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Chemistry: Molecular Biology And Microbiology > Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip > Involving Hydrolase Involving HydrolaseInvolving Hydrolase patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.04/05/07 - 20070077614 - Uses of lp-pla2 in combination to assess coronary risk This invention relates to a method for assessing risk of Coronary Vascular Disease (CVD). Specifically, it relates to utilizing risk assessment from both Lipoprotein Associated Phospholipase A2 (Lp-PLA2) and C-reactive protein (CRP) in combination. In addition the invention relates to a method for assessing risk of Coronary Vascular Disease (CVD) ... 03/29/07 - 20070072254 - Manufacture of vitamin b6 A process for manufacturing a 3-unsubstituted, 3-monosubstituted or 3,3-disubstituted 9-acyloxy-1,5-dihydro-8-methylpyrido[3,4-e] [1,3]dioxepin (I) and optionally for manufacturing pyridoxine involves performing an addition reaction between a 4-methyl-5-alkoxy-oxazole (II) and a 2-unsubstituted, 2-monosubstituted or 2,2-disubstituted 4,7-dihydro-(1,3)-dioxepin (III) in the substantial absence of a solvent and a catalyst to give a product mixture consisting ... 03/22/07 - 20070065894 - Method for quantification of biological material in a sample Methods for the detection and/or quantification of a biological material in a sample. The method includes the steps of liquefying the sample (if necessary) and pouring the liquefied sample into the incubation vessel. The incubation vessel has a generally flat horizontal surface and the surface is divided into at least ... 03/22/07 - 20070065893 - Liquid-phase galactose oxidase-schiff's assay The invention provides an improved method for detecting cancer or a precancerous condition in a sample using an oxidation agent, such as galactose oxidase, and an aldehyde detection agent, such as Schiff's reagent that does not require the sample to be immobilized onto a solid support. The invention also provides ... 03/01/07 - 20070048815 - Enzyme detection technique A diagnostic test kit for detecting the presence or absence of an enzyme (e.g., leukocyte esterase) within a test sample is provided. The test kit comprises a substrate that is capable of being cleaved in the presence of the enzyme to release a nucleophilic aromatic compound. The kit also comprises ... 02/15/07 - 20070037240 - Control of protein activity using a conducting polymer A device having a substrate and an enzyme attached to the substrate. The substrate has a polymeric surface having at least two conductivity states. A minimum voltage that does not cause a redox reaction in the enzyme may be applied to the polymeric surface to change the conductivity state of ... 01/25/07 - 20070020716 - Coronary endothelial dysfunction This document provides methods and materials related to assessing coronary endothelial dysfunction (CED) conditions as well as methods and materials related to treating coronary conditions. For example, methods and materials for determining whether or not a mammal has CED by determining whether or not a sample from the mammal contains ... 01/25/07 - 20070020715 - Novel fluorogenic substrates for beta-lactamase gene expression in which W is a hydrogen, alkyl, substituted heteroalkyl, aryl, a heteroaryl, substituted heteroaryl or a CN; and, S is an integer from 0 to 5; W′ and W″ are independently hydrogen, alkyl, substituted heteroalkyl, aryl, substituted heteroaryl, (═O) or OR10; wherein R10 is hydrogen, substituted alkyl, heteroalkyl, substituted heteroalkyl, ... 01/18/07 - 20070015232 - Mitotic index assay Mitosis of cells is determined, particularly in the presence of a candidate agent, using cells comprising members of an enzyme fragmentation complex pair, where one of the members is in the nucleus and the other member is in the cytoplasm. By growing the cells where mitosis may occur, one adds ... 01/18/07 - 20070015231 - Assay for protein tyrosine phosphatases The invention relates in part to screening assays for identifying agents that alter the interaction between a protein tyrosine phosphatase (PTP) and its tyrosine phosphorylated polypeptide substrate, using fluorescence energy signals generated by detectably labeled substrates. Assays are provided in certain embodiments, including high throughput screening assays, wherein candidate agents ... 12/28/06 - 20060292656 - Lactamase amplification substrate An amplifiable β-lactamase substrate is provided comprising an enzyme donor fragment of β-galactosidase linked to form a ring to a β-lactam ring that is a substrate for lactamase and upon opening of the β-lactam ring the enzyme donor fragment becomes linearized. The cyclic substrate only weakly binds to the enzyme ... 12/28/06 - 20060292655 - 2-o sulfatase compositions and methods of analyzing therewith The invention relates to 2-O sulfatase and uses thereof. In particular, the invention relates to recombinantly produced 2-O sulfatase, functional variants and nucleic acid molecules that encode these molecules. The invention also provides methods of using 2-O sulfatase for a variety of purposes, including degrading and analyzing glycosaminoglycans (GAGs) present ... 12/21/06 - 20060286621 - Extraction methods and assays for feed enzymes This invention relates to methods of the detection of enzymatically active enzymes in feed added in the pre-pelleting stage. Further, this invention relates to the field of detecting thermotolerant enzymes added to feed in the pre-pelleting stage. In particular, the invention relates to the detection of a phytase enzyme, in ... 11/16/06 - 20060257961 - Sialic acid permease system This invention relates to purified sialic acid permease systems, and inhibitory agents of sialic acid permease systems. ... 11/02/06 - 20060246529 - Methods and compositions for assaying homocysteine The present invention relates to compositions and methods for assaying homocysteine (Hcy) and thus related moieties, e.g., S-adenosylhomocysteine (SAH) or adenosine. More particularly, assay methods that employ, mutant SAH hydrolase having binding affinity for Hcy, SAH or adenosine but has attenuated catalytic activity, are provided. The modified enzymes and fusion ... 10/26/06 - 20060240502 - Gtp cyclohydrolase ii as a target for fungicides The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method. ... 10/26/06 - 20060240501 - Defructosylation method The present invention is directed to a defructosylation enzyme originating from a plant, a method of defructosylating a fructosylated peptide or protein through use of the enzyme, and a method of measuring a fructosylated peptide or protein. ... 10/12/06 - 20060228767 - Test strip for determining concentration of creatinine in a body fluid sample Apparatus for determining concentration of creatinine in whole blood or plasma using a 1-methylhydantoinase (NMHase) catalyzed reaction, wherein the invention uses commercially available NMHase and thus eliminates prior art stabilization procedures for NMHase. Conveniently, known Trinder reagents and oxidative couplers are used for the indicator system. It has been found ... 09/28/06 - 20060216777 - Method for screening an agent for ability to inhibit heparanase activity The present invention provides a method for testing an agent for its potential to inhibit heparanase catalytic activity, comprising the steps of: interacting immobilized heparanase substrate binding protein on a solid support with labeled heparanase substrate to provide immobilized labeled heparanase substrate, interacting a heparanase enzyme solution with the immobilized ... 09/14/06 - 20060205028 - Active-site titration of glycosyl hydrolases The invention provides a method of screening for a property of a glycosyl hydrolase wherein the property is dependent on the concentration of the glycosyl hydrolase. The method comprises a step for determining the concentration of the glycosyl hydrolase by active site titration. ... 08/10/06 - 20060177885 - Delta 4,5 glycuronidase and methods of analyzing therewith The invention relates to Δ4,5 glycuronidase, related compositions, and methods of use thereof. ... 08/03/06 - 20060172364 - Novel chromogenic substrates based on alizarin, their applications and formulations containing such substrates An alizarin-based chromogenic substrate, a composition containing the substrate, and its use to detect the presence of an enzymatic activity. The substrate is particularly applicable in the field of biological diagnosis. ... 08/03/06 - 20060172363 - Peptide complexes containing phospholipase d The present invention provides peptide complexes comprising phospholipase D and one or morephospholipase D-interacting peptides. The peptide complexes are useful in screening assays foridentifying compounds effective in modulating the peptide complexes and in treating and/or preventing diseases associated with phospholipase D and it's interacting partners. In addition, methods for screening ... 07/20/06 - 20060160166 - Rapid triglyceride assay for use in pulp pitch control Enzymatic methods are provided for determining the surface triglycerides content in a sample of wood pulp. The methods preferably comprise reacting triglycerides which are present on the surface of the wood pulp fibers in the sample in the presence of a lipase to form glycerol and fatty acids, and then ... 06/29/06 - 20060141551 - Analytical method for detecting alkaline sphingomyelinase and kit for use in such method The use of an alkanoyl L-carnitine for preparing a medicament for treating the erectile dysfunction is described. ... 06/22/06 - 20060134716 - Electrospun enzyme-nanocomposite biosensing material The present invention provides biosensing material comprising polymer-enzyme nanocomposite fibers. A biosensor comprising such material may be obtained through an electrospinning process to yield a nonwoven mat, which retains enzyme activity. The large amount of available surface area obtained by the methods of the present invention provides unusually high sensitivity ... 06/22/06 - 20060134715 - Optically detectable organophosphonates in which X represents an optically detectable moiety, n is an integer with 1≦n≦20, R1 is an unbranched or branched alkyl group having 1 to 20 carbon atoms, and R2 is hydrogen or —CH2—O—R3 group, wherein R3 has the same meaning as R1. These compounds are useful as inhibitors of ... 06/08/06 - 20060121549 - Methods and devices for detecting pancreatic lipase A method and device for determining pancreatic lipase in an animal blood sample. In one aspect, the device includes a compartmentalized container for storing and reacting the reagents for use in the assay. In another aspect, the device include a multilayer device having a spreading layer and reagents layers with ... 06/08/06 - 20060121548 - Systems and methods for measuring sodium concentration in saliva Systems and methods for measuring saliva sodium concentration using a chromatographic reaction enable rapid-results, low-cost diagnosis of various medical conditions in an outpatient setting. In one embodiment, measured patient saliva sodium concentration is used by the patient or the patient's healthcare provider to guide medical decision making. In another embodiment, ... 05/25/06 - 20060110782 - Compositions and methods for modification of biomolecules The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating ... 04/13/06 - 20060078959 - Recombinant chondroitinase abc i and uses thereof The invention relates to chondroitinase ABC I and uses thereof. In particular, the invention relates to recombinant and modified chondroitinase ABC I, their production and their uses. The chondroitinase ABC I enzymes of the invention are useful for a variety of purposes, including degrading and analyzing polysaccharides such as glycosaminoglycans ... 04/06/06 - 20060073538 - In-vitro diagnostic medical devices for determining saliva volume The invention relates to a method of collecting saliva from the oral cavity for detecting a test substance, comprising the steps of (a) cleaning the oral cavity, (b) stimulating saliva secretion with a saliva-collecting solution, (c) removing the saliva-saliva collecting solution mixture from the oral cavity and collecting it in ... 02/16/06 - 20060035304 - Methods of oligosaccharide profiling for the detection of cancer The present invention provides methods for identifying oligosaccharides specific to cancer and methods for determining a strain of cancer in an individual. The present invention also provides methods for diagnosing cancer or a stage of cancer in an individual by detecting the presence or absence of specific cancer markers and ... 02/09/06 - 20060029992 - Devices and methods for the rapid, reliable detection and determiniation of acrylamide concentration in food substances and prevention of acrylamide formation in the same The present invention includes a device and associated analytical method to use for the sensitive detection and accurate, rapid determination of acrylamide in food substances. The present invention also relates to the use of a kit device and associated analytical method in which a user can quickly and easily ascertain ... 01/26/06 - 20060019326 - Use of three-dimensional microfabricated tissue engineered systems for pharmacologic applications The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, ... 01/19/06 - 20060014230 - Beta-lactamase detecting reagent composition, detection kit and detection method The present invention provides a reagent composition for detecting β-lactamase including as a β-lactamase detection substrate 3-[2,4-dinitrostyryl]-7-(2-thienylacetamido]-3-cephem-4-carboxylic acid, or 7-[2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxy-imino)acetamido]-3-(2,4-dinitrostyryl)-3-cephem-4-carboxylic acid, and at least one β-lactamase inhibitor selected from the group consisting of clavulanic acid, aztreonam, ethylenediaminetetraacetic acid, and cloxacillin, which composition can detect β-lactamases rapidly and easily with high ... 11/10/05 - 20050250170 - Determination of metal ions in solution by photoluminescence anisotropy The invention relates to compositions and kits for homogeneous fluorescence polarization (anisotropy) assays for detecting and quantifying metal ions in solution. Metal-dependent binding of a fluorescent ligand to an unlabeled macromolecule effects a measurable change in anisotropy as will the binding of metal ions to a fluorescent labeled macromolecule. Binding ... 11/10/05 - 20050250169 - Biological soil detector and method of using same A biological soil detector is provided, the detector comprising: a solid support member; a specific indicator immobilized on the solid support member; and the solid support and specific indicator positioned to facilitate contact with a liquid used to contact a surface. In another aspect, the invention provides a method for ... 11/10/05 - 20050250168 - Biological soil detector and method of using same A biological soil detector is provided, comprising: a solid support member; a specific indicator immobilized on the solid support member; and a retaining member holding the solid support thereon, the retaining member and solid support configured to facilitate contact between the solid support a surface. A method for the use ... 11/03/05 - 20050244913 - Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity This invention relates to methods for determining the activity of Lp-PLA2 in at least one sample from an animal. The invention also relates to methods for determining the inhibition of Lp-PLA2 activity in samples from animals that are administered an Lp-PLA2 inhibitor. ... 11/03/05 - 20050244912 - Methods for assaying inhibitors of s-adenosylhomocysteine (sah) hydrolase and s-adenosylmethionine (sam)-dependent methyltransferase The present invention relates to methods for assaying inhibitors for S-adenosylhomocysteine (SAH) hydrolases and assaying inhibitors for S-adenosylmethionine (SAM)-dependent methyltransferases. The methods are amenable for use in high throughput formats. Kits for performing the methods are also provided. ... 10/27/05 - 20050239158 - Enzyme-based monitoring device for thermal processing of objects This invention provides an enzyme-based monitoring device for monitoring the thermal impact of thermal processing on an object. The device comprises a sealed container enclosing a solid dehydrated mix comprising at least one enzyme and at least one first filler, sealing of the sealed container being obtained by means of ... 10/20/05 - 20050233402 - Heparinase iii hlgag fragments and uses thereof The invention relates to heparinase III and mutants thereof. Modified forms of heparinase III having reduced enzymatic activity which are useful for a variety of purposes, including sequencing of heparin-like glycosaminoglycans (HLGAGs), removing active heparan sulfate from a solution, inhibition of angiogenesis, etc. have been discovered according to the invention. ... 09/01/05 - 20050191719 - Modulators of b-lymphocyte activation, myosin-1f compositions and methods of use The present invention provides compositions and methods for modulating B-lymphocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating B-lymphocyte activation are provided. Compositions and methods for the treatment of disorders related to dysfunction or dysregulation of B-lymphocyte activation are also provided. Prophylactics and methods ... 07/21/05 - 20050158814 - Means and methods for detecting endoglycosidase activity The invention discloses a method for detecting an activity of an endoglycosidase. The method includes providing the endoglycosidase with a substrate of the endoglycosidase and detecting cleavage of the substrate. The method further includes at least partly inhibiting the transglycosidase activity of the endoglycosidase. The transglycosidase activity may be inhibited ... 06/23/05 - 20050136503 - Fluorescent ph indicators for intracellular assays Systems, including compositions and methods, for measuring pH, particularly in cells, organelles, and other samples. The compositions include pH-sensitive fluorescent and fluorogenic 2′,7′-dialkylfluorescein derivatives and associated nonfluorescent precursor compounds. The compositions may permit ratiometric measurement in the excitation spectrum and the emission spectrum. The methods include adding a precursor compound ... 06/09/05 - 20050124021 - Acetyl glucosaminyl inositol deacetylase, a mycothiol biosynthetic enzyme, and methods of use The present invention provides a family of bacterial acetyl glucosaminyl inositol deacetylases (MshB) with deacetylase activity against acyl glucosaminyl inositol and which play a key role in mycothiol biosynthesis. The invention deacetylases are characterized by a conserved 100 amino acid N-terminal region and three highly conserved histidine-containing regions and by ... ### FreshPatents.com Support - Terms & Conditions |