of a modulator of 15-keto prostaglandin-Δ13-reductase. Also disclosed are methods of identifying a compound for inhibiting activity of the reductase and of lowering blood glucose levels by administering to ...

02/23/06 - 20060040875 - Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2b (ugt2b)
A UGT2B inhibitor capable of increasing the bio-availability of a drug, being a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, ...

02/16/06 - 20060035847 - Glucopyranosyloxyprazole derivatives and use thereof in medicines
(wherein P represents a hydrogen atom or a group forming a prodrug), while the other represents a lower alkyl group or a halo(lower alkyl) group; R2 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a halo (lower alkyl) group or a halogen ...

02/16/06 - 20060035846 - Preventing/correcting functional disorders of the pilosebaceous unit of mammals
Orally administratable cosmetic compositions, notably formulated as food supplements, useful for the prevention and/or treatment of functional disorders of the pilosebaceous structural unit of mammals, in particular by combating the cutaneous activation of the androgens over time, and especially for the treatment of oily and/or hyper-seborrheic skin and/or scalp, thin ...

02/02/06 - 20060025354 - Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia
A method for the treatment of obesity, diabetes, high cholesterol and related diseases including hyperglycemia, lipid disorders, hyperglyceridemia, dyslipidemia and atherosclerosis in mammals using anthocyanins, anthocyanidins, ursolic acid and/or betulinic acid is described. Compositions adapted for these treatments are also described. ...

02/02/06 - 20060025353 - Insulin secretion by anthocyanins and anthocyanidins
A method for stimulating insulin secretion by anthocyanidins and anthocyanins is described. The secretion can be in vivo in mammals, including humans, or in vitro. ...

01/19/06 - 20060014705 - Compositions and methods for selectively activating human sirtuins
Methods for identifying selective activators of SIRT5 and/or SIRT1 and methods for using these selective activators in the modulation of SIRT5 and/or SIRT1 are provided. ...

12/29/05 - 20050288237 - Novel derivative of flavone c-glycoside and composition containing the same
The present invention relates to novel flavone C-glycoside derivatives or salts thereof, especially those showing an anti-allergic effect, and compositions containing them. Recently, cases of allergic diseases, especially pollenosis and atopic dermatitis have increased to such a degree that they have become a social problem. Flavones and their glycosides have ...

12/15/05 - 20050277600 - Compositions and methods of use of dimer digallates
The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing dimer digallates, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent NO-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease, diabetes, cognitive ...

12/01/05 - 20050267052 - Epicatechin for hypertension treatment
Disclosed and claimed are flavanols, e.g. epicatechin, compositions such as pharmaceutical compositions containing an effective amount of flavanols, e.g. epicatechin, and methods of treatment or prevention of hypertension using the same. ...

11/17/05 - 20050256061 - Use of isoflavones for preparing topical compositions for promoting slimming, and related cosmetic treatment method
The invention concerns the use of isoflavones for ping topical compositions for promoting slimming, and in particular for fighting against localized excess weight; the related cosmetic treatment method and a composition comprising additionally to isoflavones an extract of Sophora Japonica flowers. ...

11/10/05 - 20050250710 - Antiaging composition
The present invention provides an antiaging composition capable of efficiently retarding skin-aging, particularly, alleviating skin pigmentation. The present invention also provides a method for potentiating the antiaging action of ascorbic acids. The invention provides an antiaging composition containing at least one member selected from the group consisting of ascorbic acid, ...

11/03/05 - 20050245467 - Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract
The present invention relates to methods of treating conditions and/or symptoms related to common cold of the upper and/or lower respiratory tract and/or eyes. In particular the invention relates to the methods of treating conditions and/or symptoms related to common cold comprising administration of a flavonoid or administration of a ...

11/03/05 - 20050245466 - Use of topoisomerase inhibitors and heat shock protein 90 inhibitors for use in chemotherapy
The present invention relates to the use of a first agent that attenuates topoisomerase II (Topo II) activity and a second agent that inhibits Heat Shock Protein 90 (HSP90) for use in chemotherapy. The agents are particularly useful in the treatment of cancer and destruction of micro-organisms. The invention also ...

10/27/05 - 20050239721 - Methods for the treatment of peripheral neural and vascular ailments
Compositions and methods for the treatment of peripheral neural and vascular ailments are disclosed. The method comprises administering a flavonoid compound with antioxidant properties, optionally formulated in a acceptable carrier. This compound or combination of compounds provides significant, effective relief of the symptoms of peripheral neural or vascular ailments. In ...

10/27/05 - 20050239720 - Combination of an agent that attenuates topoisomerase 1 activity and an agent that inhibits heat shock protein 90 for use in chemotherapy
The present invention relates to the use of a first agent that attenuates Topoisomerase I (Topo I) activity and a second agent that inhibits Heat Shock Protein 90 (HSP90) for use in chemotherapy. The agents are particularly useful in the treatment of cancer and destruction of micro-organisms. The invention also ...

10/20/05 - 20050233985 - Rsk inhibitors and therapeutic uses thereof
The present invention is directed to novel compounds and compositions that have Rsk specific inhibitory activity. In addition, inhibition of Rsk by the present compounds has been discovered to halt the proliferation of cancer cell lines while having little effect on the proliferation rate of normal cells. Therefore, the present ...

10/13/05 - 20050227930 - Cholesterol lowering combination
Compositions and methods for the treatment for the prevention and treatment of hypercholesterolemia and atherosclerosis are described. Individuals at a high risk of developing or having hypercholesterolemia and atherosclerosis may be treated with an effective dose of a composition comprising at least one citrus flavonoid, at least one tocotrienol, and ...

10/13/05 - 20050227929 - Combination therapy comprising a cox-2 inhibitor and an antineoplastic agent
A method for treating or preventing neoplasia or a neoplasia-related disorder in a subject is provided, the method comprising administering to the subject an effective amount of a combination comprising a Cox-2 inhibitor and an antineoplastic agent. ...

10/06/05 - 20050222050 - Compositions and methods for reducing or preventing obesity
Compositions useful for weight management in an animal are disclosed. The compositions comprise one or more isoflavones or isoflavone metabolites, and in some embodiments include conjugated linoleic acid, and/or L-carnitine. Also disclosed are methods useful for weight management in an animal utilizing compositions comprising one or more isoflavones, conjugated linoleic ...

09/29/05 - 20050215494 - Baicalin and its derivatives as a treatment for sars coronavirus infection or other related infections
The present invention relates to a pharmaceutical composition useful for the treatment of diseases associated with viruses of the order Nidovirales of the family Coronaviradae, such as Severe Acute Respiratory Syndrome (SARS) viruses in humans and other animals. In particular, this invention relates to a naturally occurring compound, namely, baicalin, ...

09/29/05 - 20050215493 - Calcium-containing tissue strengthening agents and use thereof
The present invention has an object to provide an agent for strengthening calcium-containing tissues, which can be safely applied; and its use: The present invention solves the object by providing an agent for strengthening calcium-containing tissues, which comprises one or more flavones, flavonols, flavanones, flavanonols, anthocyanidins, flavanols, chalcones, and aurones. ...

09/29/05 - 20050215492 - Ameliorant for chemical treament of cancer
According to this invention, a novel ameliorating agent for cancer chemotherapy is provided which acts safely and effectively in a small dosage to enhance the carcinostatic action of an anti-cancer agent in cancer chemotherapy and repressing side effects by cancer chemotherapy as well. ...

09/22/05 - 20050209171 - Treatment of periodontal disease
wherein n is an integer from 2 to 18, such that there is at least one terminal monomeric unit A, and one or a plurality of additional monomeric units; R is 3-(α)-OH, 3-(β)-OH, 3-(α)-O-sugar, or 3-(β)-O-sugar; bonding between adjacent monomers takes place at positions 4, 6 or 8; a bond ...

09/22/05 - 20050209170 - Breast health preparations
Novel preparations of phytochemical ingredients that are serviceable as health supplements for the body, particularly tissues susceptible to cancer, including, e.g. prostate tissue and breast tissue and, including, e.g., female breast tissue; for example, all possible combinations and permutations of member from each of the following 5 groups: 1) plant ...

09/15/05 - 20050203033 - Identification and characterization of an anthocyanin mutant (ant1) in tomato
Flavonoids are obtained from plants that overexpress an ANT1 gene compared to wild-type plants. The plant may be a transgenic plant that contains a transformation vector that causes the overexpression of ANT1. Alternatively, the plant can be selectively bred to have an allele of or mutation in an endogenous ANT1 ...

08/11/05 - 20050176654 - Composition for regulating bone metabolism
The present invention provides a composition for regulating bone metabolism that comprises proanthocyanidins. It is preferable that the proanthocyanidins in this composition for regulating bone metabolism are contained in an extract derived from a natural product, and the extract comprises at least 20 wt % of oligomeric proanthocyanidins having a ...

08/04/05 - 20050171031 - Method and composition for the treatment of cancer
We have discovered that the administration of a G1 and/or S phase drug such as β-lapachone in combination with a G2/M drug such as a taxane derivative such as paclitaxel resulted in a unexpected greater than additive (i.e., synergistic) reduction in the number of tumors (and tumor volume) as compared ...

08/04/05 - 20050171030 - Relieving symptoms of erectile dysfunction and attaining sexual wellness and health of the sexual vascular system with proanthocyanidins
Sexual wellness or sexual fitness is enhanced over time by administrating on a daily basis a source of proanthocyanidins and a source of arginine. Both sources may be blended into a composition or taken separately from a kit. The source of arginine may be a salt or peptide of L-arginine ...

08/04/05 - 20050171029 - Methods and compositions for treating cancer
This invention relates to compositions, and methods of use thereof, containing polyphenols such as procyanidins and derivatives thereof, for treating certain tumors, and more generally to inducing dephosphorylation of a hyperphosphorylated cell cycle regulatory protein in a tumor cell in which hyperphosphorylation of said protein contributed to cell transformation. ...

07/28/05 - 20050164957 - 7-hydroxy chromones as potent antioxidants
The present invention describes the identification and purification of 7-hydroxychromes that exhibit potent antioxidant activity. In one embodiment the present invention includes a method for providing an antioxidant to a host in need thereof, comprising administering an effective amount of a 7-hydroxychrome or a mixture of 7-hydroxychromones. The present invention ...

07/28/05 - 20050164956 - Compositions and methods of use of a-type procyanidins
The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing A-type procyanidins, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent NO-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease and/or vascular ...

07/07/05 - 20050148518 - Anti-bacterial compositions
Anti-bacterial composition comprising an admixture of an organic acid (excluding acetate, propionate and butyrate) together with a coumarin or coumarin glycoside. Preferred organic acids include lactate, citrate and benzoate, especially L-lactate. Preferred coumarins are esculetin, scopoletin, imbelliferone and Coumarin (1,2-benzopyrone). The composition, which is effective against E. coli 0157, Salmonella, ...

06/30/05 - 20050143324 - Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye
The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis(eczema), allergic contact dermatitis, seborrheic dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory ...

06/30/05 - 20050143323 - Isoflavone therapy for treating urinary incontinence
A method for preventing or inhibiting urge or stress urinary incontinence while reducing or eliminating undesirable side effects associated with conventional treatments involves administering to an human in need of treatment an effective amount of an isoflavone. ...

06/23/05 - 20050137147 - Agents for treatment of diabetic retinopathy and drusen formation in macular degeneration
Agents that stimulate nuclear translocation of Nrf2 protein and the subsequent increases in gene products that detoxify and eliminate cytotoxic metabolites are provided in a method for treating diabetic retinopathy or drusen formation in age-related macular degeneration. The structurally diverse agents that act on the Nrf2/ARE pathway induce the expression ...

06/23/05 - 20050137146 - Agents for treatment of glaucomatous retinopathy and optic neuropathy
Agents that stimulate nuclear translocation of Nrf2 protein and the subsequent increases in gene products that detoxify and eliminate cytotoxic metabolites are provided in a method for treating glaucomatous retinopathy or optic neuropathy. The structurally diverse agents that act on the Nrf2/ARE pathway induce the expression of enzymes and proteins ...

06/16/05 - 20050130912 - Compositions for the improvement of obesity
The present invention relates to a composition containing genistein that accelerates the expression of the Carnitine Palmitoyl Transferase-1 (CPT-1) for improving or treating obesity. More particularly, the composition of the present invention comprises genistein that accelerates the expression of the CPT-1, an important enzyme for the lipolysis of fatty acid, ...



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