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Chemistry: Molecular Biology And Microbiology > Micro-organism, Tissue Cell Culture Or Enzyme Using Process To Synthesize A Desired Chemical Compound Or Composition > Preparing Compound Containing Saccharide Radical > N-glycoside > > Nucleotide

Nucleotide

Nucleotide patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

03/22/07 - 20070065922 - Biocatalytic synthesis of aminodeoxy purine n9-beta-d-nucleosides containing 3-amino-3-deoxy-beta-d-ribofuranose, 3-amino-2,3-dideoxy-beta-d-ribofuranose, and 2-amino-2-deoxy-beta-d-ribofuranose as sugar moieties
Purine N9-β-D-nucleosides containing 3-amino-3-deoxy-β-D-ribofaranose, 3-amino-2,3-dideoxy-β-D-ribofuranose, and 2-amino-2-deoxy-β-D-ribofuranose as sugar moieties are synthesized by biocatalytic transglycosylation of purine bases and the respective 3′-amino-3′-deoxyuridine, 3′-amino-3′-deoxythymidine and 2′-amino-2′-deoxyuridine as donors of the carbohydrate moiety, and the cells of Escherichia coli as a biocatalyst or glutaraldehyde (GA) treated cells of Escherichia coli as a ...

12/07/06 - 20060275874 - Purine-derived substance-producing bacterium and a method for producing purine-derived substance
A purine-derived substance is produced by culturing a Bacillus bacterium which has an ability to produce a purine-derived substance and has enhanced activity of an enzyme of the oxidative pentosephosphate pathway. The purine-derived substance is produced in the medium or the bacterial cells, and can be collected from the medium ...

11/23/06 - 20060263859 - Method for preparing 3'-amino-2',3'-dideoxyguanosine
Disclosed therein is a method for preparing the 3′-amino-2′,3′-dideoxyguanosine, comprising the steps of: (a) treating 3′-amino-3′-deoxythymidine and 2,6-diaminopurine with a pyrimidine nucleoside phosphorylase and a purine nucleoside phosphorylase to prepare 3′-amino-2′,3′-dideoxyribosyl 2,6-diaminopurine; and (b) converting enzymatically the 3′-amino-2′,3′-dideoxyribosyl 2,6-diaminopurine with an adenosine deaminase to prepare 3′-amino-2′,3′-dideoxyguanosine. According to the present ...

11/09/06 - 20060252131 - Deoxynucleoside kinase from insect cells for the synthesis of nucleoside monophosphates
Recombinant kinase remaining stable during the synthesis of necleoside monophosphate without the addition of stabilizing SH reagents, without stabilizing proteins and accepting all four natural deoxynucleotides, obtainable from insect cells such as e.g. Drosophila Melanogaster. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of ...

10/26/06 - 20060240529 - Process for the preparation of fludarabine phosphate from 2-fluoroadenine and fludarabine phosphate salts with amines or ammonia
The invention provides a process for the preparation of fludarabine phosphate from 2-fluoroadenine and 9-β-D-arabinofuranosyl-uracil using Enterobacter aerogenes (EBA). 2-Fluoroadenine is reacted with 9-β-D-arabinosyl-uracile in a water solution at pH=7 in the presence of EBA cell paste, to yield fludarabine. Fludarabine is then treated with acetic anhydride and the resulting ...

04/27/06 - 20060088918 - Novel polyphosphate:amp phosphotransferase
(wherein NMP represents nucleoside monophosphate, NDP represents nucleoside diphosphate, dNMP represents deoxynucleoside monophosphate, dNDP represents deoxynucleoside diphosphate, n represents degree of polymerization of the polyphosphate which is an integer of up to 100); (B) substrate specificity: specific to AMP, GMP, IMP, dAMP, and dGMP, also acting with CMP, UMP, dCMP, ...

02/16/06 - 20060035343 - Carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate
L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5′-monophosphate (UMP), cytidine and cytidine. 5′-monophosphate (CMP) are produced using a bacterium belonging to the genus Escherichia harboring a mutant carbamoylphosphate synthetase in which the amino acid sequence corresponding to positions from 947 to 951 in a wild type carbamoylphosphate ...

10/20/05 - 20050233420 - Method for producing cytosine nucleoside compounds
The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a bacterium having the enzyme activity. The invention also provides a method for specifically reducing an activity to degrade the substrates or the ...

09/22/05 - 20050208632 - Method for producing 2'-deoxyribonucleoside
A 2′-deoxyribonucleoside is produced by culturing a microorganism, which is transformed with a gene encoding a ribonucleotide reductase and in which 2′-deoxyribonucleoside degradation activity is decreased or eliminated by disrupting a gene encoding a purine nucleoside phosphorylase on chromosomal DNA, in a medium in which the microorganism can grow to ...

08/11/05 - 20050176110 - Process for chromatographic separation of nucleosides
The invention relates to a process for chromatographic separation and purification of natural and synthetic nucleosides, deoxynucleosides and corresponding bases by using cross-linked xylose isomerase. In particular, nucleosides are separated from biological material, especially industrial side streams. ...

08/04/05 - 20050170470 - Process for producing 2'-deoxyguanosine
The invention provides a process for producing 2′-deoxyguanosine, characterized in that the process includes reacting one compound selected from the group consisting of guanosine, guanosine 5′-monophosphate, and 2-amino-6-substituted purine with 2′-deoxynucleoside in the presence of nucleoside deoxyribosyl transferase and a hydrolase. According to the process of the present invention, 2′-deoxyguanosine ...

06/16/05 - 20050130274 - Enzymatic process for the synthesis of organo-fluorine compounds
There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be used to produce an 18F labelled fluoronucleoside compound. There is also described an enzyme derived from Streptomyces cattelya which has ...



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