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Chemistry: Analytical And Immunological Testing > Including Sample Preparation > Volumetric Liquid Transfer

Volumetric Liquid Transfer

Volumetric Liquid Transfer patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

04/05/07 - 20070077663 - Batch reactor with injection system
An apparatus and method for injection of one or more chemical components into a reaction chamber are disclosed. The apparatus includes a reaction chamber for receiving one or more libraries in a fixed position relative to the chamber and configured to form a sealed enclosure. An injection manifold is located ...

03/08/07 - 20070054413 - Method for obtaining sample material
A sample carrier comprising a frame and one or more sample tube receiving structures pivotally connected to the frame. Each sample tube receiving structure includes a bottom member adapted to receive a plurality of sample tubes and a top member having a plurality of aligned apertures sized to receive sample ...

02/22/07 - 20070042503 - Moving microdroplets
The movement and mixing of microdroplets through microchannels is described employing microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to ...

02/15/07 - 20070037294 - Methods for performing microfluidic sampling
Methods for performing microfluidic sampling are provided. The method includes providing a substrate including an arrangement of first, second and third electrodes, wherein the second electrode is interposed between the first and third electrodes. The method additionally includes causing a fluid input to continuously flow to the first electrode and ...

02/15/07 - 20070037293 - Flow rate control
A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable ...

02/01/07 - 20070026534 - Prediction of aspirated volume of a liquid
Pfinal is final pressure of the volume of gas after the column of liquid has equilibrated, and Volume/unit pressure is the change of the gas volume for each change of unit pressure. In a preferred embodiment, the pressure is expressed in analog/digital counts. In another preferred embodiment, the liquid is ...

01/25/07 - 20070020767 - Processes and devices for the liquid treatment of suspended particles
Processes are described for the treatment of at least one particle (10-13) with at least one reaction liquid (20) in a main channel (30) of a fluidic microsystem (100) with the following steps: movement of the at least one particle (10-13) with a carrier liquid (40) flowing in a longitudinal ...

01/18/07 - 20070015289 - Dispenser array spotting
A method of dispensing a fluid comprising (a) aspirating a first fluid volume into a dispenser adapted to dispense fluid volumes of one microliter or less; (b) dispensing a desired volume of the fluid volume to form a dispensed portion; (c) calculating the volume of the dispensed portion; and (d) ...

12/21/06 - 20060286678 - Pipetting needle
A method and a micropipetting apparatus is described for dispensing a liquid volume into a vessel via pipetting needle without any contact between the needle and a liquid contained in the vessel. The method comprises forming a drop at the delivery tip of the pipetting needle, the drop being retained ...

12/14/06 - 20060281192 - Method for mixing fluids in microfluidic systems
A method for mixing liquids on a microfluidic level comprises the steps of rotating a coupon to impart flow via centripetal force to a first liquid through a microchannel in the coupon to inject the first liquid into a mixing chamber to mix the first liquid with a second liquid, ...

11/30/06 - 20060270059 - Modular printing of biopolymer arrays
Methods and apparatus are disclosed for preparing an array of polymeric compounds on a substrate. Drops of polymer subunits are dispensed to a surface of a substrate from two or more drop dispensing modules wherein each module comprises dispensers for dispensing a respective polymer-forming reagent. At least two of the ...

11/23/06 - 20060263903 - Method for determining diffusivity and molecular weight in a microfluidic device
The present invention is directed to a method for determining the molecular weight and diffusivity of a sample solute by providing a plus shaped microchannel network on a microfluidic chip, having at least four microchannels intersecting at a cross point; flowing a sample stream comprising a sample solute of unknown ...

11/23/06 - 20060263902 - Dispensing of a diagnostic liquid onto a diagnostic reagent
Biological fluid samples are deposited by methods that produce a uniform layer of the sample over a reagent-containing surface. In one embodiment, a nozzle having multiple openings is used to deposit a sample over the reagent-containing surface simultaneously. In an alternative embodiment, single droplets of the sample are deposited in ...

11/16/06 - 20060258019 - Methods and devices for high throughput fluid delivery
Methods and devices for delivering fluids into microfluidic device body structures are described. The methods and devices include the use of fluid manifolds that are integrated or interchangeable with device body structures. Methods of fabricating manifolds are also provided. ...

11/16/06 - 20060258018 - Method and apparatus for determining the area or confluency of a sample
The area or confluency of a sample is determined by obtaining quantitative phase data relating to the sample and background surrounding the sample. The boundary of the sample is determined from the quantitative phase data by forming a histogram of phase data measurements and taking the derivative of the histogram ...

10/26/06 - 20060240566 - Delivery of metered amounts of liquid materials
Techniques for the delivery of metered amounts of liquid material include the use of a pin, such as an optical fiber. A sample of the liquid material may be placed on the tip of the pin for delivery to a target area, such as a specific location on a microarray, ...

10/12/06 - 20060228812 - Micro analysis system
A micro integrated analysis system includes a testing chip, system main body and heat insulating section. The chip has a pump connecting section to communicate with micro pumps; a mixing flow path for mixing a specimen and reagent and for reaction processing by heating; and a testing flow path for ...

09/28/06 - 20060216831 - Methods for automated collection of small volume of liquid
In one embodiment of the invention, methods are provided for collecting the content of microtiter plate well An automated pipett is programmed to aspirate along the wall of a microtiter well at defined intervals to collect liquid that may be on the walls of the well ...

09/21/06 - 20060211134 - Priming module for microfluidic chips
Methods and apparatuses for priming sample substrates such as DNA sipper chips are disclosed. According to one aspect of the present invention, a priming system that is suitable for priming a substrate which has a plurality of wells and at least one channel includes a base unit and a top ...

09/21/06 - 20060211133 - Ultra-low volume fraction collection and analysis
An ultra-low volume fraction collection and concentration method provides practical application in collecting fractions, e.g. as low as 25 nL, from nanoLC columns into pipette tips at user-defined timed-intervals. The fractions are dried to create a concentrated band at the very end of the interior of the pipette tip and ...

09/21/06 - 20060211132 - Method for high throughput drop dispensing of specific patterns
The invention relates to methods and systems for high throughput precision “on-the-fly” dispensing of sub-microfluidic quantities of reagents and other liquids in specific patterns onto or into a target substrate. In certain embodiments, a high speed process is provided for creating and/or repeating spaced lines or line segments by dispensing ...

08/17/06 - 20060183244 - Handling method of body fluid sample and analysis apparatus using the same
Sample sampling to an analysis apparatus 200 or 820 for analyzing a biochemical analysis item is performed by a pipetting device 202 or 840 which uses a repetitively used pipette nozzle, and sample sampling to an analysis apparatus 100 or 810 for analyzing an immune analysis item is performed by ...

08/10/06 - 20060177942 - Handling method of body fluid sample and analysis apparatus using the same
Sample sampling to an analysis apparatus 200 or 820 for analyzing a biochemical analysis item is performed by a pipetting device 202 or 840 which uses a repetitively used pipette nozzle, and sample sampling to an analysis apparatus 100 or 810 for analyzing an immune analysis item is performed by ...

08/10/06 - 20060177941 - Handling method of body fluid sample and analysis apparatus using the same
Sample sampling to an analysis apparatus 200 or 820 for analyzing a biochemical analysis item is performed by a pipetting device 202 or 840 which uses a repetitively used pipette nozzle, and sample sampling to an analysis apparatus 100 or 810 for analyzing an immune analysis item is performed by ...

08/03/06 - 20060172433 - Liquid sampling utilizing ribbed pipette tip for barrier penetration
An apparatus and method for liquid sampling utilizing a ribbed pipette tip for barrier penetration is disclosed herein. The unique, disposable plastic pipette tip of the present invention has an outer surface with at least three ribs extending longitudinally along the outer surface of the barrel. Each rib is circumferentially ...

07/27/06 - 20060166373 - Chemical analysis apparatus and analysis device
There are provided a chemical analysis apparatus and an analysis device in which predetermined quantities of a sample and a reagent are presicely pipetted, then are subjected to various processes, and are tested by a test device. Thus, the chemical analysis apparatus comprises the analysis device, an oil supply portion, ...

07/27/06 - 20060166372 - Method for fillling sample carriers
A method for filling sample carriers with chemical and/or biological liquids can be performed by means of a liquid dispensing device. The liquid dispensing device comprises a liquid chamber. The liquid chamber is acted on by a piezo actors. Through an activating pulse generated by the piezo actor, liquid droplets ...

06/29/06 - 20060141637 - Multi-phase fluid sampling method and apparatus
The invention provides a method for producing a homogenous sample of a pressurized fluid stream flowing in a pipeline, the fluid stream consisting of a majority component of hydrocarbon gas, the remainder consisting of one or more hydrocarbon liquids and water in the form of vapor, aerosols, droplets and/or liquid ...

06/08/06 - 20060121624 - Methods and systems for fluid delivery
The systems and methods herein involve the use of an automated, high-throughput system that utilizes pressure to transfer a fluid medium containing an analyte. In preferred embodiments, the sample is delivered to an analytical device. The sample can comprise one or more analytes, e.g., solvents, solutes, or particles, including rare ...

04/13/06 - 20060079003 - Apparatus and method for a precision flow assay
A flow cell system includes a housing, a mixing chamber and a flow channel sized to provide for movement of liquid from the mixing chamber by non-capillary action. A monitoring device is coupled to the matrix. A fluid moving source is coupled to the flow channel. A matrix is coupled ...

04/06/06 - 20060073609 - Sample supplying method and device
An inlet pipette tip, into which a sample has been sucked, is fitted to an inlet of a flow path member of an analysis unit comprising a dielectric material block having a smooth surface, on which a thin film layer has been formed, and the flow path member, which is ...

03/23/06 - 20060063274 - Methods for manufacturing and using chemical array calibration devices
The invention provides methods for manufacturing a chemical array reader calibration device. Embodiments include dispensing a volume of fluorescent dye coating composition from a pulse jet fluid deposition device onto a surface of a substrate to coat the surface with the fluorescent dye coating composition. Also provided are chemical array ...

03/23/06 - 20060063273 - Separating apparatus, separating method, and mass analyzing system
Individual components are separated with a high concentration and accurately, from a sample containing components-to-be-separated. The separation apparatus includes a channel through which a sample containing components-to-be-separated moves; and gateway portions partitioning the separation channel into a plurality of compartments. The separation apparatus further includes an external force imposing unit, ...

03/23/06 - 20060063272 - Method for characterizing a highly parallelized liquid handling technique using microplates and test kit for carrying out the method
A method for characterizing highly parallelized liquid handling technology using microplates and test kit for carrying out the method. Possibilities for characterizing a multi-channel or many-channel handling technology are known in principle. However, especially with regard to more highly parallelized devices and very small volumes, particularly under conditions corresponding to ...

03/02/06 - 20060046309 - Thromboplastin reagents
A thromboplastin reagent includes tissue factor, Factor VIIa, and a net negatively charged phospholipid. The thromboplastin reagent is a synthetic thromboplastin reagent, and is in dried form. ...

03/02/06 - 20060046308 - Method of reaction utilizing microchannel
A method of chemically reacting two or more reactants which react one another, which comprises fixing molecules of the reactants to fluids and supplying them to a microchannel to efficiently conduct the chemical reaction based on the molecular structure or molecular orientation imparted to the microchannel or on the function ...

02/23/06 - 20060040404 - Inkjet spotting apparatus for manufacturing microarrays and method of spotting using the same
Provided are an inkjet-type spotting apparatus for manufacturing microarrays and a method of spotting using the same. The spotting apparatus includes a plurality of reservoirs which are arranged in rows and filled with a predetermined biomolecule solution; and a plurality of nozzles, each corresponding to one of the reservoirs and ...

02/23/06 - 20060040403 - System and method for providing a reaction using a limited reaction surface area
A method and apparatus for chemical analysis is disclosed that uses a sample cup insert. The insert is pre-coated with a reaction agent, enzyme, or chemical to facilitate testing of the sample. A sample fluid in the sample cup is agitated by fluid pulsing to speed the reaction or to ...

02/02/06 - 20060024841 - Method and apparatus for delivery of submicroliter volumes onto a substrate
A slotted pin tool, a delivery system containing the pin tool, a substrate for use in the system and methods using the pin tool and system are provided. The slotted pin tool contains a plurality of pins having slotted ends designed to fit around each loci of material deposited on ...

12/22/05 - 20050282293 - System for delivering a diluted solution
The invention features methods and devices for the delivery of a fluid medium containing analytes, e.g., particles, solutes, or solvents, to an analytical device. The systems are designed to minimize contact with potentially hazardous, fragile, or valuable samples. The systems allow for the dilution, mixing, and introduction of the fluid ...

12/22/05 - 20050282292 - Automated slide staining apparatus
Disclosed is an automated staining apparatus (autostainer) capable of staining sample on a microscope slide. The autostainer is capable of limiting the amount of reagent used through a process including image acquisition and processing techniques, wherein an image of the slide is acquired and used to determine a region on ...

12/22/05 - 20050282291 - Method for aspiration of a liquid sample
A liquid aspiration method which includes aspirating partial aliquots of liquid at a number of different depths of penetration of a pipette tip into a liquid. The different depths are selected so that partial aliquot segments are obtained throughout the entire depth of sample, optionally excluding the extreme top and ...

12/22/05 - 20050282290 - Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument
The present invention relates to a technique for moving a mobile component such as a sample and a reagent, in an analyzing article. A method of analyzing a sample according to the present invention includes a first movement step of moving a mobile component from a fluid entrance port (61) ...

10/20/05 - 20050233472 - Spotting high density plate using a banded format
A method of dispensing a fluid comprising (a) aspirating a first fluid volume into a dispenser adapted to dispense fluid volumes of one microliter or less; (b) dispensing a desired volume of the fluid volume to form a dispensed portion; (c) calculating the volume of the dispensed portion; and (d) ...

09/22/05 - 20050208676 - Device for aspirating, manipulating, mixing and dispensing nano-volumes of liquids
A pipettor device and pipette tip for aspirating, mixing, manipulating and dispensing nano-volumes of fluid comprising a directed gas flow along the exterior tip surface to assist in dispensing the liquid. ...

09/22/05 - 20050208675 - Method for producing a microarray
A plurality of droplets of a liquid sample containing a biological substance are applied to positions where all the droplets join with one another on a surface of a water repellent substrate by using a microarrayer of the ink-jet type having a jet tip, the microarrayer exerting a pressure on ...

08/25/05 - 20050186685 - Protecting agent
A method for transporting in a microfluidic conduit an aliquot of a liquid, possibly containing a substance I, which is dissolved in the liquid and typically exhibits charged groups and/or hydrophobic groups. The method is characterized in that the liquid contains an amphiphilic macromolecular substance. ...

08/18/05 - 20050181519 - Metering doses of sample liquids
A method of metering and mixing a dose of a sample liquid with a diluent liquid includes introducing a sample liquid into a channel defined in a housing. The housing defines a pocket open to the channel and sized to both collect a metered dose of the sample liquid, and ...

07/28/05 - 20050164403 - Liquid dispensing device
A liquid dispensing device. The liquid dispensing device has a tray for holding a liquid at a relatively constant level. A syringe is used for drawing fluid from the tray. A liquid container containing a liquid is positioned upside-down in the tray such that the opening of the liquid container ...

07/21/05 - 20050158875 - Liquid transfer positioning
A liquid transfer appliance and a well plate are moved towards each other and a current is detected that flows upon contact between the liquid transfer appliance and a first electrically conductive element of the well plate. The position of the well plate relative to the liquid transfer appliance is ...

07/21/05 - 20050158874 - Process vessel with integral evaporator
A process vessel containing both an evaporation zone for evaporating a liquid feed and a treatment zone for treating the resulting vapor comprises an injector having an orifice, the orifice being in the evaporation zone, at least one evaporation surface for evaporating feed and generating vapor, the evaporation surface being ...

07/21/05 - 20050158873 - Process vessel with integral evaporator
A process vessel containing both an evaporation zone for evaporating a liquid feed and a treatment zone for treating the resulting vapor comprises an injector having an orifice, the orifice being in the evaporation zone, at least one evaporation surface for evaporating feed and generating vapor, the evaporation surface being ...

07/21/05 - 20050158872 - Collider chamber apparatus and method of use of same
The disclosed apparatus includes a stator and a rotor disposed for rotation within the stator. An inner wall of the stator defines one or more collider chambers. Rotation of the rotor causes movement of fluid disposed between the rotor and stator and establishes a rotational flow pattern within the collider ...

07/14/05 - 20050153458 - Droplet formation systems for flow cytometers
A droplet forming flow cytometer system (1) allows high speed processing without the need for high oscillator drive powers through the inclusion of an oscillator or piezoelectric crystal (10) within the nozzle volume (3) and directly coupled to the sheath fluid. The nozzle container (27) continuously converges so as to ...

07/07/05 - 20050148095 - Method and apparatus for laser impulse sample deposition
A sample material, such as a liquid including genomic or proteomic materials, may be deposited on a work surface based on illumination of a sample transfer device by an illumination beam. Illumination of the sample transfer device may cause a portion of the sample transfer device to move and thereby ...

06/23/05 - 20050136548 - System and method for the analysis of bodily fluids
A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment ...

06/16/05 - 20050130318 - Bead dispensing system
A bead dispensing system is provided for delivering small amounts of substances onto substrates. The system can include, for example, a movable support structure having an array of spaced-apart projections depending from its lower side. An attraction source, such as a vacuum, magnetic, and/or electrostatic force, is operable at each ...



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