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Drug, Bio-affecting And Body Treating Compositions > Whole Live Micro-organism, Cell, Or Virus Containing

Whole Live Micro-organism, Cell, Or Virus Containing

Whole Live Micro-organism, Cell, Or Virus Containing patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

01/04/07 - 20070003517 - Inhibitors of the jnk signal transduction pathway and methods of use
JNK-interacting protein 1 (JIP-1), an inhibitor of the JNK1 protein, and methods of treating a pathological condition or of preventing the occurrence of a pathological condition in a patient by the administration of a therapeutically effective amount of JIP-1 polypeptides, peptides, peptide mimetics, or nucleic acids are described. ...

10/19/06 - 20060233752 - Method for treating or preventing systemic inflammation in formula-fed infants
The present invention is directed to a novel method for treating or preventing systemic inflammation in a formula-fed infant. The method comprises administering a therapeutically effective amount of LGG to the infant. ...

08/31/06 - 20060193829 - Binding molecules for human factor viii and factor viii-like proteins
It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of ...

05/25/06 - 20060110360 - Methods of treating tumors using natural killer cell lines
This invention relates to a natural killer cell line termed NK-92. The invention provides a vector for transfecting a mammalian cell which includes a nucleic acid sequence encoding a cytokine that promotes the growth of NK-92. Additionally, the invention provides an NK-92 cell, or an NK-92 cell modified by transfection ...

05/25/06 - 20060110359 - Cellular delivery of natriuretic peptides
The present invention pertains to a method for treating deficits, such as neurological deficits, caused by focal or generalized edema associated with injury to the central nervous system, heart, liver, and kidney. The present invention further concerns a method for producing natriuretic peptides and pharmaceutical compositions comprising bone marrow stromal ...

05/11/06 - 20060099177 - Methods for treating hiv infected subjects
Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the absence of exogenous growth factors ...

05/04/06 - 20060093581 - Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both: methods for obtaining same; and their uses
A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture medium is replaced at a rate and for a time sufficient to obtain the human lineage committed ...

05/04/06 - 20060093580 - Tolerogenic vaccine and method
Methods and compositions are provided for treating autoimmune diseases such as diabetes, rheumatoid arthritis, inflammatory bowel disease, and other conditions involving undesired immune responses such as allergies, including food allergies, and graft-versus-host disease. In one embodiment disclosed, regulatory/suppressor T cells are selected or expanded in culture using a phospholipase D ...

04/20/06 - 20060083717 - System and method for forming a non-ablative cardiac conduction block
A system forms a cardiac conduction block at a location in a heart of a patient, generally without substantially ablating cardiac tissue. The system includes a delivery system coupled to a source of material that is substantially non-ablative with respect to cardiac tissue but that substantially interrupts and thus blocks ...

04/20/06 - 20060083716 - Composition for delivering an agent to a target cell and uses thereof
The present invention provides a composition for delivering an agent to a target cell, comprising: (a) a microorganism that has, on its cell surface, at least one exogenous molecule that binds to an antigen on the surface of a target cell; and (b) an agent. The present invention further provides ...

04/13/06 - 20060078541 - Method and formula for stem cells' stimulation, targeting release, trafficking and homing
The present invention relates to the fields of pharmacology, regenerative medicine, electro-physiology, and stem cell therapy. In a method aspect, a method of stimulating stem cell release in a mammal is provided. The method includes the step of administering a composition to the mammal, and wherein the composition comprises from ...

04/13/06 - 20060078540 - Dendritic cell nodes
The present invention features dendritic cell nodes that can be used to vaccinate subjects against pathogens and to modulate a subject's immune system to treat or prevent various diseases and conditions. ...

04/06/06 - 20060073118 - Methods of activating nkt cells
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or upregulate expression of a cell surface marker on the ...

04/06/06 - 20060073117 - Methods and compositions for controlling hair follicle stem cell fate
The present invention relates to mutant hair follicle stem cells possessing an inactive Bmpr1a receptor, wherein such mutant hair follicle stem cells proliferate and undergo self-renewal. Additionally, the present invention relates to compositions and methods for induction of hair follicle stem cell proliferation in vivo and in vitro. The present ...

04/06/06 - 20060073116 - Identification and use of high efficacy vaccine antigens which modulate antigen presenting cells
The present invention relates to the identification and use of high efficacy vaccine antigens which modulate antigen presenting cells. ...

03/30/06 - 20060067914 - Immortalized natural killer cell line
The present invention provides an immortalized natural killer cell line retaining the function and characteristics intrinsic to natural killer cells, a method for establishing the same, a method for screening for useful substances using the immortalized natural killer cell line, and a cell vaccine. By culturing natural killer cells obtained ...

03/23/06 - 20060062763 - Methods for the isolation and expansion of cord blood derived t regulatory cells
The present invention encompasses methods, and kits for the isolation and expansion of T regulatory cells having the CD45RA+ phenotype, including such cells from human umbilical cord blood. ...

03/16/06 - 20060057112 - Macrophage derived chemokine (mdc), mdc analogs, mdc inhibitor substances and uses thereof
The present invention provides purified and isolated polynucleotide sequences encoding a novel macrophage-derived C-C chemokine designated “Macrophage Derived Chemokine” (MDC), and polypeptide fragments and analogs thereof. Also provided are materials and methods for the recombinant or synthetic production of the chemokine, fragments, and analogs; and purified and isolated chemokine protein, ...

03/16/06 - 20060057111 - Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
The present invention relates to methods of treating mammals affected by, for example, a hyperproliferative disease such as cancer, by administering a tumor-targeted superantigen and a chemotherapeutic agent, whereby the administration of the tumor-targeted superantigen and chemotherapeutic agent reduce the antibody response and enhance the T cell response. The superantigen, ...

03/16/06 - 20060057110 - Antigen-presenting cells for neuroprotection and nerve regeneration
Pharmaceutical compositions and methods for preventing or inhibiting neuronal degeneration, or for promoting nerve regeneration, in the central nervous system (CNS) or peripheral nervous system (PNS), in the treatment of an injury, disorder or disease of the CNS or PNS, comprise antigen-presenting cells, preferably dendritic cells, that have been pulsed ...

03/16/06 - 20060057109 - Method of using anti-apoptotic factors in gene expression
The present invention is directed to methods of prolonging the expression of a heterologous gene (transgene) in a cell, preferably a malignant cell. This method can be used to increase the concentration of a chemotherapeutic agent in a target cellular environment. Preferably, the present invention relates to methods of inhibiting ...

03/16/06 - 20060057108 - Use of urea-adjuvated polypeptides for diagnosis, prophylaxis and treatment
The invention relates to a method for infiltration of polypeptides in cells. The invention further relates to the use of the cells and urea-adjuvated polypeptides for the diagnosis, treatment or prevention of diseases. The invention further relates to the detection of polypeptide-specific immune cells. ...

03/09/06 - 20060051321 - Biological compositions and methods for treatment of testicular cancer
The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthfull benefit in a subject inflicted with testicular cancer. The biological compositions can be used to retard the growth of testicular cancer cells and/or prolonging the time of survival of the subject. The ...

02/16/06 - 20060034802 - Procedure for the large-scale t-lymphocytes culture in a homogeneous system
The present invention refers to a procedure for the large-scale amplification of human lymphocytic cell lines for therapeutic use, consisting of a homogeneous culture system. The claimed invention also refers to the production of therapeutic doses of lymphocytic cells cultured homogeneously. ...

02/09/06 - 20060029575 - Compositions and methods for producing and using homogenous neuronal cell transplants
Methods of treating individuals suspected of suffering from diseases, conditions or disorders of the Central Nervous System which comprise implanting stable, homogeneous post-mitotic human neurons into the individual's brain are disclosed. Methods of treating individuals suspected of suffering from injuries, diseases, conditions or disorders characterized by nerve damage which comprise ...

02/09/06 - 20060029574 - Biomarkers for diagnosis, prognosis, monitoring, and treatment decisions for drug resistance and sensitivity
The present invention provides methods and compositions for identifying cancer cells that are either sensitive or resistant to a particular anti-cancer therapy. Accordingly, the present invention allows for more accurate diagnosis, prognosis, and monitoring of a subject's condition. Furthermore, the ability to assess a subject's resistance or sensitivity to a ...

01/26/06 - 20060018878 - Dual antigen specific t cells with trafficking ability
The present invention is directed to mammalian T cells and methods for using these T cells. More specifically, the invention relates to viral specific T cells that express an endogenous viral antigen receptor, a chimeric anti-tumor receptor and the chemokine receptor CCR7. These T cells are a source of effector ...

01/26/06 - 20060018877 - Intradermal delivery of vacccines and therapeutic agents
The present invention relates to methods and devices for administration of vaccines and therapeutic agents into the intradermal layer of the skin. The methods of the present invention elicit increased humoral and/or cellular response as compared to conventional vaccine delivery methods, e.g., intramuscular route. Furthermore, the methods of the present ...

10/13/05 - 20050226846 - Nucleic acid vaccine compositions having a mammalian cd80/cd86 gene promoter driving antigen expression
Polynucleotides encoding at least one immunizing antigen whose expression is controlled by a promoter derived from a gene encoding a co-stimulatory molecule are provided. The polynucleotides may also encode adjuvants. Compositions comprising at least one immunizing agent and at least one cytokine that enhance dendritic cell stimulation and/or survival are ...



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