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Chemistry: Molecular Biology And Microbiology > Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip > Involving Antigen-antibody Binding, Specific Binding Protein Assay Or Specific Ligand-receptor Binding Assay > Involving A Micro-organism Or Cell Membrane Bound Antigen Or Cell Membrane Bound Receptor Or Cell Membrane Bound Antibody Or Microbial Lysate > Animal Cell Animal CellAnimal Cell patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.04/12/07 - 20070082370 - Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane A Plasma or serum separation membrane that enables omitting centrifugal separation, is free from hemolysis attributed to destruction of red blood cells and realizes easy and rapid separation of plasma or serum from blood; and a filter apparatus including the plasma or serum separation membrane. In particular, a plasma or ... 04/05/07 - 20070077605 - Methods and apparatus for blood typing with optical bio-discs This invention relates to clinical diagnostic assays, related optical bio-discs, and a disc-reading apparatus. The invention is directed to methods and apparatuses for performing immunohematology assays using an optical bio-disc analysis system. The invention is further directed to an optical bio-disc for performing an immunohematologic assay including a substrate having ... 04/05/07 - 20070077604 - Diagnostic device and method A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte comprises a step in which the sample is received in a vessel flexible wall. In another step, an additive and particles ... 03/15/07 - 20070059782 - Magnetic particle tagged blood bank reagents and techniques Magnets and magnetic particle-labeled reagents are used to capture and/or release magnetic particle-tagged entities for immunohematology diagnostic testing purposes, especially tests performed in blood banking. The magnetic tagged entities may be tagged antibodies, tagged blood cells, tagged universal binding partners, especially tagged lectins and tagged Coombs reagent, and other binding ... 03/15/07 - 20070059781 - System for size based separation and analysis The invention relates to one or more size-based separation modules adapted to increase a concentration of a first analyte in a sample by at least 10,000 fold, wherein said first analyte has an initial concentration in said sample of less than 1×10−3 analytes/μL, and an analyzer for analyzing said first ... 03/08/07 - 20070054327 - Cell observation apparatus There is provided cell observation apparatus (10) comprising cell observation chamber (30) and optical observation means (70), the cell observation chamber (30) having, disposed thereinside, a pair of wells and a channel through which the wells communicate with each other so that cells of a cell suspension stocked in one ... 02/22/07 - 20070042443 - Hematopoietic cell phenotyping using free circulating cellular markers The present invention provides methods of identifying cluster of differentiation (CD) marker phenotype for hematopoietic cells using multiple soluble CD markers circulating in bodily fluid. In particular aspects, the CD marker phenotype can be used to classify the tumor type of a patient having a proliferative disorder. In other aspects, ... 02/15/07 - 20070037224 - Quantitative assays for pdgfr-beta in body fluids The present invention is directed to the detection and quantification of total PDGFR-β in body fluids, particularly serial changes of total PDGFR-β levels in a subject's body fluids. Further, the invention is directed to detecting and quantitatiing total PDGFR-β in conjunction with one or more other proteins, such as, oncoproteins, ... 02/08/07 - 20070031898 - Kit for determining polysaccharide-binding ability of mononuclear cells present in peripheral blood A kit for the determination of the ability of a peripheral blood mononuclear cell to bind to a polysaccharide herein provided comprises a detection reagent comprising a fluorescence-labeled immunostimulant polysaccharide; and a reference reagent comprising a fluorescence-labeled material of a polysaccharide different from that used in the fluorescence-labeled immunostimulant polysaccharide, ... 02/01/07 - 20070026468 - Tetrameric antibody complexes for blocking non-specific labeling of antigens A method for preventing or inhibiting non-specific binding reactions between a detection reagent and an antigen in an immunological assay is described. The method involves using tetrameric antibody complexes that can bind to the antigen and are comprised of two monoclonal antibodies of a first animal species linked to two ... 02/01/07 - 20070026467 - Lupus anticoagulant testing The present invention relates generally to the field of diagnostic screening and diagnostic assays. In particular, the present invention provides an improved, rapid, and efficient method of screening for antiphospholipid antibodies, such as lupus anticoagulants (LA). The invention also relates to a kit for screening plasma levels for antiphospholipid antibodies ... 01/25/07 - 20070020704 - Diaryl ureas with kinase inhibiting activity The present invention provides methods of using aryl ureas to treat diseases and conditions associated with signal transduction pathways comprising at least one of raf, VEGFR, PDGFR, p38 and/or FLT-3. The present invention also provides compositions and methods for identifying conditions and diseases which can be modulated with compounds of ... 01/25/07 - 20070020703 - Use of compositions comprising a soluble form of hla-g in the treatment of blood diseases The invention relates to the use of compositions comprising a soluble form of HLA-G in the treatment of blood and circulatory system diseases (anemias and ischaemias). ... 01/11/07 - 20070009969 - Determination of pregnancy status A method and kit for determining whether an animal is not pregnant, or is pregnant following a breeding. The level of expression of a pregnancy induced protein is determined in an animal for which pregnancy status information is desired and the level is compared to that of the level in ... 12/21/06 - 20060286610 - Identification of ligands by selective amplification of cells transfected with receptors The invention is directed to a method for identifying substances acting as ligands for transfected receptors by using transfected markers to measure receptor/ligand interactions. The present invention also relates to a method of identifying compounds which act as inverse agonists of the 5-HT2A receptor, the method comprising contacting a constitutively ... 11/30/06 - 20060269970 - Method for a fully automated monoclonal antibody-based extended differential Methods for differentially identifying cells in an instrument employ compositions containing a combination of selected antibodies and fluorescent dyes having different cellular distribution patterns and specificities, as well as antibodies and fluorescent dyes characterized by overlapping emission spectra which form non-compensatable spectral patterns. When utilizing the compositions described herein consisting ... 10/26/06 - 20060240490 - Methods and compositions for identifying target cell cytolytic lymphocytes in a sample Methods and compositions for identifying target cell cytolytic lymphocytes, e.g., T-cells, such as neoplastic cell cytolytic T-cells, in a subject are provided. In practicing the subject methods, the sample is contacted with a target cell stimulator, e.g., a neoplastic cell, and a detectably labeled granule membrane protein specific binding agent. ... 10/19/06 - 20060234316 - Methods for distinguishing type-1 from type-2 diabetes The present invention provides a new method for the prediction of, or diagnosis of, auto-immune diseases, thereby alerting the subject to the presence of, or propensity to develop, an auto-immune disease so that preventative or therapeutic regiments may be initiated or changed so as to treat, modulate or prevent expansion ... 10/19/06 - 20060234315 - Markers for sudden death in heart failure A method for screening, diagnosis or prognosis of sudden death in heart failure in a mammalian subject, for determining sudden death in heart failure in a mammalian subject, for identifying a mammalian subject at risk of sudden death in heart failure, or for monitoring the effect of therapy administered to ... 09/28/06 - 20060216762 - Extracting reagent for hydrophobic analyte in whole blood The present invention utilizes an extracting reagent to achieve quantitative detection of hydrophobic analytes from a biological test sample. The hydrophobic analytes can include steroids, and drugs. The biological test sample can include serum, plasma, whole blood, urine and spinal fluid. The hydrophobic analyte is preferably the drug cyclosporine, which ... 08/03/06 - 20060172346 - Methods of designing and producing novel compounds having improved binding affinity for cd154 or other trimeric proteins The present invention relates to methods for designing and producing novel CD40:CD154 binding interrupter compounds and methods using these compounds to treat conditions associated with inappropriate CD154 activation in a subject. This invention also relates to novel methods for screening candidate compounds for the properties of specifically binding CD154 and ... 07/20/06 - 20060160153 - Method to measure a t cell response and its uses to qualify antigen-presenting cells A method to characterize a T-cell response of a final population of T-lymphocytes resulting from the co-incubation of an initial population of T lymphocytes with a composition of antigen-presenting cells (APCs), said method comprising the steps of a) simultaneous measuring on a single cell basis at least two parameters: (i) ... 07/13/06 - 20060154308 - Buffy coat tube and float system and method A tube and float system for use in separation and axial expansion of the buffy coat is provided. The system includes a transparent, or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The sample tube has an ... 07/06/06 - 20060148009 - Prediction and assessment of immunogenicity A system and method to predict and assess immunogenicity, especially prior to on-set of immunogenic conditions. Also disclosed are methods to identify relevant peptides associated with the formation of antibodies in patients treated with a given protein therapeutic. In various aspects, the present application is directed to methods of determining ... 07/06/06 - 20060148008 - Method of characterizing dendritic cells A method of characterizing cells in a subclass of dendritic cells or precursors thereof in a biological sample. The method comprising placing the sample in contact with immunointeractive molecules directed to at least one dendritic cell immunogen (e.g. HLA-DR, CE123, CD11c, CD1b/c, BDCA2, BDCA3, BDCA4, Cb16, CD83, CD45, CD40, CMRF-44 ... 05/18/06 - 20060105402 - Blood type method system and device A method for the detection and/or visualization of particle agglutination in a particle suspension is provided, comprising placing a volume of the particle suspension and a volume of a solution or suspension containing an agglutinating agent at substantially the same selected location on a surface of a filter constructed so ... 05/11/06 - 20060099656 - Methods and compositions for treating hematological disorders using 232, 2059, 10630, 12848, 13875, 14395, 14618, 17692, 58874, 252, 304, 1980, 14717, 9941, 1941, 19310, or 17832 The present invention relates to methods for the diagnosis and treatment of hematological disorders. Specifically, the present invention identifies the differential expression of 232, 2059, 10630, 12848, 13875, 14395, 14618, 17692, 58874, 252, 304, 1980, 14717, 9941, 19310, or 17832 genes in tissues relating to hematological disorders sensation, relative to ... 05/04/06 - 20060094066 - Myeloperoxidase detection in diagnosis and prognosis of hematopoietic disorders The present invention relates to the diagnosis of hematopoietic disorders and to determining the prognosis of patients affected by such disorders. The methods generally comprise determining a level of myeloperoxidase in a body fluid sample from the individual and using the level as a factor for diagnosing the disorder in ... 04/13/06 - 20060078949 - Flow cytometry based micronucleus assays and kits The invention is a method for analyzing immature reticulocytes for the presence of micronuclei. The method includes reticulocyte enrichment, fluorescent labeling, micronuclei staining, and analysis using single-laser flow cytometry. The invention also includes kits containing reagents to use in the method. ... 03/30/06 - 20060068451 - Dimeric fluorescent polypeptides The invention relates to proteins or polypeptides that comprise intramolecular dimers of fluorescent protein monomers. More specifically, the invention relates to recombinant polypeptides comprising a monomer of a fluorescent polypeptide, a linker peptide, and a second monomer of that fluorescent polypeptide, where the monomers form an intramolecular dimer. The invention ... 03/23/06 - 20060063213 - Method of cancer screening; method of cancer treatment; and method of diabetes treatment A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive administering an needle biopsy; if the result is positive administering a PET scan; if the result is positive administering a blood ... 03/23/06 - 20060063212 - Method of cancer screening; method of cancer treatment; and method of diabetes treatment A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive administering an needle biopsy; if the result is positive administering a PET scan; if the result is positive administering a blood ... 03/23/06 - 20060063211 - Method of cancer screening and method of cancer treatment A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive administering an needle biopsy; if the result is positive administering a PET scan; if the result is positive administering a blood ... 03/16/06 - 20060057648 - Diagnostics and therapeutics for diseases associated with neuromedin u1 receptor (nmu1) The invention provides a human NMU1 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, inflammation diseases, cancer diseases, and disorders of the liver. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological ... 03/02/06 - 20060046276 - Acetyl-ldl receptor as a biomarker for breast cancer The present invention is a biomarker for breast cancer, including early stage and precancerous conditions. Patients exhibiting reduced expression of acetyl-LDL receptor in a NAF sample collected from a breast that is below the 95% confidence limit of normals either have breast cancer are at high risk to develop breast ... 02/16/06 - 20060035290 - Isolation of endothelial progenitor cell subsets and methods for their use A method is provided for the isolation of endothelial progenitor cells from a source of progenitor cells by isolating a population of lineage-negative cells and further isolating CD34+ cells from the lineage-negative population by fluorescence-activated cell sorting. Isolated populations of endothelial progenitor cells and therapeutic compositions containing CD34+ cells for ... 02/16/06 - 20060035289 - Affinity fluorescent proteins and uses thereof The present invention is related to an affinity fluorescent protein (aFP) comprising a modified fluorescent protein or molecule which comprises a heterologous amino acid sequence, thereby introducing a ligand-activated protein binding site, wherein the modified fluorescent protein displays an altered spectral property when the binding site is engaged with ligand ... 02/02/06 - 20060024764 - Proteins producing an altered immunogenic response and methods of making the same The present invention relates to a novel methods and compositions for producing hyper and hypo allergenic compositions. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein. Alternatively, T-cell epitopes are mutated to produce increased ... 01/26/06 - 20060019319 - Methods and apparatuses for conducting assays Disclosed are methods for conducting assays of samples, such as whole blood, that may contain cells or other particulate matter. Also disclosed are systems, devices, equipment, kits and reagents for use in such methods. One advantage of certain disclosed methods and systems is the ability to rapidly measure the concentration ... 11/24/05 - 20050260690 - Methods and materials for diagnosing unstable angina The invention provides methods and materials for diagnosing an angina condition in a patient. Specifically, the invention provides methods and materials for classifying an angina condition as either stable or unstable. In addition, the invention provides methods and materials for determining an individual's predisposition to have a stable or unstable ... 09/29/05 - 20050214877 - Method for monitoring resting and activated platelets in unfixed blood samples The amount of platelet surface proteins in a sample may be measured by collecting a sample containing platelets into a collection tube containing a platelet stabilizing composition, labeling the platelet surface protein and detecting by cytometry. ... 09/22/05 - 20050208599 - Compositions and methods to select dendritic cells from a heterogeneous cell population The present invention is based, at least in part, on methods to select pure and functional dendritic cells from a heterogeneous population of cells. Accordingly, the invention features a method of selecting dendritic cells from a heterogeneous population of cells comprising contacting said cells with an antibody against dendritic cell-specific ... 07/28/05 - 20050164312 - Il1-beta: a new target for myeloma therapy Diagnostic methods for the detection of multiple myeloma (MM) and the identification of high-risk patients with multiple myeloma-related plasma proliferative disorders, such as MGUS or SMM, likely to progress to active MM are described; The diagnosis is based on the determination of concentrations of bioactive IL-1β produced by the bone ... 07/21/05 - 20050158806 - Population based assessments and means to rank the relative immunogenicity of proteins The present invention provides means to assess immune response profiles of populations. In particular, the present invention provides means to qualitatively assess the immune response of human populations wherein the immune response directed against any protein of interest is analyzed. The present invention further provides means to rank proteins based ... 07/21/05 - 20050158805 - Toxicity test An in vitro toxicity assay comprising: a) exposing a spheroid sample to a selected concentration of a compound to be assayed; b) incubating the spheroid sample for a suitable period of time; and c) observing if spheroid cell spreading inhibition takes place. ... 07/07/05 - 20050148033 - Blood compatibility testing method and device The invention relates to a method and device for testing a blood product and a patient's blood immediately prior to transfusing the blood product to the patient. The device comprises a testing chamber within which the blood product and the patient blood are drawn and tested for compatibility. A first ... 06/16/05 - 20050130236 - Method, system, and apparatus for measurement and recording of blood chemistry and other physiological measurements A multi-component test strip for analyzing a plurality of blood components in a single blood sample. The test strip comprises a porous medium having a sample receiving region, and two or more sample analysis regions. The sample receiving region is fluidically in series with the two or more sample analysis ... 06/09/05 - 20050124009 - Determination and quantification of red blood cell populations in samples The invention relates to the detection and determination of erythrocytopathies and hemoglobinopathies. The invention provides a method for distinguishing between subsets of red blood cells in a sample involving contacting the sample with at least a first marker reagent reactive with a first component of a red blood cell and ... 06/02/05 - 20050118654 - Hemoglobin assay for neonatal screening The present invention provides an assay, suitable for neonatal screening of hemoglobinopathies by quantitatively determining the presence of at least one pair of hemoglobin (Hb) variants, determining the ratio between the signals obtained from each variant; and, based on that ratio, determining whether the tested subject is afflicted or not. ... 06/02/05 - 20050118653 - Global test of the hemostatic system This invention demonstrates the feasibility of producing an easy to use, marketable global test in the arena of clinical haemostasis testing that is sensitive to antithrombotic drugs, bleeding disorders and thrombotic pathologies. Use of this assay will provide insight into what predisposes an “apparently” healthy individual to thrombose, what effect ... ### FreshPatents.com Support - Terms & Conditions |