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Chemistry: Molecular Biology And Microbiology > Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip > Involving Antigen-antibody Binding, Specific Binding Protein Assay Or Specific Ligand-receptor Binding Assay > Assay In Which An Enzyme Present Is A Label

Assay In Which An Enzyme Present Is A Label

Assay In Which An Enzyme Present Is A Label patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

03/15/07 - 20070059780 - Detection and amplification of ligands
A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an ...

01/18/07 - 20070015223 - Method of detecting substance to be analyzed
An object of the invention is to provide a quick, easy, and highly-sensitive method of detecting a substance to be analyzed, and to provide a method of supporting the analysis results by quantitativeness even if the amount of samples to be handled is a very small amount. The invention is ...

01/11/07 - 20070009968 - Photonic crystal biosensor structure and fabrication method
The invention provides sensor compositions and method of making sensors. ...

12/28/06 - 20060292642 - Immunoassay of phosphorylated proteins
An immunoassay of phosphorylated isoforms (phosphoforms, phosphoisoforms) of peptides, proteins, or their various related forms is described. In one embodiment, a sandwich-type “two-site” immunoassays involving two different recognition antibody partners, in which one antibody is specific for the protein or peptide and the other is specific for a known or ...

11/16/06 - 20060257946 - Serum biomarkers in ischaemic heart disease
Certain biomarkers and biomarker combinations are useful in a qualifying ischaemic heart disease status in a patient. A diagnostic methodology employing these biomarkers and combinations can distinguish between ischaemic heart disease and normal, as well as between cases of severe myocardial infarction versus mild myocardial infarction. ...

09/28/06 - 20060216761 - Isolation material for hormone disrupting substance, method of concentrating and method of clean-up
The present invention relates to an isolation material for an endocrine disrupter, which is prepared by immobilizing an anti-endocrine disrupter antibody to a graft-chain-containing carrier made of a polymeric material via covalent binding. According to the present invention, an isolation material for an endocrine disrupter, which is capable of specific ...

08/31/06 - 20060194264 - Affinity based system for detecting particulates in a fluid
This invention provides methods and apparatus for detecting and quantifying particulate matter suspended in a fluid. Specifically, the invention provides an integrated, affinity-binding based, analytical system comprising a platform for performing an affinity-binding based assay for specifically binding particulates including microbial cells, and a detection means for detecting the particulates ...

08/31/06 - 20060194263 - Small molecule mediated, heterogeneous, carbon nanotube biosensing
Nanosensors for detecting ananlytes and methods of detecting analytes have been developed in which a small molecule effector concentration is altered thereby causing changes in carbon nanotube conductance. ...

08/17/06 - 20060183166 - Arrays of supported biomembranes and uses thereof
A process for making a biomembrane array comprising providing a first substrate having a discrete zone and a second substrate. A first ink having a proteoliposome is then loaded onto the discrete zone to form a loaded zone. The loaded zone is then contacted to the second substrate such that ...

08/17/06 - 20060183165 - Combination of chemical differentiators and their applications in mass sensing-based chemical sensor systems
A sensing unit comprises a chemical sensing element and a transducer operatively associated therewith, wherein the chemical sensing element comprises at least one receptor for receiving a molecule of an analyte. An array of chemical sensing units is also provided, together with a chemical sensor system and a method of ...

08/03/06 - 20060172345 - Method for detecting low levels of a fusion protein
The invention relates to the detection of, among others, tumor-specific fusion proteins. Provided is a method for detecting a fusion protein in a sample, the fusion protein comprising an amino-terminal fragment and a carboxy-terminal fragment that each correspond to a native protein. The method comprises contacting the sample with at ...

06/01/06 - 20060115861 - Structure and method for releasing substance therefrom
A structure comprises at least a porous body holding a substance releasably, comprising a capping member for keeping the substance inside the pore and/or on at least a part of the entire surface of the porous body, and a connecting member for connecting the porous body and the capping member ...

04/13/06 - 20060078948 - Analytical method, analytical instrument, microarray and immunoassay of biological samples
An object of the present invention is to provide an analytical method and an analytical instrument with high capability of quantitative determination and reproducibility which can be used for detecting the minor difference between expression levels and measuring the protein concentration, for example. An analytical method for a biological sample ...

03/30/06 - 20060068450 - Microbead-filled microsystem and production method thereof
The invention relates to a micro-system intended to receive beads and to obtain a precise positioning of the beads at preset locations in the micro-system. This micro-system comprises a tank that has a cavity, the cavity being fitted with blocking elements allowing the beads to be ordered and stacked in ...

03/23/06 - 20060063210 - Histone deacetylase whole cell enzyme assay
The invention relates to enzymatic assays for protein deacetylases. More particularly, the invention relates to such assays utilizing whole cells. The invention provides assays which allow assessment of the level of a protein deacetylase activity in whole cells taken directly from the body of the mammal. ...

03/09/06 - 20060051816 - Rare cell detection using flat-panel imager and chemiluminescent or radioisotopic tags
Disclosed is a system using a large area flat panel imager which is specifically adapted for rare cell detection methods. The system generally includes an imager having a sample receiving surface which can provide a digital or electronic image of a sample deposited on the surface. The system also includes ...

03/02/06 - 20060046275 - Blood urea nitrogen (bun) sensor
A BUN (blood urea nitrogen) sensor containing immobilized carbonic anhydrase and immobilized urease for the in vitro detection of urea nitrogen in blood and biological samples with improved performance and precision characteristics. ...

03/02/06 - 20060046274 - Inhibin-a: a marker for differentiation, diagnosing and screening abnormal pregnancies
The present invention relates to a method, based on the hormone Inhibin-A, of diagnosing, screening and differentiating between normal pregnancies and abnormal pregnancies. The method can be used to differentiate between viable and non-viable pregnancies. Particularly, Inhibin-A can also be used in a method and kit for the diagnosis of ...

03/02/06 - 20060046273 - Homogeneous enzyme immunoassay for oral fluid
The present invention discloses homogeneous enzyme immunoassay systems, methods and kits useful for the qualitatively and quantitatively determination of analytes in oral fluid samples. The system involves a competitive enzyme immunoassay employing a conjugate comprising glucose-6-phosphate dehydrogenase (G6PDH) and an analyte. The methods and kits are particularly useful in the ...

02/09/06 - 20060029986 - Prevention and treatment of cardiovascular pathologies
wherein Z is C═O or a covalent bond; Y is H or O(C1-C4)alkyl, R1 and R2 are individually (C1-C4)alkyl or together with N are a saturated heterocyclic group, R3 is ethyl or chloroethyl, R4 is H or together with R3 is —CH2—CH2— or —S—, R5 is I, O(C1-C4)alkyl or H ...

01/05/06 - 20060003390 - Method for immobilizing conjugates in diagnostic tests
The invention concerns a method for the detection of an analyte in a sample using analyte-specific conjugates which have at least one heterologous group for an analyte-independent binding to a control zone. The present invention additionally provides new conjugates and reagent kits. ...

01/05/06 - 20060003389 - Detection of post-translationally modified peptides with liquid crystals
A method for differentiating between a post-translationally modified peptide and a peptide contained in a sample, comprising: (a) contacting the sample with a peptide attachment surface to create a peptidized surface, wherein the sample includes at least one functional group; (b) contacting the peptidized surface with a recognition reagent that ...

12/29/05 - 20050287608 - Diagnostic methods for protein profiling
Methods for establishing a protein expression profile of a biological sample, by contacting a biological sample with a ubiquitin-binding protein such that ubiquitinated and specific non-ubiquitinated protein (the IPS) bind to the ubiquitin-binding protein; isolating the IPS proteins; and analyzing the isolated IPS proteins, wherein an expression profile is generated. ...

12/22/05 - 20050282236 - Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, Y and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same. ...

12/08/05 - 20050272101 - Method for the early detection of renal injury
A method and kit for detecting the immediate or early onset of renal disease and injury, including renal tubular cell injury, utilizing NGAL as an immediate or early on-set biomarker in a sample of blood serum. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected ...

10/20/05 - 20050233390 - Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor
A device that includes a proteinaceous factor is disclosed. The proteinaceous factor is encoded by the nucleotide sequence of any one of SEQ ID NO.: 1, a degenerate variant of SEQ ID NO.: 1, and a complement of SEQ ID NO.: 1. The proteinaceous factor may be a recombinant. In ...

10/06/05 - 20050221395 - Methods and products based on oligomerization of stress proteins
In one aspect, the invention provides methods for determining the biological activity of heat shock proteins or heat shock protein-peptide complexes based on the ATPase activity or the multimeric structure of the heat shock proteins or heal shock protein-peptide complexes, and methods for screening agents that modulate the biological activity ...

09/29/05 - 20050214876 - Protein imprinted polymers with integrated emission sites
This invention provides protein or polypeptide imprinted polymers with integrated emission sites (PIPIES) for detecting the presence of a protein or polypeptide analyte comprising templated sites which are specific for the analyte. At or near the templated sites are selectively placed reporter molecules. A method is also disclosed for the ...

09/08/05 - 20050196815 - Method for detecting protein
An object of the present invention is to provide a method for detecting a protein using a nonradioactive label which is prevented to a smaller extent than in the case of the interaction of biotin/(strepto)avidin, and which achieves higher detection sensitivity than that of the detection system using DIG. The ...

09/01/05 - 20050191711 - Isolated components of dense microspheres derived from mammalian brain tissue and antibodies thereto
DMS present in the brain of individuals susceptible to cerebral amyloidosis disintegrate into DMS components to form cerebral amyloid plaques and other DMS components that are removed from the brain via circulating bodily fluids. Detecting the presence of these removed DMS components and/or antibodies thereto in circulating bodily fluids provides ...

08/25/05 - 20050186642 - Immunoassay reagents and methods of use thereof
The present invention provide reagents and methods of using the reagents, for example, on automated staining devices, that facilitate detection of two or more antigens in a sample simply and efficiently. ...

07/14/05 - 20050153372 - Compositions and method for regulation of calcium-dependent signaling in brain
Methods are provided for screening agents for activity as modulators of calcium signaling in brain tissue. ...

06/09/05 - 20050124008 - Homogeneous competition assays
Homogeneous assays wherein an unlabeled analyte is detected by displacing a more weakly binding tracer from a binding partner are described. The tracer has signal generating properties which differ when bound or unbound to the binding partner. ...



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