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Chemistry: Molecular Biology And Microbiology > Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip > Involving Glucose Or Galactose Involving Glucose Or GalactoseInvolving Glucose Or Galactose patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.04/19/07 - 20070087398 - Inactivated enzyme variants and associated process and reagent system The present invention relates to oxidoreductase apoenzyme variants which are enzymaticaily inactive but have coenzyme-binding properties. Further, the present invention relates to DNA sequences encoding these oxidoreductase apoenzyme variants, expression vectors containing such DNA sequences and the use of these oxidoreductase apoenzyme variants in diagnostic applications. ... 04/19/07 - 20070087397 - System and method of processing a current sample for calculating a glucose concentration A system and method of processing a test current for an analyte measurement in a fluid using a test strip and a test meter are disclosed. The method comprises sampling the test current at a pre-determined sampling rate to acquire a plurality of A/D conversions. The method also comprises filtering ... 04/12/07 - 20070082373 - Processes for regulating blood glucose in a mammal and novel polypeptides useful in nad biosynthesis The present invention relates to processes for regulating the blood glucose concentration of a mammal. A polypeptide useful in nicotinamide adenine dinucleotide (NAD) biosynthesis is also described. ... 03/01/07 - 20070048813 - Agent for assaying analyte of patient by enzyme This invention concerns an enzymatic reagent for measuring the analyte concentration in a patient by determination of oxidation rate of a reduced coenzyme. Said reagent is stabilized by the coenzyme reduction system which makes the reduced coenzyme in the reagent regenerate continuously throughout a long storage. This coenzyme reduction system ... 02/22/07 - 20070042450 - Multi-transduction mechanism based microfluidic analyte sensors In various aspects are provided a microfluidic and/or nanofluidic sensor that can provide an indication of the reliability of its measurement of the presence of an analyte in a sample under investigation, an analyte concentration in the sample under investigation, or both. The provided sensors, microfluidic devices, and methods of ... 02/15/07 - 20070037239 - Composition for measuring glucose having improved substrate specificity The present invention relates to a method for lowering activity with respect to maltose in glucose measurement comprising a step of reacting modified pyrroloquinoline quinone dependent glucose dehydrogenase subjected to amino acid sequence modification, wherein pyrroloquinoline quinone dependent glucose dehydrogenase is reacted in the presence of at least one type ... 02/15/07 - 20070037238 - Composition for suppressing pqqgdh reaction inhibition The present invention includes a step of reacting modified PQQGDH in the presence of one or more selected from the group consisting of succinic acid, glutaric acid, malonic acid, malic acid, phthalic acid, 2-ketoglutaric acid, 3,3-dimethylglutaric acid, pimelic acid, suberic acid, adipic acid and citric acid adipic acid, an amino ... 02/15/07 - 20070037237 - Method for improving substrate specificity of pyrroloquinoline quinone-dependent glucose dehydrogenase The present invention relates to a method for reducing activity for maltose in glucose measurement which comprises a step of reacting pyrroloquinoline quinone-dependent glucose dehydrogenase, the method comprising a step of keeping the pH acidic during the measurement reaction. ... 02/01/07 - 20070026476 - Compounds, methods, complexes, apparatuses and uses relating to stabile forms of nad/nadh The invention concerns stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives, enzyme complexes of these derivatives and their use in biochemical detection methods and reagent matrices. ... 01/25/07 - 20070020714 - Fluorescent indicator proteins having increased signal intensity to concentration of sugars and use thereof A protein biosensor having increased signal intensity to sugar concentration and the use thereof. A fluorescent indicator protein is described, in which fluorescent proteins of different emission ranges are fused to both ends of a binding protein undergoing a confornational change due to binding of sugars, such that a change ... 12/28/06 - 20060292650 - Spectroscopic analysis of a biological fluid reacted with an enzyme An apparatus is presented for estimating the concentration of an analyte using a combined enzyme-spectroscopic method. Examples are provided for the detection of glucose and lactate. A sample of biological fluid is mixed or contacted with an enzyme specific to the analyte of interest, and the reacting fluid is probed ... 12/21/06 - 20060286620 - Glucose analysis instrument Glucose analysis instrument for diabetics, comprising a measuring device for determining glucose concentration values, a displaying device for displaying glucose concentration values, a signaling device for generating a reminder signal, and a control and evaluation device that comprises a processor and a data memory and is used to determine reminder ... 11/23/06 - 20060263839 - Combined drug delivery and analyte sensor apparatus Embodiments of the present invention provide methods and apparatuses for analyte sensing combined with drug delivery in an integrated system. In an embodiment, a device may be utilized to sense an analyte, and in response to a measurement obtained therefrom, introduce a controlled amount of a drug to a user ... 11/23/06 - 20060263838 - Glucose dehydrogenase and production thereof The invention relates to novel PQQ-dependent soluble glucose dehydrogenases (sPQQGDH) from Acinetobacter and to a process for their preparation by overexpression in suitable microbial expression systems. ... 11/16/06 - 20060257959 - Glucose dehydrogenase Disclosed is a modified glucose dehydrogenase having pyrroloquinoline quinone as a coenzyme, wherein one or more amino acid residues in a region of 186-206 amino acid of water-soluble PQQGDH derived from Acinetobacter calcoaceticus or in an equivalent region from other species are replaced with other amino acid residues. Also disclosed ... 09/28/06 - 20060216773 - Method for determining the glucose concentration by fluorescence polarization The invention generally relates to a method for in vivo glucose monitoring in which the glucose concentration is measured by means of fluorescence polarization by detecting the change in viscosity, caused by changes in the glucose concentration. ... 09/21/06 - 20060211072 - Process, composition and kit for providing a stable whole blood calibrator/control The present invention is directed toward a stable calibrator and/or control, kit and process for using in a glucose monitoring instrumentation. Principally, the instant invention teaches a glycolyzed red blood cell component which has been treated with a glycolysis stabilizing effective amount of at least one non-crosslinking aldehyde compound which ... 09/07/06 - 20060199240 - Biosensor and method comprising enzymes immobilized on semiconductors The present invention provides a method and a device that utilizes functionalized semiconductor element for detecting presence and/or concentration of an agent in an assayed sample. The device of the present invention comprises: (i) a body having a surface comprising or having associated thereto semi-conducting material that can be excited ... 08/17/06 - 20060183179 - Method for quantitatively determining ldl cholesterols A method for quantitatively determining LDL cholesterol, including the steps of adding to serum a surfactant selected from among polyoxyethylenealkylene phenyl ethers and polyoxyethylenealkylene tribenzylphenyl ethers and a cholesterol-assaying enzyme reagent so as to preferentially react cholestrols in high density- and very low density-cholesterols among lipoproteins, and subsequently determining the ... 08/17/06 - 20060183178 - Polypeptide formulations and methods for making, using and characterizing them Embodiments of the invention include polypeptide formulations and methods for making, using and characterizing them. Embodiment of the invention include stabilized polypeptide formulations, for example stable glucose oxidase formulations that can be used with glucose sensors used in the management of diabetes. Another embodiment of the invention includes methods to ... 07/27/06 - 20060166299 - Proteins in type 2 diabetes The present invention relates to the use of naturally occurring compounds and derivatives thereof as markers for predisposition of diabetes related diseases. The invention also relates to a pharmaceutical composition for treatment of the diabetes related diseases. ... 07/13/06 - 20060154322 - Methods and systems for determining and controlling glycemic responses The present invention provides a method of determining a standard comestible Equivalent Glycemic Load of a dietary comestible comprising: (a) establishing a reliable glycemic response index for a standard comestible, wherein the index correlates glycemic response with glycemic load; (b) determining the glycemic response produced by a dietary comestible, and ... 06/15/06 - 20060127964 - Microprocessors, devices, and methods for use in monitoring of physiological analytes Described herein are microprocessors, devices, and methods useful for sweat and/or temperature detection that correlate more closely with changes in amperometric or charge signals related to analyte amount or concentration. The present invention provides methods for the establishment of more accurate sweat and/or temperature thresholds and new methods of compensation, ... 06/08/06 - 20060121547 - Diffusion layer for an enzyme-based sensor application A diffusion layer for an enzyme-based sensor application is provided, wherein the diffusion layer comprises (a) at least one polymer material, and (b) particles, typically hydrophilic particles, carrying the enzyme, the hydrophilic particles being dispersed in the at least one polymer material. ... 05/18/06 - 20060105412 - Sulfonate compound and fluorescent probe using the same one or a plurality of atomic groups B-SO3— are bonded to an atomic group A, B is a ring that is substituted by one or a plurality of electron-withdrawing groups, the electron-withdrawing group is at least one selected from the group consisting of an alkyl halide group, a nitro group ... 03/23/06 - 20060063218 - Micropressors, devices and methods for use in analyte monitoring systems The present invention comprises one or more microprocessors programmed to execute methods for improving the performance of an analyte monitoring device including prediction of glucose levels in a subject by utilizing a predicted slower-time constant (1/k2). In another aspect of the invention, pre-exponential terms (1/c2) can be used to provide ... 03/23/06 - 20060063217 - Coenzyme-binding glucose dehydrogenase The present invention provides a microorganism-derived soluble coenzyme-binding glucose dehydrogenase which catalyzes a reaction for oxidizing glucose in the presence of an electron acceptor, has an activity to maltose as low as 5% or less, and is inhibited by 1,10-phenanthroline. The invention also provides a method for producing the coenzyme-binding ... 02/23/06 - 20060040333 - Blood glucose monitoring kit A blood glucose monitoring kit includes a case constructed in the form of a bi-fold wallet which comprises an upper flap and a lower flap that are connected together through a fold. The case includes an outer layer constructed out of a water resistant and soft fabric and an inner ... 02/16/06 - 20060035300 - Method of measuring glucose concentration and glucose sensor with the use of glucose dehydrogenase The present invention relates to a technique for measuring a glucose level by utilizing a reaction system containing an enzyme and an electron carrier. In accordance with the glucose level measuring method of the present invention, glucose dehydrogenase with cytochrome C attached thereto or glucose dehydrogenase derived from a microorganism ... 02/09/06 - 20060029991 - Analyzer, analyzing method, and blood-sugar level measuring device An analyzer including an electrical information acquiring section for acquiring an electrical information by supplying an electricity to a skin of a subject; and a controller for acquiring a component value relating to an amount of a predetermined component included in a tissue fluid extracted via the skin of the ... 02/02/06 - 20060024774 - Sensor array A sensor array designed to be continuously indexed through a compatible blood glucose test monitor for the purpose of conducting multiple consecutive blood glucose measurements. The sensor array can be configured to substantially conform to a non-planar surface. In one embodiment, the sensor array includes first and second test sensors ... 01/05/06 - 20060003398 - Subcutaneous glucose electrode A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode ... 01/05/06 - 20060003397 - Test element The invention concerns test elements and methods for the optical detection of an analyte in a sample. The test element includes a support having at least one transparent portion, and a one-layer film positioned on the support. The film has a thickness when dry of less than about 10 μm. ... 12/29/05 - 20050287620 - Method of determining analyte level using subcutaneous electrode A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode ... 12/15/05 - 20050277164 - Blood glucose tracking apparatus and methods A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present ... 11/03/05 - 20050244910 - Methods for determining glycemic responses of foods The present invention provides precise methods for determining the glycemic responses of foods, including: (a) the incremental area under the glycemic response curve, (b) the Glycemic Index value of a food, (c) the Equivalent Glycemic Load or Glycemic Glucose Equivalent of a food, and (d) other similar measures. ... 11/03/05 - 20050244909 - Method for examination about peritoneal function The peritoneal function of a peritoneal dialysis patient is examined to evaluate the condition of the patient. An examining method comprises a step of alternately repeating introduction/drainage of a predetermined quantity of a peritoneal dialyzing fluid of an osmotic pressure and introduction/drainage of a predetermined quantity of another peritoneal dialyzing ... 10/27/05 - 20050239156 - Blood glucose tracking apparatus and methods A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present ... 10/27/05 - 20050239155 - Entrapped binding protein as biosensors The invention is directed to binding proteins, proteins comprising reporter groups, compositions of binding molecules comprising reporter groups in analyte permeable matrices, and their use as analyte biosensors both in vitro and in vivo. ... 10/27/05 - 20050239154 - A method of calibrating an analyte-measurement device, and associated methods, devices and systems The invention relates to a method for calibrating an analyte-measurement device that is used to evaluate a concentration of analyte in bodily fluid at or from a measurement site in a body. The method involves measuring a concentration, or calibration concentration, of an analyte in blood from an “off-finger” calibration ... 09/08/05 - 20050196821 - Method and apparatus for using alternative site glucose determinations to calibrate and maintain noninvasive and implantable analyzers A method and apparatus for calibrating noninvasive or implantable glucose analyzers uses either alternative invasive glucose determinations or noninvasive glucose determinations for calibrating noninvasive or implantable glucose analyzers. Use of an alternative invasive or noninvasive glucose determination in the calibration allows minimization of errors due to sampling methodology, and spatial ... 09/08/05 - 20050196820 - Apoenzyme reactivation electrochemical detection method and assay The invention discloses a methods in which dry reagent enzyme based electrochemical biosensors, which are in a relatively mature form due to the extensive amount of development pioneered by the blood glucose monitoring industry, may be simply adapted to perform tests for blood coagulation, enzymatic activity, or immunochemical assays for ... 09/01/05 - 20050191717 - Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. The methods and compositions employ modified bioburden testing and the detection of peptidoglycan. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major ... 08/25/05 - 20050186648 - Oct based method for diagnosis and therapy This invention relates to a method of diagnosing or treating a biological subject, such as a person or animal, comprising the steps of subjecting at least a microsample of the subject's tissue to a physiological perturbation and measuring the response of the microsample to the perturbation using optical coherence tomography ... 08/11/05 - 20050176084 - Non-or minimally invasive monitoring methods Methods for detecting the presence or amount of an analyte present beneath a target skin or mucosal surface of an individual are provided. The methods entail disruption of the target skin or mucosal surface, for example using a particle delivery method to provide micro-passages in the tissue. The methods further ... 08/04/05 - 20050170448 - Methods of manufacturing glucose measuring assemblies with hydrogels This invention relates to methods for reducing the presence of a compound in an ionically conductive material, e.g., for use in iontophoretic devices, wherein the presence of the compound interferes with detecting a selected analyte. Removal of the compound can typically take place either during or after the manufacture of ... 07/28/05 - 20050164322 - Small volume in vitro analyte sensor A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. ... 06/30/05 - 20050142628 - Use The present invention relates to the use of NAD(P)H oxidase inhibitors to increase cellular uptake of glucose and in the treatment and/or prevention of diseases caused by insulin resistance or diseases related thereto, such as type II diabetes. Specifically, the invention relates to a method for identifying an agent useful ... 06/23/05 - 20050136502 - Treatment of disorders associated with elevated blood glucose or blood pressure The present invention relates to methods for treating or delaying the onset of pathologies associated with elevated blood glucose and/or elevated blood pressure. The methods are directed to modulating, regulating, or inhibiting the expression or activity of Connective Tissue Growth Factor (CTGF) or fragments thereof. ... 06/23/05 - 20050136501 - Diagnostic test strip for collecting and detecting an analyte a fluid sample and method for using same A test strip for use of the determination of an analyte in a fluid sample according to one embodiment of the present invention is disclosed. The test strip comprises a base having a top and a bottom, a collection chamber that extends between the top and the bottom of the ... 06/23/05 - 20050136500 - Flow-through assay devices A flow-through assay device capable of detecting the presence or quantity of an analyte of interest is provided that is accurate, reliable, and easy-to-use. The device contains a substrate printed with a channel to facilitate the flow of a test sample to a detection working electrode. The detection working electrode ... 06/16/05 - 20050130249 - Methods for measuring analyte in a subject and/or compensating for incomplete reaction involving detection of the analyte The present invention relates to a predictive-kinetic method for use with data processing of a sensor-generated signal, as well as, microprocessors and monitoring systems employing such a predictive-kinetic method. Data from a transient region of a signal is used with suitable models and curve-fitting methods to predict the signal that ... 06/16/05 - 20050130248 - Biosensor carrying redox enzymes The present invention concerns an electrode carrying immobilized redox enzymes such that electric charge can flow between an electron mediator group to the enzyme cofactor by the use of boronic acid or a boronic acid derivative that acts as a linker moiety between the cofactor and the electron mediator group. ... 06/09/05 - 20050124020 - Micro/nano-fabricated glucose sensors using single-walled carbon nanotubes A novel glucose sensor utilizing hydrogen-specific gas sensing capability of single walled carbon nanotubes assembled on microelectrodes. Highly specific glucose sensing was demonstrated using buffered sample solutions with clinically significant concentrations. The approach enables a simple but powerful bio-sensor reliably operating with a completely new principle, and opens up novel ... ### FreshPatents.com Support |