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Lactic Acid

Lactic Acid patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

Related Categories:

Chemistry: Molecular Biology And Microbiology


Micro-organism, Tissue Cell Culture Or Enzyme Using Process To Synthesize A Desired Chemical Compound Or Composition > Preparing Oxygen-containing Organic Compound > Containing A Carboxyl Group > Lactic Acid



Fermentation of waste gases
12/18/14 - 20140370559 - The invention relates to the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the microbial fermentation of a gaseous substrate derived from the conversion of a biogas stream. The invention relates to the conversion of a biogas stream comprising methane to a gaseous...

Methods for producing high levels of carboxylic acids by lignocellulosic biomass processing
12/11/14 - 20140363861 - The technology relates, in certain aspects, to the use of novel extreme thermophile microorganisms, which are able to convert lignocellulosic biomass to carboxylic acids, in particular to lactic acid and/or acetic acid, salts or esters thereof....

Method of producing chemical substance
11/27/14 - 20140349354 - A method produces a chemical product by continuous fermentation including filtering a culture liquid of a microorganism(s) through a separation membrane, retaining unfiltered liquid in, or refluxing unfiltered liquid to, the culture liquid, adding a fermentation feedstock to the culture liquid, and recovering a product in the filtrate, wherein the...

Yeast strain for lactic acid production by using pentose and hexose
11/20/14 - 20140342415 - The present invention provides a biologically pure culture of Saccharomyces cerevisiae, which culture has a characteristic nature capable of highly producing lactic acid. A method for preparing the biologically pure culture and a method for production of lactic acid are also provided....

Lactic acid extraction
11/13/14 - 20140335581 - A method for recovering lactic acid from an aqueous mixture including the steps of: providing an aqueous mixture including lactic acid and at least 5 wt. % dissolved magnesium chloride, based on the total weight of water and dissolved material in the aqueous mixture; extracting the lactic acid from the...

Method for producing lactic acid
10/30/14 - 20140322773 - A method for producing lactic acid, which comprises subjecting glucose to lactic acid fermentation by using a fission yeast having a lactic acid fermentation ability and recovering lactic acid produced thereby, characterized in that a fermentation liquor created from an aqueous glucose solution by lactic acid fermentation is replaced with...

Fermentation of glycerol to organic acids
08/21/14 - 20140234923 - The present invention is in the field of producing organic acids and other useful chemicals via biological fermentation using glycerol as a source of carbon. Novel microorganisms and fermentation processes are described that are capable of converting glycerol to useful organic acids in high yield and high purity....

Variants of glycerol dehydrogenase having d-lactate dehydrogenase activity and uses thereof
08/21/14 - 20140234924 - The present invention provides methods of designing and generating glycerol dehydrogenase (GlyDH) variants that have altered function as compared to a parent polypeptide. The present invention further provides nucleic acids encoding GlyDH polypeptide variants having altered function as compared to the parent polypeptide. Host cells comprising polynucleotides encoding GlyDH variants...

Method for enhancing the fermentative potential and growth rate of microorganisms under anaerobiosis
08/14/14 - 20140227749 - The present invention concerns a method for enhancing the growth rate, the biomass production and/or the fermentative potential of an anaerobic microorganism, comprising the steps consisting in: (a) modifying said anaerobic microorganism by inactivating the ohrR gene, the ohrR gene product or homolog thereof; (b) culturing the modified anaerobic microorganism...

Microorganism over-expressing lactic acid transporter gene and having inhibitory pathway of lactic acid degradation, and method of producing lactic acid using the microorganism
08/07/14 - 20140220647 - A recombinant microorganism comprising a lactic acid (LA) transporter, wherein the expression of the LA transporter in the recombinant microorganism is increased relative to a parent microorganism, and a method of producing lactic acid using same....

System and method for improved gas dissolution
07/31/14 - 20140212937 - The invention provides a microbubble generation system with increased efficiency and flexibility compared to known systems. Further, the invention provides a method of microbubble generation. In particular, invention relates to increasing the efficiency of a fermentation reaction by reducing bubble size and increasing gas absorption into a liquid fermentation broth....

Microorganism and method for lactic acid production
06/19/14 - 20140170719 - The present invention relates generally to compositions and methods for producing lactic acid using a lactic acid producing microorganism. More specifically, the present invention relates to methods for producing lactic acid with high yield, high concentration and high volumetric productivity through biological fermentation by Enterococcus faecalis, or recombinant microorganisms transformed...

Processes for producing low-ash biomass for combustion or pellets
06/05/14 - 20140154759 - This invention provides processes and apparatus to convert biomass, including wood and agricultural residues, into low-ash biomass pellets for combustion, alone or in combination with another solid fuel. Some embodiments provide processes for producing low-ash biomass from cellulosic biomass, comprising providing an aqueous extraction solution with acetic acid; extracting the...

Acidogenic clostridia and processes of using thereof for producing volatile fatty acids
05/01/14 - 20140120591 - An isolated biologically pure culture of Clostridium tyrobutyricum ITRI04001 or an isolated biologically pure culture of Clostridium tyrobutyricum having the genotypic characteristics of ITRI04001 useful for syngas fermentation. Volatile free acids are produced by a method comprising culturing a microorganism having the genotypic characteristics of ITRI04001 in a medium; providing...

Bioconversion processes using water-insoluble liquids
04/17/14 - 20140106420 - Processes are disclosed for bioconversion processes in which a ME biocatalyst is surrounded by water-insoluble liquid during the bioconversion to facilitate one or more of mass transfer of substrate to and bioproduct from the biocatalyst and the separation and recovery of bioproduct from the water-insoluble liquid. The ME biocatalyst irreversibly...

Biofilm photobioreactor system and method of use
04/03/14 - 20140093924 - Flat panel biofilm photobioreactor systems with a photosynthetic, autofermentative microorganism that forms a biofilm and methods for using the same to make metabolic intermediate compound(s) through photosynthesis and to convert metabolic intermediate compound(s) into chemical product(s) such as a biofuel or a feedstock through autofermentation....

Novel microbial biocatalysts that enables use of cellodextrin as biofuel
03/27/14 - 20140087435 - The present disclosure provides genetically engineered biocatalysts which enable intracellular assimilation of cellodextrin. The genetically engineered biocatalyst co-expresses a cellodextrin phosphorylase (CDP) gene and a cellobiose phosphorylase (CBP) gene. Further, the genetically engineered biocatalyst includes a first synthetic promoter used to express the cellodextrin phosphorylase (CDP) gene and a second...

Mutant strain of lactic acid producing yeast and process for producing lactic acid
02/20/14 - 20140051138 - A lactic acid-producing yeast mutant which is a mutant of a yeast prepared by introduction of a lactate dehydrogenase gene that results in lactic acid-producing ability, the mutant having, in a medium at pH 3, a lactic acid-producing ability equivalent to or higher than the lactic acid-producing ability of a...

Genetic modification of homolactic thermophilic bacilli
01/16/14 - 20140017745 - Disclosed herein is a genetic modification of moderately thermophilic Bacillus species that are facultative anaerobic and homolactic. The method includes introducing DNA cloned in a thermosensitive plasmid system containing a pSH71 replicon or a homologue thereof into cells of a moderately thermophilic Bacillus species that is facultative anaerobic and homolactic;...

Method of producing lactic acid by continuous fermentation
01/16/14 - 20140017746 - A method of producing lactic acid by continuous fermentation includes filtering a culture of polyploidy prototrophic yeast having a capacity to produce lactic acid by introduction of a lactate dehydrogenase gene through a porous membrane having an average pore size of not less than 0.01 μm and less than 1...

Enhanced efficiency ethanol and sugar conversion processes
12/19/13 - 20130337517 - Overlay processes are disclosed for making ethanol that not only increase ethanol conversion but do so in a cost effective manner with a reduction in energy requirements per unit of ethanol production. The processes can provide, if desired, higher organic compound as a co-product with ethanol....

Method for producing chemicals by continuous fermentation
12/12/13 - 20130330792 - A method of producing a chemical by continuous fermentation includes a fermentation step of converting a fermentation feedstock to a fermentation liquid containing a chemical by fermentation on cultivation of a microorganism; a membrane separation step of recovering the chemical as a filtrate by a separation membrane from the fermentation...

Production method for chemicals by continuous fermentation
12/05/13 - 20130323805 - A method of producing chemicals through continuous fermentation includes washing a membrane with a washing liquid supplied from a permeate side of a membrane unit in a continuous fermentation; filtering a culture medium containing a fermentation feedstock, a chemical and a microbe or a cultured cell through a separation membrane;...

Use of monascus in organic acid production
10/31/13 - 20130288319 - The present invention provides tools and methods for producing organic acids using strains of Monascus which are tolerant to high organic acid concentrations at low pH....

Method for producing chemical by continuous fermentation
10/24/13 - 20130280773 - A method of producing a chemical includes a fermentation step that converts a fermentation feedstock, through fermentation by culturing a microorganism or culture cells, into a fermented liquid containing the chemical, and a membrane separation step that collects the chemical, as a filtrate, from the fermented liquid with the use...

Method for producing d-type lactic acid
10/10/13 - 20130266995 - The present invention provides a method for producing D-type lactic acid, by a sugar fermentation of sugar. In accordance with the method of the invention, lactic acid produced during the fermentation reaction is selectively absorbed and detached using an active carbon stick. The method does not require steps, such as,...

Method and apparatus for producing lactic acid
10/10/13 - 20130266996 - The present invention provides an apparatus and a method for producing lactic acid, wherein only lactic acid is selectively absorbed and separated from fermentation liquor using a lactic acid absorption resin and wherein a neutralizing agent is not used. The present invention does not include a neutralizing process and a...

Process for producing bio-based product from straw hemicellulose and fully utilizing the components thereof
09/26/13 - 20130252293 - Provided is a process for producing biomass-based product from straw hemicellulose and utilizing the components thereof thoroughly. Steam-explosion and acid-hydrolysis are combined in the pre-treatment of straw in the process, thus a higher concentration of a sugar liquid can be obtained, and furfural and acetic acid can be recovered. The...

Novel lactic acid bacterium and method for producing l-lactic acid using same
07/04/13 - 20130171705 - L-Lactic acid fermentation using non-edible biomass requires a lactic acid bacterium suitable for fermentation using a mixture comprising oligosaccharides or mixed saccharides produced by enzymatic treatment of cellulose and hemicellulose, so that simultaneous saccharification and fermentation are enabled. Further, it must be taken into consideration that use of pentoses such...

System and process for correcting constant volume acidity of fermentative media for producing organic acids
06/20/13 - 20130157329 - A system (100, 200) is described for correcting constant volume acidity of fermentative media for the production of organic acids, which comprises a fermenter (1) provided with a pH sensor (P1) a filtration module (2) provided with a filtering element, an addition vessel (3) provided with a main metering element...

Bacillus coagulans strains and their applications in l-lactic acid production
06/06/13 - 20130143286 - The invention is concerned with the strains of B. coagulans for lactic acid production and the related methods, in which the carbon sources are pentose or hexose or the agricultural or industrial wastes containing pentose or hexose or a mixture of both. According to the invention, the highest amount of...

Process for the conversion of biomass of plant origen, and a combustion process
06/06/13 - 20130143287 - The invention provides a process for the conversion of biomass into a biomass product which is suitable for use as a fuel. The biomass is of plant origin and comprises microorganisms naturally occurring in the biomass. The process comprises—preparing a slurry by dispersing the biomass comprising the naturally occurring microorganisms...

Acid production by fermentation
05/02/13 - 20130109066 - The invention provides methods for producing Lactate by anaerobic Fermentation. According to particular methods of the invention, Lactate is produced by anaerobic fermentation of a substrate comprising hydrogen and carbon monoxide....

Xylose isomerase and use thereof
04/18/13 - 20130095538 - It is an object of the disclosure of the present description to provide an eukaryotic cell having xylose utilization ability. The disclosure of the present description provides a novel eukaryotic cell having xylose utilization ability by transforming a yeast or other eukaryotic cell using DNA that codes a xylose isomerase...

Lactic acid production method
04/18/13 - 20130095539 - A method of producing lactic acid by separating lactic acid produced in a culture solution by microbial fermentation, comprising: a step (A) of filtering the culture solution through a nano-filtration membrane; and a step (B) of distilling a lactic-acid-containing solution produced in step (A) under a pressure of 1 Pa...

L-lactate production in cyanobacteria
03/21/13 - 20130071895 - A process of producing L-lactate as defined herein by feeding carbon dioxide to a culture of a cyanobacterial cell and subjecting said culture to light, wherein said cell is capable of expressing a nucleic acid molecule, wherein the expression of said nucleic acid molecule confer on the cell the ability...

Manufacturing process of purified lactic acid
02/28/13 - 20130052703 - A manufacturing process of purified lactic acid includes a fermentation process where a pH adjusting agent containing calcium and a microorganism are added to a sugar-containing solution to produce lactic acid in the form of calcium lactate, and a purification process where sulfuric acid is added to a solution containing...

Processing biomass
02/28/13 - 20130052704 - Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed for use in the production of useful products, such as fuels. For example, systems can use biomass materials, such as cellulosic and/or lignocellulosic materials, to enhance the production of a product, e.g., the production of ethanol and/or butanol...

Fermentation of waste gases
02/21/13 - 20130045517 - The invention relates to the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the microbial fermentation of a gaseous substrate derived from the conversion of a biogas stream. The invention relates to the conversion of a biogas stream comprising methane to a gaseous...

Method for producing d type lactic acid with high optical purity
01/31/13 - 20130029389 - The present invention provides a method for producing D-type lactic acid by using E. coli and glucose derived from a plant as active ingredient, in which D-type lactic acid is a raw material of D-type polylactic acid in order to produce a stereo-complex polylactic acid blend which is a valuable...

Thermophilic thermoanaerobacter italicus subsp. marato having high alcohol productivity
12/06/12 - 20120309065 - Strict anaerobic thermophilic bacterium belonging to the group of Thermoanaerobacter italicus subsp. marato subsp. nov. and mutants and derivatives thereof. The bacterium is particularly suitable for the production of fermentation products such as ethanol, lactic acid, acetic acid and hydrogen from lignocellulosic biomass....

Hollow fiber membrane module for use in production of chemical substance, and process for production of chemical substance
10/25/12 - 20120270286 - A hollow fiber membrane module for use in production of a chemical substance, which is used in continuous fermentation including filtering a fermentation broth of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation...

Cellulose and xylan fermentation by novel anaerobic thermophilic clostridia isolated from self-heated biocompost
10/18/12 - 20120264183 - A new species of an anaerobic thermophilic cellulolytic and xylano lytic bacterium is disclosed. One particular strain of this new species has been deposited with the ATCC under Deposit No. PTA-10114. It is also provided a method for isolating, culturing and utilizing this novel bacterium for the conversion of biomass...

Fermentation process at reduced pressure
09/27/12 - 20120244587 - A fermentation process includes contacting a carbohydrate source with a microorganism in an aqueous fermentation broth to form a fermentation product which is a salt or a product with a boiling point above the boiling point of water. The fermentation process is carried out at a pressure which is below...

Transformant and process for production thereof, and process for production of lactic acid
08/23/12 - 20120214214 - The present invention relates to a transformant, containing a lactate dehydrogenase gene which is introduced into Schizosaccharomyces pombe as a host, in which a part of a gene cluster encoding a pyruvate decarboxylase in the Schizosaccharomyces pombe host is deleted or inactivated....

Fermentation of moderately thermophilic bacilli on sucrose
08/16/12 - 20120208248 - A method for the construction of a moderately thermophilic Bacillus strain capable of utilising sucrose as a carbon source includes the transformation of a parent moderately thermophilic Bacillus strain not capable of utilising sucrose as a carbon source with a polynucleotide comprising a DNA sequence that encodes a polypeptide having...

Methods and compositions for improving the production of products in microorganisms
08/02/12 - 20120196338 - Methods and compositions are provided for improving the production of products, such as fuel products like ethanol, in microorganisms. In particular, methods and compositions are described for improving ethanol production utilizing genes identified in Clostridium phytofermentans....

Engineering of thermotolerant bacillus coagulans for production of d(-)-lactic acid
05/24/12 - 20120129231 - Genetically modified microorganisms having the ability to produce D(−)-lactic acid at temperatures between 30° C. and 55° C. are provided. In various embodiments, the microorganisms may have the chromosomal lactate dehydrogenase (ldh) gene and/or the chromosomal acetolactate synthase (alsS) gene inactivated. Exemplary microorganisms for use in the disclosed methods are...

Mutant methylglyoxal synthase (mgs) for the production of a biochemical by fermentation
05/17/12 - 20120122166 - the methylglyoxal synthase activity of the mutant MGS is not inhibited by orthophosphate as compared to the parent enzyme....

Method for producing lactic acid
05/17/12 - 20120122167 - Provided is a method for producing lactic acid, which includes: obtaining D-lactic acid or L-lactic acid by carrying out lactic acid fermentation using a lactic acid-producing microorganism under a pressurized condition that exceeds normal pressure and is capable of maintaining lactic acid production activity of the lactic acid-producing microorganism....

Gene knockout mesophilic and thermophilic organisms, and methods of use thereof
04/19/12 - 20120094343 - One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt...

Polypeptide having d-lactate dehydrogenase activity, polynucleotide encoding the polypeptide, and process for production of d-lactic acid
03/22/12 - 20120070871 - Highly productive D-lactic acid fermentation uses a transformant obtained by introducing into a host cell a polynucleotide encoding a polypeptide according to any one of the following (A) to (C) in such a manner that the polypeptide is expressed, which polypeptide has a D-lactate dehydrogenase activity higher than those of...

Homolactic fermentation from pentose
03/08/12 - 20120058528 - Provided is a lactic acid bacterium capable of homolactic fermentation using a pentose as a substrate, the lactic acid bacterium utilizing a pentose, and in which a phosphoketolase pathway is blocked and a pentose phosphate pathway is activated. Also provided is a method for producing lactic acid from a pentose...

Method for highly efficient production of lactic acid using candida utilis
03/08/12 - 20120058529 - There is disclosed a yeast strain of Candida utilis, wherein the yeast strain has been transformed with at least one copy of a gene that is operatively linked to a promoter sequence enabling expression of the gene and encodes a polypeptide having activity of lactate dehydrogenase. The yeast strain is...

High performance metabolic bacteria
03/01/12 - 20120052540 - The present invention relates to novel stress-resistant bacteria and the uses thereof. More specifically, the invention relates to isolated stress-resistant bacteria having advantageous properties for the production of organic acids or alcohols in various culture conditions. The invention also relates to methods of producing organic acids or alcohols using said...

Method for production of substance in candida utilis using xylose as carbon source
02/23/12 - 20120045803 - Disclosed is a yeast strain of Candida utilis, wherein the yeast strain has been transformed with at least one of three genes that are operatively linked to a promoter sequence and encode polypeptides having activities of xylose reductase, xylitol dehydrogenase, and xylulose kinase. The yeast strain is useful for producing...

Acid production by fermentation
02/16/12 - 20120040421 - The invention provides methods for producing Lactate by anaerobic Fermentation. According to particular methods of the invention, Lactate is produced by anaerobic fermentation of a substrate comprising hydrogen and carbon monoxide....

Method for producing d-lactic acid, and method for increasing optical purity of d-lactic acid or yield of d-lactic acid relative to sugar in lactic acid
12/29/11 - 20110318794 - Disclosed is a method for producing D-lactic acid by allowing a microorganism to utilize a purified treacle and culturing the microorganism. Also disclosed is a method for increasing the optical purity of D-lactic acid in lactic acid. Specifically disclosed is a method for producing D-lactic acid by allowing a microorganism...

Manufacturing method of optically active d type lactic acid using byproducts prepared from rice polishing process
10/20/11 - 20110256596 - Disclosed is a method for manufacturing D type lactic acid wherein byproducts (e.g., rice bran and pulverized rice) obtained during a rice polishing process are saccharified by using α-amylase and amyloglucosidase and then fermented by a microorganism, Sporolactobacillus inulinus. According to the method, byproducts generated during a rice polishing process...

Light-driven co2 reduction to organic compounds to serve as fuels or as industrial half products by an autotroph containing a fermentative gene cassette
09/01/11 - 20110212498 - A process of producing an organic compound and/or an intermediary compound as defined herein by feeding carbon dioxide to a culture of a cyanobacterial cell and subjecting the culture to light, wherein the cell is capable of expressing a nucleic acid molecule, wherein the expression of the nucleic acid molecule...

Production of lactic acid from hemicellulose extracts
07/28/11 - 20110183389 - A method is provided for producing lactic acid comprising fermenting sugars derived from biomass using sugar consuming bacteria to produce lactic acid. In certain embodiments, the biomass is woody biomass, and the bacteria are pentose consuming bacteria such as Bacillus coagulans....

Bacterium capable of producing lactic acid, and method for producing lactic acid
07/14/11 - 20110171703 - The present invention provides: a lactic acid-producing Escherichia coli including an enzymatic activity of at least one NAD-dependent lactate dehydrogenase and an enzymatic activity of at least one NAD-independent lactate oxidoreductase, both of which are enhanced so as to decompose one of D-lactic acid or L-lactic acid and to produce...

Method for producing lactic acid from plant-derived raw material, and lactic-acid-producing bacterium
07/14/11 - 20110171704 - The present invention provides: a lactic acid-producing Escherichia coli comprising at least one gene of a sucrose non-PTS gene group, including at least a sucrose hydrolase gene, provided that a combination of a repressor protein (cscR), a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) and a...

Process for producing organic acid
06/23/11 - 20110151528 - This invention is intended to improve the efficiency of organic acid fermentation in a simple manner without mutant breeding, DNA recombination breeding, or other means, when producing an organic acid via fermentation with the use of yeast that produces the organic acid of interest. The efficiency of the yeast's ability...

Microorganism for the production of succinic acid
06/02/11 - 20110129885 - The invention relates to an isolated genetically modified microorganism in which the gene IDH1 and at least one of the genes SDH2 and DIC1 are under the control of a first promoter that is repressed to a growth culture medium by means of a cultivation additive and is active in...

Improved yeast strains for organic acid production
05/05/11 - 20110104769 - The present invention relates to the production of organic acids with yeasts that overexpress at least one sugar transporter. The yeast might express further genes related to the production of the desired organic acid. The organic acid is produced by cultivation of the yeast overexpressing a sugar transporter in an...

Method of producing lactic acid by continuous fermentation
03/03/11 - 20110053231 - A method of producing lactic acid continuous fermentation including filtering a culture of polyploid yeast having a capacity to produce lactic acid through a porous membrane having an average pore size of not less than 0.01 μm and less than 1 μm, and recovering the product from the filtrate while...

Yeast mutant and substance production method using the same
02/17/11 - 20110039316 - Preferably a yeast mutant is a mutant strain having lowered alcohol productivity than that of a wild-type strain....

Polypeptide having glyoxalase iii activity, polynucleotide encoding the same and uses thereof
01/20/11 - 20110014666 - The invention also relates to the production of commodity chemicals, especially 1,2-propanediol, acetol, and lactic acid by fermenting microorganisms wherein their glyoxalase III activity is modulated....

Production of lactic acid by way of fermentation and extraction of amines
10/28/10 - 20100273224 - The invention relates to a process for the production and isolation of lactic acid which is produced by way of fermentation of a carbohydrate-bearing feedstock and the addition of ammonia. The lactic acid is released from the ammonium salt of the lactate by adding a mineral acid and the lactic...

Expression cassette for lactase dehydrogenase, transformed yeast and method of producing lactic acid
10/28/10 - 20100273225 - A gene expressing cassette codes lactate dehydrogenase that is needed for prevention of deterioration in lactic acid yield and lactic acid production rate in continuous culture with simultaneous filtration of a yeast strain having a lactic acid-producing ability, which achieves high optical purity, high lactic acid yield and high lactic...