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Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form > Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets)

Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets)

Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets) patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

11/27/14 - 20140348921 - Novel hemostatic composition
the total quantity of water and humectant being comprised between 55 and 75% by weight relative to the total weight of the composition....

11/27/14 - 20140348922 - Process for producing a particulate composition comprising an hydrous crystalline 2-o-alpha-d-glucosyl-l-ascorbic acid
The invention provides a process for enabling the production of a particulate composition containing anhydrous crystalline ascorbic acid 2-glucoside that does not significantly cake even when the production yield of ascorbic acid 2-glucoside does not reach 35% by weight. The process for producing a particulate composition containing anhydrous crystalline ascorbic...

11/27/14 - 20140348923 - Polymeric drug-delivery material, method for manufacturing thereof and method for delivery of a drug-delivery composition
A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a polymer, and an aqueous solution. The dry powder, the pharmaceutically active compound and the aqueous solution are mixed to form a paste-like or semi-solid drug-delivery composition, wherein the...

11/27/14 - 20140348924 - Particles comprising single stranded rna and double stranded rna for immunomodulation
The present invention relates to chimeric particles comprising single stranded RNA (ssRNA), double stranded RNA (dsRNA) and at least one cationic agent, a pharmaceutical composition containing said particles and to a method of producing the same. The particles of the present invention are particularly useful as an immunostimulating medicament with...

11/27/14 - 20140348925 - Antioxidant ingredient with low calorie content, method for obtaining same and use thereof
The present invention relates to an antioxidant ingredient with low calorie content obtainable by a process that comprises the following steps: (a) selecting as raw material at least one fruit and/or plant material with high antioxidant content, greater than 6 g/100 g dry matter; (b) obtaining juice and pulp by...

11/27/14 - 20140348926 - Formulation and method for increasing oral bioavailability of drugs
The application discloses a formulation and method for increasing bioavailability of an orally administered drug....

11/27/14 - 20140348927 - Conditioning hair-cleaning agent
Cosmetic cleaning agents include in a cosmetically acceptable carrier a) at least one anionic surfactant, b) at least one cationic guar polymer, c) at least one silicone emulsion, in which the silicone particles have an average diameter of a maximum of 600 nm, and d) at least one wax. The...

11/27/14 - 20140348928 - Substituted n-aryl pyridinones
Disclosed herein are substituted N-Aryl pyridinone fibrotic inhibitors and/or collagen infiltration modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof....

11/27/14 - 20140348929 - Omega-3 fatty acid ester compositions
Described herein are compositions comprising at least one Omega-3 fatty acid ester and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided is a method of administering to a subject a composition comprising at least one Omega-3 fatty acid...

11/27/14 - 20140348930 - Omega-3 fatty acid ester compositions
Described herein are compositions comprising at least one Omega-3 fatty acid ester and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided is a method of administering to a subject a composition comprising at least one Omega-3 fatty acid...

11/20/14 - 20140341995 - Conjugate with target-finding ligand and use thereof
Described is a conjugate of agent complex and at least one target-finding ligand, where the agent complex comprises an agent encapsulated by an encapsulation material and where the target-finding ligand is a prostacyclin analog, and the use of the conjugate....

11/20/14 - 20140341996 - Nanoengineering of functionalized polymers and its manufacturing and formulation methods for personalized cancer therapies
Nanoengineering of inert polymers to develop functionalized sulfonated polymers to harness the power of Alternate complement system to stimulate and amplify cytotoxic potentials of classical and lectin based complement system Manufacturing functionalized sulfonated polymer to better penetrate tumor microenvironment, actively target various cancer antigens in conjunction with monoclonal antibodies in...

11/20/14 - 20140341997 - Continuous process for preparing microspheres and microspheres prepared thereby
When microspheres are prepared using the method of the present invention, scale variables, which have been the biggest disadvantage in existing preparation methods of microspheres, can be significantly reduced, drug encapsulation efficiency can be improved, and small and uniform particles can be obtained....

11/20/14 - 20140341998 - Pharmaceutical composition for inhalation
Said powder formulation makes inhalation therapy possible by carrying out aerosolization easily, and since pharmacological effect in lung local part is increased, it is possible to decrease the dose. Skin transmigration of said medicine is controlled by a lung specific delivery technology, and photodermatosis which is a side effect can...

11/20/14 - 20140341999 - Antitubercular composition and method for producing same
The invention relates to the field of pharmaceutics and medicine and concerns a medicinal composition of antitubercular preparations with a phospholipid transport system, the composition consisting of a fatty acid salt, phosphatidylcholine of vegetative origin (73-97%), maltose and an antitubercular agent selected from rifamycin, protionamide, rifabutin and rifapentine, and a...

11/20/14 - 20140342000 - Porous scaffold with carbon-based nanoparticles
A biocompatible porous scaffolds, especially bone regeneration scaffolds, comprising carbon-based nanoparticles, especially diamond nanoparticles, methods for the production of such biocompatible porous scaffolds, the use of such biocompatible porous scaffolds and methods for treating bone defects by inserting such biocompatible porous scaffolds comprising carbon-based nanoparticles into the bone defect....

11/20/14 - 20140342001 - Medicaments
There is described a bimodal pharmaceutical composition comprising effective amounts of a first active ingredient which substantially comprises a coarse fraction and a second active ingredient which substantially comprise a fine fraction characterized in that the coarse fraction possesses a greater mass median aerodynamic diameter than the fine fraction. There...

11/20/14 - 20140342002 - Particulate materials
Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing such particles or formulations. In one embodiment, a composition of an aerosol formulation is provided and contains a particulate active substance of non-micronized, solid particles having...

11/13/14 - 20140335184 - Nanoparticle assembly, preparation thereof, and active material delivering composite comprising the same
Provided are a nanoparticle assembly including a DNA hydrogel and gold nanoparticles, methods of preparing thereof, and an active material delivering composite including the same. The nanoparticle assembly has an excellent biocompatibility, an ability to prevent an accumulation of the nanoparticle assembly in a body, and is capable of being...

11/13/14 - 20140335185 - Novel microcarrier beads
The invention relates to a novel microcarrier bead; a method for producing same; a therapeutic comprising said microcarrier bead and attached thereto or grown thereon at least one selected cell or tissue type; a method for making said therapeutic; and a method of treatment involving the use of said microcarrier...

11/13/14 - 20140335186 - Methods and compositions for enhancing cd4+ regulatory t cells
Disclosed are methods and related compositions for administering immunosuppressants and therapeutic macromolecules for enhancing CD4+ regulatory T cells....

11/13/14 - 20140335187 - Compositions and methods for decreasing the effects of alcohol
The present invention relates probiotic compositions useful in accelerating alcohol catabolism in a subject....

11/13/14 - 20140335188 - Cosmetic preparation comprising pulverized hydrophobic substances
A substance, which is in principle insoluble in a cosmetic or dermatological preparation, is converted into a powdery product by absorption onto a carrier, wherein said powdery product can be distributed better in the preparation. The preparations comprise water and one or more hydrophobic substances or substance mixtures which are...

11/13/14 - 20140335189 - Intestinal peptide targeting ligands
Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by...

11/06/14 - 20140328917 - Organic compound nano-powder, method for producing the same and suspension
An organic compound nano-powder comprising a granular organic compound with an average particle diameter of 500 nm or less and a 90%-diameter of less than 1500 nm and a carbohydrate compound comprising at least any one of a sugar and a sugar alcohol and with amount of 0.3 times or...

11/06/14 - 20140328918 - Methods of treating a subject and related particles, polymers and compositions
Described herein are methods for treating a subject with combinations of polymer-agent particles and cyclodextrin polymer agent conjugates. The methods herein may be used to treat subjects identified with cancer, cardiovascular disorders, autoimmune disorders, or inflammatory disorders. Also described herein are compositions, dosage forms, and kits comprising polymer-agent particles and...

11/06/14 - 20140328919 - Polymer-agent conjugates, particles, compositions, and related methods of use
Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making...

11/06/14 - 20140328920 - System for the delivery of biologically active compounds into an organism and method for the preparation of said system
The invention relates to the field of pharmaceutics, pharmaceutical nano-technology and pharmacology and concerns a system for delivering biologically active agents into an organism, the system comprising a nano-diamond with a particle size of 2-10 nm, the surface of said particles being modified by chlorine with a chlorine content of...

11/06/14 - 20140328921 - Tolerogenic synthetic nanocarriers to reduce or prevent anaphylaxis in response to a non-allergenic antigen
This invention relates to methods for reducing or preventing anaphylaxis to non-allergenic antigens with compositions comprising immunosuppressants, and related compositions....

11/06/14 - 20140328922 - Local, concomitant administration of tolerogenic synthetic nanocarriers to reduce type i and type iv hypersensitivity
Disclosed are methods and related compositions for concomitantly, locally administering immunosuppressants and doses of therapeutic macromolecules for reducing Type I and Type IV hypersensitivity....

11/06/14 - 20140328923 - Dosing combinations for reducing undesired humoral immune responses
Disclosed are dosings of therapeutic macromolecules and immunosuppressants, in some embodiments attached to synthetic nanocarriers, in combination with dosings of therapeutic macromolecules without synthetic nanocarriers, and related methods that provide reduced humoral immune responses....

11/06/14 - 20140328924 - Delivery of immunosuppressants having a specified pharmacodynamic effective-life and antigen for the induction of immune tolerance
This invention relates to methods that provide immunosuppressants and therapeutic macromolecules that are administered within a pharmacodynamically effective window of the immunosuppressants to induce immune tolerance to the therapeutic macromolecules. The methods allow shifting the immune response in favor of tolerogenic immune response development specific to the therapeutic macromolecule....

11/06/14 - 20140328925 - Micronized tanaproget, compositions, and methods of preparing the same
The present invention provides compositions, desirably pharmaceutical compositions, containing micronized tanaproget. The compositions can also contain microcrystalline cellulose, croscarmellose sodium, anhydrous lactose, magnesium stearate, micronized edetate calcium disodium hydrous, and micronized sodium thiosulfate pentahydrate. The compositions are useful in contraception and hormone replacement therapy and in the treatment and/or prevention...

11/06/14 - 20140328926 - Modified hyaluronic acid polymer compositions and related methods
The present application provides compositions comprising hyaluronic acid having low levels of functional group modification, mixtures formed by controlled reaction of such lightly modified hyaluronic acid with suitable difunctional or multi-functional crosslinkers, and hydrogel precursor compositions and the resulting hydrogels. The compositions are lightly cross-linked and possess low pro-inflammatory properties...

11/06/14 - 20140328927 - Anti-cancer nanoparticle compositions and methods of use
The present invention encompasses a composition capable of delivering and expressing a nucleic acid encoding UDP-Glucuronosyltransferases, p53 or a combination thereof into a cell, and methods for treating tumors....

11/06/14 - 20140328928 - Stable aqueous suspension
An aqueous suspension of a hydrophobic nutrient is disclosed. In particular, the nutrient, in ester form, is combined with a selected dispersion aid and a dispersion agent(s), and then dispersed in an aqueous medium to form the suspension....

11/06/14 - 20140328929 - Method of preventing acute graft-versus-host disease using oral beclomethasone dipropionate
Results from two randomized trials have shown that oral beclomethasone dipropionate (BDP) is effective for treatment of acute gastrointestinal graft-versus-host disease (GVHD). Here, we report results of a double-blind, randomized placebo-controlled phase II study designed to test the hypothesis that acute GVHD could be prevented by administration of oral BDP,...

10/30/14 - 20140322328 - Dry powder formulations and methods of use
The subject technology relates generally to pulmonary delivery of NSAIDs, such as aspirin....

10/30/14 - 20140322329 - Multipurpose gel for vaginal dryness with direct and delayed effect
The present invention relates to topical vaginal compositions in gel form containing immune mediators, growth factors, chemotactic factors and antibacterial/antiviral factors extracted from bovine colostrum, and optionally other ingredients with complementary activity....

10/30/14 - 20140322330 - Methods for forming miniemulsions and use thereof for delivering bioactive agents
The present invention relates to methods of forming miniemulsions and use of the miniemulsions as a delivery system for bioactive agents. In particular, the present invention relates to methods for forming a miniemulsion comprising providing a first phase comprising a hydrophilic surfactant, lipophillic surfactant and water and a second phase...

10/30/14 - 20140322331 - Calcipotriol monohydrate nanocrystals
Calcipotriol monohydrate nanocrystals prepared by the process disclosed herein may be incorporated in a pharmaceutical composition for use in the prevention or treatment of dermal diseases and conditions....

10/30/14 - 20140322332 - Antagonists of muc1
The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics....

10/30/14 - 20140322333 - Chelated nanoceria for the treatment of oxidative stress
A process for making cerium-containing nanoparticles with biocompatible stabilizers is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid, a stabilizer (chelator) selected from the group consisting of nitrilotriacetic acid, ethylene glycol tetraacetic acid and diethylenetriaminepentaacetic acid, and an oxidant, is provided, followed by a heating step to...

10/30/14 - 20140322334 - Oral solid preparation comprising aripiprazole and method for producing oral solid preparation comprising aripiprazole
[Means for Achieving the Object] The present invention relates to an oral solid preparation comprising, as an active ingredient, a finely milled crystal obtained by milling an aripiprazole hydrate crystal, and a pharmaceutically acceptable carrier, the finely milled crystal having a mean particle size of 15 μm or less; and...

10/30/14 - 20140322335 - Suspensions of cyclosporin a form 2
Disclosed herein are methods of formulating cyclosporin A Form 2....

10/30/14 - 20140322336 - Sustained-release microspheres and methods of making and using same
Provided, among other things, are compositions and methods for making sustained-release microspheres, as well as a microsphere delivery system for the sustained release of an active agent. The microsphere delivery system comprises a homogenous mixture of biodegradable polymer, active agent, and a so-called release-modifying agent (including a pH-stabilizing agent), and...

10/30/14 - 20140322337 - Heat generating nanomaterials
The present invention relates to a heat-generating composition, comprising a hetero-structure nanomaterial which comprises (a) a first material comprising at least one component selected from the group consisting of a metal, a metal chalcogen, a metal pnicogen, an alloy and a multi-component hybrid structure thereof; and (b) a second material...

10/30/14 - 20140322338 - Flurbiprofen formulations
This invention relates to a pharmaceutical formulation, characterized by comprising flurbiprofen and polyvinylcaprolactam-polyvinyl acetate-polyethylene glycol graft copolymer....

10/23/14 - 20140314850 - Functionalized nanodiamonds as delivery platforms for nucleic acids
The present application relates to functionalized nanodiamonds, to complexes comprising a functionalized nanodiamond reversibly bound to a nucleic acid and to compositions comprising such functionalized nanodiamonds and complexes. In particular, the functionalized nanodiamonds comprise at least one naturally occurring basic amino acid, or analogs or derivatives thereof, covalently linked to...

10/23/14 - 20140314851 - Dairy product and process
The invention relates to liquid nutritional compositions, particularly shelf stable liquid nutritional compositions including compositions comprising non-hydrolysed whey protein, and methods of producing and using these compositions....

10/23/14 - 20140314852 - Nanoparticulate systems prepared from sorbitan esters
The invention relates to systems comprising homogenous nanoparticles having an average size of less than 1 micrometer and containing at least a sorbitan ester, a macrogol ester, a macrogol ether or a derivative of same and, optionally, at least one component derived from oxyethylene and/or at least one component having...

10/23/14 - 20140314853 - Microspheres for controlled- or sustained-release delivery of therapeutics
A new microsphere formulation (composition) for controlled- or sustained-release delivery of therapeutic ingredient(s), mainly peptides and proteins not over 10K in molecular weight, comprises at least a therapeutic ingredient, a helping agent (such as PH sensitive agent whose solubility is a function of pH) and a biodegradable polymer. The therapeutic...