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Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form > Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets)

Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets)

Particulate Form (e.g., Powders, Granules, Beads, Microcapsules, And Pellets) patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

10/30/14 - 20140322328 - Dry powder formulations and methods of use
The subject technology relates generally to pulmonary delivery of NSAIDs, such as aspirin....

10/30/14 - 20140322329 - Multipurpose gel for vaginal dryness with direct and delayed effect
The present invention relates to topical vaginal compositions in gel form containing immune mediators, growth factors, chemotactic factors and antibacterial/antiviral factors extracted from bovine colostrum, and optionally other ingredients with complementary activity....

10/30/14 - 20140322330 - Methods for forming miniemulsions and use thereof for delivering bioactive agents
The present invention relates to methods of forming miniemulsions and use of the miniemulsions as a delivery system for bioactive agents. In particular, the present invention relates to methods for forming a miniemulsion comprising providing a first phase comprising a hydrophilic surfactant, lipophillic surfactant and water and a second phase...

10/30/14 - 20140322331 - Calcipotriol monohydrate nanocrystals
Calcipotriol monohydrate nanocrystals prepared by the process disclosed herein may be incorporated in a pharmaceutical composition for use in the prevention or treatment of dermal diseases and conditions....

10/30/14 - 20140322332 - Antagonists of muc1
The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics....

10/30/14 - 20140322333 - Chelated nanoceria for the treatment of oxidative stress
A process for making cerium-containing nanoparticles with biocompatible stabilizers is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid, a stabilizer (chelator) selected from the group consisting of nitrilotriacetic acid, ethylene glycol tetraacetic acid and diethylenetriaminepentaacetic acid, and an oxidant, is provided, followed by a heating step to...

10/30/14 - 20140322334 - Oral solid preparation comprising aripiprazole and method for producing oral solid preparation comprising aripiprazole
[Means for Achieving the Object] The present invention relates to an oral solid preparation comprising, as an active ingredient, a finely milled crystal obtained by milling an aripiprazole hydrate crystal, and a pharmaceutically acceptable carrier, the finely milled crystal having a mean particle size of 15 μm or less; and...

10/30/14 - 20140322335 - Suspensions of cyclosporin a form 2
Disclosed herein are methods of formulating cyclosporin A Form 2....

10/30/14 - 20140322336 - Sustained-release microspheres and methods of making and using same
Provided, among other things, are compositions and methods for making sustained-release microspheres, as well as a microsphere delivery system for the sustained release of an active agent. The microsphere delivery system comprises a homogenous mixture of biodegradable polymer, active agent, and a so-called release-modifying agent (including a pH-stabilizing agent), and...

10/30/14 - 20140322337 - Heat generating nanomaterials
The present invention relates to a heat-generating composition, comprising a hetero-structure nanomaterial which comprises (a) a first material comprising at least one component selected from the group consisting of a metal, a metal chalcogen, a metal pnicogen, an alloy and a multi-component hybrid structure thereof; and (b) a second material...

10/30/14 - 20140322338 - Flurbiprofen formulations
This invention relates to a pharmaceutical formulation, characterized by comprising flurbiprofen and polyvinylcaprolactam-polyvinyl acetate-polyethylene glycol graft copolymer....

10/23/14 - 20140314850 - Functionalized nanodiamonds as delivery platforms for nucleic acids
The present application relates to functionalized nanodiamonds, to complexes comprising a functionalized nanodiamond reversibly bound to a nucleic acid and to compositions comprising such functionalized nanodiamonds and complexes. In particular, the functionalized nanodiamonds comprise at least one naturally occurring basic amino acid, or analogs or derivatives thereof, covalently linked to...

10/23/14 - 20140314851 - Dairy product and process
The invention relates to liquid nutritional compositions, particularly shelf stable liquid nutritional compositions including compositions comprising non-hydrolysed whey protein, and methods of producing and using these compositions....

10/23/14 - 20140314852 - Nanoparticulate systems prepared from sorbitan esters
The invention relates to systems comprising homogenous nanoparticles having an average size of less than 1 micrometer and containing at least a sorbitan ester, a macrogol ester, a macrogol ether or a derivative of same and, optionally, at least one component derived from oxyethylene and/or at least one component having...

10/23/14 - 20140314853 - Microspheres for controlled- or sustained-release delivery of therapeutics
A new microsphere formulation (composition) for controlled- or sustained-release delivery of therapeutic ingredient(s), mainly peptides and proteins not over 10K in molecular weight, comprises at least a therapeutic ingredient, a helping agent (such as PH sensitive agent whose solubility is a function of pH) and a biodegradable polymer. The therapeutic...

10/16/14 - 20140308351 - Method of forming non-immunogenic hydrophobic protein nanoparticles, and uses therefor
Methods are described for producing non-immunogenic nanoparticles from protein sources by controlling the pH in a nanoprecipitation process. The nanoparticles that are produced by the disclosed methods range in diameter size from about 100 ran to about 400 nm, with a preferred diameter size of from approximately 100 nm to...

10/16/14 - 20140308352 - Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent. Related compositions and methods are also disclosed....

10/16/14 - 20140308353 - Delivery of an active material
A composition for use as a topical delivery system for an active material is provided, the composition comprising a plurality of skin cell removal particles and a plurality of active material molecules, at least some of the skin cell removal particles each carrying at least one active material molecule, wherein...

10/16/14 - 20140308354 - Sustained release bimatoprost, bimatoprost analogs, prostamides and prostaglandins for fat reduction
The present invention is directed to compositions and methods for injection into fat deposits for sustained release of compounds which result in localized fat reduction....

10/16/14 - 20140308355 - Oral compositions containing polyorganosilsesquioxane particles
Oral compositions containing a polyorganosilsesquioxane particle, preferably polymethylsilsesquioxane particles and an orally-acceptable carrier containing a gel network. Method of using such compositions for the cleaning and polishing of dental enamel, such methods including the step of applying such oral care compositions to the teeth of a user....

10/16/14 - 20140308356 - Granular material for dosage forms
is useful for preparing dosage forms with a controlled release profile....

10/16/14 - 20140308357 - Melatonin-based solutions and powders for their preparation
The present invention relates to a powder for reconstitution before use for preparations for injection containing melatonin, at least one soluble excipient and at least one surfactant for the treatment of neonatal cerebral infarction. The present invention also relates to a preparation for injection in the form of a solution...

10/09/14 - 20140302145 - Pharmaceutical composition for treating cancer using carbonate apatite nanoparticles
A principal object of the present invention is to provide a pharmaceutical composition that can produce a high antitumor effect by efficiently delivering a drug with antitumor activity to tumor tissues with the aid of carbonate apatite nanoparticles. The present invention provides a pharmaceutical composition including carbonate apatite nanoparticles with...

10/09/14 - 20140302146 - Ophthalmic aqueous composition
The present invention provides an ophthalmic aqueous composition having an oil-in-water emulsion including a vegetable oil, a non-ionic surfactant, and a terpenoid, wherein an average particle diameter of emulsion particles is within the range of 30 nm to 300 nm....

10/09/14 - 20140302147 - Respirable agglomerates of porous carrier particles and micronized drug
Embodiments of the present invention provide a dry powder composition comprising porous carrier particles associated with one, two, three or more micronized drugs or APIs wherein an ordered mixture between the micronized drug or drugs and the carrier particle results, such that the micronized drug or drugs adhere strongly to...

10/09/14 - 20140302148 - Cannabinoid formulations
The present invention provides stable, fast-acting liposomal and micelle formulations of cannabinoids that are suitable for pharmaceutical and nutraceutical applications....

10/09/14 - 20140302149 - Selective chemokine modulation
A method of treating or preventing a disease characterized by adverse expression and/or release of 10 kDa interferon-γ inducible protein, IP-10, comprises administering granules or particles made of a metal or an oxide of a metal to a subject suffering from the disease. A method of reducing IP-10 in a...

10/09/14 - 20140302150 - Dpp-iv inhibitor formulations
The present invention relates to a pharmaceutical formulation, characterized by comprising a DPP-IV inhibitor and polyvinylcaprolactam-polyvinyl acetate-polyethylene glycol graft copolymer....

10/09/14 - 20140302151 - Methods and compositions for treating pain
Methods and compositions for treating pain are disclosed. The compositions are based on dry powders comprising microparticles of diketopiperazines and an analgesic active agent. The analgesic in the compositions comprises one or more peptide analgesics or derivatives thereof, which are administered to a subject using a pulmonary inhalation drug delivery...

10/02/14 - 20140294961 - Hepatic protection agent containing eggshell membrane and pharmaceutical composition, food additive and food using the same
The hepatoprotective agent contains eggshell membrane-containing fine powder, wherein the eggshell membrane-containing fine powder is eggshell membrane-containing fine powder having a volume mean particle diameter of 6 μm or less and/or eggshell membrane-containing fine powder having a volume maximum particle diameter of 20 μm or less. When fed with feed...

10/02/14 - 20140294962 - Method of preparing polymorphic pure form a of bazedoxifene acetate
The present invention provides a reliable process for the preparation of polymorphic pure form A of Bazedoxifene x acetate. In addition, the present invention relates to a process of wet granulation of polymorphic pure form A of Bazedoxifene x acetate. The present invention also relates to pharmaceutical compositions comprising polymorphic...

10/02/14 - 20140294963 - Novel gold-platinum based bi-metallic nanocrystal suspensions, electrochemical manufacturing processes therefor and uses for the same
The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are “clean” relative to the surfaces of metal-based...

10/02/14 - 20140294964 - Compositions and methods for treating cancer with dacarbazine nanoemulsions
A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of anticancer agents. As a nanoemulsion, dacarbazine has a greater anti-cancer efficacy than when...

10/02/14 - 20140294965 - Compositions and methods for exfoliating particles
Various embodiments provide compositions for exfoliating particles and methods for their manufacture. In one exemplary embodiment, the exfoliating particles may comprise a derivative of a botanically-sourced emollient, stearyl stearate, and at least one of: candelilla wax, is bran wax, sunflower wax, jojoba esters, carnauba wax, bees wax, corn wax, a...

10/02/14 - 20140294966 - Stable nanocomposition comprising docetaxel, process for the preparation thereof, its use and pharmaceutical compositions containing it
A nanoparticulate composition is disclosed for the targeted therapeutic treatment of tumours. The stable self assembled nanocomposition according to the invention comprises (i) a carrier and targeting system comprising an optionally modified polyanion, and optionally a polycation, which may also be modified; at least one targeting agent which is linked...

10/02/14 - 20140294967 - Stable nanocomposition comprising paclitaxel, process for the preparation thereof, its use and pharmaceutical compositions containing it
A nanoparticulate composition is disclosed for the targeted therapeutic treatment of tumours. The stable self assembled nanocomposition according to the invention comprises (i) a carrier and targeting system comprising an optionally modified polyanion, and optionally a polycation, which may also be modified; at least one targeting agent which is linked...

10/02/14 - 20140294968 - Polyacrylate-based active compound-comprising particles
The invention relates to novel polyacrylate-based active compound-comprising particles which bind to hair, and to the use of these particles for preparing medicaments, in particular for veterinary medicine. The particles comprise uncharged and cationic polyacrylate and are at most 10 um big....

10/02/14 - 20140294969 - Method and formulation for inhalation
This invention relates to drug delivery and in particular to the delivery of biologically active agents in the form of dry powders for inhalation. The invention also relates to methods for preparing such dry powder formulations and methods for their use....

10/02/14 - 20140294970 - Stabilized pharmaceutical sub-micron suspensions and methods of forming same
The present invention is directed to a pharmaceutical submicron suspension and a method of forming the submicron suspension. The submicron suspension is useful for delivery of relatively hydrophobic and/or low solubility therapeutic agent. The submicron suspension and method of forming the submicron suspension typically employ a polymeric material that aids...

10/02/14 - 20140294971 - Cancer cell-inhibiting ceramic, process for producing cancer cell-inhibiting ceramic, method for treating bone tumor, and use of beta-tricalcium phosphate porous granules with particle size of 1 to 10 micrometer
Proliferation of cancer cells is effectively inhibited. Provided is a cancer cell-inhibiting ceramic containing a β-tricalcium phosphate porous granule with a particle size of 1 to 10 μm. The β-tricalcium phosphate porous granule is taken up into cancer cells at an affected area and have an effect of inhibiting proliferation...

10/02/14 - 20140294972 - Oral suspension
A liquid pharmaceutical composition for use in the treatment of acute lymphoblastic leukaemia (ALL) comprising 6-mercaptopurine or a salt, hydrate or solvate thereof and a pharmaceutically-acceptable excipient, wherein the composition is a suspension for oral administration, a kit of parts for the accurate dosing and administration of the liquid pharmaceutical...

10/02/14 - 20140294973 - Pharmaceutical compositions of hydrophobic camptothecin derivatives
The present invention provides a pharmaceutical composition comprising at least one hydrophobic camptothecin derivative or a pharmaceutically acceptable salt of said derivative and a polyethylene glycol (PEG) conjugated phospholipid. Also provided is a method to inhibit cancer cells in a subject in need thereof by administering the pharmaceutical composition of...

10/02/14 - 20140294974 - Cosmetic composition
The invention relates to a cosmetic composition comprising an emulsion comprising hydrophobically modified particles, amino functionalized silicone and water; the cosmetic composition further comprising a moisturizing agent and at least one component selected from the group consisting of vitamin, anti-dandruff agent and surfactant, wherein the composition comprises at least a...

10/02/14 - 20140294975 - Solid anti-sun composition based on lipophilic organic uv screening agent and aerogel particles of hydrophobic silica
The present invention thus relates to a solid composition, in particular in the form of a loose or compact powder, comprising, in a cosmetically acceptable medium: a) at least one pulverulent phase; b) at least one lipophilic organic UV screening agent characterized in that the pulverulent phase comprises at least...

10/02/14 - 20140294976 - Cosmetic preparation comprising pulverized hydrophilic substances
A substance, which is in principle insoluble in a cosmetic or dermatological anhydrous preparation is converted into a powdery product by absorption onto a carrier, the powdery product being soluble in the preparation. The anhydrous preparations comprise one or more hydrophilic substances or substance mixtures which are liquid, pasty at...

10/02/14 - 20140294977 - Radiation-sterilized biodegradable drug delivery composition
The present disclosure is directed to a method of making a composition by combining a vehicle, e.g., a single phase vehicle, and an insoluble component comprising a beneficial agent, and sterilizing the composition using ionizing radiation prior to use, wherein the beneficial agent is stable following exposure to a sterilizing...

09/25/14 - 20140287043 - Compositions and methods for stabilization of active agents
Provided herein are methods and compositions for stabilization of active agents. The active agents are distributed, mixed or embedded in a silk fibroin matrix, thereby retaining the bioactivity of the active agents upon storage and/or transportation. In some embodiments, the storage-stable vaccine-silk compositions are also provided herein....

09/25/14 - 20140287044 - Fibrin sealant (fibringluraas) consisting of a kit of lyophilized or frozen high concentrate fribinogen
The application is directed to a fibrin sealant (FIBRINGLURAAS®) consisting of a kit of lyophilized or frozen high concentrate fribinogen in which 5% a1at will be added into the final bulk and or 5% a1at as a diluent for high concentrate fibrinogen and new found proteins kh30, kh31, kh32, kh44,...

09/25/14 - 20140287045 - Method of preparing microspheres by using polymer having sol-gel transition property and microspheres prepared thereby
The present invention relates to a method of preparing microspheres by using a polymer having a sol-gel transition property and microspheres prepared thereby, and more particularly, to a method of preparing microspheres by using a polymer having a sol-gel transition property and microspheres prepared thereby capable of preventing a solvent...

09/25/14 - 20140287046 - Non-fluoride containing dietary supplement toothpaste and methods of using the same
A non-fluoride containing toothpaste enriched with at least one dietary supplement. The non-fluoride containing toothpaste comprising a dentally acceptable oral vehicle containing a sufficient amount of thickening agent to impart a pasty consistency; and at least one dietary supplement wherein a serving size portion of the non-fluoride containing toothpaste contains...

09/25/14 - 20140287047 - Nanoemulsion therapeutic compositions and methods of using the same
The present invention relates to methods and compositions for treating pulmonary infection. In particular, the present invention provides nanoemulsion compositions and methods of using the same to treat bacteria associated with biofilms (e.g., found in pulmonary infections). Compositions and methods of the present invention find use in, among other things,...

09/25/14 - 20140287048 - Paste comprising non-steroidal anti-inflammatory drug
An oral paste comprising: (i) at least one non-steroidal anti-inflammatory drug; (ii) at least one viscosity modifying agent; and (iii) a liquid vehicle....

09/25/14 - 20140287049 - Nanoparticle-based drug delivery
Embodiments provide systems, methods, and compositions for nanoparticle-based drug delivery to target cells or tissues. A drug delivery system may include a nanoparticle with a targeting component and a therapeutic component. The nanoparticle may have a predetermined number or valence of targeting molecules for multivalent interaction with a target cell...