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Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form > Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets) > Coated (e.g., Microcapsules) Coated (e.g., Microcapsules)Coated (e.g., Microcapsules) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.07/12/07 - 20070160678 - Microcapsules with modified release of active principles with low solubility for oral delivery The present invention is directed to microcapsules for reliably modified release and adapted to industrial reproduction of an active principle hardly water-soluble, other than anti-hyperglycemia agents. Each of said microcapsules comprises a core of hardly soluble active principle and a coating film applied on the core. Their mean diameter is ... 07/12/07 - 20070160677 - Encapsulation of lipid-based formulations in enteric polymers A microcapsule comprising a lipid-based core that is encapsulated in an enteric polymer shell providing enhanced bioavailability of a sparingly water-soluble drug as well as modulated release of the drug, wherein the microcapsule is, on one embodiment, prepared by a centrifugal coextrusion process. The lipid-based core comprises lipids carriers, either ... 06/28/07 - 20070148255 - Compositions for delivery of drug combinations Methods to prepare compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents. The compositions exhibit non-antagonistic effects when combinations of drugs are administered. ... 06/28/07 - 20070148254 - Compositions and methods for delivery of proteins and adjuvants encapsulated in microspheres Hydrophobic ion pairing (HIP) is applied to solubilize proteins and/or adjuvants in an organic medium. A polymer is cosolubilized in the medium and microspheres encapsulating the protein and/or adjuvant can be produced by a single emulsion method. Microspheres prepared by this method exhibit low initial burst of the protein and ... 06/21/07 - 20070141165 - Method for manufacturing microcapsules containing capsinoid Capsinoid-containing microcapsules comprising 0.01 to 10 weight parts of capsinoid-containing hydrophobic material per weight part of hydrophilic solution containing 0.001 to 50 percent of capsule wall material and having a median diameter of 0.01 to 1,000 μm are provided. ... 06/21/07 - 20070141164 - Methods and gel compositions for encapsulating living cells and organic molecules A method for encapsulating biologics within a hydrogel by using an aqueous solution of an isocyanate-functional polyurethane prepolymer which is mixed with an amount of biologics and an aqueous solution containing a dithiol crosslinking agent under physiological pH conditions to create a hydrogel. An additional bidentate crosslinking agent is optionally ... 06/21/07 - 20070141163 - Smart bio-nanoparticle elements The invention in suitable embodiments is directed to smart bio-nanoparticle elements and intelligent bio-nanoparticle platforms employing such smart bio-nanoparticle elements. In one aspect, the smart bio-nanoparticle elements are formed with self-assembling protein molecules. ... 06/14/07 - 20070134344 - Antibiotic compositions The invention provides an antibiotic composition comprising coated micropellets and a method for preparing said antibiotic composition. ... 06/07/07 - 20070128291 - Method and apparatus for forming chromonic nanoparticles A method and apparatus for forming guest molecules encapsulated with chromonic material are described. The method includes atomizing a solution to form a pre-atomized particle stream. The solution includes chromonic material, a guest molecule and a carrier fluid. Then, atomizing the pre-atomized particle stream to form an atomized particle stream; ... 05/31/07 - 20070122488 - Multi-functional microcapsules and method and device for manufacturing same Multimicrocapsules that include encapsulated components of at least one nutritionally, pharmacologically, or medically active functional substance, wherein, within an encapsulation of one or more layers of a first encapsulating material around a common capsule matrix, there are provided a first active functional component in an amount sufficient to provide functional ... 05/31/07 - 20070122487 - (poly(acryloyl-hydroxyethyl starch)-plga composition microspheres The present invention relates to a composite microsphere system comprising poly(D,L-lactide-co-glycolide) (PLGA), poly(acryloyl hydroxyethyl starch) (AcHES), and a pharmaceutically effective amount of a biologically active compound. The active compound may be, for example, an insulin, an interferon, a luteinizing hormone-releasing hormone (LHRH) analog, a somatostatin and/or derivatives thereof, a calicitonin, ... 05/24/07 - 20070116777 - Ophthalmic preparation containing menthyl ester of indomethacin There is provided an ophthalmic pharmaceutical preparation comprising menthyl ester of indomethacin as an active ingredient. Also provided are different possible formulations of the ophthalmic preparation, and different methods of treating ophthalmic irritation using the ophthalmic preparation. ... 05/17/07 - 20070110816 - Method of coating nanoparticles Disclosed herein is a method of coating nanoparticles with a metal oxide. The method includes substituting surfaces of hydrophobic nanoparticles with an organic substance having a hydrophilic group effective to render the nanoparticles hydrophilic; and injecting the hydrophilic nanoparticles and a precursor of the metal oxide into an organic solvent ... 05/10/07 - 20070104795 - Multiphase active ingredient formulation The invention relates to a formulation having a plurality of phases containing active ingredients. Said formulation is characterised in that: it contains a first, innermost, finely distributed phase (I) consisting of active ingredients or an active ingredient solution, preferably some of the phase particles being surrounded by a barrier sheath ... 05/03/07 - 20070098807 - Matrices for drug delivery and methods for making and using the same In one aspect, biocompatible matrices such as sol-gels encapsulating a reaction center may be administered to a subject for conversion of prodrugs into biologically active agents. In certain embodiments, the biocompatible matrices of the present invention are sol-gels. In one embodiment, the enzyme L-amino acid decarboxylase is encapsulated and implanted ... 04/05/07 - 20070077309 - Banded controlled release nanoparticle active agent formulation dosage forms and methods Disclosed are controlled release dosage forms and related methods wherein controlled release of self-dispersing nanoparticle active agent formulations is provided by formulating porous particles into which have been sorbed a self-dispersing nanoparticle active agent formulation. ... 04/05/07 - 20070077308 - Continuous multi-microencapsulation process for improving the stability and storage life of biologically active ingredients The present invention relates to microcapsules and a continuous micro-encapsulation water-in-oil-in-water microencapsulation process through in situ and interfacial polymerisation of the emulsion. The formulation comprises a continuous water phase having a dispersion of microcapsules which contain oil drops and wherein the inside of each oil phase drop—containing optionally oil-soluble materials—there ... 03/15/07 - 20070059376 - Peptide conjugate A platelet substitute which does not induce formation of unnecessary thrombi and intravascular coagulation of blood, by causing aggregation of resting platelets in the blood vessel, and has a specific aggregation action is provided. It was found as a result that a peptide conjugate, in which a synthesized form of ... 03/08/07 - 20070053990 - Pharmaceutical formulations exhibiting improved release rates This invention is directed to an apparatus and method for producing microparticles comprising pharmacologically active agents and biodegradable polymers. The apparatus includes a spinning disk containing a reservoir in the center thereof and a flat inclined surface. The apparatus optionally includes serrations and/or a flat surface beneath the periphery of ... 03/01/07 - 20070048385 - Microcapsules by coacervation containing a pharmaceutical incorporated in the coating polymer Microcapsules containing an active ingredient, constituted by a core coated with a polymer membrane, characterized in that the active ingredient is incorporated in the polymer coating layer, and in that said layer is applied using microencapsulation techniques (coacervation by means of phase separation). The microcapsules; thus produced have excellent properties ... 02/08/07 - 20070031505 - Methods for fabricating nano and microparticles for drug delivery The present invention generally relates to stimuli-responsive drug carriers and methods for making. More specifically, the present invention relates to stimuli-responsive lidded particles that respond to a physiological stimulus and dissolve at a target site inside the body thereby releasing therapeutic agents. The present invention further relates to solid, drug-loaded ... 02/08/07 - 20070031504 - Microdevices comprising nanocapsules for controlled delivery of drugs and method of manufacturing same This application relates to a microdevice for delivering drugs to a target location. The microdevice comprises a plurality of nanocapsules assembled together, each having an outer hydrophobic shell and an inner liquid core contained within the shell. At least one drug is dissolved within the inner liquid core. The liquid ... 02/08/07 - 20070031503 - Hyaluronic acid modification products and drug carrier therefrom There is provided a drug carrier which has solved the problems of conventional drug carriers, which can encapsulate a low molecular drug efficiently, which can control a sustained release period for a long term, which can control blood residence, which has high dispersibility in an aqueous solution, and which is ... 02/01/07 - 20070026083 - Method to improve characteristics of spray dried powders and granulated materials, and the products thereby produced A method for preparing solid materials is described. One aspect of the method includes the steps of providing a mixture comprising an organic material in a blend of a solvent and non-solvent for the organic material, distributing the mixture into either droplets or granules, and evaporating the solvent and non-solvent ... 02/01/07 - 20070026082 - Multiparticle pharmaceutical dosage form containing a mucoadhesively formulated peptide or protein active substances method for producing said pharmaceutical dosage form The invention relates to an oral, multiparticle pharmaceutical dosage form containing pellets, the size of which ranges from 50 to 2500 μm and which essentially consist of: a) an inner matrix layer containing an active substance which is a peptide or a protein, including the derivatives or conjugates thereof, and ... 01/25/07 - 20070020339 - Compositions and methods for controlling abuse of medications Pharmaceutical dosage forms are provided for use in deterring abuse of opioids or other medications, which help avoid harm to a patient dependent on the medication. In one case, a pharmaceutical oral dosage form is provided that includes a plurality of microcapsules, each microcapsule of the plurality containing an opioid ... 01/25/07 - 20070020338 - Fluid bed granulation process and apparatus A process for obtaining finished granules of a predetermined substance in a granulation fluid bed (F1) of the so-called vertical growth type, the bed being formed and maintained by a respective flow of fluidification air, comprises a transfer phase by falling of the finished granules in a pressurized space below ... 01/11/07 - 20070009605 - Encapsulation of water soluble peptides This invention relates to a process for preparing biodegradable microspheres and or nanospheres using an oil-in-water process for the controlled release of bioactive peptides. ... 01/04/07 - 20070003631 - Micronetworks, microchannels/cylinders and the process for making the same A micronetwork made from microcapsules with or without nanomaterials and/or micromaterials such as microtubes, nanotubes and/or buckyballs; the micronetworks can be formulated to provide for unique properties such as reduction of crack propagation and/or corrosion. ... 12/07/06 - 20060275376 - Microcapsules with modified release of active principles with low solubility for oral delivery The invention concerns microcapsules for reliably modified release and adapted to industrial reproduction of an active principle hardly water-soluble, other than anti-hyperglycemia agents Each of said microcapsules comprises a core of hardly soluble active principle and a coating film applied on the core. Their mean diameter is less than 1000 ... 11/30/06 - 20060269613 - Composition containing nanoparticles containing water-soluble basic drug encpsulated therein A drug and a biodegradable polymer having at least one carboxyl group are encapsulated into nanoparticle which is formed by a block copolymer having a hydrophilic segment and a hydrophobic segment. This invention thus provides a drug-encapsulated nanoparticle which shows an increased in vivo drug-stability. ... 11/23/06 - 20060263438 - Gelled oil particles for targeting sebaceous glands and/or hair follicles The present invention relates to calibrated and spherical oily particles comprising at least one oily phase structured with at least one gelling polymer, characterized in that they have a mean size of less than or equal to 15 μm, in that the said structured oily phase has a melting point ... 11/23/06 - 20060263437 - Pharmaceutical microspheres containing valproic acid for oral administration The subject of the invention is pharmaceutical microspheres containing, as active principle, a mixture of valproic acid and of one of its pharmaceutically acceptable salts in combination with a matrix vehicle selected from glycerol esters, hydrogenated oils, esterified polyethylene glycols, waxes and their mixtures. ... 11/16/06 - 20060257495 - Method of purification of polyalkylene materials The disclosure provides, in various embodiments, a method of purifying polyalkylene. Also included are microencapsulated Gyricon beads, phase change ink, and toners comprising the purified polyalkylene. ... 11/02/06 - 20060246145 - Methods for treating ocular conditions with cyclic lipid containing microparticles Biocompatible microparticles include an ophthalmically active cyclic lipid component and a biodegradable polymer that is effective, when placed into the subconjunctival space, in facilitating release of the cyclic lipid component into the anterior and posterior segments of an eye for an extended period of time. The cyclic lipid component can ... 11/02/06 - 20060246144 - Microcapsules containing biocide and preparation thereof by solvent evaporation technique The present invention provides polymer microcapsules of biocide, useful for preparing coating materials such as interior and exterior paints, which comprises of an active agent biocide and an encapsulating polymer. Microcapsules described in this invention are prepared by dispersing an organic phase containing an active agent either in dissolved state ... 10/26/06 - 20060240114 - Drug for treating hemophilia and method of treating hemophilia using the same A therapeutic product or drug for therapy of hemophilia may be produced by a simplified method including embedding genes of the blood clotting factors VIII (IX) for therapy of hemophilia in hollow nano particles obtained on expressing the protein having a particle forming function, such as hepatitis B virus surface ... 10/19/06 - 20060233883 - Intravenous nanoparticles for targeting drug delivery and sustained drug release Provided are poly(lactic-co-glycolic acid) (PLGA) and poly(lactic acid) (PLA) nanoparticles that encapsulate a low molecular weight and water-soluble drug and can deliver the drug to target legion sites where the particles gradually release the drug over a prolonged period of time. The nanoparticles are prepared by allowing the low-molecular, water-soluble ... 10/12/06 - 20060228422 - Polysaccharide double-layer microcapsules as carriers for biologically active substance oral administration The present invention relates to microcapsules with a double-layer of natural polysaccharides—chitosan and alginate—gelified and stabilized by means of a divalent ion containing inside at least one biologically active substance. The microcapsules of the invention can be employed as carriers for the oral administration of biologically active substances, also associated ... 09/28/06 - 20060216355 - Encapsulated pharmaceuticals in a medium having non-encapsulated flavoring agents A pharmacologically active ingredient is encapsulated, and in this encapsulated form, is dispersed throughout a pleasantly flavored medium. When the medium is orally ingested, encapsulation of the pharmacologically active ingredient shields the recipient from any associated unpleasant taste, while beneficially providing the pleasant taste of the flavoring of the medium. ... 09/28/06 - 20060216354 - Vector for oral administration A vector for the oral administration of at least one pharmacologically active substance enabling the active substance to move from the intestinal lumen to the blood, optionally via intersticial liquid, without any substantial degradation of the substance, includes an essentially hydrophilic matrix having an outer surface which is modified by ... 09/21/06 - 20060210641 - Absorbable microparticles This invention pertains to a sustained release complex of one or more peptides, one or more proteins or a combination thereof immobilized on an absorbable polymer microparticle optionally having an absorbable polymer coating. The microparticle complex of this invention comprises a peptide(s) and/or protein(s) which have at least one amino ... 09/14/06 - 20060204588 - Formulations of a nanoparticulate finasteride, dutasteride or tamsulosin hydrochloride, and mixtures thereof Described are nanoparticulate compositions of finasteride, dutasteride, tamsulosin hydrochloride, or a combination thereof. The formulations exhibit unexpectedly prolonged release and can be maintained in a depot for release to a patient for a period of up to six months. ... 09/14/06 - 20060204587 - Use of film coating as taste-masking coating of oral dosage forms The present invention relates to the use of a film coating consisting of a) polyvinyl acetate b) hydrophilic additives c) other conventional coating ingredients d) and, where appropriate, a physiologically tolerated acid as taste-masking coating for oral dosage forms, and to a process for producing such dosage forms. ... 09/07/06 - 20060198897 - Polycationic peptide coatings and methods of coating implantable medical devices Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed. ... 08/24/06 - 20060188583 - In situ controlled release drug delivery system A system is described for long-term controlled release delivery of a drug or a therapeutic agent. According to the invention, one or more drugs or therapeutic agents contained in microspheres are mixed with a temperature sensitive hydrogel which is then introduced directly to the desired situs of the drug or ... 08/24/06 - 20060188582 - Double walled microcapsules with an outer thermoplastic wall and application process thereof The present invention concerns double-walled microcapsules with an outer thermoplastic wall and an application process thereof on substrates, namely textile substrate. The microcapsules are applied to fibres so as to produce a slow release of products such as fragrances, antimicrobial, insecticides, antioxidants, vitamins or they can be used as materials ... 08/17/06 - 20060182810 - Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles Sustained-release microparticle composition. The microparticle composition can be formulated to provide multi-phasic release. In one aspect, the composition includes microparticles having more than one rate of release. In another aspect, the composition includes microparticles that exhibit diffusional release and microparticles that exhibit biodegradation release. ... 07/27/06 - 20060165810 - Controlled release from block co-polymer worm micelles Provided is a method of controlling the release of at least one encapsulated active agent from a worm-like micelle, wherein each worm-like micelle comprises one or more amphiphilic block copolymers that self assemble in aqueous solution, without organic solvent or post assembly polymerization; wherein at least one of said amphiphilic ... 07/27/06 - 20060165809 - Oral pharmaceutical formulation in the form of a plurality of microcapsules for prolonged release of active principle(s) with slow solubility The invention concerns microcapsules with prolonged release of active principles with low solubility, consisting of a core containing the active principle and coated with a polymer layer which controls the release of the active principle. The aim is that said oral microcapsules containing hardly soluble active principles should have a ... 07/27/06 - 20060165808 - Microcapsules for the delayed, controlled release of perindopril The present invention relates to A microcapsule composition allowing the delayed and controlled release of perindopril, or of a pharmaceutically acceptable salt thereof, for administration by the oral route. ... 07/27/06 - 20060165807 - Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s) The invention concerns liquid pharmaceutical formulations, for oral delivery, with modified release of active principle(s) excluding amoxicillin and consisting of suspensions of coated particles of active principles (microcapsules). The microcapsules constituting the dispersed phase of the suspension are designed, according to the invention, to enable modified release of the active ... 07/13/06 - 20060153925 - Novel solid pharmaceutical composition comprising amisulpride The invention relates to a solid pharmaceutical composition for oral administration of amisulpride, which comprises at least one coated amisulpride particle and at least one pharmaceutically acceptable excipient suitable for an orodispersible administration of the composition. ... 07/13/06 - 20060153924 - Selection by compartmentalised screening The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, by compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies ... 07/06/06 - 20060147543 - Method for controlling stability of nanofabricated polypeptide multilayer films, coatings, and microcapsules Disclosed herein is a method of controlling the stability of multilayer polypeptide films. A method of controlling the stability of a film, comprises exposing the film to an oxidizing agent or a reducing agent, wherein the film comprises a plurality of layers, the layers comprising alternating oppositely charged polypeptides, wherein ... 07/06/06 - 20060147542 - Solid preparation containing reduced coenzyme q10 and method for producing the same The present invention has its object to provide a solid preparation containing reduced coenzyme Q10 with high stability by protecting reduced coenzyme Q10 against oxidization to oxidized coenzyme Q10 by molecular oxygen. The present invention provides a solid preparation containing reduced coenzyme Q10 which comprises a solid composition containing reduced ... 06/29/06 - 20060141053 - Pharmaceutical composition for improving palatability of drugs and process for preparation thereof The present invention discloses compositions, comprising a lipid-polymer matrix to mask the bitter or unpleasant taste of the medicament. The lipid or a blend of lipids, are used in combination with the pH dependent polymer where the said polymer is acid soluble or swellable The process for the preparation of ... 06/22/06 - 20060134223 - Process for producing microparticles An object of the present invention is to provide a solvent which is able to produce microparticles where content of the drug is still high and no initial burst takes place even when a drug having a low solubility in a halogenated hydrocarbon solvent is used. The present invention provides ... 06/22/06 - 20060134222 - Process for encapsulating an active lipid-soluble substance by preparing a pit emulsion and emulsion obtained The invention relates to a method of encapsulating an active lipid-soluble substance in nanocapsules, by preparing an emulsion. The inventive method is characterised in that it consists in: (a) obtaining an aqueous phase and an oil phase; (b) raising the temperature of the two phases to a temperature greater that ... 06/15/06 - 20060127490 - Liquid core capsules and methods of synthesis thereof through interfacial polymerization A process for the encapsulation of liquid particles within nanometer thick polymer shells utilizes an interfacial free radical alternating copolymerization process. Encapsulating a liquid material includes providing a mixture comprising the liquid material to be encapsulated, a hydrophobic monomer in a non-polar solution and a hydrophilic monomer in a polar ... 06/15/06 - 20060127489 - Targeted delivery An encapsulated product comprises a plurality of micro-capsules formed from a plurality of micro-organisms and having a lipophilic active encapsulated and passively retained within said micro-capsules. The lipophilic active is not being a natural constituent of the micro-organisms, and the micro-capsules has: (a) an at least substantially intact cell wall, ... 06/08/06 - 20060121122 - Process for producing microcapsule A polyelectrolyte solution as a disperse phase is fed into one of the chambers which are partitioned by a plate having a plurality of narrow holes (microchannels), a continuous phase is fed into the other chamber, and pressure is applied to the disperse phase forcing it through the holes into ... 06/08/06 - 20060121121 - Hazard-free microencapsulation for structurally delicate agents, an application of stable aqueous-aqueous emulsion This invention provides method for sustained release delivery of structurally delicate agents such as proteins and peptides. Using unique emulsion system (Stable polymer aqueous-aqueous emulsion), proteins and peptides can be microencapsulated in polysacchride glassy particles under a condition free of any chemical or physical hazard such as organic solvents, strong ... 06/01/06 - 20060115539 - Micropellets method for the production thereof, and use thereof A method for producing micropellets formed of materials that is not easily water soluble, that are provided in the form of a solid dispersion is provided, as well as micropellets which are obtained according to the method, pharmaceutical formulations which contain the micropellets, and the use of micropellets for the ... 06/01/06 - 20060115538 - Calcium lactate and whey permeate for lowering the triglyceride level Disclosed is the combined use of calcium lactate and whey permeate for the prophylaxis or treatment of hypertriglyceridemia and/or symptoms thereof. ... 05/25/06 - 20060110464 - Material encapsulation system A material encapsulation and release system having a first zone (1) containing a first amount of material (2) bound by a first capsule wall (3) and, if desired, a second zone (4) containing a second amount of material (5) bound by a second capsule wall (6), each capsule wall responsive ... 05/25/06 - 20060110463 - Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillin The invention relates to liquid pharmaceutical formulations for oral administration with the modified release of amoxicillin, said formulations consisting of suspensions of coated particles of amoxicillin (microcapsules). According to the invention, the microcapsules constituting the disperse phase of the suspension are designed to allow the modified release of the amoxicillin ... 05/18/06 - 20060105053 - Microsphere filled polymer composites Block copolymers are suitable additives for polymeric composites containing microspheres. The block copolymers have at least one segment that is capable of interacting with the microspheres thereby enhancing the physical characteristics of the composition. ... 05/18/06 - 20060105052 - Cationic nanoparticle having an inorganic core wherein R1independently at each occurrence is an alkoxy group, a hydroxyl group, a halide, an alkyl group, or hydrogen, and wherein at least one R1 of the three R1s is not an alkyl group. A nanocomplex having a cationic nanoparticle and at least one oligonucleotide attached to the cationic nanoparticle ... 05/04/06 - 20060093680 - Coated particles and pharmaceutical dosage forms The present invention relates to coated particles and pharmaceutical dosage forms comprising the active substances sensitive to environmental influences. The coating of the present invention provides stability and protection of the active substance to environmental influences and in particular from oxidation and/or environmental humidity by coating. ... 05/04/06 - 20060093679 - Fast releasing, solid administration form for oral application of active ingredients which are hard to dissolve The present invention is concerned with solid, single-dose dosage forms for an increased rate of release of slightly soluble active ingredients. The dosage forms are based on a coherent matrix which disintegrates rapidly in physiological fluids. The matrix comprises one or more slightly soluble active ingredients in the form of ... 04/27/06 - 20060088599 - Amino functionalized ormosil nanoparticles as delivery vehicles Provided are amino functionalized ORMOSIL nanoparticles. Also provided are compositions comprising such particles and compositions in which the nanoparticles are complexed to polynucleotides. The complexing of polynucleotides to the amino functionalized ORMOSIL nanoparticles protects the polynucleotides from environmental damage. These complexes can be used for delivery of polynucleotides to cells. ... 04/27/06 - 20060088598 - Intravenous composition, process for producing the same and preparation thereof A composition for intravenous injection, which gradually decomposed instead of fat particles, has sufficient sustained release effects, has an excellent encapsulation ratio of lipid-soluble agents, and has such sustained release effects at lesion sites; a production method thereof; and a preparation containing the composition. The composition for intravenous injection is ... 03/30/06 - 20060068021 - Sustained-release microencapsulated delivery system Disclosed is a process for producing sustained-release powders that is fast, efficient, and economical. The process involves melting a naturally derived oil with a melting point above 110° F. in specially designed mixer through either the work energy input of the mixer shaft itself, or a specially fitted plow type ... 03/30/06 - 20060068020 - Encapsulated pharmaceutical agents The present invention provides stable lipid-based pharmaceutical formulations containing ivermectin, praziquantel and pyrantel pamoate, and methods for preparing the formulations. Further provided is a method of treating helminthiasis of mammals, which comprises administering a pharmaceutical composition that is highly effective against helminths, particularly tapeworm, hookworm, roundworm and heartworm of domestic ... 03/30/06 - 20060068019 - Coated polyunsaturated fatty acid-containing particles and coated liquid pharmaceutical-containing particles A process for coating a polyunsaturated fatty acid (PUFA)-containing carrier particle or a PUFA matrix particle, or a liquid pharmaceutical-containing carrier particle or a liquid pharmaceutical matrix particle. Also disclosed are such particles made by the process of the invention and foods, pharmaceuticals, beverages, nutritional supplements, infant formula, pet food ... 03/23/06 - 20060062855 - Therapeutic calcium phosphate particles for use in inhibiting expression of a gene Novel calcium phosphate core particles, methods of making them, and methods of using them as carriers of biologically active material and controlled release matrices for biologically active material are disclosed. The core particles may have a surface modifying agent and/or biologically active material, such as polynucleotide material partially coating the ... 03/16/06 - 20060057222 - Method for the production of polymerized nanoparticles and microparticles by ternary agent concentration and temperature alteration induced immiscibility Polymerized drug delivery devices are described. Additionally, methods are described for producing and for using polymerized particles for use as drug delivery devices. ... 03/16/06 - 20060057221 - Polymeric microparticulates for sustained release of drug and their preparation methods The present invention relates to polymeric microparticulates for sustained release of drug and to the process for the preparation thereof. The process of the present invention for preparing polymeric microparticulates based on microcoagulation phenomenon of water-soluble polymer not only improves loading amount of drug but also minimizes initial burst of ... 03/16/06 - 20060057220 - Fine spherical particles with satisfactory molecular orientation, spherical microcapsules comprising the same and processes for producing these The present invention relates to a fine spherical particle having uniform molecular orientation having uniform molecular orientation, which is useful in fine chemical fields or electronic and information fields, such as a functional material and a medical material, using membrane formation of a bicephalic compound; a spherical microcapsule encapsulating a ... 03/16/06 - 20060057219 - Method for preparing a polymer micelle pharmaceutical preparation containing drug for injection A production method of a preparation containing drug-encapsulating polymer micelles is provided, which comprises dissolving a hydrophilic-hydrophobic block copolymer and a sparingly water-soluble drug in a volatile organic solvent, then removing the solvent, and stirring the residue with water at a temperature not higher than 30° C. to dissolve the ... 03/09/06 - 20060051425 - Method of microencapsulation The present invention provides methods for microencapsulation of active ingredients for topical application, whereby single-layer and multi-layer, preferably double-layer, microcapsules, are obtained. The microcapsules protect the active ingredients, maintain their original activity throught processing, formulation and storage, and enable controlled release of the active ingredient only upon application onto the ... 03/09/06 - 20060051424 - Compositions of oral gene therapy and methods of using same The present invention provides nanoparticle compositions comprising a cationic biopolymer and at least one biologically active substance, pharmaceutical compositions comprising such nanoparticles and methods for the oral administration of biologically active molecules which are susceptible to degradation in the gastro-intestinal tract using nanoparticle. The present invention further provides compositions and ... 02/16/06 - 20060034936 - Sensate compositions and delivery systems therefor The present invention includes compositions for imparting a controlled-release sensation to the oral receptor areas of a user. The oral, controlled-release compositions include a sensate and a hydrated or swollen food-grade polymer which forms a matrix with the sensate. Sensates may include warming, cooling and/or tingling agents. Also included are ... 02/02/06 - 20060024379 - Protein microspheres having injectable properties at high concentrations The present invention relates to compositions of methods of making and compositions small compositions of particles of an active agent. In accordance with the method of production, the active agent is dissolved in an aqueous or aqueous-miscible solvent containing a dissolved phase-separation enhancing agent (PSEA) to form a solution in ... 01/19/06 - 20060013887 - Delayed release carnitine A sustained release, orally administered pharmaceutical composition comprising carnitine and an acceptable pharmaceutical excipient is described for the treatment of carnitine deficiency and other carnitine responsive conditions. The sustained release formulation avoids the characteristic problems of gastrointestinal invitation, dumping in the urine and bacterial degradation attendant previously known oral formulations ... 01/05/06 - 20060003014 - Safe delivery system for agriculturally active material A safe delivery system of agriculturally active material is formed using an encapsulation process. A microencapsulated suspension of agriculturally active material includes an encapsulating agent formed from a graft copolymer of starch and at least one vinyl monomer. ... 12/29/05 - 20050287221 - Method and apparatus for encapsulating pharmaceutical and nutriceutical bioactives for intestinal delivery A method for the encapsulation and subsequent delivery of a biologically, water or lipid soluble, active agent to the human intestinal mucosa. This biochemical pathway to drug delivery includes the steps of forming an aqueous emulsion of the pharmacological or nutriceutical agent, vegetable oil, gum and/or gum resin, absorbent factors, ... 12/22/05 - 20050281886 - Particles for the delivery of active agents Particles of less than 100 microns, where an active agent is coated with a matrix of cationic and anionic polymers, are efficient vehicles for delivering active agents to tissues such as skin and mucosal membranes. Such particles are able to deliver compounds to skin with little associated irritation. Prior art ... 12/22/05 - 20050281885 - Method for treating inflammatory bowel disease by oral administration of il-10 The present invention provides compositions and methods for reducing the severity of inflammatory bowel disease. The composition comprises polymeric microspheres encapsulating IL-10. These polymeric microspheres can be administered orally to individuals to treat inflammatory bowel disease. ... 12/15/05 - 20050276862 - Iron sequestering antimicrobial composition This invention relates to a composition of matter comprising an immobilized metal-ion sequestrant/antimicrobial comprising a metal-ion sequestrant that has a high stability constant for a target metal ion and that has attached thereto an antimicrobial metal-ion, wherein the stability constant of the metal-ion sequestrant for the antimicrobial metal-ion is less ... 12/08/05 - 20050271737 - Application of a bioactive agent to a substrate A selected morphology for a deposited bioactive agent may be obtained by selecting a target particle morphology, preparing a solution of the bioactive agent, and applying the bioactive agent solution to a substrate as a plurality of droplets so that evaporation of the solution produces particles having the target morphology. ... 12/08/05 - 20050271736 - Pyrithione compound and microcapsule using the same wherein, in formula (II), R3 represents an arbitrary m-valent linking group; and m represents an integer of 2 or above. ... 12/08/05 - 20050271735 - Method of encapsulating hydrophobic organic molecules in polyurea capsules It is known to encapsulate various materials in polyurea microcapsules, but obtaining satisfactory microcapsules incorporating alcoholic materials has proven difficult. A process has now been found where polyurea microcapsules are formed by interfacial polymerization between an aqueous phase and a water-immiscible phase, and properties, particularly the solubility parameters, of the ... 12/01/05 - 20050266092 - Loaded microspheres The invention relates to loaded microspheres with a mean diameter of 0.001 to 1 mm, and loaded with one or more absorbed or adsorbed active principles, which are obtained by mixing fine-particle polymethyl methacrylate or methyl methacrylate cross polymer with lipophilic or hydrophilic active principles until they have been absorbed ... 11/24/05 - 20050260275 - Encapsulated peptide copper complexes and compositions and methods related thereto This invention relates to compositions comprising encapsulated peptide copper complexes, and, additionally, to such compositions formulated for use as pharmaceutical and cosmetic products, as well as to medical devices that comprise such compositions. ... 11/17/05 - 20050255165 - Compositions and methods for biodegradable microspheres as carriers of bioactive substances A cost-effective, scalable technique for producing microspheres loaded with biologically active solid proteins is provided. The microspheres degrade over time and release biologically active VEGF, as demonstrated by the proliferation of HUVECs in vitro compared to negative controls. A defined concentration of microspheres can deliver a quantifiable level of VEGF ... 10/20/05 - 20050233003 - Hydrophilic dispersions of nanoparticles of inclusion complexes of salicylic acid The invention provides a hydrophilic inclusion complex consisting essentially of nanosized particles of salicylic acid wrapped in an amphiphilic polymer, wherein said amphiphilic polymer is selected from the group consisting of polyacrylic acid, polyacrylamide and copolymers thereof, polymethacrylamide and copolymers thereof, and polylysine, and said amphiphilic polymer is modified by ... 10/20/05 - 20050233002 - Encapsulation of oxygen sensitive agents The present invention relates to the use of a mixture of modified starch and protein for encapsulating oxygen sensitive agents, wherein the modified starch is a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group which has been further enzymatically hydrolyzed by an exo-enzyme. The ... 10/06/05 - 20050220891 - Multi-layer cell encapsulation for tissue engineering A multi-layered microcapsule has an inner extracellular matrix and an outer shell. The inner extracellular matrix includes a first inner layer of biopolymer and a second intermediate layer of polymer that provides partial immune-protection and holds the first layer in place. The outer shell can form an exoskeleton to provide ... 10/06/05 - 20050220890 - Ion binding compositions The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, ... 10/06/05 - 20050220889 - Ion binding compositions The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, ... 10/06/05 - 20050220888 - Controlled release compositions and methods for using same Pharmaceutical preparations adapted for mucosal delivery, preferably for nasal delivery, which can be easily and safely used over days to weeks with minimal side effects. The pharmaceutical preparations comprise microcapsules comprising at least one pharmaceutically active agent. The microcapsules provide controlled release of the pharmaceutically active agent. Cytotoxicity is avoided ... 09/29/05 - 20050214380 - Nanobioprocessor for protein and cell therapy A nanobioprocessor for protein and cell therapy comprises a selectively coated quantum dot having selected band gap energies, characteristic absorption, emission spectra and outer coatings for therapy and diagnostic purposes in biophotonics and nanomedicine, and an electromagnetic radiation and detector source configured to remotely heat and/or selectively excite the quantum ... 09/29/05 - 20050214379 - Encapsulation of chemical compounds in fluorous-core and fluorous-inner-shell micelles formed from semifluorinated-block or fluorinated-block copolymers In one embodiment of the present invention, a block copolymer with a hydrophilic region and a semifluorinated region is synthesized and mixed, below a critical micellar concentration, with a fluorinated drug, and the temperature then lowered, or the block-copolymer concentration then increased, or other solution conditions changed, in order to ... 09/29/05 - 20050214378 - Stealth lipid nanocapsules, methods for the preparation thereof and use thereof as a carrier for active principle(s) The present invention relates to stealth lipid nanocapsules comprising an essentially lipid core which is liquid or semi-liquid at ambient temperature, and an outer lipid envelope comprising at least one hydrophilic surfactant which is lipidic in nature, at least one lipophilic surfactant which is lipidic in nature and at least ... 09/22/05 - 20050208146 - Novel dosage and administration method for oral camptosar The present invention relates to a maximally tolerable dosage of oral irinotecan encapsulated in a semi-solid filling medium which comprises the irinotecan or a derivative thereof; a pharmaceutically acceptable carrier matrix which is a polyglycolized glyceride; and an effective thickening-reducing and stabilizing-promoting amount of one or more pharmaceutically acceptable excipients, ... 09/22/05 - 20050208145 - Grain fiber compositions and methods of use The present invention relates to beta-glucan compositions having a honeycomb structure and the uses of the compositions as encapsulating agents. ... 09/22/05 - 20050208144 - Microcapsule suspension liquid and process for production thereof An aqueous microcapsule suspension liquid exhibiting an excellent (long-term) storage stability and allowing easy re-dispersion and dilution with water even after such a storage, is produced by adding a microorganism-fermented polysaccharide of succinoglycan type as a thickening agent into a microcapsule slurry, or by adding such a microorganism- fermented polysaccharide ... 09/15/05 - 20050202096 - Microcapsules for encapsulation of bioactive substances The invention relates to photo-crosslinkable microcapsules with enhanced properties for encapsulation of bioactive substances. The present invention also relates to a microencapsulation composition and to a method of manufacturing microcapsules. The microcapsule comprise bioactive substances that are encapsulated by a selectively permeable polymeric membrane. The selectively permeable membrane is impermeable ... 09/08/05 - 20050196459 - Odor absorbing pad for shoes The field of the invention is that of oral pharmaceutical medicinal products or compositions, more particularly of the type of those comprising one or more active principles. The aim of the invention is to provide an improved oral medicinal product that can be administered in one or more daily doses, ... 09/01/05 - 20050191362 - Method of preparing microcapsules encapsulating a phase transition material A phase transition material, an acrylic monomer and a free-radical initiator are dissolved in an organic solvent to form an oil-phase solution. The acrylic monomer, having bi-functional and/or tri-functional groups, undergoes free radical polymerization to form the microcapsules shells encapsulating the phase transition material. A surfactant is dissolved in water ... 08/18/05 - 20050181063 - Pharmaceutical composition for administration to mucosal surfaces A pharmaceutical composition for administration to mucosal surfaces, which composition comprises a biologically active agent, a first amount of said agent being encapsulated within microspheres which comprise a polymer which has a molecular weight in excess of 94 kDa and a maximum diameter of 20 μm, and a second amount ... 08/04/05 - 20050170005 - Methods for encapsulating small spherical particles prepared by controlled phase separation The present invention relates to methods of making and compositions of microencapsulated small particles of an active agent. In accordance with the method of production, the active agent is dissolved in an aqueous or aqueous-miscible solvent containing a dissolved phase-separation enhancing agent (PSEA) to form a solution in a single ... 08/04/05 - 20050170004 - Nanoparticles for drug delivery A pharmaceutical composition comprising a nanoparticle and any one of a peptide, a polysaccharide, or a glycoprotein, attached electrostatically thereto, and a pharmaceutically acceptable carrier. Uses of the composition and processes for its preparation. ... 07/21/05 - 20050158396 - Antioxidative preparations An antioxidative composition containing: (a) an active component selected from the group consisting of (i) at least two extracts selected from the group consisting of Vaccinium myrtillus, Trifolium pratense, Vitis vinifera and Thea vinensis; (ii) at least two active components selected from the group consisting of anthocyanosides, isoflavone glucosides and ... 07/21/05 - 20050158395 - Device and method for producing a cross-linked substance, especially in the form of a microcapsule or layer A device for producing a crosslinked substance, e.g., of crosslinked microcapsules (1) of a crosslinkable capsule substance, in particular crosslinked alginates, is described, having a first dispensing device (2) for dispensing a jet of the crosslinkable capsule substance and a crosslinking device for applying a crosslinking agent to the capsule ... 07/07/05 - 20050147689 - Method for inhibiting the growth of gastrointestinal tract tumors The present invention provides compositions and methods for preventing the development of or reducing the growth of gastrointestinal tumors. The composition comprises polymeric microspheres encapsulating sulindac, IL-12 or both. These polymeric microspheres can be administered orally to individuals to reduce the growth of or prevent the development of gastrointestinal tumors. ... 06/30/05 - 20050142207 - Method for preparing polymeric microsphere by aqueous two phase emulsion process A method for preparing polymeric microsphere by an aqueous two phase emulsion process. A first polymer aqueous solution is provided and the first polymer includes a functional group capable of forming cross-linking. A second polymer aqueous solution is provided, which is acidic and miscible with the first polymer aqueous solution. ... 06/30/05 - 20050142206 - Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation The present invention is related to a method for preparing small spherical particles of an active agent by providing a solution in a single liquid phase. The single liquid phase comprises an active agent, a phase separation enhancing agent, and a first solvent. A phase change is induced at a ... 06/30/05 - 20050142205 - Methods for encapsulating small spherical particles prepared by controlled phase separation The present invention relates to methods of making and compositions of microencapsulated small particles of an active agent. In accordance with the method of production, the active agent is dissolved in an aqueous or aqueous-miscible solvent containing a dissolved phase-separation enhancing agent (PSEA) to form a solution in a single ... 06/30/05 - 20050142204 - Triclosan dosage form This invention relates to triclosan and more particularly to a dosage form of triclosan especially for use in the treatment, including prophylaxis, of malaria. This invention further relates to use of a triclosan emulsion or oil solution in the preparation of a composition for use in the treatment, including prophylaxis, ... 06/23/05 - 20050136121 - Oral peptide delivery system with improved bioavailability An oral peptide delivery system where the peptide is present in a solid lipid suspension, wherein the suspension exhibits pseudotropic and/or thixotropic flow properties when melted, and in a preferred embodiment, the peptide is insulin, where the delivery system provides an improved bioavailability of the peptide. ... 06/16/05 - 20050129778 - Pharmaceutical composition containing water soluble drug The present invention is directed to a process of preparing beads coated with a water soluble drug for incorporation into a pharmaceutical composition comprising: (a) preparing a supersaturated drug solution containing a desired amount of drug, which is completely saturated at a first temperature but which is supersaturated at a ... 06/16/05 - 20050129777 - Elemental nanoparticles of substantially water insoluble materials This invention relates to a novel process of manufacture of nanoparticles of substantially water insoluble materials from emulsions. The emulsions have the ability to form a single liquid phase upon dilution of the external phase, instantly producing dispersible solid nanoparticles. The formed nanoparticles have average diameter of about 10 to ... 06/09/05 - 20050123618 - Method of producing micro-capsules for the sustained release of drugs Micro-capsules for the slow release of drugs, consisting of a lactic-co-glycolic copolymer to which a plasticiser has been incorporated and which contain a drug of pharmaceutical interested within them. ... 06/09/05 - 20050123617 - Biodegradable polymeric nanocapsules and uses thereof The present invention relates to a biodegradable polymeric nanocapsule composition, adaptable for encapsulation of an agent of therapeutic interest for enhancing the in vivo circulation time of thereof and uses thereof. ... 06/02/05 - 20050118276 - Coated metal pyrithione particles for treatment of microorganisms A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care ... 06/02/05 - 20050118275 - Immunogenic compositions containing microparticles comprising adsorbed toxoid and polysaccharide-containing antigens Immunogenic compositions comprising microparticles with adsorbed toxoid antigen and/or polysaccharide-containing antigen are disclosed. The immunogenic microparticle compositions comprise (a) polymer microparticles comprising a biodegradable polymer; (b) an antigen adsorbed to the microparticles selected from (i) a toxoid antigen, such as a tetanus toxoid, a diphtheria toxoid, or a combination thereof, ... 06/02/05 - 20050118274 - Method and device for feeding living cells into a biological body fluid Disclosed is a method for feeding living cells into a body fluid, particularly into a blood stream, according to which one or several of the cells are combined into capsule units by an enveloping substance surrounding the cells. In order to prevent coagulation or rejection, coagulation-inhibiting agent or coagulation-preventing structures ... 06/02/05 - 20050118273 - Microcapsules and oral composition containing the same The present invention provides microcapsules with favorable speed, intensity and persistence of the release of foreign substances encapsulated inside microorganism cells. The present invention also provides a manufacturing method of a microcapsule and an oral composition containing the microcapsule. The microcapsules having at least one foreign substance enclosed in microorganism ... ### FreshPatents.com Support |