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Chemistry: Molecular Biology And Microbiology > Micro-organism, Tissue Cell Culture Or Enzyme Using Process To Synthesize A Desired Chemical Compound Or Composition > Preparing Compound Containing Saccharide Radical > N-glycoside > > Nucleotide > Polynucleotide (e.g., Nucleic Acid, Oligonucleotide, Etc.) Polynucleotide (e.g., Nucleic Acid, Oligonucleotide, Etc.)Polynucleotide (e.g., Nucleic Acid, Oligonucleotide, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.04/19/07 - 20070087417 - Multiplex polynucleotide synthesis The invention provides a method of convergently synthesizing mixtures of either single stranded or double stranded polynucleotides. In one aspect, oligonucleotides that form components of such polynucleotides are synthesized on one or more microarrays, or other large-scale parallel solid phase synthesis platforms, after which they are amplified directly, or are ... 04/05/07 - 20070077628 - Polynucleotides, polypeptides and antibodies and use thereof in treating tsg101-associated diseases An isolated polynucleotide is provided. The isolated polynucleotide encodes a polypeptide having a sequence of at least 10 and no more than 500 amino acids, wherein said sequence is derived from the amino acid sequences of SEQ ID NO: 2, 4 or 6. Also provided are compositions and methods using ... 03/29/07 - 20070072272 - Industrial method for producing rna and system for carrying out said method The invention relates to an industrial method for producing an interest heterologous RNA and to a system for carrying out said production method consisting (1) in transforming mitochondrions of yeast cells free of mitochondrial RNA with a mitochondrial transcription vector comprising at least one copy of the DNA encoding said ... 03/22/07 - 20070065925 - Circovirus sequences associated with piglet weight loss disease (pwd) The genome sequences and the nucleotide sequences coding for the PWD circovirus polypeptides, such as the circovirus structural and non-structural polypeptides, vectors including the sequences, and cells and animals transformed by the vectors are provided. Methods for detecting the nucleic acids or polypeptides, and kits for diagnosing infection by a ... 03/22/07 - 20070065924 - Isolated polynucleotide sequence with ires activity Provided herein is an isolated polynucleotide sequence with internal ribosome entry site (IRES) activity, which directs translation initiation in an insect expression system in a cap-independent manner. In particular, the invention relates to an isolated polynucleotide comprises the 5′ UTR of perina nuda Picorna-like virus (PnV) that possesses IRES activity. ... 03/22/07 - 20070065923 - Peptides for discrimination of prions The aim of the present invention is to provide a non-intrusive way to isolate, concentrate and monitor the TSE disease-related pathogenic prion protein. The invention described several peptides and their ability to capture PrPSc from brain homogenate of prion disease infected animal and human. These eight peptides do not capture ... 03/15/07 - 20070059808 - Compositions and methods for inhibiting white spot syndrome virus (wssv) infection The present invention relates to a novel composition useful for inhibiting White Spot Syndrome Virus (WSSV) infection of crustacean animals, particularly those of the genera Penaeus sp. More specifically, the novel composition comprises a polypeptide whose amino acid sequence corresponds to at least a portion of Vp28, a surface protein ... 03/15/07 - 20070059807 - Mucosal immunization to prevent prion infection Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, ... 03/15/07 - 20070059806 - Nucleic acid molecules, polypeptides, antibodies and compositions containing same useful for treating and detecting influenza virus infection Polynucleotides and polypeptides which participate in influenza virus infection of cells and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding the polypeptides of the present invention. Also provided are methods of using such nucleic acid molecules, polynucleotides and antibodies directed thereagainst for diagnosing, treating and preventing ... 02/08/07 - 20070031941 - Methods and compositions for expressing negative-sense viral rna in canine cells The present invention provides novel canine pol I regulatory nucleic acid sequences useful for the expression of nucleic acid sequences in canine cells such as MDCK cells. The invention further provides expression vectors and cells comprising such nucleic acids as well as methods of using such nucleic acids to make ... 02/08/07 - 20070031940 - Methods for inducing differentiation of undifferentiated mammalian cells into osteoblasts The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts, including bone formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean bone ... 02/01/07 - 20070026503 - Polyomavirus cellular epitopes and uses therefor The present invention relates to HLA-A*02-restricted cellular epitopes within the VP1 polypeptide of a human polyomavirus, BK virus, which is associated with polyomavirus-associated nephropathy in kidney transplant patients. Preferred peptides correspond to amino acids residues 107-116, 108-116 and 44-52 of BKV VP1, and are processed in vivo in natural infection ... 02/01/07 - 20070026502 - Specificity exchangers that redirect antibodies to a pathogen Specificity exchangers and methods of making and using specificity exchangers are disclosed. Specificity exchangers are useful for preventing and treating human diseases including cancer and those resulting from pathogens such as bacteria, yeast, parasites, fungus, viruses, and the like. More specifically, specificity exchangers can redirect existing antibodies in a subject ... 12/21/06 - 20060286642 - Postweaning multisystemic wasting syndrome and porcine circovirus from pigs The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in ... 11/09/06 - 20060252132 - Influenza hemagglutinin and neuraminidase variants Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided. ... 10/26/06 - 20060240530 - Methods and compositions for infectious cdna of sars coronavirus The present invention provides a cDNA of a severe acute respiratory syndrome (SARS) coronavirus, recombinant SARS coronavirus vectors, and SARS coronavirus replicon particles. Also provided are methods of making the compositions of this invention and methods of using the compositions as immunogens and/or vaccines and/or to express heterologous nucleic acids. ... 09/14/06 - 20060205040 - Compositions for use in identification of adventitious viruses The present invention provides compositions, kits and methods for rapid identification and quantification of adventitious contaminant viruses by molecular mass and base composition analysis. ... 08/24/06 - 20060188967 - Method for extracting dna from organisms A method for the indirect extraction of DNA greater than 300 kb in size from non-cultivatable organisms contained in an environmental sample is disclosed. The method comprises isolating the organisms from the sample and embedding the isolated organisms in a block of agarose where the organisms are subsequently lysed and ... 07/27/06 - 20060166332 - Method for ligating nucleic acids and molecular cloning The invention provides cells and methods of circularizing linear DNA molecules. The cell is an isolated Escherichia coli cell which transiently expresses the Cre recombinase protein from an integrated Cre recombinase gene, and which is at least transiently repressed for RecBCD activity. The cells are used in a method of ... 07/27/06 - 20060166331 - Apparatus and method for preparative scale purification of nucleic acids Apparatus and methods are described for pharmaceutical grade manufacture extrachromosomal nucleic acids from cell lysates using flotation to separate and eliminate undesired insoluble cellular debris including chromosomal DNA from the lysates. A gas is introduced to controllably generate bubbles that reduce the density of the cell debris and create a ... 06/15/06 - 20060127989 - Antigenic fragment of human t-lymphotropic virus Antigenic fragments of human T-lymphotropic virus (HTLV), their fusion proteins with glutathione Stranferase (GST) or thioredoxin (Thio), and a process for producing the fusion proteins thereof. The antigenic fragment of HTLV comprises the amino acid sequence of SEQ ID Nos: 3 or 4. ... 06/15/06 - 20060127988 - Synthetic nucleic acid molecule compositions and methods of preparation A method to prepare synthetic nucleic acid molecules having reduced inappropriate or unintended transcriptional characteristics when expressed in a particular host cell. ... 06/08/06 - 20060121580 - Binding molecules against sars-coronavirus and uses thereof The present invention provides binding molecules that specifically bind to SARS-CoV, nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules are capable of specifically binding to SARS-CoV and can be used in the diagnosis, prophylaxis ... 06/08/06 - 20060121579 - Regulated nucleic acid expression system The present invention provides nucleic acid constructs, expression systems, and methods relating to the regulation of gene expression. The invention may be applied to regulate the expression of any coding sequence of interest, including those coding for viral components necessary for the packaging of viral particles. ... 05/25/06 - 20060110803 - Antigenic peptides of sars coronavirus and uses thereof The present invention pertains to antigenic peptides of SARS-CoV and their use in diagnostic test methods and in the treatment of condition resulting from SRAS-CoV. Furthermore, this invention provides antibodies capable of specifically recognizing the peptides of the invention. The antibodies can also advantageously be used in diagnostic test methods ... 04/13/06 - 20060078972 - Production of 5'-ribonucleotides The present invention describes a composition comprising at least 55% w/w (on sodium chloride free dry matter weight) of 5′-ribonucleotides and a process for the production of this composition comprising the steps of: (i) treating microbial cells to release the cell contents comprising RNA; (ii) separating the RNA present in ... 04/06/06 - 20060073576 - Hiv envelope-cd4 complexes and hybrids Env-CD4 complexes and hybrids are disclosed that expose cryptic epitopes that are important in virus neutralization. Methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided. ... 02/16/06 - 20060035344 - Double-stranded rna structures and constructs, and methods for generating and using the same The present invention relates to novel double-stranded RNA (dsRNA) structures and dsRNA expression constructs, methods for generating them, and methods of utilizing them for silencing genes. Desirably, these methods specifically inhibit the expression of one or more target genes in a cell of animal (e.g., a mammal such as a ... 02/02/06 - 20060024798 - Rna interference pathway genes as tools for targeted genetic interference Genes involved in double-stranded RNA interference (RNAi pathway genes) are identified and used to investigate the RNAi pathway. The genes and their products are also useful for modulating RNAi pathway activity. ... 02/02/06 - 20060024797 - Respiratory syncytial virus vaccines expressing protective antigens from promotor-proximal genes Recombinant respiratory syncytial virus (RSV) having the position of genes shifted within the genome or antigenome of the recombinant virus are infectious and attenuated in humans and other mammals. Gene shifted RSV are constructed by insertion, deletion or rearrangement of genes or genome segments within the recombinant genome or antigenome ... 01/26/06 - 20060019353 - Protein-nucleic acid conjugate for producing specific nucleic acid This invention provides inter alia an in vitro process for producing multiple specific nucleic acid copies in which the copies are produced under isostatic conditions, e.g., temperature, buffer and ionic strength, and independently of any requirement for introducing an intermediate structure for producing the copies. In other aspects, the invention ... 12/29/05 - 20050287648 - Protein transducing domain/deaminase chimeric proteins, related compounds, and uses thereof Disclosed are compositions for chimeric proteins comprising a protein transduction domain and a deaminase domain, mimetics or analog thereof, and uses of same. ... 12/29/05 - 20050287647 - Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes Methods for preparing cell lines that contain plant artificial chromosomes, methods for preparation of plant artificial chromosomes, methods for targeted insertion of heterologous DNA into plant artificial chromosomes, and methods for delivery of plant chromosomes to selected cells and tissues are provided. In particular, plant artificial chromosomes that are substantially ... 11/10/05 - 20050250186 - Methods and compositions for modulating telomerase reverse transcriptase (tert) expression Nucleic acid compositions comprising a TF-13 or TF-8 repressor binding site that acts to repress transcription of the telomerase reverse transcriptase (TERT) coding sequence, as well as vectors and constructs including the same, are provided. Also provided are methods of modulating, e.g., inhibiting, the TERT transcription repressing activity of the ... 11/03/05 - 20050244932 - Inverted orientation for a microplate An inverted microplate for conducting a thermocycled amplification reaction of polynucleotide. The microplate can comprise a main body having a first and second surfaces and a plurality of wells disposed in the first surface. Each of the plurality of wells can comprise a well opening and a well bottom and ... 10/20/05 - 20050233421 - Fed-batch fermentation process and culture medium for the production of plasmid dna in e. coli on a manufacturing scale A process for producing plasmid DNA E. coli cells comprises a pre-culture and fed-batch process. The culture media of the batch phase and the culture medium added during the feeding phase are chemically defined. The culture medium of the feeding phase contains a growth-limiting substrate and is added, for at ... 09/15/05 - 20050202541 - Three component chimeric antisense oligonucleotides This invention relates to antisense oligonucleotides that target mRNAs in cells as substrates for the cellular enzyme RNase H and thereby cause specific degradation of the targeted mRNA. The oligonucleotides have three components: an RNase H activating region, a complementary region and 3′ and 5′ ends. The invention optimizes each ... 06/30/05 - 20050142645 - Vectors, host cells, and methods for production of uridine phosphorylase and purine nucleotide phosphorylase Novel strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine phosphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified ... ### FreshPatents.com Support |