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Chemistry: Analytical And Immunological Testing > Involving Diffusion Or Migration Of Antigen Or Antibody

Involving Diffusion Or Migration Of Antigen Or Antibody

Involving Diffusion Or Migration Of Antigen Or Antibody patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

04/19/07 - 20070087451 - Immuno-gold lateral flow assay
A chromatographic lateral-flow assay system for rapid, high sensitivity method of detecting low levels of ligands in body fluids, with few false positives and few false negatives. The lateral-flow assay may have a membrane strip in ribbon form, which increases detection on the order of 2 to 10 fold over ...

04/19/07 - 20070087450 - Immuno-gold lateral flow assay
A chromatographic lateral-flow assay system for rapid, high sensitivity method of detecting low levels of ligands in body fluids, with few false positives and few false negatives. The lateral-flow assay may have a membrane strip in ribbon form, which increases detection on the order of 2 to 10 fold over ...

03/22/07 - 20070065952 - Multi-directional immunochromatographic assays
Methods for quantitatively measuring the amount of one or more analyte(s) of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where ...

03/08/07 - 20070054414 - Device and methods for detecting an analyte in a sample
Disclosed is a device, for detecting an analyte in a sample, comprising a sample pad for collecting the sample, a test strip coupled to the sample pad, and a housing enclosing and allowing visualization of the test strip. The sample pad can include one or more markings for determining the ...

03/01/07 - 20070048878 - Diagnostic sanitary test strip
An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test ...

02/22/07 - 20070042504 - Method for determining substance or substances in liquid sample
Disclosed are the methods for the detection and/or quantification of an analyte in liquid sample. The same principle can be applied in the case of detection and/or quantification of more than one analyte present in the sample. Devices of the invention include a sample application zone, a mobilization zone containing ...

02/15/07 - 20070037296 - Combined chemical and immunochemical fecal occult blood test
Methods and systems for performing an immunochemical FOBT following a positive chemical FOBT are disclosed. ...

02/15/07 - 20070037295 - Method for preparing a sample
The present invention relates to a method for reducing the solvent content of a sample in a microchannel or other microfluidic structure comprising the steps of 1) freezing said sample and 2) exposing the frozen sample to a low solvent vapour pressure atmosphere. ...

02/08/07 - 20070031978 - Diagnostic device
A diagnostic device 1 for performing an immunochromatographic analysis of a sample is disclosed. The diagnostic device 1 comprises a porous substrate 10 for performing the analysis and a pre-filter 30 to remove solid components, such as solublised faeces or samples containing suspended organic material to prevent blocking of the ...

01/25/07 - 20070020769 - Immunoassay device for diagnosing congestive heart failure and predicting mortality in congestive heart failure patients
An immunochemical assay device for determining the presence of NT-proBNP alone or conjunctively with Cardiac Troponin I comprising a base member, an array disposed on the base member, and at least one assay indicia zone. The array comprises (i) a reservoir pad to receive sample liquid, (ii) a wicking membrane, ...

01/25/07 - 20070020768 - Two step lateral flow assay methods and devices
Lateral flow assay devices and methods for detecting a first member of a specific binding pair in a sample which comprises a plurality of nonspecific binding pair members are adapted for two step determinations. In one embodiment, a two step lateral flow assay method for identifying IgE antibodies in a ...

01/18/07 - 20070015291 - Rapid test for glycated albumin in blood
This invention describes a rapid assay for measuring the ratio of glycated albumin to total albumin in blood. Patients with diabetes have elevated levels of glucose in their blood that can react with plasma albumin to form glycated albumin. The amount of glycated albumin formed is directly correlated with the ...

01/18/07 - 20070015290 - Assay
The present invention provides an assay kit for detecting an analyte of interest in a sample. The kit comprises a) a reporter species; b) a labelled species having first and second binding regions, wherein the first binding region is capable of binding to the analyte of interest and the second ...

12/28/06 - 20060292701 - Photocrosslinked hydrogel blend surface coatings
Hydrogel polymer blends including precursors and crosslinked forms of the compositions. The blends provide an improved approach to achieve high quality, uniform coatings with better commercial viability than other approaches including copolymerization. Applications include mass spectral analysis of biomolecular analytes such as proteins. Dextran and acrylamide systems are preferred. Benzophenone ...

12/28/06 - 20060292700 - Diffused interrupted lateral flow immunoassay device and method
A lateral flow chromatographic immunoassay rapid test device having an additional interrupting, porous, diffusive pad pretreated with a surfactant interposed between the conjugate pad and the reaction membrane. The diffusive pad causes improved mixing of the fluid to provide a more mixture of molecules in the fluid and a more ...

12/21/06 - 20060286679 - Immunochromatographic method
An immunochromatographic method comprising: (1) preparing a sample derived from whole blood by hemolysis of the whole blood and a treatment for enabling chromatographic development, (2) developing the resulting sample on an immunochromatographic developing membrane, and (3) developing a washing liquid on the immunochromatographic developing membrane to thereby remove an ...

12/14/06 - 20060281193 - Non-optical reading of test zones
A test zone is read. Conjugate material is exposed to a sample. The conjugate material, when conjugated with at least one analyte in the sample, forms either electrically detectable conjugated material or magnetically detectable conjugated material. Conjugated material in the sample is captured in a test zone. A test is ...

12/07/06 - 20060275922 - Lateral flow immunoassay device and method
A lateral flow immunoassay test device is provided that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one immunoassay test strip therein; a first chamber for storing a first, pre-treatment reagent; and a second chamber for storing ...

12/07/06 - 20060275921 - Biosensor
A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an inspection target solution is applied or the downstream of the sample application area ...

12/07/06 - 20060275920 - Apparatus and method for discriminating among lateral flow assay test indicators
An apparatus for analyzing a lateral flow test strip having a plurality of types of markers for binding to analytes corresponding, respectively, to the types of markers. The apparatus includes a plurality of emitters corresponding, respectively, to the plurality types of markers on the lateral flow test strip. Each emitter ...

11/30/06 - 20060270061 - Method for measuring surface plasmon resonance
It is an object of the present invention to provide a measurement method which can suppress noise when a specific binding reaction between a physiologically active substance and a test substance is measured using a surface plasmon resonance measurement device. The present invention provides a method for measuring a change ...

11/30/06 - 20060270060 - Rapid test for glycated albumin in saliva
This invention describes a rapid immunochromatographic assay for measuring the ratio of glycated albumin to total albumin in saliva. Patients with diabetes have elevated levels of glucose in their blood that can react with plasma albumin to form glycated albumin. The amount of glycated albumin formed is directly correlated with ...

11/16/06 - 20060258020 - Sanitary utensil with functions of immuno-chromatographic test and indication
The present invention discloses a sanitary utensil with functions of immuno-chromatographic test and indication, which comprises at least one immuno-chromatographic test piece and at least one cover having an open end. The immuno-chromatographic test piece further comprises a test starting portion, an indicating portion and a test stopping portion. Furthermore, ...

11/09/06 - 20060252158 - Sample recovery method and device
A surface plasmon resonance (SPR) assay apparatus has a sample recovery device for recovering a bindable sample, which is obtained from a sample by causing a sample fluid of the sample to contact an immobilization film provided with a ligand immobilized thereon, and by binding the sample with the ligand. ...

11/02/06 - 20060246601 - Assay devices having detection capabilities within the hook effect region
A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effect” region. Based on ...

11/02/06 - 20060246600 - Metering technique for lateral flow assay devices
A diagnostic test kit for detecting an analyte residing in a test sample is provided. The kit employs a lateral flow device that contains a membrane. A metering channel is formed in the membrane that is capable of delivering a controlled volume of the test sample to a detection zone ...

11/02/06 - 20060246599 - Lateral flow device
A lateral flow device, and related systems and methods is disclosed. A method of building a lateral flow immunoassay device comprises dispensing, via a fluid ejection device, a flow-inducing substance to form a flow membrane, and dispensing, via the fluid ejection device, a measured volume of biosubstances from an array ...

10/26/06 - 20060240569 - Semi-quantitative immunochromatographic device
The invention provides a device comprising one or more support materials capable of providing lateral flow. The one or more support materials contain an area for a receiving a biological sample containing a target analyte, an area having a movably contained detector ligand capable of forming a complex with the ...

10/26/06 - 20060240568 - Assay test strips and reading same
An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at ...

10/26/06 - 20060240567 - Method of immobilizing a protein to a zeolite
The present invention relates to a polypeptide tag and a method using said polypeptide tag sequence for immobilizing a protein on a microporous material, said microporous material is selected from the group consisting of zeolite or similar solid surfaces whereby loss of activity of said protein is less than 10% ...

10/05/06 - 20060223194 - Methods of screening for post-translationally modified proteins
The invention provides methods of analyzing a sample. In general, the methods involve: a) depositing sub-fractions of a multi-dimensionally fractionated sample into wells of a multi-well substrate; b) contacting each of the deposited sub-fractions with an array to produce a set of sub-fraction-contacted arrays; and c) interrogating the sub-fraction-contacted arrays ...

10/05/06 - 20060223193 - Diagnostic test kits employing an internal calibration system
A diagnostic test kit that employs a lateral flow assay device and a plurality of assay reagents for detecting a test analyte within a test sample is disclosed. The assay reagents include detection probes that are capable of producing a detection signal representing the presence or quantity of the test ...

10/05/06 - 20060223192 - Rapid test for glycated albumin
A rapid immunochromatographic assay system is provided for measuring the amount of glycated albumin in a blood sample relative to the total level of albumin in the sample. The assay system is comprised of a disposable cassette that contains the test strips and testing reagents, and a measurement device that ...

09/28/06 - 20060216834 - Assay devices that utilize hollow particles
Hollow particles for use in various types of assay devices are provided. Due to their hollow or voided structure, the particles may exhibit a variety of beneficial properties. For instance, hollow particles are generally lightweight, and thus, relatively inexpensive in comparison to other types of particles. Hollow particles may also ...

09/28/06 - 20060216833 - Spot test kit for explosives detection
An explosion tester system comprising a body, a lateral flow membrane swab unit adapted to be removeably connected to the body, a first explosives detecting reagent, a first reagent holder and dispenser operatively connected to the body, the first reagent holder and dispenser containing the first explosives detecting reagent and ...

09/28/06 - 20060216832 - Reader for immunochromatographic test, cartridge applicable to this, and system for examining immunochromatographic test piece
The present invention relates to an immunochromatographic test reader, etc., having structures that enable accommodation of a plurality of immunochromatographic test utensils that differ in outer shape and enable immunochromatographic test utensils to be managed readily in association with information concerning the immunochromatographic test utensils. The reader has a structure ...

09/21/06 - 20060211135 - Method and apparatus for separating molecules using micro-channel
A method for simply and efficiently separating substances by utilizing a specific flow behavior in a non-turbulent flow, i.e. a laminar flow, in a micro-channel is disclosed. A mixed solution containing at least two kinds of solute molecules which are different from each other in molecular weight and/or molecular sharp, ...

09/14/06 - 20060205088 - Agglutination assay method in porous medium layer
An agglutination assay method for quantitatively determination of an analyte in an aqueous liquid sample using particles bearing an anti-analyte. The agglutination is conducted in the porous medium layer of the analysis element A speedy quantitative analysis of the analyte can be conveniently attained with high sensitivity. When the particle-labeled ...

09/14/06 - 20060205087 - Lateral flow devices using reactive chemistry
There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a wicking pad. The porous membrane has a detection zone which has a chromophore configured ...

09/14/06 - 20060205086 - Diagnostic device
A diagnostic device for testing a liquid sample has a carrier for receiving at least a portion of the sample and a sample delivery means. The sample delivery means has a delivery channel that is in fluid communication with the carrier. The delivery channel has a first delivery channel surface ...

09/07/06 - 20060199278 - Double-sided device for multiplex dipstick immunodiagnostic
The present invention relates to methods and devices for detecting one or more analytes or analyte products in a biological sample. This invention in particular relates to improved rapid tests such as “dipsticks” and “lateral flow” devices. The invention in particular relates to chromatographic device made of two active sides, ...

09/07/06 - 20060199277 - Devices and methods for analyte assays with built-in result reporting using recognizable symbols
The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample and indicating to the user the presence or absence of the analyte through the formation of a recognizable symbol during the assay. In one embodiment, the present invention provides test strips ...

09/07/06 - 20060199276 - Device for multiple rapid detection and testing of diseases, disorders and immunity in human, animals and the environment
According to the invention there is provided a device for testing for diseases disorders and immunity in humans, animals and the environment, which includes a bottom membrane support assembly having a lower opening and operative to receive a bottom membrane extending over said lower opening and a top membrane support ...

08/03/06 - 20060172435 - Non-continuous immunoassay device and immunoassay method using the same
A non-continuous immunoassay device which includes two or more separated pads for immunoassay analysis, and is capable of controlling the migration speed of a mobile phase between the separated pads, and an immunoassay method using the same are disclosed. The immunoassay device includes a first pad receiving a mobile phase; ...

08/03/06 - 20060172434 - Surface layer affinity-chromatography
There is described an affinity-chromatography assay system comprising with an immobilised component containing a bio-reagent and a flowable component containing a complimentary bio-reagent characterised in that the immobilised component is supported on a dip strip or planar surface and the flowable component is adapted to flow down the dip strip ...

07/27/06 - 20060166374 - Method for the visual detection of specific antibodies by the use of lateral flow assays
This disclosure teaches a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, haptens, and carbohydrates by lateral flow techniques. In one embodiment of the disclosure, a test sample is added to the test strip, which then ...

07/06/06 - 20060148097 - Test strip for immunochromatography
A test strip for immunochromatography comprising a sample receiving member, a label holding member, and a chromatography membrane is described. The chromatography membrane has a first detection zone and a second detection zone. The second detection zone is formed by utilizing a blocking material and the second substance. A method ...

07/06/06 - 20060148096 - Assay device, system and method
A system for treating a blood sample (700) having an analyte of interest comprises a strip (200) having a membrane (218), respective portions (216, 220 and 222, or 300) which are provided for receiving the sample, for lysing cells of the sample to liberate hemoglobin, and for capturing glycated hemoglobin. ...

07/06/06 - 20060148095 - Method for high-throughput integrated chemical and biochemical reactions
The present invention relates to methods for monitoring in a high through-put fashion a multitude of molecular reaction processes, using a substrate, said substrate comprising a plurality of micro-channels, wherein each micro-channel has inlet and outlet open ends on opposing sides of said substrate, and wherein said micro-channels comprise at ...

06/29/06 - 20060141639 - Positive detection lateral-flow apparatus and method for small and large analytes
Methods and devices for the detection and/or quantification of an analyte in a sample are provided. These are positive detection methods and devices, in that the more analyte is present in the sample, the stronger the signal that is provided. Devices of the invention include a mobilization zone including a ...

06/22/06 - 20060134805 - Purification of immunoglobulins
The present invention relates to a separation matrix comprised of porous particles to which antibody-binding protein ligands have been immobilised, wherein the ligand density is in the range of 5.0-10 mg/ml; the gel phase distribution coefficient of the particles expressed as Kav for a dextran of size 110 kDa is ...

06/22/06 - 20060134804 - Devices and methods for analyte assays with built-in result reporting using recognizable symbols
The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample. The invention provides devices having a positive control area covered with an opaque, movable material, such as an ink, dye, or other material, that is moved on the device by the ...

06/22/06 - 20060134803 - Immunoassay devices and use thereof
An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site with immobilized antigen or antibody for the ligand to be tested, and a filter for filtering ...

06/22/06 - 20060134802 - Solid-phase immunochromatographic methods
The invention concerns solid-phase immunochromatographic methods for detecting an analyte in a liquid sample. In the inventive methods, a binding reagent conjugated with a particulate marker is extemporaneously added in liquid form. ...

06/15/06 - 20060128029 - Method for the determination of an analyte in a liquid
A method is provided to determine the presence of an analyte in a sample. The method provides an element with a sample application zone, a detection zone, a zone containing immobilized analyte or analyte analogue, a conjugate that has a first bioaffine binding partner capable of a specific binding reaction ...

06/08/06 - 20060121626 - Diagnostic assay device
This invention relates to assays for an analyte in a liquid sample such as a body fluid. More particularly, the invention relates to a method and apparatus for the detection of a ligand in a body fluid such as urine or blood, which includes an immobilization zone for interfering agents ...

06/08/06 - 20060121625 - Measuring apparatus used for determining an analyte in a liquid sample, comprising polymer electronic components
So that the analyte can be determined in a straightforwardly, conveniently and inexpensively, at least some of the electrical apparatus components (5 to 12) are formed on the basis of polymer electronics. ...

05/18/06 - 20060105470 - Method and apparatus for detecting conception in animals
The present invention provides antibodies which specifically bind early conception factor, which can be found in body fluids of animals including but not limited to the cow, cat, dog, horse, human, sheep, and pig. The invention provides methods for detecting conception or the absence of conception in an animal, the ...

05/18/06 - 20060105469 - Assay devices
Assay devices are disclosed comprising a base defining a cavity and an insert received in the cavity. The cavity has major surface and at least one sidewall, preferably surrounding the major surface. The insert comprises a first surface with a portion opposing the major surface of the cavity. A space ...

05/11/06 - 20060099719 - Biochemical assay
A biochemical assay is provided comprising a substrate being capable of binding at least a target analyte and eventually other constituents contained in a biological sample, a test zone on the substrate for sample application, a non-immobilized conjugate reagent provided in the test zone for labelling the analyte, the conjugate ...

03/30/06 - 20060068501 - Apparatus and methods for steroid hormone testing
An immuno-chromatographic detection device for detecting an analyte in sample, such as estrogen in a urine or saliva sample, the device comprising (a) a binding membrane having immobilized thereon (i) an test antibody against said analyte in at least one detection region, and (ii) a control antibody against a control ...

03/30/06 - 20060068500 - Detecting yeast infections using a lateral flow assay
There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in liquid communication with a conjugate pad and a wicking pad. The conjugate pad has a gold colloid-containing ...

03/16/06 - 20060057739 - Method of identification and quantification of proteins, isoforms of the angiotensin i converting enzyme
The present invention relates to a method of identification and quantification of proteins, isoforms of angiosttensin I converting enzymes (ACE), 190-kDa, specially of 90 kDa in tissues, cells and biological fluids, specially in urine, genetic marker and prognostic agent of hypertension and primary or secondary renal lesion and kit for ...

03/02/06 - 20060046310 - Amplification method for solid phase immunoassays
The present invention is directed to immunoassays for detecting one or more target analytes in a fluid sample wherein the detection reaction occurs on a solid support and involves an amplification system. In particular, the invention is directed to making and using a test device having at least one site ...

02/23/06 - 20060040406 - Narcotic analgesic tracking system
A device and method for testing the contents of a sample of a controlled substance to confirm the presence or absence of the controlled substance within that sample. In one implementation, the device and method utilize antibodies designed to interact with one or more anesthetics, e.g., opioid analgesics. The antibodies ...

02/16/06 - 20060035386 - Fine particle handling unit, chip and sensor mounted with same, and methods for separating, capturing and sensing protein
A channel (1) formed in a substrate (41) branches into channels (2, 3) at a branch point (43). On this branch point, obstacles (8) having a columnar structure are aligned at certain intervals. ...

02/02/06 - 20060024843 - Assay device
A device for carrying out a lateral flow assay on a sample comprising: (a) a sample containing unit comprising a sample container, said sample container being closed off at one end by a bottom wall, said bottom wall having a hole sealed by a plug; and (b) a housing located ...

02/02/06 - 20060024842 - Portable diagnostic device and method for determining temporal variations in concentrations
A rapid assay concentration device. In one form, the device includes a substrate and a plurality of elongated membranes on the substrate. At least one capture zone is formed in each membrane. Each capture zone is responsive to the presence of a target chemical in the fluid. Capture zones on ...

01/26/06 - 20060019407 - Immunoassay assembly and methods of use
The present invention relates to an improved system for efficiently and accurately performing immunoassays, such as ELISAs. The invention provides an immunoassay assembly which includes a flow-through unit and an aspiration pump. The immunoassay flow-through unit includes an outer seal; at least one bed support; an inner seal; and a ...

01/26/06 - 20060019406 - Lateral flow device for the detection of large pathogens
There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a conjugate pad and a wicking pad. The porous membrane has a detection zone where ...

01/26/06 - 20060019405 - Cat lavator comprising an urine test
The present invention relates to a cat lavatory including at least one absorbent material comprising an insert of non-woven material, at least one indicator strip for determining a cat's urine levels, which is arranged on and/or in the absorbent material; and a method of determining a cat's urine levels using ...

01/12/06 - 20060008921 - Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
Immunochromatographic test strip assays which employ semiconductor nanocrystals as detectable labels are disclosed, as are methods for detecting and quantifying one or more analytes of interest in a test sample using those assays. The test strips of the present invention permit detection and quantitation of one or more analytes of ...

01/12/06 - 20060008920 - Combination assay for alcohol and drugs of abuse
A test apparatus that allows testing for the presence of both drugs of abuse and alcohol within a single device. In general, the apparatus of the present invention includes a lateral flow immunoassay screening for various drugs of abuse and a reactive pad including an enzyme as a test for ...

12/22/05 - 20050282294 - Affinity supports with immobilised protein a
The present invention relates to affinity supports with immobilised, covalently bonded protein A, which have a particularly high functional efficiency, wherein protein A is bonded to the support via an aminocarboxylic acid as spacer, to the preparation thereof, and to the use thereof in the purification and analysis of antibodies ...

12/15/05 - 20050277202 - Collection device for lateral flow chromatography
A device for collecting oral liquids includes a lateral flow chromatography strip having a collection member. The collection member is separated from the remainder of the chromatography strip by a liquid impermeable removable barrier which prevents liquid in the collection member from entering the chromatography strip. Once adequate oral liquid ...

12/08/05 - 20050272169 - Device for chemical or biochemical analysis
A device for analysis of a sample, the device comprising: a first layer having a network of passages and chambers through which fluid is caused to flow during analysis; a second layer in which a plurality of chambers are formed, the chambers containing fluids for use in the analysis; an ...

11/17/05 - 20050255608 - Bulking materials containing starch reagent for use in test devices
The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having starch reagents effectively enhance chromatographic detection methods by providing component stability and controlled release. Thus, the novel components and methods disclosed herein provide a completely ...

11/03/05 - 20050244986 - Assays
An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with the exterior of the casing via a bibulous sample receiving member (506) which protrudes from the ...

11/03/05 - 20050244985 - Chromatographic assay device and methods
A chromatographic assay device for the analysis of an analyte in a liquid sample has a proximal sample application zone and a distal test zone. The test zone contains a first ligand capable of binding with the analyte to form an analyte-ligand complex. The device also includes a spatially distinct ...

10/27/05 - 20050239214 - Non-sugar sweeteners for use in test devices
The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners effectively enhance chromatographic detection methods by providing component stability and controlled release. Thus, the novel components and methods disclosed herein provide a completely ...

10/13/05 - 20050227372 - Diagnostic test kit
A diagnostic test kit comprising test strips, extraction instrument, reagent material, all in an elongated tubular container. ...

10/13/05 - 20050227371 - Hybrid phase lateral flow assay
The invention relates to devices for performing single step assays for the determination of the presence or absence of an analyte in a liquid sample, and methods of determining the presence or absence of such analytes using such devices. Devices disclosed comprise a labeled analyte-binding reagent reversibly-immobilized on a non-porous ...

10/13/05 - 20050227370 - Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
A combination body fluid analyte meter and cartridge system, having: (a) a body fluid analyte meter, with: a housing; a logic circuit disposed within the housing; a visual display disposed on the housing; and a measurement system disposed within the housing; and (b) a cartridge, having: at least one lateral ...

10/06/05 - 20050221502 - Assay system and method for direct measurement of ldl cholesterol
An assay device and method for measuring the concentration of LDL-associated cholesterol in a blood-fluid sample are described. The method employs selective precipitation of VLDL and chylomicrons and immunoseparation of HDL from a blood fluid sample. The assay device allows the assay to be performed entirely in a flow strip ...

09/29/05 - 20050214951 - Lateral flow quantitative assay method and strip and laser-induced fluoerescence detection device therefor
Disclosed is a lateral flow quantitative assay method which can measure one or more analyte species at the same time, with high sensitivity. Also, the present invention relates to a strip which can measure one or more analyte species at the same time, with high sensitivity and a package in ...

09/22/05 - 20050208677 - Lateral flow test strip
The present invention provides a test strip having a first layer comprising a wicking member and a second layer comprising a capillary transfer plane member. The capillary transfer plane has a plurality of capillary transfer passages. The capillary transfer passages can comprise various shapes to control sample flow rate. Located ...

09/08/05 - 20050196875 - Dry reagent particle assay and device having multiple test zones and method therefor
The disclosure relates to a dry reagent assay device having two or more test zones for detecting two or more analytes in a test sample. In one embodiment, the test zones may be the site of a binding reaction between members of a binding pair, or they may be the ...

08/18/05 - 20050181521 - Sampling and assay device together with methods for use thereof
An immunochemical sampling device, kits including the sampling device, processes for production of the sampling device, and methods for use of the sampling device in lateral flow immunoassays. The sampling device comprises a solid support that is partially wrapped in a porous carrier, then covered in a hydrophobic cover. At ...

08/04/05 - 20050170527 - Quantitative lateral flow assays and devices
This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complementary specific binding pair members for the analyte and a novel arrangement ...

08/04/05 - 20050170526 - Mass spectrometric immunoassay
Rapid mass spectrometric immunoassay methods for detecting and/or quantifying antibody and antigen analytes utilizing affinity capture to isolate the analytes and internal reference species (for quantification) followed by mass spectrometric analysis of the isolated analyte/internal reference species. Quantification is obtained by normalizing and calibrating obtained mass spectrum against the mass ...

08/04/05 - 20050170525 - Method and apparatus for analyzing amino acid, peptide, protein, saccharide or lipid
The present invention aims to easily and simply perform selective detection/identification, extraction, separation, and purification of a phosphorylated amino acid, phosphorylated peptide, or phosphorylated protein from a sample containing any one of them, comprising the steps of: retaining the phosphorylated amino acid, phosphorylated peptide, or phosphorylated protein in a pretreatment ...

07/28/05 - 20050164406 - Diagnostic sanitary test strip
An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test ...

07/28/05 - 20050164405 - Non-specific bridge link specific sandwich immuno-complex to the solid phase in the lateral flow immunoassay
A chromatographic immunoassay test strip comprising of a solid support having the portions with said portions being in a strip so as to permit capillary flow communication with each other based on the principle of “Bridge-Sanwhich”. In this chromatographic immunoassay test strip herein the analyte in the sample reacts with ...

07/28/05 - 20050164404 - Diagnostic testing process
A method and apparatus for use in a flow through assay process is disclosed. The method is characterised by a “pre-incubation step” in which the sample which is to be analysed (typically for the presence of a particular protein), and a detection analyte (typically one or more antibodies bound to ...

07/07/05 - 20050148097 - Instruments for detecting low-molecular weight substance
To provide the following instruments 1 and 2 as a low-molecular-weight substance detection instrument employing immunochromatography capable of detecting conveniently and sensitively detecting a low-molecular weight substance such as an environmental pollutant (e.g., a dioxin), as a target substance contained in a test sample: 1. an instrument, which comprises 1) ...

06/23/05 - 20050136552 - Diagnostic devices and apparatus for the controlled movement of reagents without membranes
The assay devices, assay systems and device components of this invention comprise at least two opposing surfaces disposed a capillary distance apart, at least one of which is capable of immobilizing at least one target ligand or a conjugate in an amount related to the presence or amount of target ...

06/23/05 - 20050136551 - Micro mechanical methods and systems for performing assays
The present invention provides a micro mechanical system for performing assays for determining the presence of one or more selected analytes in a sample. The device comprises of a base and a disposable strip with at least one reaction well and at least one moveable member capable of moving fluids ...

06/23/05 - 20050136550 - Flow control of electrochemical-based assay devices
Various techniques for controlling the flow of a test sample through an electrochemical-based assay device are provided. The assay device contains a porous membrane provided with certain properties to selectively control the flow of a test sample to a detection working electrode. The detection working electrode communicates with affinity reagents, ...

06/16/05 - 20050130319 - Molecular binding event detection using separation channels
Detecting binding events between first and second molecules (e.g., ligands and proteins) includes mixing at the first end of a test channel, then separating the bound/unbound molecules (e.g., using electrophoresis) by causing the molecules to move down the channel such that groups of bound/unbound molecules move along the channel at ...

06/09/05 - 20050124076 - Method for screening autoantigen
The present invention relate to an autoantigen screening method by combining immunoaffinity chromatography, disease-related cell lines, and mass spectrometry technology, which offers greater screening efficiency and speed than known technologies. The method for screening autoantigen by using autoantibodies in patient's body by utilizing the chromatographic column packed with autoantibodies, through ...



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