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Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form > Matrices

Matrices

Matrices patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

08/02/07 - 20070178160 - Gastro-intestinal device and method for treating addiction
A device and a method for treating a medical condition include a reversible member disposed in a patient's gastro-intestinal tract, and a dispensing member coupled to the reversible member that delivers a drug and/or a noxious when a predetermined substance is detected. In a different embodiment, the device and method ...

08/02/07 - 20070178159 - In-situ forming porous scaffold
A composition includes a viscous gel formed from a combination of a biodegradable polymer and a biocompatible solvent. The composition also includes a hydrophilic porogen, which may be incorporated in the viscous gel. The composition may form a porous scaffold in situ. ...

08/02/07 - 20070178158 - Stabilized bone graft
A demineralized bone matrix (DBM) or other matrix composition is provided that has been stabilized by lowering the pH of the composition, reducing the water content, adding water substitutes, and/or increasing the amount of deuterated water present in the composition in order to reduce the activity of endogenous degrading enzymes ...

07/26/07 - 20070172526 - Radiopaque fibers and filtration matrices
Medical devices with radiopaque three dimensional filtration matrices provide for improved visualization of the device within a vessel. In some embodiments, the three dimensional filtration matrix comprises fibers, such as surface capillary fibers. Visualization of the three dimensional filtration matrix provides for an evaluation of the proper deployment of the ...

07/12/07 - 20070160671 - Biguanide formulations
In certain embodiments, the invention is directed to a pharmaceutical dosage form consisting essentially of a single phase matrix comprising metformin or a pharmaceutically acceptable salt thereof and at least one controlled release excipient; said dosage form providing a mean Tmax of metformin from about 3 to about 12 hours ...

07/05/07 - 20070154552 - Biologically active native biomatrix composition
The present disclosure relates to a biologically active biomatrix composition. In one embodiment, the biomatrix composition is derived from human amnions. The biomatrix is termed HuBiogel™. The composition of HuBiogel™ closely mimics naturally occurring basement membrane compositions and is capable of supporting a wide variety of cell types in vitro ...

06/28/07 - 20070148243 - Containment of a treatment agent in a body vessel
Medical devices useful for the containment of a treatment agent in a body vessel are described. The medical devices comprise a compressible plug having compressed and uncompressed diameters. Upon delivery to a treatment site in a body vessel, the compressible plug expands to engage the interior wall of the body ...

06/28/07 - 20070148242 - Preparation for repairing cartilage tissue, especially articular cartilage defects
The invention relates to preparations which are suitable for repairing enchondral or osteochondral defects (4) by means of implantation, said preparations comprising a cartilage element (A) and optionally a bone element (B) which is connected to the cartilage element (A). The cartilage element (A) can already contain cells during the ...

05/10/07 - 20070104790 - Mesoporous compositions for use in drug delivery
The present invention encompasses novel mesoporous compositions comprising vitamin E and alumina, and methods for their synthesis. The mesoporous compositions of the present invention have applications as drug-delivery vehicles. ...

04/19/07 - 20070087059 - Bioactive delivery matrix compositions and methods
Bioactive delivery matrix compositions and methods of making and using such compositions. ...

03/29/07 - 20070071823 - Polyampholytes for delivering polyions to a cell
An polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to ...

03/01/07 - 20070048381 - Methods for promoting growth of bone, ligament, and cartilage
Methods for promoting growth of bone, ligament, or cartilage in a mammal are disclosed. The methods comprise administering to said mammal a composition comprising a pharmacologically effective amount of a zvegf3 protein in combination with a pharmaceutically acceptable delivery vehicle. Also disclosed are methods for promoting proliferation or differentiation of ...

12/14/06 - 20060280796 - Inositol-based molecular transporters and processes for the preparation thereof
Inositol derivatives in accordance with the present invention are effective in significantly enhancing the transportation of various therapeutic molecules across a biological membrane, which may include the plasma membrane, nuclear membrane or blood-brain barrier. ...

11/23/06 - 20060263430 - Instrument for inducing cytokine and method of inducing cytokine
There are provided a cytokine-inducing instrument and a cytokine-inducing method, which can more effectively induce cytokine as compared with the previous cytokine-inducing method. A cytokine-inducing instrument comprising a cytokine-inducing agent, and a carrier of a water-insoluble porous material, and cytokine-inducing method for inducing cytokine from a cell producing cytokine, using ...

10/26/06 - 20060240109 - Cellulosic and lignocellulosic materials and compositions and composites made therefrom
Cellulosic or lignocellulosic materials, and compositions and composites made therefrom, are disclosed. ...

10/05/06 - 20060222711 - Composition of and method for preparing stable particles in a frozen aqueous matrix
The present invention discloses a composition of a stable suspension of a poorly water soluble pharmaceutical agent or cosmetic in the form of particles of the pharmaceutical agent or cosmetic suspended in a frozen aqueous matrix and method for its preparation. The composition is stable for a prolonged period of ...

10/05/06 - 20060222710 - Composition of and method for preparing stable particles in a frozen aqueous matrix
The present invention discloses a composition of a stable suspension of a poorly water soluble pharmaceutical agent or cosmetic in the form of particles of the pharmaceutical agent or cosmetic suspended in a frozen aqueous matrix and method for its preparation. The composition is stable for a prolonged period of ...

09/28/06 - 20060216351 - Pharmaceutical compositions of dispersions of drugs and neutral polymers
In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed. ...

09/28/06 - 20060216350 - Ganglionic blocking agents for the treatment of epithelial diseases
Compositions, and methods of making and using a composition, containing a ganglionic blocking agent and water provide increased penetration of the ganglionic blocking agent into and through epithelial surfaces, such as skin and mucosal surfaces, provide increased release from formulations containing such ganglionic blocking agents, and provide increased antiviral effectiveness ...

09/21/06 - 20060210634 - Ceramic structures for controlled release of biologically active substances
The present invention provides compositions for controlled drug delivery, dosage forms, and processes for producing dosage forms. In a composition aspect of the present invention, a composition including a drug and a ceramic structure is provided. The ceramic structure has either a hollow portion wherein the drug is included in ...

07/06/06 - 20060147532 - Microparticles prepared using an ionic liquid
Microparticles comprising at least one active agent embedded within a biocompatible, biodegradable polymeric matrix, wherein said microparticles are prepared with an ionic liquid. ...

06/15/06 - 20060127480 - Pharmaceutical excipients comprising inorganic particles in association with an organic polymeric material and forming a solid reticulated matrix, compositions, manufacturing and use thereof
A pharmaceutical excipient comprising a solid, reticulated matrix, wherein the matrix comprises an aggregation of inorganic particles in association with an organic polymeric material, defines a plurality of pores with a mean width in the range of about 0.01-500 m, and has a specific surface area of at least about ...

06/01/06 - 20060115531 - Protein-based polymer tissue adhesives for medical use
Tissue adhesives formed by crosslinking albumin and/or gelatin with certain polyamines and/or polycarboxylates using a water-soluble carbodiimide are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; drug ...

05/25/06 - 20060110457 - Heat cured gel and method of making
A method of curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or ...

05/18/06 - 20060105043 - Porous nanostructures and methods involving the same
A method for simultaneously detecting and separating a target analyte such as a protein or other macromolecule that includes providing a porous silicon matrix on the silicon substrate, exposing the porous silicon matrix to an environment suspect of containing the target analyte, observing optical reflectivity of the porous silicon matrix; ...

05/18/06 - 20060105042 - Methods for making and delivering rho-antagonist tissue adhesive formulations to the injured mammalian central and peripheral nervous systems and uses thereof
The present invention provides methods for making, delivering and using formulations that combine a therapeutically active agent(s) (such as for example a Rho antagonist(s)) and a flowable carrier component capable of forming a therapeutically acceptable matrix in vivo (such as for example tissue adhesives), to injured nerves to promote repair ...

03/30/06 - 20060068013 - Non-adhesive elastic gelatin matrices
The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making ...

03/23/06 - 20060062852 - Medical device for analyte monitoring and drug delivery
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and ...

03/16/06 - 20060057207 - Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
A fast disintegrating dosage form of varenicline comprising an effective amount of varenicline or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable excipient, wherein the dosage form disintegrates in a patient's oral cavity in less than three minutes. Also provided are a method for reducing nicotine addiction, ...

03/02/06 - 20060045914 - Matrix composition for stable microemulsions
A matrix composition for making a stable microemulsion for an active ingredient includes a C8-C18 N-alkyl pyrrolidone with little or no N-methyl pyrrolidone, and a water-insoluble organic solvent soluble therein, preferably more hydrophilic than said C8-C18 alkyl pyrrolidone and with low water solubility. ...

02/23/06 - 20060039978 - Self-forming phospholipidic gels
A phospholipid gel is spontaneously formed when combining a first phospholipid, a second phospholipid, and water, wherein the first phospholipid is a neutral phospholipid and the second phospholipid is a negatively charged phospholipid. The first and second phospholipids are of natural origin, semi-synthetic origin, or synthetic origin. Preferably, they are ...

02/16/06 - 20060034930 - Apparatus and methods for sealing a vascular puncture
Apparatus for sealing a puncture communicating with a blood vessel includes a porous carrier formed from lyophilized hydrogel or other material. The plug may include at least first and second hydrogel precursors and a pH adjusting agent carried by the porous carrier in an unreactive state prior to exposure to ...

02/09/06 - 20060029672 - Silicone gel composition and dispenser therefor
A therapeutic silicone composition and a delivery device operable for the self-administration of the therapeutic silicone composition to the skin. Silicone gel compositions are known in the art to promote wound healing and reduce scarring. The therapeutic silicone composition of the present invention contains a silicone gel formulated with inert ...

02/02/06 - 20060024370 - Modafinil oral lyophilizate
The invention concerns an oral lyophilizate comprising modafinil particles having a median diameter of about 10 to about 1000 μm in association with an appropriate amount of at least one excipient selected from the group consisting of fatty acid esters of glycerol, cyclic oligosaccharides, sweeteners or mixtures thereof. ...

02/02/06 - 20060024369 - Chlorine dioxide releasing composite article
A composite article that includes a ClO2-producing material integrated into an organic matrix and methods of using the same are described. The organic matrix of the composite article is formable at a temperature under about 150° C., permits contact between an activating stimulus (e.g., water vapor and/or electromagnetic energy) and ...

01/26/06 - 20060018966 - Antimicrobial mesoporous silica nanoparticles
Methods for preparing a series of mesoporous silicates, such as room-temperature ionic liquid (RTIL)-templated mesoporous silicate particles, with various particle morphologies are provided. Methods for preparing silicate particles with antimicrobial agents within the MSN pores is also provided. The particles can be used as controlled-release nanodevices to deliver antimicrobial agents. ...

01/19/06 - 20060013878 - Process for forming a gel containing an ingredient therein
A process for absorbing an ingredient into a gel item to form a gel has the steps of providing an ingredient and a liquid media, homogenizing the ingredient and the liquid media in a mixer to form a mixture, providing a gel item capable of absorbing the liquid media and ...

01/19/06 - 20060013877 - Hybrid of itraconazole, cyclosporine or carvedilol with a layered silicate and a process for preparing the same
The present invention provides the hybrids wherein itraconazole, cyclosporine or carvedilol are intercalated into the interlayers and/or absorbed onto the surfaces of layered silicates. The hybrids according to the present invention enable the maximization of bioavailability of drugs by dissolving the drugs from the layered silicates. Furthermore, the present invention ...

01/12/06 - 20060008528 - Fullerences to increase radiation resistance in polymer-based pellicles
A pellicle made of a polymer material contains fullerenes within the polymer material to reduce the damaging effects of radiation that is transmitted through the pellicle during an exposure operation. The fullerenes may comprise nanotubes and/or buckyballs. The buckyballs may also enclose molecules of a gas that further reduce the ...

12/01/05 - 20050266083 - Vehicles for delivery of biologically active substances
A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administration of the pharmaceutical formulation. ...

12/01/05 - 20050266082 - Preparation of stable paroxetine hc1 er tablets using a melt granulation process
A pharmaceutical composition comprising a hydrophobic matrix comprised of paroxetine HCl and a lipid component is provided. The matrix also preferably contains hydrophilic polymers, e.g., hypromellose. This invention also relates to a method of making such a composition by melt granulating paroxetine HCl with a molten binder comprising a lipid ...

12/01/05 - 20050266081 - Antimicrobial silver hydrogels
An antimicrobial hydrogel composition contains at least one antimicrobial silver salt; at least one viscosity-enhancing agent chosen from natural clay and synthetic clay; and at least one electrolyte. Methods of making the composition, methods of disinfecting, and methods of treating are also disclosed. ...

11/17/05 - 20050255159 - Porous calcium phosphate networks for synthetic bone material
A porous composition comprising a hydroxyapatite material, as can be made from a mixture of calcium phosphate, calcium oxide and a removable inorganic porogen. In other embodiments, the present invention provides a method of making such a porous hydroxyapatite material or using a ternary system to prepare a two-phase composition ...

11/03/05 - 20050244499 - Method and device for reducing susceptibility to fractures in long bones
The invention provides a method and a device for administering bone matrix with or without additional bone growth enhancing agents, or administering one or more bone growth enhancing agents to the interior surface of a long bone and to the cancellous bone within the medullary cavity to enhance bone growth ...

10/20/05 - 20050232997 - Pharmaceutical formulations
Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of ...

10/20/05 - 20050232996 - Matrix comprising a bioactive component containing phospholipid
The present invention concerns a matrix with a bioactive component containing phospholipid which is composed of 5 to 98% by weight phosphatidyl serine and 1 to 90% by weight phosphatidyl choline. In addition 1 to 94% by weight of a fat component of vegetable and/or animal origin, a wax component, ...

09/29/05 - 20050214374 - Artificial extracellular matrix and process for producing the same
The artificial extracellular matrix of the present invention comprises heat stable fish collagen produced from fish collagen with a heat denaturation temperature lower than 37° C. by improving its heat stability. The artificial extracellular matrix of the invention has an adequate stability in living bodies and a function to activate ...

07/07/05 - 20050147679 - Composition and method for healing tissues
The composition and method for healing tissues is a medicinal composition for facilitating the growth, protection and healing of tissues and cells in animals and humans. The composition is formulated as a either a powder, gel, paste, film, fluid injectable, rehydratable freeze-dried paste or sponge, sprayable solution, topically applied patch ...

06/30/05 - 20050142200 - Antimicrobial concentrates
An antimicrobial concentrate is manufactured from a carrier, one or more antimicrobial agents and optionally one or more modifiers, the carrier having a modified ethylene polymer and optionally an olefin polymer and a method of producing the concentrate by producing the carrier, having the modified ethylene polymer and optionally the ...

06/02/05 - 20050118269 - External preparation for wounds
There is provided an external preparation for wounds which has novel usability in treating skin damages accompanied by a large amount of exudation such as bedsores, skin ulcers, and burns, and yet has such advantages as observed in conventional medicines having been employed in treating these wounds. The external preparation ...



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