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Chemistry: Analytical And Immunological Testing > Involving An Insoluble Carrier For Immobilizing Immunochemicals

Involving An Insoluble Carrier For Immobilizing Immunochemicals

Involving An Insoluble Carrier For Immobilizing Immunochemicals patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

12/06/12 - 20120309111 - Biosample plate with data storage and wireless communication means
Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing information related to the biosample, biosample plate and biosample analysis data, and a wireless communication interface for transferring information to and from the biosample plate. The biosample plate may be used with an analyzing...

09/20/12 - 20120238039 - Novel immobilizing fusion protein for effective and oriented immobilization of antibody on surfaces
The present invention relates to a novel fusion protein comprising Staphylococcal protein A and mussel adhesive protein, a biochip comprising a solid substrate to which the fusion protein is attached, and a method for detecting a target antigen in a biological sample using the biochip. Furthermore, the present invention relates...

09/06/12 - 20120225497 - Zwitterion-containing acridinium compounds
Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to solid phases and provide increased assay sensitivity....

08/16/12 - 20120208299 - Reduced step dual path immunoassay device and method
Test cells have a first sorbent strip with a sample receiving location and defining a first migration path, a distinct second sorbent strip which receives buffer solution and at least partially defines a second migration path distinct from and elongated relative to the first migration path, conjugate supported by the...

05/24/12 - 20120129272 - Lateral flow assay systems and methods
In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of...

04/19/12 - 20120094397 - Detection method and detection system
In a detection method for detecting the quantity of a target material, a labeled binding material in the amount corresponding to the quantity of the target material contained in a liquid specimen is bonded to the top of a sensor portion; and a signal based on light emitted from a...

03/01/12 - 20120052597 - Recognizable carrier for optical measurement methods
The invention relates to a recognizable carrier for determining physical, chemical or biochemical interactions by means of optical measurement methods. The carrier comprises a surface that defines a substrate surface and that has a base layer coated with reactive elements, which are bonded to receptor molecules, wherein the base layer...

01/19/12 - 20120015451 - Fluid sensor preventing generation of air bubbles
Provided herein is a fluid sensor, which includes a closed reaction unit in which reaction of a fluid sample takes place. The reaction unit is tapered on a side through which the fluid is injected so as to prevent generation of air bubbles during the injection of the fluid. Thus,...

01/05/12 - - Chromatographic assay system
The present application discloses an analyte detection apparatus having at least one reservoir area and a wicking membrane, wherein a labeled specific binding partner is impregnated on the reservoir area; and a region on the wicking membrane where at least one chemical component is immobilized....

10/27/11 - 20110263048 - Insoluble carrier for use in anti-phospholipid antibody measurement reagent, anti-phospholipid antibody measurement reagent, and method for measuring anti-phospholipid antibody
The present invention has an object to provide an insoluble carrier for an antiphospholipid antibody detection reagent having a high reactivity. The present invention also has an object to provide an antiphospholipid antibody detection reagent, and a method of detecting an antiphospholipid antibody. The present invention directs to an insoluble...

10/13/11 - 20110250705 - Nanopore capture system
A nanopore capture system may include a material configured to pass through a nanopore device in a controlled manner based upon its interaction with the nanopore device. The system may also include a capture mechanism connected to one end of the material. The capture mechanism may be configured to catch...

10/06/11 - 20110244596 - Pulsed magnetic actuation for sensitive assays
A method for controlling the movement of magnetic or magnetizable objects (10) in a biosensor cartridge. The method comprises the step of providing a biosensor cartridge with a laterally extending sensor surface (A) and at least a magnetic field generating means (20, 30, 30′) for generating a magnetic field with...

10/06/11 - 20110244597 - Immunochromatographic medium and immunochromatographic method
Disclosed are an immunochromatographic medium and an immunochromatographic method in which, even when plural items exceeding four items are detected which are the number of colors that can be detected by colored latex particles, the plural items can be detected and quantified simultaneously. The immunochromatographic medium comprises a support, a...

10/06/11 - 20110244598 - Test element having combined control and calibration zone
A test element, for example in the form of an immunological test strip functioning according to the sandwich principle, for the fluorophoric detection of one or more analytes in a sample comprising an analyte detection zone and a combined control and calibration zone. The combined control and calibration zone include...

09/29/11 - 20110236998 - Methods and devices for detection of analytes using bloch surface wave-enhanced diffraction-based sensors
The invention features methods and diffraction-based devices for the detection of specific analytes. The devices of the invention contain a periodic dielectric multilayer, which allows for the propagation of Bloch surface waves (BSWs) at the surface of the multilayer, thereby increasing the sensitivity of the device....

09/29/11 - 20110236999 - Hydrogel nanoparticle based immunoassay
An immunoassay device incorporating porous polymeric capture nanoparticles within either the sample collection vessel or pre-impregnated into a porous substratum within fluid flow path of the analytical device is presented. This incorporation of capture particles within the immunoassay device improves sensitivity while removing the requirement for pre-processing of samples prior...

09/29/11 - 20110237000 - Method for detecting an analyte molecule
The invention relates to a method for detecting the presence or amount of an analyte, said method comprising (a) coupling the analyte to a carrier molecule, wherein the carrier molecule is larger in size, electrically charged and/or polar, to form an analyte:carrier molecule complex; (b) contacting the analyte:carrier molecule complex...

09/15/11 - 20110223690 - Assay
The present invention provides an assay kit for detecting an analyte of interest in a sample. The kit comprises a) a reporter species; b) a labelled species having first and second binding regions, wherein the first binding region is capable of binding to the analyte of interest and the second...

08/25/11 - 20110207237 - Optical fiber probe
A biosensor having an optical fiber having at least one curved portion configured to enhance penetration of evanescent waves; and one or more nanoparticles associated with the optical fiber, and configured to enhance localized surface plasmon resonance....

08/25/11 - 20110207238 - Biological substance analyzing method, and biological substance analyzing cell, biological substance analyzing chip, and biological substance analyzing apparatus employed in the biological substance analyzing method
Detection of detection target substances at a sensor portion is expedited and the efficiency thereof is improved in biological substance analysis, to enable accelerated analysis with high sensitivity. A biological substance analyzing cell equipped with a reaction chamber having a sample supply space, an acoustic matching layer which is provided...

08/18/11 - 20110201132 - Optical detection of label-free biomolecular interactions using microreplicated plastic
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters....

07/28/11 - 20110183439 - Structures incorporating conformationally flexible conjugated polymers and methods of use
Methods, compositions and articles of manufacture involving conformationally flexible conjugated polymers are provided. A structure is provided comprising the conformationally flexible conjugated polymer bound to or associated with at least one member of a binding pair comprising a sensor molecule and a target molecule or the complex they form. The...

07/21/11 - 20110177619 - In vitro diagnostic markers comprising carbon nanoparticles and kits
This invention relates to luminescent markers for in vitro diagnostic applications, and kits using those markers. In some embodiments, those markers comprise luminescent carbon nanoparticles. Some embodiments provide a method for investigating an analyte comprising correlating a marker to the analyte and observing the luminescence from the marker, wherein the...

07/21/11 - 20110177620 - Bioanalytical assay
A nanoparticle having a detectible feature and whose diameter is less than 200 nm, and which is coated with multiple specific binding reactants such that the affinity constant of the nanoparticle towards an analyte exceeds that of free binding reactant towards the analyte and/or the association rate constant between the...

07/14/11 - 20110171754 - Analysis system
An analysis system comprises a sampling cartridge (11) comprising a housing (21, 22) having an inlet (23) for receiving a fluid sample, a sensor (26, 45), and a guide (40, 42) extending between the inlet and the sensor for guiding sample into contact with the sensor. The system also has...

06/23/11 - 20110151584 - Dual path immunoassay device
The systems of the invention include test cells with a first sorbent material defining a first flow path for a solution, a second sorbent material defining a second flow path distinct from the first flow path for a sample, and a test site with immobilized antigens or antibodies or other...

06/23/11 - 20110151585 - Dual inlet microchannel device and method for using same
A dual inlet microchannel device and a method for using the device to perform a flow-through kinetic assay are described. A microplate having an array of the dual inlet microchannel devices and in particular their specially configured flow chambers is also described. Several embodiments of the dual inlet microchannel devices...

06/16/11 - 20110143458 - Test device for membrane assay comprising reference display section
A test device provided with a reference display section that rapidly and clearly indicates proper test completion with improved accuracy and stability is provided. Such test device is a test device for membrane assay using a specific binding reaction of a substance to be detected with a capture reagent immobilized...

06/09/11 - 20110136262 - Integrated microchip sensor system for detection of infectious agents
An integrated multiplexed acoustic wave biosensor chip system with enhanced sensitivity has been developed. The biosensor system incorporates one or more microfluidic channels, coated with target-specific binding films enabling rapid and early detection of viral, bacterial or parasitic targets such as Dengue virus and sexually transmitted diseases in specimens from...

06/09/11 - 20110136263 - Microbead analysis method and microbead analyzer
Provided is a microbead analysis method for a microbead. The microbead is formed in a columnar shape having a top surface and a bottom surface facing each other, as placed almost in parallel, and a side surface extending therefrom, and carries an identification pattern formed on at least one of...

06/09/11 - 20110136264 - Method for detecting target substance and target-substance detection kit
and the target substance borne by the magnetic label is captured by a primary capturing body borne by the detecting part, or the target substance captured by a primary capturing body borne by the detecting part is captured by a secondary capturing body borne by the magnetic label....

05/26/11 - 20110124127 - Methods of quantification for lateral flow devices
The invention concerns methods of quantification of an analyte, A, in a test sample by means of a single immunochromatographic device, such as a lateral flow device (LFD). One method comprises the steps of: a) mixing a determined amount of said test sample with a determined amount of a quantification...

05/26/11 - 20110124128 - Centrifugal force based microfluidic system and method for the automated analysis of samples
Centrifugal force based microfluidic systems for the automated analysis of fluids involving the use of magnetically responsive particles and methods thereof are disclosed. A magnet is fixed to a supporting device of the system in correspondence to a retention zone of the system so as to rotate therewith and to...

05/26/11 - 20110124129 - Methods and systems to control fluid flow in accordance with a predetermined sequence
Methods and systems to perform sequential user-controlled fluidic assays, using substantially self-contained, portable, user-initiated fluidic assay systems, including user-initiated activation methods and systems....

05/26/11 - 20110124130 - Device and method for analysis of samples with depletion of analyte content
A system and method for determining the presence and/or concentration of one or more analytes in a sample that comprises a fluid, the system comprising a substrate comprising a sample inlet or inlets and one or more analyte determination flow paths, each analyte determination flow path comprising a defined beginning...

05/19/11 - 20110117672 - Magnetic immunochromatographic test method and device
Method for detecting and quantifying an analyte in a liquid sample, using a test strip and magnetic particles as a detectable label and based on the detection of an amount of magnetic particles which become bound to a reading zone of a test strip as a result of performing the...

05/19/11 - 20110117673 - Methods and systems to collect and prepare samples, to implement, initiate and perform assays, and to control and manage fluid flow
Methods and systems to related to sample collection, assays, and fluid control and management. Methods and systems disclosed herein, and portions thereof, may be implemented alone and/or in various combinations with one another....

05/19/11 - 20110117674 - Assay method and device
A method for the analysis of at least two analytes in a liquid sample, in which a substrate is provided wherein at least two different types of capturing molecules are immobilized on the substrate and wherein each type of capturing molecule has specific affinity for an analyte. The sample is...

05/19/11 - 20110117675 - Substance immobilizing apparatus, substance detecting apparatus and substance immobilizing method
The efficiency of the specific binding of a target substance to an immobilization region is increased. As a first step, target substance 1001 is drawn to immobilization region 1003 on which immobilized substance 1002 to which target substance 1001 can specifically bind is immobilized. As a second step, only target...

05/19/11 - 20110117676 - Magnetic sensor, production method of the same, and target substance detecting apparatus and biosensor kit using the same
The present invention provides a magnetic sensor which detects a target substance indirectly by making a labeling substance larger than the target substance bond with the target substance contained in a sample in a detection area, and detecting the labeling substance, comprising a capture area which is relatively easy to...

05/12/11 - 20110111531 - Method and unit for detection of interactions of biologically relevant molecules
the area on the left and the area on the right of the axial center, which are defined by the inner side of the hollow holder and the external side of the carrier-supporting member on which the carrier has been mounted, are approximately the same within the region from the...

05/05/11 - 20110104824 - Multi-channel saw sensor chip
A sensor chip for specific analysis of analytes in a liquid includes a plurality of sensor elements based on the SAW principle and applied as layer structures onto a surface of a substrate. A surface of each sensor element is coated with a sensitive substrate or coating having receptors specifically...

04/28/11 - 20110097820 - Swab-based diagnostic systems
A diagnostic test system for detecting the presence or absence of an analyte within a test sample is provided. For instance, the system may include a swab and a detection unit. The detection unit includes a first component that is capable of receiving the swab, the first component defining an...

04/14/11 - 20110086438 - Biosensor utilizing a resonator having a functionalized surface
Systems and methods for detecting the presence of biomolecules in a sample using biosensors that incorporate resonators which have functionalized surfaces for reacting with target biomolecules. In one embodiment, a device includes a piezoelectric resonator having a functionalized surface configured to react with target molecules, thereby changing the mass and/or...

03/24/11 - 20110070664 - Integrated microfluidic device for serum biomarker quantitation using either standard addition or a calibration curve
Apparatus and method for determining concentration of one or more target compounds in a sample solution containing one or more nontarget compounds that uses an affinity column to immobilize the target compounds. The target compounds are eluted and passed through a separation/detection system to determine quantitative measure of concentration for...

03/10/11 - 20110059556 - Rapid and continuous analyte processing in droplet microfluidic devices
The compositions and methods described herein are designed to introduce functionalized microparticles into droplets that can be manipulated in microfluidic devices by fields, including electric (dielectrophoretic) or magnetic fields, and extracted by splitting a droplet to separate the portion of the droplet that contains the majority of the microparticles from...

03/03/11 - 20110053292 - signal amplification technique for mass analysis
There is provided a novel method for amplifying mass spectrometric signals. More particularly, a novel method for detecting signals of a target molecule includes: i) allowing a test sample, in which it is required to determine whether or not a target molecule is present, to be contact with a gold...

02/10/11 - 20110033952 - Sensor for biomolecules
A sensor for biomolecules includes a silicon fin comprising undoped silicon; a source region adjacent to the silicon fin, the source region comprising heavily doped silicon; a drain region adjacent to the silicon fin, the drain region comprising heavily doped silicon of a doping type that is the same doping...

02/10/11 - 20110033953 - Characterization of reaction variables
A microscale method for the characterization of one or more reaction variables that influence the formation or dissociation of an affinity complex comprising a ligand and a binder, which have mutual affinity for each other. The method is characterized in comprising the steps of: (i) providing a microfluidic device comprising...

02/03/11 - 20110027913 - Multiplexed nanoscale electrochemical sensors for multi-analyte detection
Provided are nanoscale devices suitable for multiplexed, parallel detection of multiple analytes and methods for fabricating such devices....

02/03/11 - 20110027914 - Sample plate systems and methods
A sample plate comprising a sample well is disclosed. The sample well can comprise one or more bead retaining chambers. Also provided herein is a method of using the sample plate and kits comprising the sample plate....