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Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form > Web, Sheet Or Filament Bases; Compositions Of Bandages; Or Dressings With Incorporated Medicaments > Bandages With Incorporated Medicaments > Transdermal Or Percutaneous Transdermal Or PercutaneousTransdermal Or Percutaneous patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.07/19/07 - 20070166365 - Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl Silicone adhesive formulations are provided, in which fentanyl particles are suspended one or more a solvated silicone adhesives. The formulations can be used for manufacturing improved, matrix-type transdermal devices for administering fentanyl. ... 07/19/07 - 20070166364 - Transdermal therapeutic system This present invention concerns a cover layer that is impermeable to the active substances and/or a removable protective layer of a transdermal therapeutic system, comprising a thermoplastic film which either directly contains the absorbing agents and channel-forming agents or is coated with a polymer support (thermoplast) containing these substances. The ... 07/19/07 - 20070166363 - Use of cholinesterase inhibitors for treating vascular depression The invention discloses the use of cholinesterase inhibitors in treating vascular depression. ... 07/19/07 - 20070166362 - Transdermal and transmucosal preparations Transdermal and transmucosal preparations are often insufficiently absorbed. Thus, there is a need for additives that can enhance the transdermal and/or transmucosal absorption of various drugs. The present invention provides compositions for enhancing transdermal and/or transmucosal absorption, comprising a hydroxyapatite and essential ingredients. The hydroxyapatite has a maximum particle size ... 07/05/07 - 20070154536 - Drug delivery method by enhanced topical application Methods for enhancing penetration of compounds/drugs into an animal or human through their hair follicles are provided. The methods employ topical application of swellable compositions which can maintain a passage for desired drugs by either opening hair follicles and preventing them from collapsing or increasing the depth of inner lumen ... 07/05/07 - 20070154535 - Tulobuterol adhesive patch The present invention provides a tulobuterol adhesive patch comprising (a) a support, (b) an acrylic pressure-sensitive adhesive layer containing the percutaneously absorbing drug tulobuterol and if necessary a lipophilic oily plasticizer, and (c) a release liner, laminated in that order, wherein the acrylic pressure-sensitive adhesive is a copolymer obtained by ... 07/05/07 - 20070154534 - Use of secretin in the treatment of schizophrenia The treatment of schizophrenia by administration of secretin to a patient in need thereof is disclosed. ... 06/28/07 - 20070148219 - Liposomal nanowater-containing patch-type nanodermal gel for transdermal delivery and method for preparing the same Disclosed herein is a patch-type nanodermal gel including liposomal nanowater, which can deliver cosmetically active substances, such as those functioning to moisturize the skin, into and through the skin stably and effectively. The patch-type cosmetic composition for transdermal deliver, based on nanodermal gel, comprises nanowater in an amount from 0.01 ... 06/28/07 - 20070148218 - Olanzapine containing transdermal drug delivery compositions The invention features compositions for the transdermal administration of olanzapine. The compositions include olanzapine or a pharmaceutically acceptable salt thereof, a pressure sensitive adhesive, and an excipient, such as a permeation enhancer and/or a solubilizer of olanzapine. The compositions are useful for the treatment of certain psychiatric disorders, for example ... 06/28/07 - 20070148217 - Percutaneous absorption type cerebral protective agent or a medically acceptable salt thereof in a base; a use of the compound as an active ingredient for the manufacture of a percutaneous absorption type pharmaceutical composition for protecting brain; and a method of protecting brain comprising administering to a patient the pharmaceutical composition as an active ingredient, ... 06/28/07 - 20070148216 - External preparation for percutaneous administration containing nonsteroidal anti-inflammatory analgesic An external preparation for percutaneous administration which contains a light-sensitive nonsteroidal anti-inflammatory analgesic and a UVA-shielding agent which inhibits the analgesic to cause light toxicity and a light allergy. This external preparation for percutaneous administration, which contains a nonsteroidal anti-inflammatory analgesic, can be prevented, with higher certainty, from causing the ... 06/21/07 - 20070141132 - Human growth hormone patch formulations The invention encompasses a transdermal patch formulation comprising hGH, at least one sugar, one amino acid or polyol, and a buffer, wherein the buffer maintains the pH of the formulation in the range of about 5 to about 9 and the formulation does not contain both glycine and mannitol. ... 06/14/07 - 20070134311 - External preparation An external preparation having excellent percutaneous absorption ability for ionic drugs is provided. An external preparation which comprises the following components (a) and (b); component (a): an ionic drug, component (b): an ionic liquid containing a cation and an anion. By this construction, the ionic liquid functions as a solubilizing ... 06/14/07 - 20070134310 - Transdermal risperidone delivery system A system for transdermal delivery of risperidone to an individual. The system has a high risperidone loading with suitable permeation enhancers to effect therapeutic flux rate. Acrylate polymeric reservoir with the high risperidone and permeation enhancers dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties. ... 06/14/07 - 20070134309 - Agent containing ergoline for transdermal application The invention relates to a transdermal therapeutic system containing ergolin compounds, preferably lisuride, in which the ergolin compound is stabilized. The oxidation-sensitive ergolin compound is stabilized by a combination of at least one liposoluble, free radical-scavenging antioxidant, preferably di-tert.-butyl methyl phenol, di-tert.-butyl metoxy phenol, tocopherol or ubiquinone and a basic ... 06/07/07 - 20070128264 - Method of cancer screening and method of cancer treatment A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive administering an needle biopsy; if the result is positive administering a PET scan; if the result is positive administering a blood ... 06/07/07 - 20070128263 - Transdermal therapeutic system The present invention relates to Transdermal Therapeutic Systems having a silicone adhesive layer, to Transdermal Therapeutic Systems providing specific plasma concentrations, to their manufacture and use. ... 06/07/07 - 20070128262 - Package containing adhesive patch and method of inhibiting drug migration [where R represents 2-isopropoxyethoxymethyl, carbamoylmethyl or 2-methoxyethyl.] ... 05/24/07 - 20070116752 - Transdermal drug delivery device comprising extensor-relaxor means A transdermal drug delivery device comprises a reservoir layer, which consists of one or more chambers for containing a drug. A lower surface of the reservoir layer is bounded by a resilient membrane, which is perforated by pores through which the drug may be delivered from the chambers. Connected to ... 05/10/07 - 20070104773 - Skin application medicament, method of applying the same to skin, and method of manufacturing the same The skin application medicament is used for treating or mitigating various symptoms on the skin, such as pimples, acne, comedo, wrinkles, rough skin, blotches, freckles, or the like. Generally, there is hitherto employed an application sheet comprising a predetermined amount of medicinal substances with other substances applied on unwoven fabric ... 05/10/07 - 20070104772 - Amorolfine patch for the treatment of onychomycosis A transungual patch/device useful for the treatment of onychomycosis includes: (i) a backing medium; and (ii) an adhesive matrix layer deposited thereon which contains (a) a thus effective amount of amorolfine active agent or derivative thereof essentially uniformly distributed therethrough, dissolved or dispersed in the adhesive, and (b) at least ... 05/10/07 - 20070104771 - Transdermal galantamine delivery system A transdermal galantamine delivery system to an individual. The system has a high galantamine loading with suitable permeation enhancers to effect therapeutic flux rate. Acrylate polymeric reservoir with the high galantamine and permeation enhancers dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties for multiple-day delivery. ... 05/03/07 - 20070098775 - Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels A pharmaceutical composition in the form of a solution, cream, lotion, spray, ointment, gel, aerosol, tablet, suppository or patch device for transdermal or transmucosal administration of alprazolam to a subject, which includes as a permeation enhancing mixture a fatty component in an amount of 0.1% to 20% by weight which ... 05/03/07 - 20070098774 - Method of delivering a medication A needleless microprotrusion method for infusion of a medicament into a patient includes disposing a substrate plurality of microprotrusions onto a patients' palm. A chemodenervating agent is disposed for delivery by the microprotrusions and the substrate supports and conforms the microprotrusions to the patients' palm in order to enable uniform ... 05/03/07 - 20070098773 - Needleless microprotrusion elastoplast system A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed for delivery by the microprotrusions and a substrate is provided for supporting the microprotrusions and conforming ... 05/03/07 - 20070098772 - Transdermal norelgestromin delivery system A system for transdermal delivery of norelgestromin (NGMN) to an individual. The system has a high NGMN loading with suitable permeation enhancers to effect therapeutic flux rate. Polyacrylate drug reservoir with the NGMN and high loading of one or more of permeation enhancers and NGMN dissolved therein provides desirable adhesive ... 05/03/07 - 20070098771 - High enhancer-loading polyacrylate formulation for transdermal applications A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and ... 05/03/07 - 20070098770 - Cosmetic path using method thereof, and cosmetic path package The present invention provides a cosmetic patch which can contain therein either one of a water soluble vitamin and a fat soluble vitamin, particularly when the vitamin is vitamin C, can contain and retain vitamin C stably while avoiding its deterioration due to oxidation or hydrolysis and not causing deterioration ... 04/19/07 - 20070087044 - Transdermal method and patch for emesis i. an antiemetically effective amount of a 5-HT3 receptor antagonist; ii. a permeation enhancing amount of permeation enhancer comprising 0.5% to 15% by weight of the skin-contacting layer; and iii. an adhesive. ... 04/19/07 - 20070087043 - Nicotine transdermal preparation and production method thereof The present invention provides a production method of a nicotine transdermal preparation, which is capable of producing a nicotine transdermal preparation conveniently and economically, while maintaining highly precise content uniformity, which is capable of producing a preparation simultaneously achieving fixedness and a soft feeling during adhesion, associated with reduced skin ... 04/12/07 - 20070082041 - Topical delivery of codrugs The present invention provides pharmaceutical compositions for topical delivery comprising a suitable carrier and a codrug capable of penetrating, or being transported across, the dermis. The codrug according to the invention comprises a first constituent moiety linked to a second constituent moiety, wherein the second constituent moiety is the same ... 04/12/07 - 20070082040 - Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of a peptide or polypeptide that generates hydrophilic micro-channels, and a patch comprising dried therapeutically peptide or polypeptide. Particularly, the system of ... 04/12/07 - 20070082039 - Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids, the use of the same as percutaneous permeation enhancers, and topical gels for the transdermal delivery of steroids The present invention provides a novel approach for the preparation of fatty alcohol esters of α-hydroxy carboxylic acids. The present invention also provides a novel topical gel for the transdermal delivery of steroids using the fatty alcohol esters as permeation enhancers. ... 04/12/07 - 20070082038 - Transdermal nicotine salt delivery system A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties. ... 04/12/07 - 20070082037 - Transdermal preparations and method for relieving side effects in pergolide therapy It is intended to provide pergolide-containing transdermal preparations having reducreduced side effects and exerting sufficient therapeutic effects. Namely, a pergolide-containing transdermal preparation which is capable of achieving a plasma AUC ratio of pergolide or the like to at least one pergolide metabolite of 1:0.5 to 1:5; and/or transdermal preparation containing ... 04/05/07 - 20070077288 - Transdermal delivery of non-steroidal anti-inflammatory drugs The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of a non-steroidal anti-inflammatory drug; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid. The invention also provides a method for administering at least ... 04/05/07 - 20070077287 - Transdermal art patch A transdermal patch having a pre-selected amount of a predetermined absorbable medicine thereon for attaching to an individual's skin. The transdermal patch includes a backing member having a predetermined size and a predetermined shape. The backing member has a first surface and a radially opposed second surface. A medicinal adhesive ... 04/05/07 - 20070077286 - Drug-containing nanoparticle, process for producing the same and parenterally administered preparation from the nanoparticle To provide an external preparation or injectable preparation that exerts the effect of enabling transdermal or transmucosal in viva absorption of fat-soluble drugs and water-soluble drugs not having been satisfactorily attained hitherto and that contains a highly absorbable fat-soluble/water-soluble drug, the injectable preparation especially aiming at sustained-release and target effects. ... 04/05/07 - 20070077285 - Adhesive skin patch The present invention provides an adhesive skin patch that permits excellent and prolonged percutaneous absorption of tulobuterol and that can be stably applied to the skin for a long period of time with less skin irritation. The adhesive skin patch comprises a base material and a medicated layer provided on ... 04/05/07 - 20070077284 - Transdermal formulation comprising an opioid analgesic and an aloe composition The invention concerns a formulation comprising an apioid analgesic from the phenanthrene group or a pharmaceutically acceptable salt thereof as active ingredient and an aloe composition as transdermal penetration agent. ... 03/29/07 - 20070071803 - Dermal penetration enhancers and drug delivery systems involving same The invention relates to a method for treatment or prophylaxis of a disease or condition in an animal comprising administering to a mucosal membrane of said animal in need of such treatment a therapeutically effective amount of a drug delivery system comprising at least one physiologically active agent or prodrug ... 03/29/07 - 20070071802 - Topical anesthetic for dental procedures A topical anesthetic for dental procedures is provided containing about 3 wt % to 10 wt % tetracaine in a vehicle suitable for administration to the oral mucosa. The vehicle for transporting the tetracaine includes a water soluble mucoadhesive or a combination of mucoadhesives such as a high molecular weight ... 03/29/07 - 20070071801 - Patch for treating symptoms of a skin abscess A patch, or bandage for treating skin infections has a backing with pressure-sensitive adhesive for securing on a user's skin in the area of the boil. A liquid absorbent member is positioned in the center of the patch, while a carrier with a medicinal formulation, comprising a menthol solution, surrounds ... 03/22/07 - 20070065496 - Dermal therapeutic system comprising 2-(3-benzophenyl)propionic acid The invention relates to a dermal therapeutic system having a cover layer, an adhesive matrix having a content of, as active ingredient, 2-(3-benzophenyl)propionic acid or [o-(2,6-dichloroanilino)phenyl]acetic acid or a derivative thereof customary in pharmacy, and a removable protective layer, characterised in that the adhesive matrix is an acrylate copolymer adhesive ... 03/22/07 - 20070065495 - Transdermal hormone delivery system: compositions and methods A transdermal hormone delivery system (THDS) is disclosed. The THDS is useful for control of fertility and as therapy for a variety of diseases and conditions treatable by robust delivery of progestin and estrogen hormones, particularly the progestin, levonorgestrel. The THDS comprises a backing layer, an adjoining adhesive polymer matrix ... 03/22/07 - 20070065494 - Formulations and methods for enhancing the transdermal penetration of a drug Methods and formulations of enhancing the permeability the skin of a subject to a drug are disclosed. The method may include administering a combination of lauryl alcohol and isopropyl myristate as a penetration enhancer to the area of skin to provide synergistically enhanced penetration of the drug. ... 03/22/07 - 20070065493 - External patch containing estrogen and/or progestogen An external patch capable of stable prolonged release and transdermal absorption of active ingredient hormones (estrogens and/or progestogens) contained in a pressure sensitive adhesive layer, which external patch ensures low irritation on the skin. In particular, an external patch comprising a support and, superimposed thereon, a pressure sensitive adhesive layer, ... 03/15/07 - 20070059351 - Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods The present invention is drawn to a transdermal patch for the delivery of a nitric oxide-donor and a second active agent. The patch can comprise a backing layer and an active agent-containing composition which is supported at least in part by the backing layer. The active agent-containing composition can include ... 03/08/07 - 20070053969 - Device for treating and promoting healing of damaged body tissue A device for treating and promoting healing of damaged body tissue. The device comprises an encapsulating device disposed adjacent the damaged tissue for controlling the environmental conditions surrounding the tissue. A transfer device is disposed on the encapsulating device to allow at least one of a predetermined medium to communicate ... 03/08/07 - 20070053968 - Transdermal drug delivery devices containing o-desmethyl venlafaxine (odv) or its salts The present invention provides transdermal drug delivery devices (i.e., patches) comprising O-desmethylvenlafaxine (ODV), a selective serotonin and norepinephrine re-uptake inhibitor, or a pharmaceutically acceptable salt thereof, which, among other, offer the advantage of eliminating or reducing the adverse side effects associated with the oral administration of ODV. Also provided are ... 03/08/07 - 20070053967 - Percutaneous absorption-type pharmaceutical preparations A percutaneous absorption-type pharmaceutical preparation containing a sublimation drug is provided, where from a plaster layer, a drug is released as volatile substance with a lapse of time, but the released drug has no adverse effect on the handling of the preparation, and the quality of the preparation is maintained ... 03/08/07 - 20070053966 - Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue A system and method for treating damaged musculoskeletal tissue includes an orthopedic support structure and a nitroglycerin-containing composition. The orthopedic support structure provides mechanical support to the damaged tissue and maintains the nitroglycerin-containing composition in contact with the skin of a subject wearing using the system. The nitroglycerin-containing composition can ... 03/08/07 - 20070053965 - Kit comprising a plaster, optionally containing an active substance, and an agent that at least partially reduces skin irritation A kit comprising a plaster, which contains a pharmaceutical active ingredient and is designed to administer the active ingredient transdermally to a human or animal to which the plaster is applied, and an agent that is separate from the plaster and at least reduces skin irritation from the plaster. ... 03/01/07 - 20070048362 - General purpose electrolyte solution composition for iontophoresis A single electrolyte solution composition may be used in an anode side and in a cathode side of an iontophoresis device. The electrolyte solution may include a compound having an oxidation-reduction potential lower than that of water, the compound including, in combination, both a component that is likely to be ... 02/22/07 - 20070042028 - Plaster causing reduced skin irritation A plaster containing an active ingredient for the transdermal administration of a pharmaceutical active ingredient, having a removable protective film and an adhesive layer. The plaster includes at least one compound that is contained in the adhesive layer or lies adjacent the adhesive layer between the adhesive layer and the ... 02/08/07 - 20070031479 - Bioadhesive gel based on hydroxyethycellulose Disclosed are compositions in the form of a bioadhesive gel that adheres to the mucous membranes, in particular the vaginal mucosa, for the application of active ingredients and/or principles, comprising hydroxyethylcellulose as the only gelling agent. ... 02/01/07 - 20070026056 - Antiviral patch An adhesive patch is provided wherein the patch includes a porous backing having a front side and a back side. The patch also includes a therapeutic formulation located on the front side of the backing. The backing includes a flexible sheet of water insoluble porous material. The therapeutic formulation includes ... 02/01/07 - 20070026055 - Production method of nicotine transdermal preparation The present invention provides a production method of a nicotine transdermal preparation, which includes a step of forming, on a support, an adhesive layer containing an adhesive and a liquid ingredient compatible with the adhesive, and a step of impregnating the adhesive layer with nicotine by continuously applying nicotine to ... 01/18/07 - 20070014839 - Decomposer film for transdermal patches The decomposer film product has a polymeric decomposer layer, a cover layer for protecting the decomposer film from the surroundings and a releasable support liner, which is removed prior to use. The polymeric decomposer film contains a water-soluble or water-insoluble polymeric adhesive material and a decomposition accelerator, which acts to ... 01/11/07 - 20070009588 - Adhesive patch An adhesive patch for percutaneous fentanyl administration which is easily produced, has long-term continuity, and is excellent in adhesion and conformability to the skin. The adhesive patch comprises a backing layer and a pressure-sensitive adhesive layer formed on one side thereof, wherein the pressure-sensitive adhesive layer comprises fentanyl as an ... 12/28/06 - 20060292210 - Percutaneous absorption-type pharmaceutical preparation A stable percutaneous absorption-type pharmaceutical preparation for percutaneous administration of selegiline or selegiline hydrochloride, which does not suffer a decrease in the cohesive force of the adhesive layer therein even in the presence of sweat components due to perspiration during wear and which is free from cohesive failure and resultant ... 12/21/06 - 20060286160 - Nicotine transdermal delivery system The present invention provides a nicotine transdermal delivery system including an adhesive layer containing a free base nicotine and a liquid ingredient compatible with the adhesive, wherein the adhesive layer is crosslinked, and the liquid ingredient is contained in a proportion of 20-75 parts by weight, per 100 parts by ... 12/21/06 - 20060286159 - Treatment of persistent active tendinopathy using transdermal glyceryl trinitrate providing durability of effect The present invention provides methods for treating tendinopathy providing a durability of effect by administering nitroglycerin. Such methods include methods for relieving pain associated with such tendinopathies. The use of a transdermal patch configured to deliver glyceryl trinitrate at a rate of 5 mcg/hr to about 85 mcg/hr ... 12/21/06 - 20060286158 - Treatment of overuse tendinopathy using transdermal nitric oxide-generating agents The present invention provides methods for treating tendinopathy in the absence of inflammation by the transdermal administration of nitroglycerin. Such methods include methods for relieving pain associated with such tendinopathies, and the use of a transdermal patch configured to deliver glyceryl trinitrate at a rate of 5 mcg/hr to about ... 12/07/06 - 20060275354 - Percutaneous absorption-type pharmaceutical preparation A stable percutaneous absorption-type pharmaceutical preparation for percutaneous administration of drugs except for selegiline and selegiline hydrochloride, which does not suffer a decrease in the cohesive force of the adhesive layer therein even in the presence of sweat components due to perspiration during wear and which is free from cohesive ... 11/16/06 - 20060257463 - Transmucosal delivery of cannabinoids A method of transmucosally delivering a cannabinoid to a subject in need of such treatment comprising the steps of: administering to the subject a transmucosal preparation containing the cannabinoid wherein said transmucosal preparation is made by incorporating an effective amount of the cannabinoid via hot-melt extrusion technology, hot-melt molding, admixing ... 11/09/06 - 20060251707 - Uv stable transdermal therapeutic plaster The invention relates to a UV stable transdermal therapeutic system (TTS) consisting of a back layer, at least one matrix containing an active substance and, optionally, a withdrawal film and an UV-radiation absorber. An adhesive layer containing said UV-radiation absorber is arranged between the back layer and the matrix containing ... 11/02/06 - 20060246122 - Solid transdermal therapeutic system with uv absorber The UV-stable solid transdermal therapeutic system (TTS) with UV absorber for photosensitive active pharmaceutical ingredients has a backing layer (1), at least one active ingredient-containing matrix (2), and a detachable protective film (3). Optionally an adhesive layer (4) and a separating layer (5) are introduced between the backing layer (1) ... 10/26/06 - 20060240087 - Composition and methods for drug delivery A dermal composition for administration of a drug comprising a blend of two or more acrylic-based polymers having differing functionalities so as to modulate the drug solubility in the polymer matrix and the delivery rate of the drug, and methods therefor. ... 10/26/06 - 20060240086 - Adhesive patch An adhesive patch which includes a pressure-sensitive adhesive layer comprising a composition which comprises: bisoprolol and/or a pharmaceutically acceptable salt thereof; and an acrylic polymer obtained by copolymerizing a (meth)acrylic ester with a carboxylated (meth)acrylic acid. The adhesive patch is stable and excellent in penetration through the skin. ... 10/26/06 - 20060240085 - Treatment of dependence withdrawal Dosage regimens of buprenorphine to treat withdrawal or abstinence syndrome in a drug dependent or opioid tolerant patient who is pregnant are described. The method includes treating withdrawal or abstinence syndrome of the patient by transdermal administration of an amount of buprenorphine effective to reduce withdrawal symptoms. For example, a ... 10/19/06 - 20060233871 - Transdermal delivery system for dried particulate or lyophilized medications The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of an agent that generates hydrophilic micro-channels, and a patch comprising a therapeutically active agent. The present invention is useful for transdermal ... 10/05/06 - 20060222693 - Transdermal patch bearing a decorative image A transdermal patch is disclosed for administering a drug to a human user. The transdermal patch includes a pigment layer having an image formed therein, a layer including the drug, and an adhesive layer for adhering the transdermal patch to the skin. ... 10/05/06 - 20060222692 - Method and compositions for transdermal administration of antimicrobial medications The present invention relates to methods and compositions for improved efficacy and delivery of time-dependent antimicrobial drug compositions to a patient. Transdermal dosage forms and methods for steady-state delivery of drug to produce and maintain a serum concentration of drug above the minimum inhibitory concentration or minimum microbicidal concentration are ... 09/28/06 - 20060216340 - Method of providing sustained analgesia with buprenorphine A method of effectively treating pain in humans is achieved by administering buprenorphine in accordance with first order kinetics over an initial three-day dosing interval, such that a maximum plasma concentration from about 20 pg/ml to about 1052 pg/ml is attained, and thereafter maintaining the administration of buprenorphine for at ... 09/28/06 - 20060216339 - Neuronal pain pathway The present invention relates to the discovery of a novel molecular pathway involved in long-term hyperexcitability of sensory neurons, which, in higher animals, is associated with persistent pain. It is based on the discovery that, following injury to an axon of a neuron, an increase in nitric oxide synthase activity ... 09/28/06 - 20060216338 - Composition and method of treatment for heel pain A topical medicament and associated methodology for use thereof, through the use of which tissue disorders involving collagen degeneration associated with repetitive microtears of the plantar fascia may be effectively, cost effectively, and painlessly treated. One or more calcium channel blocker agents serve as the primary active ingredient of the ... 09/28/06 - 20060216337 - Needeleless medication delivery system A Needleless injector patch for the intramuscular, subcutaneous, or intra-dermal delivery of a fluid medicament to a patient includes a plurality of cylindrical members “Micro-Injectors” which have a closed end and an sealed orifice end, the Micro-Jects contain a pyrotechnic charge, a piston and a quantity of medication. An onboard ... 09/21/06 - 20060210617 - Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl Silicone adhesive formulations are provided, in which fentanyl particles are suspended one or more a solvated silicone adhesives. The formulations can be used for manufacturing improved, matrix-type transdermal devices for administering fentanyl. ... 09/21/06 - 20060210616 - Therapeutic patch for ophthalmologic and cosmetic use This invention is directed to a therapeutic patch for ophthalmologic and cosmetic use that provides therapy to the region where the patch is provided; the therapeutic patch provides a therapeutic delivery surface for placement against, for example, the eyelid and peri-orbital structures of a patient, and a non-contacting surface that ... 09/21/06 - 20060210615 - Dermal or transdermal therapeutic system comprising an ormocer with barrier effect on a cover foil The invention relates to a dermal or transdermal therapeutic system comprising a cover foil with barrier effect against gas, odour and volatile light substances. Said invention is characterised in that the cover foil is provided with at least one substrate and with at least one layer consisting of an inorganic-organic ... 09/14/06 - 20060204564 - Compositions and kits for the removal of irritating compounds from bodily surfaces The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble. ... 09/14/06 - 20060204563 - Compositions and kits for the removal of irritating compounds from bodily surfaces The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleaning composition, e.g., a composition in which capsaicin is soluble. ... 09/07/06 - 20060198881 - Tamper resistant transdermal dosage form The invention comprises a transdermal dosage form comprising an active agent component comprising an active agent and an adverse agent component comprising an adverse agent, wherein the active agent component defines at least one channel extending substantially there through. ... 08/24/06 - 20060188558 - Transdermal systems having control delivery system Transdermal delivery systems are disclosed including a backing layer, a polymer membrane within the backing layer, an adhesive layer for attaching the delivery system to the patient's skin or mucosa, and a releasable layer covering the adhesive layer prior to use, the polymer membrane impregnated with sufficient fluid medium to ... 08/24/06 - 20060188557 - Prepartaion for external percutaneous administration containing non-steroidal anti-inflammatory drug and interleukin-1 alpha production inhibitor A transdermal formulation for external application comprising a non-steroidal anti-inflammatory analgesic, an alkyl ester of gallic acid, and a phenolic radical scavenger having a branched-chain lower alkyl group. An interleukin-1α production inhibitor consisting of a phenolic radical scavenger having a branched-chain lower alkyl group, and/or an alkyl ester of gallic ... 08/17/06 - 20060182791 - Transdermaltherapeutic system containing a pramipexol active agent The invention relates to a transdermal therapeutic system (TTS) releasing an active pramipexol agent during a time ranging from 4 to 7 hours. ... 08/10/06 - 20060177494 - Coated microprojections having reduced variability and method for producing same The present invention provides methods and devices for reducing the coating variability of a transdermal microprojection delivery device. The device has one or more stratum corneum-piercing microprojections, wherein each microprojection has a maximum width located in the range of approximately 25% to 75% of the length of the microprojection and ... 08/10/06 - 20060177493 - Transdermal granisetron Adhesive patches for the transdermal administration of granisetron, comprise an acrylic adhesive containing non-acidic nucleophilic moieties which substantially increase flux of granisetron across the skin. ... 08/03/06 - 20060172002 - Patch containing nonsteroidal antinflammatory and analgesic agent An adhesive patch containing a non-steroidal anti-inflammatory agent, comprising a support and an adhesive layer laminated on this support, wherein the adhesive layer contains a non-steroidal anti-inflammatory agent having a carboxyl group or its salt, and polyethylene glycol having an average molecular weight of 1000 or more. ... 07/27/06 - 20060165765 - Topical glycopyrrolate product This invention relates to a convenient and safe product and method of applying glycopyrrolate topically in order to reduce excessive sweating in localized areas for those who suffer from this condition. This invention also relates to combining oral and topical delivery of glycopyrrolate to reduce excessive sweating and minimize side ... 07/13/06 - 20060153905 - Transdermal pharmaceutical formulation for minimizing skin residues This invention relates to novel transdermal or transmucosal pharmaceutical formulation which reduces the occurrences of contamination of other individuals and the transference to clothing of the user. The novel formulation includes at least one pharmacologically active ingredient, and a solvent system having a monoalkylether of diethylene glycol and a glycol ... 07/06/06 - 20060147510 - Method for treating non-neuropathic pain A method including topically administering an effective amount of local anesthetic to a patient is disclosed. The method is effective for inducing analgesia for treating non-neuropathic pain. Non-neuropathic pain suitable for treatment according to the invention includes pain associated with sports injuries; sprains; strains; soft-tissue injury; repetitive motion injury; carpal ... 07/06/06 - 20060147509 - Composition for vaccination The present invention provides novel compositions for transdermal delivery of at least one immunogen to an individual, which compositions comprise (a) said at least one immunogen (b) an occlusion vehicle and (c) an immunogen delivery system in the form of a PosIntro or a cationic ISCOM or comprising at least ... 06/22/06 - 20060134188 - Transdermal pharmaceutical preparation with a progesterone a-specific ligand (prasl) as active ingredient or a pharmaceutically suitable derivative thereof. ... 06/22/06 - 20060134187 - Method for treating inflammation associated with acne The present invention is directed to a method of treating the inflammation associated with acne, comprising applying a patch to an affected area of the skin, wherein said patch includes an efficacious amount of a cortisone. The patch of the present invention may be self adhesive or treated with a ... 06/22/06 - 20060134186 - Oxygenating agents for enhancing host responses to microbial infections Oxygenating agents are used in the present invention for the novel purpose of treating microbial infections. The invention takes advantage of the fact that the increase in tissue pO2 produced thereby can enhance the efficacy of the body's own antimicrobial defenses (including tissue repair), while also improving the efficacy of ... 06/15/06 - 20060127465 - Pad base for transdermal administration and needle The object of the present invention is to provide a pad base for endermism which hardly causes bad influence on organism even if a needle fractures in the skin and remains in the MicroPatch method. It is the pad base for endermism in which a minute needle 1 is installed ... 06/15/06 - 20060127464 - Female hormone-containing patch Provided herein is a female hormone-containing patch wherein an active ingredient is highly soluble in a pressure-sensitive adhesive layer and the active ingredient is not adsorbed to a backing, and the patch per se can follow the irregularities on the skin surface or body movements. The patch is an external ... 06/08/06 - 20060121104 - Transdermal delivery system for dried particulate or lyophilized medications The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of an agent that generates hydrophilic micro-channels, and a patch comprising a therapeutically active agent. The present invention is useful for transdermal ... 06/08/06 - 20060121103 - Transdermal delivery system A transdermal delivery system (TDS) for use in treatment of living bodies may be applied as an open (liquid, gel) or closed (patch) article. The TDS is composed of a particular active agent which dictates an associated selection of certain solvents, solvent modifiers, solute modifiers and skin stabilizers with which ... 06/08/06 - 20060121102 - Transdermal systems for the delivery of estrogens and progestins Transdermal systems are provided for administering an estrogen and/or a progestin to a mammalian female. The systems are monolithic, having a drug reservoir that serves as the means for ensuring adhesion to the skin during drug administration. The drug reservoir includes the active agent(s), a low molecular weight organic acid ... 05/18/06 - 20060105030 - Transdermal therapeutic system The invention concerns a transdermal therapeutic system containing ergoline derivatives, preferably lisuride, with a stabilized ergoline compound. Stabilization of the oxidation sensitive ergoline combination is done through a combination of at least one fat-soluble, radical-trapping antioxidant, preferably Di-tert.-butylmethylphenols, Di-tert.-butylmetoxyphenols, tocopherols or ubichinones and a basic polymer. Use of a transdermal ... 05/11/06 - 20060099242 - Matrix for transdermal drug delivery A transdermal drug delivery device involving a macromonomer-containing acrylate or methacrylate copolymer, a softener, and a drug. Also a pressure sensitive skin adhesive involving a macromonomer containing acrylate or methacrylate copolymer and a softener. ... 05/04/06 - 20060093659 - Hydroxide-releasing agents as skin permeation enhancers A method is provided for increasing the permeability of skin or mucosal tissue to topically or transdermally administered pharmacologically or cosmeceutically active agents. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the active agent through a body surface ... 04/27/06 - 20060088581 - Device for delivery of therapeutic agent The invention provides a system for administering to or through the skin of the individual selected medicaments. The system includes an orthosis and a pad. The pad includes at least one delivery station suitable for containing the medicament. The pad may be positioned in a variety of configurations on the ... 04/27/06 - 20060088580 - Hormone-containing transdermal therapeutic system with an active substance reservoir based on vinylacetate-vinylpyrrolidone copolymer with improved cohesion A transdermal therapeutic system in patch form for the controlled delivery of active substances to the human or animal skin comprises a backing layer, an active substance-containing reservoir attached thereto and a detachable protective layer, is characterized in that the active substance-containing reservoir contains as main components thereof at least ... 04/13/06 - 20060078604 - Transdermal drug delivery device including an occlusive backing A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the ... 04/13/06 - 20060078603 - Transdermal delivery of drugs based on crystal size A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. According to ... 04/13/06 - 20060078602 - Device for transdermal administration of drugs including acrylic polymers A transdermal delivery system is provided where the drug delivery rates, onset and profiles of at least one active agent are controlled by selectively manipulating the monomeric make up of an acrylic-based polymer in the transdermal drug delivery system. The drug carrier composition may be comprised of (a) one or ... 04/13/06 - 20060078601 - Compositions and methods for delivering estradiol in transdermal drug delivery systems A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. ... 04/13/06 - 20060078600 - Transdermal therapeutic system suitable for heat application for promoting the permeation of active substances, and the use thereof The invention relates to a transdermal therapeutic system (TTS) comprising at least one pharmacological active substance, which is suitable for heating up to a temperature above skin temperature, thereby promoting the permeation rate of the active substance. The transdermal therapeutic system comprises at least one layer containing the active substance ... 03/30/06 - 20060067996 - Preventing/treating signs of skin stress/aging by bioenergetically modifying acupuncture points of the face or neck A regime or regimen for preventing and/or treating the signs of aging and/or stress of the skin, especially for (i) smoothing skin wrinkles and/or relaxing marks on the forehead and/or (ii) tonifying the cheeks, entails topically applying, advantageously via transdermal delivery, onto at least one acupuncture point of the face ... 03/30/06 - 20060067995 - Topical and/or transdermal bioactive compound delivery system Topical and/or transdermal bioactive compound delivery system The present invention provides a topical and/or transdermal bioactive compound delivery system comprising a non-aqueous matrix, the matrix comprising a water-sensitive bioactive compound. In particular, the matrix comprises a three-dimensional polymeric network comprising at least a co-polymer, at least a cross-linking agent, and ... 03/30/06 - 20060067994 - System for providing therapy to a body Some embodiments of the present invention relate to a system, kit and method for providing therapy to a portion of a body. The system includes a holder and a therapeutic patch that is held by the holder. The therapeutic patch applies therapy to the portion of the body when the ... 03/30/06 - 20060067993 - Topical anesthetic patch A pre-vaccination or pre-procedural topical anesthetic patch which functions not unlike a nicotine patch and which is essentially a round Band-Aid® containing a topical anesthetic. The Band-Aid® anesthetic carrying device may be of any shape or size. It is applied to a persons skin at a site where a needle ... 03/23/06 - 20060062838 - Biosynchronous transdermal drug delivery Systems and methods for treating diseases, addictions and disorders in humans and animals involving synchronizing and tailoring the administration of drug compounds with the body's natural circadian rhythms, in order to counteract symptoms when they are likely to be at their worst. Automated and pre programmable transdermal drug administration system ... 03/23/06 - 20060062837 - Dual activating tdd Preferred embodiment FIG. 1, comprises a novel transdermal delivery device for ensuring longer shelf life of unstable drugs comprising a patch for disbursement of therapeutic drugs to the skin of a user; said patch comprising an inbuilt injection port in which the user injects the diluent and/or active ingredient(s) into ... 03/23/06 - 20060062836 - Methods of device-assisted drug delivery This invention describes the simultaneous or sequential administration of therapeutic or diagnostic agents using different devices in combination with a chemical formulation that incorporates or uses vasomodulatory chemical agents as part of the drug delivery vehicle. Methods include the addition of various vasodilatory and vasoconstrictive agents to enhance the systemic ... 03/09/06 - 20060051404 - Microstructure roller system A microstructure for transferring a substance through the surface of the skin, comprising a substrate having a first and a second side and at least one microstructure projecting from the second side of the substrate. The micrstructure has at least one hollow. The hollow is isolated from the fluid connection ... 02/23/06 - 20060039961 - Percutaneous absorption accelerator The present invention has as an object to provide a composition for external use on skin whose percutaneous absorption of an active component is increased, whereby a large amount of the active component can be delivered into the skin. By employing diglycerol and a low molecular weight betaine together, a ... 02/23/06 - 20060039960 - Plaster containing fentanyl The invention relates to a transdermal, therapeutic system comprising a coating layer and an adhesive matrix having a fentanyl content. ... 02/16/06 - 20060034905 - Adhesive composition An adhesive composition is described which has improved initial tack, long-term adhesion, water uptake and translucency characteristics and may be prepared by melt extrusion. Uses of these compositions are also described, for example, their use as blister pads and wound dressings. ... 02/16/06 - 20060034904 - Transdermal delivery using emcapsulated agent activated by ultrasound and or heat A method for delivery of substance through at least one dermal layer, by providing a substance in microcapsules at a predetermined size, within a medium (150) for holding the microcapsules; placing the medium for holding the microcapsules on a surface of a patch (100) adjacent the skin (320) of a ... 02/09/06 - 20060029654 - Analgesic patch for sports injury rehabilitation medicine and method to alleviate pain The present invention relates to a method for topical treatment of pain resulting from a sports injury, including injuries to bones and soft tissue, such as ligaments, muscles or tendons. The method includes the steps of: applying to skin of a subject suffering from pain resulting from a sports injury ... 01/19/06 - 20060013867 - Medical devices and materials containing isobutylene copolymer The present invention relates to medical devices which contain isobutylene copolymers. The present invention also relates to biocompatible copolymer materials for therapeutic agent delivery comprising a therapeutic-agent-loaded isobutylene copolymer. According to an aspect of the present invention, a medical device is provided, which includes: (a) a substrate and (b) at ... 01/19/06 - 20060013866 - Transdermal drug delivery formulations with optimal amounts of vasodilators therein Topical drug delivery formulations with optical amounts of vasodilator. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and/or inhibition has been found to be dependent on ... 01/19/06 - 20060013865 - Transdermal patch for external use comprising fentanyl A transdermal patch for external use having a backing layer and a pressure-sensitive adhesive layer formed on one surface of the backing layer, which contains polyisobutylene, a mineral oil and fentanyl employed as the active ingredient in the pressure-sensitive adhesive layer and in which the contents of polyisobutylene and fentanyl ... 01/12/06 - 20060008516 - Gilsonite derived pharmaceutical delivery compositions and methods: cosmetic applications Pharmaceutical formulations comprising Gilsonite oil for topical or transdermal application are disclosed. Also provided are methods for transdermal administration of a bioactive agent with enhanced penetration which comprise topical administration of a composition comprising transdermally effective amount of Gilsonite oil. ... 12/29/05 - 20050287195 - Transdermal drug delivery systems In a method of manufacturing such a system, an active substance is dissolved in a ratio less than saturation level in a solvent which is also a skin penetration enhancer. The system is coated as a layer onto a siliconized release paper and laminated onto a backing strip. ... 12/22/05 - 20050281869 - Self-adhesive polymer matrix containing a seaweed extract A self-adhesive polymer matrix which comprises a polymer that forms a gel in water, water, a sea algae extract, and a monohydric or polyhydric alcohol. ... 12/22/05 - 20050281868 - Transdermal delivery system for statin combination therapy The present invention relates to transdermal drug delivery systems for the safer delivery of statin drugs to provide lessened danger or severity of side effects. ... 12/01/05 - 20050266063 - Adhesive patch The present invention relates an adhesive patch comprising a backing layer and an adhesive layer that contains a drug, wherein the adhesive layer contains a mixed adhesive base containing a hydrocarbon rubber and a silicon-containing polymer. The adhesive patch of the invention shows extremely superior skin absorbability of a drug ... 12/01/05 - 20050266062 - Percutaneous absorption preparation containing 3-methyl-1-phenyl-2-pyrazolin-5-one or a medically acceptable salt thereof in an appropriate base such as an aqueous base or a rubber base. This preparation (or adhesive preparation) is an excellent percutaneous absorption preparation (or percutaneous absorption adhesive preparation) which has good percutaneous absorbability of the active ingredient and causes little skin irritation. ... 11/24/05 - 20050260255 - Adhesive patch A patch comprising a backing layer and an adhesive layer disposed on the backing layer and compounded with a drug and an adhesive base agent, wherein the adhesive base agent comprises styrene-isoprene-styrene block copolymer, 2-ethylhexyl acrylate—vinyl acetate copolymer and a basic nitrogen-including polymer including a basic nitrogen and having no ... 11/24/05 - 20050260254 - Hot melt tts for administering rotigotine The invention relates to a transdermal therapeutic system (TTS) which contains a rotigotine-containing adhesive layer and is characterized by the fact that the adhesive layer contains a hot-meltable contact adhesive. The invention also relates to the use of rotigotine for producing the adhesive layer of a TTS in a hot ... 11/17/05 - 20050255151 - Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor ... 11/17/05 - 20050255150 - Wound treatment patch for alleviating pain Methods and topical patches for outpatient treatment of moderate to severe pain with an opioid, for example, the pain caused by surgically closed wounds. The methods and patches of the invention comprise: (1) a local-anesthetic component for local delivery of a local anesthetic; and (2) an opioid component for transdermal ... 11/10/05 - 20050249793 - Athletic patch The present invention relates to patches for the administration of an athletic supplement to subjects engaged in rigorous exercise or heavy outdoor work. The invention also relates to methods of administering nutrients to subjects using the patch of the invention. ... 11/10/05 - 20050249792 - Active ingredient release system comprising a plaster containing an active ingredient and at least one active ingredient release regulator An active ingredient release system for the systemic or topical release of an active ingredient into a human or animal organism, including: a) a plaster containing active ingredient, and b) at least one divisible active ingredient release regulator that is impermeable to the active ingredient, or at least one optionally ... 11/03/05 - 20050244486 - Topical methadone compositions and methods for using the same Methods and compositions are provided for administering methadone to a subject. Aspects of the invention include employing a topical methadone formulation, e.g., a patch or analogous topical administration formulation. The subject methods and compositions find use in a variety of applications, e.g., in the treatment of a variety of different ... 10/27/05 - 20050238704 - Transdermal drug delivery method and system The invention concerns a transdermal delivery system for controlled dispensing of an active substance to and through a porous surface. A certain amount of fluid comprising at least one active substance and at least one solvent is dispensed into an administration reservoir. In the administration reservoir the at least one ... 10/20/05 - 20050232983 - Transdermal patch A transdermal delivery system for pyrrole derivatives of formula 1, metabolites thereof, enantiomers thereof, racemates thereof, and salts including acid addition salts thereof, alone or in conjunction with one or more other therapeutic agents, using vehicles selected to enhance absorption and which enable the compounds to be administered into and ... 10/20/05 - 20050232982 - Phentanyl-containing adhesive patch for application to oral-cavity mucosa To provide a patch containing fentanyl for mucous membrane of the oral cavity (oral transmucosal fentanyl), which rapidly increases the serum concentration of the drug, is easy in handling and is superior in safety. A patch containing fentanyl for mucous membrane of the oral cavity, which can be prepared by ... 10/13/05 - 20050226922 - Apparatus and method for transdermal delivery of fentanyl-based agents An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In ... 10/13/05 - 20050226921 - Non-invasive analysis and controlled dosage transdermal active patch A programmable transdermal patch non-invasively delivers pharmaceuticals or other bio-active agents through the skin of a living body. The patch contains one or more agent storage pads and one or more active drivers that apply an electric current to the skin or produce ultrasound to drive the agent into the ... 10/13/05 - 20050226920 - Method of decreasing nicotine withdrawal symptoms during smoking cessation. Injecting a patient with a solution of anticolenergic medications can alleviate the symptoms of nicotine withdrawal. Used in conjunction with pre injection and post injection counseling, smoking cessation rates may be significantly improved. ... 10/13/05 - 20050226919 - Device for transdermal administration for the treatment of urinary tract disorders This invention provides a device containing a compound of formula (I), wherein R represents a saturated or unsaturated C2-7 aliphatic acyl group optionally substituted by one or more halogen atoms, a hydroxy group, a C1-6 alkoxy group, a carboxyl group, a C2-7 alkoxycarbonyl group, a 5 to 7-membered cycloalkyl group, ... 10/13/05 - 20050226918 - Delivery system for insulin and other therapeutic agents An automated, non-implanted, closed-loop system for measurement of a biological material in an individual, determination of appropriate steady-state and bolus drug delivery response to the measured level of the biological material, and storage and delivery of a hormone, drug, or other chemical or biochemical therapeutic agent that serves to regulate ... 10/06/05 - 20050220855 - Transdermal therapeutic system Use of a transdermal therapeutic system (TTS) comprising a pharmaceutical layer containing at least one matrix having an active ingredient and/or an active ingredient reservoir; a diffusion barrier that is permeable to said active ingredient and arranged on the skin side of the active ingredient reservoir; and an ergoline derivative ... 10/06/05 - 20050220854 - Apparatus and method for transdermal delivery of influenza vaccine An apparatus and method for transdermally delivering an immunologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers, the ... 10/06/05 - 20050220853 - Controlled delivery of therapeutic agents from medical articles The present invention provides novel adenosine receptor antagonists, more particularly, A1 adenosine receptor antagonists. Pharmaceutical compositions comprising an A1 adenosine receptor antagonist disclosed herein and a pharmaceutically acceptable carrier are further provided. Compositions also include diagnostic assay-type probes comprising a novel A1 adenosine receptor antagonist that is labeled or conjugated ... 10/06/05 - 20050220852 - Adhesive patch containing tulobuterol A patch containing turobuterol in the low concentration and having the stable release-controllability, prepared by laminating an adhesive layer consisting of a rubber, an adhesive resin and a plasticizer on a backing, wherein 1 to 4 w/w % of turobuterol in the lower concentration as an active ingredient and 0.1 ... 10/06/05 - 20050220851 - Matrix type patch containing bronchodilators The present invention relates to a matrix type patch for the transdermal delivery of a bronchodilator which is consisted of a backing layer, a pressure-sensitive adhesive layer comprising a drug, and a release liner, wherein the said pressure-sensitive adhesive layer comprises as the drug component at least one of brochodilators ... 09/29/05 - 20050214354 - Packaging system for transdermal drug delivery systems A device and method for stabilizing a drug, particularly a chiral drug or the active enantiomer(s) thereof, in a carrier composition of a transdermal delivery system prior to the systems use by providing a product packaging system to prevent or control degradation reactions that can result from certain packaging materials ... 09/29/05 - 20050214353 - Transdermal therapeutic system Use of a transdermal therapeutic system (TTS) comprising a pharmaceutical layer containing at least one matrix having an active ingredient and/or an active ingredient reservoir; a diffusion barrier that is permeable to said active ingredient and arranged on the skin side of the active ingredient reservoir; and an ergoline derivative ... 09/29/05 - 20050214352 - Patch and process for producing the same The present invention relates to a patch containing a substrate, a non-crosslinked adhesive layer (A) containing DMAE or a pharmacologically acceptable salt thereof laminated on one surface of the substrate and a crosslinked adhesive layer (B) laminated on the adhesive layer (A). According to the present invention, the percutaneous absorbability ... 09/22/05 - 20050208117 - Transdermal administration of fentanyl and analogs thereof A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed. ... 09/22/05 - 20050208116 - Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised A device for the transdermal delivery of a pharmacologically active substance has first and second superimposed mutually contacting adhesive layers (2, 3). The first layer (3) is in use brought into contact with the skin. The active substance is dissolved in both layers, the affinity of the first layer for ... 09/15/05 - 20050202073 - Transdermal systems containing multilayer adhesive matrices to modify drug delivery A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein the drug and having a first delivery profile of the drug; a second polymeric adhesive matrix, in contact ... 09/08/05 - 20050196434 - Pharmaceutical composition and method for the transdermal delivery of magnesium The present invention relates to a method and transdermal pharmaceutical composition for preventing magnesium deficiency or imbalances associated with magnesium deficiency including diabetes, hypertension, high cholesterol, cardiac arrhythmias, acute myocardial infarction, arteriosclerosis, atherosclerosis, preeclampsia, dysautonomia, mitral valve prolapse, asthma, constipation, irritable bowel syndrome, migraines, muscle spasms and cramping, premenstrual syndrome, ... 09/08/05 - 20050196433 - Pharmaceutical composition and method for the transdermal delivery of magnesium The present invention relates to a method and transdermal pharmaceutical composition for preventing magnesium deficiency or imbalances associated with magnesium deficiency including diabetes, hypertension, high cholesterol, cardiac arrhythmias, acute myocardial infarction, arteriosclerosis, atherosclerosis, preeclampsia, dysautonomia, mitral valve prolapse, asthma, constipation, irritable bowel syndrome, migraines, muscle spasms and cramping, premenstrual syndrome, ... 09/01/05 - 20050191340 - Opioid-receptor antagonists in transdermal systems having buprenorphine Transdermal systems with an active agent such as buprenorphine and an opioid receptor antagonist are provided. The opioid receptor antagonist may include a μ, κ or δ opioid receptor antagonist. Methods of treatment using such a system are also provided. ... 09/01/05 - 20050191339 - Skin friendly active ingredient plaster based on sbc, containing at least 34 wt.% of a pharmaceutical active ingredient and production thereof An active ingredient containing bandage for the controlled delivery of a pharmaceutically active ingredient to the skin. The bandage comprises a flexible cover layer and a water-insoluble, adhesive styrene block copolymer (SBC)-based matrix that comprises at least 34% by weight of the pharmaceutically active ingredient. ... 09/01/05 - 20050191338 - Transdermal drug delivery composition comprising a small molecule gel and process for the preparation thereof This invention relates to a transdermal drug delivery composition comprising a small molecule gel, which small molecule gel comprises a small molecule gelling agent and a solvent, in which solvent is dissolved or suspended (a) a drug that is suitable for transdermal delivery and (b) a skin permeation enhancer. The ... 08/25/05 - 20050186262 - Transdermal delivery device for dihydropyridine type calcium antagonists A transdermal delivery device for delivering dihydropyridine-type calcium antagonists through the skin for treatment of hypertension. The device may comprise a backing layer and an adhesive matrix reservoir. The adhesive matrix reservoir is affixed to a side of the backing layer and may comprise at least one fatty acid permeation ... 08/18/05 - 20050181033 - Method for delivering interferons to the intradermal compartment The present invention relates to methods and devices for intradermal delivery of substances, preferably therapeutic substances by targeting the substance to the intradermal compartment of a subject's skin. Substances delivered in accordance with the methods of the invention have an improved clinical utility and therapeutic efficacy relative to other drug ... 08/18/05 - 20050181032 - Metastable pharmaceutical compositions The present invention provides a pharmaceutical composition for transdermal delivery comprising; one or more physiologically active agents; and a volatile pharmaceutically acceptable solvent; and wherein the physiological active agent forms a metastable deposit upon evaporation of the volatile solvent. ... 08/11/05 - 20050175680 - Transdermal delivery rate control using amorphous pharmaceutical compositions and wherein the physiologically active agent and dermal penetration enhancer form an amorphous deposit upon evaporation of the volatile carrier, said amorphous deposit forming a reservoir within the stratum corneum; and (A) wherein the composition has a release rate profile of physiologically active agent so as to provide a ratio ... 08/11/05 - 20050175679 - Controlled release formulations The present invention relates to controlled release transmucosal formulations which mediate absorption and methods of use comprising a pharmaceutically active agent, preferably morphine, and a water soluble polymer, chitosan, and preferably one more antioxidants, one or more antimicrobial agents, and water. ... 08/04/05 - 20050169977 - Compositions and methods for controlling drug loss and delivery in transdermal drug delivery systems A transdermal delivery system is provided for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric and/or adhesive coating that is applied to either the transdermal system's backing or release liner. The transdermal delivery ... 08/04/05 - 20050169976 - Insulin administration apparatus The present device is used to percutaneously or transmucosally administer an insulin lispro represented by the structural formula indicated below, or a pharmaceutically acceptable salt thereof, using iontophoresis and electroporation. ... 07/28/05 - 20050163831 - Patch for transdermal administration A patch for transdermal administration having a sufficiently high transdermal permeation property of a COX-2 inhibitor to exert a superior antiinflammatory effect, the patch for transdermal administration comprising a backing and an adhesive layer which is placed on at least one side of the backing and comprises an adhesive base ... 07/28/05 - 20050163830 - Taste-masked film-type or wafer-type medicinal preparation The invention relates to thin film-shaped or wafer-shaped pharmaceutical preparations for oral administration of active substances. The preparations contain at least one matrix-forming polymer which has at least one active substance and at least one carbon dioxide-forming substance dissolved or dispersed therein. ... 07/21/05 - 20050158371 - Novel external agent The present invention relates to a transdermal administration preparation for external application such as ointment, cream and the like, which contains SMP-114 or leflunomide or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. The present invention further relates to a pharmaceutical composition for transdermal administration which contains, ... 07/14/05 - 20050152958 - Ketoprofen patch delivery system A controlled release ketoprofen patch for the topical application of ketoprofen is described, in addition to methods of treating inflammatory disorders and pain disorders by the administration of the controlled release ketoprofen patch. ... 06/30/05 - 20050142176 - Transdermal patch for long-term steady release A patch containing at least one drug component is disclosed. The patch includes: a protecting membrane; a drug reservior layer containing a first concentration of the drug; an adhesion layer containing a second concentration of the drug and being in contact with the skin; and a release liner; wherein the ... 06/30/05 - 20050142175 - Transdermal delivery of hormones without the need of penetration enhancers The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the ... 06/30/05 - 20050142174 - Adhesive and binding agent for dermal or transdermal treatment systems The invention relates to an adhesive and binding agent for dermal or transdermal treatment systems, said agent containing (a) a (meth)acrylate copolymer consisting of radically polymerised C<sb>1</sb>to C<sb>4</sb>alkyl esters of acrylic or methacrylic acid and (meth)acrylate monomers having a cationic ammonium group in the alkyl radical; (b) between 0.1 and ... 06/23/05 - 20050136103 - Compositions capable of facilitating penetration across a biological barrier This invention relates to novel pharmaceutical compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering these compositions to affected subjects. ... 06/23/05 - 20050136102 - Enhanced transport using membrane disruptive agents Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure ... 06/16/05 - 20050129749 - Multi-layer transdermal drug delivery device A drug delivery device initially having two adhesive layers containing at least one active agent in each layer are kept separate from each other prior to administration of the active agent. At the time of administration, the separated layers are combined to form a dual layer adhesive transdermal drug delivery ... 06/16/05 - 20050129748 - Percutaneous absorption type plaster A transdermal patch comprising a backing 2 and an adhesive layer 3 laminated on the backing 2, wherein the adhesive layer 3 comprises a rosin-based resin and petroleum resin as a tackifier, the total compounding amount of the rosin-based resin and the petroleum resin is in a range of 15% ... 06/02/05 - 20050118247 - Method of making ketoprofen patch delivery system A controlled release ketoprofen patch for the topical application of ketoprofen is described, in addition to methods of treating inflammatory disorders and pain disorders by the administration of the controlled release ketoprofen patch. ... 06/02/05 - 20050118246 - Dosage forms and layered deposition processes for fabricating dosage forms Disclosed are transdermal or transmucosal dosage forms which include a matrix and a drug where the total amount of drug present in the dosage form exceeds the solubility limit of the drug in the matrix. Also disclosed are transdermal or transmucosal dosage forms which include two or more drug-containing layers ... 06/02/05 - 20050118245 - Assembled unit consisting of individually separable, transdermal, therapeutic systems The invention relates to an assembled unit consisting of individually separable transdermal therapeutic systems. ... 06/02/05 - 20050118244 - Transmittal therapeutic systems containing steroid hormones and propylene glycol monocaprylate The invention relates to transdermal therapeutic systems containing at least one steroid hormone and propylene glycol monocaprylate as permeation enhancers. The invention also relates to methods for the production of said systems and to the use of the same in hormone substitution therapy and contraception. ... ### FreshPatents.com Support |