REGISTER now for FREE 
|
FREE patent keyword monitoring and additional FREE benefits. REGISTER now for FREE
|
|
|
Drug, Bio-affecting And Body Treating Compositions > Preparations Characterized By Special Physical Form Preparations Characterized By Special Physical FormPreparations Characterized By Special Physical Form patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.07/19/07 - 20070166336 - Stable and palatable oral liquid sumatriptan compositions The present invention is directed to improved oral liquid compositions that include sumatriptan, or a pharmaceutically acceptable salt or metabolite thereof, and a pharmaceutically acceptable carrier that includes a liquid portion of the composition. The compositions are substantially free of oxidation impurities. Typically, the compositions include a sweetening agent and ... 07/05/07 - 20070154498 - Intravenous essential fatty acid emulsion A method for preventing stenosis and thrombosis of an AV graft is disclosed. An essential fatty acid emulsion is administered to the patient through the AV graft, preferably during dialysis, whereby the anti-inflammatory properties of the essential fatty acid emulsion prevent complications typical of AV grafts. ... 07/05/07 - 20070154497 - Stable, palatable syrup containing ibuprofen and method of its preparation The invention concerns stable, palatable syrups for oral administration, containing S(+)-ibuprofen, hydroxypropyl beta-cyclodextrin, at least one sweetener and water, optionally essential oils. It also includes methods of preparation of the syrups of the invention, wherein crystalline S(+)-ibuprofen is dissolved in a hydroxypropyl beta-cyclodextrin aqueous solution and the final concentration of ... 06/28/07 - 20070148195 - Compositions and methods for transdermal oxybutynin therapy The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy. In one aspect, these compositions and methods provide a lower plasma concentration of oxybutynin metabolites, such as N-desethyloxybutynin, which is presumed to be contributing at ... 06/28/07 - 20070148194 - Novel nanoemulsion formulations An oil-in-water nanoemulsion delivery system that includes at least one oil having a concentration of greater than or equal to 2% (w/w) of at least one polyunsaturated fatty acid, preferably of the omega-3 or omega-6 family, is disclosed. The delivery system further includes at least one emulsifier and also an ... 06/28/07 - 20070148193 - Lutein concentrate The invention relates to a lutein solubilized product comprised of one part, which consists of a lutein-containing composition, and of approximately 7 to approximately 9 parts polysorbate, and to a method for the production thereof, during which a lutein-containing composition is mixed with approximately seven to nine times the amount ... 06/28/07 - 20070148192 - Stable ophthalmic composition The present invention provides a clear stable ophthalmic composition comprising (a) an anti-infective agent; (b) a steroidal anti-inflammatory agent; (c) a complexing agent capable of forming an inclusion complex and (d) other pharmaceutically acceptable excipients in a liquid vehicle such that the composition is free of any other complexation enhancing ... 06/21/07 - 20070141093 - Lipophilic di(anticancer drug) compounds, compositions, and related methods Lipophilic di(anticancer drug) compounds, compositions that include the compounds, and methods for treating a cell proliferative disease using the compounds. ... 06/21/07 - 20070141092 - Biguanide composition and method of treatment and prevention of viral infections An ophthalmically acceptable composition comprising to the ocular region of a patient, the ophthalmically acceptable composition comprising water, a biguanide containing antimicrobial in an amount effective to treat viral infection. The invention further comprises administering the ophthalmically acceptable composition to the eye of a patient in need of treatment. ... 06/21/07 - 20070141091 - Biguanide ointment and method of treatment and prevention of infections An ophthalmically acceptable composition comprising a biguanide antimicrobial agent and an ointment base. The invention further comprises administering the ophthalmically acceptable composition to the eye of a patient in need of treatment. ... 06/21/07 - 20070141090 - Microemulsion preparation of high concentration propofol for anesthetic uses The invention provides a method and a composition for enhancing the dissolution and bioavailable properties of propofol (2,6 diisopropyl phenol) for use as an intravenously administered anesthetic in mammals. The method produces a self-microemulsifyable emulsion base composition that is utilized in the production of a water-based microemulsiori preparation. In a ... 06/21/07 - 20070141089 - Topical composition comprising terbinaf ine adn hydrocortisone The invention relates to topical pharmaceutical compositions comprising terbinafine and hydrocortisone. Said compositions exhibit beneficial antimycotic properties, especially against dermatophytes. ... 06/14/07 - 20070134280 - Thixotropic ingestible formulation to treat sore throat A thixotropic formulation includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water. ... 06/14/07 - 20070134279 - Fast-acting oral peptide pharmaceutical products A finished pharmaceutical product adapted for oral delivery of a physiologically active peptide agent, wherein the product comprises a therapeutically effective amount of the active peptide agent; at least one pharmaceutically acceptable pH-lowering agent; and at least one absorption enhancer effective to promote bioavailability of the active agent, wherein the ... 06/14/07 - 20070134278 - Aqueous dispersions and solutions of difficult to dissolve materials and methods of their preparation The present invention encompasses a method of preparing a ready-to-dissolve or ready-to-disperse composition of difficult to dissolve in water compounds and suspensions or aqueous solutions of difficult to dissolve in water compounds. ... 06/14/07 - 20070134277 - Pharmaceutical formulation for sulfur-containing drugs in liquid dosage forms The pharmaceutical formulations of the invention for masking the odor from the sulfur-containing active agent comprise at least one sulfur-containing active agent, an effective amount of at least one flavoring agent. Any flavoring agent or combinations of flavoring agents may be used in the pharmaceutical formulation of the invention. The ... 06/14/07 - 20070134276 - Microemulsions of retinoids, and pharmaceutical compositions containing them Disclosed are water-in-oil (W/O) microemulsions containing as active ingredient a retinoid, a phospholipid emulsifier, and possibly hyaluronic acid or salts thereof. ... 06/07/07 - 20070128231 - Erythropoietin solution formulation A stable pharmaceutical formulation of erythropoietin is disclosed which contains tris-(hydnox-ymethyl)-aminomethane as stabilizer, whereby the formulation does not contain amino acids or human serumalbumin. ... 05/24/07 - 20070116730 - Pharmaceutical compositions A method of providing systemic analgesia to cats, dogs and other small mammals by the ophthalmic administration of opioids is disclosed. Compositions for use in such a method are also disclosed. ... 05/24/07 - 20070116729 - Lyophilization process and products obtained thereby A lyophilization process which comprises dissolving a material in one or more solvents for said material to form a solution; forcing said material at least partially out of solution by combining the solution and a non-solvent for the material, which non-solvent is miscible with the solvent or solvents used and ... 05/24/07 - 20070116728 - Novel galenical system for active transport, method for preparation and use The invention relates to a novel galenical system for taste masking, protecting an active substance, in particular in an acid medium, modulating releasing properties, masking mucous irritability and toxicity of certain active substances, for preparing aqueous forms which have a masked taste, are stable and pH independent. Said invention also ... 05/17/07 - 20070110776 - In vitro methods for evaluating the in vivo effectivness of dosage forms of microparticulate or nanoparticulate active agent compositions Disclosed are in vitro methods for evaluating the in vivo redispersibility of dosage forms of poorly water-soluble active agents. The methods utilize media representative of in vivo human physiological conditions. ... 05/17/07 - 20070110775 - Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of an aptamer and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions. ... 05/10/07 - 20070104745 - Aqueous dispersions of crystalline polymers and uses Aqueous dispersions of crystalline polymers based on hydrophobic monomers, preferably on a mixture of hydrophobic and hydrophilic monomers which contains a crosslinking monomer, particularly side chain crystalline (SCC) polymers. The dispersions are useful for providing coatings on substrates, particularly on seeds (whose dormancy is thus extended) and on fibrous substrates, ... 05/10/07 - 20070104744 - Ophthalmic and contact lens solutions containing forms of vitamin b The present invention relates to improved ophthalmic solutions that employ select B vitamins; pyridoxine and its salts; and thiamine and its salts in order to more effectively preserve solutions and to reduce the degree to which cationic preservatives will deposit on contact lenses. Ophthalmic solutions are here understood to include ... 05/10/07 - 20070104743 - Formulations of fispemifene or a geometric isomer, a stereoisomer, a mixture of isomers, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, in combination with a pharmaceutically acceptable carrier. ... 05/10/07 - 20070104742 - Novel oral formulations of ospemifene or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, in combination with a pharmaceutically acceptable carrier. ... 05/10/07 - 20070104741 - Delivery of tetrahydrocannabinol A self-emulsifying drug delivery system to improve dissolution, stability, and bioavailability of drug compounds of dronabinol or other cannabinoids. The drug compound(s) are dissolved in an oily medium (e.g. triglycerides and/or mixed glycerides and/or free fatty acids containing medium and/or long chain saturated, mono-unsaturated, and/or poly-unsaturated free fatty acids) together ... 05/10/07 - 20070104740 - Self-microemulsifying drug delivery systems of a hiv protease inhibitor The present invention relates to pharmaceutical formulations of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate, salts, esters, polymorphic and pseudopolymorphic forms thereof, which are self-microemulsifying drug delivery systems and comprise as carrier a lipophilic phase, one or more surfactants, a hydrophilic solvent and a nucleation inhibitor. ... 05/03/07 - 20070098748 - Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction ... 05/03/07 - 20070098747 - Topical pharmaceutical composition for the treatment of inflammatory dermatoses Provided is a topical pharmaceutical composition for the treatment of inflammatory dermatoses, including acne vulgaris, together with methods for its use. The composition and methods involve the topical use of an active agent effective in the treatment of inflammatory dermatoses plus a permeation-enhancing base that, in one embodiment, gives the ... 05/03/07 - 20070098746 - Multi-layered coating technology for taste masking Various embodiments of the present invention relate to compositions and methods that have multi-layer coating technology that provide improved taste masking. This technology enables taste masked drug substances to withstand hydration due to saliva in the mouth and aqueous solutions. ... 04/26/07 - 20070092540 - Carboxylate-gated-nitroxide (cgn) compounds and compositions and methods of use thereof Carboxylic-gated-nitroxide (CGN) compounds and their esterified derivatives are discovered and disclosed as compositions and shown to have the potential in treating a variety of acute and chronic diseases and disorders resulting from reactive oxygen species (ROS) injury. Compositions for treating tissue damage from ROS injury containing CGN, or active derivatives ... 04/26/07 - 20070092539 - Method of preparing an aqueous meloxicam solution and aqueous solution thus produced A method of solubilizing a selective inhibitor active agent of cyclo-oxigenase-2 (COX-2), such as meloxicam, and a method of preparing an ophthalmic solution from the solubilized meloxicam for the treatment of distinct ocular affections are described. The invention also refers to an aqueous ophthalmic solution resulting from the method, said ... 04/19/07 - 20070087022 - Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of suspended particles coated with protein (which acts ... 04/12/07 - 20070082018 - Stabilized antimicrobial compositions and related methods of preparation Antimicrobial compositions and related methods as can be used to enhance stability and/or maintain antimicrobial activity. ... 04/12/07 - 20070082017 - Lipid compositions and methods of use The present invention relates to a composition comprising: a C12 to C24 branched or unbranched hydrocarbon; a mid-chain triglyceride; a C26 to C36 branched or unbranched hydrocarbon; a cholesteryl ester; an ester of a C10 to C24 fatty acid and a C10 to C20 alcohol; an ester of a C10 ... 04/12/07 - 20070082016 - Microemulsion preconcentrate comprising a renin inhibitor The present invention relates to pharmaceutical compositions for oral administration comprising a δ-amino-γ-hydroxy-ω-aryl-alkanoic acid amide renin inhibitors as the active ingredient. In particular, the present invention relates to galenic formulations in the form of microemulsion preconcentrates comprising the active ingredient and at least one absorption enhancing excipient which preconcentrates provide ... 04/05/07 - 20070077261 - Compositions and method for enhancing the solubility of ascorbic acid using solubilization enhancers A method for dissolving ascorbic acid in a nonaqueous alcohol solvent using a solubilization enhancer is described. The amount of ascorbic acid solubilized in the nonaqueous alcohol solvent containing the solubilization enhancer is greater than the amount of ascorbic acid that would be soluble in the nonaqueous alcohol solvent without ... 03/29/07 - 20070071779 - Compositions for delivering lipophilic agents to the intestinal mucosa and method of making thereof A composition for delivering lipophilic agents to intestinal mucosa and method of making and use thereof are disclosed. The composition comprises an aqueous solution of one or more short chained C2 to C6 fatty acids, and corresponding salts thereof, and one or more lipophilic agents dissolved in the aqueous solution. ... 03/29/07 - 20070071778 - Stable microemulsion concentrate for delivery of a bioactive biocide/disinfectant/fungicide/fragrance in an aqueous medium providing sustained release What is described herein is a stable microemulsion concentrate and composition for delivery of an active biocide/disinfectant in an aqueous medium providing sustained release of the active. The composition is effective against both bacteria and fungi. ... 03/29/07 - 20070071777 - Oil emulsion for postnatal hormone substitution The invention relates to a process for the preparation of hormone-containing oil emulsions (lipid emulsions), an isotonic oil emulsion obtainable by such process, and the use of the emulsion according to the invention for the preparation of a medicament for intravenous administration, especially for postnatal hormone substitution in premature babies ... 03/22/07 - 20070065469 - Liquid formulations with high concentration of human growth hormone (high) comprising glycine The present invention relates to liquid formulations of human growth hormone (hGH, somatropin) which are storage stable, show reduced or no crystallization on storage and are suitable for administration to the human or animal body. More particularly, the invention relates to liquid formulations of human growth hormone which are stable ... 03/08/07 - 20070053939 - Biguanide drug-containing jelly preparation The invention provides a biguanide drug-containing jelly preparation of which discomfort upon administration is decreased by the control of its harshness or bitterness. In addition, the preparation has stability and excellent ability for releasing a drug in the digestive tract. The biguanide drug-containing jelly preparation of the invention is characterized ... 03/01/07 - 20070048338 - Compositions and methods for surface treatment in medical and surgical procedures The present invention comprises compositions and methods for contemporaneously anesthetizing and antiseptically treating or pretreating anatomic surfaces for invasive surgical or treatment procedures. In particular, compositions and methods according to the present invention are used to treat ocular surfaces for intravitreal injections and other ophthalmic procedures. Compositions of the present ... 03/01/07 - 20070048337 - Aldol-crosslinked polymeric hydrogel adhesives Adhesives formed by reacting an oxidized polysaccharide with a poly(hydroxylic) compound derivatized with acetoacetate groups in the presence of a base catalyst are disclosed. The use of the adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, ... 02/22/07 - 20070042009 - Topical composition for delivery of salicylates The present invention provides a self-emulsifiable composition and a stable topical emulsion comprising same, which comprises salicylate, oils and surfactants and which does not require organic solvents. The invention also provides methods for manufacturing the compositions. The topical compositions of the invention can be used to enhance delivery of salicylates ... 02/22/07 - 20070042008 - Compositions containing phosphatidylcholine and essential fatty acids The invention discloses pharmaneutical compositions comprising a phospholipid formulation that is fluidized with an oil composition containing a pre-determined ratio of omega 6 and omega 3 fatty acids. In particular the invention discloses phosphatidylcholine compositions that are fluidized with a pre-determined ratio of linoleic acid and alpha linolenic acid. ... 02/22/07 - 20070042007 - Topical composition for delivery of salicylate esters The present invention provides a self-emulsifiable composition and a stable topical emulsion comprising same, which comprises salicylate esters, oils and surfactants and which does not require organic solvents. The invention also provides methods for manufacturing the compositions. The topical compositions of the invention can be used to enhance delivery of ... 02/22/07 - 20070042006 - Stable carprofen composition A stable solvent-based composition is described which is particularly useful in warm blooded animals such as dogs. The composition comprises a therapeutically effective amount of carprofen, one or more polyols, one or more stabilising agents and optionally, one or more co-solvents. ... 02/15/07 - 20070036831 - Nanoemulsion compositions having anti-inflammatory activity Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating ... 02/15/07 - 20070036830 - Container A container and more specifically a container such as a capsule used to deliver dosages of pharmaceuticals, medicines, vitamins, etc. to an individual is discussed. In one embodiment, the invention includes a container comprising: a cap; a body slidably engagable inside the cap; and a fluid gap positioned between the ... 02/15/07 - 20070036829 - Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye An ophthalmic composition is self-emulsifying. The composition includes oil globules having an average size of less than 1 micron dispersed in an aqueous phase. These globules include a surfactant component with one or two surfactants and a polar oil component. The surfactant component and the oil component are selected to ... 02/08/07 - 20070031460 - Pharmaceutical compositions of hydrophobic compounds This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions. ... 02/08/07 - 20070031459 - Oral suspension of prednisolone acetate The present invention relates to novel oral suspension formulation comprising prednisolone acetate, a pharmaceutically acceptable vehicle and a thickening agent. The present invention further provides a method of treating patients in need of prednisolone with the novel formulation. ... 02/01/07 - 20070026027 - Human chorionic gonadotropin (hcg) formulations for facilitating weight loss and body contouring The present invention relates to formulations of hCG for sublingual administration to mammals to facilitate weight loss and/or body contouring. Embodiments of the invention disclose administration of hCG formulations in combination with a low calorie diet and dietary supplements and, in some cases, with an exercise regime. Embodiments of this ... 02/01/07 - 20070026026 - Oral liquid losartan compositions The present invention is directed to improved oral liquid compositions that include losartan, or a pharmaceutically acceptable salt or metabolite thereof, and at least one pharmaceutically acceptable carrier in an amount sufficient to provide a pH of about 6 or higher. Processes of preparing such compositions and methods of administering ... 02/01/07 - 20070026025 - Topical ointment and method for making and using same A topical ointment comprises a base material of plasticized hydrocarbon gel and methylcellulose in which are dispersed a plurality of microbubbles containing liquid. The microbubbles containing liquid are encapsulated by the base material to form microencapsulations which are dispersed in the base material to form a hydrogel. Application of the ... 02/01/07 - 20070026024 - Compositions and methods for emulsifying a pefluorocarbon with an oxygen-carrying surfactant A physiologically acceptable perfluorocarbon emulsion composition that includes perfluorodecalin and an oxygen-carrying fluorinated surfactant forming a stable emulsion in a continuous aqueous phase. The oxygen-carrying fluorinated surfactant may be fractionated to increase its physiological compatibility, and may further include a fatty acid radical perfluorinated to increase its oxygen-carrying capacity. The ... 01/25/07 - 20070020300 - Recreational water treatment employing singlet oxygen Recreational or process water can be treated by uniformly dissolving in the water a singlet oxygen-generating photosensitizer selected from the group consisting of condensed aromatic compounds, acridine dyes, coumarin dyes, crystal violet, fluorene derivatives, porphyrin derivatives, chlorins, thiazine dyes, thioketones, xanthene dyes, or by uniformly dissolving in the water a ... 01/25/07 - 20070020299 - Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid An inhalable formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use ... 01/25/07 - 20070020298 - Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid An inhalable formulation containing SAE-γ-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use ... 01/18/07 - 20070014821 - Method of cancer screening; method of cancer treatment; and method of diabetes treatment A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive administering a needle biopsy; if the result is positive administering a PET scan; if the result is positive administering a blood ... 01/18/07 - 20070014820 - Opioid formulations The present invention provides high-concentration formulations of opioids such as fentanyl or fentanyl congeners. The formulation of the invention comprises fentanyl or a fentanyl congener in concentrations significantly in excess of conventional formulations, e.g., on the order about 2-fold to about 10,000-fold greater than conventional formulations, e.g., currently commercially available ... 01/18/07 - 20070014819 - Method of emulsifying phytosterol by natural saponin,emulsion prepared thereby and water dispersible phytosterol powder product Method of emulsifying phytosterol by natural saponin is disclosed including mixing an oil phase having phytosterol dissolved therein and an aqueous phase having a natural hydrophilic surfactant (saponin) therein to obtain an emulsion of phytosterol. A water dispersible phytosterol powder product can be formed by drying the emulsion, which is ... 01/18/07 - 20070014818 - Liquid formulations with high concentration of human growth hormone (hgh) comprising 1,2-propylene glycol The present invention relates to liquid formulations of human growth hormone (hGH, somatropin) which are storage stable, show reduced or no crystallization on storage and are suitable for administration to the human or animal body. More particularly, the invention relates to liquid formulations of human growth hormone which are stable ... 01/11/07 - 20070009559 - Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same A free-flowing solid formulations of drugs or pharmaceutical agents which have poor aqueous solubility are obtained by admixing a liquid or gel composition that includes 1 to 30 percent by weight of the drug, 5 to 60 percent by weight of a surfactant, 10 to 40 percent by weight of ... 01/11/07 - 20070009558 - Sugar-free storage-stable antihistaminic syrups New and improved antihistaminic syrups are disclosed. ... 01/11/07 - 20070009557 - Moldable implant material A moldable implant material is described which is characterized in that a biodegradable or biocompatible monofilament or polyfilament thread is formed e.g. of polyester, polyamide, a corrodible iron alloy, magnesium, magnesium alloys, polysaccharides, polysaccharide derivatives, proteins, and/or protein derivatives or of combinations of these materials in such a way that, ... 01/04/07 - 20070003582 - Medicine for the treatment of acne and for reversing the signs of age and sun damage and method for using same A chemical compound and a method for its use as a topical medication that can reverse the effects of sun-damage, reverse the signs of aging, demonstrate anti-scarring properties and allow for the treatment of acne while still permitting the patient the ability to simultaneously expose the affected area to the ... 01/04/07 - 20070003581 - Microemulsion for cosmetic or pharmaceutical use containing an active ingredient The invention relates to a transparent microemulsion comprised of a surfactant or emulsifier based on polyethylene glycol, a first cosurfactant (or coemulsifier) based on polyglycerol, a second cosurfactant (or coemulsifier) based on monoesters, an aqueous or hydrophilic phase, and may or may not include an active for delivery that can ... 12/28/06 - 20060292191 - Use of nanodispersions in pharmaceutical end formulations A nanodispersion comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in pharmaceutical end formulations, the nanodispersion being obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and (β) adding the liquid obtained in step (α) to the ... 12/28/06 - 20060292190 - Amelioration of vitrectomy-induced cataracts Methods to prevent, inhibit, or slow the development of vitrectomy-induced cataracts are disclosed. The methods comprise administering to the eye of a subject a composition comprising an ophthalmologically acceptable carrier or diluent and at least one hydroxylamine compound in a therapeutically sufficient amount to prevent, inhibit, or slow the development ... 12/28/06 - 20060292189 - Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution The invention provides an ophthalmic solution with a flavoring agent as a dosing indicator and a method for indicating dosage of an ophthalmic solution. To indicate dosage, a flavoring agent is added to an ophthalmic solution in an amount correlated to the dosage of the ophthalmic solution to be used. ... 12/28/06 - 20060292188 - Ophthalmic solution with a flavoring agent The invention provides an ophthalmic solution with at least one flavoring agent to mask flavors in the solution or add flavor to the solution. The flavoring agent can be a sweet flavoring agent (sweetener), or combinations of a sweetener with a sour flavoring agent or a bitter flavoring agent or ... 12/28/06 - 20060292187 - Nerve construct containing living stretch-grown nervous tissue The present invention relates to mechanically elongated neurons and provides useful compositions, devices and methods for treating a nerve lesion using such mechanically elongated neurons. ... 12/28/06 - 20060292186 - Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs A pharmaceutical composition in a form of an anhydrous self-nanoemulsifying oily formulation comprising: one or more therapeutic agent(s) which have low solubility in water or are water-insoluble, vitamin E, one co-solvent selected from propylene glycol and ethanol and mixture thereof one surfactant selected from tyloxapol and from mixture of tyloxapol ... 12/28/06 - 20060292185 - Topical skin preparations for treatment of skin aging comprising a testosterone ester The present invention concerns Topical skin preparations for the use in the prevention of atrophy and aging of the skin, comprising a testosterone ester with an esterifying acid having between six to eleven carbon atoms. ... 12/28/06 - 20060292184 - Bioadhesive liquid composition which is substantially free of water A liquid composition for adherence to a bodily surface, notably to a bodily surface, especially a mucosal surface, comprises water-swellable polymer particles suspended in a water-miscible liquid diluent, wherein the liquid diluent is substantially free of water or includes an amount of water insufficient to fully swell the polymer particles. ... 12/28/06 - 20060292183 - Microemulsions as precursors to solid nanoparticles The preparation of novel microemulsions to be used as precursors for solid nanoparticles is described. The microemulsion precursors consist of either alcohol-in-fluorocarbon microemulsions, liquid hydrocarbon-in-fluorocarbon microemulsions, or liquid hydrocarbon-in-water microemulsions. The formed solid nanoparticles have diameters below 200 nanometers and can be made to entrap various materials including drugs, magnets, ... 12/21/06 - 20060286132 - Use of stellate ganglion block for the treatment of sexual dysfunction The present invention is directed to a method for the treatment of a patient suffering from sexual dysfunction and other symptoms comprising the step of administering a stellate ganglion block to the patient to alleviate the symptoms. The stellate ganglion block may be followed by a sympathectomy to provide permanent ... 12/21/06 - 20060286131 - Use of stellate ganglion block for the treatment of hot flashes and other conditions The present invention is directed to a method for the treatment of a patient suffering from hot flashes and other symptoms comprising the step of administering a stellate ganglion block to the patient to alleviate the symptoms. The stellate ganglion block may be followed by a sympathectomy to provide permanent ... 12/21/06 - 20060286130 - Sterile gelling agents This invention is directed to sterile gelling agents, which retain their physico-chemical properties so that they can be used in drug delivery systems. Also described are the processes for obtaining a sterile gelling agent(s). ... 12/21/06 - 20060286129 - Oral glp-1 formulations The present invention provides phamaceutical compositions comprising at least one delivery agent and GLP-1. These pharmaceutical compositions facilitate the oral delivery of GLP-1, providing improved (e.g. increased) bioavailability of GLP-1 compared to administration of GLP-1 without a delivery agent. ... 12/14/06 - 20060280761 - Nanofluidized b-12 composition and process for treating pernicious anemia A method of manufacturing a stable nanosuspension for delivery of a biologically active agent, particularly vitamin B-12, into the bloodstream of a subject is disclosed. A nanofluidizable mixture containing vitamin B-12 is initially formed and processed via a nanofluidization process to form the stable nanosuspension, which may be administered via ... 12/14/06 - 20060280760 - Assortment of personal care products having synergistic identifiers communicating products to be purchased together A line of personal care products comprising a first product comprising a first identifier and a second product comprising a second identifier wherein said first identifier and said second identifier are synergistic wherein said first identifier and said second identifier together communicate that said first product and said second product ... 12/07/06 - 20060275331 - Pharmaceutical composition, method of manufacturing and therapeutic use thereof The invention relates to a pharmaceutical composition prepared by freeze-drying in vacuo, containing oxaliplatin as the active component and a pharmaceutically acceptable carrier, wherein the carrier is at least one alcoholic sugar of non-animal origin, the weight ratio of oxaliplatin to the alcoholic sugar of non-animal origin or alcoholic sugars ... 11/30/06 - 20060269579 - Compositions for treating osteoarthritis A method and composition for treating osteoarthritis with ion-channel regulators is disclosed. The ion-channel regulators are used alone or in combination with other osteoarthritis treatment agents, including but not limited to injectable agents such as viscosupplements and steroids. A composition comprising one or more ion-channel regulator(s) and one or more ... 11/30/06 - 20060269578 - Microemulsions and its use for preventing airway diseases The invention relates to novel microemulsions comprising a non-polar lipid, at least one polar solvent, a surfactant, and a polar lipid. A microemulsion of these ingredients provides an environment that substantially encloses airborne particles, and it can be used for entrapping such particles. The inventive microemulsions are especially adapted for ... 11/23/06 - 20060263397 - Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same A free-flowing solid formulations of drugs or pharmaceutical agents which have poor aqueous solubility are obtained by admixing a liquid or gel composition that includes 1 to 30 per cent by weight of the drug, 5 to 60 per cent by weight of a surfactant, 10 to 40 per cent ... 11/23/06 - 20060263396 - Stable hydroalcoholic compositions A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system comprised of at least one emulsifier present in at least 0.05% by weight wherein the composition ... 11/23/06 - 20060263395 - Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease The present invention relates to the enhancement of bioavailability of chemotherapeutic agents for the treatmnet of disease. In particular the present invention relates to a method of enhancing the bioavailability of a chemotherapeutice agent comprsing the step of administering to a submect in need thereof a therapeutically effective amount of ... 11/23/06 - 20060263394 - Environmental raw material capable of providing impact resistance, method of producing the same, and moldings A resin composition containing a crystal structure of poly(lactic acid), which is obtained by melt-kneading 30 to 99 mass % of poly(lactic acid) and 70 to 1 mass % of a copolymer having a functional group reactive with the poly(lactic acid); a method of producing the same; and moldings. ... 11/23/06 - 20060263393 - Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the the urinary tract during urological diagnostic, interventional, surgical and other medical procedures. One disclosed composition comprises ketoprofen and nifedipine in a liquid irrigation carrier, and includes a solubilizing agent, stabilizing ... 11/16/06 - 20060257435 - Concentrated water-dispersible vitamin compositions A water-dispersible vitamin composition containing Vitamins A, D3 or E, or a precursor thereof, an alkyl lactate and an emulsifier and is substantially free of water. ... 11/16/06 - 20060257434 - Production of emulsions of pharmaceutical compositions Disclosed are methods of producing an emulsion comprising determining a desired final pH of the emulsion, mixing an oil, surfactant, stabilizer, and a water-insoluble pharmaceutical, adjusting the pH of the mixture, and homogenizing the mixture, such that the starting pH of the mixture, the rotation speed of the homogenizer, and ... 11/16/06 - 20060257433 - Formulation The invention relates to sterile pharmaceutical compositions for parenteral administration which comprise an oil-in-water emulsion in which a free radical scavenging sedative agent dissolved in an omega-3 rich water-immiscible solvent, is emulsified with water and stabilised by means of a surfactant, the composition being suitable either directly or after dilution ... 11/16/06 - 20060257432 - Pharmaceutical formulations of xanthogenates and inhibitors of viral nucelic acid replication wherein R1 represents an optionally substituted aryl or alkyl residue and R2 represents a metal atom, an optionally substituted alkyl, alkoxy, amino or ammonium group or halogen, and an inhibitor of viral nucleic acid replication such as e.g. aciclovir, valaciclovir, penciclovir, famciclovir, and optionally a carrier substance reducing the irritating ... 11/09/06 - 20060251685 - Stable ophthalmic oil-in-water emulsions with omega-3 fatty acids for alleviating dry eye An ophthalmic composition includes oil globules dispersed in an aqueous phase. The globules include a surfactant component, a polar oil component that includes an Omega-3 fatty acid and a viscosity modifying agent. The surfactant to oil ratio produces an average size of globules of about 0.1 microns or less. The ... 11/09/06 - 20060251684 - Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided. ... 11/02/06 - 20060246096 - Nanoparticles from biopolymers Methods are disclosed for preparing core-shell polymers of poly-γ-glutamic acid. The final products of the present invention are useful as drug delivery systems, for gene therapy, magnetic resonance imaging as well as in encapsulation technology. A method of forming a poly-γ-glutamic acid (PGA) useful in the formation of core shell ... 10/26/06 - 20060240052 - Ketoprofen compositions and methods of making them A wide variety of pharmaceutically and commercially acceptable dosage forms of ketoprofen are prepared by dissolving ketoprofen in pharmaceutically acceptable solvents. ... 10/26/06 - 20060240051 - Eutectic blends containing a water soluble vitamin derivative An eutectic composition having from about 10 to about 90 weight % of a first component comprising a pharmaceutically acceptable substituted C6-C10 aryl compound wherein the aryl moiety includes a straight or branched moiety selected from the group consisting of C1-C12 alkyl, C1-C12 alkoxy, C2-C6 alkanoyloxy, hydroxy, carboxy, carboxy substituted ... 10/26/06 - 20060240050 - Stable clozapine suspension formulation A physicochemically stable aqueous composition including clozapine suspension. ... 10/26/06 - 20060240049 - Anti-protozoal compositions comprising diclazuril The present invention relates to compositions suitable for oral, transdermal or parenteral (e.g. intranasal, intramuscular, subcutaneous or intravenous) administration, wherein the composition is comprised of at least one anti-protozoal agent dissolved in a mixture of an alcohol based solvent-system, an emulsifier-system and a base-system. Also provided is a method for ... 10/19/06 - 20060233844 - Method for the delivery of a biologically active agent A method of manufacturing a stable nanosuspension for delivery of a biologically active agent into the bloodstream of a subject is disclosed. A microfluidizable mixture is initially formed and processed via a microfluidization process to form the stable nanosuspension, which may be administered via the buccal mucosa or other suitable ... 10/19/06 - 20060233843 - Treatment of psychosis with a muscarinic m1 receptor ectopic activator A muscarinic M1 receptor ectopic activator, such as a muscarinic M1 receptor allosteric potentiator or a muscarinic M1 receptor ectopic agonist is useful, alone or in combination with other antipsychotic agents, for treating or preventing psychosis, such as a schizophrenic disorder or psychosis in Alzheimer's disease or bipolar disorder, for ... 10/19/06 - 20060233842 - Microemulsion composition for oral administration of biphenyldimethyldicarboxylate A microemulsion composition comprising biphenyldimethyldicarboxylate (DDB), a co-surfactant, a surfactant and an oil provides an improved stability and a high in vivo bioavailability of biphenyldimethyldicarboxylate when orally administered. ... 10/12/06 - 20060228385 - Sustained release of microcrystalline peptide suspensions The invention relates to a microcrystalline aqueous suspension of a peptide salt selected from the group consisting of Ac—D—Nal—D—Cpa—D—Pal—Ser—Tyr—D—Hci—Leu—Ilys—Pro—D—Ala—NH2trifluoroacetate and Ac—D—Nal—D—Cpa—D—Pal—Ser—Tyr—D—Hci—Leu—Ilys—Pro—D—Ala—NH2 sulfate. The invention also relates to methods of preparing the suspension, lyophilized compositions formed from the suspensions, and sustained release formulations that include the suspensions. ... 10/12/06 - 20060228384 - Control of biofilm with a biofilm inhibitor The present invention provides methods for preventing, reducing, inhibiting or removing bacterial biofilm. The present invention also provides methods for controlling acne and chronic bacterial infections. The present invention further provides a method for identifying agents that prevent, reduce, inhibit or remove bacterial biofilm. ... 10/12/06 - 20060228383 - Stable pharmaceutical composition of fluoroether compound for anesthetic use method for stabilizing a fluoroether compound, use of stabilizer agent for precluding the degradation of a fluoroether compound The present invention has as objective the stabilization of a fluoroether compound against degradation by acid substances. The stabilizers proposed are selected among propylene glycol, polyethylene glycol, hexylene glycol, 1,3-butylene glycol and a saturated cyclic alcohol preferably menthol and are used for preparing stable pharmaceutical compositions of a fluoroether compound. ... 10/05/06 - 20060222669 - Stannsoporfin compositions and administration Pharmaceutical compositions including stannsoporfin, drug products incorporating pharmaceutical compositions, methods of making pharmaceutical compositions, and methods of treating hyperbilirubinemia with drug products and compositions are disclosed. ... 10/05/06 - 20060222668 - Stannsoporfin compositions, drug products and methods of manufacture Pharmaceutical compositions including stannsoporfin, drug products incorporating pharmaceutical compositions, methods of making pharmaceutical compositions, and methods of treating hyperbilirubinemia with drug products and compositions are disclosed. ... 09/28/06 - 20060216317 - Delivery of polynucleotide agents to the central nervous system The present invention provides a method for delivering polynucleotide agents, particularly oligonucleotides, to the CNS of a mammal by way of a neural pathway originating in the nasal cavity or through a neural pathway originating in an extranasal tissue that is innervated by the trigeminal nerve. ... 09/21/06 - 20060210592 - Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis An oral preparation consisting of a non-systemic antibiotic and a proton pump blocker used for prevention of aspiration pneumonia and sepsis; and a method of prevention of aspiration pneumonia and/or sepsis by orally administering to a subject in need of such treatment a composition containing a therapeutically effective amount of ... 09/14/06 - 20060204526 - Emulsive composition containing dapsone The present invention relates to a topical, emulsive composition containing Dapsone or its derivative. The inventive composition incorporates emollients and Dapsone or its derivative in a stable emulsion. The stability is achieved through the use of a combination of certain surfactant mixtures and an enhancer providing solubility of the Dapsone. ... 09/07/06 - 20060198856 - Ibuprofen suspension stabilized with docusate sodium A stabilized aqueous pharmaceutical ibuprofen composition of ibuprofen stabilized with a stabilizing effective amount of docusate sodium. ... 08/31/06 - 20060193878 - Method of preparing gas delivering perfluorocarbon emulsions with non-fluorinated surfactants The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic ... 08/31/06 - 20060193877 - Compositions and methods of making sustained release liquid formulations The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or about, the density of the ... 08/24/06 - 20060188532 - Mixture for transdermal delivery of low and high molecular weight compounds The present invention relates to the discovery of a transdermal delivery system that can deliver high molecular weight pharmaceuticals and cosmetic agents to skin cells. A novel transdermal delivery system with therapeutic and cosmetic application and methods of use of the foregoing is disclosed. ... 08/24/06 - 20060188531 - Mixture for transdermal delivery of low and high molecular weight compounds The present invention relates to the discovery of a transdermal delivery system that can deliver high molecular weight pharmaceuticals and cosmetic agents to skin cells. A novel transdermal delivery system with therapeutic and cosmetic application and methods of use of the foregoing is disclosed. ... 08/24/06 - 20060188530 - Bile preparations for gastrointestinal disorders The present disclosure relates to methods and compositions to offset, ameliorate and/or alleviate one or more unwanted and/or adverse gastrointestinal effects. For example, in some embodiments, the present disclosure relates to compositions that include a bile acid, a carbohydrate and/or a pharmaceutical compound, wherein the pharmaceutical is associated with an ... 08/24/06 - 20060188529 - Stable compositions of fenofibrate with fatty acid esters A pharmaceutical composition in unit dose form of fenofibrate and a solvent system of fatty acid esters, wherein the fenofibrate is substantially dissolved in the solvent system. ... 08/24/06 - 20060188528 - Spreadable warming lubricant A substantially anhydrous, spreadable warming lubricant composition comprising a mixture of glycerin, a polyhydric alcohol, and a non-ionic surfactant, the viscosity of the composition being less than that of glycerin but greater than that of the polyhydric alcohol, thereby promoting formation of a useful thin layer on a surface with ... 08/17/06 - 20060182771 - Formulations for ocular treatment Diseases and conditions associated with tissues of the body, including tissues in the eye, can be effectively treated by administering therapeutic agents to those tissues. Described herein are self-emulsifying formulations and methods for delivering therapeutic agents to such tissues. A self-emulsifying formulation may be delivered to an aqueous medium of ... 08/17/06 - 20060182770 - Cosmetic and cosmeceutical compositions for restoration of skin barrier function Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and/or in a pathological condition. In general, divalent cations such as calcium ions and/or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations ... 08/03/06 - 20060171970 - Pharmaceutical formulation delivery system The invention relates to the development of a simple and inexpensive oral delivery system for customized pharmaceutical formulations for treating patients having conditions such as HIV/AIDS, cancer, and heart disease. The system includes a) a plurality of prepackaged pharmaceutical formulations containing at least two pharmacologically active ingredients in periodic (e.g., ... 08/03/06 - 20060171969 - Oral pharmaceutical forms of liquid drugs having improved bioavailability The present invention relates to new pharmaceutical compositions for the administration of liquid drugs in solid oral forms, said compositions comprising one or more active ingredients, one or more surface-active agents and optionally a co-surfactant and/or an absorption enhancer absorbed on a solid inert carrier. ... 07/27/06 - 20060165734 - Novel method of deodorization for fat odor and composition obtained by the same The present invention provides a novel deodorizing composition and a novel deodorizing method. A composition is provided in which oily odors have been deodorized by containing a xanthophyll or other carotenoid in an oil such as a highly unsaturated fatty acid or compound containing a highly unsaturated fatty acid as ... 07/27/06 - 20060165733 - Liquid formulations with high concentration of hunan growth hormone (hgh) comprising phenol The present invention relates to liquid formulations of human growth hormone (hGH, somatropin) which are storage stable, show reduced or no crystallization on storage and are suitable for administration to the human or animal body. More particularly, the invention relates to liquid formulations of human growth hormone which are stable ... 07/20/06 - 20060159713 - Bendamustine pharmaceutical compositions The present invention provides pharmaceutical formulations of lyophilized bendamustine suitable for pharmaceutical use. The present invention further provides methods of producing lyophilized bendamustine. The pharmaceutical formulations can be used for any disease that is sensitive to treatment with bendamustine, such as neoplastic diseases. ... 07/20/06 - 20060159712 - Lipid particles comprising bioactive agents, methods of preparing and uses thereof The present invention relates to a non-liposomal lipid particle comprising an amphiphile-coated complex of a hydrophobic bioactive agent and an inverted hexagonal phase forming lipid, and methods of preparing and kits thereof. ... 07/20/06 - 20060159711 - Therapeutic agent for hemorrhoidal disease An external preparation containing acetylsalicylic acid or its pharmaceutically acceptable salt as an active ingredient for treating anal diseases having therapeutic activity on hemorrhoids (internal hemorrhoid, external hemorrhoid), hemorrhoidal disease owing to anal fissure and other anal diseases together with activity on pain and pruritus. ... 07/13/06 - 20060153885 - Dry eye treatment This invention relates to an emulsion composition for the formation of an artificial tear film over the ocular surface of the eye capable of providing mechanical lubrication for the ocular surface while reducing evaporation of fluid therefrom. The emulsion is desirably in the form of a meta stable emulsion and ... 07/06/06 - 20060147483 - Hydrogel string medical device A hydrogel string that is useful as a medical device and a method for forming a hydrogel string that utilizes a delivery device in which gelation of a prepolymer is initiated to form a hydrogel, which is then extruded from the device as the hydrogel string. ... 07/06/06 - 20060147482 - Oral liquid pharmaceutical composition of leukotriene antagonists An oral liquid pharmaceutical composition of leukotriene antagonists is described and is used an anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agent. The composition is a buffer solution with the Montelukast or its pharmaceutically acceptable salt. The pH value of the buffer solution is between about 7 and 11. The buffer solution ... 07/06/06 - 20060147481 - Ketoprofen powder for oral use A readily water-soluble ingestible form of ketoprofen is provided by the reaction of ketoprofen and any edible weak base to yeild a palatable, stable, safe pharamaceutical solution for mass medication of animals. Any edible weak base such as sodium bicarbonate may be used with ketoprofen in a ratio of 10 ... 07/06/06 - 20060147480 - Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant The invention relates to the field of pharmaceutical formulations of follicle-stimulating hormone (FSH), luteinising hormone (LH), and mixtures of FSH and luteinising hormone (LH), and to methods of producing such formulations. The invention provides a liquid or freeze-dried formulation of FSH, or LH, or FSH and LH comprising a surfactant ... 07/06/06 - 20060147479 - Angiogenic medical cyanoacrylate adhesive Tissue adhesive comprising a cyanoacrylate in combination with an angiogenic factor such as butyric acid or a derivative or a precursor thereof. ... 06/29/06 - 20060140991 - Pharmaceutical preparations having an improved solubility The present invention provides a method for producing a pharmaceutical preparation having an improved solubility, which comprises the steps of forming a micelle by dissolving a poorly-soluble drug having the ability to form the micelle into water; and fixing the micelle structure which is formed with the poorly-soluble drug, by ... 06/29/06 - 20060140990 - Composition for topical treatment of mixed vaginal infections A pharmaceutical composition comprises (a) an antibacterial agent in an antibacterially effective amount, illustratively comprising clindamycin or a pharmaceutically acceptable salt or ester thereof, and (b) an antifungal agent in an antifungally effective amount, illustratively comprising butoconazole or a pharmaceutically acceptable salt or ester thereof. The composition is adapted for ... 06/29/06 - 20060140989 - Pharmaceutical formulations New and improved antihistaminic syrups are disclosed. ... 06/29/06 - 20060140988 - Visco-supplement composition and methods The present invention relates to methods and depot emulsion compositions for delivery of visco-supplements. ... 06/29/06 - 20060140987 - Aqueous compositions with poorly water soluble compounds There is provided an aqueous composition comprising at least one poorly water soluble compound and at least one pH-sensitive dispersed polymer. Also provided is a method of preparing an aqueous composition, comprising the step of preparing a mixture by mixing such ingredients, where the viscosity of the mixture is less ... 06/29/06 - 20060140986 - Anesthetic composition for topical administration It comprises a mixture of lidocaine, prilocaine and tetracaine, or their pharmaceutically acceptable salts. The preferred composition comprises the following components in the indicated approximate w/w percentages: 1.5% of lidocaine base; 1.5% of prilocaine base; 4% of tetracaine base; 10% of methylpynrolidone; 2% of dimethyl sulfoxide; 0.08% of topical hyaluronidase; ... 06/29/06 - 20060140985 - Lansoprazole formulations and related processes and methods The invention provides novel liquid lansoprazole formulations comprising lansoprazole and an excipient system, wherein: (a) the concentration of lansoprazole in the formulations ranges from about 0.3 mg/mL to about 50 mg/mL; (b) the excipient system comprises either a single excipient, or a combination of two to four compositionally distinct excipients; ... 06/29/06 - 20060140984 - Cosmetic and pharmaceutical foam The invention relates to an alcohol-free cosmetic or pharmaceutical foam carrier comprising water, a hydrophobic solvent, a foam adjuvant agent, a surface-active agent and a water gelling agent. The cosmetic or pharmaceutical foam carrier does not contain aliphatic alcohols, making it non-irritating and non-drying. The alcohol-free foam carrier is suitable ... 06/22/06 - 20060134151 - Novel sulfamide derivatives and cosmetic use thereof The invention also relates to compounds of general formula (II) ... 06/22/06 - 20060134150 - Submicron suspensions with polymorph control The present invention provides a method for preparing a suspension of a pharmaceutically active compound, the solubility of which is greater in a water miscible first organic solvent than in a second solvent which is aqueous, The process includes the steps of: (i) dissolving a first quantity of the pharmaceutically ... 06/22/06 - 20060134149 - Methods for treatment of inflammatory diseases An improved method of treating skin diseases comprises applying to the skin of a patient suffering such a skin disease an allantoin-containing composition in a therapeutically effective quantity. The allantoin-containing composition is an oil-in-water emulsion that includes allantoin and an emulsifier system that includes at least one emulsifier that is ... 06/22/06 - 20060134148 - Aqueous sustained-release drug delivery system for highly water-soluble electrolytic drugs The present invention relates to liquid sustained release suspension dosage forms comprising ionized forms of water-soluble drugs. In particular, the invention encompasses a liquid form controlled release drug composition comprising a dispersed phase comprising an ion-exchange matrix drug complex comprising a pharmaceutically acceptable ion-exchange matrix and a water-soluble electrolytic drug ... 06/22/06 - 20060134147 - Cosmetic compositions having carnitine creatinate and methods for using There is a topical composition having carnitine creatinate and a cosmetically acceptable vehicle. There is also provided a method for improving the aesthetic appearance of skin. There is also provided a method for inhibiting the induced lipid synthesis in skin. There is also provided a method for inhibiting the formation ... 06/22/06 - 20060134146 - Stable dispersion of solid particles comprising a water-insoluble pyrazine compound Also claimed are stable dispersions prepared by the process, solid particles prepared by the process and use of such particles. ... 06/22/06 - 20060134145 - Propofol-containing fat emulsions The present invention provides a propofol-containing fat emulsion comprising propofol, an oily component, and an emulsifier, and further comprising a predetermined amount of a stabilizer, such as phosphatidylglycerol in which a specific fatty acid is a constituent fatty acid component. The present invention also provides a pain-relieving propofol-containing fat emulsion, ... 06/22/06 - 20060134144 - Mucoadhesive composition and formulation for solubilization of insoluble drugs and preparation method thereof The present invention relates to a novel mucoadhesive composition for solubilization of insoluble drugs; its formulation including pharmaceutical compounds; and the preparation methods thereof wherein said solubilizing composition comprises 4˜90% by weight of at least one selected from the monoglycerides and 0.01˜90% by weight of at least one oil. The ... 06/15/06 - 20060127423 - Organic compounds Pharmaceutical formulations comprising an epothilone in the form of an infusion concentrate or a lyophilised composition, and methods of administration of an epothilone in suitable form for parenteral administration. ... 06/15/06 - 20060127422 - Boron nitride particles of spherical geometry and process for making thereof A low viscosity filler boron nitride agglomerate particles having a generally spherical shape bound together by an organic binder and to a process for producing a BN powder composition of spherically shaped boron nitride agglomerated particles having a treated surface layer which controls its viscosity. ... 06/15/06 - 20060127421 - Treatment using d-threo methylphenidate Methods for treating a disease responsive to the administration of methylphenidate and/or one or more isomers thereof, said method comprising identifying a patient suffering from a disease or disorder having a family history or diagnosis of tics or Tourette's Syndrome and administering to said patient a therapeutically effective amount of ... 06/15/06 - 20060127420 - Paclitaxel composition for the intravesical treatment of bladder tumor and preparation method thereof The present invention relates to a paclitaxel composition and the preparation methods thereof for the treatment of bladder cancer wherein said paclitaxel composition comprises 4˜90% by weight of at least one selected from the monoglycerides, 0.01˜90% by weight of at least one oil, 0.01˜90% by weight of at least one ... 06/08/06 - 20060121069 - Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins A method for treating hair loss in mammals uses compositions containing prostaglandins analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth. ... 06/08/06 - 20060121068 - Boron nitride particles of spherical geometry and process for making thereof A low viscosity filler boron nitride agglomerate particles having a generally spherical shape bound together by an organic binder and to a process for producing a BN powder composition of spherically shaped boron nitride agglomerated particles having a treated surface layer which controls its viscosity. In one embodiment, the composition ... 06/08/06 - 20060121067 - Menthol-containing preparation It is known that L-menthol controls smooth muscle contraction. In order to use L-menthol in practice as a digestive tract contraction inhibiting agent in digestive tract endoscopy, it is required to devise means of giving a formulation in which an L-menthol-containing formulation remains stable and transparent or little cloudy over ... 06/08/06 - 20060121066 - Sucralose formulations to mask unpleasant tastes The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH ... 06/01/06 - 20060115501 - Homogeneously formulating microdosed active principles A microdose of at least one active principle is essentially homogeneously formulated within at least one excipient therefor, via the following steps: 1. weighing the at least one active principle in a receptacle lined with a petroleum jelly; 2. encapsulating the active principle with additional petroleum jelly; 3. introducing the ... 06/01/06 - 20060115500 - Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent This invention relates to a semisolid ophthalmic composition, in particular an ointment, comprising (1) an ophthalmic drug, e.g. a staurosporine derivative, (2) an ointment base and (3) an agent for dispersing and/or dissolving said drug in the ointment base, selected from a polyethylene-glycol), a polyethoxylated castor oil, an alcohol having ... 05/18/06 - 20060105001 - Smart drug delivery system The present invention provides prodrug and multi-prodrug complexes comprising drugs specifically bound to synthetic receptors in such a manner that active drug becomes available only in the presence of a targeted pathophysiologic receptor. Methods for preparation and use of these prodrug complexes in drug delivery systems are also provided. ... 05/18/06 - 20060105000 - Compositions for treating infected skin and mucous membrane comprising an anti-microbial agent and an essential oil The invention provides a composition of matter for treating infected skin and mucousal membranes, said composition comprising at least one anti-microbial drug; and at least one essential oil, in combination with a substantially, alcohol-free carrier system, said carrier being selected from a liquid carrier or a semi-solid carrier, said carrier ... 05/18/06 - 20060104999 - Composition for solubilization of paclitaxel and preparation method thereof The present invention relates to a paclitaxel composition and the preparation methods thereof to solubilize paclitaxel wherein said composition comprises 4˜90% by weight of at least one selected from the monoglycerides, 0.01˜90% by weight of at least one oil and 0.01˜20% by weight of paclitaxel. Also the present invention relates ... 05/18/06 - 20060104998 - Substituted 4-aryl-4h-pyrrolo[2,3-h]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof The present invention is directed to substituted 4H-chromenes and analogs thereof, represented by the Formula (I): wherein R1, R3-R5, A, D, Y and Z are defined herein. The present invention also relates to the discovery that compounds having Formula (I) are activators of caspases and inducers of apoptosis. Therefore, the ... 05/18/06 - 20060104997 - Monoterpene compositions and uses thereof The present invention relates to pharmaceutical compositions and methods for the mucosal and oral administration of monoterpenes and derivatives thereof. The compositions of this invention further comprise one or more surfactants and cosolvents and are in the form of self-emulsifying compositions. The compositions of the invention may further comprise water-insoluble ... 05/11/06 - 20060099230 - Novel formulations of eprosartan with enhanced bioavailability The invention relates to the composition of a novel formulation of eprosartan with enhanced bioavailability. The formulation comprises of eprosartan or a salt, solvate, or hydrate thereof, a solubilizer, and an emulsifier. A process for manufacturing, and methods of using the formulation to block angiotensin II receptors and to treat ... 05/04/06 - 20060093632 - Compositions for controlled delivery of pharmaceutically active compounds The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal by injection. When the pharmaceutical compositions are administered to an animal by injection, they form a ... 05/04/06 - 20060093631 - Dye-free pharmaceutical suspensions and related methods A dye-free pharmaceutical suspension having a therapeutically effective amount of a first active agent consisting essentially of a first substantially water insoluble active agent, an effective amount of non-reducing sweetener; an effective amount of water; and an effective amount of a suspending system; wherein the dye-free pharmaceutical suspension has a ... 05/04/06 - 20060093630 - Dye-free pharmaceutical suspensions and related methods A dye-free pharmaceutical suspension having a therapeutically effective amount of a first active agent consisting essentially of a first substantially water insoluble active agent, an effective amount of non-reducing sweetener; an effective amount of water; and an effective amount of a suspending system; and an effective amount of an opacifier, ... 05/04/06 - 20060093629 - Dye-free pharmaceutical suspensions and related methods A dye-free pharmaceutical suspension having a therapeutically effective amount of a first active agent consisting essentially of a first substantially water insoluble active agent having an average particle size of between about 10 and about 100 microns, an effective amount of non-reducing sweetener; an effective amount of water; and an ... 04/27/06 - 20060088558 - Vitamin e tpgs fluid concentrate comprising a low percentage of water A liquid Vitamin E TPGS concentrate composition is provided, the concentrate having a significantly higher percentage of TPGS per unit volume than traditional liquid TPGS formulations while providing the TPGS in a liquid form that can be used in softgels or mixed with water to produce desired concentrations for commercial ... 04/27/06 - 20060088557 - Novel skin care formulation Skin moisturizing formulations which can be administered in the bath or shower, depositing a thin layer of moisturizing agents on application, which is not rinsed off but remains to protect the skin from drying, resulting in smoother, softer skin feel; the formulations comprising polyvalent metal cations and fatty acids, which ... 04/27/06 - 20060088556 - Topical formulation and use of buspirone A liquid or semi-solid topical formulation of buspirone, when applied to human epidermis in vitro (following methods defined herein), results in a transepidermal flux rate of buspirone (individual or mean data) in one or more of the following ranges: 0.1 to 1.1 μg/cm2/hour as assessed over 5 hours following application; ... 04/20/06 - 20060083759 - Stabilization of the profile of release of active substances from a formulation The invention discloses a method of a physical pre-treatment of an active substance, which modifies technologically important physical properties of the active substance so as to enable the manufacture of a formulation having a more stable release profile of the active substance over the whole shelf life of the medicine ... 04/13/06 - 20060078575 - Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics A removable anti-granuloma covering made from an anti-granuloma composition including at least one anti-granuloma agent, wherein the removable anti-granuloma covering is adapted to outfit a medical device for insertion in an artificial opening in a body of a being and wherein the removable covering is adapted to contact an area ... 04/13/06 - 20060078574 - Purified phospholipid-non-steroidal anti-inflammatory drug associated compositions and methods for preparing and using same A new pharmaceutical composition is disclosed comprising a purified phospholipid-selective and/for nonselective non-steroidal, anti-inflammatory drug associated complex and methods for making and using same. A screening method for identifying compounds that form phospholipid associated complexes is also disclosed. ... 04/13/06 - 20060078573 - Methods of modifying crystal habit The invention provides methods of modifying the crystal habit of a compound without altering the crystal structure of the compound through a controlled precipitation technique in the presence of a crystal growth inhibitor as well as the crystallized compounds formed by these methods. Using these methods, the crystal habit of ... 04/06/06 - 20060073175 - Methods and formulations for delivery of pharmacologically active agents In accordance with the present invention, novel formulations have been developed which are much more effective for the delivery of hydrophobic drugs to patients in need thereof than are prior art formulations. Invention formulations are capable of delivering more drug in shorter periods of time, with reduced side effects caused ... 04/06/06 - 20060073174 - Adherent and erodible film to treat a moist surface of a body tissue A thin, flexible, bilayer or multi-layer film which when applied to a moist surface of a body tissue adheres and delivers an active agent, pharmaceutical compound, nutraceutical, flavor or other substance to the underlying surface and/or body cavity and erodes at a predetermined rate. In one application, the amount of ... 04/06/06 - 20060073173 - Large-scale manufacturing process for the production of pharmaceutical compositions Methods for manufacturing pharmaceutical compositions with a predetermined surface tension or other properties are provided. Also provided are pharmaceutical compositions with a predetermined surface tension or other properties, articles of manufacture containing the pharmaceutical compositions and systems for preparation of the compositions. ... 04/06/06 - 20060073172 - Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure The present invention provides stable ophthalmic solutions comprising a compound with serotonergic 5-HT2 receptor activity and at least one stabilizer, together with methods of using such solutions to treat glaucoma and to lower intraocular pressure. ... 03/30/06 - 20060067955 - Biocompatible polymeric systems carrying triflusal or htb New biocompatible polymeric systems carrying triflusal or HTB are described which result from the polymerization of a monomer A of the acrylic or vinylic type and carrying triflusal or HTB, wherein triflusal or HTB are linked to the remainder of the molecule of said monomer through an in vivo hydrolysable ... 03/30/06 - 20060067954 - Lipid stabilized formulations The present invention provides a lipid based system for isolating components in a pharmaceutical formulation. Also provided are methods for preparing stable pharmaceutical formulations containing at least two active ingredients. Further provided are methods of treating helminthiasis in mammals, which comprises administering a pharmaceutical composition that is highly effective against ... 03/30/06 - 20060067953 - Oral pharmaceutical formulations and methods for producing and using same Oral pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, In preferred embodiments, the pharmaceutically active compounds are ansamycins, pharmaceutically acceptable salts, or prodrugs thereof. ... 03/30/06 - 20060067952 - Low oil emulsion compositions for delivering taxoids and other insoluble drugs The present invention provides injectable oil-in-water emulsions of taxoid drugs or other water insoluble drugs. The present invention also provides methods for preparing and using such oil-in-water emulsions. ... 03/23/06 - 20060062812 - Novel compositions Compositions and method are provided, for the treatment of pain, e.g. acute breakthrough pain, by means of a systemic, non-invasive mode of administration. Specifically, the invention relates to a sublingual presentation of an opioid analgesic, such as fentanyl, or its salts, in amounts that are sufficient to treat the pain. ... 03/23/06 - 20060062811 - Medicinal cooling emulsions Coolant emulsion compositions suitable for pharmaceutical active ingredients, comprising a non-volatile cooling agent and a cellulosic polymer in an aqueous vehicle. ... 03/23/06 - 20060062810 - Microemulsion concentrate for oral administration of water-insoluble anti-cold drug and method for preparing same A microemulsion concentrate comprising a water-insoluble anti-cold drug, a surfactant and an oil, which is prepared by a method comprising: (a) dissolving the water-insoluble anti-cold drug in a co-surfactant to obtain a homogeneous drug solution; (b) adding the surfactant and the oil in the drug solution to obtain a microemulsion ... 03/23/06 - 20060062809 - Solid dispersions comprising two different polymer matrixes Present invention provides solid dispersions comprising a poorly soluble bioactive compound dispersed in a polymer matrix characterized in that the polymer matrix comprises more than one polymer. Said solid dispersions effectively stabilize the dispersed compound while stimulating the solubilisation of the compound in an aquaeous environment. ... 03/16/06 - 20060057168 - Microemulsion process and composition There is provided a process for the preparation of an oil in water (O/W) microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, the method including the steps of a) Admixing a first part including at least one of the group consisting of animal, ... 03/16/06 - 20060057167 - Stable lipophilic emulsions for acrylic coating and method of making Emulsions of lipophiles such as glycerol monostearate which are compatible with acrylic copolymer emulsions are made stable by using an emulsion stabilizer such as polysorbate 80 in an amount by weight between 1 % and 5% of the lipophile and homogenizing the emulsion wherein the emulsion micelles are less than ... 03/09/06 - 20060051381 - Cytokine antagonists for neurological and neuropsychiatric disorders Methods for treating neurological or neuropsychiatric diseases or disorders in humans by administering to the human a therapeutically effective dose of specific biologics are presented. The biologics of consideration include antagonists of tumor necrosis factor or of interleukin-1. The administration of these biologics is performed by specific methods, most, but ... 03/02/06 - 20060045891 - Density-matched suspension vehicles and pharmaceutical suspensions Density-matching is used to provide suspending vehicles, pharmaceutical suspensions, dosage forms, and kits as well as methods of making and using the vehicles, suspensions, and dosage forms. Pharmaceutical suspensions comprising a pharmaceutically active agent having an active agent density, ρA, and a suspending vehicle having a suspending vehicle density, ρSV; ... 03/02/06 - 20060045890 - Topical skin care compositions A novel combination of silicon resin, amorphous silica and low oil absorbing spherical powder is described which when added to topical skin care compositions containing high concentrations of active agents, improves their aesthetic feel and ease of application. ... 02/23/06 - 20060039933 - Method for treatment of insect bites A method of treating wounds caused by the bites of small insects or jellyfish includes applying a water-based wax emulsion to the wound. When the emulsion dries, it forms a thin, protective film over the wound. Application of the emulsion has been found to provide temporary and immediate relief of ... 02/23/06 - 20060039932 - Application of phytosteroids (and isomers thereof), folic acid, cyanocobalamine and pyridoxine in dietetic (alimentary) fibers The present invention relates to an Association of chemical agents (namely, phytosteroids (and isomers thereof), folic acids, cyanocobalamine and pyridoxine in dietetic(alimentary) fibers), with intended pharmacological action to prevent the risk of infarction and brain hemorrhage caused by the development of the atherosclerotic process and of the homocysteinemia resulting from ... 02/23/06 - 20060039931 - Stable cream preparations of phenyl-pyridone compounds for topical application The invention relates to a pharmaceutical cream preparation for topical application in the form of an oil-in-water (o/w) emulsion, containing the following constituents in the lipophilic phase: (i) an optionally substituted 1-phenyl-2-(1H)-pyridone compound or a pharmaceutically acceptable salt thereof, as an active ingredient, (ii) at least one surface-active solubilising agent ... 02/16/06 - 20060034873 - Palatable suspending vehicle for pharmaceutical ingredients The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least ... 02/16/06 - 20060034872 - Compositions and methods for preventing abuse of orally administered medications Disclosed herein is the use of chemical irritants, such as vanilloid receptor-1 agonists, in sustained/controlled release pharmaceutical preparations which also contain a drug typically having high abuse potential. Inclusion of the VR1 agonist in the pharmaceutical preparation interferes with illicit or inappropriate dosing without significantly interfering with the action of ... 02/09/06 - 20060029623 - Invert emulsions comprising at least one active agent sensitive to water and cosmetic/dermatological applications thereof Cosmetic/dermatological compositions useful for the treatment of a variety of dermatological conditions, including keratinization disorders, acne, eczema, psoriasis, etc., comprise an invert emulsion containing at least one active agent sensitive to the presence of water, notably a derivative of vitamin D, and solubilized in a glycolic or hydroglycolic dispersed hydrophilic ... 02/09/06 - 20060029622 - Water in oil emulsion comprising sterolesters The invention relates to water in oil emulsions comprising a sterol fatty acid ester to which folic acid has been added to counter act the effect of the sterol fatty acid ester on the droplet size of the dispersed aqueous phase. ... 02/02/06 - 20060024336 - Ion binding compositions The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, ... 02/02/06 - 20060024335 - Oral compositions which mask the bitter taste of a bitter-tasting agent An oral composition containing a bitter-tasting agent, such as for example, dextromethorphan, chlorhexidine, guaifenesin, pseudoephedrine, caffeine, peroxide, atorvastatin, aspirin, acetaminophen, diphenhydramine, doxylamine, sildenafil citrate, or loperamide, wherein the bitter taste ordinarily imparted by the bitter-tasting agent is abated or eliminated (i.e., masked) by an effective amount of a taste-receptor blocker, ... 01/26/06 - 20060018934 - Novel drug delivery system A novel modified release dosage form comprising of a high solubility active ingredient, which utilizes dual retard technique to effectively reduce the quantity of release controlling agents. Present invention can optionally comprise additionally another active ingredient as an immediate release form or modified release form. Present invention also relates to ... 01/26/06 - 20060018933 - Novel drug delivery system A novel modified release dosage form comprising of a high solubility active ingredient, which utilizes dual retard technique to effectively reduce the quantity of release controlling agents. Present invention can optionally comprise additionally another active ingredient as an immediate release form or modified release form. Present invention also relates to ... 01/19/06 - 20060013836 - Parenteral formulation for epothilone analogs A process for formulating certain epothilone analogs for parenteral administration is disclosed wherein the analog is dissolved in a mixture of at least 50% by volume tertiary-butanol in water, the mixture is lyophilized, the resulting lyophilized product is packaged in one vial with a sufficient amount of solvent comprising anhydrous ... 01/19/06 - 20060013835 - Controlled release bioactive agent delivery device The invention provides a controlled release bioactive agent delivery device for treatment of an eye that includes a body member having a direction of extension, a longitudinal axis along the direction of extension, and a proximal end and a distal end, wherein at least a portion of the body member ... 01/19/06 - 20060013834 - Room temperature stable aqueous liquid pharmaceutical composition A liquid pharmaceutical composition is contemplated that comprises a pharmaceutically effective amount of a drug dissolved or dispersed in an aqueous medium. The aqueous medium consists essentially of water, about 3% to about 10% w/v polyvinylpyrrolidone, about 60% to about 75% w/v of C3-C6 polyol that includes more than 55% ... 01/19/06 - 20060013833 - Thermal stabilization of biocides in matrix compositions processed at elevated temperatures A composition includes (a) a matrix, (b) a biocide, and (c) an antioxidant, in which said biocide exhibits thermal stability at matrix processing temperatures up to 250° C. ... 01/12/06 - 20060008481 - Method and composition for treating hemorrhoids A hemorrhoid-treating composition which includes a mixture of the antiseptic/bactericide/fungicide/anthelmintic gentian violet (methylrosaniline) and a lubricant such as petroleum jelly, also known as petrolatum or mineral jelly. In another embodiment, the composition is prepared as a suppository using a suitable suppository base. The composition imparts a soothing and healing effect ... 01/12/06 - 20060008480 - Compositions for delivering highly water soluble drugs The present invention provides compositions for delivering highly water-soluble drugs (such as vinca alkaloids) and methods of using such compositions. ... 01/05/06 - 20060002963 - Use of emulsions for intra and periocular injections A method for treating eye diseases by injecting intraocularly or periocularly a composition comprising an emulsion and optionally at least a pharmaceutical active ingredient. ... 12/29/05 - 20050287181 - Phospholipid gel compositions for drug delivery and methods of treating conditions using same The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of a pharmaceutically active agent and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions. One particular type of condition ... 12/29/05 - 20050287180 - Phospholipid compositions and methods for their preparation and use The present invention provides compositions that comprise a phospholipid component (that contains one or more phospholipids) and a pharmaceutically acceptable fluid carrier, where the phospholipid component is in the range from about 10% to about 90% of the total weight. Optionally, the compositions may further comprise non-phospholipid filler materials, where ... 12/29/05 - 20050287179 - Use of ethyl lactate as an excipient for pharmaceutical compositions This invention is based upon the unexpected discovery that ethyl lactate can be used as an emulsifying/dispersing excipient for numerous biologically active compounds without destroying the pharmacological activity of the active ingredient. Ethyl lactate proves to be an extremely effective agent for solubilizing biologically active compounds that are difficult to ... 12/29/05 - 20050287178 - Diagnosis and treatment of heavy gallbladder densities The present invention relates to a new clinical finding termed heavy gallbladder densities. Methods to diagnose and treat heavy gallbladder densities are disclosed. Specifically, a method of rapid patient rotation and specialized ultrasound technique using conventional equipment are described. Heavy gallbladder densities may be treated or prevented using methods traditionally ... 12/29/05 - 20050287177 - Pharmaceutical compositions A pharmaceutical composition comprising 3′-azido-3′-deoxythymidine and (2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one suitable for once daily administration ... 12/22/05 - 20050281848 - Oleaginous ointments comprising two solubilized bioactive agents for the treatment of psoriasis Topically applicable, anhydrous, hydrophobic and physically/chemically stable dermatological/pharmaceutical oleaginous ointments having effective release/penetration capacity and also having therapeutically effective amounts of calcitriol and clobetasol 17-propionate solubilized therein, are well suited for the treatment of psoriasis. ... 12/15/05 - 20050276824 - Pharmaceutical emulsions for retroviral protease inhibitors The present invention provides an emulsion formulation with high oral bioavailability containing lecithin as an emulsifier and solubilizing agent to achieve a high loading of the pyranone compound of formula I. ... 12/15/05 - 20050276823 - Methods and compositions for preventing oxidative degradation of proteins Methods and compositions for preventing oxidative damage to proteins, particularly antibodies, are provided. The compositions include a combination of metal chelators, such as DTPA, EGTA, and/or DEF, and can further include one or more free radical scavengers, particularly scavengers of oxygen radicals. Methods for enhancing protein stability using the compositions ... 12/08/05 - 20050271691 - Prepackaged aqueous pharmaceutical formulations Prepackaged aqueous pharmaceutical compositions for the treatment of a condition are disclosed including at least two different pharmacologically active agents for the treatment of the condition, a buffering agent to buffer the composition, and an osmotic-adjusting agent. Additionally, a method of forming a prepackaged aqueous pharmaceutical composition for the treatment ... 12/01/05 - 20050266033 - Generation of therapeutic microfoam Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen. ... 12/01/05 - 20050266032 - Dosage form containing multiple drugs A pharmaceutical dosage form comprising a first drug and a second drug, both of which are selected from decongestants, antitussives, expectorants, analgesics and antihistamines. The dosage form provides a plasma concentration within a therapeutic range of the second drug over a period which is coextensive with at least about 70% ... 12/01/05 - 20050266031 - Pharmaceutical suspension composition An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the suspension of one or more pharmaceutical actives that are substantially insoluble in water. The oral liquid pharmaceutical composition may further comprise pharmaceutical actives that are soluble in water and ... 11/24/05 - 20050260237 - Delivery agents for enhancing mucosal absorption of therapeutic agents A delivery agent for delivering a biologically active agent to a warm-blooded animal includes a hydrophobic moiety covalently bonded to a hydrophilic moiety. The hydrophobic moiety can include bile acids, sterols, or hydrophobic small molecules. The hydrophilic moiety can include α-amino acids, dipeptides or tripeptides, or hydrophilic small molecules. An ... 11/24/05 - 20050260236 - Direct compression polymer tablet core The present invention provides a tablet comprising a compressed tablet core which comprises at least about 80% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 80% by weight of an aliphatic amine polymer resin. The method ... 11/17/05 - 20050255131 - Clindamycin compositions and delivery system therefor Clindamycin compositions contain water and a co-solvent and optionally an emulsifier. ... 11/17/05 - 20050255130 - Retinoid solutions and formulations made therefrom Compositions for topical application for treating a skin disorder (e.g., acne) include a retinoid, which is solubilized completely in alcohol only with the aid of cosolvents such as esters (e.g., alkyl benzoate, isopropyl palmitate, isopropyl myristate, diisopropyl adipate and their derivatives). This completely solubilized retinoid can be used to formulate ... 11/10/05 - 20050249757 - Pharmaceutical cream formulations A pharmaceutical cream composition is provided comprising (a) a therapeutically effective amount of one or more active pharmaceutical ingredients comprising one or more macrolide related immunosuppressants or pharmaceutically acceptable salts or esters thereof; (b) one or more cream forming agents; and (c) an effective amount of one or more skin ... 11/03/05 - 20050244439 - Composition comprising anionic clay layered host material with intercalated functional-active organic compound A composition comprising particles of an anionic clay layered host material and functional-active organic compound dispersed in an aqueous medium is described, wherein at least 80% of the finctional-active organic compound in the dispersion is intercalated between layers of the layered host material particles, and the stoichiometric ratio of anionic ... 11/03/05 - 20050244438 - Simple and multiple emulsions for decontamination of an organism or surfaces The present invention relates to the use of simple or multiple emulsions comprising in their organic phase one or more extractant compounds capable, when said emulsions are brought into contact with an external medium, either biological such as gastric liquid, skin or blood, or artificial such as metal or plastic ... 10/27/05 - 20050238675 - Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications Aqueous liquid or gel formulations of fat soluble vitamins, essential nutrients and other pharmaceutical agents have enhanced concentration of the active components relative to known compositions and therefore have enhanced bioavailability. The aqueous solutions or gels form a free flowing powder when they are absorbed on a suitable pharmaceutically acceptable ... 10/27/05 - 20050238674 - Stable injectable compositions This invention relates to a stable parenteral aqueous solutions comprising either (a) diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or (b) an inclusion complex of diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or a mixture of (a) and (b), which are suitable for intramuscular ... 10/27/05 - 20050238673 - Methods of enhancing solubility of compounds This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions. ... 10/27/05 - 20050238672 - Antifungal drug delivery An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be ... 10/20/05 - 20050232954 - Porous substances and methods for producing the same A physiologically active porous substance of the present invention obtained by treating a physiologically active solid substance with a carbon dioxide in a supercritical or subcritical state or a liquid carbon dioxide has a significantly improved dissolution rate and can easily be handled. ... 10/20/05 - 20050232953 - Microemulsions having a binary phase differentiability and active substance differentiability, the production thereof and their use, particularly for the topical supply of oxygen Micro-emulsions having a binary phase differentiability and active substance differentiability, the production thereof, and their use, particularly for the topical supply of oxygen The present invention relates to skin-compatible micro-emulsions that are suitable for the treatment of hair and skin, based on a primary W/O micro-emulsions that are converted into ... 10/20/05 - 20050232952 - Self emulsifying drug delivery systems for poorly soluble drugs A pharmaceutical composition in a form of a self-microemulsifying drug delivery system comprising: one or more therapeutic agent(s) which have low solubility in water or are water-insoluble, vitamin E, one co-solvent selected from propylene glycol and ethanol, one or more bile salts, TPGS, and one further surfactant selected from Tyloxapol ... 10/13/05 - 20050226898 - Compositions and methods for transdermal oxybutynin therapy The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy. In one aspect, these compositions and methods provide a lower plasma concentration of oxybutynin metabolites, such as N-desethyloxybutynin, which is presumed to be contributing at ... 10/06/05 - 20050220825 - Molecular dispersions of drospirenone Described are pharmaceutical compositions comprising at least one steroidal drug such as a progestin (e.g. drospirenone, progesterone, eplerenone, etonogestrel) and/or an estrogen (estradiol and esters thereof) in molecularly dispersed form. The composition comprises a steroidal drug, preferably drospirenone, which is present in the composition in a non-particulate form. Preferably, the ... 10/06/05 - 20050220824 - Powder compaction and enrobing Powder, e.g. of a medicament, is compacted and enrobed to produce compacted powder slugs by preferably mechanically compacting a powder and forming a film of material, preferably hydroxy propyl methyl cellulose, by vacuum or pressure differential, about the surface of the powder thus compacted. ... 10/06/05 - 20050220823 - Ophthalmic composition comprising ascomycin This invention relates to topical ophthalmic compositions comprising an ascomycin e.g. for the treatment of inflammatory diseases such as blepharitis. ... 09/29/05 - 20050214331 - Pharmaceutical compositions for bioactive peptide agents Disclosed are pharmaceutical compositions suitable for oral administration of bioactive peptides. Particularly, the pharmaceutical compositions comprise peptides formulated as suspensions stabilized with a dispersing agent. The compositions may be encapsulated in capsules for oral administration. The compositions show improved dissolution characteristics, which are believed to make them suitable for use ... 09/29/05 - 20050214330 - Process for producing sustained-release composition A process for producing a sustained-release composition which comprises mixing an aqueous solution containing a physiologically active substance and an acid or base in a molar amount of 1.5 or more times that of the physiologically active substance with a solution of a biodegradable polymer and then drying the mixture ... 09/22/05 - 20050208083 - Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided. ... 09/22/05 - 20050208082 - Aqueous emulsions of lipophile solubilized with vitamin e tpgs and linoleic acid Disclosed herein is an aqueous emulsion. The lipid phase of the emulsion includes a blend of a therapeutically effective concentration of a lipophile, a concentration of Vitamin E TPGS, and a concentration of linoleic acid. The presence of linoleic acid increases the solubilizing affect of Vitamin E TPGS on the ... 09/22/05 - 20050208081 - Use of moxaverin for treating erectile dysfunction, forms of dementia or diseases associated to an arteriosclerotic occlusion The invention relates to a drug containing an aqueous formulation of Moxaverin and at least one water-miscible solubilizer. ... 09/22/05 - 20050208080 - Formulation for the administration of medicinal substances A formulation for administration of a medicinal substance, comprises a sandwich biscuit having two or more biscuit layers that support filler layer(s), in which the filler layer comprises a dosage unit form, or a multiple or sub-multiple thereof, of a medicament that is unpalatable in having, for example, a gritty ... 09/15/05 - 20050202053 - Liquid pharmaceutical composition This invention relates to new pharmaceutical compositions and methods for their preparation, and in particular it relates to taste-masked liquid compositions comprising a solution of a histamine H2-antagonist complexed with an alginate and also containing a humectant. The solution is buffered to a pH of between about 6 to 7. ... 09/15/05 - 20050202052 - Flavored medicaments to deter or attract and kill microorganisms Any orally, injected or topically administered medicament is prepared into a dosage form that is flavored to the pallet of the offending and targeted bacteria or microbe, thereby using the innate flavor preferences of bacteria/microbes to attract them to the pharmaceutical active principle which eradicates them more effectively than non-flavor ... 09/15/05 - 20050202051 - Pharmaceutical vehicle A pharmaceutical solution is capable of being ejected from a thermal fluid ejection device onto a substrate. The solution includes a vehicle with predetermined properties, and an active pharmaceutical ingredient with a solubility of at least about 30 mg/ml in the vehicle. The vehicle substantially evaporates from the substrate. ... 09/15/05 - 20050202050 - Single tank process for preparing tannate liquid and semi-solid dosage forms A manufacturing process for tannate salt complexes of pharmaceutically active compounds includes the steps of dissolving a salt or free base of an active pharmaceutical ingredient in a pharmaceutically acceptable liquid in the presence of a dispersing agent and tannic acid to form a dispersion and combining the tannate salt ... 09/15/05 - 20050202049 - Retinoid-containing preparations Preparations comprising at least one retinoid, at least one water-soluble antioxidant and at least one oil-soluble antioxidant, where, per part by weight of retinoid, at least 1 part by weight of one or more water-soluble antioxidants and 0.1 to 100 parts by weight of one or more oil-soluble antioxidants are ... 09/08/05 - 20050196417 - Liquid pharmaceutical composition This invention relates to new pharmaceutical compositions and methods for their preparation, and in particular it relates to taste-masked liquid compositions comprising a solution of a histamine H2-antagonist complexed with an alginate and also containing a humectant. The solution is buffered to a pH of between about 6 to 7. ... 09/08/05 - 20050196416 - Dispersions prepared by use of self-stabilizing agents The present invention relates to a dispersion of an active agent, which includes a multiphase system of an organic phase and an aqueous phase. The agent, preferably poorly water soluble, possesses surface active properties and itself serves as a dispersant or a stabilizer for the dispersion. The dispersion is suitable ... 09/01/05 - 20050191325 - Cushioning wax beads for making solid shaped articles Biologically inactive cushioning beads comprise at least one compressible cushioning component consisting essentially of a microcrystalline hydrocarbon wax or a natural wax, the said wax being at least 30% by weight of the biologically inactive cushioning beads. Such beads are useful for making solid shaped articles containing biologically active ingredients ... 09/01/05 - 20050191324 - Flavoring systems for pharmaceutical compositions and methods of making such compositions A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium ... 09/01/05 - 20050191323 - Pharmaceutical formulations comprising paclitaxel, derivatives and pharmaceutically acceptable salts thereof The invention concerns paclitaxel solubilizers and formulations thereof with a high propensity to dissolve paclitaxel. The formulations of the invention reduce or obviate the need for the disadvantageous excipient Cremophor® EL. The formulations of the invention are useful for administering paclitaxel, its derivatives, or pharmaceutically acceptable salts of such derivatives ... 09/01/05 - 20050191322 - Compositions for preventing posterior capsular opacification and the use thereof The present invention relates to a composition comprising a sterile ophthalmic composition, which comprises one or more agents capable of inhibiting lens epithelial proliferation dissolved in a physiologically isotonic solution. The present invention also relates to a method of preventing capsular opacification comprising by using said composition. The method comprises ... 08/25/05 - 20050186230 - Elemene compositions containing liquid oil The present invention provides injectable water-in-oil emulsions that comprise elemenes (preferably, bete-elemene), liquid oil, an emulsifier (optionally) and a pharmaceutically acceptable aqueous phase. The present invention also provides methods for making and using such emulsions. ... 08/25/05 - 20050186229 - Pleasant-tasting aqueous liquid composition of prednisolone sodium phosphate A liquid pharmaceutical composition is contemplated that comprises a pharmaceutically effective amount of prednisolone sodium phosphate (PSP) dissolved or dispersed in an aqueous medium that is free of ethanol. The aqueous medium consists essentially of water, about 3 to about 10 weight percent polyvinylpyrrolidone, about 60 to about 75 weight ... 08/18/05 - 20050180998 - Systems and methods for freezing, mixing and thawing biopharmaceutical material A system for controlled freezing, storing and thawing of a biopharmaceutical material includes a cavity for receiving a container for holding the biopharmaceutical material. Further included are at least a pair of opposed surfaces facing the biopharmaceutical material holding container. At least one of the opposed surfaces includes a moveable ... 08/18/05 - 20050180997 - Drug delivery system A combination product comprising a positive oil in water emulsion wherein said emulsion comprises a compound presenting free NH2 groups, at its natural state, at the oil-water interface, and an antibody, wherein said compound is linked to said antibody by a heterobifunctional linker, linking said NH2 groups to SH groups ... 08/11/05 - 20050175642 - Stable loratadine spill resistant formulation The present invention provides for a storage stable pharmaceutical liquid suspension for oral administration having a pharmaceutically effective amount of an antihistamine. The storage stable suspension preferably contains loratadine. The present invention further provides a process of preparing the storage stable pharmaceutical liquid suspension as well as a method of ... 08/11/05 - 20050175641 - Percutaneous and perungual delivery system The invention relates to a substantially homogeneous liquid composition capable of percutaneous delivery of one or more physiologically active agents, the composition including at least one physiologically active agent, a volatile solvent, and a rate modulating carrier comprising a hydrophilic polymer and a hydrophobic polymer the combination of the hydrophilic ... 08/11/05 - 20050175640 - External medicine for treating dermatitis An external medicine for treating dermatitis wherein an adrenocortical steroid is included by a cyclodextrin; and 0.025 to 0.5% by weight of the adrenocortical steroid, 0.2 to 30% by weight of the cyclodextrin, and 0.5 to 55% by weight of dextran or pullulan are dissolved in an aqueous solution containing ... 08/11/05 - 20050175639 - Methods The molecules of formula (I) are useful in treating diabetes, obesity, hypercholesterolaemia, hyperlipidaemia, cancer, inflammation or other conditions in which modulation of lipid or eicosanoid status or functions may be desirable. Formula (I): Z1-X-Z2 wherein a) Z1 represents CO2H or a derivative thereof; b) Z2 represents F, H, —CO2H or ... 08/04/05 - 20050169945 - Composition for protecting keratin material, process of making, uses thereof The present invention relates to a process for preparing a (cosmetic) composition useful for example for the treatment of keratin materials, in particular the skin and human keratin fibres such as the hair, to the compositions produced, and also to a process for treating keratin materials using this composition. The ... 07/28/05 - 20050163812 - Simulated vernix compositions for skin cleansing and other applications A composition and a method of producing a composition which simulates hydration, cleansing and other properties of native vernix. The composition contains, in one embodiment, hydrated synthetic cells in a lipid matrix to provide properties which are substantially similar to those of native vernix, and may also contain proteins. In ... 07/28/05 - 20050163811 - Topical solutions comprising high concentrations of piperidinopyrimidine derivatives and methods of use thereof This invention relates to a method for achieving a novel solution comprising a high percentage of a piperidinopyrimidine derivative, more particularly minoxidil. The method of the current invention results in a highly effective solution for facilitating hair growth comprising a high concentration of Minoxidil, that is not cosmetically unattractive when ... 07/21/05 - 20050158348 - Vehicle for topical delivery of anti-inflammatory compounds A vehicle for topical application which contains a liquid eutectic mixture of hydrophobic compounds to improve solubility of pharmaceutically active component and enhance topical and transdermal delivery. ... 07/14/05 - 20050152928 - Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant The use of a composition of one or more aminoalcohol buffers in combination with one or more antimicrobial agents to disinfect contact lenses and preserve ophthalmic lens compositions is described. Ophthalmic lens solutions containing compositions of one or more aminoalcohol buffers in combination with one or more antimicrobial agents and ... 07/07/05 - 20050147629 - Pharmaceutical formulation comprising non-peptide renin inhibitor and surfactant Composition comprising (1) a non-peptide renin inhibitor which is poorly soluble to readily soluble in water and (2) at least one physiologically tolerated anionic surfactant, at least one physiologically tolerated amphoteric surfactant at least one physiologically tolerated neutral surfactant, or a mixture of at least two of these surfactants, with ... 06/30/05 - 20050142152 - Polymeric materials, their preparation and use Disclosed are highly resilient and cohesive gels formed by the cross-linking of hyaluronan or hylan, their salts or derivatives thereof, using divinyl sulfone (DVS) as the cross-linking agent. Also disclosed are viscoelastic fluids containing alkylsulfone groups covalently attached to the backbone of the polymer, formed by the mono-functionalization of the ... 06/16/05 - 20050129720 - Hydrogel thin film containing extracellular matrix components The thin film of the invention comprises a hydrate of a vitrified gel containing one or more extracellular matrix components, which can be integrated with a retainer as required. A hydrogel thin film containing one or more extracellular matrix components such as thin-film collagen hydrogel thin film, which is useful ... 06/16/05 - 20050129719 - Concentrated emulsion formulation for silatecan The present application relates to a concentrated emulsion formulation for water-insoluble silatecan comprising silatecan of 0.01-1.0% (W/W), phospholipid of 4.79-75% (W/W); propylene glycol of 24.79˜95% (W/W); optional ethanol of 0.1-40% (W/W); optional surfactant of 0.1-10% (W/W), especially Tween® 80. The present application also relates to a method for manufacturing the ... 06/16/05 - 20050129718 - Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant Pharmaceutical compositions, which enable high absorption when administered orally, and which comprise a cyclosporin or cyclosporin derivative dissolved in a solvent-surfactant system further comprising a hydrophilic surfactant and a lipophilic surfactant, with minimal quantities of solvents. ... 06/02/05 - 20050118206 - Surfactant-based gel as an injectable, sustained drug delivery vehicle The present invention provides methods and compositions for the sustained delivery of beneficial agents. In certain embodiments, the invention provides compositions comprising a surfactant, a solvent, and a beneficial agent, wherein upon exposure to a hydrophilic environment, the surfactant and solvent form a viscous gel and the beneficial agent is ... 06/02/05 - 20050118205 - Taste masked liquid pharmaceutical compositions This invention is directed to a taste masked liquid pharmaceutical composition comprising a pharmaceutically active agent and a taste masking composition. In particular, the taste masking composition comprises a taste masking effective amount of an artificial sweetener. ... 06/02/05 - 20050118204 - Methods for controlling membrane permeability of a membrane permeable substance and screening methods for a membrane permeable substance The present invention relates to a method for controlling membrane permeability of a membrane permeable substance, and more particularly it relates to a method for controlling membrane permeability of a membrane permeable substance by changing the curvature of the membrane. The invention also relates to a screening method for a ... 06/02/05 - 20050118203 - Mixing powder of plant sterol and emulsifier, and method for preparing the same Disclosed are a mixing powder of plant sterol and emulsifier, and method for preparing the same. More particularly, the present invention provides a mixing powder of plant sterol and emulsifier for application to almost all food, irrespective of food base, to obtain an improvement in the dispersion stability of the ... 06/02/05 - 20050118202 - Solid compositions containing compounds unstable to oxygen and method for stabilization thereof The present invention aims at stabilizing a solid composition containing a nitrogenous fused-heterocycle compound unstable to oxygen to provide a stable pharmaceutical preparation. The stabilization can be attained by keeping the equilibrium moisture content at 10% or above and/or adding ascorbic acid or a salt thereof, by preliminarily applying a ... ### FreshPatents.com Support |