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Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets)

Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets) patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

Related Categories:

Drug, Bio-affecting And Body Treating Compositions


Preparations Characterized By Special Physical Form > Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets)



Composition and methods for enhancing surface reflectance
03/26/15 - 20150086630 - Microspheres, typically sterile, inert, silica glass microspheres, are dispersed in a carrier suitable for use relative to the object to be imaged and analyzed. In the case of ophthalmic imaging, an ophthalmically-acceptable gel is used and the resulting composition is dispensed into a mammalian eye. The gel and microspheres dispersed...

Multi-functional micro and nanoparticles for use in root canal therapies
03/26/15 - 20150086631 - Chitosan nanoparticles are provided for use in the in vivo treatment of connective tissues in root canal therapies. The nanoparticles are optionally linked with one or more photoactivatable compounds for providing antibactenal/antibiofilm properties, neutralizing bacterial byproducts and/or chemical/photodynamic crosslinking to achieve enhanced mechanical properties, chemical stability in connective tissues and/or...

Injectable formulation
03/26/15 - 20150086632 - An object of the present invention is to provide a sustained-release injectable preparation which is in a medication administration form that can provide the effect of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one for a prolonged period of time, the preparation releasing a therapeutically effective amount of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one for at least one week. The present invention...

Surface modified inorganic oxide fine particles, and sunscreen cosmetic material containing same
03/26/15 - 20150086633 - The surface-modified inorganic oxide fine particles include inorganic oxide fine particles having an average particle size of 200 nm or less; and a group containing a polyglycerol chain and modifying surfaces of the particles. The inorganic oxide is preferably selected from titanium oxides, silicon oxides, aluminum oxides, zirconium oxide, and...

Cosmetic uses of molded placental compositions
03/26/15 - 20150086634 - Described herein are methods of using molded dehydrated placental compositions, and cosmetic compositions thereof. The compositions have numerous cosmetic applications....

Nanoparticulate megestrol formulations
03/26/15 - 20150086635 - The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm....

Myostatin inhibition for enhancing muscle and/or improving muscle function
03/26/15 - 20150086636 - The present invention relates to methods for inhibiting myostatin, a regulator of muscle mass, for muscle enhancement (including inducing hypertrophy and/or hyperplasia) as well as improving muscle function (including decreasing atrophy and/or increasing endurance, force and/or strength). Some of the methods involve delivering genes to cells using gene delivery or...

Novel composition for treatment of essential thrombocythemia
03/26/15 - 20150086637 - The present invention relates to a novel pharmaceutical composition free of gastric coating comprising anagrelide hydrochloride in combination with a non-pH dependent polymer and a pharmaceutically acceptable watersoluble acid and its use for the treatment of essential thrombocythemia....

Aqueous parasiticidal suspension
03/26/15 - 20150086638 - Aqueous parasiticidal suspension typically comprising from 1 to 15% by weight of silica and from 30 to 45% by weight of sodium bicarbonate and method for controlling the development of parasites on animals raised in buildings, according to which the environment of the animal in the building is brought into...

Tumor vaccine and method for producing the same
03/26/15 - 20150086639 - The invention provides a tumor vaccine and method for producing the same. The tumor vaccine comprises cell vesicles derived from apoptotic tumor cells and an adjuvant. The invention further provides a preparation method of the tumor vaccine, comprising the steps of using the UV to irradiate the tumor cells to...

Formulations decreasing particle exhalation
03/19/15 - 20150079173 - Formulations have been developed for pulmonary delivery to treat or reduce the infectivity of diseases such as viral infections, especially tuberculosis, SARS, influenza and respiratory synticial virus in humans and hoof and mouth disease in animals, or to reduce the symptoms of allergy or other pulmonary disease. Formulations for pulmonary...

Antimicrobial complexes
03/19/15 - 20150079174 - The invention relates to an antimicrobial surfactant complexed with a nanomaterial. The surfactant can be a quaternary ammonium cationic surfactant which is coated on the surface of a nanomaterial such as a silica nanoparticle or a carbon nanotube....

Topical pharmaceutical composition, method for producing the topical pharmaceutical composition, use of the topical pharmaceutical composition and method for the topical treatment of psoriasis, atopic dermatitis or chronic eczema
03/19/15 - 20150079175 - This invention relates to a topical pharmaceutical composition comprising a combination of methotrexate, alpha bisabolol and allantoin; a process for producing the same and the use of the composition in the treatment of plaque psoriasis (psoriasis vulgaris), atopic dermatitis and chronic eczema. The composition of this invention can be used...

Anti-oxidant synergy formulation nanoemulsions to treat cancer
03/19/15 - 20150079176 - A uniform microfluidized nanoemulsion is disclosed containing a synergistic combination of two antioxidants and a cell membrane stabilizer phospholipid (i.e., an anti-oxidant synergy formulation; ASF). The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of typically...

Methods and compositions for treating proliferative diseases
03/19/15 - 20150079177 - The present invention provides combination therapy methods of treating proliferative diseases (such as cancer) comprising a first therapy comprising administering to an individual an effective amount of a taxane in a nanoparticle composition, and a second therapy which may include, for example, radiation, surgery, administration of chemotherapeutic agents, or combinations...

Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
03/19/15 - 20150079178 - The present invention relates to a stable fixed dose aqueous pharmaceutical composition (e.g., contained in a container) for nasal administration to a human, comprising mometasone or its salt, olopatadine or its salt. The composition may further include a hydrocolloid. The invention also relates to a process for preparing the pharmaceutical...

Sustained release formulations of peptidomimetic drugs and uses thereof
03/19/15 - 20150079179 - The invention provides sustained release formulations comprising a C5a receptor antagonist. In certain embodiments the sustained-release formulations include microparticles that comprise a complement C5aR antagonist and a biodegradable polymeric matrix. Methods of treatment comprising the sustained release formulations of the invention are also provided....

Nanoparticle compositions of dimethyl fumarate
03/19/15 - 20150079180 - Disclosed herein are compositions of dimethyl fumarate exhibiting reduced gastrointestinal irritation and related side effects....

Methods and compositions for treating recurrent cancer
03/19/15 - 20150079181 - The present invention provides methods of treating recurrent cancer (such as recurrent ovarian, peritoneal, or fallopian tube cancer) in an individual, comprising administering to the individual an effective amount of a composition (such as Nab-paclitaxel or Abraxane®) comprising nanoparticles comprising a taxane and a carrier protein....

Pharmaceutical compositions comprising silica microspheres
03/19/15 - 20150079182 - A topical composition which includes a silica microspheres and an active ingredient in the amount of 0.01 to 15.0% w/w wherein the active ingredient is selected from adapalene, an antibiotic, tazarotene, tretinoin, a retinoid, or any combination thereof. The topical composition may also include benzoyl peroxide as an active ingredient....

Mesoporous silica compositions for modulating immune responses
03/12/15 - 20150072009 - A composition comprising mesoporous silica rods comprising an immune cell recruitment compound and an immune cell activation compound, and optionally comprising an antigen such as a tumor lysate. The composition is used to elicit an immune response to a vaccine antigen....

Combination of azelastine and mometasone for nasal administration
03/12/15 - 20150072010 - A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutical acceptable salt, solvate or physiologically functional derivative thereof, preferably the product or formulation being in a form suitable for nasal or ocular administration....

Carboxylvinyl polymer-containing nanoparticle suspensions
03/12/15 - 20150072011 - The present invention generally relates to suspension compositions having a carboxyvinyl polymer such as a carbomer, a galactomannan such as guar, and a borate compound. A sparingly soluble particulate compound such as nepafenac is also included in the compositions. The sparingly soluble particulate compound has a small particle size to...

Novel highly bioavailable, water soluble and sustained release nanoformulations hydrophobic plant derived compounds and extracts
03/12/15 - 20150072012 - A highly bioavailable, water soluble, sustained release nanoformulation comprising a hydrophobic plant derived compound(s) in an emulsifier phase, and aqueous phase. The formulation provides sustained release of the hydrophobic plant derived compound(s) over a 24 hr time period. A process for preparation of the water soluble nanoformulation is described....

Intra-articularly supplementation method for treating joint diseases and injuries
03/12/15 - 20150072013 - isolating polymerised beads from the solution with cations....

Method for treatment of pain and inflammation
03/05/15 - 20150064254 - The present invention relates to a method for the treatment of pain and inflammation. In particular, the present invention relates to a method for the treatment of musculo-skeletal and connective tissue pain/inflammations. Further, the invention relates to reducing the incidence and seventy of adverse events resulting from administration of diclofenac....

Nanostructures for treating cancers and other conditions
03/05/15 - 20150064255 - Nanostructures, compositions and methods for treating cancers and other conditions are provided. In some cases, the nanostructures and/or compositions may be used to treat cancers or other diseases or conditions at least in part by controlling cholesterol metabolism in cells. The nanostructures and compositions may be used, for example, to...

Porous carbon particles for use in the treatment or prevention of liver disease
03/05/15 - 20150064256 - The invention provides porous carbon particles for use in the treatment or prevention of liver disease, wherein at least 20% of the total pore volume is made up of pores having a mean diameter of from 2 to 200 nm and/or wherein the particles comprise micropores of diameter 2 nm...

Metalaxyl and prothioconazole cocrystals and methods of making and using
03/05/15 - 20150064257 - The invention relates to co-crystals of metalaxyl and prothioconazole, to methods of making them, to compositions containing them and to the methods of using said co-crystals and said compositions to treat crops and plants....

Diclofenac formulations and methods of use
03/05/15 - 20150064258 - Methods and formulations are provided for treating migraine and other acute pain episodes using diclofenac, and formulations of diclofenac that provide both rapid and sustained relief from acute pain. Methods and formulations are also provided for treating symptoms that often accompany migraine and acute pain such as photophobia, phonophobia, nausea...

Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
03/05/15 - 20150064259 - A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of...

Collagen production enhancer
03/05/15 - 20150064260 - A collagen production enhancer for increasing the amount of collagen contained in the skin tissues, comprising calcium phosphate fine particles as effective ingredients....

Electrophoretically deposited strontium fluoride nanoparticle/polymer coatings for medical implants
02/26/15 - 20150056282 - The present disclosure provides for co-electrophoretic deposition (co-EPD) of organo-functionalized strontium fluoride nanoparticles (SrF2) with a hydrophobic polymer in the presence of non-aqueous aprotic solvents. The co-EPD procedure can be employed to form a coating or self-supporting film for application to a metal implant....

Methods of using cerium oxide nanoparticles to mitigate or protect against radiation injury
02/26/15 - 20150056283 - Methods of mitigating the effects of radiation exposure or providing a radioprotective effect in a subject are provided herein. The methods include administering a therapeutically effective amount of cerium oxide nanoparticles to the subject to mitigate the effects of radiation exposure or to offer a radioprotective effect to the subject....

Pharmaceutical composition
02/26/15 - 20150056284 - A preparation for oral administration comprising: a pregelatinized starch comprising N-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]-(2R,3R)-2,3-tetramethylene-butyl]-(1′R,2′S,3′R,4′S)-2,3-bicyclo[2,2,1]-heptanedicarboxyimide hydrochloride (lurasidone) represented by the formula (1) as an active ingredient; a water-soluble excipient; and a water-soluble polymeric binder, the preparation exhibiting an invariant level of elution behavior even when the content of its active ingredient is varied....

Sustained release formulations using non-aqueous carriers
02/26/15 - 20150056285 - The disclosure provides one-component, injectable, sustained release formulations which comprise microspheres containing active pharmaceutical ingredients (e.g., exenatide), wherein the microspheres are suspended in a non-aqueous carrier. The non-aqueous carrier can be an oil, a fractionated oil, triglycerides, diglycerides, monoglycerides, propylene glycol fatty acid diesters, and the like. The formulations offer...

Nanoparticulate megestrol formulations
02/26/15 - 20150056286 - The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm....

Nanoparticulate megestrol formulations
02/26/15 - 20150056287 - The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm....

Compositions for treatment of skin disorders
02/19/15 - 20150050342 - Compositions are provided comprising: (i) chlorhexidine or a pharmaceutically acceptable salt thereof; (ii) niacinamide or niacin; and (iii) salicylic acid or a pharmaceutically acceptable salt or derivative thereof. The compositions are suitable for use in treating and preventing disorders of the skin. The compositions are also provided in the form...

Methods of wound care and treatment
02/19/15 - 20150050343 - Provided are electrokinetically-altered fluids (e.g., gas-enriched electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for use in treating a wound to a surface...

Compositions and methods for upregulating hippocampal plasticity and hippocampus-dependent learning and memory
02/19/15 - 20150050344 - Provided are methods for enhancing hippocampal plasticity and hippocampal-mediated learning and memory, and/or enhancing the synaptic maturation of neurons, and/or optimizing or enhancing neuronal synaptic transmission, and/or enhancing intracellular oxygen delivery or utilization, and/or enhancing ATP synthesis, comprising administration, to a subject in need thereof of a sufficient amount over...

Methods for fine particle manufacture
02/19/15 - 20150050345 - Processes for preparing micronized particles comprising a poorly water soluble bioactive agent are provided. The processes utilize a superheated aqueous phase which can serve as the continuous phase of an emulsion. The superheated aqueous phase can be used to melt poorly water soluble bioactive agents and/or matrix materials which them...

Compositions and methods for treating insulin resistance and diabetes mellitus
02/19/15 - 20150050346 - Provided are electrokinetically-altered fluids (gas-enriched electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for use in treating diabetes and diabetes-associated conditions or disorders...

Reverse micelle system comprising nucleic acids and use thereof
02/19/15 - 20150050347 - The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical...

Aerosol tyrosine kinase inhibitor compounds and uses thereof
02/12/15 - 20150044288 - Disclosed herein are formulations of imatinib or a phenylaminopyrimidine derivative compound for aerosolization and use of such formulations for inhaled aerosol administration of imatinib or a phenylaminopyrimidine derivative compound for the prevention or treatment of various fibrotic, carcinogenic, vascular and viral infectious diseases, including diseases associated with the lung, heart,...

Hypromellose acetate succinate for use as hot-melt extrusion carrier, hot-melt extrusion composition, and method for producing hot-melt extrudate
02/12/15 - 20150044289 - Provided are hypromellose acetate succinates (HPMCAS) for use as a hot-melt extrusion carrier having a volume average particle size (D50) of from 70 to 300 as measured by dry laser diffraction and a loose bulk density of from 0.25 to 0.40 g/cm3; and a hot-melt extrusion composition comprising the HPMCAS...

Treatment method using liquid food composition
02/12/15 - 20150044290 - Provided is a liquid food composition capable of semi-solidifying in the stomach, which is a one-pack type product containing a water-soluble dietary fiber preliminarily added thereto and in the form of a liquid that can be easily taken, and stably sustains the liquid nature thereof during distribution and storage. The...

Methods for the treatment of endometriosis
02/12/15 - 20150044291 - Endometriosis, including endometriosis externa, endometrioma, adenomyosis, adenomyomas, adenomyotic nodules of the uterosacral ligaments, and endometriotic nodules, such as scar endometriosis are effectively treated by the intralesional administration, including transvaginal, endoscopic or open surgical administration including via laparotomy, of a progestogen. Compositions therefor also are provided....

Cosmetic composition
02/05/15 - 20150037418 - and wherein, a mass ratio of the component (A) to the component (D), (A)/(D), is from 0.1 to 100....

Functional pla-peg copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging
02/05/15 - 20150037419 - Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging The present invention concerns novel functional PEG-PLA containing copolymers, the nanoparticles containing the same, their process of preparation and their use for site specific targeted drug delivery and imaging....

Methods and compositions for treating wounds and reducing the risk of incisional hernias
01/29/15 - 20150030678 - Provided are methods and compositions for treating a wound in a subject. The methods include applying a pharmaceutical composition that includes a first precursor material agent including fibrinogen, a second precursor material agent including thrombin, and silver particles to an abdominal incision site in an amount effective to treat the...

Dry powder formulations of dnase i
01/22/15 - 20150024050 - DNase I formulations for pulmonary administration and, more particularly, but not exclusively, a dry powder formulation comprising, as an active ingredient, human DNase I, methods, dry powder inhalation devices and systems for the therapeutic use thereof are provided....

Injectable hydrogel system to modulate host response at bone implant interface
01/22/15 - 20150024051 - A bone implant primer is provided. A biodegradable hydrogel component is provided. A plurality of biomolecule release depots are dispersed within the biodegradable hydrogel component wherein the plurality of biomolecule release depots comprise biomolecules for aiding implant osseointegration or biomolecules for mitigation of foreign body response. Different biomolecules may be...

Nitric oxide releasing pharmaceutical compositions
01/22/15 - 20150024052 - The present invention generally relates to nitric oxide releasing pharmaceutical compositions and methods of using the same....

Topical wound treatment method and composition
01/22/15 - 20150024053 - A topical wound treatment composition comprises a hydrogen peroxide generator; alkaline powder; not more than 5 percent by weight of water; additional topical active agent if desired, and emollient (preferably hygroscopic emollient) to balance. When topically applied to a wound and water from the surrounding environment diffuses into the composition,...

Solid pharmaceutical dispersions with enhanced bioavailability
01/22/15 - 20150024054 - Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or bioavailability in a use environment....

Enhanced immediate release formulations of topiramate
01/22/15 - 20150024055 - The present invention provides enhanced immediate release formulations of topiramate, in which 80% of the active ingredient is released in the period of time of not more than 30 min. These formulations may be advantageously used for the treatment of acute neurological conditions, such as migraine....

Controlled release sterile injectable aripiprazole formulation and method
01/22/15 - 20150024056 - A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle thereof, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A...

Dry powder formulation of azole derivative for inhalation
01/15/15 - 20150017244 - A spray dried-powder composition for inhalation comprising particles (X) containing (a) between 5 and 50% by weight of at least one azole derivative in amorphous state but not in crystalline structure and (b) at least one matricial agent to the composition selected from a group consisting of polyol such as...

Methods of treating cancers with therapeutic nanoparticles
01/15/15 - 20150017245 - The present disclosure relates in part to methods of treating cholangiocarcinoma or tonsillar cancer in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of a nanoparticle composition, wherein nanoparticle composition comprises nanoparticles....

Immune-modifying nanoparticles for the treatment of inflammatory diseases
01/08/15 - 20150010631 - The current invention involves the administration of negatively charged particles, such as polystyrene, PLGA, or diamond particles, to subjects to ameliorate inflammatory immune responses. Additionally, the present invention describes methods of treating inflammatory diseases by administering these same negatively charged particles....

Novel aerosol formulations of granisetron and uses thereof
01/08/15 - 20150010632 - Aerosol formulations of granisetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative...

Novel aerosol formulations of ondansetron and uses thereof
01/08/15 - 20150010633 - Aerosol formulations of ondansetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative...

Prevention and treatment of ocular conditions
01/08/15 - 20150010634 - The present invention relates to pharmaceutical compositions comprising hydrogel-linked prodrug for use in the treatment, prevention and/or diagnosis a condition of the eye and ophthalmic devices comprising said pharmaceutical compositions....

Controlled release particles, wood treatment agent, and producing method thereof
01/08/15 - 20150010635 - Controlled release particles are obtained by dissolving a hydrophobic antibiotic compound with a hydrophobic polymerizable vinyl monomer to prepare a hydrophobic solution, blending water with an emulsifier to prepare an aqueous emulsifier solution, emulsifying the hydrophobic solution in the aqueous emulsifier solution, and polymerizing the polymerizable vinyl monomer by mini-emulsion...

Apparatus and method for reducing the occurrence of post-surgical adhesions
01/08/15 - 20150010636 - A method for inhibiting formation of adhesions following abdominal surgery which involves application of an anti-static fatty acid ethoxylated amide (Cocamide DEA) in a matrix that is placed in the peritoneal cavity at the conclusion of an abdominal surgery and which releases this anti-adhesive chemical over a predetermined time in...

Aqueous suspensions of tmc278
01/08/15 - 20150010637 - This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the NNRTI compound TMC278, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of HIV infection....

Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
01/01/15 - 20150004232 - Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include uniform, rigid, spherical nanoporous calcium phosphate particles associated with one or more active agents. Also provided are methods of using the compositions in active agent delivery...

Respirably dry powder comprising calcium lactate, sodium chloride and leucine
01/01/15 - 20150004233 - The present invention relates to respirable dry powders that contain respirable dry particles that comprise about 20%-37.5% (w/w) leucine, about 58.6-about 75% (w/w) calcium lactate, and about 3.9-about 5% (w/w) sodium chloride, and methods for treating a subject using the respirable dry powders....

Nanoparticulate compositions and formulations of piperazine compounds
01/01/15 - 20150004234 - The present invention relates to storage stable nanoparticulate compositions of piperazine compounds. The pharmaceutical compositions comprising the nanoparticulate compositions that are useful for the treatment and prevention of proliferative diseases including cancer are also described....

Microporous zirconium silicate for the treatment of hyperkalemia
01/01/15 - 20150004235 - The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of...

Efficient process for the preparation of lycopene containing oleoresin and lycopene crystals for human consumption
01/01/15 - 20150004236 - The present invention provides a process for the preparation of lycopene containing oleoresin and lycopene crystals for human consumption. The present invention provides an efficient process for the preparation of lycopene crystals from lycopene containing oleoresin with at least 85% by weight lycopene, containing at least 90% by weight trans-lycopene...

Cellulose derivatives for inhibiting crystallization of poorly water-soluble drugs
01/01/15 - 20150004237 - is 3, 4, 6, or 8 to provide a ω-carboxyalkanoyl group chosen from succinoyl, glutaroyl, adipoyl, sebacyl, and suberyl groups; and wherein R is chosen from: a hydrogen atom; and an alkanoyl group chosen from acetyl, propionyl, butyryl, valeroyl, hexanoyl, nonanoyl, decanoyl, lauroyl, palmitoyl, and stearoyl groups; wherein there is...

Emulsions providing stable vitamin compositions and methods of forming compositions thereof
01/01/15 - 20150004238 - Stable vitamin oil-in-water emulsions and methods of making those emulsions are described herein. The emulsions may be used to make beverage products that include fat-soluble vitamins. The emulsions may also be used in beverage products that are colored and which maintain color stability for an extended period of time....