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Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form > Tablets, Lozenges, Or Pills Tablets, Lozenges, Or PillsTablets, Lozenges, Or Pills patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.08/02/07 - 20070178154 - Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet ... 08/02/07 - 20070178153 - Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet ... 08/02/07 - 20070178152 - Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents Disclosed herein are pharmaceutical compositions comprising carboxyalkylcellulose esters for delivery of pharmaceutically active substances having low solubility in a medium such as water, an acidic aqueous buffer, a neutral aqueous buffer, or a basic aqueous buffer. Also disclosed are methods for making pharmaceutical compositions and methods of administering the compositions. ... 08/02/07 - 20070178151 - Spray dried pharmaceutical compositions The present invention relates to novel compositions containing the NK3 receptor antagonist talnetant which compositions have enhanced bioavailability. In addition, the invention relates to processes for the preparation and to uses of the compositions in therapy. ... 08/02/07 - 20070178150 - Pharmaceutical compositions A pharmaceutical composition in the form of a chewable tablet for the suppression of gastric reflux comprising an alginic acid or salt thereof, a water-soluble carbonate radical precursor, a calcium salt, a first bulk sweetener, and a binding agent. The calcium salt and either or both of the bulk sweetener ... 07/26/07 - 20070172524 - Process for preparing a solid pharmaceutical composition The invention relates to a process for preparing a solid pharmaceutical composition of perindopril or a salt thereof which avoids a wet granulation step and results in very stable pharmaceutical compositions, like tablets. ... 07/19/07 - 20070166376 - Solid pharmaceutical preparation The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which shows in vivo dissolution behavior of an insulin sensitizer, which is similar to the dissolution behavior of an insulin sensitizer from “a solid preparation containing an insulin sensitizer alone as an ... 07/12/07 - 20070160666 - Pharmaceutical formulation The instant invention provides a pharmaceutical composition comprised of a cholesterol absorption inhibitor and an HMG-CoA reductase inhibitor, one or more anti-oxidants, microcrystalline cellulose, hydroxypropyl methylcellulose, magnesium stearate and lactose. The composition need not contain ascorbic acid in order to obtain desirable stability. ... 07/12/07 - 20070160665 - Chlorthalidone combinations The invention relates to favourable combinations of the thiazide diuretic chlorthalidone with Angiotensin II Receptor Blockers (ARBs) for the treatment of hypertension. ... 07/05/07 - 20070154545 - Dry formulations of aripiprazole The invention encompasses dry compression pharmaceutical compositions of aripiprazole, methods of making tablets from the compositions, and tablets of the dry compression pharmaceutical composition. ... 07/05/07 - 20070154544 - Wet formulations of aripiprazole The invention encompasses wet granulation pharmaceutical compositions of aripiprazole, methods of making tablets from the compositions, and tablets of the wet granulation pharmaceutical composition. ... 07/05/07 - 20070154543 - Solid preparation for oral use Upon performing the clinical study of (S)-2-[3-[N-[4-(4-fluorophenoxy)benzyl]carbamoyl]-4-methoxybenz yl]butanoic acid (hereinafter abbreviated as KRP-101), of which improvement in the lipidmetabolism is expected in a microdose, no oral solid dosage form that allows KRP-101 to be administered quantitatively has been embodied. After mixing KRP-101 with additives (excipient, disintegrator and lubricant), the mixture ... 06/28/07 - 20070148236 - Pharmaceutical compositions of adsorbates of amorphous drug Pharmaceutical compositions comprise a low-solubility drug adsorbed onto a high surface area substrate to form an adsorbate. The compositions in some embodiments include a concentration-enhancing polymer. ... 06/28/07 - 20070148235 - Pharmaceutical composition The present invention relates to a granular pharmaceutical composition comprising a drug having a disagreeable taste, a wax and a sugar alcohol; a method for preparing the same; and a pharmaceutical product for oral administration, comprising the granular composition. The product excellently masks a disagreeable taste possessed by a drug ... 06/28/07 - 20070148234 - Pharmaceutical formulations The present invention relates to oral formulations comprising an active agent comprising at least one of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, salts of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid or buffered 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid. ... 06/28/07 - 20070148233 - Pharmaceutical formulations of fenofibrate having improved bioavailability Provided are pharmaceutical compositions of fenofibrate, and dosage forms containing them, that include fenofibrate, a polyethylene glycol, and a polyethylene-polypropylene glycol; wherein the compositions are made by subliming a sublimable carrier from a combination of fenofibrate, the polyethylene glycol, and the polyethylene-polypropylene glycol with the sublimable carrier, for example menthol. ... 06/28/07 - 20070148232 - Stabilized pharmaceutical solid compositions of low-solubility drugs and poloxamers, and stabilizing polymers Solid compositions with improved physical stability comprise an amorphous, low-solubility drug, a poloxamer, and a stabilizing polymer. The compositions provide good physical stability during storage and concentration enhancement of dissolved drug when administered to an aqueous environment of use. ... 06/28/07 - 20070148231 - Fast-disintegrating tablets The invention relates to a method of manufacture of fast-disintegrating tablets, and tablets obtained comprising chemicals, foodstuff, oral drug components and the like. The method is characterized in that the components in pulverized form are contacted with a pressurized liquefied gas or gas mixture, homogenized, introduced into moulds under pressure, ... 06/28/07 - 20070148230 - Medicament-containing particle and a solid preparation containing the particle The invention provides a medicament-containing particle wherein an unpleasant taste of the medicament is alleviated, which is obtainable by mixing and granulating the following ingredients: (1) the medicament with an unpleasant taste, (2) methylcellulose and (3) mannitol; and a solid preparation including the particle. The invention can make an unpleasant ... 06/28/07 - 20070148229 - Tablet with coloured core Press-coated tablets comprising a care and a coating. The core contains an active substance and a colouring agent such that when the tablet is exposed to penetrating radiation the core is contrasted with the coating and is visible through the coating. The invention also relates to the use' of a ... 06/21/07 - 20070141145 - Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same The present invention relates, in part, to a biocompatible hydrophobic-core carrier comprising a carrier, and a plurality of hydrophobic groups covalently linked to the polymeric carrier. The hydrophobic groups are capable of dissociably linking load molecules such as therapeutic agents. The hydrophobic-core carrier may also comprise protective side chains, orienting ... 06/21/07 - 20070141144 - Oral delivery system The present invention relates generally to formulations comprising paracetamol. More particularly, the present invention provides a swallow formulation comprising paracetamol which facilitates the rapid delivery of paracetamol into the circulatory system following oral administration. The present invention further relates to methods for inducing efficient pain relief including an analgesic effect ... 06/21/07 - 20070141143 - Solid compositions of low-solubility drugs and poloxamers Solid compositions of low-solubility drugs and poloxamers that provide concentration enhancement when administered to an aqueous environment of use are disclosed. ... 06/21/07 - 20070141142 - Pseudo-thermosetting neutralized chitosan composition forming a hydrogel and a process for producing the same The composition disclosed is a pseudo-thermosetting neutralized chitosan composition, neutralized with an hydroxylated base, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C. Said composition contains a homogeneously reacetylated chitosan derived from a chitosan having a deacetylation degree of 80-90%, having a molecular weight of not smaller ... 06/21/07 - 20070141141 - Pharmaceutical composition An immediate release pharmaceutical composition comprising 4-(3′-chloro-4′-fluoroanilino)-7-methoxy-6-(3-mor-pholinopropoxy)quinazoline or a pharmaceutically-acceptable salt thereof (the Agent); a water-soluble acid; and a water-soluble cellulose ether or an ester of a water-soluble cellulose ether. The claimed compositions inhibit the rate of precipitation of the Agent from solution and/or provide enhanced solubilisation of the agent ... 06/21/07 - 20070141140 - Semi-solid formulations for immediate release intended for the oral administration of drugs The present invention relates to a pharmaceutical composition suitable for oral administration, in the form of semisolid matrix, comprising an active ingredient poorly soluble in water and present in a quantity of from 15 to 45% by weight of the percent composition of the pharmaceutical composition; a surfactant agent constituted ... 06/14/07 - 20070134325 - Beta-lactam antibiotic-containing tablet and production thereof This invention provides β-lactam antibiotic-containing tablets capable of being orally taken either as such owing to their being small-sized, hence still easily swallowable, or, in the case of administration to the aged encountering some difficulty in swallowing, in the form of dispersions resulting from easy self-disintegration upon being dropped into ... 06/14/07 - 20070134324 - Therapeutic combinations The goal of the present invention is a pharmaceutical composition including a betaine and an anti-cholesterol agent. The association and co-administration of at least a betaine allows to reducing side effects related to anti-cholesterol agents administration, in particular their deleterious effects on liver, pancreas and kidneys. ... 06/14/07 - 20070134323 - Ziprasidone suspension Compositions comprising ziprasidone free base or a difficult to wet pharmaceutically acceptable ziprasidone acid addition salt, a polysorbate, and colloidal silicon dioxide form good aqueous suspensions having a useful shelf life and are easily re-suspended if settling occurs. ... 06/14/07 - 20070134322 - Modified and pulsatile release pharmaceutical formulations of escitalopram The present invention relates to modified and pulsatile release pharmaceutical formulations of escitalopram and their use for the treatment of central nervous system disorders, including mood disorders (e.g., major depressive disorder) and anxiety disorders (e.g., generalized anxiety disorder, social anxiety disorder, post traumatic stress disorder, and panic disorder, including panic ... 06/14/07 - 20070134321 - Pharmaceutical tablets with height greater than width Described is a compressed multiple layer pharmaceutical tablet that has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after compression has been ... 06/14/07 - 20070134320 - Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions A composition and treatment regimen for the amelioration of epidermal herpetic lesions caused by Herpes Simplex Virus (HSV-1) symptoms, Herpes Zoster, and Herpes Genitalia. The treatment includes a regimen of oral administration of a composition including from about 15 to 50 mg of zinc sulfate, from about 5 to 20 ... 06/14/07 - 20070134319 - Pharmaceutical formulations of bisphosphonates A pharmaceutical formulation comprising an oral dosage form containing a bisphosphonic acid or a salt thereof and an inactive ingredient selected from: an ester of a medium chain fatty acid, or a lipophilic polyethylene glycol ester, said inactive ingredient having a hydrophilic lipophilic balance (HLB) of from about 1 to ... 06/14/07 - 20070134318 - Non-tabletted, chewable, individually dosed administration forms Non-tabletted, individually dosed administration forms comprising a composition of at least one pharmaceutically active substance dissolved or dispersed within a matrix material comprising a mixture of at least 0.2% by weight of a gelatine, at least one stabilising agent and at least one water-soluble alcohol and/or water as a solvent, ... 06/14/07 - 20070134317 - Non-effervescent form of sodium naproxen comprising i.a. sodium hydrogen carbonate A non effervescent tablet of sodium naproxen, comprising a tablet core and, if desired, a sugar or film coat, wherein the tablet core, based on the weight of the tablet core, consists of 30 to 99% by weight sodium naproxen and 70 to 1% by weight auxiliary agent component comprising ... 06/07/07 - 20070128274 - Direct coating solid dosage forms using powdered materials The present invention provides a method and apparatus for dry coating solid dosage forms. The method includes the steps of placing solid dosage forms in a rotatable, electrically grounded housing, and spraying a film forming polymer powder composition into the housing during rotation thereof to form a polymer coating on ... 06/07/07 - 20070128273 - Composition containing medicine extremely slightly soluble in water and method for preparation thereof A composition containing a very low water-soluble drug, which composition is produced by treating, with a supercritical or subcritical carbon dioxide fluid, a mixture containing a very low water-soluble drug and a porous material (exclusive of a porous silica material characterized in that the material has an average pore diameter ... 05/31/07 - 20070122476 - Storage stable thyroxine active drug formulations and methods for their production This invention provides a storage-stable dosage form of a thyroxine active drug composition which exhibits an improved stability. The formulation contains a thyroxine active drug substance, an alditol, and a saccharide, and, optionally, additional pharmaceutically accepted excipients. Levothyroxine sodium is the preferred active drug substance, mannitol is the preferred alditol, ... 05/31/07 - 20070122475 - Taste masking composition A composition for delivery of a medicament that has a bitter taste and/or causes throat catch is provided. The composition contains Carbomer 934, Carbomer 971, Carbomer 974, PEG-5M or a mixture thereof in an amount sufficient to mask the bitter taste of the medicament and/or throat catch. ... 05/31/07 - 20070122474 - Pharmaceutical preparation comprising an active dispersed on a matrix The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation, an active ingredient is present essentially uniformly dispersed in an excipient matrix ... 05/31/07 - 20070122473 - Aminosugar and/or glycosaminoglycan composition having therapeutic use An embodiment of the invention provides a composition having one or more active ingredients such as an aminosugar, more particularly, glucosamine, glucosamine salt, and mixtures thereof, and a glycosaminoglycan, more particularly, chondroitin, chondroitin salts, and mixtures thereof having a therapeutic use and is stable for at least 24 months. Additionally, ... 05/31/07 - 20070122472 - Synergistic binder composition, method for making same, and tablets of an active and said binder having advantageous hardness and friability Tablets of a pharmaceutical, nutritional or vitamin active compound or composition, e.g. a poorly compressible drug are made by direct compression using a synergistic binder composition of co-processed (a) copolymer of vinylpyrrolidone (VP) and vinyl acetate (VA) and (b) microcrystalline cellulose (MCC), in a wt. ratio of (a):(b) of 1-30:99-70, ... 05/31/07 - 20070122471 - Method of improving suitability for granulation The present invention provides a granulated product having improved granulatability which contains a compound with poor wettability and a surfactant, particularly the granulated product wherein at least about 35% by weight with respect to the total weight of the product does not pass through a 100-mesh sieve, and a method ... 05/24/07 - 20070116762 - Compositions of stabilized ramipril in combination with another active agent A pharmaceutical composition comprising ramipril, another active agent, and a blending agent, wherein in the ramipril is coated by the blending agent, and wherein the blending agent is glyceryl behenate, glyceryl stearate, stearyl alcohol, macrogol stearate ether, palmitosearate, ethylene glycol, polyethylene glycol, stearic acid, cetyl alcohol, lauryl alcohol, amylopectin, poloxymer ... 05/24/07 - 20070116761 - Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of suspended particles coated with protein (which acts ... 05/24/07 - 20070116760 - Pharmaceutical compositions comprising meloxicam and methods of their preparation The present invention encompasses a method of evaluating pharmaceutical compositions of meloxicam whereby one can correlate in vitro properties to in vivo properties, and pharmaceutical compositions developed using the method. ... 05/24/07 - 20070116759 - Pharmaceutical compositions of telmisartan The present invention provides a pharmaceutical composition of telmisartan comprising a) a telmisartan compound, b) a surfactant, c) a basic agent, and d) at least one diluent wherein the composition comprises less than 25% of water soluble diluents. The telmisartan compound is preferably present from about 12.5% to about 15.5%. ... 05/24/07 - 20070116758 - Atorvastatin formulation Provided are atorvastatin compositions which reduce the effect of food on the bioavailability of atorvastatin and methods for making such compositions. Also provided are methods of reducing low density lipoprotein by administering the compositions of the invention. ... 05/17/07 - 20070110802 - Wet granulation process The present invention relates to a process of wet granulation, and specifically wet granulation of material that is susceptible to convert from anhydrous form to hydrate form. ... 05/17/07 - 20070110801 - Method for the diffusion of molecules which are insoluble in an aqueous medium and composition using said method The object of the invention is a process for diffusion of lipophilic molecules in an aqueous medium, in particular derivatives of the aryl-carboxylic family for the treatment of buccopharyngeal ailments, molecules with anti-inflammatory, anti-mycotic, central action analgesic or anti-allergic activity, characterized in that it consists in resorting to salts of ... 05/10/07 - 20070104784 - Compositions and methods of treatment comprising amoxicillin and potassium clavulante with xanthan Bacterial infections may be treated using a high dosage regimen of amoxicillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet. ... 05/10/07 - 20070104783 - Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders Bioadhesive sticker tablets which are applied directly to vaginal, rectal and/or oral mucosa are described herein. In one embodiment, the sticker tablets are applied directly to ulcers or lesions in the oral cavity. The compositions adhere immediately upon administration, swell over time, and remain adherent to the ulcer or lesion ... 05/10/07 - 20070104782 - Modified release tablet formulations with enhanced mechanical properties A method of formulating a drug in solid dosage form of a specified hardness, the drug containing at least one pharmaceutically active agent that has a pH dependent release profile, at least one non-pH dependent sustained release agent, and an effective amount of Eudragit L100-55. ... 05/03/07 - 20070098789 - Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same Organoleptically acceptable solid oral dosage formulations of ibuprofen, and methods of making and using the same, are provided. A feature of the subject formulations is that they include ibuprofen and a masking component. In certain embodiments, the masking component includes one or more of a cooling agent, an organic acid ... 05/03/07 - 20070098788 - Non-benzodiazepine hypnotic compositions Pharmaceutical compositions comprising non-benzodiazepine hypnotic drugs or their pharmaceutically acceptable salts, solvates, enantiomers or mixtures and processes for preparing the same. The invention also includes immediate release and extended release pharmaceutical compositions comprising non-benzodiazepine hypnotic drugs, useful for sleep induction and sleep maintenance. ... 05/03/07 - 20070098787 - Composition for preventing and treating varicose veins of lower extremities A preventive/therapeutic agent for varicose veins or a composition for the prevention or alleviation of symptoms relevant to varicose veins. The preventive/therapeutic agent for varicose veins or the composition for the prevention or alleviation of symptoms relevant to varicose veins each is characterized by containing eicosapentaenoic acid. ... 04/26/07 - 20070092564 - Orally distintegrating formulation and process for preparing the same An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegrate rapidly in oral cavity and be taken without aid of ... 04/26/07 - 20070092563 - Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of suspended particles coated with protein (which acts ... 04/26/07 - 20070092562 - Product and process for increasing compactibility of carbohydrates The present invention includes a method for preparing a highly compactible carbohydrate product, and the product itself. In one embodiment, a composition according to the present invention is a quick-dissolving composition that includes polyols. ... 04/26/07 - 20070092561 - Water-soluble aspirin composition Compositions in which aspirin is present in combination with alkaline compounds, especially those containing water of crystallization (hydrates), deteriorate on standing. This deterioration may take several forms: It can be a physical deterioration in which such aspirin compositions become completely unmanageable, wet, gummy, sticky masses; or chemical decomposition in which ... 04/19/07 - 20070087051 - Pharmaceutical composition A method of treating a cyclooxygenase-2 dependent disorder or condition comprising administering a solid formulation of 5-methyl-2-(2′-chloro-6′-fluoroanilino)phenylacetic acid which has a residual moisture within predetermined levels. ... 04/19/07 - 20070087050 - Orally disintegratable simvastatin tablets An orally disintegratable tablet containing simvastatin and silicified microcrystalline cellulose is provided with a non-alkaline lubricant. ... 04/12/07 - 20070082048 - Sleep aid formulations Orally dissolvable dosage forms comprising sleep aids such as benodiazepines are described. The dosage forms may be in the form of tablets or strips. In certain embodiments, the dosage forms may comprise particles, granules, microgranules, or crystals, and a matrix. The particles, granules or microgranules comprise a combination of immediate-release ... 04/12/07 - 20070082047 - Solid preparation A chewable tablet comprising a group which contains an acid-labile active ingredient and at least one basic substance selected from alkaline earth metal carbonate, metal oxide and metal hydroxide, and a group which does not contain an acid-labile active ingredient and contains at least one ingredient selected from alkaline earth ... 04/05/07 - 20070077297 - Modified release ibuprofen dosage form The present invention is a solid dosage form for oral administration of ibuprofen comprising a modified release formulation of ibuprofen which provides an immediate burst effect and thereafter a sustained release of sufficient ibuprofen to maintain blood levels at least 6.4 μg/ml over an extended period of at least 8 ... 04/05/07 - 20070077296 - Pharmaceutical preparation containing meloxicam The invention relates to novel solid formulations comprising as pharmaceutically active compound meloxicam and to processes for producing such solid formulations. The invention furthermore relates to a method for manufacturing a medicament for the prevention and/or treatment of pain, inflammation, fever, acute mastitis, diarrhoea, locomotive disorders, lameness, osteoarthritis, problems of ... 04/05/07 - 20070077295 - Method and composition for pharmaceutical product This invention is directed to a composition comprising dry granulated tenofovir DF and emtricitabine, and a method for making same. Dry granulation was unexpectedly found to be important in preparing a tenofovir DF containing composition suitable for inclusion in a combination dosage form containing emtricitabine, efavirenz and tenofovir DF. ... 03/29/07 - 20070071815 - Oral formulation of creatine derivatives and method of manufacturing same Oral formulation of creatine derivative and in particular creatine esters and more particularly ethyl esters of creatine are described. The formulations comprise a phosphate such as dicalcium phosphate, a biodegradable polymer such as a polyvinyl pyrrolidine and a starch. The formulation may further comprise other excipients such as metal salt ... 03/29/07 - 20070071814 - Vaginal tablets comprising misoprostol and methods of making and using the same The present invention is directed to vaginal tablets comprising misoprostol and a pharmaceutically acceptable pH insensitive, hydrophilic cellulose material, wherein the vaginal tablets do not contain a hydrophobic release controlling agent, and wherein the misoprostol and the pharmaceutically acceptable pH insensitive, hydrophilic cellulose material are in a ratio of about ... 03/29/07 - 20070071813 - Novel dosage formulation wherein the definitions are described in claim 1, or pharmaceutically acceptable acid addition salts thereof and a water soluble poloxamer in which the compound of formula I and the water soluble poloxamer are processed by hot melt extrusion, and then the hot melt extrudate is mixed with other ingredients to ... 03/29/07 - 20070071812 - Pharmaceutical composition containing fenofibrate and method for the preparation thereof The invention concerns a pharmaceutical composition containing micronized fenofibrate, a surfactant and a binding cellulose derivative, as solubilizing adjuvant, preferably hydroxypropylmethylcellulose. The cellulose derivative represents less than 20 wt. % of the composition. The association of micronized fenofibrate with a binding cellulose derivative, as solubilizing adjuvant and a surfactant enables ... 03/29/07 - 20070071811 - Stable combinations of amlodipine besylate and benazepril hydrochloride The present invention provides a pharmaceutical composition comprising benazepril and amlodipine wherein the benazepril and the amlodipine are in physical contact with one another, and methods for making the same. ... 03/29/07 - 20070071810 - Additive for tablets A disintegrant for tablets consisting of an α-1,4-glucan having a degree of polymerization of not less than 180 and less than 1230 and a dispersity (weight average molecular weight “Mw”/number average molecular weight “Mn”) of not more than 1.25 or a modified product thereof. A binder for tablets consisting of ... 03/22/07 - 20070065509 - Method of preparing sustained-release preparations of quinolone antibiotics The present invention relates to an orally administrable preparation comprising a quinolone antibiotic which releases the active compound with a delay. ... 03/22/07 - 20070065508 - Composition comprising vitamin b12 and acid reducing agent and uses thereof The present invention provides compositions and methods for treating or reducing the risk of a vitamin B12 deficiency in a subject having or in need of a gastrointestinal acid reduction treatment. ... 03/22/07 - 20070065507 - Bisphosphonate formulation A bisphosphonate for treatment of osteoporosis is formulated with an amount of an antifoaming agent effective for reducing foaming in the stomach, leading to reduced reflux and oesophageal irritation in use and increased patient compliance. ... 03/22/07 - 20070065506 - Keratin and soluble derivatives thereof for a nutraceutical and to reduce oxidative stress and to reduce inflammation and to promote skin health Keratin and derivatives thereof, preferably S-sulfonated keratin intermediate filament protein, S-sulfonated keratin high sulfur protein, and S-sulfonated peptides provide antioxidant activity, e.g., that equal to 200-2200 μmol TEAC/100 g or 100 ml, and are useful in an oral supplement to cause reduction in oxidative stress and benefits stemming therefrom, e.g., ... 03/22/07 - 20070065505 - Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form Solid pharmaceutical compositions and methods of their use suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically-effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions utilize micronized forms of the ... 03/15/07 - 20070059361 - Fast-disintegrating epinephrine tablets for buccal or sublingual administration Described herein are formulations for fast-disintegrating epinephrine tablets which can be prepared for buccal or sublingual administration, wherein the fast-disintegrating epinephrine tablets can produce plasma epinephrine concentrations similar to those achieved by an approximately 0.3 mg epinephrine dose in the thigh (Epi-Pen). ... 03/15/07 - 20070059360 - Water-dispersible anti-retroviral pharmaceutical compositions Provided herein are water-dispersible pharmaceutical compositions comprising a combination of one or more anti-retroviral drugs useful for the treatment of Human Immunodeficiency Virus (HIV) infections. Also provided are processes for preparing such water-dispersible pharmaceutical compositions. ... 03/15/07 - 20070059359 - Immediate-release and high-drug-load pharmaceutical formulations of non-micronised (4-chlorophenyl)[4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof The invention relates to immediate-release and high-drug-load solid pharmaceutical formulations comprising non-micronized (4-chlorophenyl)[4-(4-pyridylmethyl)-phthalazin-1-yl] as well as pharmaceutically acceptable salts thereof. ... 03/15/07 - 20070059358 - Matrix adjuvants and the drop pills prepared with them The present invention relates to the matrix adjuvants for drop pills and the preparation of the drop pills. The matrix adjuvants for drop pills of the present invention comprise new matrix adjuvants with or without the plastifying components, which are typically natural matrix adjuvants derived from plants and of safety ... 03/15/07 - 20070059357 - Adiponectin production enhancer The present invention provides a pharmaceutical composition for enhancement of adiponectin production, treatment or prevention of hypoadiponectinemia, and the like, comprising as an active ingredient an HMG-CoA reductase inhibitor. ... 03/15/07 - 20070059356 - Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen A pharmaceutical composition comprising a co-crystal of an API and a co-crystal former; wherein the API has at least one functional group selected from ether, thioether, alcohol, thiol, aldehyde, ketone, thioketone, nitrate ester, phosphate ester, thiophosphate ester, ester, thioester, sulfate ester, carboxylic acid, phosphinic acid, phosphonic acid, sulfonic acid, amide, ... 03/08/07 - 20070053978 - Process for co-spray drying liquid herbal extracts with dry silicified mcc A process for preparing dry extracts from a liquid extract and at least one additional substance by a spray-drying process, characterized in that said at least one additional substance is added to the spray-drying process in a dry form during the spray-drying processes. ... 03/08/07 - 20070053977 - Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet ... 03/08/07 - 20070053976 - Novel combination of drugs as antidepressant A novel antidepressant composition of a cholinesterase inhibitor in combination with a selective serotonin reuptake inhibitor, milnacipran or duloxetine is disclosed, which has a significantly high therapeutic effect as compared with conventional antidepressants. The therapeutic method using a cholinesterase inhibitor in combination with a selective serotonin reuptake inhibitor, milnacipran or ... 03/08/07 - 20070053975 - Ramipril formulation A Ramipril formulation rapidly disintegrates after ingestion and exhibits substantially no food effect. ... 03/08/07 - 20070053974 - Stable oral composition The present invention provides a stable oral composition comprising a therapeutically effective amount of desloratadine and a stabilizer selected from the group comprising an antioxidant, a pharmaceutically acceptable organic compound that provides an alkaline pH, an alkali metal salt, or mixtures thereof, and pharmaceutically acceptable excipients. ... 03/08/07 - 20070053973 - Amorphous antibiotic composition comprising cefditoren pivoxil According to the present invention, there is provided a solid dispersion composition which can maintain amorphous cefditoren pivoxil in a suspension for a long period of time. The present invention is a solid dispersion composition comprising at least 0.1 mg of a sugar ester fatty acid on the basis of ... 03/01/07 - 20070048374 - Bazedoxifene acetate formulations The present invention is directed to formulations of bazedoxifene acetate that have reduced polymorph conversion, compositions containing the same, preparations thereof, and uses thereof. ... 03/01/07 - 20070048373 - Dried milled granulate and methods The present invention relates to a method of producing a dried wet granulate having a desirable average particle size and particle size distribution and dosage forms made from that granulate. ... 03/01/07 - 20070048372 - Method for treating non-inflammatory osteoarthritic pain A method for treating non-inflammatory osteoarthritic pain in a subject comprises administering to the subject a compound as defined herein, illustratively lacosamide, or a pharmaceutically acceptable salt thereof. ... 03/01/07 - 20070048371 - Pharmaceutical formulations/composition of guanfacine suitable for single dose form administration daily Therapeutic formulations of guanfacine in a once a day single dose form which have useful overall tablet sizes are disclosed. ... 03/01/07 - 20070048370 - Pharmaceutical formulation for salts of monobasic acids with clopidogrel A pharmaceutical formulation in the form of a tablet which contains, as active substance, a salt of a monobasic acid with clopidogrel is disclosed herein. ... 03/01/07 - 20070048369 - Mucosal delivery tablet Mucoadhesive tablets have a convex surface, a diameter to cup depth ratio of 4-20 and a cup depth to edge thickness ratio of greater than 0.75 swiftly adheres and conforms to the contacting tissue. The tablets are used to administer actives such as, for example, benzocaine. ... 02/22/07 - 20070042039 - Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet ... 02/22/07 - 20070042038 - Progestin co-micronized with a surfactant, pharmaceutical composition comprising same, methods for making same and uses thereof The invention concerns a progestin co-micronized with a surfactant and a pharmaceutical composition comprising said gestagenic. The invention also concerns methods for preparing same. ... 02/15/07 - 20070036854 - Therapeutic applications of pro-apoptotic benzodiazepines wherein R1, R2, R3 and R4 are as defined. The invention also includes enantiomers, pharmaceutically acceptable salts, prodrugs or derivatives of the benzodiazepine compounds. Any one or more of these benzodiazepine compounds can be used to treat a variety of dysregulatory disorders related to cellular death. Such disorders include autoimmune ... 02/15/07 - 20070036853 - Generally linear effervescent oral fentanyl dosage form and methods of administering Fentanyl containing dosage forms and methods using same are described. These dosage forms include substantially less fentanyl by weight than know oral formulation and have advantages in terms of cost and side effects. These dosage forms are intended for oral administration of fentanyl across the oral mucosa. ... 02/15/07 - 20070036852 - Rapidly dispersing/disintegrating compositions The present invention relates to a rapidly dispersing/disintegrating, taste masked oral ondansetron dosage forms and a simple and economic process for their manufacture which can be easily scaled up. In particular, the present invention relates to a compressed dosage form for oral administration capable of being rapidly disintegrated comprising a ... 02/15/07 - 20070036851 - Acid labile drug compositions A composition and method of making a pharmaceutical dosage form containing an acid labile drug bound to an ion exchange resin is provided. The composition may be coated with a low acid content enteric coating. The binding of the acid labile drug to the exchange resin stabilizes the drug against ... 02/08/07 - 20070031489 - Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness The present invention relates to methods for reducing the risk associated with the administration of opioid analgesics in patients diagnosed or undiagnosed with respiratory illness by administering an analgesic composition comprising a sub-analgesic dosage of a p-opioid agonist selected from the group consisting of morphine, fentanyl, sufentanil, alfentanil, oxymorphone and ... 02/08/07 - 20070031488 - Method of administering a partial dose of a segmented pharmaceutical tablet A drug-containing pharmaceutical tablet adapted for accurate breaking which has two or more segments with at least one segment containing a drug. ... 02/01/07 - 20070026064 - Pharmaceutical dosage forms having watermark-type identification and authentication inditia Oral solid dosage forms having holographic markings or identification marks such as a watermark thereon and methods of preparing the same are disclosed. One preferred method of applying an identification mark on a pharmaceutical dosage form described herein includes applying a film coating having a first color to an oral ... 02/01/07 - 20070026063 - Composition for coating comprising low-substituted cellulose ether and coated preparation having unpleasant taste masked The present invention is a composition for coating comprising a wet-milled product obtained by suspending low-substituted cellulose ether having a molar substitution of from 0.05 to 1.0 per anhydrous glucose unit in water and then applying a shear force to the aqueous dispersion. The present invention is also a coated ... 01/25/07 - 20070020332 - Tannate compositions, methods of making and methods of use Tannate compositions containing active pharmaceutical ingredients to be used for treating nausea, vomiting, pain, convulsions, and insomnia and manufacturing processes for preparing the tannate compositions. ... 01/25/07 - 20070020331 - Coated tablet with zero-order of near zero-order release kinetics Tablets for the controlled release of an active ingredient in a zero-order or near zero-order fashion are provided. The tablet includes a core and a coating. The core includes at least one active pharmaceutical agent and a polyethylene oxide with a molecular weight of between about 1,000,000 and 10,000,000, preferably ... 01/25/07 - 20070020330 - Compositions comprising azelastine and methods of use thereof The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize ... 01/25/07 - 20070020329 - Methods of formulating linezolid A method of formulating linezolid to provide a pharmaceutical composition comprising linezolid wherein the linezolid is linezolid Form IV substantially free of linezolid Form II, a solid pharmaceutical composition comprising linezolid Form IV substantially free of linezolid Form II and povidone, methods of treating a condition responsive to linezolid in ... 01/18/07 - 20070014857 - Pharmaceutical formulation having a masked taste and method for the production thereof The invention relates to a pharmaceutical formulation in the form of a powder which is administered orally in an aqueous suspension, having a masked taste, and comprising at least one cellulose polymer, a methacrylic polymer and an active ingredient which is distributed in a homogeneous manner in a molecular state ... 01/18/07 - 20070014856 - Rapidly disintegrable pharmaceutical composition The present invention relates to a pharmaceutical composition useful for rapid disintegration, which comprises a sparingly soluble medicament held on a gel-forming water-soluble polymer as a solid dispersion, wherein it contains a salt substance that comprises an alkali and a weak or strong acid and has an endothermic standard enthalpy ... 01/18/07 - 20070014855 - Stable desloratadine compositions Stable pharmaceutical compositions of desloratadine or pharmaceutically acceptable salts in combination with one or more therapeutically active compounds. ... 01/18/07 - 20070014854 - Novel granulation process One of the objects of the invention relates to a pharmaceutical composition in the form of a granulate, wherein the granulates comprises an active pharmaceutical ingredient (API) having a poor water solubility intimately associated with at least one pharmaceutically acceptable sugar, and optionally or preferably at least one pharmaceutically acceptable ... 01/18/07 - 20070014853 - Pharmaceutical dosage form containing novel pharmaceutical granulate One of the objects of the invention relates to a pharmaceutical composition in the form of a granulate, wherein the granulates comprises an active pharmaceutical ingredient (API) having a poor water solubility intimately associated with at least one pharmaceutically acceptable sugar, and optionally or preferably at least one pharmaceutically acceptable ... 01/18/07 - 20070014852 - Tablets having a printed separation mark to guide breaking The invention provides a novel “separation marking” on a tablet as a means for assisting in the identification of a region on the tablet that is desired to be able to be broken from time to time. Said breaking allows production of smaller dosage forms known herein as tablettes. In ... 01/18/07 - 20070014851 - Solid pharmaceutical preparation containing levothyroxine and/or liothyronine salts In a solid pharmaceutical preparation containing water-soluble salts of levothyroxine and/or liothyronine as active ingredients, the water activity of said pharmaceutical preparation is adjusted to values of below 0.4 and, preferably, 0.1 to 0.3, measured at room temperature. ... 01/18/07 - 20070014850 - Process for the preparation of dispersible tablets of cephalexin The present invention relates to dispersible tablets of cephalexin and a process for their preparation. ... 01/11/07 - 20070009595 - Sugar alcohol composition for tableting A powdery sugar alcohol composition which is useful as a tableting excipient is provided. The composition of the invention consists essentially of a crystalline sugar alcohol and an amorphous sugar alcohol, provided that the composition comprises 2-12 wt % of amorphous sorbitol. By employing the sugar alcohol composition as tableting ... 01/11/07 - 20070009594 - Compositions and methods for treatment of cycle-related symptoms Methods are provided for treating cycle-related symptoms through administration of at least one progestin and at least one estrogen to a female subject. ... 01/11/07 - 20070009593 - Methods of treating cancer Methods for treating cancer are described herein. The methods include administering to an HIV-negative patient an m-calpain inhibitor such as ritonavir. Ritonavir or other m-calpain inhibitors can also be co-administered with other therapeutic agents such as a Cox-2 inhibitor, a taxane, or a proteasome inhibitor. Methods for determining whether a ... 01/11/07 - 20070009592 - Immediate release pharmaceutical granule compositions and a continuous process for making them An immediate or fast release pharmaceutical granule composition comprising at least one drug (i) classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein the said drug constitutes at least about 0.5% by weight and no more than 50% by weight of the composition, and further comprising ... 01/11/07 - 20070009591 - Ace inhibitor formulation A process for preparing pharmaceutical micro-tablets comprises (a) preparing a tableting mix that comprises an ACE inhibitor, for example moexipril hydrochloride, and excipient ingredients that comprise one or more lubricants; and (b) compressing the tableting mix in a tablet press, to form micro-tablets having an average uncoated weight of about ... 01/11/07 - 20070009590 - Physiologically active composition based on phosphatidylserine This physiologically active composition contains, as physiologically active constituents, the components a) phosphatidylserine and/or lysophosphatidylserine (in each case “PS”) and b) at least one (lyso)phospholipid different from component a) and c) a serine source different from component a), for example L-serine and/or O-phospho-L-serine. In this composition, the components a) and ... 01/04/07 - 20070003616 - Process for the production of an abuse-proofed dosage form The present invention relates to a process for the production of abuse-proofed, thermoformed dosage forms containing, apart from one or more active ingredients with potential for abuse and optionally physiologically acceptable auxiliary substances, at least one synthetic or natural polymer with a breaking strength of at least 500 N. ... 01/04/07 - 20070003615 - Nanoparticulate clopidogrel and aspirin combination formulations The present invention is directed to compositions comprising a nanoparticulate clopidogrel and aspirin combination, or salts or derivatives thereof, having improved clopidogrel bioavailability. The nanoparticulate clopidogrel particles, and optionally the nanoparticulate aspirin particles, of the composition have an effective average particle size of less than about 2000 nm and are ... 12/28/06 - 20060292220 - Compositions and methods for nutrition supplementation The present invention relates to compositions that may be swallowable, chewable or dissolvable, comprising various vitamins and minerals, and in a specific embodiment comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and methods for using these compositions for nutritional supplementation in ... 12/28/06 - 20060292219 - Sublingual buccal effervescent A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional ... 12/28/06 - 20060292218 - Agent having a destructive effect on malignant tumors and method for the production thereof Disclosed is an agent which has a destructive effect on malignant tumors and contains alpha-ketoglutaric acid, N-acetyl-seleno-L-methionine, N-acetyl-L-methionine, and a compound that is capable of forming azomethine and is selected among the group 5-hydroxymethylfurfural, dehydroascorbic acid, maltol, and vanillin as an active substance, 5-hydroxymethylfurfural being preferred. The inventive agent can ... 12/21/06 - 20060286167 - Compositions and methods for the treatment of neurodegenerative diseases The invention features compositions and methods for the treatment of neurodegenerative diseases. ... 12/21/06 - 20060286166 - Tadalafil having a large particle size and a process for preparation thereof The present invention provides particulate tadalafil having a particle size of about 200 to about 600 microns and a process for controlling the particle size of tadalafil. ... 12/21/06 - 20060286165 - Taste-masked pharmaceutical particle, the preparation and use thereof The present invention provides a taste-masked pharmaceutical particle prepared by a polymer blending process, a process for preparing the particle, and the use of the particle in preparing the orally disintegrating tablets. In this process, a micronized active drug ingredient is mixed with three kinds of pharmaceutically acceptable polymer adjuvants ... 12/14/06 - 20060280792 - Attachment of a handle to a solid oral dosage form The present invention relates to a method of attaching a handle to a solid oral dosage form by use of high frequency mechanical vibrations. The present invention also relates to a method of attaching a handle to a solid oral dosage form, the method comprising: (a) placing a handle in ... 12/14/06 - 20060280791 - Pharmaceutical formulations The present invention relates to oral formulations comprising an active agent comprising at least one of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, salts of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid or buffered 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid. ... 12/14/06 - 20060280790 - Pharmaceutical formulations The present invention relates to oral formulations comprising an active agent comprising at least one of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, salts of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid or buffered 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid. ... 12/14/06 - 20060280789 - Sustained release formulations The invention provides sustained release formulations of basic drugs, stereoisomers of basic drugs, pharmaceutically acceptable salts of basic drugs, and pharmaceutically acceptable salts of stereoisomers of basic drugs. The basic drugs may be anti-dementia drugs, such as cholinesterase inhibitors or memantine. In one embodiment, the cholinesterase inhibitor is donepezil. ... 12/07/06 - 20060275365 - Immediate-release and high-drug-load pharmaceutical formulations of micronised (4-chlorophenyl) [4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof The invention relates to immediate-release and high-drug-load solid pharmaceutical formulations comprising micronised (4-chlorophenyl)[4-(4-pyridylmethyl)-phthalazin-1-yl] as well as pharmaceutically acceptable salts thereof. ... 12/07/06 - 20060275364 - Flexible solid dosage forms and methods of making and using the same The present invention provides flexible solid dosage forms that include an active agent, gelatin, and a polyol or saccharide. The present invention also provides methods of making flexible solid dosage forms. ... 12/07/06 - 20060275363 - Stable granulates containing s-adenosylmethionine and process for preparation thereof A fluid bed granulation process for manufacturing non-hygroscopic, stable granulates containing a water-soluble salt of S-adenosylmethionine is described. Said process comprises: a) the simultaneous, sequential or alternate dispersion of at least a solution of a water-soluble salt of SAMe (A) and of a solution of a coating agent (B), on ... 12/07/06 - 20060275362 - Rapidly-dissolving pharmaceutical composition for inhibiting ovulation A rapidly-dissolving oral dosage pharmaceutical composition for inhibiting ovulation in a mammal, said composition comprising drospirenone or a pharmaceutically acceptable salt or ester thereof, optionally ethinyl estradiol or a pharmaceutically acceptable salt, ester or ether thereof, a surfactant and at least one pharmaceutically acceptable excipient, wherein the drospirenone has a ... 11/30/06 - 20060269600 - Oral dosage form containing a pde 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient Dosage forms for oral administration of a PDE4 inhibitor whose solubility is slight are described. They contain PVP as a binder. ... 11/30/06 - 20060269599 - Fast-dissolving pharmaceutical composition A fast-dissolving pharmaceutical composition comprising micronized (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3′-pyrrolidine-1,2′,3,5′-tetrone (hereinafter, referred to as AS-3201). The present pharmaceutical composition has improved dissolution characteristics as well as a good bioavailability. ... 11/23/06 - 20060263425 - Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent A pharmaceutical composition, which composition comprises: an insulin sensitiser and another antidiabetic agent and a pharmaceutically acceptable carrier therefor, wherein the composition is arranged to provide a modified release of at least one of the insulin sensitiser and the other antidiabetes agent, and the use of such composition in medicine. ... 11/23/06 - 20060263424 - Pharmaceutical compositions comprising clavulanic acid A pharmaceutical composition comprising an active ingredient and clavulanate wherein the clavulanate is in the form of granulated and hydrophobised particles; and intermediates in its preparation, e.g. clavulanate in granulated and/or hydrophobised form. ... 11/23/06 - 20060263423 - Product and process for increasing compactibility of carbohydrates The present invention includes a method for preparing a highly compactible carbohydrate product, and the product itself. In one embodiment, a composition according to the present invention includes polyols. ... 11/16/06 - 20060257478 - Acid-gas absorbing tablet and method of use An acid-gas absorbing tablet including in relatively sufficient proportions an adsorbent which may be activated carbon or silica gel or a mixture thereof, potassium carbonate, polyvinylpyrrolidinone, and potassium bicarbonate. A method of absorbing acid gases from a confined environment utilizing the above tablet by inserting it into the confined environment. ... 11/16/06 - 20060257477 - Acid-gas absorbing tablet and method of use An acid-gas absorbing tablet including in relatively sufficient proportions an adsorbent which may be activated carbon or silica gel or a mixture thereof, potassium carbonate, polyvinylpyrrolidinone, and potassium bicarbonate. A method of absorbing acid gases from a confined environment utilizing the above tablet by inserting it into the confined environment. ... 11/16/06 - 20060257476 - Tablet formulation Disclosed is a non-sustained release pharmaceutical tablet composition which comprises a rapidly precipitating drug in an amount from about 5 to about 60% and at least one member selected from the group consisting of a binder in an amount of from about 2 to about 25% and a superdisintegrant in ... 11/16/06 - 20060257475 - Stable sertraline hydrochloride formulation and method Pharmaceutically stable solid pharmaceutical dosage forms of sertraline hydrochloride Form II and Form V polymorphs formed by direct compression. ... 11/16/06 - 20060257474 - Remedies for glomerular diseases The present invention relates to a preventive or therapeutic agent for a glomerular disease which comprises an anti-thrombocytic agent and an HMG-CoA reductase inhibitor as active ingredients. The above agent is useful for prevention and therapy of various glomerular diseases including chronic glomerular nephritis. ... 11/16/06 - 20060257473 - Extended release tablet A single tablet layer having an extended release profile comparable to the release profile of a bi-layer tablet having both an immediate release and an extended release layer is prepared from a pharmaceutical granulation containing a pharmaceutically active compound, a hydrophilic polymer, and a water in-soluble, non-swellable particulate channeling agent. ... 11/16/06 - 20060257472 - Stability of progestogen formulations In a preparation for hormone replacement therapy having a low content of progestogen, the stability of the progestogen component can be enhanced by using a cellulosic binder, for example hydroxypropylcellulose, in stead of a non-cellulosic binder. ... 11/16/06 - 20060257471 - Pharmaceutical tablets of crystalline type ii aripiprazole Crystalline aripiprazole Type II can be formulated into pharmaceutical tablets having reduced dissolution profile variability upon storage. ... 11/16/06 - 20060257470 - Method for producing solid galenic formulations using a crosslinked non-thermoplastic carrier The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols and solubilizing ... 11/09/06 - 20060251718 - Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby A pharmaceutical formulation of compounds with low aqueous solubility and method of manufacture thereof. The formulation may include a pharmacologically active compound having low aqueous solubility and starch in the amount of greater than about 25 weight percent. A manufacturing method may include blending the active compound and starch, compressing ... 11/09/06 - 20060251717 - Memantine oral dosage forms This invention relates to an oral dosage form containing between 1 mg and 100 mg of memantine, wherein said dosage form does not contain 10 mg of memantine or 20 mg of memantine, and wherein said dosage form is not prepared by the patient or a person administering the drug ... 11/09/06 - 20060251716 - Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms The present invention comprises a co-processed carbohydrate system, and formulations produced therefrom, which formulations are directly compressible into solid dosage forms, some of which rapidly and completely dissolve or disintegrate in the oral cavity within 60 seconds. The invention also comprises the solid dosage forms produced by directly compressing the ... 11/09/06 - 20060251715 - Oral delivery of a botanical A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted ... 11/09/06 - 20060251714 - Pharmaceutical formulations of amyloid inhibiting compounds Therapeutic formulations and methods for inhibiting amyloid deposition in a subject, whatever its clinical setting, are described. Therapeutic formulations and methods for preventing or treating amyloidosis and/or amyloid-related disease are also described. ... 11/02/06 - 20060246131 - Use of metformin to counteract weight gain associated with psychotropic medications A method for minimizing the weight gain side effect associated with ABILIFY® (aripiprazole) or GEODON® (ziprasidone) treatment is disclosed. In this method, metformin, a biguanide compound, is concurrently administered to a patient taking the ABILIFY® (aripiprazole) or GEODON® (ziprasidone) therapy. A pharmaceutical composition containing the combination of ABILIFY® (aripiprazole) or ... 11/02/06 - 20060246130 - Compositions and methods for combination antiviral therapy The present invention relates to therapeutic combinations of [2-(6-amino-purin-9 yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R,5S,cis)-4-amino-5-fluoro-1-(2 hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine, Emtriva™, (−)-cis FTC) and their physiologically functional derivatives. The combinations may be useful in the treatment of HIV infections, including infections with HIV mutants bearing resistance to nucleoside and/or ... 10/26/06 - 20060240102 - Binders for tablets with high strength based on finely divided vinyllactam polymers, the production and use thereof Finely divided binders in powder form composed of vinyllactam polymers, where the binders have an average particle size of up to 35 μm and an apparent density of less than 0.2 g/ml. ... 10/26/06 - 20060240101 - Orally disintegrating pharmaceutical tablet formulations of olanzapine This invention provides orally disintegrating pharmaceutical tablet formulations comprising per tablet the following ingredients in the following percentages by weight: olanzapine as an active ingredient in an amount from about 2.5% to about 10%; mannitol in an amount from about 75% to about 95%; a disintegrating agent in an amount ... 10/26/06 - 20060240100 - Dosage form containing pantoprazole as active ingredient Dosage forms for the oral administration of the magnesium salt of pantoprazole are described. ... 10/19/06 - 20060233876 - Compositions and methods for reducing cardiovascular morbidity and/or mortality The present invention is related to a method for reducing cardiovascular morbidity and/or mortality comprising administering a combination comprising an ACE inhibitor and a CCB, specifically benazapril and amlodipine besylate. ... 10/19/06 - 20060233875 - Taste masked sumatriptan tablets and processes for their preparation The technical field of the present invention relates to uncoated, taste masked sumatriptan tablets for oral administration and processes for their preparation. It also relates to wax polished sumatriptan tablets and processes for their preparation. ... 10/12/06 - 20060228411 - Pharmaceutical compositions having improved dissolution profiles for poorly soluble drugs Pharmaceutical compositions having improved dissolution profiles for drugs therein is disclosed. ... 10/12/06 - 20060228410 - Flavored taste-masked pharmaceutical formulation made using a one-step coating process The present invention encompasses a flavored and taste-masked pharmaceutical composition comprising a plurality of pharmaceutically acceptable cores, such as microspheres, said pharmaceutically acceptable cores comprising etoricoxib, wherein the pharmaceutically acceptable cores are coated with a flavored taste-masking coating solution in a convenient one-step process. ... 10/12/06 - 20060228409 - Scored tablet An object of the present invention is to provide a dividable tablet that is easily and accurately divided without any particular limitation on dividing method thereof and has superior strength. That is, the present invention provides a dividable tablet whose lower surface is a curved surface gradually rising from the ... 10/05/06 - 20060222707 - Formulations of fenofibrate The invention provides at least a composition for the treatment of elevated levels of triglycerides, comprising a therapeutically effective amount of a fibrate drug, preferably fenofibrate, intimately associated with a surfactant mixture, preferably a mixture comprising PGE 6000 and poloxamer 407. The invention also provides a method for the treatment ... 10/05/06 - 20060222706 - Formulations of fenofibrate The invention provides at least a composition for the treatment of elevated levels of triglycerides, comprising a therapeutically effective amount of fenofibrate or another fibrate drug intimately associated with menthol or a surfactant mixture, wherein the menthol can be menthol or menthol surfactant mixture, and wherein the surfactant mixture can ... 10/05/06 - 20060222705 - Pharmaceutical tablet and apparatus and method for making A punch and die set include a die with a single large cavity which can receive dry particles of relatively large dimensions or large arching indexes as compared to the transverse dimensions of the tablets formed by the particles, e.g., 1.5 mm diameter and 1 mm height. The upper and ... 10/05/06 - 20060222704 - System and a method for labeling a substrate A method for labeling a substrate includes positioning the substrate adjacent to an inkjet material dispenser, and selectively jetting an edible ink onto the substrate with the inkjet material dispenser. The edible ink is configured to exhibit a known fluorescent emissive profile when exposed to a visible light. ... 10/05/06 - 20060222703 - Pharmaceutical composition and preparation method thereof The invention relates to an oral solid pharmaceutical composition comprising pharmacologically effective amounts of entacapone, levodopa and carbidopa, or a pharmaceutically acceptable salt or hydrate thereof, and one or more pharmaceutically acceptable excipients, wherein the excipients are long-chain polymers having an equilibrium moisture content of at least 2%, and to ... 10/05/06 - 20060222702 - System and method for optically tracking objects using a spectral fingerprint of fluorescent compounds A method for labeling a substrate includes positioning the substrate adjacent to an inkjet material dispenser, and selectively jetting an edible ink onto the substrate with the inkjet material dispenser. The edible ink is configured to exhibit a known fluorescent emissive profile when exposed to an ultraviolet light. ... 09/28/06 - 20060216349 - Ibuprofen composition Fumaric acid is added in amounts sufficient to reduce the burn sensation commonly associated with propionic acid derivatives. ... 09/28/06 - 20060216348 - Agglomerated starch compositions Agglomerated starch compositions containing native starch and pre-compacted starch powder is disclosed. The agglomerated starch compositions have superior flow and less pH sensitivity than simple blends of the two components at equivalent ratios. ... 09/28/06 - 20060216347 - Tablet punches and methods for tableting A tablet punch having a punch cup having a non-stick polymeric coating which may comprise a fluoropolymer such as polytetrafluoroethylene. ... 09/28/06 - 20060216346 - Dosage form containing (s)-pantoprazole as active ingredient Dosage forms for the oral administration of the magnesium salt of (S)-pantoprazole are described. ... 09/21/06 - 20060210628 - Use of epinine for enhancing physical performance A method of decreasing fat and adipose tissue, and increasing alertness in humans comprises administering epinine in a daily dosage between about 50 and 300 mg. Epinine may be administered once per day or in multiple doses, either alone or in combination with other compounds and mixtures. ... 09/21/06 - 20060210627 - Direct compression formulation and process This invention relates to tablets especially tablets formed by direct compression of a dipeptidylpeptidase IV (DPP-IV) inhibitor compound, a process for the preparation thereof, to new pharmaceutical formulations, and new tableting powders comprising DPP-IV inhibitor formulations capable of being directly compressed into tablets. The invention relates further to a process ... 09/21/06 - 20060210626 - Radio frequency identification pharmaceutical tracking system and method An ingestible dosage form includes a pill containing a pharmaceutical content and an RF tag associated with the pill. The RF tag is configured to output a wireless response signal in response to a wireless excitation signal received by the RF tag from an RF reader. The ingestible dosage form ... 09/21/06 - 20060210625 - Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms An oral pharmaceutical composition, comprising one or more positively charged, highly water-soluble pharmaceutically active agents such as trospium chloride, and one or more polymers containing polarized oxygen atoms, whereby the active agent(s) form an ion-dipole interaction with the polymer(s) that may be used for an immediate release system, an extended ... 09/21/06 - 20060210624 - Combination product comprising an antagonist or inverse agonist of histamine receptor h<sb>3 </sb>and an antipsychotic and antidepressant agent, and use thereof for the preparation of a medicament that prevents the adverse effects of p Medicament comprising, in a pharmaceutically acceptable vehicle, an anti-psychotic or an antidepressant (A), which, on its own, has an undesirable effect of a gain in body weight or sedation, and an antagonist and/or inverse agonist (B) of the histamine H3 receptor, the antagonist and/or inverse agonist of the histamine H3 ... 09/14/06 - 20060204572 - Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives The present invention provides solid dispersions or solid dispersion pharmaceutical preparations containing a water-soluble polymeric substance(s) and a phenylalanine compound of the formula (1) or pharmaceutically acceptable salts thereof, wherein A represents the formula (2) and the like, B represent an alkoxy group and the like, E represents a hydrogen ... 09/14/06 - 20060204571 - Stable compositions of bupropion or its pharmaceutically acceptable salts A stable oral pharmaceutical composition comprising a therapeutically effective amount of bupropion or its pharmaceutically acceptable salt intimately blending with one or more compatible excipients selected from the group consisting of talc and potassium chloride, additional pharmaceutically acceptable excipients and total impurities are present in amounts from 0% to not ... 09/14/06 - 20060204570 - Preparing method for controlled released type tablet tamsulosin hcl and the tablet thereof The present invention relates to a simple and effective method for preparing a tamsulosin HCl sustained-release tablet and a tamsulosin HCl sustained-release tablet produced thereby. The method comprises the steps of: dissolving tamsulosin HCl as an active ingredient in an organic solvent; dissolving the tamsulosin HCl solution in hydroxypropylmethylcellulose phthalate ... 09/14/06 - 20060204569 - Functional starch powder Functional starch powder of 400% or more water retention capacity, 5 hr or more collapse time and 200 g or more gel indentation load. This functional starch powder is produced through the step of heating a starch raw material in the presence of water at 60 to 150° C. so ... 09/14/06 - 20060204568 - Oral pharmaceutical preparation for proton pump antagonists The invention relates to novel dosage forms for proton pump antagonists. ... 09/07/06 - 20060198885 - Oral pharmaceutical composition An oral pharmaceutical composition having reduced bitterness comprising therapeutically effective amounts of cetirizine or its pharmaceutically acceptable salts, alkaline earth oxide and a pharmaceutically acceptable carrier comprising a disintegrant wherein the composition disintegrates rapidly in the oral cavity. ... 09/07/06 - 20060198884 - Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is released at a dissolution rate of more than about 80% within about the first 60 minutes following ... 08/31/06 - 20060193910 - Tablets with improved drug substance dispersibility The present invention relates to a method for the preparation of pharmaceutical compositions in the form of tablets with improved drug substance dispersibility, which method comprises a) preparing a dispersion of at least one pharmaceutically active drug substance and at least one surfactant and/or binder in a liquid; b) preparing ... 08/31/06 - 20060193909 - Breath freshening pressed tablets and methods of making and using same A confectionery product comprises a pressed tablet made from a compressible composition and having at least one abrasive surface suitable for cleaning the surface of a human tongue in an oral cavity. Typically the product has a first side and a second side generally opposite to the first side; the ... 08/31/06 - 20060193908 - Extended release formulations of poorly soluble antibiotics An extended release pharmaceutical compressed composition and dosage form comprising poorly water soluble macrolide antibiotic, surfactant and non-lipophilic, non-polymeric excipient is disclosed. The composition releases the macrolide antibiotic over an extended period of time, generally at least over 12 hours, even in the absence of a release rate-retarding polymer, release ... 08/24/06 - 20060188571 - Vaginally administrable progesterone containing tablets and method for preparing the same The present invention provides a method for preparing a tablet for the vaginal administration of progesterone for systemic use. The method comprises first mixing water with micronized progesterone, the total amount of water mixed with said micronized progesterone not exceeding the maximum wetting capacity of the micronized progesterone, drying the ... 08/24/06 - 20060188570 - Compressed tablet formulation This invention relates to a 50% drug loaded compressed tablet formulation for efavirenz. Efavirenz is a non-nucleoside reverse trancriptase inhibitor being studied clinically for use in the treatment of HIV infections and AIDS. ... 08/24/06 - 20060188569 - Stable pharmaceutical formulations of zonisamide and methods for their manufacture One of the embodiments of the present invention is directed toward a process for preparing a stable zonisamide pharmaceutical composition, comprising subjecting zonisamide to wet granulation with a granulation liquid to form a granulated mixture as the stable zonisamide pharmaceutical composition, wherein the granulation liquid is selected from purified water, ... 08/24/06 - 20060188568 - Stable formulations of ace inhibitors and methods for preparation thereof Stabilized pharmaceutical solid composition of ACE inhibitor comprising an ACE inhibitor and a selective dosage formulation thereof comprising of meglumine. The ACE inhibitor selectively combined with a dosage form including essentially the meglumine is surprisingly found to avoid the degradation of ACE inhibitor by such dosage forms especially the commonly ... 08/17/06 - 20060182802 - Rapidly disintegrable solid preparation A rapidly disintegrable solid preparation which comprises (i) a pharmacologically active ingredient, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group. The rapidly disintegrable solid preparation has fast disintegrability, suitable strength and no roughness. ... 08/17/06 - 20060182801 - Sequestered antagonist formulations Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is administered intact, such that the ratio of the mean Cmax of the antagonist after single dose oral administration of the ... 08/17/06 - 20060182800 - Novel pharmaceutical compositions for antihistaminic-decongestant combination and method of making such compositions The present invention relates to pharmaceutical compositions of antihistamine-decongestant combination. Specifically the invention relates to bilayered tablet formulation comprising antihistaminic decongestant combination. More specifically present invention relates to the novel polymorph of fexofenadine or pharmaceutically accepted salts thereof, with at least one decongestant in the form of bilayered tablet. The ... 08/17/06 - 20060182799 - Tabletting process The invention refers to a process for the preparation of a self-dispersing or self-emulsifying tablet, wherein a heated granulation mixture containing an active lipophilic substance and a surfactant is granulated into granules, said granules are cooled to a semi-solid state, said semi-solid granules are mixed with one or more fillers ... 08/10/06 - 20060177504 - Combination pain medication This patent is an evolution of previous combination medication patents. Previous combination patents such as U.S. Pat. No. 6,613,354 which is a combination of an NSAID and Proton Pump Inhibitor. Thus the previous patents have covered gastrointestinal prophylaxis but none has covered both gastrointestinal and cardiovascular prophylaxis. This is likely ... 08/10/06 - 20060177503 - Bambuterol and integrin inhibitor combination and treatment method The present invention provides novel solid pharmaceutical dosage forms for oral administration comprising a therapeutically active amount of bambuterol, or a pharmaceutically acceptable salt thereof, a therapeutically effective amount of N-(2-chloro-6-methylbenzoyl)-4-[(2,6-dichlorobenzoyl)amino]-L-phenylalanine-2-(diethylamino)ethyl ester, or a pharmaceutically acceptable thereof, and one or more pharmaceutically acceptable excipients. These novel solid pharmaceutical dosage forms ... 08/10/06 - 20060177502 - Sustained release pharmaceutical formulations Disclosed are novel ranolazine sustained release pharmaceutical formulations. ... 08/10/06 - 20060177501 - Film coated tablets containing ibuprofen The invention relates to film-coated tablets containing ibuprofen lysinate with improved stability, bioavailability and h |