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Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) > O-glycoside O-glycosideO-glycoside patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.02/01/07 - 20070027093 - Anorectic The present invention relates to an anorectic containing a compound having a DGAT inhibitory activity (DGAT1 inhibitory activity) or a prodrug thereof or a pharmaceutically acceptable salt thereof as an active ingredient. The present invention provides an anti-obesity drug which is an anorectic that does not directly act on the ... 01/04/07 - 20070004648 - Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture where the groups groups R1, R2, R3a, R3b, R4, R5, R6, X and R7a, R7b, R7c are defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to the invention are suitable for the treatment of metabolic disorders. ... 01/04/07 - 20070004647 - Proteasome inhibitors and uses thereof The invention relates to methods and compositions for inhibiting proteasome activity using cinnamate compounds. These cinnamate compounds can be formulated for topical or systemic use for skin disorders such as psoriasis. ... 12/28/06 - 20060293254 - Podophyllotoxin The invention relates to podophyllotoxins, uses thereof and methods of their production. ... 12/21/06 - 20060287255 - C-linked glucuronide of n-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals, including humans. ... 12/14/06 - 20060281692 - Use of derivatives of succinate esters for the treatment of dementia The use of extract form Wangla (coeloglossum viride (L) Hartm. Var. Bracteatum (Willd.) Richter), succinate derivative esters, and a derivative and pharmaceutical acceptable salts thereof, for the manufacture of a pharmaceutical preparation for the treatment of dementia, particularly for the treatment of Alzheimer' disease and Vascular dementia. Through Animal experiment, ... 11/30/06 - 20060270614 - Use of chalcones for the treatment of viral disorders The present invention relates to chalcone derivatives and compositions containing such derivatives useful in the treatment of viral disorders, including but not limited to the treatment of viral lesions resulting from viruses such as Herpes Simplex virus. ... 11/23/06 - 20060264383 - Morning glory-derived anticancer agents, and novel ipomoeassin compounds Ipomoeassin compounds derived from morning glory plant material (especially Ipomoea sp. from Suriname) are useful as anti-cancer agents. The novel compounds also are useful for treating neurodegenerative disorders (such as Alzheimer's disease) in human patients. ... 10/12/06 - 20060229261 - Acarbose methods and formulations for treating chronic constipation The present invention is directed to a method for treating chronic constipation in a subject in need of such treatment comprising administering to the subject a dosage formulation comprising a therapeutically effective amount of acarbose, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable ingredient to control ... 10/05/06 - 20060223765 - Method for inhibiting and/or treating vaginal infection A method for inhibiting and/or treating infection in a vagina is provided. The method comprises exposing one or more microbes to a treatment composition. The microbes are selected from the group consisting of Gardnerella, Candida, and Trichomonas, and the treatment composition comprises an effective amount of a saccharide-based nonionic surfactant. ... 08/31/06 - 20060194745 - Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids, ... 08/31/06 - 20060194744 - Illudin analogs useful as antitumor agents R8 is optionally substituted (C1-C4)alkyl; and the bonds represented by --- are individually present or absent. The invention further provides dimers comprising analogs of formula (I). ... 08/24/06 - 20060189549 - Chalcone derivatives and their use to treat diseases or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the application. ... 07/13/06 - 20060154877 - Hemiterpene glycosides with anti-platelet aggregation activities from ilex pubescens Two hitherto unreported novel hemiterpene glycosides were isolated in substantially pure form from the root of Ilex pubescens. The chemical structures and some properties of these hemiterpenes have been elucidated. These hemiterpene glycosides possess anti-platelet aggregation activity more potent than those of salvianolic acid B and aspirin and may be ... 07/13/06 - 20060154876 - Serum cholesterol lowering agent or preventive or therapeutic agent for atherosclerosis A serum cholesterol lowing agent or a preventive or therapeutile agent for atherosclerosis, which each comprises a combination of a compound represented by the following general formula (I) or pharmaceutical acceptable salts thereof with a cholesterol biosynthesis inhibitor and/or a fibrate type cholesterol lowing agent. (I) (b) (a) [In the ... 07/06/06 - 20060148724 - Genipin derivatives and uses thereof Genipin derivatives and pharmaceutical compositions thereof that inhibit the activity of uncoupling protein-2 (UCP2) and are useful in treating deficient first-phase insulin secretion, non-insulin dependent diabetes mellitus, and ischemia in a mammal are disclosed. ... 07/06/06 - 20060148723 - Novel glycolipid and medicine for autoimmune disease containing the same as active ingredient wherein R1 is an aldopyranose group, R2 is a hydrogen atom or a hydroxyl group, R3 is —CH2—, —CH(OH)—CH2— or —CH═CH—, R4 is a hydrogen atom or CH3, x is 0-35, y and z represent integers satisfying y+z=0-3. ... 06/29/06 - 20060142210 - Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture Glucopyranosyl-substituted benzene derivatives defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to the invention are suitable for the treatment of metabolic disorders. ... 06/01/06 - 20060116332 - Methods for inhibition of nkt cells Molecules that interact with the NKT cell antigen receptor and its counterpart antigen presenting molecule, but which inhibit the NKT cell immune function, are administered to a patient. Conditions of particular interest include the treatment of systemic lupus erythematosus (SLE), cancer, atherosclerosis, and allergic disease. In some embodiment of the ... 06/01/06 - 20060116331 - Glycosylceramide analogues Glycosylceramide analogues are disclosed in which the ceramide moiety and optionally the carbohydrate moiety are modified or replaced. These analogues are useful as immunomodulators, antitumor agents, and as other pharmaceutical agents. ... 05/11/06 - 20060100163 - Pharmaceutically active oligosaccharide conjugates The present invention relates to pharmaceutically active oligosaccharide conjugates having the formula: (X—Ym)n—S, wherein component X is a pharmaceutically active compound, Y is a bifunctional linker, and S is an oligosaccharide consisting of 1 to 20 saccharide units, n is equal or less than the number of the saccharide units ... 04/20/06 - 20060084614 - Novel factor viia inhibiting compounds These compounds are very effective factor VIIa inhibitors and are therefore of interest in the treatment and/or prevention of thromboses, stroke, heart attack, inflammation, arteriosclerosis and tumour conditions. ... 04/13/06 - 20060079466 - Rapamycin carbohydrate derivatives This invention provides modified rapamycins that have specific monosaccharide(s), oligosaccharide(s), pseudosugar(s) or derivatives thereof attached through a linker to create rapamycin carbohydrate derivatives having enhanced pharmacokinetic and/or pharmacodynamic profiles. For example, administration of the rapamycin carbohydrate derivative results in altered pharmacokinetic profiles and reduced toxicities. Thus, the present invention provides ... 04/13/06 - 20060079465 - 6r-(3,6-dideoxy-l-arabino-hexopyranosyloxy) heptanoic acid, preparation process for the same and dauer effect thereof The present invention relates to a determination of a stereochemistry, a synthesis and dauer effect of 6R-(3,6-dideoxy-L-arabino-hexopyranosyloxy)heptanoic acid as a pheromone isolated from the Caenorhabditis elegance related to suppress of aging and stress. It becomes possible to develop medical substances using the pheromone relating to aging, stress, metabolism, signal transfer ... 03/30/06 - 20060069042 - Cytochrome p450 2c9 inhibitors This invention is to provide multiple specific inhibitors of cytochrome P450 isozyme CYP2C9. These inhibitors can be derived from any combinations with the following compounds including: Tamarixetin, Formononetin, isoliquritigenin, Phloretin, luteolin, Quercitrin, quercetin, myricetin, Wongonin, Puerarin, Genistein, Nordihydroguaiaretic acid, Narigenin, Capillarisin, Chrysin, Fisefin, eriodictyol, 6-Gingerol, Isorhamneti, isoquercitrin, Morin, (+)-Taxifolin, isovitexin, ... 03/16/06 - 20060058244 - New pyrazole derivatives and diabetic medicine containing them The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine. ... 03/09/06 - 20060052318 - Tyrosinase activity cntrolling agent, process for producing the same and external preparations containing the same Disclosed is a tyrosinase activity controlling agent comprising, as an active ingredient, a compound that has tyrosinase inhibiting or promoting activity, an external preparation comprising the controlling agent, and a process for producing the compound. ... 03/02/06 - 20060046969 - Antibacterial compositions for drug administration An antibacterial composition having at least one alkyl glycoside, at least one saccharide, and at least one therapeutic agent, wherein the alkyl glycoside has an alkyl chain length from about 12 to about 14 carbon atoms and wherein the saccharide has antibacterial activity, thereby providing for a composition having antibacterial ... 02/16/06 - 20060035844 - Preventive or remedy for diseases caused by hyperglycemia The present invention provides pharmaceutical compositions comprising as an active ingredient a selective SGLT1 inhibitor (e.g., an SGLT1 inhibitor substantially showing no GLUT2 and/or GLUT5 inhibitory effect), which have a wider range of inhibitory effect on carbohydrate absorption and a hypoglycemic effect caused by fructose ingestion at regular diets and ... 01/19/06 - 20060014703 - Antimicrobial quaternary surfactants based upon alkyl polyglycoside The invention relates to a series of polyglycoside derivatives that contain water-soluble cationic groups introduced into the molecule by reaction with the hydroxyl groups present in the starting polyglycoside molecule, with an chloro hydroxy propyl containing cationic material. The materials are multifunctional, providing not only wetting, and conditioning, but also ... 01/12/06 - 20060009400 - D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture wherein the groups R1 to R5, X, Z and R7a, R7b, R7c are defined as in claim 1, have an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The present invention also relates to pharmaceutical compositions for the treatment of metabolic disorders. ... 12/15/05 - 20050277599 - Pentose derivatives as anti-hyperglycemic drugs The present invention relates to pentose and pentose derivatives that are effective at increasing glucose transport in a non-insulin dependent manner, and to uses thereof for a) treating and/or preventing hyperglycemia; b) treating and/or preventing the complications of hyperglycemia; c) treating diabetes; d) increasing the rate of cellular glucose transport; ... 12/08/05 - 20050272671 - Compositions comprising hepoxilin analogs and their use in the treatment of cancer wherein X and R3 are as defined herein. The methods are directed to treatment of a cancer and for promotion of a apoptosis in a cancer cell. ... 12/01/05 - 20050267049 - Anti-hypercholesterolemic compounds and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events. ... 12/01/05 - 20050267048 - Bicyclic carbohydrate compounds useful in the treatment of infections caused by herpesviridae wherein R1 is either -Bn or -Ph; R2 and R3 are either -alkyl, -aryl, -allyl, or —H; R4 and R5 form a ring and are either —CH(Ph)- or —CH(aryl)- and X is either O, N or S. ... 11/24/05 - 20050261208 - Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anti-ige antibody for treatment of asthma or chronic obstructive pulmonary disease A pharmaceutical or veterinary composition, comprises a first active agent selected from a dehydroepiandrosterone and/or dehydroepiandrosterone-sulfate, or a salt thereof, and a second active agent comprising an anti-IgE antibody for the treatment of asthma, chronic obstructive pulmonary disease, or other respiratory diseases. The composition is provided in various formulations and ... 11/17/05 - 20050256060 - Mono-and disaccharide derivatives The present invention relates to a novel family of monosaccharide derivatives and disaccharide derivatives and to a method of preparation thereof. A mono- and disaccharide derivatives according to the invention comprises at least one fatty acid ester and may further comprise one or more anionic groups and are useful for ... 11/03/05 - 20050245464 - Use of lipid conjugates in the treatment of diseases This invention provides a method of treating a subject suffering from a dermatologic condition, including, inter alia, psoriasis, contact dermatitis, and seboreic dermatitis, the method includes the step of administering to a subject a compound comprising a lipid or phospholipid moiety bound to a physiologically acceptable monomer, dimer, oligomer, or ... 10/20/05 - 20050233983 - Treatment of rumen acidosis with alpha-amylase inhibitors or veterinarily acceptable salt, solvate (including hydrate) or prodrug thereof; and processes to make an effective inhibitor of a bacterial α-amylase and/or α-glucosidase useful for the treatment of acidosis in a ruminant. ... 09/29/05 - 20050215491 - Compounds and their uses Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or an IPG antagonist thereof. In particular, the compounds are based on the 1,6 ... 09/29/05 - 20050215490 - Polyene polyketides and methods of treating bacterial infections This invention related to methods of inhibiting the growth of bacterial cells and methods of treating bacterial infections in mammals using a novel polyene polyketide. ... 09/29/05 - 20050215489 - Methods of treating diabetes using pde 11a inhibitors Methods of the invention relate to treatment of diabetes, particularly type 2 diabetes, and related disorders by administration of a PDE11A inhibitor. Such PDE11A inhibitors may be administered in conjunction with alpha-glucosidase inhibitors, insulin sensitizers, insulin secretagogues, hepatic glucose output lowering compounds, beta3 agonist or insulin. Such PDE11A inhibitors may ... 08/25/05 - 20050187168 - Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture R1 to R6 and R7a, R7b, R7c are defined as in claim 1, the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly an inhibitory effect on the sodium-dependent glucose cotransporter SGLT2, ... 08/25/05 - 20050187167 - Polyene polyketides, processes for their production and their use as a pharmaceutical This invention relates to a new class of polyene polyketides, their pharmaceutically acceptable salts and derivatives, and to methods for obtaining the compounds. One method of obtaining these compounds is by cultivation of novel strains of Streptomyces aizunensis; another method involves expression of biosynthetic pathway genes in transformed host cells. ... 08/11/05 - 20050176653 - Polyene polyketides and methods of production Novel polyene polyketides, their pharmaceutically acceptable salts, prodrugs and derivatives have been found to have antibiotic activity. One method for obtaining the compounds is by cultivation of Amycolatopsis orientalis ATCC™ 43491 or a mutant or variant such as the strain IDAC-220604-1. Another method for obtaining the compounds is post-biosynthesis chemical ... 08/11/05 - 20050176652 - Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation with the proviso that when Z is —NHR13 and Y is O, at least one of R1, R2, R3, R4, and R5 is hydrogen, or at least one of R6 and R7 is OH, or a pharmaceutically acceptable salt thereof. ... 08/04/05 - 20050171028 - Thioketals and thioethers for inhibiting the expression of vcam-1 Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders, and cancer. The compounds also can be used to treat hyperlipidemia and/or hypercholesterolemia. ... 08/04/05 - 20050171027 - Compositions for treating or preventing obesity and insulin resistance disorders Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or ... 07/28/05 - 20050164955 - Antifungal properties of various forms of sophorolipids The preparation and use of 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Lactonic and Open ring 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Methyl 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Ethyl 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Hexyl 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Ethyl 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6″-acetate and Ethyl 17-L-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6′,6″-diacetate sophorolipids as antifungal agents. ... 07/21/05 - 20050159365 - Hepatits c virus inhibitor comprising alpha-glycosylceramide as the active ingredient This invention provides a growth inhibitor of human hepatitis C virus comprising, as an active ingredient, α-glycosylceramide used for patients infected with the aforementioned viruses. This inhibitor of hepatitis C virus comprises, as an active ingredient, a compound represented by formula (I) or a salt or solvate thereof. ... 06/23/05 - 20050137145 - Metabolites of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol and their use in the treatment of urinary incontinence 1-phenyl-3-dimethylamino-propane compounds for producing a drug for treating urinary urgency or urinary incontinence and corresponding drugs and methods of treating or alleviating urinary urgency or urinary incontinence. ... 06/02/05 - 20050119193 - Novel solid preparation containing block copolymer and anthracycline anticancer agent and process for producing the same There has been required a clinically applicable solid preparation for injection which contains a block copolymer composed of a hydrophilic polymer structure moiety and a hydrophobic polyamino acid structure moiety and an anthracycline anticancer agent. It is intended to provide a clinically applicable solid preparation for injection which contains a ... 06/02/05 - 20050119192 - Crystals of glucopyranosyloxybenzyl benzene derivative The present invention provides crystals of 2-(4-methoxybenzyl)phenyl 6-O-ethoxycarbonyl-β-D-glucopyranoside, pharmaceutical compositions containing the same and their uses, which exhibit excellent SGLT2 inhibitory activities, and are useful for treating or preventing diseases associated with hyperglycemia. ... ### FreshPatents.com Support - Terms & Conditions |