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Chemistry: Molecular Biology And Microbiology > Virus Or Bacteriophage, Except For Viral Vector Or Bacteriophage Vector; Composition Thereof; Preparation Or Purification Thereof; Production Of Viral Subunits; Media For Propagating Virus Or Bacteriophage, Except For Viral Vector Or Bacteriophage Vector; Composition Thereof; Preparation Or Purification Thereof; Production Of Viral Subunits; Media For PropagatingVirus Or Bacteriophage, Except For Viral Vector Or Bacteriophage Vector; Composition Thereof; Preparation Or Purification Thereof; Production Of Viral Subunits; Media For Propagating patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.04/12/07 - 20070082388 - Enhanced mediated dna transfer A method to increase the efficiency of transduction of hematopoietic and other cells by retroviruses includes infecting the cells in the presence of fibronectin or fibornectin fragments. The fibronectin and fibronectin fragments significantly enhance retroviral-mediated gene transfer into the cells, particularly hematopoietic cells including committed progenitors and primitive hematopoietic stem ... 03/29/07 - 20070072282 - Bovine adeno-associated viral (baav) vector and uses thereof The present invention provides a bovine adeno-associated virus (BAAV) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the BAAV vectors and particles. ... 01/11/07 - 20070010001 - Production of bacteriophage compositions for use in phage therapy The present invention relates to the use of bacteriophages to treat infections diseases. The invention provides a method for intermediate to large scale commercial production of bacteriophage composition, wherein the method reduces the production volume and elevates production yield. The invention further relates to improved bacteriophage compositions comprising specific sugars ... 12/28/06 - 20060292682 - Addition of transgenes into adenoviral vectors Adenoviral vectors are provided that contain a transgene inserted in the viral genome at a novel site such that one or more of native processing, regulatory signals or heterologous transcription signals such as branch point sites, splice acceptor sites, internal ribosome entry sites, self-processing cleavage sites and/or polyA signals contribute ... 11/30/06 - 20060270017 - Inactivation of a pathogen in a sample by a treatment with formalin and uv light The present invention relates to a method for inactivating virus in a sample by treating a virus containing sample with an effective concentration of formalin and by treating the sample with an effective dose of UV light in a flow-through apparatus. ... 11/30/06 - 20060270016 - Novel adenoviruses, nucleic acids that code for the same and the use of said viruses The present invention is related to an adenovirus expressing a first protein which is selected from the group comprising an E1B protein and an E4 protein, priorto a second protein which is selected from the group comprising an E1A protein. ... 11/02/06 - 20060246569 - Packaging systems for human recombinant adenovirus to be used in gene therapy Presented are ways to address the problem of replication-competent adenovirus in adenoviral production for use with, for example, gene therapy. Packaging cells having no overlapping sequences with a selected vector are suited for large scale production of recombinant adenoviruses. A described system produces replication-defective adenovirus. The system includes a primary ... 08/24/06 - 20060188977 - Non-tumorigenic mdck cell line for propagating viruses The present invention provides novel MDCK-derived adherent non-tumorigenic cell lines that can be grown in the presence or absence of serum. The cell lines of the present invention are useful for the production of vaccine material (e.g., viruses). More specifically, the cell lines of the present invention are useful for ... 07/27/06 - 20060166345 - Method of inactivating enveloped viruses in a viral preparation of non-enveloped viruses The present invention relates to a method of inactivating enveloped viruses in a viral preparation predominantly containing non-enveloped viruses by the action of a solvent at a temperature of between −5° C. and +50° C. and at a pH of between about 5 and 9. Its subject is also a ... 07/20/06 - 20060160202 - Artificial chromosomes comprising ehv sequences The invention belongs to the field of animal health, in particular equine diseases caused by equine herpesvirus (EHV). The invention relates to artificial chromosomes comprising the genome of equine herpesviruses, methods of producing attenuated or virulent EHV with or without the insertion of foreign genes, EHV obtainable with said methods ... 06/29/06 - 20060141602 - Packaging of positive-strand rna virus replicon particles The invention generally relates to recombinant polynucleotides, positive-strand RNA virus (psRNAV) recombinant expression vectors, and packaging systems. The packaging systems are based on the expression of helper functions by coinfecting re-combinant poxvirus vectors comprising recombinant polynucleotides. Methods for obtaining psRNAV replicon particles using these packaging systems are disclosed. Immunogenic compositions ... 05/04/06 - 20060094105 - Mixed cell diagnostic systems for detection of respiratory, herpes and enteric viruses The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of organisms to antimicrobial ... 05/04/06 - 20060094104 - Animal protein-free media for cultivation of cells The present invention relates to animal protein-free cell culture media comprising polyamines and a plant and/or yeast-derived hydrolysate. The invention also relates to animal protein-free culturing processes, wherein cells can be cultivated, propagated and passaged without adding supplementary animal proteins in the culture medium. These processes are useful in cultivating ... 03/23/06 - 20060063250 - Use of modified novirhabdoviruses to obtain vaccines The invention concerns the use of modified novirhabdoviruses wherein the NV protein gene is inactivated to obtain vaccines for use in particular in fish. ... 03/02/06 - 20060046291 - Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics The invention relates to virus like particles, their preparation and their use in pharmaceutical screening and functional genomics. The invention further provides a variety of assay formats to be used with said virus like particles. ... 02/09/06 - 20060030020 - Lambdoid bacteriophage vectors for expression of foreign proteins Lambdoid phage comprising a matrix of proteins encapsulating a genome encoding first and second polypeptides of an autogenously assembling receptor and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a lambdoid phage tail protein matrix anchor domain fused to at least one of the ... 01/26/06 - 20060019369 - Recombinant vector containing infectious human cytomegalovirus genome with preserved wild-type characteristics of clinical isolates A recombinant vector containing infectious genome of human cytomegalovirus (HCMV) and being useful for the production of reconstituted HCMV virus retaining phenotypic characteristics of a clinical virus isolate including the ability to grow on endothelial cells and to induce microfusion is characterized in that it is obtainable by inserting DNA ... 12/22/05 - 20050282263 - Flexible vaccine assembly and vaccine delivery platform Herein described are various methods for making a vaccine that are made of re-assembled virus like particles (VLP). First, the VLPs are disassembled into coat proteins or encapsidation intermediate populations. Each population undergoes, for instance, chemical conjugation of unique peptide or nucleic moieties to form separate populations. Thereafter, a predetermined ... 12/01/05 - 20050266544 - Methods and compositions for increasing viral vector production in packaging cell lines Methods and compositions are disclosed to increase viral titer of vector producing cell lines and to reduce potential for re-infection by inhibiting deactivation of helper virus. According to the invention, methylation of helper virus and concomitant helper virus inactivation is directly correlated with increased super-infection and decreased vector production. Novel ... 11/24/05 - 20050260734 - Packaging cells The invention described herein allows the production of recombinant retroviruses (retroviral vector particles) from producer cells which are safer and of higher titer than normal. In addition, methods are provided for making helper cells which, when a recombinant retrovirus genome is introduced to make a producer line, produce particles that ... 10/27/05 - 20050239188 - Virus envelope vector for gene transfer A gene transfer vector is prepared by introducing an exogenous gene into an inactivated virus envelope, through a freezing and thawing treatment or mixing with a detergent. There are also provided a pharmaceutical composition for gene therapy containing this gene transfer vector, a kit containing this gene transfer vector, and ... 10/27/05 - 20050239187 - Methods to culture circovirus The present invention relates to methods for culturing circovirus and in particular, porcine circovirus. The present invention provides compositions and methods for culturing porcine circovirus in mammalian cells expressing mammalian adenovirus E1 function. ... 09/29/05 - 20050214923 - Pan cancer oncolytic vectors and methods of use thereof Replication-competent adenoviral vectors which selectively replicate in cancer cells are provided. The replication-competent viral vectors comprise an E2F responsive promoter and/or a telomerase promoter operatively linked to an adenoviral coding region. The replication-competent adenoviral vectors effectively replicate in a variety of types of cancer cells and find broad utility in ... 09/15/05 - 20050202553 - Animal cells and processes for the replication of influenza viruses Animal cells are described which can be infected by influenza viruses and which are adapted to growth in suspension in serum-free medium. Processes for the replication of influenza viruses in cell culture using these cells are furthermore described, as well as vaccines which contain the influenza viruses obtainable by the ... 09/01/05 - 20050191740 - Cell-specific retroviral vectors with antibody domains and method for the production thereof for selective gene transfer The invention relates to cell-specific retroviral vectors with antibody recognition domains (scFv), which are suitable for cell-specific transduction of a selected mammal cell type (cell targeting), to methods for the production of the cell-specific retroviral vectors and to the use thereof in gene transfers into selected cells. The invention further ... 08/18/05 - 20050181495 - Large scale productions of virus antigen The present invention provides improved methods of production of viral antigen on a culture of adherent cells bound to a microcarrier, wherein the methods provide for increased viral antigen yield per culture medium volume. The invention is also directed to a cell culture biomass of adherent cells having increased cell ... 08/18/05 - 20050181494 - Novel lambda phage display system and the process The present invention relates to a process of obtaining recombinant lambdoid bacteriophage with high density display of functional peptides and proteins on surface of said phage comprising of: constructing a donor plasmid having a nucleotide sequence that defines the elements for replication of the vector in bacteria, a selectable marker, ... 08/11/05 - 20050176130 - Functional mutations in respiratory syncytial virus The present invention provides recombinant respiratory syncytial viruses that have an attenuated phenotype and that comprise one or more mutations in the viral P, M2-1 and/or M2-2 proteins, as well as live attenuated vaccines comprising such viruses and nucleic acids encoding such viruses. Recombinant RSV P, M2-1 and M2-2 proteins ... 08/11/05 - 20050176129 - Adenovirus vector This invention relates to an adenovirus vector having excellent gene transfection activity on specific cell lines, particularly on hematopoietic cells. This adenovirus vector derives from the adenovirus type 35 genome by at least partial or total deletion of the E1 region therefrom. The adenovirus vector according to this invention has ... 08/11/05 - 20050176128 - Method for assembling subunits into capsoids The invention relates to a method for assembling subunits forming capsoides in a solution containing a reduction agent in order to obtain capsoides. Initially, the reduction agent is inactivated or removed from the solution, subsequently, the ionic strength in the solution is increased to such an extent by adding at ... 07/14/05 - 20050153419 - Methods for producing cell lines stable in serum-free medium suspension culture The present invention provides methods for adapting cells, such as A549 cells, to growth in serum-free and animal material-free medium suspension culture. The present invention provides methods for preparing viruses, such as adenovirus, from the A549 cells adapted for growth in serum-free and animal material-free medium in suspension culture. ... 06/02/05 - 20050118700 - Immortalized avian cell lines The invention features non-transformant immortal avian cells, in particular derived from avian tissues, i.e., other than blood or hematopoietic cells, particularly fibroblasts and epithelial cells, for instance of embryos. The avian cells are immortalized by the SV40 T+t gene in the dependence of the MTI promoter. In particular they integrate ... 06/02/05 - 20050118699 - Packaging complementation cell-line for sv-40 vectors The present invention relates to a complementation SV40 packaging cell line for in-trans complementation of viral T-antigen (T-Ag). This cell line eliminates the generation of viable virus carrying the T-Ag gene, by reducing homologous recombination in packaging process of an SV40 vector, wherein said cell line is transformed with at ... 06/02/05 - 20050118698 - Multiplication of viruses in a cell culture The present invention concerns methods for multiplication of viruses in cell culture in which cells are infected with a virus and after infection the cells are cultured in cell culture under conditions that permit multiplication of the viruses and at the same time targeted additional, at least two-fold, multiplication of ... ### FreshPatents.com Support |