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Drug, Bio-affecting And Body Treating Compositions > Whole Live Micro-organism, Cell, Or Virus Containing > Animal Or Plant Cell Animal Or Plant CellAnimal Or Plant Cell patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.08/16/07 - 20070190038 - Closed cell culture system An object of the present invention is to provide a tissue cell culture system whereby a call tissue can be efficiently and quickly proliferated in vivo and the onset bacterial infection in an injured part can be avoided in the course of a treatment. More specifically, a closed cell culture ... 08/16/07 - 20070190037 - Artificial vascular grafts, their construction and use The present relates to artificial vascular grafts, methods for manufacturing and uses for them. The grafts comprise an inner surface on which cells genetically altered to express or over-express one or more cell adhesion factors or one or more cell adhesion factors and one or more cell proliferation growth factors ... 08/16/07 - 20070190036 - Microencapsulation of pancreatic islets within a thin coat of glucagon-like peptide-1 functionalized poly(ethylene glycol) Microencapsulation of pancreatic islets within a thin poly(ethylene glycol) (PEG) coat is provided. The PEG coat is functionalized with an insulinotropic agent, glucagon-like peptide 1 (GLP-1). The encapsulated pancreatic islets may be used for the treatment of type I diabetes. ... 08/16/07 - 20070190035 - Diabetes treatment methods and drug targets therefor Provided are methods of treating insulin resistance or type II diabetes. Disrupting CAP in the macrophage can alter the inflammatory response associated with impaired insulin action and ultimately result in improved insulin action in target tissues. One aspect of the invention involves administering a CAP antagonist to a patient afflicted ... 08/16/07 - 20070190034 - Immunomodulation using placental stem cells The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations. ... 08/09/07 - 20070184035 - Artificial stabilized composition of calcium phosphate phases particularly adapted for supporting bone cell activity This invention relates to a bioactive artificial sintered composition for providing a morphology capable of consistently supporting bone cell activity thereon. The composition comprises stabilized calcium phosphate phases developed by the conversion of a hydroxyapatite substance in the presence of stabilizing entities at sintering temperatures into insolubilized and stabilized tricalcium ... 08/09/07 - 20070184034 - Combination pressure therapy for treatment of hypertension, blood production, and stem cell therapy Methods for administering pressure changes to a user for the treatment and prevention of diseases and conditions are disclosed herein. Methods of administering Cyclic Variations in Altitude Conditioning Sessions (CVAC Session(s)) for the treatment of hypertension, blood production, and stem cell therapy are disclosed herein. ... 08/09/07 - 20070184032 - Tissue harvesting device and method A tissue harvesting method and device for obtaining micrograft tissue particles within the size range of 50-1500 microns, and more preferably 500-1000 microns, and most preferably 600 microns. The particles may be processed after a piece of donor tissue has been excised from the donor site, or processed into the ... 08/09/07 - 20070184031 - Uses of bispecific antibody coated dendritic cells pulsed with antigens and gm-csf in immune regulation GM-CSF administered before immunization exerted a sustained suppressive effect against the induction of myasthenia gravis (MG). This suppression was associated with lowered serum autoantibody levels, reduced T cell proliferative responses to AChR, and an expansion in the population of FoxP3+ regulatory T cells. Manipulating DCs to expand regulatory T cells ... 08/09/07 - 20070184030 - Large scale storage of viable somatic stem and/or progenitor cells A large scale storage system of viable somatic stem and/or progenitor cells for use in a method of treatment of a disease or a disorder of a patient is described. The storage system includes a large number of solid supports having cryopreserved/frozen viable somatic stem and/or progenitor cells from patients, ... 08/09/07 - 20070184029 - Method of treating cancer using platelet releasate Platelets are concentrated from the blood of a patient. The platelets are treated by a method such as ultrasound or agitation to obtain platelet releasate. This releasate as a whole or a component thereof is formulated into an injectable formulation which is administered to the same patient the platelets were ... 08/02/07 - 20070178074 - Chondrocyte culture formulations The present invention provides methods and compositions for providing graft recipients with chondrocytes. Specifically, the methods and compositions of the invention provide for populations of chondrocytes that may be isolated from a patient and cultured in vitro to generate a proliferating population of chondrocytes that exhibit great proliferation capacity. The ... 08/02/07 - 20070178072 - Method for inducing differentiation of regulatory t cells usinggip-anchored protein agonist and pharmaceutical composition therefor ( as amended An object of the present invention is to provide a method for inducing the differentiation of and/or promoting the proliferation of regulatory T cells, an immunosuppressive method using these methods, and pharmaceutical compositions for use in these methods. Furthermore, a method for inducing the differentiation of and/or promoting the proliferation ... 08/02/07 - 20070178071 - Stem-cell, precursor cell, or target cell-based treatment of multiorgan failure and renal dysfunction Methods for the treatment of acute renal failure, multi-organ failure, early dysfunction of kidney transplant, chronic renal failure, organ dysfunction, and wound healing are provided. The methods include delivering a therapeutic amount of hematopoietic stem cells, non-hematopoietic, mesenchymal stem cells, hemangioblasts, and pre-differentiated cells to a patient in need thereof. ... 07/26/07 - 20070172465 - Use of umbilical cord blood stem cells to treat ischemic event The invention relates generally to methods for isolation and culture of umbilical cord blood stem cells, cells isolated by the methods, and therapeutic uses for those cells. ... 07/26/07 - 20070172464 - Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same The present invention relates to stem cells which exhibit increased sensitivity to a chemoattractant and, more particularly, to methods of generating and using them such as in clinical applications involving stem cell transplantation. ... 07/19/07 - 20070166290 - Lineage restricted glial precursors from the central nervous system A glial precursor cell population from mammalian central nervous system has been isolated. These A2B5+ E-NCAM− glial-restricted precursor (GRP) cells are capable of differentiating into oligodendrocytes, A2B5+ process-bearing astrocytes, and A2B5− fibroblast-like astrocytes, but not into neurons. GRP cells can be maintained by regeneration in culture. GRP cells differ from ... 07/19/07 - 20070166289 - Autologous human dna grafting - anti- & reverse aging process, method Anti-aging process and method for delivering younger human DNA to tissues, through the periodic infusion (auto-transfusion) of previously harvested autologous younger stem cells, resulting in re-establishment of an earlier relative biological clock set-point, with respect to the number of cell generations-divisions. ... 07/19/07 - 20070166288 - Formulation to improve survival of transplanted cells The survival of cells during transplantation is enhanced. Cells to be transplanted are administered in a formulation that provides two ore more survival enhancing factors. Optionally, prior to administration, the cells are cultured in the presence of factors that enhance survival, and may be heat shocked prior to transplantation. ... 07/12/07 - 20070160584 - Method of bone regeneration It is an object of the present invention to provide a method for effectively regenerating bone, and more specifically to provide a method for regenerating bone that is capable of treating patients suffering from bone defect or bone injury. The present invention provides a method for regenerating bone, which comprises ... 07/12/07 - 20070160583 - Method for purifying mesenchymal stem cells The invention relates to a method for purifying mesenchymal stem cells, producing cells corresponding to prior art, the cells obtained being characterised by an increased proliferation capacity while maintaining the multipotency and typical antigen characteristics. To this end, mesenchymal stem cells that can be multiplied in a significantly improved manner ... 07/12/07 - 20070160582 - Apparatus and methods for amplification of blood stem cell numbers The present invention provides an apparatus and methods for expansion of hematopoietic stem cell numbers. The stem cells are cultured and differentiated cells and endogenous growth factors are removed (depleted), permitting long term culture and expansion of the stem cells. The hematopoietic stem cells are used in numerous therapeutic procedures. ... 07/05/07 - 20070154463 - Stem cell originated from salivary gland duct epithelium and use of the same A stem cell which can be differentiated to a hepatic cell, a pancreas cell or to a salivary gland cell is disclosed. The stem cell according to the present invention is originated from salivary gland duct epithelium, which can be differentiated to an alpha-fetoprotein-positive cell, an albumin-positive cell, an amylase-positive ... 07/05/07 - 20070154462 - Augmentation and repair of tissue defects with in vitro cultured fibroblasts Certain embodiments here in are directed to a method of treating a tissue associated with a defect in a human including wrinkles, rhytids, depressed scar, cutaneous depressions, stretch marks, hyperplasia of the lip, nasolabial fold, melolabial fold, scarring from acne vulgaris, and post-rhinoplasty irregularity. The tissue defect may be treated ... 07/05/07 - 20070154461 - Tissue treatments with adipocyte cells Certain embodiments here in are directed to a method of treating a tissue associated with a defect in a human including wrinkles, rhytids, depressed scar, cutaneous depressions, stretch marks, hyperplasia of the lip, nasolabial fold, melolabial fold, scarring from acne vulgaris, and post-rhinoplasty irregularity. The tissue defect may be treated ... 07/05/07 - 20070154460 - Device and method for rapid aspiration and collection of body tissue from within an enclosed body space Device and method for rapid extraction of body tissue from an enclosed body cavity. Hollow entry cannula with optional core element provides entry into body tissue space such as bone marrow. Aspiration cannula is inserted through cannula into body tissue and is manipulated to advance directionally through body cavity. Optional ... 06/28/07 - 20070148143 - Human cytokine receptor Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.” ... 06/28/07 - 20070148142 - Pharmaceutical composition for treatment of wounds containing blood plasma or serum The present invention relates to a pharmaceutical composition for the treatment of wounds containing blood plasma or serum and a method for treating wounds effectively by applying said composition to the wound site to normalize the tissue-environment around the site. ... 06/28/07 - 20070148141 - Method of using hepatic progenitors in treating liver dysfunction Methods of using hepatic progenitors in treating liver dysfunction are provided. More particularly, methods of using hepatic progenitor cells, including hepatic stem cells, in treating liver dysfunction in the absence of immune-suppressing amounts of an immunosuppressant. ... 06/28/07 - 20070148140 - Compositions and methods to enhance viability and function of islet cells This invention uses placental alkaline phosphatase (“PALP”), and other members of the alkaline phosphatase family, to reduce the death and thereby maintain or enhance the viability and function of insulin-producing islet β-cells including insulin secretion. PALP may be administered to a patient that has received transplanted islet cells to protect ... 06/28/07 - 20070148139 - Fabrication of vascularized tissue using microfabricated two-dimensional molds A method and materials to create complex vascularized living tissue in three dimensions from a two-dimension microfabricated mold has been developed. The method involved creating a two dimensional surface having a branching structure etched into the surface. The pattern begins with one or more large channels which serially branch into ... 06/28/07 - 20070148138 - Hair follicle graft from tissue engineered skin The present invention provides a hair graft comprising (a) tissue engineered skin comprising a tissue engineered epidermal layer, a tissue engineered dermal layer, and hair follicle progenitor cells and (b) a scaffold. The invention also provides methods of making and using the hair grafts of the present invention. ... 06/28/07 - 20070148137 - Regenerated corneal endothelial cell sheets, processes for producing the same, and methods of using the same The regenerated corneal endothelial cell sheet obtained by the process will adhere very well to living tissues. ... 06/21/07 - 20070141037 - Enhanced submucosal tissue graft constructs An improved tissue graft construct comprising submucosa of a warm-blooded vertebrate and a preselected group of eukaryotic cells are described. The improved tissue graft constructs can be used in accordance with the present invention to enhance the repair of damaged or diseased tissues in vivo. ... 06/21/07 - 20070141036 - Composition and procedure for tissue creation, regeneration and repair by a cell-bearing biological implant enriched with platelet concentrate and supplements A composition and method for enhancing tissue growth, regeneration, and repair includes a Biological Glue formed by extraction of an Extremely Platelet Rich Plasma (EPRP) derived from whole blood, and subsequent activation and clotting. The Biological Glue may be utilized alone to fill defects or may be used as an ... 06/21/07 - 20070141035 - Pluripotent olfactory stem cells Disclosed is a cultured pluripotent animal cell that is prepared from nasal polyps. Also disclosed are methods for making the cell and methods of treating a brain tissue damage or of promoting cerebral angiogenesis, cerebral neurogenesis, stem cell homing to the brain, neurotrophic factor expression in the brain. ... 06/21/07 - 20070141034 - Methods for isolating t cells and uses thereof Provided herein are methods for obtaining viable populations of T cells and enriched populations of T cells. ... 06/14/07 - 20070134211 - Differentiation of adipose stromal cells into osteoblasts and uses thereof The invention provides methods and compositions for differentiating stromal cells from adipose tissue into cells having osteoblastic properties, and methods for improving a subject's bone structure. The methods comprise culturing stromal cells from adipose tissue in β-glycerophosphate and ascorbic acid and/or ascorbate-2-phosphate for a time sufficient to allow differentiation of ... 06/14/07 - 20070134210 - Production of oligodendrocytes from placenta-derived stem cells The present invention provides methods and compositions for the production of glial cells and oligodendrocytes from placenta stem cells. The invention further provides for the use of these glia and oligodendrocytes in the treatment of, and intervention in, for example, trauma, ischemia and degenerative disorders of the central nervous system ... 06/14/07 - 20070134209 - Cellular encapsulation for self-assembly of engineered tissue Methods are disclosed of producing a cellular matrix for tissue self-assembly. Encapsulated living cells are provided, with each of the living cells separately encapsulated within a primary encapsulant. The encapsulated living cells are themselves encapsulated within a liquid or gel secondary encapsulant. The second encapsulant is polymerized. ... 06/14/07 - 20070134208 - Methods for purifying hematopoietic stem cells Described herein are methods for purifying hematopoietic stem cells. Also described herein are methods for purifying EPCR+ cells. The invention also provides substantially pure isolated hematopoietic stems cells, including EPCR+ hematopoietic stem cells. ... 06/07/07 - 20070128175 - Novel hydorgels and uses thereof The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the ... 06/07/07 - 20070128174 - Methods and compositions for organ and tissue functionality Materials and methods for treating tissue defects in human or animal tissues using implantable cells are described. Further, culture techniques and factors for enhancing these procedures, and cell survival and adaptation are described. Many of the tissue defects may be treated with autologous cells, while applications involving non-autologous cells or ... 06/07/07 - 20070128173 - Use of polysulphated alginate in cellular matrices The present invention describes an in vitro/ex vivo method for the cultivation of connective tissue cells or progenitor cells (e.g. chondrogenic cells) in matrix comprising polysulphated alginate. These cultivated cells can be used in the preparation of a medicament for the treatment or prevention of osteochondral defects. The invention also ... 06/07/07 - 20070128172 - Hair growth method A method of enabling effective hair growth and furthermore, inducing hair growth closely similar to the natural hair state in the case of transplanting dermal papillae or cultured dermal papilla cells into the skin to regenerate the hair, characterized by comprising transplanting a composition containing the following components into an ... 06/07/07 - 20070128171 - Engineered blood vessels The present invention relates to engineered blood vessels and methods of making such vessels using matrices comprising endothelial and smooth muscle cells, or cells capable of differentiating into endothelial and smooth muscle cell lineages (e.g., stem cells, or the progenitors thereof). ... 05/31/07 - 20070122390 - Graft with increased resistance to enzymatic degradation Described are devices, methods, and systems for grafting tissues or organs that are exposed to bacterial or mammalian enzymes that degrade collagenous materials. Illustrative medical grafts are processed by contacting a collagenous extracellular matrix (ECM) material with a mono-carboxylic acid having from four to about twelve carbon atoms, or mixtures ... 05/31/07 - 20070122389 - Stage specific follicle maturation systems A three-dimensional matrix system is described herein. The system is used to surround developing tissue and support continued interaction between, for example, an oocyte and a supporting cellular structure. Oocytes grown to maturity can then be retrieved from the matrix for subsequent research use and/or fertilization. The systems and methods ... 05/31/07 - 20070122388 - Tissue graft compositions and methods for producing same A tissue graft composition is described herein that includes a segment of small intestinal submucosa having at least one nanoparticle incorporated therein such that the permeability of the segment of small intestinal submucosa is altered, thereby providing the segment of small intestinal submucosa with a more substantially uniform structure for ... 05/31/07 - 20070122387 - Hair grafts derived from plucked hair The present invention is a hair graft derived from a plucked hair comprising a plucked hair having adhered epidermal stem cells and associated follicular dermal cells. The present invention also includes methods of making a hair graft, methods of implanting a hair graft and methods of identifying inductive follicular dermal ... 05/31/07 - 20070122386 - Preparation method of a hair dermal papilla cell preparation, composition and method for regenerating hair follicles, and animal having regenerated hair follicles The present invention provides a method for preparing a hair dermal papilla cell preparation comprising preparing a cell suspension by removing epidermal tissue from skin tissue and subjecting the resulting dermal tissue fraction to collagenase treatment, and cyropreserving the cell suspension to kill the follicular epidermal cells. The present invention ... 05/24/07 - 20070116685 - Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith Isolated, mammalian, bone marrow-derived, hematopoietic stem cell populations contain endothelial progenitor cells (EPC) capable of forming retinal blood vessels. At least about 50% of the cells in the isolated cell population express CD31 and c-kit. Up to about 8% of the cells can express Sca-1, and up to about 4% ... 05/24/07 - 20070116684 - Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof The present invention is directed to pluripotent fetal stem cells derived from chorionic villus, amniotic fluid, and placenta and the methods for isolating, expanding and differentiating these cells, and their therapeutic uses such as manipulating the fetal stem cells by gene transfection and other means for therapeutic applications. ... 05/24/07 - 20070116683 - Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof The present invention is directed to pluripotent fetal stem cells derived from chorionic villus, amniotic fluid, and placenta and the methods for isolating, expanding and differentiating these cells, and their therapeutic uses such as manipulating the fetal stem cells by gene transfection and other means for therapeutic applications. ... 05/24/07 - 20070116682 - Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof The present invention is directed to pluripotent fetal stem cells derived from chorionic villus, amniotic fluid, and placenta and the methods for isolating, expanding and differentiating these cells, and their therapeutic uses such as manipulating the fetal stem cells by gene transfection and other means for therapeutic applications. ... 05/24/07 - 20070116681 - Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations Various embodiments provide methods and related compositions for increasing the population size of hematopoietic stem cells (HSCs) in patients that may benefit from reconstitution of stem cells and/or differentiated cells of the blood lineage. The present methods enable the production of HSCs ex vivo and in vivo by reducing latexin ... 05/24/07 - 20070116680 - Stem cells within gel microenvironments This invention provides a system to embed stem cells within three-dimensional (3D) hydrogel microenvironments consisting of naturally derived proteins, proteoglycans and/or polysaccharides. Pure matrices or combinations of materials can be used. The method involves suspending stem cells in solutions of the matrix components of interest, emulsifying these solutions in a ... 05/24/07 - 20070116679 - Augmentation of organ function The present invention provides methods and compositions for augmenting organ functions using small-scale matrix implants generated by seeding tissue-specific or undifferentiated cells onto a matrix materials (e.g., a wafer, sponge, or hydrogel). The seeded matrix composition can then be implanted and will develop into an organ-supplementing structure in vivo. Continued ... 05/24/07 - 20070116678 - Medical device with living cell sheet A novel method, using a thermoreversible MC/PBS/Collagen hydrogel coated on the TCPS dish, for harvesting a living cell sheet with ECM. The obtained living cell sheet is administered to a joint adapted for implantation and for cartilage regeneration. ... 05/24/07 - 20070116677 - Brain tissue damages A method of treating brain tissue damage, including administering to a subject in need thereof an effective amount of secretoneurin. Disclosed are methods of promoting angiogenesis or neurogenesis in the brain of subject. Also disclosed are a method of homing of stem cells to the brain of a subject and ... 05/24/07 - 20070116676 - Method for three-dimensional cartilage tissue engineering using bone marrow cells in tissue engineering bone marrow cells in simulated microgravity environment This invention provides a method for three-dimensional cartilage tissue engineering by culturing bone marrow cells in a simulated microgravity environment that is realized by a bioreactor such as an RWV. ... 05/24/07 - 20070116675 - Drug and method for proliferating natural killer cells NK cells are obtained by administering a Toll-like receptor ligand such as polyinosinic-polycytidylic acid into the peritoneal cavity of an animal to which lactoferrin has been administered to proliferate NK cells in the peritoneal cavity and collecting NK cells from the peritoneal cavity. ... 05/24/07 - 20070116674 - Use of adipose tisue cells for initiating the formation of a fuctional vascular network The invention relates to the use of cells of a medullary or extra-medullary white adipose tissue, in particular of an extra-medullary stromal vascular fraction (SVF) and/or mature dedifferentiated adipocytes of any origin for initiating the formation of a functional vascularisation. ... 05/17/07 - 20070110732 - Use of synovium and omentum for tissue engineering A method for treating a patient to repair or regenerate damaged tissues or organs in which synovium from a joint or omentum from the abdomen are harvested to provide explants, optionally separating cells from the synovium or omentum explants for culture or tissue specification, and introducting the explants or separated ... 05/17/07 - 20070110731 - Integument cell regeneration formulation The invention relates to a composition-of-matter and method of using a topical composition having 10-99 999% by weight of a topical base formulation and other active ingredients including stem cell or growth factors and/or antioxidants, as well as others for the purpose of regenerating integument cells ... 05/17/07 - 20070110730 - Multipotent stem cells from peripheral tissues and uses thereof This invention relates to multipotent stem cells, purified from the peripheral tissue of mammals, and capable of differentiating into neural and non-neural cell types. These stem cells provide an accessible source for autologous transplantation into CNS, PNS, and other damaged tissues. ... 05/17/07 - 20070110729 - Multipotent stem cells derived from human adipose tissue and cellular therapeutic agents comprising the same This invention relates to human adipose tissue-derived multipotent adult stem cells. More particularly, the invention relates to human adipose tissue-derived multipotent stem cells, which can be maintained in an undifferentiated state for a long period of time by forming spheres and have high proliferation rates, as well as methods for ... 05/17/07 - 20070110728 - Method for preventing and treating diabetes using dg119 The present invention relates generally to methods for preventing and/or treating pancreatic disorders, particularly those related to diabetes, by administering a DG119-1 product or a DG119-1 agonist and/or an antagonist To a DG 119-2 product. ... 05/17/07 - 20070110727 - Multipotent stem cells isolated from umbilical cord blood and the cellular therapeutic agent comprising the same for treating ischemic disease The present invention relates to multipotent stem cells, adult stem cells isolated by culturing umbilical cord blood in a medium containing human serum or plasma, and a cellular therapeutic agent for ischemic necrosis resulting from occlusive arterial disease, which contains the multipotent stem cells as active ingredients. The multipotent stem ... 05/10/07 - 20070104695 - Breast augmentation and reconstruction system A breast template for delivering stem cell formulation to a breast defect of a patient for treating or augmenting a breast tissue defect comprising a flexible band with at least one throughput hole for guiding an injecting needle to penetrate into the breast of the patient, wherein the flexible band ... 05/10/07 - 20070104694 - Breast stimulation and augmentation system A stem-cell-seeded porous scaffold implant and electromagnetic growth stimulation for treating or augmenting a breast tissue defect in a patient. ... 05/10/07 - 20070104693 - Breast augmentation system A stem-cell-seeded porous scaffold implant and delivery systems for treating or augmenting a breast tissue defect in a patient. ... 05/10/07 - 20070104692 - Breast tissue regeneration A stem-cell-seeded porous scaffold implant and methods for treating a breast tissue defect in a patient. ... 05/10/07 - 20070104691 - Follicular fluid for prolonged growth and survival of cells for cell therapies The invention provides a method for preventing senescence and death of somatic cells by culturing the cells in the presence of serum and follicular fluid or components of follicular fluid. The somatic cells with a limited lifespan in vitro acquire properties of stem cells and can be passaged continuously, but ... 05/03/07 - 20070098699 - Process for preparing bone marrow stem cells, and composition related thereto Process for preparing a composition comprising TVEMF-expanded bone marrow stem cells, anti the composition resulting therefrom. ... 05/03/07 - 20070098698 - Pregnancy-induced oligodendrocyte precursor cell proliferation regulated by prolactin The present invention relates to a method to increase oligodendrocytes and oligodendrocyte precursor cells through administration of prolactin or a prolactin inducing agent. ... 05/03/07 - 20070098697 - Preventing transfusion related complications in a recipient of a blood transfusion This invention is directed toward a process for reducing transfusion related complications in a recipient of an allogeneic blood transfusion by adding to the blood to be transfused a photosensitizer comprising riboflavin, irradiating the blood and riboflavin with light, transfusing the irradiated blood into a recipient, and reducing a transfusion ... 05/03/07 - 20070098696 - Immortalized fibroblasts Aspects of the invention provide an immortalized fibroblast cell line capable of the growth and maintenance of human embryonic stem cells. An immortalized fibroblast cell line derived from an early stage mouse embryo is provided. Methods of preparing an immortalized fibroblast cell line from an early stage mouse embryo are ... 05/03/07 - 20070098695 - Methods of islet separation during isolation The present invention relates to methods for improving the viability and recovery of islets that are separated from a donor organ for subsequent transplantation. In a preferred embodiment, the islets are separated from a donor pancreas and transplanted into the liver of a diabetic patient. A protective agent is mixed ... 05/03/07 - 20070098694 - Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant The present invention describes devices, solutions, and methods for the ex-vivo assessment, resuscitation, triage, and maintenance of human candidate cadaveric hearts. ... 05/03/07 - 20070098693 - Methods for enhancing engraftment of purified hematopoietic stem cells in allogenic recipients CD8+/TCR− bone marrow cells facilitate engraftment of hemapoietic stem cells (HSQ in allogeneic recipients without causing graft versus host disease. The present invention identifies the main subpopulation (55-65%) of CD8+/TCR− facilitating cells (FQ as plasmacytoid precursor dendritic cells (p-preDC). The present invention notably demonstrates that FC and p-preDC share many ... 04/26/07 - 20070092497 - Cytotherapeutics, cytotherapeutic units and methods for treatments using them The present invention provides cytotherapeutic units comprising predetermined numbers of selected types of potent cells. Assurance of the nature and identities of such cells is achieved through assay and certification of said numbers and identities. Therapeutic modalities are provided. Libraries of cell preparations with assayed and preferably certified populations are ... 04/26/07 - 20070092496 - Method of delivering cells to the skin The present invention is a method of forming egressing hair shafts comprising making a wound in the skin and placing hair follicle progenitor cells on the wound, wherein an egressing hair shaft is formed from the hair follicle progenitor cells. The present invention is also a method of forming new ... 04/26/07 - 20070092495 - Methods for regulating differentiation of neural cells and uses thereof The present invention provides methods for promoting or suppressing differentiation of neural stem/progenitor cells, for producing differentiated neural cells, and for isolating/purifying differentiated neural cells. Also provided are differentiated neural cells, cell populations and transgenic animals comprising same, and uses of same. The present invention further provides methods for treating ... 04/26/07 - 20070092494 - Composition for wound healing using lyophilized skin or skin-derived collagen A wound healing composition for repairing a wound in a human or animal subject, comprising a first skin tissue material and a carrier comprising collagen derived from a second skin tissue material. Methods of making the wound healing composition and methods of augmenting a wound site with the composition are ... 04/26/07 - 20070092493 - Living cell sheet A novel method, using a thermoreversible MC/PBS/Collagen hydrogel coated on the TCPS dish, for harvesting a living cell sheet with ECM. The coated hydrogel system is reusable and can be used for culturing a multi-layer cell sheet. The obtained living cell sheets may be used for tissue reconstructions. ... 04/26/07 - 20070092492 - Three-dimentional tissue structure The present invention provides a prosthetic tissue or sheet capable of withstanding implantation operations, which can be used in actual operation and can be produced by culture. The present invention also provides a novel therapy which can substitute for cell therapy. Particularly, the present invention provides a method for producing ... 04/19/07 - 20070086987 - Skeletal musle-derived cells and methods related thereto The disclosure provides methods of propagating skeletal muscle cell (SkMC) cultures enriched in differentiation-competent myoblasts that express normal levels of CD56 and reduced levels of desmin. The methods comprise culturing SkMCs in a mitogen-rich cell culture medium supplemented with TGF-β. The disclosure also provides therapeutic methods utilizing SkMCs propagated in ... 04/19/07 - 20070086986 - Preparation of three-dimensional mammalian ovarian follicular cell and ovarin follicle culture systems in a biocompatible matrix A process for encapsulating and immobilising mammalian stem cells, ovarian follicular cells, gametes, ovarian follicles or mammalian embryos which are able to auto-organise into three-dimensional structures in vitro, and express biological functions in a manner similar to that which is observed in the organism in vivo is described. The capsules ... 04/12/07 - 20070081980 - Culture cells from pancreatic islets A cell composition of endocrine progenitor cells derived from mammalian pancreatic islet cells that can be trans-planted planted into a diabetic patient such t the cells of the cell composition differentiates into functioning insulin-producing beta cells. ... 04/12/07 - 20070081979 - Multi-functional chimeric hematopoietic receptor agonists Disclosed are novel multi-functional chimeric hematopoietic receptor agonist proteins, DNAs which encode the multi-functional chimeric hematopoietic receptor agonist proteins, methods of making the multi-functional chimeric hematopoietic receptor agonist proteins and methods of using the multi-functional chimeric hematopoietic receptor agonist proteins. ... 04/05/07 - 20070077237 - Method for freezing, thawing and transplantation of viable cartilage Disclosed is a method for providing a patient having impaired cartilage in an organ at a target site, with corresponding viable cartilage, possibly osteochondral cartilage. The method comprises freezing the cartilage by cooling it at a cooling rate of 0.01° C./min to 3° C./min. Thawing of the cartilage may be ... 04/05/07 - 20070077236 - Method for cell implantation An endoscopic method for treating cartilage or bone defects in an animal, said method comprising the steps of: I) identifying the position of the defect, ii) applying cells selected from the group consisting of chondrocytes, chondroblasts, osteocytes and osteoblasts and combinations thereof into the cartilage or bone defect. In particular, ... 03/29/07 - 20070071733 - Synthetic substrate for tissue formation The invention relates to a substrate on which to grow synthetic cartilage, a method for preparing the substrate, a synthetic cartilage patch comprising the substrate, and methods of using the synthetic cartilage patch. ... 03/29/07 - 20070071732 - Secretory cell-containing macrobeads comprising seakem gold agarose, and uses thereof The invention describes the manufacture and use of secretory cell containing bead structures that are coated with agarose. The beads, which are preferably 4 mm-12 mm in diameter, and which preferably contain islets, are made of a particular agarose, i.e., Seakem Gold agarose. ... 03/29/07 - 20070071731 - Promotion of neurogenesis of endogenous and transplanted human neural stem cells Disclosed herein are methods and materials for promoting neurogenesis of endogenous and transplanted stem cells. Specifically exemplified herein are methods that comprise transplanting neural stem cells in conjunction with a regimen of (+)phenserine treatment. ... 03/29/07 - 20070071730 - Stem cells of the islets of langerhans and their use in treating diabetes mellitus Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation into a variety of pancreatic islet cells, including insulin-producing beta cells, as well as hepatocytes. Nestin has been identified as a molecular marker ... 03/29/07 - 20070071729 - Dermal fillers for biomedical applications in mammals and methods of using the same A method of tissue augmentation in mammals comprising implanting or injecting into the tissue of a mammal elastic material derived from solar elastosis or other sun-damaged sites in humans is disclosed. The method further comprises injecting into the tissue of a mammal, alone, or in combination with the solar elastosis, ... 03/29/07 - 20070071728 - Biomimetic nanocomposite A biomimetic nanocomposite including hydroxyapatite nanocrystals, gelatin, and polymer, wherein the biomimetic nanocomposite is crosslinked is described. Also described is a process for making the nanocomposite. Additionally, a method for using the nanocomposite, and articles formed from the nanocomposite are also described. ... 03/29/07 - 20070071727 - Melanocytes in therapy of neurodegenerative diseases In vitro cultivation method for producing human melanocytes which are capable of melanin and/or L-dopa synthesis, and to various uses of said melanocyte(s). In one preferred aspect, said melanocyte(s) are used in an autologous implantation method in a patient suffering from a neurodegenerative disease, e.g. Parkinson's disease. In another aspect, ... 03/22/07 - 20070065420 - Ultrasound therapy resulting in bone marrow rejuvenation A method and system for treating a patient to repair damaged tissue which includes exposing a selected area of bone marrow of a patient to ultrasound waves or ultra shock waves so that cells comprising stem cells, progenitor cells or macrophages are generated in the area of the bone marrow ... 03/22/07 - 20070065419 - Keratinocytes useful for the treatment of wounds The invention relates to new keratinocytes which may be cultured in vitro and the advantageous use thereof for preparing a product which can be used to treat acute and chronic wounds. ... 03/22/07 - 20070065418 - Method and device for cellular therapy A device and method for performing a therapeutic treatment at a treatment site in a patient's vessel, the device configured to be introduced by means of a catheter, the device including an expandable portion capable of being expanded between a contracted position and a deployed position at the treatment site, ... 03/22/07 - 20070065417 - Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying ... 03/22/07 - 20070065416 - Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying ... 03/22/07 - 20070065415 - Compositions and methods for the augmentation and repair of defects in tissue Compositions and methods of treating a defect in a patient are disclosed, including expanding a culture of autologous cells in vitro to form cultured cells, collecting the cultured cells for introduction into the patient, and depositing the cultured cells with ancillary proteins. ... 03/22/07 - 20070065414 - Enhanced delivery of cells The present invention provides a method comprising administering cells by infusion through a blood vessel and administering a vasodilator, a vascular enhancer, or both. In accordance with one embodiment, the delivery of stem cells to the myocardium by intracoronary infusion is improved by administration of one or more vasodilators and/or ... 03/15/07 - 20070059293 - Tissue engineered construct for supplementing or replacing a damaged organ The present invention provides methods and compositions for supplementing or replacing a damaged organ. The damaged organ to be supplemented or replaced in accordance with the present invention include, for example, kidney, heart, liver, spleen, pancreas, bladder, ureter and urethra. In one embodiment, the tissue-engineered construct of the invention has ... 03/08/07 - 20070053888 - Use of umbilical cord blood to treat individuals having a disease, disorder or condition The present invention provides methods of using cord blood and cord blood-derived stem cells in high doses to treat various conditions, diseases and disorders. The high-dose cord blood and cord blood-derived stem cells have a multitude of uses and applications, including but not limited to, therapeutic uses for transplantation and ... 03/08/07 - 20070053887 - Method for production of neuroblasts A method for producing a neuroblast and a cellular composition comprising an enriched population of neuroblast cells is provided. Also disclosed are methods for identifying compositions which affect neuroblasts and for treating a subject with a neuronal disorder, and a culture system for the production and maintenance of neuroblasts. ... 03/08/07 - 20070053886 - Biological bypass bridge with sodium channels, calcium channels and/or potassium channels to compensate for conduction block in the heart This invention provides a bypass bridge comprising a tract of gap junction-coupled cells having a first end and a second end, both ends capable of being attached to two selected sites in a heart so as to allow the conduction of a pacemaker and/or electrical signal/current across the tract between ... 03/08/07 - 20070053885 - Mesenchymal stem cell It is intended to obtain a mesenchymal stem cell in the early stage of differentiation from a pluripotent stem cell differentiated in vitro. A mesenchymal stem cell is obtainable by: a) the step of culturing pluripotent stem cells, b) the step of confirming the appearance of a cell with stroma ... 03/08/07 - 20070053884 - Novel adult tissue-derived stem cell and use thereof Subjects of the present invention are to establish a technology for separating, isolating and culturing a stem cell derived from adult tissue while retaining the in vivo properties thereof, and to provide a preventive and/or therapeutic agent for diseases which accompany tissue injury, which comprises a stem cell derived from ... 03/08/07 - 20070053883 - Neuronal cell lineages and methods of production thereof Methods are provided in which a sterol-depleting agent such as β-cyclodextrin (βCD), is used to modulate signaling by a differentiation signaling protein such as Hedgehog protein or a BMP in vitro. As illustrated herein, the use of βCD in conjunction with Sonic Hedgehog N-terminal peptide (ShhN) causes substantially all of ... 03/01/07 - 20070048292 - Cell-containing sheet In accordance with the present invention, an implant in which cells are arranged in a fine pattern that is available for immediate implantation and that does not need to be removed after implantation is provided. The present invention relates to a cell-containing sheet, which comprises cells and a support comprising ... 03/01/07 - 20070048291 - Method and material for enhanced tissue-biomaterial integration The present invention relates to the covalent binding of a hydrogel to an extracellular matrix (ECM). The integration of the hydrogel with the tissue is superior to that in previous techniques. Moreover, unlike previous techniques, the present invention does not require a photoinitiator. Potential therapeutic applications include tissue repair and ... 03/01/07 - 20070048290 - Development of natural killer cells and functional natural killer cell lines The invention relates to natural killer cells and methods for the development of immortalized natural killer cells and use of the natural killer cells. A growth and culture system is described that supports increased natural killer cell development, and provides for the establishment of continuous natural killer cell lines. Additionally, ... 03/01/07 - 20070048289 - Cellular intervention to treat damaged myocardium A system and method for treating damage myocardial tissue includes delivering replacement cells to the myocardium of a patient and electrically stimulating the spinal column of the patient to affect a cellular environment within the myocardium. ... 03/01/07 - 20070048288 - Shear thinning polymer cell delivery compositions Cell delivery compositions including shear thinning polymers and their use in cell delivery are described. The cell delivery compositions include shear thinning polymers that confer higher viscosity when at rest and decreased viscosity when subject to shear stress when dissolved or suspended in a carrier liquid. These shear thinning properties ... 02/22/07 - 20070041956 - Vaccine immunotherapy for immune suppressed patients A method for overcoming mild to moderate immune suppression includes the steps of inducing production of naïve T-cells and restoring T-cell immunity. A method of vaccine immunotherapy includes the steps of inducing production of naïve T-cells and exposing the naïve T-cells to endogenous or exogenous antigens at an appropriate site. ... 02/22/07 - 20070041955 - Hedgehog signaling promotes the formation of three dimensional cartilage matrices The present invention provides methods and compositions for promoting the formation of three dimensional cartilage matrices. The present invention further provides methods of treating diseases and injuries involving cartilage and bone using the three dimensional cartilage matrices provided herein. ... 02/22/07 - 20070041954 - Compositions of placentally-derived stem cells for the treatment of cancer Disclosed are preparations of placentally-derived stem cells and compositions useful for the treatment of cancer. Said stem cells and compositions function through inducing a “guided differentiation” program in cancer cells, thereby reducing malignancy. Further extension of the invention pertains to augmenting ability of administered cells to induce differentiation through the ... 02/22/07 - 20070041953 - Smooth muscle progenitor cells Purified populations of smooth muscle progenitor cells are provided as well as methods of making and using the cells. ... 02/22/07 - 20070041952 - Three-dimensional fiber scaffolds for tissue engineering A tissue restoration implant adapted for use with a pre-determined tissue, and methods of making and using the same. The tissue restoration implant adapted for use with a pre-determined tissue can include a three-dimensional fiber scaffold, the scaffold comprising at least three systems of fibers; wherein two of the three ... 02/22/07 - 20070041951 - Differentiation of non-insulin producing cells into insulin producing cells by glp-1 or exendin-4 and uses thereof The present invention relates to a population of insulin producing cells made by a process comprising contacting non-insulin producing cells with a growth factor selected from the group consisting of GLP-1 or Exendin-4, growth factors having amino acid sequences substantially homologous to GLP-1 or Exendin-4, and fragments thereof. The present ... 02/22/07 - 20070041950 - Method and device for selective addition of a bioactive agent to a multi-phase implant A method and device for assembling a multi-phase implant for insertion into a patient defect site that spans more than one tissue type. The assembly device comprises a base and cover portion for constructing a two-phase implant separated by a membrane. A repeating intermediate portion that connects the base and ... 02/22/07 - 20070041949 - Ultrasonic modification of soft tissue matrices The present invention provides a method of, and apparatus for, utilising ultrasonic energy so as to mechanically disrupt the collagenous architecture of biological matrices in a controlled manner so that the tissue can be rapidly recellularised in continuous form. The present invention also provides for the production of tissue matrices ... 02/22/07 - 20070041948 - Method for culturing and proliferating hematopoietic stem cells and progenitor cells using human endometrial cells Disclosed herein is a method for culturing and proliferating hematopoietic stem cells or progenitor cells. The method comprises co-culturing the hematopoietic stem cells or the progenitor cells with human endometrial stromal cells so as to promote the expansion of hematopoietic stem cell-derived CD34+ cells or the growth of the progenitor ... 02/15/07 - 20070036768 - Systems and methods for treating patients with processed lipoaspirate cells Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are ... 02/15/07 - 20070036767 - Postpartum cells derived from umbilical cord tissue, and methods of making and using the same Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. ... 02/15/07 - 20070036766 - Tissue graft composition comprising autologous bone marrow and purified autologous thrombin A method for the preparation of an autologous tissue graft composition is disclosed. Bone marrow is harvested from the patient. In one embodiment, the nucleated cells of the bone marrow are subsequently concentrated. Autologous thrombin is purified from a volume of whole blood also taken from the patient. The bone ... 02/15/07 - 20070036765 - Therapeutic and diagnostic applications of genes differentially expressed in lympho-hematopoietic stem cells The invention is based at least in part on the discovery of novel group of genes and/or their encoded gene products that are differentially represented in two substantially enriched CD34+/CD38−/Lin− and CD34+/[CD38/Lin]++ hematopoietic cell populations isolated from normal human bone marrow, cord blood, and peripheral blood stem cell preparations. ... 02/08/07 - 20070031389 - Transplants for myocardial scars A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart. ... 02/08/07 - 20070031388 - Cell-charged multi-layer collagen membrane A multi-layer sheet of collagen membrane material includes a barrier layer including an outer smooth barrier face and further including a fibrous face opposite the smooth barrier face, and a matrix layer of collagen material adhered to the fibrous face, the matrix layer including collagen I, collagen III, or a ... 02/08/07 - 20070031387 - Method for treating and/or preventing spinal cord injury A method of preventing or treating neurologic function deficit of vertebrates undergone spinal cord injury, comprising administering an effective amount of BM-MNCs to a vertebrate in need thereof through cerebrospinal fluid. ... 02/08/07 - 20070031386 - Modalities for the treatment of degenerative diseases of the retina This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells. ... 02/08/07 - 20070031385 - Apparatus and method to treat a wound area A method is disclosed to treat a patient having a wound area, such as a burn injury. The method provides a plurality of epidermal/dermal cells, and applies that plurality of epidermal/dermal cells to the wound area. ... 02/08/07 - 20070031384 - Regeneration of pancreatic islets by amniotic fluid stem cell therapy A method of treating diabetes in a mammalian subject is carried out by: (a) providing mammalian amniotic fluid stem cells, and then (b) administering the cells to the subject in an amount effective to treat diabetes. Optionally, the cells may be differentiated into pancreatic-like cells or at least treated to ... 02/01/07 - 20070025973 - Reprogramming of adult or neonic stem cells and methods of use The present invention relates to methods of reprogramming adult stem cells or stem cells obtained from umbilical or placental cord blood or more preferably, the placeta or umbilical cord tissue itself or the amniotic fluid or amnion. The resulting stem cells and methods of using these stem cells represent additional ... 02/01/07 - 20070025972 - Methods and compositions for smooth muscle reconstruction This invention also provides a purified or isolated population of ADSCs that can differentiate into a cell of the leiomyogenic lineage, e.g., smooth muscle or skeletal muscle. In yet another aspect, the population additionally can be differentiated into a lineage selected from the group consisting of osteogenic, adipogenic, chondrogenic, myogenic ... 01/25/07 - 20070020247 - Dopaminergic neurons derived from corneal limbus, methods of isolation and uses thereof The present disclosure describes the generation of neural cells and neurons from mammalian pluripotent embryonic-like stem cells (ELSCs) isolated from corneal limbal tissue, a non-embryonic tissue. Specifically, the present disclosure describes the generation of neuroprogenitor cells and differentiated dopaminergic neurons from ELSCs. The disclosed methods demonstrate the potential of ELSCs ... 01/25/07 - 20070020246 - Use of microchimeric cells in the treatment of malignancy Methods and formulations for the treatment of malignancies. Assessment of the incidence and scope of MC in control and cancer populations provides for the development of cellular therapy approaches to hematologic malignancies that are expected to be well tolerated immunologically. Studies will confirm that parous females who display MC are ... 01/25/07 - 20070020245 - Composition for the treatment of arthrosis/arthritis, especially for treating joints The invention especially relates to a composition for the treatment of arthrosis/arthritis, especially for treating joints, said composition containing at least one carrier substance for receiving at least one anti-inflammatory agent and chondrogenetic cells, in addition to at least one anti-inflammatory agent, and chondrogenetic cells. ... 01/25/07 - 20070020244 - Fiber constructs and process of fiber fabrication Described herein are fiber compositions, methods of generating the fiber compositions, and methods of using the fiber compositions in various applications utilizing fiber constructs, including for example, tissue engineering. ... 01/25/07 - 20070020243 - Methods and compositions related to modulating the extracellular stem cell environment This invention relates, in part, to methods and compositions that modulate the stem cell environment. More specifically, the invention relates, in part, to methods and compositions for modulating stem cell differentiation. Such modulation, in some aspects of the invention, is accomplished by agents that modulate glycosaminoglycans in the stem cell ... 01/25/07 - 20070020242 - Method for transdifferentiation of non-pancreatic stem cells to the pancreatic pathway The subject invention relates to a method of transdifferentiating mammalian non-pancreatic stem cells, such a mesenchymal stem cells (MSCs), to enter the pancreatic differentiation pathway. The MSCs are cultured under conditions that permit the expression of pancreatic differentiation markers, and these conditions include use of: (a) culture conditions that promote ... 01/18/07 - 20070014772 - Engineered biografts for repair of damaged myocardium A method for repairing a damaged myocardium in a mammal, comprising: a) providing a three-dimensional porous polysaccharide matrix; b) introducing mammalian cells into said matrix; c) growing said cells in said matrix in vitro, until a tissue-engineered biograft is formed, comprising a contracting tissue; and d) transplanting the tissue-engineered biograft ... 01/18/07 - 20070014771 - Postpartum cells derived from umbilical cord tissue, and methods of making and using the same Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. ... 01/11/07 - 20070009495 - Method for treating or preventing systemic inflammation in formula-fed infants The present invention is directed to a novel method for treating or preventing systemic inflammation in a formula-fed infant. The method administering to the infant a therapeutically effective amount of LGG in combination with at least one LCPUFA. ... 01/11/07 - 20070009494 - Postpartum cells derived from umbilical cord tissue, and methods of making and using the same Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. ... 01/11/07 - 20070009493 - Chondrogenic compositions and methods of use The invention provides a method of treatment joint and disk disease comprising administering to the subject in need thereof a novel composition comprising a substantially purified plurality of cells enhanced with at least one bioactive factor capable of causing at least a portion of the plurality of cells to express ... 01/11/07 - 20070009492 - Multipotent postnatal stem cells from human periodontal ligament and uses thereof The invention generally relates to postnatal periodontal ligament stem cells and methods for their use. More specifically, the invention relates in one aspect to postnatal periodontal ligament multipotent stem cells, use of the cells to generate periodontium, differentiation of the cells and methods of tissue cryopreservation. ... 01/11/07 - 20070009491 - Platelet-derived growth factor-responsive neural precursor cells and progeny thereof This invention provides platelet-derived growth factor-responsive neural precursor (PRP) cells and methods of producing such cells in vivo or in vitro. These cells can further be used to generate neurons, oligodendrocytes and/or astrocytes. ... 01/04/07 - 20070003528 - Intracoronary device and method of use thereof Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. ... 01/04/07 - 20070003527 - Method for enhancing leukocyte immune function The present invention provides a method for enhancing the immune function of leukocytes in a subject, which comprises the steps of: (a) isolating leukocytes from the subject; (b) treating the leukocytes obtained from step (a) with an inhibitor of the endoplasmic reticulum calcium ion pump; and (c) administrating the treated ... 01/04/07 - 20070003526 - Blood vessel-specific organogenesis from embryonic stem cells on three-dimensional matrigel layer The present invention provides use of embryonic stem cells or embryonic stem cell-derived embryoid bodies cultured on growth factor-reduced Matrigel™, for treating diseases caused by ischemia or arteriosclerosis. ... 01/04/07 - 20070003525 - Hydrogel compositions comprising nucleus pulposus tissue Disclosed are methods and compositions useful in the treatment, augmentation and/or repair of soft and/or hard tissues of animals, and in particular, vertebrates such as humans. The invention provides hydrogel compositions for use in the preparation of medicaments for wound healing, cartilage and meniscus repair, dermal augmentation, and bone fusion, ... 12/28/06 - 20060292128 - Methods of treating schizophrenia The invention provides methods for the treatment of abnormal psychiatric states, particularly the negative symptoms of schizophrenia and extrapyramidal side effects (EPS) of antipsychotic drugs. The inventive methods relate to the administration of therapeutic cells (which produce dopamine or dopamine precursors) adhered to support matrices to subjects suffering from the ... 12/28/06 - 20060292127 - Beta cell growth and differentiation The invention includes methods that can be used to increase β cell populations in vivo and in vitro, useful in the treatment of diabetes and related disorders. ... 12/28/06 - 20060292126 - Epidermal and dermal equivalents The present invention relates to the treatment of skin defects by organotypically-cultured autologous keratinocytes isolated from the outer root sheath of anagen or growing hair. Methods for primary, as well as subsequent organotypic cultures (i.e., epidermal equivalents) in fully-defined media supplemented by autologous human serum and substances isolated form blood ... 12/28/06 - 20060292125 - Methods for treating ischemic tissue Compositions and methods for treating ischemic tissue are provided herein. ... 12/21/06 - 20060286079 - Use of cytokines and mitogens to inhibit pathological immune responses The invention is generally related to methods of treating autoimmune diseases, including both antibody-mediated and cell-mediated disorders. ... 12/21/06 - 20060286078 - Methods of treating cardiorenal syndrome and hepatorenal syndrome A method of treating a patient with cardiorenal syndrome and hepatorenal syndrome are provided in which a portion of the body fluid of the patient is exposed to renal epithelial cells, outside of the kidney of the patient, whereby the body fluid is in fluid communication with renal epithelial cells ... 12/21/06 - 20060286077 - Perivascular mesenchymal precursor cell induced blood vessel formation Mesenchymal precursors cells have been isolated from perivascular niches from a range of tissues utilizing a perivascular marker. A new mesenchymal precursor cell phenotype is described characterized by the presence of the perivascular marker 3G5, and preferably also alpha smooth muscle actin together with early developmental markers such as STRO-1 ... 12/14/06 - 20060280727 - Dendritic cell isolation methods Disclosed are methods for isolating dendritic cells and/or dendritic progenitor cells. The methods include contacting a population of cells with a plurality of FRIL family member molecules, and removing the unbound cells, wherein the cells bound to the FRIL family member molecules are an isolated population of dendritic cells and/or ... 12/14/06 - 20060280726 - Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying ... 12/07/06 - 20060275273 - Intervertebral disc repair, methods and devices therefor The present application discloses compositions, methods and devices for treatment of a degenerative intervertebral disc. A composition can comprise chondrocytes expressing type II collagen. These chondrocytes can be obtained from human cadavers up to about two weeks following death, and can be grown in vitro. The compositions can further comprise ... 12/07/06 - 20060275272 - Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases The present invention relates to a treatment of an autoimmune demyelinating disease/disorder. Also included in the present invention is the use of bone marrow stromal cells for the treatment of multiple sclerosis (MS). ... 12/07/06 - 20060275271 - Plasma-depleted, non-red blood cell-depleted cord blood compositions and methods of use The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are not depleted from the UCB unit. Such UCB units can be prepared by a process that combines plasma ... 12/07/06 - 20060275270 - In vitro mucosal tissue equivalent The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with pathogens and vaccines in mammals. The artificial immune system can be used to test the efficacy of ... 12/07/06 - 20060275269 - Method and data system for the treatment at birth of a patient who is identified at birth as having an elevated risk of a previously unidentified disorder The present invention provides a procedure used in the overall treatment of a patient who is identified at birth as having an elevated risk of a previously unidentified disorder and method of using a data system to assist in the procedure. In a preferred embodiment, the procedure involves, at the ... 12/07/06 - 20060275268 - Compositions for activating the infiltration activity of dendritic cells, and immunopotentiating agents The present invention's compositions for activating the infiltration activity of dendritic cells comprise retinoid. Retinoid increases the production of MMP-9, which is required for dendritic cells to exert their infiltration activity, and thereby activates the dendritic cells' infiltration activity. Therefore, the compositions exhibit immunopotentiating effects and can be used in ... 11/30/06 - 20060269527 - Isolation of cells from bone The present invention provides a method for isolating cells from bone(s) harvested from a mammal. The method comprising the steps of: (a) obtaining a bone(s) containing bone marrow from the mammal; (b) fragmentation of the bone(s); (c) washing the bone fragments produced from step (b) and recovery of dislodged cells; ... 11/30/06 - 20060269526 - Stromal antigen-presenting cells and use thereof There is provided a stromal antigen-presenting cell capable of antigen presentation in the context of MHC II. When stimulated with IFNγ the stromal cell expresses B7-H1 and/or CD80. These stromal cells can be used to generate an immune response in an animal. ... 11/30/06 - 20060269525 - Co-grafts for treating parkinson's disease This invention relates to a graft for treating Parkinson's Disease, wherein, in one embodiment, the graft contains an effective amount of both a) adrenal chromaffin cells (ACCs), and b) olfactory ensheathing cells (OECs), and GDF-5. ... 11/30/06 - 20060269524 - Composition for nkt cell activation R2 represents hydrogen, or α-galactose, α-glucose, α-mannose, α-glucosamine, β-glucosamine or a combination thereof. ... 11/23/06 - 20060263341 - Selected cell delivery for heart failure This invention provides methods of increasing blood flow to tissue in a subject in need thereof, methods of regenerating tissue in a subject, methods of treating diseased tissue in a subject, methods of forming new blood vessels in tissue and new tissue, such as myocardial tissue, in a subject in ... 11/23/06 - 20060263340 - Treating gastrointestinal diseases with modulators of retinoic acid T cells are programmed to target the gastrointestinal tract by activation with dendritic cells capable of producing and/or transporting retinoic acid. Methods for using the programmed dendritic cells and/or T and/or B cells to treat a variety of pathogens and infectious agents residing in the intestine are also disclosed. Similarly, ... 11/23/06 - 20060263339 - Recovery of tissue function following administration of b cells to injured tissue The present invention relates generally to systems and methods of enhancing recovery of function of injured tissue through administration of a composition comprising a relatively pure populations of B lymphocyte cells in a pharmaceutically acceptable carrier to the injured tissue. Kits are provided to aid in purification of B cells ... 11/23/06 - 20060263338 - Catheter-based delivery of skeletal myoblasts to the myocardium of damaged hearts The present invention provides improved systems and methods for the minimally invasive treatment of heart tissue deficiency, damage and/or loss, especially in patients suffering from disorders characterized by insufficient cardiac function, such as congestive heart failure or myocardial infarction. In certain embodiments, a cell composition comprising autologous skeletal myoblasts and, ... 11/23/06 - 20060263337 - Immunomodulatory properties of multipotent adult progenitor cells and uses thereof Isolated cells are described that are not embryonic stem cells, not embryonic germ cells, and not germ cells. The cells can differentiate into at least one cell type of each of at least two of the endodermal, ectodermal, and mesodermal lineages. The cells do not provoke a harmful immune response. ... 11/23/06 - 20060263336 - Cell targeting methods and compositions In certain aspects, the invention relates to cell delivery compositions comprising a progenitor cell and a targeting moiety, and methods related thereto. Such compositions and methods may be used, for example, in administering a targeted cell therapy to a subject. ... 11/23/06 - 20060263335 - Porous matrix A porous matrix suitable for use as a tissue scaffold is described. The matrix may be shaped before insertion into or at the target tissue site, or injected via a minimally invasive method. The matrix may be pre-seeded with cells of the target tissue or may be used to support ... 11/16/06 - 20060257379 - Surgical system for the preparation of an implant and method for the preparation of an implant In order to improve a surgical system for the preparation of an implant for filling a defect on a bone and/or a cartilage of a human or animal body formed as a result of a trauma and/or degeneration, so that the defect can be filled with the implant with as ... 11/16/06 - 20060257378 - Adaptive sol-gel immobilization agents for cell delivery The present invention relates to formulations which form hydrogels at physiological temperatures. More specifically, the present invention relations to formulations having a prepolymer, an additive, and a temperature protectant, wherein the prepolymer and additive polymerize at physiological conditions to form a hydrogel. The formulations can further comprise cell suspensions such ... 11/16/06 - 20060257377 - Production of tissue engineered digits and limbs The invention pertains to methods of producing artificial composite tissue constructs that permit coordinated motion. Biocompatable structural matrices having sufficient rigidity to provide structural support for cartilage-forming cells and bone-forming cells are used. Biocompatable flexible matrices seeded with muscle cells are joined to the structural matrices to produce artificial composite ... 11/16/06 - 20060257376 - Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem ... 11/09/06 - 20060251629 - Muscle-based grafts/implants The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for ... 11/09/06 - 20060251628 - Defatted, dewatered bone marrow Bone marrow aspirate from which water and fat have been substantially removed. ... 11/02/06 - 20060246042 - Cells, culture methods, and their use in autologous transplantation therapy The present invention provides use of a host cell population obtained from a non-diseased host organism for the preparation of a cell-composition for use in subsequent autologous transplantation therapy of said host organism. ... 11/02/06 - 20060246041 - Methods and reagents for tissue engineering of cartilage in vitro The present invention makes available an optimal concentration of a hedgehog polypeptide for modulating growth and/or cartilage production by chondrocytes. The present invention allows for improvements in the culturing of chondrocytes to develop cartilaginous tissue ex vivo suitable for implantation to replace damaged or deteriorated cartilage in a patient. ... 10/26/06 - 20060239983 - Methods and compositions for the repair and/or regeneration of damaged myocardium Methods, compositions, and kits for repairing damaged myocardium and/or myocardial cells including the administration cytokines are disclosed and claimed. Methods and compositions for the development of large arteries and vessels are also disclosed and claimed. The present application also discloses and claims methods and media for the growth, expansion, and ... 10/26/06 - 20060239982 - Debulking catheters and methods A debulking catheter comprising a tissue debulking assembly for removing a continuous strand of material from a body lumen. Catheters of the present invention generally include a catheter body having proximal and distal portions and a tissue debulking assembly disposed at least partially within the distal portion. The tissue debulking ... 10/26/06 - 20060239981 - Bioreactor system and method of enhancing functionality of muscle cultured in vitro A method of producing organized skeletal muscle tissue from precursor muscle cells in vitro comprises: (a) providing precursor muscle cells on a support in a tissue media; then (b) cyclically stretching and relaxing the support at least twice along a first axis during a first time period; and then (c) ... 10/26/06 - 20060239980 - Cartilage-derived stem cells and applications thereof The invention relates to methods of isolating adult stem cells, to the cells thus isolated and to applications thereof. More specifically, the invention relates to isolated adult stem cells, which are derived from dedifferentiated chondrocytes, which can be differentiated and which can give rise to a series of cell lineages, ... 10/26/06 - 20060239979 - Dendritic cell presenting a-glycosylceramide derivative and antigent and usable in suppressing immune response The present invention relates to dendritic cell and cell mixture which is capable of suppressing T cell-dependent immune response specific for an antigen. The dendritic cell according to the present invention is a dendritic cell capable of suppressing T cell-dependent immune response specific for an antigen, which presents antigen fragment ... 10/26/06 - 20060239978 - Gene expressed specifically in dopamine-producing neuron precursor cells after termination of division A novel gene 65B13 expressed specifically and transiently in dopaminergic neuron precursor cells immediately after cell cycle exit was obtained by the present invention. The cellular expression of 65B13 can be used as an index to select cells that are suitable in terms of their safety, survival rate, and network ... 10/19/06 - 20060233769 - Established cell line of microglia A subcultivatable, established microglia having the following properties. (a) Form: Both or either of a macrophage-like or spherical form in the presence of a granulocyte-macrophage colony stimulation factor and a branched form similar to branched microglia present in the brain in the absence of the factor. (b) Functional characteristics: specific ... 10/19/06 - 20060233768 - Elective collection and banking of autologous peripheral blood stem cells An elective healthcare insurance model using an individual's own peripheral blood stem cells for the individual's future healthcare uses. An individual can elect to have his or her own stem cells collected, processed and preserved, while he or she is in healthy or “pre-disease” state, for future distribution for his ... 10/19/06 - 20060233767 - Process for producing a tissue transplant construct for reconstructing a human or animal organ A process for producing a tissue transplant construct for reconstructing a human or animal organ. The process may include the steps of: (a) isolation and two-dimensional cultivation of organ-specific tissue cells; (b) application of the organ-specific tissue cells to a biocompatible, collagen-containing membrane; and, (c) cultivation of the organ-specific tissue ... 10/19/06 - 20060233766 - Treatment of parkinson's disease and related disorders using postpartum derived cells Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to treat patients having a neurodegenerative condition of the substantia nigra or striatum, such as Parkinson's disease, are provided. ... 10/19/06 - 20060233765 - Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells Cells derived from postpartum tissue such as the umbilical cord and placenta, and methods for their use to regenerate, repair, and improve neural tissue, and to improve behavior and neurological function in stroke patients are disclosed. ... 10/19/06 - 20060233764 - Skin regeneration system A cell culture medium and system are provided which eliminate or at least reduce the requirem |