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Chemistry: Molecular Biology And Microbiology > Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip > Involving Antigen-antibody Binding, Specific Binding Protein Assay Or Specific Ligand-receptor Binding Assay > Involving A Micro-organism Or Cell Membrane Bound Antigen Or Cell Membrane Bound Receptor Or Cell Membrane Bound Antibody Or Microbial Lysate > Bacteria Or Actinomycetales

Bacteria Or Actinomycetales

Bacteria Or Actinomycetales patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

04/19/07 - 20070087395 - Method for detecting pathogenic organisms in fecal and salivary specimens and in biopsy material
The invention relates to a method for detecting pathogenic organisms, in particular Helicobacter pylori and H. heilmanii, in fecal, salivary and secretory samples by means of a double-antibody sandwich assay. The inventive method is characterized by dissolving or dispersing the sample having the pathogen antigen in a buffer solution and ...

03/08/07 - 20070054336 - Compounds and methods for diagnosis and immunotherapy of tuberculosis
Compounds and methods for diagnosing tuberculosis or for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more Mycobacterium proteins and DNA molecules encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable ...

03/08/07 - 20070054335 - Universal rapid test and method for detection of tuberculosis in multiple host species
A universal test apparatus for detecting tuberculosis (TB) in any of many different species of non-primate mammals is provided. The universal test apparatus includes a test site having a mycobacterial antigen cocktail comprising ESAT-6/CFP10 and 16 kDa/MPB83 polyfusion antigens, and a tracer having the ESAT-6/CFP10 polyfusion antigen and MPB83 antigen ...

03/08/07 - 20070054334 - Method for diagnosing infections
Antigens are removed from the surface of an organism, such as a microorganism, without disrupting the organism and releasing internal antigens of the organism. The free surface antigens of the organism may be used to determine the presence of infection in an animal due to the organism by determining the ...

02/22/07 - 20070042448 - Use of enzymes from helicobacter pylori as therapeutical targets
Methods for identifying molecules which inhibit the virulence or pathogenicity of Helicobacter pylori by modulating the activity of hydrolases encoded by genes amiA, mltD and slt. Compositions and diagnostic and treatment methods using hydrolases and molecules which inhibit them. ...

02/15/07 - 20070037231 - Methods and apparatus for detecting bacteria using an acoustic device
Methods for detecting bacteria are provided. A plurality of particles, each of which is coated with a capture agent having an affinity for the bacteria, is combined with the sample to form a plurality of analyte-particle complexes. The system also includes a transport arrangement for transporting the sample to the ...

02/15/07 - 20070037230 - Peptides for selectively and specifically binding bacillus anthracis spores and use thereof in landscape phages
Several peptides for selectively and specifically binding Bacillus anthracis spores are disclosed herein. It is contemplated that the isolated peptides will be incorporated into diagnostic probes. The diagnostic probes may include landscape page probes and antibody probes, as well as any other probes known in the art. Inventors contemplate that ...

02/08/07 - 20070031906 - Test system for detecting salmonella
Disclosed is a diagnostic test system for detecting Salmonella infections in a sample using monoclonal antibodies specific for SipC-protein. ...

02/01/07 - 20070026474 - Compositions and methods for detection of ehrlichia canis and ehrlichia chaffeensis antibodies
The invention provides methods and compositions for the detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies and antibody fragments. ...

02/01/07 - 20070026473 - Antibody profiles characteristic of tuberculosis state
Serum antibody assays capable of distinguishing cases of inactive TB from cases of active TB include a combination at least three M. tuberculosis protein antigens, at least one for which a positive response is consistent with inactive TB and antigens, and at least one for which a negative response is ...

02/01/07 - 20070026472 - Sterilization wrap with additional strength sheet
A sterilization wrap is provided. The sterilization wrap includes a first sheet that is configured for providing a barrier to prevent at least some bacteria from passing therethrough while allowing sterilization gas to pass therethrough. A second sheet is attached to the first sheet. The second sheet is located on ...

01/25/07 - 20070020712 - Use of ylqf, yqeg, yybq, and ysxc, essential bacterial genes and polypeptides
Disclosed are genes found in Streptococcus pneumoniae that are essential for survival for a wide range of bacteria. These genes are termed “S-ylqF,” “S-yqeG,” “S-yybQ,” “S-yerL,” and “S-ysxC.” These genes and the polypeptides that they encode, as well as homologs and orthologs thereof can be used to identify antibacterial agents ...

01/11/07 - 20070009975 - Method for detecting acid-resistant microorganisms in the stool
The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism, wherein (a) a stool sample of a mammal is incubated with at least two different monoclonal antibodies, fragments or derivatives thereof or aptamers under conditions allowing a complex formation of antigens of the ...

01/11/07 - 20070009974 - Methods and compositions to diagnose trichomonas infection
The present invention provides methods and compositions for diagnosing Trichomonas infection by detecting an antibody that specifically binds a Trichomonas α-actinin protein in a sample from a subject. ...

01/04/07 - 20070003991 - Method of diagnosing lawsonia intracellularis
The present invention relates to the field of animal health and in particular to Lawsonia intracellularis. In particular, the invention relates to a method of diagnosing Lawsonia intracellularis infection and a diagnostic test kit using Lawsonia intracellularis-specific antibodies. The invention also relates to the use of the method or test ...

12/28/06 - 20060292648 - Method of screening for inhibitors of osteopontin
Amino acids 136 to 142 and amino acids 162 to 168 of human osteopontin constitute two sites at which osteopontin interacts with α4 integrins. Products capable of disrupting those interactions are useful in therapy, particularly in the treatment of inflammatory diseases. ...

12/28/06 - 20060292647 - Reflex supplemental testing - a rapid, efficient and highly accurate method to identify subjects with an infection, disease or other condition
The present disclosure concerns methods, compositions and apparatus for detecting pathogens and/or molecular markers. In a particular embodiment, the pathogen to be detected may be Mycobacterium bovis or any other Mycobacterium species that causes tuberculosis in a mammal. However, the disclosed methods are not limited and virtually any type of ...

12/21/06 - 20060286613 - Recombinant adenylate cyclase of bordetella sp. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate c
Diagnostic testing and immunomonitoring that uses genetically detoxified Bordetella pertussis CyaA as a delivery system are effective in tracking any immune responses, such as those generated by infectious and non-infectious diseases, or vaccinations, for example. T cells previously stimulated by a given antigen can be restimulated in vitro by the ...

12/21/06 - 20060286612 - Spore specific antibodies
The invention relates to spore specific antibodies. Compositions and methods relating to the antibodies are provided along with the hybridomas that produce the antibodies. The antibodies are specific for the spores of B. anthracis relative to the vegetative form of the cells. The antibodies are also specific for the spores ...

12/14/06 - 20060281139 - Carrier and method for the detection of anti-borrelia antibodies and test kit for use in the diagnosis of lyme borreliosis infections
The invention relates to a carrier and a method for the detection of anti-Borrelia antibodies and a test kit for use in the diagnosis of Lyme borreliosis infections. ...

12/07/06 - 20060275848 - Diagnosis and treatment of microbacterial infections
The invention provides a method for detecting infection of an animal with a microorganism that causes a slow progressive disease, comprising providing the animal with a protein of the microorganism, or a functional part, derivative and/or analogue thereof, and measuring an immune response of the animal directed against the microorganism. ...

12/07/06 - 20060275847 - Method for assessing biofilms
An automated method for measuring the development of a biofilm, containing one or more fluorescent moieties, on a plurality of surfaces using a confocal imaging system including: a) a radiation source system for forming a beam of electromagnetic radiation including one or more wavelengths; b) an optical system for directing ...

11/30/06 - 20060269976 - Method for reducing lysozyme enzymatic activity
The present invention generally features therapeutic and diagnostic compositions and methods for increasing or decreasing the binding of a lysozyme polypeptide to a Treponema pallidum P17 polypeptide (Tp17) or a Tp17-like polypeptide. More particularly, the invention relates to compositions and methods for detecting, treating, or preventing a pathogen infection or ...

11/30/06 - 20060269975 - Corynebacterium glutamicum genes encoding proteins involved in dna replication, protein synthesis, and pathogenesis
Isolated nucleic acid molecules, designated RRP nucleic acid molecules, which encode novel RRP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing RRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further ...

11/16/06 - 20060257956 - Method and device for chemical or biological analysis by a sensor with a monolithic chamber in the form of a multi-microtubular sheaf and a lateral integration measuring transducer
A method and device for chemical or biological analysis by a sensor provided with a monolithic chamber in the form of a multi-microtubular sheaf and a lateral integration measuring transducer. The method improves the usual method for a sensor evaluation of an analyte concentration in a fluid sample by multi-canalising ...

11/16/06 - 20060257955 - Method for detecting escherichia coli
Described herein are methods of detecting an infection and for detecting the presence or absence of microorganisms, for example, wound pathogens in a sample, by contacting a sample with an enzyme produced and/or secreted by the bacteria, and detecting modification or the absence of modification of the substrate, as an ...

10/26/06 - 20060240494 - Biocidal molecules, macromolecular targets and methods of production and use
A method for identifying a compound that has a biocidal effect against a selected organism involves screening from among known or unknown peptide or non-peptide molecules, a test molecule that binds selectively to a target sequence of a multi-helical lid of a heat shock protein of the organism. The binding ...

10/19/06 - 20060234322 - Ehrlichia canis diva (differentiate infected from vaccinated animals)
Ehrlichia canis antigens that can be used to differentiate E. canis infected animals from animals that have been challenged with E. canis, e.g., vaccinated against E. canis, are disclosed. The invention also provides compositions and methods for determining the presence of E. canis antigens and antibodies. ...

10/19/06 - 20060234321 - Syphilis diagnostic tests and kits
The present invention provides methods and kits for determining whether a human subject is infected with T. pallidum, and isolated fragments of T. pallidum protein Tp92 that can be used in the methods and kits of the invention. ...

09/28/06 - 20060216765 - Apparatus, methods and systems for rapid microbial testing
A method for detecting microorganisms includes obtaining a sample from a source of interest and applying the sample to a selective growth medium to permit any microorganisms of interest in the sample to grow. Any microorganisms that have grown are harvested. An immunoassay is then conducted to detect the microorganism ...

09/21/06 - 20060211062 - Compositions and methods for detection of ehrlichia canis and ehrlichia chaffeensis antibodies
The invention provides compositions and methods for the detection and quantification of Ehrlichia chaffeensis or Ehrlichia canis, Ehrlichia chaffeensis or Ehrlichia canis antibodies, antibody fragments, and polypeptides. ...

09/21/06 - 20060211061 - Devices and methods for rapid detection of pathogens
Assay systems and methods are provided for detecting a target pathogen, such as a microorganism (e.g., bacterium, bacterial toxin) which may be present in a fluid or other location. The method can include linking a magnetic microparticle to a first epitope of the target microorganism in a fluid via a ...

08/31/06 - 20060194267 - Methods and kit for diagnosing tick borne illnesses
ELISA, Western Blot, and a peptide-based ELISA were applied to clinical specimens from patients with clinical symptoms of tick borne diseases, including Lyme disease. Peptides from different components of Borrelia during different cycles, including peptides from outer surface protein, leukocyte function associated antigens, immunodominant antigens, variable major proteins, and peptides ...

08/17/06 - 20060183170 - Pretreatment kit for saliva and pretreatment method for saliva
A pretreatment kit and a pretreatment kit for saliva in identification and quantitative determination of mutans streptococci by immunochromatography utilizing an antigen-antibody reaction, which can remove aggregation caused by mucin and chain formation of mutans streptococci in saliva in a simple operation and can efficiently flow out a complex of ...

08/10/06 - 20060177881 - Antibodies against type a botulinum neurotoxin
Antibodies for binding epitopes of BoNT/A and hybridomas which produce such antibodies are described. The antibodies of the present invention can be used in a method for detecting BoNT/A in a sample and/or in a method for purifying BoNT/A from an impure solution. In addition, the antibodies can be used ...

08/03/06 - 20060172355 - Novel proteins in enteroaggregative escherichia coli (eaec) useful for diagnosis and therapy of eaec infections
Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their ...

08/03/06 - 20060172354 - Novel proteins in enteroaggregative escherichia coli (eaec) useful for diagnosis and therapy of eaec infections
Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their ...

07/20/06 - 20060160159 - Identification of actinobacillus actinomycetemcomitans antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. ...

07/20/06 - 20060160158 - Target and method for inhibition of bacterial rna polymerase
 (854) GRE ...

07/13/06 - 20060154315 - Method of use of one step immunochromatographic device for streptococcus a antigen
A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or less extraction reagents, wherein the two reagents may be added to the assay chamber in no particular ...

07/13/06 - 20060154314 - Gfp-snap25 fluorescence release assay for botulinum neurotoxin protease activity
The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an affinity couple; and (iii) a portion of SNAP-25 that includes a BoNT/A, BoNT/C1 or BoNT/E recognition sequence containing a cleavage ...

07/06/06 - 20060148015 - Lectin pathway deficiency assay
The invention refers to an in vitro method of functionally determining at physiological conditions deficiencies in the lectin pathway of the complement system, the method comprising the steps of (a) providing a sample of mammalian blood, serum, plasma or another body fluid; (b) preventing in the sample the activation of ...

06/29/06 - 20060141546 - Bacterial test method by glycated label binding
A method for measuring the bacteria content of fluids such as urine and blood, in which a glycoprotein or glycopeptide is attached to the bacteria and a label attached to or inherent to the glycoprotein or glycopeptide provides a means for determining the amount of bacteria present. A preferred glycoprotein ...

06/15/06 - 20060127961 - Diagnostic assays for determination of dental caries susceptibility
The invention overcomes the limitations of the prior art by providing rapid assays for predicting the likelihood of caries development in patients. The assays allow implementation of appropriate dental care measures during a patient visit depending on the results of the assay. The assay utilizes the finding that caries-free children ...

06/15/06 - 20060127960 - Process for preparation of an agglutination reagent for rapid detection of typhoid
A process for the preparation of an agglutination reagent for rapid and early detection of typhoid, comprising the steps of: preparing Salmonella typhi specific antibody; preparing latex particles suspension; and coating said latex particles with the antibody. ...

06/15/06 - 20060127959 - Antibodies that bind m. tuberculosis polypeptides
Purified antibodies that bind to M. tuberculosis ERP protein are disclosed. In one a embodiment, a purified antibody, which binds specifically with a polypeptide comprising SEQ ID NO: 39 or SEQ ID NO: 41 is provided. In some embodiments the polypeptide has a theoretical molecular weight of about 28 kDa. ...

05/11/06 - 20060099661 - Detection and quantification of intracellular pathogens
The present invention provides methods and compositions for detecting bacteria of the Chlamydiaceae family in a biological sample. Methods include, for example, contacting a biological sample with an antibody that specifically binds to a chlamydial antigen displayed on the surface of a chlamydia-infected blood cell; and analyzing the sample using ...

04/27/06 - 20060088895 - Systems, methods and reagents for the detection of biological and chemical agents using dynamic surface generation and imaging
Techniques for the sensitive detection of analytes which combine the benefits of solution/suspension phase assay formats and the simplicity of solid phase/lateral flow assays are described. The assays can be performed in the solution/suspension phase using magnetic microspheres as a solid support. Subsequently a magnetic separation can be performed to ...

04/13/06 - 20060078952 - Method for identifying antimicrobial molecules which interfere with apolipoprotein n-acyltransferase activity
Products, compositions and methods useful for screening compounds or test molecules for their ability to modulate apolipoprotein N-acyltransferase activity. ...

04/13/06 - 20060078951 - Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
The present invention relates to a monoclonal antibody binding specifically to the p60 protein of Listeria monocytogenes, a hybridoma cell producing the monoclonal antibody, a test kit comprising the monoclonal antibody, and a method for detecting Listeria monocytogenes using the monoclonal antibody. The inventive monoclonal selectively recognizes only Listeria monocytogenes, ...

04/13/06 - 20060078950 - Identification of porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases
The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis. ...

04/06/06 - 20060073531 - Anti-chlamydial antibodies and uses thereof
The invention relates to anti-chlamydial antibodies and uses of anti-chlamydial antibodies for detection of the presence of chlamydia. ...

04/06/06 - 20060073530 - Methods and compositions involving sortase b
The present invention provides methods and compositions involving sortase-transamidases, including sortase B, and polypeptides that include a signal sorting sequence of NPQ/KTN/G. Methods of screening for inhibitors of Gram-positive bacteria as well as therapeutic, preventative, and research methods focusing on Gram-positive bacteria are also provided. ...

03/16/06 - 20060057654 - Methods for determining susceptibility to dental caries
The present invention provides methods for determining whether a human being is susceptible to dental caries. The methods each include the steps of measuring the amount of α-defensins HNP 1, HNP 2 and HNP 3 in saliva obtained from a human being, and determining whether a reduced amount of the ...

03/16/06 - 20060057653 - Detection of microorganisms with holographic sensors
A method for the detection of a cell comprises immobilizing the cell in a device also containing a sensor, and introducing a growth medium, wherein the sensor is sensitive to a product of the cell's growth; and detecting any change in an optical characteristic of the sensor. A device suitable ...

03/09/06 - 20060051822 - Methods for detecting bacillus thuringiensis cryet33 and cry et34 polypeptides
Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against coleopteran insects including red flour beetle larvae (Tribolium castaneum) and Japanese beetle larvae (Popillia japonica). Also disclosed are novel B. thuringiensis crystal toxin genes, designated cryET33 and cryET34, which encode the colepteran-toxic crystal proteins, CryET33 (29-kDa) ...

03/09/06 - 20060051821 - Methods and kits for use in the diagnosis and treatment of endotoxemia
The invention provides methods and kits for use in determining whether a patient may benefit from treatment with a toll-like receptor 4 (TLR4) antagonist, such as an antiendotoxin compound. ...

03/09/06 - 20060051820 - Method of examing staphylococcus aureus
Use the present invention enables detection of S. aureus in the sample in a short time and at a high sensitivity. ...

02/23/06 - 20060040332 - Mycobacterium tuberculosis epitopes and methods of use thereof
The invention provides novel Class I HLA-A2 and Class II HLA-DR4-restricted epitopes and methods for their use in detecting T-cells in peripheral blood specific for infection or latency of mycobacterial infection, including M. tuberculosis and M. leprae as others. For example, methods for diagnosing the presence of infection or exposure ...

02/16/06 - 20060035294 - Use of the protein maba (fabg1) of mycobacterium tuberculosis for designing and screening antibiotics
The invention especially relates to the protein MabA, also named protein FabG1, which is recombinant in a purified form, or the recombinant proteins derived from the protein MabA by mutation of at least one amino acid. The invention also relates to the uses of said proteins and to the crystallographic ...

02/16/06 - 20060035293 - Identification of actinobacillus actinomycetemcomitans antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. ...

02/02/06 - 20060024766 - Bifunctional molecules
A chimeric antibody conjugate comprising an antigen binding region of a non-human antibody and an immunoglobulin constant region which comprises at least one CH domain or epitope thereof, with the proviso that the constant region is not a naturally occurring FC fragment. A bifunctional molecule for use in labelling an ...

02/02/06 - 20060024765 - Method of inspecting staphylococcus aureus
Use the present invention enables detection of S. aureus in the sample in a short time and at a high sensitivity without cultivating the S. aureus. ...

01/26/06 - 20060019324 - Pknb kinase and pstp phosphatase and methods of identifying inhibitory substances
The present invention relates to a pknB kinase and a pstP phosphatase as well as their use for identifying antibacterial substances. ...

01/26/06 - 20060019323 - Recombinant adenylate cyclase of bordetella sp. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate c
Diagnostic testing and immunomonitoring that uses genetically detoxified Bordetella pertussis CyaA as a delivery system are effective in tracking any immune responses, such as those generated by infectious and non-infectious diseases, or vaccinations, for example. T cells previously stimulated by a given antigen can be restimulated in vitro by the ...

01/19/06 - 20060014228 - Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen
Bioelectronic devices for the detection of estrogen inlcude a collection of eukaryotic cells which harbor a recombinant lux gene from a high temperature microorganism wherein the gene is operably linked with a heterologous promoter gene. A detectable light-emitting lux gene product is expressed in the presence of the estrogen and ...

01/19/06 - 20060014227 - Methods, compositions, and kits for the detection of bacteria in a sample
The present invention includes compositions, kits, and methods useful for the detection of bacteria. These agents and methods are primarily directed to a method of detecting the presence of bacteria in a sample, involving incubating the sample with an agent that binds to bacteria, such as, e.g., an agent specific ...

01/05/06 - 20060003393 - Pathogenicity determinants which can be used as targets for developing means for preventing and controlling bacterial infections and/or systemic dissemination
The invention relates to a method for identifying and selecting a gene required for the proliferation in vivo of a pathogenic microorganism, comprising:—using a strain of the pathogenic microorganism,—generating mutants for inactivation in the genes encoding these factors,—determining the virulence of these mutants on an expiremental model of infection, and ...

12/29/05 - 20050287612 - Card-4 molecules and uses thereof
The invention provides methods of using CARD4 molecules to screen for modulators of LPS-induced cell signaling pathways. Also included are CARD-4 deficient mice, methods of modulating LPS-induced cell signaling pathways, and methods of treating or preventing bacterial infections. ...

12/15/05 - 20050277163 - Methods of use of one step immunochromatographic device for streptococcus a antigen
A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or less extraction reagents, wherein the two reagents may be added to the assay chamber in no particular ...

12/08/05 - 20050272106 - Methods and kits for detection of multiple pathogens
The present invention relates to methods of simultaneously detecting multiple infectious organisms, including methods of simultaneously determining the presence or absence in a sample of one or more members of a group of pathogens including at least one viral pathogen and at least one non-viral pathogen. The present invention also ...

12/08/05 - 20050272105 - Bacterial biosensors
A real-time, portable peptide-containing potentiometric biosensor that can directly identify bacterial spores. Two peptides for specific recognition of B. subtilis and B. anthracis Sterne may be immobilized by a polysiloxane monolayer immobilization (PMI) technique. The sensors translate the biological recognition event into a potential change by detecting, for example, B. ...

12/08/05 - 20050272104 - Method for detection of mycobacterium tuberculosis antigens in biological fluids
A method for detection of mycobacterium tuberculosis antigens in biological fluids provides immunoassay methods, diagnostic kits, and an immunochromatoraphic assay device for detection of Mycobacterium tuberculosis antigens in biological specimens, preferably body fluids and tissues. The preferred body fluids are blood, serum, plasma, urine, pulmonary fluid, sputum, cerebrospinal fluid, and ...

11/24/05 - 20050260694 - Modification of bioassays for detection of antigens characteristic of bacteria that are causative of ear and respiratory infections to eliminate false positive results caused by nasopharyngeal colonization of children
The present invention relates to modifying rapid immunochromatographic (“ICT”) tests for the detection of characteristic carbohydrate antigens of bacteria that are known to be causative of otitis media and respiratory diseases in children under the age of approximately 12 years. Children of this age group are also prone to nasopharyngeal ...

10/27/05 - 20050239148 - Method for enhancing staining of microorganisms
The invention is directed to a method and composition of matter for enhancing the staining of tissue or features of interest therein by applying an effective amount of a bile salt in combination with a special stain to a tissue suspected of harboring a microorganism or other feature of diagnostic ...

10/27/05 - 20050239147 - Method for diagnosing infectious diseases
A method for diagnosing the presence in an animal of an infection due to a microorganism in which a test sample obtained from the animal is exposed to a population of the microorganism and the presence of binding of the microorganism by an antibody in the test sample is determined. ...

10/20/05 - 20050233395 - Assays for detecting pathogenic respiratory bacteria
The present invention encompasses methods, assays and kits for the detection of pathogenic bacteria in a patient and for the differential diagnosis of pulmonary diseases associated with pathogenic bacteria from pulmonary diseases not associated with pathogenic bacteria. ...

10/20/05 - 20050233394 - Serological diagnostic method comprising positive control of introduction of human serum to be tested
The invention concerns the use of an antigen containing protein A, and in particular of Staphylococcus aureus as non-specific antigen added to bacterial serology reactions as positive control that the serum to be tested has been included. ...

10/06/05 - 20050221403 - Device for rapid detection and identification of single microorganisms without preliminary growth
This invention describes a device consisting of a micro channel plate, filter, and porous holder for filter, which is substituted by a pure agar block during method performance, and supportive structural elements. The device is intended for rapid detection and/or identification of microorganisms. Microorganisms are trapped by filtration in long ...

10/06/05 - 20050221402 - Bacterial small-molecule three-hybrid system
A transgenic bacterial cell comprising (a) a dimeric small molecule which comprises a first moiety known to bind a first receptor domain covalently linked to a second moiety known to bind a second receptor domain; (b) nucleotide sequences which upon transcription encode i) a first fusion protein comprising the first ...

10/06/05 - 20050221401 - Method of estimating risk of dental decay, apparatus of estimating risk of dental decay, system of estimating risk of dental decay and program of estimating risk of dental decay
The present invention provides a method of evaluating the risk of possible caries and the device, system, and program of the same, which is useful for the subjects to keep their mouth conditions best by measuring the chemical properties of saliva samples collected from the mouths of subjects to allow ...

09/15/05 - 20050202518 - Method for detecting and counting micro-organisms in a sample
The invention concerns a method for detecting and counting micro-organisms in a sample comprising the following steps: (a) selectively enriching the micro-organism sought in the sample, (b) conditioning said micro-organism, (c) immunomagnetic concentration of the conditioned microorganism, (d) fluorescent marking of the concentrated micro-organism, and (e) detecting and analyzing the ...

09/01/05 - 20050191714 - Proteome interaction mapping
Methods for identifying an organism with pesticidal activity are provided. The methods comprise binding the proteins expressed by the organism to a substrate (test proteins), contacting the substrate with proteins or lipids expressed by a target pest (target substances), and detecting whether the target substances have bound to the test ...

08/18/05 - 20050181465 - Device for detecting bacterial contamination and method of use
A device and method for detecting the presence or absence of a prokaryotic microorganism are provided, comprising the steps of identifying a protein, such as a microbial-specific protease that characterizes the presence of a specific prokaryotic microbe and thereby provides a marker for that microbe; detecting the protease that is ...

08/18/05 - 20050181464 - Novel purified polypeptides from bacteria
The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides. ...

08/11/05 - 20050176077 - Methods of inhibiting helicobacter pylori
This application relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection. ...

07/14/05 - 20050153376 - Superantigens
The invention provides superantigens SMEZ-2, SPE-G, SPE-H and SPE-J, as well as polynucleotides which encode them. Such superantigens have, inter alia, diagnostic and therapeutic application. ...

07/07/05 - 20050148039 - Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies
Disclosed is a cell wall C-polysaccharide antigen of Streptococcus pneumoniae which contains not more than 10% by weight of protein, and preferably less which has been purified with 0.1 N Na OH prior to deproteinizing. Also disclosed are polyvalent antibodies raised against Streptococcus pneumoniae which have been affinity purified by ...

07/07/05 - 20050148038 - Template-directed assembly of receptor signaling complexes
Transmembrane receptors in the signaling pathways of bacterial chemotaxis systems influence cell motility by forming noncovalent complexes with the cytoplasmic signaling proteins to regulate their activity. The requirements for receptor-mediated activation of CheA, the principal kinase of the Escherichia coli chemotaxis signaling pathway, can be demonstrated using self-assembled clusters of ...

06/30/05 - 20050142622 - Method for detecting microorganisms
Described herein are methods of detecting a wound infection and for detecting the presence or absence of microorganisms, for example, wound pathogens in a sample, by contacting a sample with an enzyme produced and/or secreted by the bacteria, and detecting modification or the absence of modification of the substrate, as ...

06/16/05 - 20050130240 - Carbohydrate encapsulated nanoparticles
The present invention provides carbohydrate encapsulated nanoparticles. In particular, the present invention provides metallic nanoparticles (e.g. gold nanoparticles) that are encapsulated in biologically important carbohydrate molecules, such as sugars, sugar derivatives, P-blood group antigens and analogues thereof. The present invention also provides methods of employing these carbohydrate encapsulated nanoparticles in ...

06/16/05 - 20050130239 - Immunoassay for h. pylori in fecal specimens using genus specific monoclonal antibody
The present invention provides a method for detecting H. pylori in fecal specimens. The present invention employs an immunoassay using genus specific monoclonal antibody to Helicobacter or Campylobacter on one side of the assay and H. pylori specific antibodies on the other side of the assay. The immunoassay will typically ...

06/09/05 - 20050124015 - Peptides for detection of antibody to anaplasma phagocytophilum
The invention provides compositions and methods for the detection and quantification of A. phagocytophilum (formerly known as Ehrlichia equi) antibodies and antibody fragments. ...

06/09/05 - 20050124014 - Stable isotope, site-specific mass tagging for protein identification
Proteolytic peptide mass mapping as measured by mass spectrometry provides an important method for the identification of proteins, which are usually identified by matching the measured and calculated m/z values of the proteolytic peptides. A unique identification is, however, heavily dependent upon the mass accuracy and sequence coverage of the ...

06/09/05 - 20050124013 - On-line apparatus and method for determining endotoxin levels
An apparatus and method for on-line testing for the presence of an endotoxin within a fluid sample from a fluid line. The apparatus is positioned in fluid communication with a fluid line to perform the on-line fluid testing for the presence of at least one endotoxin. The apparatus can include ...

06/02/05 - 20050118660 - Method and kit for identifying pseudomonas aeruginosa
A method of identifying a bacteria, such as Pseudomonas aeruginosa, in a sample, includes providing a sample suspect of comprising a bacteria to be identified, exposing the sample to an antibody specific for a lipoprotein of the bacteria and an agglutination reagent, allowing the sample to react with the antibody ...

06/02/05 - 20050118659 - Novel compounds
The invention provides BASB231 polypeptides and polynucleotides encoding BASB231 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. ...



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