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Drug, Bio-affecting And Body Treating Compositions > Whole Live Micro-organism, Cell, Or Virus Containing > Virus Or Bacteriophage

Virus Or Bacteriophage

Virus Or Bacteriophage patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

03/27/14 - 20140086880 - Method for treating neurodegenerative tauopathy
The present invention is directed to a filamentous bacteriophage for use in treating a neurodegenerative tauopathy or susceptibility to a neurodegenerative tauopathy and a method of using the bacteriophage for reducing the formation of fibrils of tau protein or for disaggregating pre-formed fibrils of tau protein, such as in a...

03/20/14 - 20140079671 - Antibacterial phage, phage peptides and methods of use thereof
The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage...

02/27/14 - 20140056854 - Viral vectors with modified transduction profiles and methods of making and using the same
The present invention provides AAV capsid proteins, virus capsids comprising said capsid proteins and virus vectors comprising said capsid proteins, wherein the AAV capsid proteins have one or more mutations, wherein the mutation(s) result in a phenotype of decreased liver transduction and/or reduced glycan binding affinity as compared to a...

02/13/14 - 20140044680 - Simian subfamily b adenoviruses sadv-28, -27, -29, -32, -33, and -35 and uses thereof
A recombinant vector comprises simian adenovirus 28, simian adenovirus 27, simian adenovirus 32, simian adenovirus 33, and/or simian adenovirus 35 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses one or more simian adenovirus-28, -27, -32, -33, or -35 genes is also disclosed....

02/06/14 - 20140037587 - Beneficial effects of bacteriophage treatments
The invention relates to use of one or more bacteriophages in vivo in a human or animal in order to induce sensitivity to chemical antibiotics in bacterial cells, where such susceptibility is heritable, independent of continuing bacteriophage metabolism within those cells, and does not relate to the destruction of a...

02/06/14 - 20140037588 - Injectable thermoresponsive polyelectrolytes
Provided herein are compositions, devices and systems comprising thermoresponsive, biodegradable elastomeric materials, and methods of use and manufacture thereof....

01/30/14 - 20140030229 - New clone of newcastle disease virus, its manufacture and its application in the medical treatment of cancer
A new clone of Newcastle disease virus which is interferon insensitive and has an ICPI between 1.2 and 2.0 and which may be used in the treatment of cancer and other diseases....

01/30/14 - 20140030230 - Avian metapneumovirus in oncolysis
The present invention relates to live avian metapneiunovirus (AMPV) for use in cancer therapy and to pharmaceutical compositions for use in cancer therapy comprising a cytotoxic amount of live avian metapneumovims (AMPV) and a pharmaceutically acceptable carrier...

01/16/14 - 20140017205 - Bacteriophage and antibacterial composition comprising the same
Disclosed herein is a novel bacteriophage which has specific bactericidal activity against one or more Salmonella bacteria selected from the group consisting of Salmonella enteritidis, Salmonella typhimurium, Salmonella gallinarum, and Salmonella pullorum without affecting beneficial bacteria, in addition to showing excellent tolerance to acid, heat and desiccation. The novel bacteriophage...

12/26/13 - 20130344034 - Parovirus having a cpg-enriched genome useful for cancer therapy
A parvovirus characterized by a CpG-enriched genome, wherein the genome contains at least 2 additional CpG inserts that are not present in the wild type genome is described as well as the use of said parvovirus, e.g., a parvovirus based on parvovirus H1, LuIII, Mouse minute virus (MMV), Mouse parvovirus...

12/19/13 - 20130336932 - Novel salmonella bacteriophage and uses thereof
The present invention is directed to isolated bacteriophages having specificity and lytic activity against strains of Salmonella species, methods of using the bacteriophages, progeny and derivatives derived therefrom, to control the growth of Salmonella species in various settings (e.g., food safety, sanitation, probiotics)....

12/05/13 - 20130323209 - Novel bacteriophage and its use for preventing proliferation of pathogenic bacteria
The present invention relates to a novel phage, which is newly isolated and identified, a composition for inhibiting growth of bacteria or killing thereof comprising the same as an active ingredient, and the present invention can be diversely used as a composition for preventing or treating bacterial infectious diseases, a...

12/05/13 - 20130323210 - Infectious schmallenberg virus from cloned cdnas and uses thereof
The present invention belongs to the field of animal health and relates to a nucleic acid sequence which comprises the complete genome of an infectious Schmallenberg virus (SBV) useful for studying viremia and diseases caused by SBV in ruminants, and in the development of vaccines, therapeutics and diagnostics for the...

11/28/13 - 20130315873 - Pesticide composition for shortening the virus lethal time
The present invention is related to a pesticide composition for shortening the virus lethal time that comprises 0.01-75% of a ryanodine receptor insecticide or a diamides insecticide and 107-1012 PIB/ml of baculovirus. The pesticide composition of the present invention can effectively reduce the lethal time to the pest compared to...

11/28/13 - 20130315874 - Inhibition and dispersion of biofilms in plants with imidazole-triazole derivatives
Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including...

11/21/13 - 20130309205 - Simian adenoviruses sadv-36, -42.1, -42.2, and -44 and uses thereof
A recombinant vector comprises simian adenovirus 36, simian adenovirus 42.1, simian adenovirus 42.2 and/or simian adenovirus 44 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses one or more simian adenovirus-36, -42.1, -42.2 or -44 gene(s) is also described. Methods of using the...

11/14/13 - 20130302284 - Modulating oncolytic vsv and upregulating rae1 and nup98 with statins
Simvastatin is used to modulate VSV infection at the level of viral replication. Both lipid-lowering and pleiotropic cellular effects of simvastatin are exploited in the modulation. Simvastatin upregulates the expression of Rae1 and Nup98, therefore altering normal cellular mRNA distribution and reverting VSV's mRNA export block. Furthermore, simvastatin causes redistribution...

09/26/13 - 20130251683 - Prolonged delivery of heparin-binding growth factors from heparin-derivatized collagen
The present invention relates to a heparin-derivatized collagen matrix comprising a fragment of heparin covalently linked to a collagen scaffold, wherein the fragment of heparin has molecular weight of less than about 15 kDa, and at least one heparin-binding growth factor (HBGF) or heparin-binding adeno-associated virus (HB-AAV) or a combination...

08/15/13 - 20130209413 - Use of parvovirus for eliminating cancer stem cells (cscs)
Described is the use of a parvovirus, preferably H-1PV, for the therapeutical elimination of cancer stem cells (CSCs), preferably neuroblastoma stem cells and glioblastoma stem cells....

07/25/13 - 20130189229 - Method for protecting plants using insect-pathogenic viruses and cellulose sulfate
The invention relates to a method of protecting plants, in which plant protection agents containing insect-pathogenic viruses and cellulose sulfate are applied onto the plants....

07/11/13 - 20130177533 - Method for treating inflammation associated with amyloid deposits and brain inflammation involving activated microglia
Filamentous bacteriophage which does not display an antibody or a non-filamentous bacteriophage antigen on its surface is used to inhibit or treat brain inflammation associated with amyloid deposits and/or involving activated microglia, to inhibit the formation of amyloid deposits, and to disaggregate pre-formed amyloid deposits....

07/11/13 - 20130177534 - Plant protection agent comprising insect-pathogenic viruses, in particular baculoviruses, and cellulose sulfate
The present invention relates to a crop protection agent containing insect-pathogenic viruses, in particular baculoviruses, and cellulose sulfate and/or derivatives thereof....

06/27/13 - 20130164264 - Defective interfering virus
Cloned, i.e. defined, defective interfering (DI) influenza A virus is produced in embryonated hens eggs using a method which generates large quantities of DI virus material. Co-administration of cloned DI influenza A virus with a lethal dose of virulent influenza A virus conferred protection in mice compared to a control...

05/23/13 - 20130129685 - Stabilisation of viral particles
A method for preserving viral particles comprising: (a) providing an aqueous solution of (i) viral particles, (ii) optionally one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester...

04/11/13 - 20130089525 - Antimicrobial compositions and methods of use thereof
The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif....

03/07/13 - 20130058899 - Cancer therapy with a parvovirus combined with an hdac inhibitor
Described is a pharmaceutical composition comprising (a) a parvovirus and (b) a histone deacetylase inhibitor (HDACI) and the use of said composition for treatment of cancer, e.g., brain tumor, cervical carcinoma, or pancreatic carcinoma....

02/28/13 - 20130052165 - Methods of producing adenovirus vectors and viral preparations generated thereby
The present invention, in some embodiments thereof, relates to methods of producing adenoviruses such as pro- and anti-angiogenic adenovirus vectors and preparations generated thereby. Particularly, in some embodiments, the viral vectors comprise a heterologous pro- or anti-angiogenic gene under the transcriptional control of the murine pre-proendothelin promoter (e.g. PPE-1-3X), for...

02/21/13 - 20130045186 - Method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
Adeno-associated virus rh.10 sequences, vectors containing same, and methods of use are provided....

02/14/13 - 20130039891 - Poxviral oncolytic vectors
The present invention relates to a poxvirus comprising a defective F4L and/or I4L gene, to composition comprising such poxvirus and to the methods and use of such compositions and poxviruses for therapeutic purposes, and more particularly for the treatment of cancer....

01/24/13 - 20130022579 - Bacteriophage and antibacterial composition comprising the same
The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Salmonella typhimurium, Salmonella gallinarum, or Salmonella pullorum, a composition for the prevention or treatment of infectious diseases including salmonellosis and Salmonella food poisoning caused by Salmonella typhimurium, Fowl typhoid caused by...

01/10/13 - 20130011369 - Method for prevention and treatment of salmonella infection
The present invention relates to a composition comprising bacteriophage SP-1, the bacteriophage capable of destroying Salmonella once being infected in Salmonella, as an active ingredient, and a method for prevention and treatment of Salmonella infection using the same. Bacteriophage SP-1, the active ingredient of the composition of the present invention,...

01/10/13 - 20130011370 - Uniform field magnetization and targeting of therapeutic formulations
Systems and methods for magnetic targeting of therapeutic particles are provided. Therapeutic particles comprise one or more magnetic or magnetizable materials and at least one therapeutic agent. Therapeutic particles are specifically targeted using uniform magnetic fields capable of magnetizing magnetizable materials, and can be targeted to particular locations in the...

12/27/12 - 20120328575 - Modified oncolytic viruses
The present invention provides an isolated selected Picornavirus capable of lytically infecting or inducing apoptosis in a cell substantially in the absence of intercellular adhesion molecule-1 (ICAM-1), and methods for treating subjects....

12/27/12 - 20120328576 - Defined dose therapeutic phage
The invention provides therapeutic, defined-dose anti-bacterial phage preparations, methods to make such preparations, methods to treat bacterial infections using such preparations and methods to diagnose bacterial infections using such preparations....

12/27/12 - 20120328577 - Inhibition of biofilms in plants with imidazole derivatives
Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including...

11/15/12 - 20120288479 - Cross-linked polymer based hydrogel material compositions, methods and applications
A hydrogel material composition includes: (1) an alginate (or other cross-linking polymer) material; (2) an optional α-hydroxy carboxylate material; and (3) an iron cation material. The hydrogel material composition with or without the α-hydroxy-carboxylate material may be used in a photolithographic imaging application or a photorelease application within the context...

10/04/12 - 20120251502 - Human ebola virus species and compositions and methods thereof
Compositions and methods including and related to the Ebola Bundibugyo virus (EboBun) are provided. Compositions are provided that are operable as immunogens to elicit and immune response or protection from EboBun challenge in a subject such as a primate. Inventive methods are directed to detection and treatment of EboBun infection....

10/04/12 - 20120251503 - Methods of using chimeric coiled-coil molecule
The present application discloses a method of treating a disease that is treatable by therapeutic angiogenesis comprising administering to a needy subject an effective amount of a chimeric coiled coil molecule comprising a coiled-coil domain linked to a receptor binding domain of a ligand....

09/27/12 - 20120244126 - Engineered enzymatically active bacteriophage and methods for dispersing biofilms
The present invention is directed to engineered enzymatically active bacteriophages that are both capable of killing the bacteria by lysis and dispersing the bacterial biofilm because they have been also engineered to express biofilm-degrading enzymes, particularly dispersin B (DspB), an enzyme that hydrolyzes β-1,6-N-acetyl-D-glucosamine, a crucial adhesion molecule needed for...

09/27/12 - 20120244127 - Aav vectors expressing sec10 for treating kidney damage
A method for enhancing repair of damaged mammalian tubular epithelial cells involves delivering to the tubular epithelial cells of a subject in need thereof a composition comprising an adeno-associated virus (AAV) comprising an AAV capsid having an amino acid sequence of a selected AAV serotype, and a minigene having AAV...

09/20/12 - 20120237483 - Oncolytic virotherapy for prevention of tumor recurrence
Described is a parvovirus for preventing recurrence of a tumor, preferably a malignant brain tumor or pancreas tumor....

09/13/12 - 20120230958 - Oncolytic vaccinia virus combination cancer therapy
Embodiments of the invention are directed methods that include a thymidine kinase deficient vaccinia virus. The methods include evaluating a tumor for reperfusion after treatment with vaccinia virus and administering an anti-angiogenic agent if reperfusion is detected....

08/30/12 - 20120219528 - Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
Stable pharmaceutical compositions comprising recombinant adeno-associated virus (AAV) virions are described. The compositions provide protection against loss of recombinant AAV vector genomes and transduceability under conditions such as exposure to cycles of freezing and thawing and storage in glass or polypropylene vials. The compositions comprise recombinant AAV virions in combination...

08/23/12 - 20120213741 - Commercial scale process for production of prrsv
The present invention describes an efficient commercial scale production method for the preparation of PRRS virus....

08/23/12 - 20120213742 - Virus growing in hypoxic cell or virus vector expressing gene therein
The present invention provides a virus or a viral vector capable of expressing a gene specifically in a cell having replication ability in a hypoxic state such as a cancer stem cell and injuring the cell, and a pharmaceutical composition comprising the same. Specifically, the present invention provides a virus...

07/19/12 - 20120183508 - Gamma secretase inhibitor for treatment of herpesvirus infection
This invention relates to methods and compositions for the treatment of malignancies associated with gamma-herpesvirus infection. Specifically, the invention s relates to the use of gamma-secretase inhibitors to prevent the production of intracellular Notch1 thereby arresting the growth of the infected cells....

07/12/12 - 20120177608 - Pseudomonas aeruginosa bacteriophage(s) and uses thereof
An isolated bacteriophage MR299-2 or NH-4 deposited under NCIMB Deposit Accession Nos. 41729 and 41730, respectively, is described. The phages have lytic activity against P. aeruginosa strains, including mucoid and CF clinical isolate strains. Variant hages are also described, wherein said variants retain the phenotypic characteristics of said phage and...

07/12/12 - 20120177609 - Method for using liberated dormant bacteriophase and environmental stress to reduce infectious bacteria
A method for obtaining bacteriophages by stressing bacteria. The method involves isolating bacteria, propagating the bacteria, exposing the bacteria to at least one environmental stressing agent to induce excision of bacteriophage that are present in the bacterial genome. Multiple or individual environmental stressing agents may be applied. These liberated bacteriophages...

06/21/12 - 20120156174 - Novel bacteriophage and antibacterial composition comprising the same
The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Salmonella enteritidis, Salmonella typhimurium, Salmonella gallinarum and Salmonella pullorum, a composition for the prevention or treatment of infectious diseases including salmonellosis and Salmonella food poisoning caused by Salmonella enteritidis or Salmonella...

06/07/12 - 20120141424 - Materials and methods for the treatment of hypertension
The present invention is directed to materials and methods for the treatment of hypertension and ischemia comprising administering at least one therapeutic agent selected from the group consisting of vascular endothelial growth factor-C product and vascular endothelial growth factor-D product, and optionally, when treating hypertension, a standard of care anti-hypertensive...

06/07/12 - 20120141425 - Virus-like particle vector for delivery of pharmaceutical agents, a process for the manufacture thereof, its uses and a pharmaceutical composition
The embodiment of the invention is a virus-like particle vector, a process for the manufacture thereof, use of the virus-like particle vector and a pharmaceutical composition, which contains the virus-like particle vector. The vector is intended for the delivery of therapeutic agents into specific mammalian tissues, especially low molecular weight...

06/07/12 - 20120141426 - Reovirus for the treatment of cellular proliferative disorders
Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the...

06/07/12 - 20120141427 - Attenuated strain of myxoma virus for use as an oncolytic drug
The invention relates to the use of an attenuated vaccinal strain of Myxoma virus, in particular the SG33 strain, as an oncolytic agent....