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Chemistry: Molecular Biology And Microbiology > Micro-organism, Tissue Cell Culture Or Enzyme Using Process To Synthesize A Desired Chemical Compound Or Composition > Preparing Alpha Or Beta Amino Acid Or Substituted Amino Acid Or Salts Thereof

Preparing Alpha Or Beta Amino Acid Or Substituted Amino Acid Or Salts Thereof

Preparing Alpha Or Beta Amino Acid Or Substituted Amino Acid Or Salts Thereof patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

04/12/07 - 20070082383 - Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production
Isolated nucleic acid molecules, designated SMP nucleic acid molecules, which encode novel SMP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SMP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

03/15/07 - 20070059810 - Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins
Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

03/15/07 - 20070059809 - Corynebacterium glutamicum genes encoding regulatory proteins
Isolated nucleic acid molecules, designated MR nucleic acid molecules, which encode novel MR proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MR nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

02/22/07 - 20070042474 - Corynebacterium glutamicum genes encoding novel proteins
Isolated nucleic acid molecules, designated MCP nucleic acid molecules, which encode novel MCP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

02/01/07 - 20070026505 - Amino acid and metabolite biosynthesis
Bacterial strains that are engineered to increase the production of amino acids, including aspartate-derived amino acids (e.g., methionine, lysine, threonine, isoleucine, and S-adenosylmethionine (S-AM)) and cysteine, and related metabolites are described. The strains can be genetically engineered to harbor one or more nucleic acid molecules (e.g., recombinant nucleic acid molecules) ...

01/18/07 - 20070015261 - Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals
The invention provides microbial strains possessing improved properties for production of aspartate-derived amino acids and chemicals. Methods of making such strains are provided. These methods include altering expression of the aceBAK operon, the glcB gene, or both. Alteration of expression may be accomplished through increased transcription, relief from native transcriptional ...

01/04/07 - 20070004014 - Method for producing l-threonine
A method for producing L-threonine is described which includes the steps of culturing a microorganism belonging to the genus Escherichia that has an ability to produce L-threonine, in a fermentation medium containing a carbon source, a nitrogen source, and a sulfur source, and collecting L-threonine, wherein the sulfur concentration in ...

12/28/06 - 20060292674 - Corynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

12/21/06 - 20060286644 - Process for preparing l-amino acids using improved strains of the enterobacteriaceae family
The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family, characterized in that a) the desired L-amino acid-producing microorganisms, in which the ytfQ-ORF, or nucleotide sequences or alleles encoding the gene product, is/are enhanced, in particular overexpressed, is cultured in a medium ...

12/21/06 - 20060286643 - Method for producing l-amino acid using bacterium of enterobacteriaceae family having expression of yafa gene attenuated
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the yafA gene. ...

11/23/06 - 20060263861 - Method for producing beta-hydroxy amino acid and enzyme used therefor
A method for producing β-hydroxy amino acid and its optically-active isomer is provided. The β-hydroxy amino acid is produced by reacting a predetermined D-α-amino acid and 5,10-methylene tetrahydrofolic acid in the presence of an enzyme derived from a microorganism belonging to the genera Paracoccus, Aminobacter, or Ensifer. ...

11/16/06 - 20060257980 - Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
wherein R1 to R9, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ...

11/16/06 - 20060257979 - Process for preparing l-amino acids using improved strains of the enterobacteriaceae family
The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family, characterized in that a) the desired L-amino acid-producing microorganisms, in which the yjcG-ORF, or nucleotide sequences or alleles encoding the gene product, is/are enhanced, in particular overexpressed, is cultured in a medium ...

11/16/06 - 20060257978 - Deracemisation of amines
The present invention relates to a method for the deracemisation or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. The invention also provides a method for selecting a suitable ...

11/09/06 - 20060252134 - Enantioselective oligomerization of alpha-hydroxy carboxylic acids and alpha-amino acids
An enzymatic synthesis and composition of oligomers and co-oligomers comprised of α-hydroxy carboxylic acids and α-amino acids or peptides is disclosed. In a preferred embodiment, a α-hydroxy carboxylic acid with a specific chiral configuration is linked by an amide linkage to a α-amino acid specific with a specific chiral configuration ...

11/09/06 - 20060252133 - Process for the preparation of l-threonine
The invention relates to an improved process for the fermentative preparation of L-threonine using bacteria of the Enterobacteriaceae family which produce L-threonine. ...

11/02/06 - 20060246552 - Novel plasmid autonomously replicable in enterobacteriaceae family
A gene isolated from a microorganism selected from the group consisting of Pantoea bacteria, Erwinia bacteria, and Enterobacter bacteria, and encoding a Rep protein or a homologue thereof is described. A plasmid containing the gene which is autonomously replicable in Enterobacteriaceae bacteria is also described. A Enterobacteriaceae microorganism containing the ...

10/26/06 - 20060240532 - Dna encoding hydantoinase, dna encoding n-carbamyl-l-amino acid hydrolase, recombinant dna, transformed cell, method of producing protein and method of producing optically active amino acid
The present invention provides a method of producing optically active amino acids from 5-substituted hydantoin by isolating a hydantoinase gene and an N-carbamyl-L-amino acid hydrolase gene involved in an ability to convert 5-substituted hydantoin or N-carbamylamino acid into optically active amino acids from a microorganism of the genus Microbacterium having ...

10/19/06 - 20060234357 - Novel polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
The present invention provides novel polypeptides and polynucleotides useful as biotechnological tools, specifically identified in a coryneform bacterium Corynebacterium glutamicum ssp. lactofermentum and methods of producing substances in organisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

10/19/06 - 20060234356 - Novel polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
The present invention provides novel polypeptides and polynucleotides useful as biotechnological tools, specifically identified in a coryneform bacterium Corynebacterium glutamicum ssp. lactofermentum and methods of producing substances in organisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

10/12/06 - 20060228787 - Mutants for the preparation of d-amino acids
The present invention relates to specific E. coli mutants which can be used for the synthesis of D-amino acids, and to such a process. The mutants are distinguished by deficiencies in particular enzymes which break down D-amino acids. ...

09/28/06 - 20060216796 - Method for producing l-amino acid by fermentation
L-threonine or L-isoleucine is produced by culturing a bacterium which belongs to the genus Escherichia and has an ability to produce L-threonine or L-isoleucine, and wherein expression of a threonine operon is directed by its native promoter, and from which at least a leader sequence and an attenuator are deleted, ...

09/21/06 - 20060211097 - Process for producing enantiopure beta-amino acid derivatives, and enantiopure beta-amino acid derivatives
Process for producing enantiopure β-amino acid derivatives corresponding to general formula (I) R1-NZ-CHR2—CH2—COOR3 (I) in which R1 and R2 independently denote organic residues optionally forming a cyclic substituent, R3 denotes H or an organic residue, and Z represents H or an amino function-protecting group, comprising a step in which a ...

09/14/06 - 20060205045 - Novel dehydrogenase and a gene encodign the same
The object of the present invention is to provide a novel dehydrogenase having a property which is different from that of known dehydrogenases. The present invention provides a dehydrogenase having the following physicochemical properties: (1) effect: to produce N-alkyl-L-alanine from pyruvic acid and alkylamine or dialkylamine using NADPH and/or NADH ...

09/14/06 - 20060205044 - Escherichia coli strains that over-produce l-threonine and processes for their production
The invention relates to novel bacterial strains and constructs as well as methods for production of L-amino acids, including but not limited to L-threonine. Such novel bacterial strains may be characterized by, for instance, Escherichia coli strains in which an aspartate semialdehyde dehydrogenase (asd) gene is operably associated with at ...

09/14/06 - 20060205043 - Method for producing target substance by fermentation
A method for producing a target substance by utilizing a microorganism by culturing the microorganism in a medium to produce and accumulate the target substance in the medium and collecting the target substance from the culture is described. The microorganism is a mutant recombinant strain in which maltose assimilation is ...

08/10/06 - 20060177912 - Nucleotide sequences which code for the dep34 gene
The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the dep34 gene, and a host-vector system having a coryneform host bacterium in which the dep34 gene is present in attenuated form and a vector which carries at least the dep34 gene according to SEQ ID ...

07/27/06 - 20060166338 - Alleles of the mqo gene from coryneform bacteria
The invention relates to mutants and alleles of the coryneform bacterium mqo gene which encodes malate quinone oxidoreductases which contain any amino acid apart from L-serine at position 111, or a comparable position, in the amino acid sequence, and to processes for fermentatively preparing amino acids, preferably L-lysine, L-tryptophan and ...

07/27/06 - 20060166337 - Process for producing optically active erythro 3-cyclohexylserines
(wherein, R1 means an alkanoyl group having 1-10 carbons, a benzoyl group, a halogen-substituted alkanoyl group having 1-5 carbons or a halogen-substituted benzoyl group, and R2 means a phenyl group or a cyclohexyl group) is subjected to asymmetrical hydrolysis with L-aminoacylaseorD-aminoacylase, there by giving unreacted N-acyl-D-erythro3-substituted serine in the case ...

07/20/06 - 20060160192 - A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family having a pathway of glycogen biosynthesis disrupted
There is provided a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, having the glycogen biosynthesis pathway disrupted. ...

07/20/06 - 20060160191 - L-amino acid producing microorganism and a method for producing l-amino acid
An L-amino acid producing bacterium of the Enterobacteriaceae family is described, wherein the bacterium has been modified so as to not produce type I fimbrial adhesin protein is cultured in a medium to produce and excrete said L-amino acid in the medium, and collecting said L-amino acid from the medium. ...

07/06/06 - 20060148041 - Method for fermentative production of amino acids and amino acid derivatives of the phosphoglycerate family
A microorganism strain suitable for fermentative production of amino acids of the phosphoglycerate family or derivatives thereof and producible from a starting strain, is based upon a starting strain having an increased activity of a yfiK-gene product or of a gene product of a yfiK homologue. The microorganism strain is ...

06/29/06 - 20060141586 - Method for producing l-amino acids using bacteria of the enterobacteriaceae family
There is disclosed a method for producing an L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of L-arabinose permease. ...

06/29/06 - 20060141585 - Microorganisms and processes for enhanced production of pantothenate
The present invention features improved methods for the enhanced production of pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities and having modified methylenetetrahydrofolate (MTF) biosynthetic enzyme activities. In particular, the invention features methods for enhancing production of desired products by increasing levels of a key intermediate, ketopantoate, ...

06/22/06 - 20060134760 - Process for the production of l-amino acids using strains of the family enterobacteriaceae that contain an attenuated frur gene
A process for the production of L-amino acids, in particular L-threonine, in which the following steps are carried out: (a) fermentation of the microorganisms of the family Enterobacteriaceae producing the desired L-amino acid, in which the fruR gene or nucleotide sequences coding therefor are attenuated, in particular are switched off, ...

06/01/06 - 20060115878 - Method for producing l-amino acid
In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and collecting the L-amino acid from the medium, a Gram-negative bacterium having the Entner-Doudoroff pathway and modified ...

05/18/06 - 20060105434 - R-hydroxynitrillyases havign improved substrate tolerance and the use thereof
The invention related to R-hydroxynitrillyases from the family of Rosaceae that are characterized by an improved substrate tolerance and increased stability. In the active center of the R-hydroxynitrillyases either a) an alanine group is substituted by glycine, valine, leucine, isoleucine, or phenylalanine or b) a phenylalanine group is substituted by ...

04/06/06 - 20060073577 - High succinate producing bacteria
The invention relates to a hybrid succinate production system that has a high capacity to produce succinate under aerobic and anaerobic conditions. The metabolic engineering of a hybrid bacterial succinate production system that can function under both aerobic and anaerobic conditions makes the production process more efficient, and the process ...

03/23/06 - 20060063240 - Method for producing an l-amino acid using a bacterium with an optimized level of gene expression
A method is provided for obtaining an L-amino acid or nucleic acid-producing bacterium belonging to the genus Escherichia with an optimized level of expression of the gene which influences the distribution of carbon flow, such as the sucAB genes, comprising introducing into the chromosome of the bacterium a set of ...

03/23/06 - 20060063239 - Process for the production of amino acids without trehalose
The invention relates to a method for producing an amino acid comprising culturing a microorganism of the genus Corynebacterium or Brevibacterium wherein said microorganism is partially or completely deficient in at least one of the gene loci of the the group which is formed by otsAB, treZ and treS, and ...

03/23/06 - 20060063238 - Method for the preparation of l-amino acids from d-amino acids
The invention relates to recombinant microorganisms which, in comparison to the starting organism, have a higher concentration or activity of a D-amino acid oxidase, of an L-amino acid dehydrogenase, of an NADH cosubstrate regenerating enzyme and, if necessary, of a catalase. The invention also includes methods for preparing L-amino acids ...

03/16/06 - 20060057685 - Method for producing abnormal amino acids using a bacterium of the enterobacteriaceae family having all acetohydroxy acid synthases inactivated
A method for producing abnormal amino acids is provided, such as norleucine and norvaline, using a bacterium of Enterobacteriaceae family, particularly a bacterium belonging the genus Escherichia which has all acetohydroxy acid synthases (AHASes) inactivated. ...

02/23/06 - 20060040365 - Use of phosphoketolase for producing useful metabolites
The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention ...

02/23/06 - 20060040364 - Dna coding for a protein which imparts l-homoserine resistance to escherichia coli bacterium, and a method for producing l-amino acids
A bacterium which has an ability to produce an amino acid and in which a novel rhtB gene encodes a protein having an activity of making a bacterium having the protein L-homoserine-resistant is enhanced, is cultivated in a culture medium to produce and cause accumulation of the amino acid in ...

02/16/06 - 20060035348 - Method for producing an l-amino acid using a bacterium having enhanced expression of the pcka gene
The present invention relates to a method for producing L-amino acids, such as L-tryptophan, L-phenylalanine, and L-tyrosine, using a bacterium belonging to the genus Escherichia, and wherein the L-amino acid productivity of said bacterium is enhanced by enhancing a PEP carboxykinase activity, which is coded by the pckA gene. ...

02/16/06 - 20060035347 - Polynucleotides encoding polypeptides involved in amino acid biosynthesis in methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in amino acid biosynthesis in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

02/16/06 - 20060035346 - Process for producing l-amino acids by fermentation of a mixture of glucose and pentoses
A process for producing an L-amino acid, such as L-isoleucine, L-histidine, L-threonine and L-tryptophan, using bacterium belonging to the genus Escherichia is provided which comprises cultivating the L-amino acid-producing bacterium in a culture medium and collecting the L-amino acid from the culture medium, wherein the culture medium contains a mixture ...

02/16/06 - 20060035345 - Process for the production of beta-amino acids using acylase
The present invention relates to a Variovorax sp. which produces an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a Burkholderia sp. which produces both an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce ...

02/09/06 - 20060030011 - Polynucleotides encoding polypeptides involved in the stress response to environmental changes in methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in the stress response to environmental changes in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

02/09/06 - 20060030010 - Polynucleotides encoding polypeptides involved in intermediates metabolism of central metabolic pathway in methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in central intermediates metabolism in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

02/09/06 - 20060030009 - Amino acid producing strains belonging to the genus escherichia and a method for producing an amino acid
Amino acids such as threonine, homoserine, isoleucine, lysine, valine and tryptophan are produced using a bacterium belonging to the genus Escherichia which has been constructed from a sucrose non-assimilative strain belonging to the genus Escherichia and which harbors sucrose non-PTS or PTS genes and has an ability to produce the ...

01/26/06 - 20060019356 - Polynucleotides encoding polypeptides involved in intermediates metabolism of the central metabolic pathway in methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in central intermediates metabolism in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

01/26/06 - 20060019355 - L-amino acid-producing microorganism and method for producing l-amino acid
L-amino acids are produced by culturing a microorganism which has an ability to produce the L-amino acid, but has been modified so that expression of the ybjE gene has been enhanced. The L-amino acid is collected from the culture medium or from the microorganism. ...

01/19/06 - 20060014258 - Dna coding for a protein which imparts l-homoserine resistance to escherichia coli bacterium, and a method for producing l-amino acids
A bacterium which has an ability to produce an amino acid and in which a novel rhtB gene encodes a protein having an activity of making a bacterium having the protein L-homoserine-resistant is enhanced, is cultivated in a culture medium to produce and cause accumulation of the amino acid in ...

01/12/06 - 20060008886 - Portable shooting house
A hunting house, comprising: an elongated tongue 150, a removable axle 350, a framework 700, and a camouflaged exterior 650 fitted over said framework 700. ...

01/05/06 - 20060003423 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced succ or sucd gene
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which at least one or more of the genes chosen from ...

12/01/05 - 20050266535 - Nucleotide sequences which code for the mete gene
and processes for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the metE gene is present in enhanced form, and the use of the polynucleotide sequences as hybridization probes. ...

12/01/05 - 20050266534 - Nucleotide sequences which code for the csta gene
The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the cstA gene, and a host-vector system having a coryneform host bacterium in which the cstA gene is present in attenuated form and a vector which carries at least the cstA gene according to SEQ ID ...

11/24/05 - 20050260720 - L-amino acid-producing bacterium and a method for producing l-amino acid
An L-amino acid-producing strain of Escherichia coli is bred by modifying an Escherichia coli K12 strain or a derivative thereof so as to become resistant to L-valine and have an ability to produce one or more L-amino acids selected from the group consisting of L-tryptophan, L-phenylalanine, L-lysine, L-tyrosine, L-glutamic acid, ...

11/17/05 - 20050255566 - Nucleotide sequences coding for the pknd gene
An isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising: (a) a polynucleotide which is at least 70% identical to a polynucleotide coding for a polypeptide containing the amino acid sequence of SEQ ID No. 2, (b) a polynucleotide coding for a polypeptide containing an amino acid ...

11/03/05 - 20050244936 - Hydantoin-racemase
The instant invention is directed to a rec-hydantoin-racemase from Arthrobacter aurescens DSM 3747. Furthermore, the gene encoding for the racemase and plasmids, vectors and microorganisms comprising this gene are to be protected. Use in a process for the production of amino carboxylic acids or derivatives thereof. ...

11/03/05 - 20050244935 - Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
Isolated nucleic acid molecules, designated MCT nucleic acid molecules, which encode novel MCT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

10/27/05 - 20050239177 - Novel gene and method for producing l-amino acids
The present invention describes a bacterium which has an ability to produce an amino acid and in which the rhtC gene encoding a protein having an enhanced activity of imparting L-threonine resistance to a bacterium expressing the protein. Preferably, the bacterium further includes an rhtB gene encoding for a protein ...

10/27/05 - 20050239176 - Genes for heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic coryneform bacteria
A plurality of primer sets are designed based on a region where conservation at the amino acid level is observed among various microorganisms for known gene sequences corresponding to a gene coding for an enzyme of the L-amino acid biosynthetic pathway derived from Corynebacterium thermoaminogenes, preferably an enzyme that functions ...

10/27/05 - 20050239175 - Method for producing l-amino acid using bacteria belonging to the genus escherichia
There is provided a method for producing L-threonine, L-valine, L-proline, L-leucine, L-methionine and L-arginine using bacterium belonging to the genus Escherichia wherein L-amino acid productivity of the bacterium is enhanced by enhancing an activity of proteins coded by b2682 and b2683 genes, or protein coded by b1242 or b3434 gene. ...

10/06/05 - 20050221451 - Fermentation process for the preparation of l-amino acids using strains of the family enterobacteriaceae
The present invention relates to a fermentation process for the preparation of L-amino acids in which the following steps are carried out (a) fermentation of the microorganisms of the family Enterobacteriaceae producing the desired L-amino acid, in which microorganisms' pckA gene, and/or the open reading frames of yjfA and ytfP ...

10/06/05 - 20050221450 - Methods of making l-amino acids in coryneform bacteria using the sige gene
The present invention relates to an isolated polynucleotide from Corynebacterium glutamicum comprising a polynucleotide sequence chosen from the group consisting of (a) a polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ...

10/06/05 - 20050221449 - Nucleotide sequence of threonine operon irrepressible by isoleucine and method for producing l-threonine using transformed host cell containing the same
A nucleotide sequence of the threonine operon of E. coli with a deletion of all or part of a nucleotide fragment of −56 to −18, a recombinant vector containing the above nucleotide sequence, and a transformed host cell containing the recombinant vector are provided. A method for producing L-threonine comprising ...

10/06/05 - 20050221448 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an attenuated aceb gene
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which the aceB gene, or the nucleotide sequence which codes for ...

09/29/05 - 20050214912 - Method for producing an optically active amino acid
A method for producing an optically active amino acid comprising contacting a 5-substituted hydantoin with a group of enzymes including both a hydantoinase and a carbamoylase, wherein the method is carried out in an aqueous solution with a dissolved oxygen concentration of 1.5 ppm or less. Optically active amino acids ...

09/29/05 - 20050214911 - Method for producing l-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
A method for producing an L-amino acid, such as L-histidine, L-threonine, L-lysine, L-glutamic acid, and L-tryptophan, using bacterium belonging to the genus Escherichia which has increased expression of genes, such as those of the xylABFGHR locus, which encode the xylose utilization enzymes, is disclosed. The method includes cultivating the L-amino ...

09/22/05 - 20050208634 - Polynucleotides encoding polypeptides involved in one-carbon compound metabolism in methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in C1 assimilation in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. ...

09/15/05 - 20050202542 - Production method of d-alloisoleucine
The present invention provides a production method of D-alloisoleucine, a protected compound thereof or a salt thereof, which is industrially useful, and which efficiently produces D-alloisoleucine having a high purity, a protected compound thereof and a salt thereof, and more particularly, a method including steps (a) to (c): (a) carbamoylating ...

09/01/05 - 20050191733 - Corynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

09/01/05 - 20050191732 - Corynebacterium glutamicum genes encoding proteins involved in homeostasis and adaptation
Isolated nucleic acid molecules, designated HA nucleic acid molecules, which encode novel HA proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HA nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

08/18/05 - 20050181488 - Method for producing l-threonine using bacteria belonging to the genus escherichia
A method is disclosed for producing L-threonine using bacterium belonging to the genus Escherichia, wherein the bacterium has L-threonine productivity and has been modified to have enhanced expression of one or more of the following genes: glk, pgi, pfkA,, tpiA, gapA, pgk, eno, and pykA, which code for enzymes of ...

08/11/05 - 20050176114 - Microorganism producing l-threonine having inactivated galr gene, method of producing the same and method of producing l-threonine using the microorganism
Provided are a microorganism capable of producing L-threonine and having an inactivated galR gene, a method of producing the same and a method of producing L-threonine using the microorganism. The microorganism can be used to produce L-threonine in high yield. ...

08/11/05 - 20050176113 - Microorganism producing l-threonine having inactivated tyrr gene, method of producing the same and method of producing l-threonine using the microorganism
Provided are a microorganism capable of producing L-threonine and having an inactivated tyrR gene, a method of producing the same and a method of producing L-threonine using the microorganism. The microorganism can be used to produce L-threonine in high yield. ...

08/11/05 - 20050176112 - Process for the preparation of l-amino acids using strains of the family enterobacteriaceae
The invention relates to a process for the preparation of L-amino acids by the fermentation of recombinant microorganisms of the family Enterobacteriaceae, characterized in that a) the microorganisms producing the desired L-amino acid in which the yibD ORF, or nucleotide sequences coding for the gene product, or alleles, is (are) ...

08/04/05 - 20050170473 - Process for producing either optically active n-substituted beta-amino acid and optically active n-substituted beta-amino acid ester or optically active n-substituted 2-homopipecolic acid and optically active n-substituted 2-homopipecolic acid ester
which has a reverse steric absolute configuration to that of the compound represented by the formula (II). ...

08/04/05 - 20050170472 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced soda gene
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which at least the sodA gene, or the nucleotide sequence which ...

07/28/05 - 20050164357 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of the microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which the eno gene or nucleotide sequences or alleles which ...

07/28/05 - 20050164356 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of the microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which the malT gene or nucleotide sequences or alleles which ...

07/14/05 - 20050153403 - Process for preparing l-amino acids using strains of the enterobacteriaceae family
The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family. The microorganisms are characterized by the overexpression or enhancement of the yaaU ORF. The desired L-amino acid is isolated, with, optionally, constituents of the fermentation broth, and/or the biomass remaining in the ...

07/14/05 - 20050153402 - Corynebacterium glutamicum genes encoding regulatory proteins
Isolated nucleic acid molecules, designated MR nucleic acid molecules, which encode novel MR proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MR nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

07/14/05 - 20050153401 - Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids
A process is described for preparing optically active β-atninocarboxylic acids from racemic N-acylated β-aminocarboxylic acids by cnantiosclccthc hydrolysis of the N-acylated β-aminocarboxylic acid in the presence of a hydrolase by way of biocatalyst, wherein the N-acyl substituent of the N-acylated β-aminocarboxylic acid (I) exhibits Structure I in which R1, R2 ...

06/30/05 - 20050142646 - Process for the enzymatic preparation of enantiomer-enriched beta-amino acids
and to the use thereof in the enzymatic preparation of enantiomerically enriched β-amino acids. ...

06/23/05 - 20050136518 - Method for l-threonine production
A method for producing L-threonine using a microorganism is provided. In the method, additional one or more copies of each of the phosphoenolpyruvate carboxylase (ppc) gene and the threonine operon are integrated into a particular site of the chromosomal DNA of a microorganism, while its inherent ppc gene and threonine ...

06/16/05 - 20050130277 - Nucleotide sequences coding for the pknb gene
and a fermentation process for the preparation of L-amino acids using corynebacteria in which at least the pknB gene is amplified, and to the use, as hybridization probes, of polynucleotides containing the sequences according to the invention. ...

06/16/05 - 20050130276 - Mutated isopropylmalate isomerase
The present invention provides a polypeptide comprising an amino acid sequence in which at least one amino acid is deleted, substituted or added in an amino acid sequence of isopropylmalate isomerase derived from a microorganism belonging to coryneform bacteria, wherein a coryneform bacterium which produces the polypeptide comprising the amino ...

06/09/05 - 20050124048 - L-thereonine producing bacterium belonging to the genus escherichia and method for producing l-threonine
There is disclosed a method for producing L-threonine using bacterium belonging to the genus Escherichia wherein the bacterium has been modified to enhance an activity of aspartate-β-semialdehyde dehydrogenase. ...

06/09/05 - 20050124047 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an attenuated acek gene
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which the aceK gene, or the nucleotide sequence which codes for ...

06/02/05 - 20050118689 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
The invention relates to a process for the preparation of L-amino acids, in particular L-threonine. ...



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