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Drug, Bio-affecting And Body Treating Compositions > Immunoglobulin, Antiserum, Antibody, Or Antibody Fragment, Except Conjugate Or Complex Of The Same With Nonimmunoglobulin Material > Extracorporeal Or Ex Vivo Removal Of Antibodies Or Immune Complexes (e.g., Removal Of Autoantibodies, Etc.); Or Extracorporeal Or Ex Vivo Removal Of Antigen By Antibodies (e.g., Removal Of Cancer Cells From Bone Marrow By Antibodies, Etc.) Extracorporeal Or Ex Vivo Removal Of Antibodies Or Immune Complexes (e.g., Removal Of Autoantibodies, Etc.); Or Extracorporeal Or Ex Vivo Removal Of Antigen By Antibodies (e.g., Removal Of Cancer Cells From Bone Marrow By Antibodies, Etc.)Extracorporeal Or Ex Vivo Removal Of Antibodies Or Immune Complexes (e.g., Removal Of Autoantibodies, Etc.); Or Extracorporeal Or Ex Vivo Removal Of Antigen By Antibodies (e.g., Removal Of Cancer Cells From Bone Marrow By Antibodies, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.08/16/07 - 20070190050 - Apparatus and method for down-regulating immune system mediators in blood A method and apparatus for preventing and treating septicemia in patient blood is provided. The extracorporeal system includes an antimicrobial device to inactivate at least 99% of bloodborne microorganisms, a hemoconcentrator/filtration unit to remove approximately 50-75% of target molecules from the patient blood and a filter unit to remove target ... 08/02/07 - 20070178085 - Bont/a peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides. ... 08/02/07 - 20070178084 - Continuous flow chamber device for separation, concentration, and/or purfication of cells The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive ... 07/12/07 - 20070160599 - Thimerosal removal device A device for the removal of heavy metals and heavy metal complexes, such as thimerosal, from medications is provided wherein the device comprises a dosing device or a solid support having at least one substantially purified metallothionein protein associated therewith. Additionally, methods to remove thimerosal from medications are provided. ... 06/21/07 - 20070141050 - Methods of depleting antibodies directed towards major histocompatibility complex The invention provides a method of depleting anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and removing at least the recombinant MHC molecules to which antibodies to said recombinant MHC molecules contained within the ... 04/26/07 - 20070092509 - Method for ex-vivo separation of apoptotic chromatin fragments from blood or plasma for prevention and treatment of diverse human diseases A method of prevention/treatment of pathological consequences of DNA damage triggered by incorporation of circulating apoptotic chromatin fragments into healthy cells of individuals/patients in need therefore, said method comprising ex vivo or extra corporeal treatment of blood/plasma for removal of circulating chromatin fragments released from apoptotic cells which apoptotic chromatin ... 04/26/07 - 20070092508 - Detoxification depot for alzheimer's disease The invention is directed to a device that is placed inside an Alzheimer's disease (AD) patient for the purpose of extracting and accumulating neurotoxic beta-amyloid peptides (nt-bAP) from body fluids. AD is the consequence of a process in which nt-bAP aggregates to form fibrils and plaques which can cause nerve ... 04/19/07 - 20070086996 - Biodegradable t-cell activation device and methods A biodegradable device for activating T-cells includes a biodegradable support and a binder attached to the biodegradable support, the binder having reactivity to one or more agents capable of binding to a T-cell surface antigen. ... 09/21/06 - 20060210558 - Hematopoietic cell selectin ligand polypeptides and methods of use thereof The invention feature methods and compositions for treating inflammatory disorders, hematopoietic disorders and non-hematopoietic disorders (e.g., non-hematopoietic cancers) and for isolating cells (e.g., stem cells) in a mammal. ... 09/14/06 - 20060204495 - Isolation and identification of cross-reactive t cells Cross-reactive T cells recognizing both MBP93-105 and HHV-61-13 peptides represent a significant subset of T cells with some degree of TCR degeneracy. It appears that the recognition of the cross-reactive T cells has a less stringent requirement for the flanking residues of the two peptides. In contrast, these flanking residues ... 07/20/06 - 20060159680 - Targeted apherisis for the treatment of rheumatoid arthritis This invention uses “targeted apheresis” to treat rheumatoid arthritis patients. “Targeted Apheresis” is a process whereby the RF and immune complexes responsible for causing the disease symptoms are selectively removed from the blood by passing the blood through a cartridge containing immobilized IgG. The RF and immune complexes are bound ... 06/22/06 - 20060134108 - Method for retarding or precluding alzheimer's dementia A method for treating a condition related to the development of Alzheimer's disease (AD) is disclosed. The method involves the removal of circulating autoantibodies of a biochemical marker or markers, specifically human glial fibrillary acidic protein (GFAP) and glyceraldehyde-3-phosphate-dehydrogenase (GAPDH), from the sera of a patient in an amount effective ... 06/08/06 - 20060121027 - Method for detecting and isolating t lymphocytes that recognize a defined antigen What is suggested herein is the use of CD154 for the detection and/or isolation of antigen-specific T lymphocytes and a method for the detection and/or isolation of antigen-specific T lymphocytes, wherein the suspension is contacted with a CD40/CD154 system inhibitor, intra- or extracellular determination of CD154 is effected, and the ... 03/16/06 - 20060057142 - Biocompatible devices, systems, and methods for reducing levels of pro-inflammatory or anti-inflammatory stimulators or mediators in the blood Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce ... 02/16/06 - 20060034837 - Method and agents for the prevention, inhibition and therapy of cancers Disclosed are uses of Gangliosides GM1 and/or asialo-GM1 substances simulating the carbohydrate portion of said gangliosides with regard to bonding to anti-GM1 antibodies and/or anti-ADM1 antibodies for producing agents which bind or block anti-GM1 antibodies and/or anti-AGM1 antibodies which bond to natural killer cells (NKC) or for blocking antigen-presenting cells ... 02/02/06 - 20060024301 - Prostate-specific polypeptides and fusion polypeptides thereof Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a ... 12/22/05 - 20050281809 - Plasma detoxification and volume control system and methods of use An extracorporeal circuit for removing toxins from the blood and plasma volume control in patients suffering from sepsis and renal failure. The extracorporeal circuit disclosed herein comprises a plasma filter, a toxin removal device and optionally a hemofilter that minimizes electrolyte and protein depletion from the treated plasma while effectively ... 12/08/05 - 20050271653 - Methods and devices for targeting a site in a mammal and for removing species from a mammal Methods and devices for improved targeting to a site in an organism, particularly to a tumor target site and for extracorporeal affinity adsorption, particularly in the treatment of cancer, atherosclerosis, including coronary artery disease, unstable angina, other acute ischemic syndromes and idiopathic dilated cardiac myopathy. In one aspect of the ... 11/17/05 - 20050255099 - Antigenic fusion protein carrying galalpha 1,3gal epitopes The present invention relates to an antigenic fusionprotein, which carries multiple Galα1,3Gal epitopes. The fusion protein according to the invention may also be comprised of a heavily glycosylated mucin part, which mediates binding to selecting, such as PSGL-1, and a part, which exhibits immunoglobulin properties, such as the Fc part ... 11/10/05 - 20050249724 - Extracorporeal stablised expanded bed adsorption method for the treatment of sepsis The present invention provides an extracorporeal adsorption method for removing harmful substances from blood in a way that is practicable in everyday clinical practice and applicable for the timely intervention to present the development of sepsis. Said extracorporeal adsorption method being effected by an adsorption column assembly where the adsorption ... 10/27/05 - 20050238641 - Endotoxin-binding ligands and their use An affinity ligand-matrix conjugate of the structure Z-Spacer-[NX-A]m-NY-A-NK2 is useful for the isolation, separation, purification, characterization, identification or quantification of endotoxins in an aqueous system, wherein m is an integer of at least one; each A independently represents an optionally substituted linear, branched or cyclic saturated hydrocarbon chain containing 1 ... 09/01/05 - 20050191291 - Methods for preparing t-cells for cell therapy T-cells are generated with enhanced immunostimulatory capabilities for use in self therapy treatment protocols, by utilizing a biodegradable device with a biodegradable support that has one or more agents that are reactive to T-cell surface moieties. The biodegradable devices are mixed with the T-cells sufficiently so that the one or ... 08/11/05 - 20050175604 - Treatment of autoimmune diseases, including aids The present disclosure concerns the treatment of a patient with autoimmune disease, including AIDS, by neutralizing, removing or inhibiting different types of interferons, tumor necrosis factor, HLA class II antigens, IgE, and other pathological factors and/or their receptors, as well as neutralizing, removing or inhibiting autoantibodies, including antibodies to target ... 07/21/05 - 20050158306 - Treatment for neuro-degenerative disease by a blood cleansing system using monoclonal antibodies Neuro-degenerative diseases such as Alzheimer's Disease with circulating molecules that pass through the Blood Brain Barrier which can generate a monoclonal antibodies specific to the offending circulating molecules are treated with an external blood cleansing system utilizing the monoclonal antibodies to extract the offending molecules. ... ### FreshPatents.com Support |