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Chemistry: Molecular Biology And Microbiology > Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip > Involving Fixed Or Stabilized, Nonliving Microorganism, Cell, Or Tissue (e.g., Processes Of Staining, Stabilizing, Dehydrating, Etc.; Compositions Used Therefore, Etc.)

Involving Fixed Or Stabilized, Nonliving Microorganism, Cell, Or Tissue (e.g., Processes Of Staining, Stabilizing, Dehydrating, Etc.; Compositions Used Therefore, Etc.)

Involving Fixed Or Stabilized, Nonliving Microorganism, Cell, Or Tissue (e.g., Processes Of Staining, Stabilizing, Dehydrating, Etc.; Compositions Used Therefore, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

04/12/07 - 20070082377 - Cytotoxicity assays
Certain embodiments of the invention provide methods and kits for determining cell viability and measuring cytotoxicity. ...

03/29/07 - 20070072258 - Ultrasound-mediated high-speed biological reaction and tissue processing
Methods of fixing and processing tissue and samples on a membrane by using ultrasound radiation as a part of the method are presented. Ultrasound of a frequency in the range of 0.1-50 MHz is used and the sample or tissue receives 0.1-200 W/cm2 of ultrasound intensity. The use of ultrasound ...

01/04/07 - 20070003998 - Papanicolau staining process
A method for treating a biological sample with a Papanicolaou staining process is provided. The method comprises incorporating a detergent treatment into the staining process at any of various steps. The method has been found to advantageously reduce the number of artifacts produced during Papanicolaou staining. Also provided is a ...

12/21/06 - 20060286627 - Methods and kits for obtaining a metabolic profile of living animal cells
The present invention relates to growing and testing eukaryotic cells (e.g., animal or plant cells) in a multi-test format. In particular, the present invention provides methods and kits for obtaining a complex metabolic profile of animal cells. In addition, the present invention provides tools for assaying the effects of candidate ...

12/21/06 - 20060286626 - Selective chromophores
The invention further comprises a method for cell sorting, a method for cell targeting, as well as a method for cell identification. ...

12/07/06 - 20060275861 - In situ heat induced antigen recovery and staining apparatus and method
Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments for individually and independently processing a plurality of individual microscope slides. The apparatus preferably features independently movable slide support elements each having an individually heatable ...

11/02/06 - 20060246536 - Xenograft tissue control for histology
An embodiment of the invention is a method of using a xenograft as a control tissue for histology, comprising staining both a patient and a xenograft-derived control sample under substantially similar staining conditions, and assessing the staining outcomes of the two to determine whether the stain was effective for the ...

10/19/06 - 20060234332 - Predicting hepatotoxicity using cell based assays
Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, ...

10/12/06 - 20060228772 - Compositions and methods for preparing specimens for microscopic analysis
Compositions and methods for preparing a biological specimen for microscopic analysis. Fixing compositions and dewatering compositions are provided with methods for their use that improve sample preparation and result in greater detail being available in the prepared specimen. Such compositions and methods also render more quantitative analysis of prepared specimens ...

10/05/06 - 20060223138 - Method and apparatus for counting megakaryocytes
A method for counting megakaryocytes in a specimen is described. In the method, first, erythrocytes in the specimen are lysed and nucleic acid in the megakaryocytes is stained with a fluorescent dye, and thereby, a measurement sample is prepared. Next, the cells in the measurement sample are irradiated with excited ...

09/07/06 - 20060199243 - Cytological stain composition and methods of use
An aqueous staining reagent is described, a composition of a stain, a metal metabisulfite, and acid in water. The stain can be a cationic stain and is preferably thionin. The metal metabisulfite is preferably sodium metabisulfite. A method of preparing the aqueous staining reagent is described. Cytological methods for imaging ...

08/24/06 - 20060188954 - Method and apparatus for automated reprocessing of tissue samples
A method and apparatus of automatically reprocessing a specimen for microscopic examination is disclosed. Processing of a specimen for microscopic examination involves fixation of the specimen and preparation of the embedded specimen from the fixed specimen. There are instances where, once a specimen has been processed, it is necessary to ...

06/29/06 - 20060141554 - Site-specific labeling of affinity tags in fusion proteins
The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical ...

06/22/06 - 20060134732 - Methods and compositions for a microemulsion-based tissue treatment
The invention is directed to methods and compositions for deparaffinizing paraffin-embedded biological samples for subsequent tissue staining. The compositions are microemulsions that may include water/oil/surfactant microemulsions, and optionally a cosurfactant. The microemulsions enable deparaffinization without the use of xylene or toluene, and also enable solvent exchange without the use of ...

06/22/06 - 20060134731 - Stain characterization for automated cytology
A method is provided for analyzing and characterizing the formulation of a cell stain. In particular, the present invention provides a method of stain quality control using parameters derived from an imaging based automated cytology system to characterize the stain performance. ...

04/06/06 - 20060073541 - Lipophilic dyes and their application for detection of myelin
Embodiments of the present invention provide a method for selectively detecting myelin in tissue samples using lipophilic dyes and kits for detecting myelin in a sample. The dyes of the present invention are represented by the general formula A-B-E wherein A is a nitrogen heterocycle, B is a bridge moiety ...

03/02/06 - 20060046282 - Template methods and devices for preparing sample arrays
A method for preparing a microarray that includes placing at least one template over a first surface of the recipient block, wherein the template defines an array of openings and the recipient block has a plurality of receptacle holes, such that the array of openings are aligned with the plurality ...

02/23/06 - 20060040341 - Method of pre-treatment and staining of a biological sample and device for support of a biological sample and methods of using such device
There is disclosed a method of pre-treatment and staining, according to a protocol, of a biological sample disposed upon the surface of a carrier, the method comprising the step of recording at least one parameter relating to at least one protocol step in a non-volatile memory located either upon or ...

01/26/06 - 20060019332 - Deparaffinization compositions for dewaxing tissue specimens
Compositions and methods are provided for dewaxing wax-embedded biological specimens prior to histochemical analysis. The compositions and methods provided can effectively remove wax or improved wax-based embedding materials, particularly paraffin-based, from specimens during preparation for histochemical or other diagnostic analyses, while minimizing danger to users, achieving compatibility with automated use, ...

01/19/06 - 20060014238 - Method and system for automated detection of immunohistochemical (ihc) patterns
A method and system for automated detection of immunohistochemical (IHC) patterns. The method and system is able to automatically differentiate an epithelial cell part from a non-epithelial cell part of a digital image of a tissue sample to which an IHC compound has been applied. The method and system help ...

12/22/05 - 20050282245 - Use of a composition which regulates oxidation/reduction reactions intracellularly and/or extracellularly in a staining or sorting process
Staining mixtures comprising viable spermatozoa, a composition which regulates oxidation/reduction reactions intracellularly or extracellularly, and a DNA selective dye are disclosed. The cells contained in such suspensions tend to have a greater capacity for enduring the various process steps typically associated with the sorting of sperm cells into gender enriched ...

11/24/05 - 20050260698 - Selective staining of biomembranes using voltage-sensitive dyes
The present invention relates to a method for staining membranes, in particular, a method for selective staining of cells using voltage-sensitive dyes. ...

11/17/05 - 20050255540 - Buffer system for formalin fixatives
The invention relates to a buffer system comprising maleic acid and maleic acid dipotassium salt, for use with formalin-containing fixative solutions. The buffer system is soluble/miscible in dehydration solutions including alcohols, ketones, and monomethyl ethers, thereby preventing formation of precipitates in fluid lines and valve systems of automated tissue processors. ...

10/20/05 - 20050233410 - Compositions and methods for detecting precancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine
Presented is a method to detect precancerous states in mammalian cell and tissue samples comprising incubating a sample with solubilized 5,10,15,20-tetrakis(carboxyphenyl)porphine (TCPP), measuring TCPP fluorescence in the sample, and categorizing the sample as non-cancerous, precancerous or cancerous based on TCPP fluorescence, as correlated with the respective states of the cells. ...

10/20/05 - 20050233409 - Device and method for carrying out immunological marking techniques for thin-sectioned tissue
The invention relates to a device and a method for carrying out in an optimized and automated manner immunological marking techniques for thin-sectioned tissue (2b). A support plate (1) which can be automatically moved by means of a computer-controlled conveying device (20) and on which several thin sections of tissue ...

09/15/05 - 20050202524 - Tissue staining protocol and composition
An enhanced and particularly quick histological staining method is expressed in which a frozen tissue or deparafffinized tissue sample is briefly immersed in an eosin solution, used as a first dye, and then in a hematoxylin solution, used as a second die. The slide is rinsed and air-dried to make ...

09/08/05 - 20050196826 - Self calibrating detection
The present invention is an apparatus and method for calibrating a slide reader which reads probes, such as a biological slide reader. The apparatus has two matched lasers which are directed onto a non-fluorescing probe. Fluorescence from that probe is detected and signals are produced which represent that detection. The ...

08/18/05 - 20050181470 - Laser cell purification system
A process and apparatus for cell purification and ablation is disclosed. The present invention comprises a laser system which directs radiant energy at computer or manually selected individual cells thereby disrupting DNA, RNA and protein structure in those cells. The present invention produces a purified tissue section containing relatively intact ...

08/11/05 - 20050176089 - Methods and devices for retrieving a subject's physiological history from a biological sample analysis
Methods and devices for retrieving a subject's physiological history from a single sample or measurement are disclosed. Methods and devices for obtaining a blood glucose history from a single blood sample are disclosed. ...

08/11/05 - 20050176088 - Recipient block and method for preparation thereof
Disclosed is a recipient block for arraying a certain tissue sample into a desired position on a tissue microarray slide, comprising(a) an additive and (b) a wax. The present invention also discloses a method of preparing a recipient block, including (1) preparing an aqueous solution of an additive; (2) pouring ...

07/14/05 - 20050153388 - Marker for antidepressant therapy and methods related thereto
The present invention relates generally to methods for determining the effectiveness of ongoing antidepressant therapy via analysis of the association of Gsα with components of the plasma membrane or cytoskeleton of cells from peripheral tissues of the depressed individual as well as to methods involved in screening for effective antidepressant ...

07/14/05 - 20050153387 - Device and method for detecting cellular processes by means of luminescence measurements
The invention relates to a device for detecting a luminescence event in or in the immediate vicinity of a cell, a cell cluster, or a tissue, having the following elements: (a) a carrier element (1) having a surface (100) prepared for direct or indirect coupling of cells, and (b) at ...

06/30/05 - 20050142631 - Composition for the preparation of histological, autopsical, cytological samples
Composition based on alkyl C5-C20 and at least one aliphatic alcohol used for the preparation of histological, autoptic and cytological samples for examination, said composition being suitable for use in place of the various reagents employed up to s now according to rigidly fixed sequences. ...

06/23/05 - 20050136509 - Method and system for quantitatively analyzing biological samples
A method and system analyzing tissue or cell samples stored on laboratory slides or other media to identify properties of medical predictive and diagnostic relevance. The method and system includes automatically analyzing plural digital images created from plural biological tissue samples to which a staining reagent or a an immunohistochemical ...

06/09/05 - 20050124028 - Histological tissue specimen treatment
A tissue processor for processing tissue samples for histological analysis. The processor comprises two retorts, wax baths, reagent containers, a pump and valve. The vale distributes the reagent from one container to either retort. Separate reagent lines connect the wax baths to the retorts. A method of infiltrating a sample ...

06/02/05 - 20050118670 - Device and method for rapid tissue preparations for histological investigations
The device (1) for fast tissue processing for histological examination consists of a housing (2) that is covered by a transparent hood (70). A baseplate (3) divides the device (1) into an upper part (4a) and a lower part (4b). Several process chambers that are served by a transport mechanism ...



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