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Drug, Bio-affecting And Body Treating Compositions > In Vivo Diagnosis Or In Vivo Testing > Magnetic Imaging Agent (e.g., Nmr, Mri, Mrs, Etc.)

Magnetic Imaging Agent (e.g., Nmr, Mri, Mrs, Etc.)

Magnetic Imaging Agent (e.g., Nmr, Mri, Mrs, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

07/05/07 - 20070154394 - Diagnostic agents for pancreatic exocrine function
Y1 is a 13C-labeled alanine molecule optionally having a protecting group. ...

06/14/07 - 20070134159 - Quantitation of sample properties using contrast enhancement from saturation transfer
The manipulation of RF irradiation to a subject in which a CEST agent has been administered is employed to determine a biological parameter in vivo in conjunction with an MRI imaging process. The exchange rate of the CEST agent is determined through RF manipulation which in turn enables the determination ...

06/07/07 - 20070128114 - Method for monitoring protein translation
Disclosed is a method for monitoring early treatment response of a cancer treatment comprising measuring by magnetic resonance spectroscopy (MRS), for example, proton MRS, the amount of Choline present in the tissue adjoining or surrounding the cancerous tissue before and after treatment; the treatment comprises administration of an angiogenesis inhibitor, ...

05/17/07 - 20070110669 - Methods for in vivo evaluation of pulmonary physiology and/or function using nmr signals of polarized 129xe
In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of ...

05/10/07 - 20070104648 - Compositions, methods of preparing amino acids, and nuclear magnetic resonance spectroscopy
The present invention relates to amino acids, complexes, and compounds comprising deuterium and tritium isotopes preferably alpha deuterated amino acids, polypeptides, antibodies, derivatives and saccharide-amino acid complexes and conjugates. In some embodiments, the invention relates to methods of using compounds comprising deuterium for imaging biochemical concentrations and distributions in mammalian ...

04/19/07 - 20070086948 - Tissue metabolic stress monitoring
Various pathophysiological states are determined by evaluating the rate of 17O-containing water production oxygen using proton MRI. The method can be used to identify viable but threatened myocardium, injured by viable muscle, penumbra tissue in a stroke patient, and the like. ...

01/18/07 - 20070014727 - Contrast media for nuclear spin tomography with use of the overhauser effect
The invention relates to contrast media for nuclear spin tomography (or else magnetic resonance tomography, MRT) with use of the Overhauser effect, which are suitable for transferring the magnetic orientation of electron spins to adjacent proton spins. ...

11/23/06 - 20060263300 - Apparatus for producing hyperpolarized noble gas, and nuclear magnetic resonance spectrometer and magnetic resonance imager which use hyperpolarized noble gases
This apparatus for producing a hyperpolarized noble gas includes: a hyperpolarized noble gas generating cell in which a noble gas is subjected to an optical pumping in the presence of an alkali metal so as to generate a hyperpolarized noble gas; and a very fine capillary tube having an inside ...

11/09/06 - 20060251581 - Method for treatment of uterine fibroid tumors
Various injectable or insertable uterine fibroid treatment formulations are provided, which comprise a uterine fibroid treatment agent in an amount effective to cause shrinkage or elimination of uterine fibroids. The injectable or insertable formulations are typically solids, semi-solids or high-viscosity fluids. Other aspects of the invention are directed to systems ...

10/26/06 - 20060239920 - Imaging methods for early detection of brain tumors following embryonic stem cell implants
Non-invasive imaging methods and minimally invasive sensing methods are used for assessing the viability of cells implanted in the central nervous system for therapeutic purposes and for detecting the transformation of such cells, including embryonic stem cells, into brain tumors. In particular, the present invention provides an imaging means for ...

10/26/06 - 20060239919 - Mr coronary angiography with a fluorinated nanoparticle contrast agent at 1.5 t
Disclosed herein is a medical imaging technique that uses a fluorinated nanoparticle contrast agent for imaging of an interior portion of a body. The fluorinated nanoparticles preferably comprise nontargeted intravascular fluorocarbon or perfluorocarbon nanoparticles. The interior body portion may be a patient's vasculature, and the medical imaging is preferably noninvasive ...

10/26/06 - 20060239918 - Method for forecasting the contrast medium flow in a living body
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10/26/06 - 20060239917 - Method for forecasting the contrast medium flow in a living body
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10/26/06 - 20060239916 - Use of cyanine dyes for the diagnosis of proliferative diseases
The present invention concerns the use of the cyanine dye SF64 for the diagnosis of proliferative diseases upon administration of less than 5 mg/kg body weight. ...

10/26/06 - 20060239915 - Labeled macrophage scavenger receptor antagonists for imaging cardiovascular diseases
The present invention is in the field of diagnostic imaging. In one aspect, the invention relates to novel imaging agents comprising synthetic macrophage scavenger receptor A antagonists, said imaging agents being useful in the diagnostic imaging of cardiovascular disease. Also claimed in the present invention is a pharmaceutical composition comprising ...

10/05/06 - 20060222591 - Method for monitoring early treatment response
Disclosed is a method for monitoring early treatment response of a cancer treatment comprising measuring by magnetic resonance spectroscopy (MRS), for example, proton MRS, the amount of Choline present in the endomembranes of the cancerous tissue before and after treatment; the treatment comprises administration of a cytotoxic therapy, whereby a ...

08/10/06 - 20060177379 - Composition comprising an agent providing a signal, an implant material and a drug
The present invention relates to compositions or combinations of materials for non-degradable and degradable implantable medical devices with regard to the setup of their signal generating properties and control of their therapeutic effectiveness, as well as to a method for the control of degradation of degradable or partially degradable medical ...

08/10/06 - 20060177378 - Method for monitoring early treatment response
Disclosed is a method for monitoring early treatment response of a cancer treatment comprising measuring by magnetic resonance spectroscopy (MRS), for example, proton MRS, the amount of Choline present in the tissue adjoining or surrounding the cancerous tissue before and after treatment; the treatment comprises administration of an angiogenesis inhibitor, ...

08/10/06 - 20060177377 - Method for monitoring early treatment response
Disclosed is a method for monitoring early treatment response of a cancer treatment comprising measuring by magnetic resonance spectroscopy (MRS), for example, proton MRS, the amount of Choline present in the tissue adjoining or surrounding the cancerous tissue before and after treatment; the treatment comprises administration of an angiogenesis inhibitor, ...

08/10/06 - 20060177376 - Stabilized and chemically functionalized nanoparticles
Dendronization of nano-scale surfaces with focal point reactive dendrons to produce stabilized chemically functionalized nano-particles having quantum dot dimensions. ...

08/03/06 - 20060171892 - Conjugates for medical imaging comprising carrier, targetting moiety and a contrast agent
This invention relates to the delivery of agents to the body. One particular class of such agents are contrast agents useful in medical imaging techniques. The agents may be metals useful as contrast agents in magnetic resonance imaging (MRI), or in nuclear imaging, including positron emission tomography (PET), or as ...

08/03/06 - 20060171891 - Nmr-based methods for detecting ligands, where the ligand or target are hyperpolarized and the nmr-spectrum is compared with a reference spectrum of the ligand or target
The invention relates to NMR-based methods comprising hyperpolarised ligands or targets for use in NMR-based assays. ...

07/13/06 - 20060153774 - Contrast agent coated medical device
A magnetically opaque medical device is disclosed wherein a contrast agent is incorporated into the actual device. The medical device is generally comprised of a base material forming the structure of the device and a contrast agent, such as tocopherol and tocopherol derivative solutions or suspensions, gadolinium, or nickel sulfate ...

07/13/06 - 20060153773 - Contrast medium for mri
Disclosed is an MRI contrast agent which enables direct detection and imaging of exfoliated vascular endothelial sites. The MRI contrast agent comprises an imaging unit which contains an unpaired electron-carrying atom and/or molecule and is capable of amplifying or reducing MRI signals, and a detection unit which is bonded to ...

06/15/06 - 20060127315 - Methods of treating humans undergoing injection of a contrast agent
A human undergoing an injection of a contrast agent is treated by the administration of an iron chelator. Administration of the iron chelator can essentially prevent the onset of acute renal failure in a human. Administration of the iron chelator can reduce the severity of the acute renal failure and/or ...

06/15/06 - 20060127314 - Method and arrangement for producing contrast agent for magnetic resonance imaging
The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and ...

06/15/06 - 20060127313 - Method and apparatus for producing contrast agents for magnetic resonance imaging
The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and ...

05/18/06 - 20060104906 - Method and apparatus for producing contrast agents for magnetic resonance imaging
The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and ...

05/11/06 - 20060099145 - Pharmaceutical preparation containing magnetic vesicular particles, manufacturing method thereof and diagnostic therapeutic system
wherein R represents an average grain size of the magnetic vesicular particles and r represents an average particle size of magnetic microparticles included in the magnetic vesicular particles. ...

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04/20/06 - 20060083687 - Method and system of obtaining improved data in perfusion measurements
A method of deriving blood perfusion indices for a region of interest (ROI) of a subject, comprising the steps of administering a contrast agent to the subject during a dynamic imaging scan, converting signal intensity data from raw images of the scan into contrast agent concentration data, deriving parameters from ...

03/23/06 - 20060062731 - Dual gradient echo pulse sequence using interleaved spiral-out spiral-in k-space trajectories
Measurements of functional, hemographic, and blood flow parameters use a multiple echo or spin echo gradient pulse sequence whereby an early echo is acquired near the beginning of the pulse sequence which avoids saturation effects and a later echo near the end of the pulse sequence which can provide information ...

02/16/06 - 20060034765 - Mri method for measuring tumor hemodynamic parameters in the presence of contrast agent extravasation
One or two sets of time course NMR data are acquired using an EPI pulse sequence in which either or both gradient recalled echo NMR signals and spin-echo NMR signals are acquired after bolus injection of a contrast agent. T2* relaxation rates for GE and T2 relaxation rates for SE ...

02/02/06 - 20060024235 - Stabilised superparamagnetic particles
The invention relates to stabilized superparamagnetic particles which consist of superparamagnetic single domain particles and aggregations of superparamagnetic particles which are stabilized with aliphatic dicarboxylic or polycarboxylic acids and which contain charged ions of chemical elements on the surface of the small superparamagnetic single-domain particles and, optionally, an additional tissue ...

01/26/06 - 20060018835 - Nanoparticles with inorganic core and methods of using them
An aspect of the invention includes a nanoparticle including a substantially monodisperse inorganic core with a surface and a coating substantially covering the surface of the substantially monodisperse inorganic core, wherein the coating includes of at least coating structure I, II, or III wherein the nanoparticle is substantially non-agglomerated and ...

11/10/05 - 20050249667 - Process for treating a biological organism
A process for treating cells within a biological organism in which sonic energy is focused on cells within a biological organism while the frequency and/or the power level of such energy is varied. In addition there is provided a process for synergistically combining sonic energy and other forms of energy, ...

10/20/05 - 20050232864 - Method for phenotyping using nmr spectroscopy
The invention relates to methods for phenotyping by determining protein activity in vivo using at least one probe compound and enhancing the nuclear polarisation of NMR active nuclei present in the probe compound (hereinafter termed “hyperpolarisation”) prior to NMR analysis. ...

07/28/05 - 20050163713 - Methods and devices for measuring diffusion by magnetic resonance imaging
The present invention relates generally to the field of magnetic resonance imaging and, more particularly, to devices and methods used in the observation of the diffusion of molecules across a permeable membrane using magnetic resonance techniques. A typical embodiment of the invention is a method of observing the diffusion of ...

07/14/05 - 20050152840 - Process
ii) introducing said solution in droplet form into a chamber containing hydrogen gas (H2) enriched in para-hydrogen (p-1H2) and/or ortho-deuterium (o-2H2) whereby to hydrogenate said substrate to form a hydrogenated imaging agent; iii) optionally subjecting said hydrogenated imaging agent to a magnetic field having a field strength below earth's ambient ...



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