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Drug, Bio-affecting And Body Treating Compositions > In Vivo Diagnosis Or In Vivo Testing In Vivo Diagnosis Or In Vivo TestingIn Vivo Diagnosis Or In Vivo Testing patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.08/09/07 - 20070183975 - Polypeptide absorbable into digestive organs A polypeptide absorbable into digestive organs, which is linked with a bioactive polypeptide, and assists absorption of the bioactive polypeptide into digestive organs when it is orally taken; a fusion polypeptide comprising the polypeptide absorbable into digestive organs and the bioactive polypeptide; and an oral composition comprising the fusion polypeptide ... 08/09/07 - 20070183974 - Method and apparatus for production of a skin graft and the graft produced thereby A micro-organ structure comprising at least two micro-organ portions formed from a tissue, in which said at least two micro-organs are linked one to the other by means of a junction formed from said tissue of which the micro-organs were formed therefrom. ... 08/02/07 - 20070178046 - System for correlating odors and tastes to objective elements A kit containing a plurality of scent/flavor samples and taste samples contained in individual vessels. Methods of teaching an understanding of taste, smelling with the nose, smelling with the mouth, and the concept of “flavor,” is facilitated. Numerous possibilities of combining scents with tastes, thus enabling a person to explore ... 07/12/07 - 20070160536 - Tumor activated prodrugs The instant invention provides compositions comprising a prodrug, the prodrug comprising a therapeutically active drug; and a peptide selected from the group consisting of the sequences: Ser-Ser-Lys-Tyr-Gln (SEQ ID NO:1);Gly-Lys-Ser-Gln-Tyr-Gln (SEQ ID NO:2); and Gly-Ser-Ala-Lys-Tyr-Gln (SEQ ID NO:3) wherein the peptide is linked to the therapeutically active drug to inhibit ... 06/07/07 - 20070128113 - Methods for delivering mbd peptide-linked agent into cells under conditions of cellular stress The present invention is related to methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes. ... 05/31/07 - 20070122343 - Non-invasive assay for the assessment of functioning and/or structure of the gut The present invention relates to a diagnostic method for assessing the functioning and/or structural integrity of the gut in animal subjects. The method of the present invention is predicated on assessing the absorption and/or metabolism of one or more test sugars or functional equivalents such as phosphorylated sugars, oligopeptides or ... 04/26/07 - 20070092447 - Contrast agent for combined modality imaging and methods and systems thereof A combined modality imaging system includes a first imaging device of a first modality and a second imaging device of a second modality that is different from the first modality is provided. The first and the second imaging devices are both adapted to interact with a contrast agent. The contrast ... 04/26/07 - 20070092446 - Patient selection method for assisting weight loss A method is provided for identifying a patient as being suitable for implantation of a weight-loss assist device. The method includes identifying the patient as being generally suitable for the implantation and subsequently, measuring a value associated with the patient. Responsively to determining that the value is beyond a threshold ... 04/26/07 - 20070092445 - Assessing ovarian reserve Methods for assessing the ovarian reserve of a female subject may include (a) testing the concentration of follicle stimulating hormone (FSH) in urine samples obtained from the subject, the samples being obtained on at least two different days during a first menstrual cycle in the subject; (b) testing the concentration ... 04/19/07 - 20070086945 - Preparations for diagnosis of pancreatic exocrine function A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance is carried by a carrier and released from ... 04/12/07 - 20070081944 - Iontophoresis apparatus and method for the diagnosis of tuberculosis An iontophoresis device includes an active electrode assembly including an active electrode element and at least one active agent reservoir. Active agents include one or more polypeptides, or fusion polypeptides, having antigenic determinants derived from or related to M. tuberculosis antigens and suitable for detection of tuberculosis. ... 04/12/07 - 20070081943 - Alpha 4 beta 2 delta gaba-a receptors as a strategy for pms and alcoholism The present invention is directed to a screening mechanism for identifying members of the general population at increased risk for alcoholism and premenstrual syndrome. The screening mechanisms may be used to measure the expression of the α4β2δ GABAA receptors, in order to identify members of the general population as having ... 04/05/07 - 20070077202 - Histostain composition for endoscope The invention relates to a histostain composition for endoscope containing one or more members selected from colors derived from Monascus. The stain composition is a staining agent which sharpens the shapes of digestive tract lumen surfaces and the like with a light in the visible wavelength range, having a function ... 04/05/07 - 20070077201 - Stem cell expansion and uses The invention relates to methods to manipulate stem cells in vivo and in vitro to treat, e.g., a conditions where cell or tissue repiar is needed. ... 04/05/07 - 20070077200 - Method and system for controlled maintenance of hypoxia for therapeutic or diagnostic purposes Embodiments of the present invention relate to a system, device, and method for automatically inducing, maintaining, or controlling hypoxia in a patient. Specifically, embodiments of the present invention relate to delivering a hypoxic gas mixture to a patient, monitoring at least one physiological parameter of the patient, and automatically controlling ... 03/29/07 - 20070071680 - Methods and compositions for preparing consumables with optical shifting properties Ingestible compositions comprising a chromic change agent together with methods of making and using them are provided. The chromic change agent alternatively may be associated with the ingestible, such as a packaging material for the ingestible. In response to a triggering event, physical or chemical, the chromic change agent changes ... 03/29/07 - 20070071679 - Methylamine risks and treatment of hyperactivity, depression, and alcoholism with epinephrine-n-quinolines Results of animal experiments proving a relationship between ontogenetically early sleep-wake behaviour and neurobehavioural disorders during later life indicate examination of ontogenetically early sleep-wake behaviour in human beings. With drugs with N-adrenaline moiety and with drugs with PNMT-inhibiting activity, in addition with effects on adrenergic beta and alpha-1 receptors, and ... 03/22/07 - 20070065363 - Quantifying hemodynamic response to drug therapy using implantable sensor Systems and methods provide for assessing a patient's hemodynamic response to a drug therapy. A patient's hemodynamic response to a drug therapy is monitored using sensor data acquired using one or more sensors. The patient's hemodynamic response to the drug therapy is quantified, such as by quantifying a patient's sensitivity ... 03/15/07 - 20070059242 - Methods to identify therapeutic agents As illustrated herein, cholesterol is oxidized when it is present in atherosclerotic plaques. This reaction generates cholesterol oxidation or ozonation products that can act as chemotactic attractants of macrophages, can promote differentiation of monocytes into macrophages and can increase expression of E-selectin and Class A scavenger receptor (SR-A). The present ... 03/08/07 - 20070053839 - Directing cells to target tissues organs The invention provides for methods of directing cells to a damaged tissue or organ in an individual, and further provides for methods of monitoring such cells in the individual. The invention also provides compositions for tagging cells such that the cells can be directed to the damaged tissue or organ. ... 03/01/07 - 20070048224 - Method and apparatus to sense hydration level of a person A hydration sensor or sensing element configured to measure the hydration level of a user is disclosed. The sensing element can include a water-permeable material positioned in between two water-impermeable material. The sensing element can be coupled to a bottle of fluid, or a carrier with a timer. The sensing ... 02/15/07 - 20070036721 - Methods and compositions for in vivo inflammation monitoring Disclosed are methods and materials for detecting inflammation using in vivo and in vitro monitoring, as well as methods of reducing inflammation. Also disclosed are composition related to in vivo monitoring of inflammation, as well as transgenic animals and cell lines useful for such. ... 02/08/07 - 20070031335 - Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers Novel genes designated and set forth in FIG. 2 and their respective encoded proteins, and variants thereof, are described wherein a gene of the invention exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers such as those listed in Table I. Consequently, of gene ... 01/25/07 - 20070020181 - Non-invasive measurement of analytes This invention provides devices, compositions and methods for determining the concentration of one or more metabolites or analytes in a biological sample, including cells, tissues, organs, organisms, and biological fluids. In particular, this invention provides materials, apparatuses, and methods for several non-invasive techniques for the determination of in vivo blood ... 01/25/07 - 20070020180 - Method for determining the impact of a multicomponent natural product mixture on the biological profile of a disease within a group of living systems and the developement and quality control of natural product based medicine The present invention provides a method for determining the impact of a multicomponent natural product mixture on the biological profile of a disease comprising the steps of: (a) determining a biological profile of the disease by comparing the biological profile of a group of living systems with symptoms of the ... 01/18/07 - 20070014726 - Oxidation-resistant indicator macromolecule In one aspect, the present invention relates to an implantable device for detecting the presence or concentration of an analyte in an aqueous environment in vivo. The device includes a macromolecule that comprises a copolymer of: a) one or more indicator component monomers which individually are not sufficiently water soluble ... 01/11/07 - 20070009438 - Method for diagnosing diabetes type 2 using standardized mixed meal and calculated index values The present invention provides methods and materials for diagnosing a metabolic disorder comprising measuring insulin and HISS action or alternatively HISS levels, first in a fasting state and again, following consumption of a mixed standard meal. The metabolic disorders diagnosed using the disclosed methods and materials include insulin resistance, pre-diabetes ... 01/04/07 - 20070003481 - Method and composition to individualize levodopa/carbidopa therapy using a breath test The present invention relates, generally to a method of determining and assessing L-3,4-dihydroxyphenylalanine (a.k.a., Levodopa; L-dopa; or LD) metabolic capacity in an individual mammalian subject via a breath assay, by determining the relative amount of 13CO2 exhaled by the subject upon intravenous or oral administration of a 13C-labeled substrate, such ... 12/14/06 - 20060280683 - Method of identifying inhibitors of gadd45 polypeptide activity, and inhibitors of such activity The present invention is directed to novel methods for assaying for modulators of GADD45 polypeptide activity. The invention also provides means to sensitize a proliferating cell to a DNA base-damaging agent by administration of novel inhibitors of GADD45 polypeptide activity. The invention further provides polypeptides which interfere with the ability ... 12/14/06 - 20060280682 - Monitoring two dimensions of diabetes pathogenesis seperately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development Provided are methods for determining concurrently with a simple, minimally invasive test, the adequacy of pancreatic beta-cell compensation and/or the presence of tissue insulin resistance in a subject human or an experimental animal. The methods allow for the determination of a subject's or experimental animal's susceptibility to developing type 2 ... 12/14/06 - 20060280681 - Food for testing life style-related diseases It is intended to provide a food for testing life style-related diseases which is in the form of a food easy to ingest, differing from the existing medicines such as Trelan G, and makes it possible to simultaneously and easily perform a glucose tolerance test and examine oral glucose tolerance, ... 11/23/06 - 20060263297 - Ophthalmic measuring method and apparatus A CCD camera captures an image of the lachrymal fluid layer in a prescribed position of a subject's eye to which a target substance is administered. Images are selected from a plurality of images captured, and the positions of the target substance in the selected images and the capturing times ... 11/23/06 - 20060263296 - Diagnostic kit for the measurement of glucose metabolism, method of use, and method for the manufacture thereof The present invention includes a kit for use in the performance of a 13CO2 breath test of glucose metabolism which has quality controlled labeled sugar in a first container and unlabeled sugar in a second container, methods of use and methods of manufacture thereof. ... 10/12/06 - 20060228301 - Methods and compositions for determining targeted drug sensitivity and resistance in a cancer subject Diagnostic and therapeutic methods of cancer treatment and prevention using metabolic profiling compounds that contain [1,2-13C2]-D-glucose, and kits for using such metabolic profiling compounds. ... 09/14/06 - 20060204439 - Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol The invention relates to techniques for measuring and comparing relative molecular flux rates of different biological molecules by administering isotope-labeled water to one or more tissues or individuals and comparing the molecular flux rates of two or more biological molecules, including biological molecules in different chemical classes. The methods find ... 09/14/06 - 20060204438 - Water soluble iron oxide nanoparticles and a method of its preparation This invention relates to water soluble iron oxide nanoparticles and a method of its preparation. More specifically, this invention relates to a method of manufacturing water soluble iron oxide nanoparticles uniform in size by coating polyvinylpyrolidone, a biocompatible polymer that can be intravenously administered via thermal decomposition, on the surface ... 09/07/06 - 20060198787 - Biomarkers for predicting liver fibrosis treatment efficacy The invention relates to methods for predicting or determining the efficacy of certain medical treatments, especially treatments for liver fibrosis. The methods of the invention include measuring interferon-induced ligands prior to initiating treatment and at some time following the initiation of treatment to predict the clinical outcome of the treatment. ... 08/24/06 - 20060188444 - Method for monitoring patient or subject compliance with medical prescriptions, and formulation for use in the method (iv) confirming the ingestion of the prescribed biologically active agent based on the ratio of the carbon isotope-labeled CO2 relative to 12CO2. ... 08/24/06 - 20060188443 - Diagnostic composition for diabetes type-2 and impaired glucose tolerance, and methods of use A solid oral diagnostic test meal is provided that contains a polysaccharide, wherein the oral diagnostic test meal provides a medically controlled quantity of glycemic carbohydrate after being ingested by a vertebrate subject. In addition, methods and kits are provided for using the diagnostic test meal to monitor postprandial glucose ... 08/10/06 - 20060177375 - Method for characterizing the efficacy of an agent targeting a primary cystic fibrosis defect Generally, the method for characterizing the efficacy of an agent targeting a primary cystic fibrosis defect comprises measuring a change in the status of lung infection in a sample population of subjects administered the agent in comparison to a control sample population of subjects; wherein the subjects in the sample ... 08/03/06 - 20060171889 - Irrigating fluid A surgical irrigating fluid composition, especially for endoscopic surgery, is provided comprising a rinsing fluid and nitrous oxide added as a marker to the rinsing fluid in an amount which is detectable in the expired breath from a mammal, especially man, that is subjected to the surgery. ... 08/03/06 - 20060171888 - Medical device and method for diagnostic sensing Devices are provided for use in medical diagnostics which include a substrate, a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening, at least one diagnostic substance contained in each reservoir, and at least one non-degradable barrier layer covering each reservoir opening, the barrier ... 08/03/06 - 20060171887 - Method for the diagnosis of helicobacter pylori infection and diagnostic kit for performing the method The method for the diagnosis of Helicobacter pylori infection by the oral administration of defined amounts of 13C-labeled urea together with a sufficient amount of an acid bringing down the pH of the solution and thereafter examining the 13C content in the urea breast test (13C-UBT), is improved in that ... 08/03/06 - 20060171886 - Method for characterizing the oxidative stress protective capacity of an antioxidative substance A method for characterizing an oxidative stress protective capacity of an antioxidative substance includes assigning a first score indicative of an oxidative stress protective capacity of a first antioxidative substance. The first score is based on the performance of the first antioxidative substance in a first antioxidative efficacy test relative ... 07/27/06 - 20060165594 - Preparation of m(co)3-complexes by solid phase techniques via metal assisted cleavage from the solid support The present invention relates to a process for generating a water soluble metal complexed agent, comprising contacting a solid phase bound organic conjugate represented by the formula I with [M(H2O)3(CO)3]n+, under suitable conditions to cause the formation of a coordinate bond between [M(H2O)3(CO)3]n+ and the tertiary amine nitrogen atom of ... 07/20/06 - 20060159621 - Method of detecting myocardial dysfunction in patients having a history of asthma or bronchospasm This invention is directed to myocardial imaging of human patients having a history of asthma or bronchospasm. In particular, the present invention uses binodenoson as a pharmacological stressor in conjunction with any one of several noninvasive and invasive diagnostic procedures available. For example, intravenous administration may be used in conjunction ... 07/13/06 - 20060153771 - Preparations for measuring gastric emptying ability Preparations whereby reduction or acceleration of the gastric emptying rate can be noninvasively evaluated: and a method of evaluating the gastric emptying rate by using these preparations. Thus, reduction or acceleration of the gastric emptying rate can be safely and conveniently examined. Namely, theses preparations are useful in objectively diagnosing ... 07/06/06 - 20060147376 - Controllably degradable polymeric biomolecule or drug carrier and method of synthesizing said carrier The present invention provides a controllably degradable cationic polymer for delivery of biomolecules (nucleic acids, peptides, etc.), drugs, molecules used in medical imaging applications, sensitizing agents used in cancer treatments, and molecules used in tissue engineering. The present invention also provides a method for synthesizing the polymer according to the ... 06/29/06 - 20060140861 - Method for diagnosing lactose intolerance and diagnostic kit for performing the method The method for diagnosing lactose intolerance in patients by the oral administration of defined amounts of lactose, followed by assaying metabolites of lactose, is performed in a way where the lactose administered contains 99% 13-labeled lactose, preferably from 5 to 30 mg, and after the administration of the 13C-lactose, the ... 06/29/06 - 20060140860 - Computational knowledge model to discover molecular causes and treatment of diabetes mellitus In one aspect, the invention comprises a method of developing an immunosuppressant drug with reduced propensity to induce type II diabetes mellitus symptoms by assaying candidate molecular entities for binding preferentially to leukocyte isoform calcineurin and less preferentially to muscle cell isoform calcineurin. In another aspect, the invention comprises a ... 06/22/06 - 20060133999 - Method for the diagnosis of helicobacter pylori infection, and a diagnostic kit for performing the method d) determining the 13C content of the blood samples by isotope ratio mass spectrometry (IRMS), and deducing the presence of Helicobacter pylori from the increase of the 13C values. ... 06/22/06 - 20060133998 - Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled amides using metal amides and photo-induced free radical carbonylation Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided. ... 06/22/06 - 20060133997 - A method of demonstrating draining activity of a cosmetic and/or dermocosmetic treatment on the superficial dermis and/or the epidermis The present invention concerns a method of demonstrating the draining activity of a cosmetic and/or dermocosmetic treatment, said method comprising: prior to the treatment, acquiring at least one first datum representative of the water content in the superficial dermis and/or in the epidermis, using an MRI imaging technique having high ... 06/22/06 - 20060133996 - Method and apparatus for determining effectiveness of sunscreens and other skin preparations in shielding human skin from uva radiation The present invention provides a method and apparatus for measuring the effectiveness of a sunscreen composition or other skin preparation in reducing the exposure of human skin to UVA radiation, wherein differential electron spin resonance spectroscopy is used to quantify the extent of UVA-induced ascorbate or other measurable radical production ... 06/08/06 - 20060120961 - Glycan analysis using deuterated glucose Novel methods and apparatuses are provided for use in identifying glucose metabolic products and determining metabolic flux by administering D7-glucose to a subject. ... 06/01/06 - 20060115430 - Calcium challenge test for detecting calcium homeostasis disorders The invention provides simple methods for detecting disorders of a subject's calcium homeostasis. The methods include administering a calcium salt to the subject and observing the effect of this dose of calcium on calcium levels in the subject's bodily fluids and/or tissues. The methods are useful to detect certain calcium ... 06/01/06 - 20060115429 - Biological systems analysis Disclosed are methods for the practice of systems pharmacology, systems toxicology, and systems pathology using patterns, such as images, reflective of the biological state of subjects such as humans or experimental mammals. The patterns are generated from data obtained from one or more samples from one or more subjects by ... 05/25/06 - 20060110325 - Serotonin and catecholamine segment optimization technology Methods of using amino acid precursors of the serotonin and catecholamine neurotransmitter systems and laboratory urinary assay of serotonin and catecholamine neurotransmitter levels for optimal treatment of neurotransmitter dysfunction and dysfunction of systems regulated or controlled by the serotonin and/or catecholamine neurotransmitter systems. The methods may also include determining a ... 05/18/06 - 20060104902 - Method of preselection patients for anti-vegf, anti-hif-1 or anti-thioredoxin therapy The present invention generally relates to methods of preselecting patients for treatment with an anti-VEGF therapy, anti-HIF-1 therapy or anti-thioredoxin therapy. Aspects of the invention combine methods of dynamic contrast enhanced-MRI and diffusion weighted-MRI for the detection of tumor histology. The methodology disclosed herein detects tissue blood volume, tumor vascularity, ... 05/18/06 - 20060104901 - Preventing or treating epithelial tissue damage or hair loss The present invention pertains to a method for preventing and/or treating epithelial tissue damage, such as is effected by inflammatory reactions, ageing or cancer and/or to prevent and/or treat hair loss. In particular, the present invention relates to substances and/or compositions modifying, in particular blocking endogenous CD1d function. According to ... 04/13/06 - 20060078497 - Health management and monitoring with and without weight loss Health management and monitoring predicated on an intermittent calorie restricted health management paradigm is provided. In an illustrative implementation, an intermittent calorie restricted health management program is provided to a participating health management subject so improve the health state of the participating subject (e.g., impact disease states in the health ... 04/06/06 - 20060073098 - Irrigating solution for neurosurgical procedures Saline is harmful to neuronal tissue as an irrigating solution during neurosurgical procedures. An irrigating solution to replace the use of saline during surgical procedure is provided. The irrigating solution includes polypeptides, magnesium, insulin and ATP in artificial CSF. ... 04/06/06 - 20060073097 - Method and index for diagnosing insulin resistance The invention provides a method for the determination on of insulin sensitivity, insulin resistance, and non-insulin dependent Diabetes mellitus based on oral glucose tolerance test data and lipid ratios from reference populations that define an insulin resistance index he invention also provides m for using the IR index to determine ... 03/30/06 - 20060067887 - Scoring estrogen and progesterone receptors expression based on image analysis A method of scoring Oestrogen and Progesterone Receptors expression (ER and PR) from histological images determines the percentage of brown image blob area in total blob area and derives percentage thresholds to quantify scoring. Brown blob area proportion is then compared with the thresholds to provide a first contribution to ... 03/23/06 - 20060062730 - Method for measuring skin absorbability A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the ... 03/16/06 - 20060057068 - Ca ix-specific inhibitors Therapeutic methods for inhibiting the growth of preneoplastic/neoplastic vertebrate cells that abnormally express MN protein are disclosed. Screening assays are provided for identifying compounds, preferably organic compounds, preferably aromatic and heterocylic sulfonamides, which inhibit the enzymatic activity of MN/CA IX and that are useful for treating patients with preneoplastic/neoplastic disease. ... 03/16/06 - 20060057067 - Lymph-like composition and method to prevent and treat central nervous system injuries The existence of the cerebrospinal fluid and the intracranial pressure contribute the susceptibility of the CNS to injuries. A lymph-like composition and method for treating brain and spinal cord injuries are provided. The lymph-like composition comprises Polypeptides, Insulin, Mg+ and ATP in an artificial cerebrospinal fluid. The method includes: a). ... 03/16/06 - 20060057066 - Reagent sets and gene signatures for renal tubule injury The invention discloses reagent sets and gene signatures for predicting onset of renal tubule injury in a subject. The invention also provides a necessary set of 186 genes useful for generating signatures of varying size and performance capable of predicting onset of renal tubule injury. The invention also provides methods, ... 03/16/06 - 20060057065 - Composition and method to prevent and treat brain and spinal cord injuries The cerebrospinal fluid (CSF) contains low concentration of albumin and insulin because of the blood-CSF barrier. This is the major reason for cerebral edema and the resultant blood perfusion deficit when brain or spinal cord is injured. A composition and method for treating brain and spinal cord are provided. The ... 03/09/06 - 20060051294 - Method of predicting a diet effect A method of predicting a diet effect caused by a sympathetic activator includes: making a human ingest the sympathetic activator; obtaining a biological reaction index from the human who has ingested the sympathetic activator; and calculating a predictive value of a diet effect from the biological reaction index based on ... 02/16/06 - 20060034762 - Method for measuring skin absorbability A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the ... 02/16/06 - 20060034761 - Heat shock protein as a targeting agent for endothelium-specific in vivo transduction The present invention relates to the use of Heat Shock Proteins and fragments thereof as targeting ligand. The Heat Shock Protein may be labeled with imaging agents that are capable of binding lectin-like oxidized low-density lipoprotein (LOX-1) or may be attached to a therapeutic agent. The sequences are useful for ... 02/09/06 - 20060029550 - Methods of treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which involves detecting the presence of small intestinal bacterial overgrowth (SIBO) in a human subject having at least one symptom ... 02/09/06 - 20060029549 - Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled water Provided herein are methods for measuring protein biosynthesis by using 2H2O or radioactive 3H2O and applicable uses thereof. ... 02/09/06 - 20060029548 - Methods of diagnosing, monitoring and treating pulmonary diseases The invention includes methods of discriminating asthma from obstructive pulmonary disease, of treating pulmonary diseases, of treating cough, of assessing the efficacy of a treatment for an obstructive pulmonary disease, and of inhibiting activation of a P2-purinoreceptor (P2R). ... 02/09/06 - 20060029547 - Biological materials and methods useful in the diagnosis and treatment of diseases The present invention relates to a method of making a β-form of a prion protein which preferably has more β-sheet than α-helix structure and is soluble in the absence of a denaturant and/or is non-aggregated and exhibits partial resistance to digestion with proteinase K. The invention also relates to use ... 02/09/06 - 20060029546 - Materials and methods for identifying anti-schizophrenic agents The invention relates to materials and methods of identifying modulators of N-methyl-D-Aspartate (NMDA) receptor phosphorylation and function, including anti-schizophrenic agents that modulate NMDA receptor function. The methods of the invention utilize animal models of schizophrenia and cell-based assays to identify modulators of NMDA function. The invention further provides anti-schizophrenic agents ... 02/02/06 - 20060024233 - Use of biomolecular targets in the treatment and visualization of brain tumors The present invention relates to the use of proteins that are differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as biomolecular targets for brain tumor treatment therapies. Specifically, the present invention relates to the use of immunotherapeutic and immunoimaging agents, which specifically bind to one ... 01/26/06 - 20060018832 - Methods of marking and testing pharmaceutical products Methods of marking pharmaceutical products for use in clinical trials and for determining the origin or authenticity of the marked products are provided that use a variety of natural materials as markers. The natural materials have unique genetically controlled micromorphological structures that can be identified using enhanced visualization techniques. For ... 01/19/06 - 20060013769 - Transdermal drug delivery formulations and method of determining optimal amounts of vasodilators therein A method for determining and demonstrating the role of vasodilator chemical agents in the development and practice of transdermal drug delivery systems. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. ... 01/19/06 - 20060013768 - Injection of a radioactive dye for sentinel lymph node identification A one-step procedure for sentinel lymph node identification and biopsy using a single compound, a radiolabeled, low molecular weight dye (e.g., 125I-labeled methylene blue). This radiolabled dye is mixed with an unlabeled, similar molecular weight dye (e.g., isosulfan or methylene blue). The mixture is injected at the time of surgery, ... 01/05/06 - 20060002856 - Methods for in vivo evaluation of physiological conditions and/or organ or system function including methods to evaluate cardiopulmonary disorders such as chronic heart failure using polarized 129xe In certain embodiments, methods of the present invention obtain NMR spectroscopy signal data that corresponds to the behavior of the polarized 129Xe at a selected site(s) in selected environments in vivo. The gas exchange signal data can be used to evaluate: (a) the thickness of a barrier, such as a ... 12/29/05 - 20050287070 - Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria The present invention relates in general to spectroscopic methods for direct observation of membrane dynamics in living cells and their application to drug discovery methods. More particularly, the present invention relates to methods for observing iron transport activity in the outer membrane of living bacteria and more specifically to a ... 12/29/05 - 20050287069 - Method of determining performance of an antiperspirant compositions A method of determining performance of anhydrous antiperspirant compositions comprising an antiperspirant active, a liquid carrier, and a structurant. The compositions, processes, and methods of the present invention provide enhanced antiperspirant performance. ... 12/29/05 - 20050287068 - Efficacy of active immunotherapy by integrating diagnostic with therapeutic methods The invention described herein relates to improved strategies for designing and practicing treatments and clinical trials based upon active immunotherapy protocols, particularly by making diagnostic use of portions of the therapeutic regimen and adjusting the course of treatment if necessary. Embodiments of the invention include methods for determining a course ... 12/22/05 - 20050281742 - Method of determining an individual's level of tolerance to application of a product to skin of the individual, and a kit for implementing such a method A method of determining an individual's level of tolerance to application of a cosmetic product to skin of the individual may include: applying a substance onto a test zone of the skin, the substance containing at least one agent for stimulating the peripheral nervous system; exerting a mechanical action on ... 11/17/05 - 20050255043 - Bacteriophage imaging of inflammation Labeled bacteriophage are disclosed which are useful for detecting a bacterial infection in vivo. ... 11/10/05 - 20050249665 - Urea-, glycerate- and, hydroxyamide-headed hydrocarbon chain lyotropic phases forming surfactants The invention provides a compound containing a head group based on urea, glycerol or glycerate and a tail selected from the group consisting of a branched alkyl chain, a branched alkyloxy chain or an alkenyl chain. The compounds may be used as surfactants to form a lyotropic phase that is ... 10/27/05 - 20050238580 - Use of 4-galactosyl-xylose in humans for the in vivo evaluation of intestinal lactase as a non-invasive diagnostic test of the deficiency of said enzyme The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl-xylose to the ... 10/20/05 - 20050232862 - Combination therapy for the treatment of estrogen-sensitive drugs The present invention provides methods which increase the effectiveness of combination drug therapies for treating estrogen-sensitive diseases, such as breast cancer, as well as novel combinations useful to treat such diseases. ... 10/13/05 - 20050226814 - Diagnostic method and kit for implantation of a sustained release drug-delivery implant with a steroid The present invention is a method of the present invention screens a patient with macular edema associated with visual loss for implantation of a sustained release drug-delivery implant that is less invasive than implanting a drug-delivery implant and is minimally invasive. The method comprises injecting a first steroid, eg. triamcinolone ... 10/06/05 - 20050220709 - Diagnostic methods for therapeutic compounds and methods for monitoring azathioprine therapy The present invention provides diagnostic methods for predicting therapeutic efficacy in an individual being treated for an autoimmune or an inflammatory disease. In addition, the present invention also provides novel methods for monitoring azathioprine therapy or optimizing clinical responsiveness to azathioprine therapy in an individual by measuring 6-thioguanosine nucleotide levels ... 10/06/05 - 20050220708 - Skin test for detecting non-allergic hypersensitivity Non-allergic hypersensitivity reactions can be observed in a subject in response to anaphylatoxins. Accordingly methods are provided for detecting non-allergic hypersensitivity in a subject referred to as “pseudo-allergic reactions”. Also provided are kits for detecting non-allergic hypersensitivity and hyper-responsiveness in a subject. ... 10/06/05 - 20050220707 - Mammalian agmatinase inhibitory substance The present invention provides for methods and compounds for treating brain trauma and disorders such as: ischemia, stroke, neurodegenerative disorders, opioid addiction, idiopathic pain, epilepsy, and depression. More specifically, the invention provides methods for designing and identifying inhibitors of mammalian agmatinase and for compounds identified by these methods. ... 09/29/05 - 20050214218 - Therapeutic methods and compositions using viruses of the recombinant paramyxoviridae family The invention relates to compositions and methods for treating a patient having a tumor in order to reduce tumor size, comprising administering to the patient a replication-competent Paramyxoviridae virus comprising two or more of a) a nucleic acid sequence encoding a heterologous polypeptide, wherein upon administration the heterologous polypeptide is ... 09/29/05 - 20050214217 - Methods of and pharmaceutical compositions for modulating t-lymphocyte adhesion, migration, gene expression and function by glutamate and analogs thereof Methods and compositions for the direct modulation of T-cell activity by the action of glutamate and glutamate functional analogs, effecting gene expression and cytokine secretion, integrin-mediated adhesion, and chemotactic migration for the treatment of infectious diseases, inhibition and prevention of tumor growth and dissemination, prevention and treatment of neurological disease, ... 09/29/05 - 20050214216 - Diagnostic microspheres The invention provides a diagnostic composition for detecting both aspiration and gastroesophageal reflux comprising bio-degradable microspheres having a diameter of about 0.1-10 microns. ... 09/29/05 - 20050214215 - Method of diagnosing changes in the intestinal absorptive surface in an individual The invention relates to a method of diagnosing changes in the intestinal absorptive surface in an individual. According to the invention, an immunoassay is performed on samples of serum and/or plasma from the blood of the patient in order to determine the quantity of human apolipoprotein apoA-IV using a specific ... 09/29/05 - 20050214214 - Staining agent in tablet form for making visible the formation of dental plaque and method for producing such a tinting agent A staining agent in tablet form for making visible dental plaque contains 85 to 95% by weight lactose; 1.5 to 2.6% by weight phloxin B; 2.5 to 3.5% by weight FDA Blue No. 1; 0.15 to 0.25% by weight magnesium stearate. The staining agent is produced by direct compression tableting ... 09/22/05 - 20050207978 - Dental-caries detecting solution Disclosed is a dental-caries detecting solution prepared by dissolving a dye capable of staining a carious region of a tooth to provide enhanced visibility of the carious region, in a water-miscible organic solvent, which is capable of distinctively staining only a first decalcified layer, or an outer layer of a ... 09/15/05 - 20050201935 - Method of promoting skin care products The present invention relates to a method of assessing the efficacy of skin care products by comparing images of the skin prior to and after use of said skin care product. ... 08/25/05 - 20050186137 - Novelty-induced hypophagia-based assays for identifying agents to treat anxiety and depression This invention provides a method for determining whether an agent reduces anxiety and/or depression in a depressed, non-human subject. This invention also provides methods for treating anxiety and depression in subjects afflicted with those disorders comprising administering a therapeutically effective amount of an anxiety-reducing or depression-reducing agent identified by the ... 08/11/05 - 20050175537 - Process, system, and kit for evaluating the relief of the skin with a substrate A process, system, and kit for evaluating the relief of the skin using a substrate with an adhesive surface. The process includes the steps of applying the substrate onto a test zone of the skin so that the adhesive surface is in contact with the skin at contact locations; removing ... 07/28/05 - 20050163711 - Intra-dermal delivery of biologically active agents The present invention relates to methods and devices for delivering one or more biologically active agents, particularly a diagnostic agent to the intradermal compartment of a subject's skin. The present invention provides an improved method of delivery of biologically active agents in that it provides among other benefits, rapid uptake ... 07/14/05 - 20050152839 - Methods for isolation of proanthocyanidins from flavonoid-producing cell culture A method for isolation of proanthocyanidins from flavonoid-producing cell cultures is disclosed. More specifically, the invention relates to the isolation of catechin, epicatechin, proanthocyanidin B-2, and other proanthocyanidins from Vaccinium pahalae Skottsberg cultures. The invention also provides a method for modifying the content of proanthocyanidins in a flavonoid-producing culture. Further, ... 07/07/05 - 20050147560 - 13c glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control Use of 13C glucose in an analytical assay to monitor glucose metabolism by measurement of labeled exhaled CO2 is provided. A breath test and kit for performing the breath test are described for the diagnosis of diabetic indications and monitoring of glycemic control. The breath test utilizes the measurement of ... 07/07/05 - 20050147559 - Internal drug dispenser capsule medical device The present invention provides a swallowable internal drug medical device. The device includes a swallowable capsule. A sensing module is disposed in the capsule. A bioactive substance dispenser is disposed in the capsule. A memory and logic component is disposed in the capsule and in communication with the sensing module ... 07/07/05 - 20050147558 - Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled water Provided herein are methods for measuring protein biosynthesis by using 2H2O or radioactive 3H2O and applicable uses thereof. ... 07/07/05 - 20050147557 - Diagnostic agents for pancreatic exocrine function Y1 is a 13C-labeled alanine molecule optionally having a protecting group. ... 06/30/05 - 20050142063 - Microparticle-based diagnostic methods The present invention concerns novel materials and methods to detect low frequency surface changes utilizing modified microspheres. Upon exposing the surface to the modified microspheres of the subject invention, the microspheres selectively adhere to any targeted surface marker. ... 06/16/05 - 20050129617 - Type1 diabetes diagnostics and therapeutics The invention provides compounds and methods useful for the diagnosis, prediction, therapy, or prophylaxis of type 1 diabetes. The compounds of the invention include peptides derived from IAPP (islet amyloid polypeptide) precursor peptides. ... ### FreshPatents.com Support |