FREE patent keyword monitoring and additional FREE benefits. /images/triangleright (1K) REGISTER now for FREE triangleleft (1K)
Fresh Patents
Monitor Patents Patent Organizer File a Provisional Patent Browse Inventors Browse Industry Browse Agents Browse Locations


Liquid Purification Or Separation > Processes > Chromatography

Chromatography

Chromatography patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

01/10/08 - 20080006581 - method for separation and enrichment of phosphopeptides
The present invention relates to phosphopeptide isolation and enrichment, particularly to a highly selective and specific phosphopeptide enrichment method. The method mentioned in the invention is based on the strong interaction between zirconium phosphonate and phosphopeptide. Zirconium phosphonate is immobilized on the surface of matrix for phosphopeptide enrichment. Zirconium phosphonate ...

12/27/07 - 20070295664 - Focusing a sample on an analytical column
A focusing unit for a fluidic system adapted for processing a mobile phase containing a fluidic sample, the fluidic system having a first processing element and a second processing element each for interacting with the mobile phase, wherein the mobile phase is to be conducted through the first and second ...

12/27/07 - 20070295663 - Frit for high pressure liquid chromatography
A frit (44) includes a porous support structure having a plurality of void spaces, where a plurality of secondary particles (46) are filled in the void spaces, the secondary particles (46) being dimensioned with respect to the void spaces such that the frit (44) retains packing materials with diameters of ...

12/13/07 - 20070284309 - Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same
A composite semipermeable membrane, which comprises a separating functional layer comprising polyamide formed on a porous substrate film, wherein the separating functional layer comprising polyamide has a mean pore radius of 0.25 nm to 0.35 nm and a vacancy content of 0.2 nm3% to 0.3 nm3%, measured by positron annihilation ...

11/22/07 - 20070267349 - Method of separating components in a sample using silane-treated silica filter media
The present invention provides methods for separating one or more components of interest from a sample containing particulates and soluble materials. The method comprises the steps of: (a) filtering a sample through silica filter media whose surface silanol groups have reacted with one or more silanes, and (b) simultaneously capturing ...

11/22/07 - 20070267348 - Open tubular capillaries having a connecting layer
The invention relates to a method for producing open tubular capillaries containing monolithic sorbents and to said capillaries. The inventive capillaries are characterised by a connection layer between the capillary wall and the sorbent, said layer ensuring a particularly good adhesion of the sorbent to the capillary wall. ...

11/15/07 - 20070262021 - System for automated compression of chromatography columns
The present invention provides an automated system and method for maintaining compaction, and therefore increased efficiency, of a media bed within a chromatography column. In the preferred embodiment, an adjustment assembly is slidingly engaged inside one end of the column such that it can be moved along the column's major ...

10/25/07 - 20070246427 - System and method for processing identified metabolites
A method of rapidly analyzing unexpected metabolites in a metabolite analyzing system is disclosed. A control sample is run and analyzed to generate an exclusion list of unwanted sample components. A single analyte sample is then run and programmatically uses the exclusion list containing the unwanted metabolites to dynamically filter ...

10/11/07 - 20070235390 - Titanium-coated sorbents as a separation medium for hplc of phosphorus-containing materials
Methods for the separation of phosphorus-containing biological materials from a sample mixture are provided. The methods use a solid support comprising a Ti(IV) metal-coated sorbent matrix. Methods using the support as a chromatographic column for separation are also provided. The present disclosure also provides methods for making a Ti(IV) metal-coated ...

09/20/07 - 20070215549 - Separating agent for enantiomeric isomers
The present invention provides a separating agent for enantiomeric isomers having no large UV absorption, as represented by an aromatic group, and having high asymmetric recognizability, particularly, high asymmetric recognizability in an aqueous mobile phase, or a separating agent for enantiomeric isomers containing a polysaccharide alicyclic ester derivative free from ...

09/20/07 - 20070215548 - Systems and methods for packing chromatography columns
Various embodiments of the present invention are directed to systems and methods for packing chromatography columns. In one described embodiment of the present invention, a compressible resin is combined with a relatively high-viscosity packing solution to form a resin slurry for packing within a chromatography-column tube. In an alternative embodiment ...

09/20/07 - 20070215547 - Porous hybrid monolith materials with organic groups removed from the surface
A material for chromatographic separations, processes for its preparation, and separation devices containing the chromatographic material. In particular, porous inorganic/organic hybrid monoliths are provided with a decreased concentration of surface organic groups, and have improved pH stability, improved chromatographic separation performance, and improved packed bed stability. These monoliths may be ...

09/06/07 - 20070205156 - Novel ion exchange porous resins for solid phase extraction and chromatography
Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance. ...

08/23/07 - 20070193954 - Method of preparing a separation matrix
The present invention is a method of preparing a separation matrix, which method comprises providing unsaturated monomers comprising one or more chromatography functionalities; contacting said monomer(s) with initiator and catalyst; performing controlled radical polymerisation of said monomers; and coupling of the resulting polymers to a base matrix. The controlled polymerisation ...

08/09/07 - 20070181505 - Chromatography system and method
A chromatography system and method for analyzing a sample of interest. The chromatography system can include a housing, a cartridge holder coupled to the housing and formed to hold a chromatography cartridge containing a stationary phase, a collection vessel stand holder coupled to the housing and formed to hold a ...

08/09/07 - 20070181504 - Method of preparing a composition using argentation chromatography
The present invention is directed to a method of preparing compositions enriched in compounds containing carbon chains of varying degrees of unsaturation using argentation chromatography. The present method utilizes an argentized cationic resin or a conditioned argentized alumina to separate compounds containing saturated or mono-unsaturated carbon chains from compounds having ...

08/09/07 - 20070181503 - Affinity particle and affinity separation method
The object of the present invention is to provide an affinity separation method that uses affinity particles utilizing inexpensive inorganic particles and is capable of separating the target substance easily and with high accuracy. ...

08/09/07 - 20070181502 - Adsorbent with multiple layers
A method, article of manufacture and apparatus are disclosed for binding successive layers of a “guest specie” such as an atom, cation, anion, organic molecule, and/or pathogen to a substrate or multiple different substrates. Possible substrates include materials with a porous nature; macro, micro and nano porous materials are all ...

08/09/07 - 20070181501 - Method and apparatus for packing chromatography column
An apparatus for packing a chromatography column with a granular packing medium is disclosed. The apparatus includes a chamber adapted to hold a mixture of the packing medium and a liquid. The chamber is in fluid communication with a pump and the column. A vibrator is positioned so as to ...

07/19/07 - 20070163962 - Fraction collection in high performance liquid chromatography
A system and method for substantially continuous fraction collection includes a control device and a fluidic switch. The control device selects the state of the fluidic switch, and thereby determines which of a plurality of output ports effluent will exit. ...

07/19/07 - 20070163961 - Separating agent for enantiomeric isomer
The present invention provides a separating agent for enantiomeric isomers which exhibits stable separating performance, high optical resolving power, and sufficient solvent resistance at the same time. The separating agent for enantiomeric isomers includes an optically active polymer compound such as cellulose or amylose carried on a carrier such as ...

07/19/07 - 20070163960 - Chromatographic separation method, separation device and process for the preparation of a separation medium for use therein
A method for the chromatographic separation of substances contained in a liquid sample is disclosed which method comprises providing a one piece separation tray having a spaced array of discrete identical upstanding chambers each exhibiting an open upper end and an open lower end and a separation medium placed in ...

07/12/07 - 20070158269 - Method for separating betaine
The invention relates to a method for separating betaine from fermentation process solutions, vinasse and other sugar beet based solutions on a weakly acid cation exchange resin in H+-form in the chromatographic separation process. The present invention relates also to use of a weakly acid cation exchange resin in H+-form ...

07/05/07 - 20070151928 - Purification of immunoglobulins
The present invention relates to a separation matrix comprised of a porous support to which ligands have been immobilised, wherein said ligands comprise at least one aliphatic sulphonamide. The nitrogen of the sulphonamide may be a secondary or tertiary amine. The invention also relates to a chromatography column that contains ...

06/28/07 - 20070144972 - Monolithic organic copolymer for biopolymer chromatography
Monolithic organic copolymer prepared by copolymerisation of an alkylstyrene and a divinylbenzene or a derivative thereof in the presence of a porogen, wherein said porogen comprises decanol and at least one of the group consisting of tetrahydrofuran and toluene. ...

06/28/07 - 20070144971 - Monolithic organic copolymer for biopolymer chromatography
Monolithic organic copolymer prepared by copolymerisation of an alkylstyrene and a divinylbenzene or a derivative thereof in the presence of a porogen, wherein said porogen comprises decanol and at least one of the group consisting of tetrahydrofuran and toluene. ...

06/21/07 - 20070138100 - Detection systems and methods
The application describes apparatus and methods using ultrasound transmitted through a chromatography column bed to determine the status of materials in the bed space, particularly during chromatography runs. Detected conditions include the profile of a band of eluting material—to see whether it is satisfactory—the arrival of a band of material ...

06/21/07 - 20070138099 - Device for recovering material to be measured and method for recovering material to be mesured
Device for recovering a material to be measured comprising a reservoir filled with a sample holding material impregnated with a sample liquid in which a material to be measured is dissolved and an adsorbing column for adsorbing the material to be measured, wherein the reservoir and the adsorbing column are ...

06/21/07 - 20070138098 - Chromatography columns and their operation
A method of operating chromatography column apparatus comprising a column tube (101) and first and second discrete end cell structures, associated with the respective ends of the column tube and positionable to close off the column tube and define therein a column space for retaining chromatography medium in use of ...

06/21/07 - 20070138097 - Preanalysis treatment method and apparatus for analysis of polycyclic aromatic hydrocarbons
The present invention provides a preanalysis treatment method for nitropolycyclic aromatic hydrocarbons present in diesel engine exhaust particulates and the like. The method comprises feeding a test solution 160 in which a sample containing polycyclic aromatic hydrocarbons is dissolved in a solvent to a silica gel column 170 using an ...

06/14/07 - 20070131616 - Optically active maleimide derivatives, optically active polymaleimide derivatives, process for their production, separating media comprising the optically active polymaleimide derivatives and method of separating optically active compounds using them
(where the various substituents are as defined in the description) are used as separating media for separating optical isomers and geometrical isomers such as by high performance liquid chromatography. ...

06/14/07 - 20070131615 - Disposable chromatography valves and system
Described is a disposable valve that includes an actuation layer operationally linked to a flexible diaphragm; a valving layer operationally linked to the flexible diaphragm; and a connection layer operationally connected to the valving layer; wherein the valving layer and the connection layer have a corresponding plurality of channels passing ...

06/07/07 - 20070125712 - Anion-exchange displacement chromatography process and anionic organic compounds for use as displacer compounds in anion-exchange displacement chromatography process
displacing at least one of the one or more component from the stationary phase by applying to the stationary phase a mixture comprising an polyaromatic polyanionic displacer compound having a general formula Cen (Ar)w, in which Cen is a central bond or group, Ar is an aromatic nucleus, w=2 to ...

06/07/07 - 20070125711 - Novel separation matrix
The present invention relates to a separation matrix comprised of ligands coupled to the surfaces of a porous support, such as one or more porous particles, wherein the ligands provide at least one chemical gradient within the support. In the most advantageous embodiment, the chemical gradient is a ligand density ...

05/10/07 - 20070102363 - Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process
each An− independently may be one or more organic or inorganic, monovalent or polyvalent anion as needed to obtain a neutral compound. ...

05/10/07 - 20070102362 - Chip
In a chip (215), an inlet (217), a main channel (221), a separation region (218), and dispensing channels (222) are formed on a substrate (216). It is structured such that a plurality of the dispensing channels (222) are communicated with the main channel (221), and detection reservoirs (223) are communicated ...

05/03/07 - 20070095757 - Methods and systems for the annotation of biomolecule patterns in chromatography/mass-spectrometry analysis
The method and measurement system according to the invention performs combined Chromatography and Mass Spectrometry analysis and comprises the steps of: performing an C/MS analysis 300; generating at least one first elution profile 305, wherein one dimension is an elution time of the chromatography, and one dimension is mass to ...

04/26/07 - 20070090053 - Automated packing system and method for chromatography columns
A column packing system comprises a control unit provided with software for monitoring the column interior pressure and/or flow through the column for use in calculating the breakpoint where a movable adapter comes into contact with a consolidated bed of bed media. The calculated breakpoint is used by the control ...

04/26/07 - 20070090052 - Chromatographic stationary phase
Provided is a composition of matter comprising a chromatographic stationary phase. The chromatographic stationary phase has bonded thereto, two different active silyl moieties. By combining two different active moieties on the same solid support, the activity of the chromatographic stationary phase can be tailored to a particular application. The active ...

03/29/07 - 20070068872 - Nano-flow liquid chromatographic apparatus having robust capillary tubing
A chemical processing apparatus includes a separation column, a pump unit configured to support nano-flow processing, at least one fluid transport tube for transporting the fluid between the pump unit and the separation column, and a connector disposed adjacent to an inlet or outlet end of the at least one ...

03/22/07 - 20070062874 - High efficiency sol-gel gas chromatography column
A capillary column (10) includes a tube structure having inner walls (14) and a sol-gel substrate (16) coated on a portion of inner walls (14) to form a stationary phase coating (18) on inner walls (14). The sol solution used to prepare the sol-gel substrate (16) has at least one ...

03/22/07 - 20070062873 - Recycled suppressor regenerants
A suppressed ion chromatographic apparatus using a regenerant recycle loop, comprising (a) an ion separation device, (b) a membrane suppressor, (c) a detector, (d) a container for regenerant solution, (e) a first conduit between the ion separation device and the suppressor, (f) a second conduit between the regenerant solution container ...

03/15/07 - 20070056908 - Nucleic acids in the form of specific novel chiral selectors
The invention relates to chiral separation chromatographic and electrophoretic techniques. The aim of said invention is to obtain chiral stationary and mobile phases comprising an oligonucleotide which is specifically selected by a SELEX method against an enantiomer to be separated as a special-purpose chiral selector. Methods for separating enantiomers by ...

03/01/07 - 20070045190 - System and method for feature allignment
In a system and method for feature alignment in chromatographic systems, the system runs a first sample through a first separation column. The system determines a first set of features for the first sample run. The system runs a second sample through a second separation column and detects a second ...

02/22/07 - 20070039891 - Separation of proteins based on isoelectric point using solid-phase buffers
Proteins can be separated from mixtures, based on their pI values, through the use of a series of chromatographic materials, each comprising a solid buffer and an ion exchange resin. Each solid buffer generates a stable pH, such that passing proteins possess a net charge and can be separated by ...

02/22/07 - 20070039890 - Separating agent for enantiomeric isomers
(in the formulae, R represents a substituted or unsubstituted aromatic group, or a linear, branched, or cyclic aliphatic group). ...

02/15/07 - 20070034572 - Low pressure anion chromatographic apparatus and method having two or more eluents
A low pressure anion chromatography apparatus that includes a first eluent reservoir that contains a first eluent, a second eluent reservoir that contains a second eluent, and a valve for switching flow between the first and the second eluent reservoirs. The low pressure anion chromatography apparatus also has a low ...

01/25/07 - 20070017870 - Multicapillary device for sample preparation
A multicapillary sample preparation device, especially useful for handling biological samples, comprising a plurality of uniform capillary tubes coated with a stationary phase, and arranged in a monolithic element. The multicapillary device is suitable for attachment to a pipette, micropipette, syringe, or other analytical or sample preparation instrument. ...

01/25/07 - 20070017869 - Liquid chromatography chip with flexible interface
A liquid chromatography chip may include an analytical column. After an analyte has traveled through an analytical column defined by the chromatography chip, the analyte is routed, either directly or indirectly, to a port defined by the chromatogrpahy chip, instead of to a spray tip on-board the chromatography chip. The ...

01/18/07 - 20070012627 - Narrow i.d. monolithic capillary columns for high efficiency separation and high sensitivity analysis of biomolecules
A method of preparing an ultra-nanoscale-LC monolithic separation medium for use in capillary columns, or channels in microfabricated devices (microchips), and capillaries prepared by the method are disclosed. The application of moderate positive pressure to both ends of the capillary during the monolith polymerization process permits the preparation of monolithic ...

01/18/07 - 20070012626 - Automated packing system and method for chromatography columns
A column packing system comprises a control unit provided with software for calculating the breakpoint where a movable adapter comes into contact with a settled bed of bed media. The calculated breakpoint is used by the control unit to determine how much further the movable adapter has to move into ...

01/04/07 - 20070000838 - Integrated chromatography devices and systems for monitoring analytes in real time and methods for manufacturing the same
Systems and methods for monitoring analytes in real time using integrated chromatography systems and devices. Integrated microfluidic liquid chromatography devices and systems include multiple separation columns integrated into a single substrate. Using such a device, parallel analysis of multiple samples can be performed simultaneously and/or sequential analysis of a single ...

12/07/06 - 20060273013 - Versatile simulated moving bed systems
Distributed valve simulated moving beds are described in which junctions located between successive columns interrupt the flow of process fluid between columns, and either transmit the process fluid through a zone bypass to a succeeding column within the same zone or, if the junction is located between zones, direct the ...

12/07/06 - 20060273012 - Column with additional fluid introduction
A chromatography column which comprises an adsorbent bed, located in a first fluid flow path between a fluid inlet and a fluid outlet, is provided, and which comprises at least one distribution device, extending into the adsorbent bed and being adapted for fluid introduction. Furthermore methods are provided permitting preconditioning ...

12/07/06 - 20060273011 - Systems for selecting analytical device methods
Systems and processes for using the same for selecting analytical device methods are provided. Also provided are computer program products for executing the subject processes. ...

12/07/06 - 20060273010 - Systems for developing analytical device methods
Systems and processes for using the same for developing analytical device methods are provided. Also provided are computer program products for executing the subject processes. ...

11/30/06 - 20060266709 - Method of separating optical isomers through supercritical fluid chromatography
A supercritical fluid chromatography using a column using a column having an optical isomer separating agent containing a polysaccharide derivative capable of optical isomer separation, wherein use is made of a mobile phase containing a supercritical fluid and wherein as the optical isomer separating agent received in the column to ...

11/30/06 - 20060266708 - Integrated on-line two-dimensional method and device for synchroned analytical temperature rising elution fractionation and gel permeation chromatography
An analytical method comprising performing a first fractionation of a polymer sample based on differences in crystallizability to provide a first set of sample fractions, performing a first analysis on the first set of sample fractions, performing a second fractionation of the first set of sample fractions to produce a ...

11/30/06 - 20060266707 - Drying method for macroporous polymers, and method of preparation and use of macroporous polymers made using the method
The invention provides for dyring methods for macroporous polymers that provide improved performance characteristics. The polymers are easy to pack and especially useful in large scale chromatography columns. ...

11/09/06 - 20060249459 - Method and device for injecting sample
In a chromatography using a pressurized mobile phase, the mobile phase flowing through a feed pipe (31) is introduced into one end of a bypass pipe (32) where a sample is sealed through a two-way valve (v2), a two-way valve (v3) is opened and a two-way valve (v1) is closed ...

11/09/06 - 20060249458 - Method of substance separation by supercritical fluid chromatography and vapor liquid separator for use therein
A method comprising liquefying a gas to thereby obtain a liquefied gas; injecting a sample into a mobile phase containing a solvent and a supercritical fluid formed from the liquefied gas; passing this mobile phase through a column so that the mobile phase containing desired substance is divided into the ...

11/09/06 - 20060249457 - Matrix for separation of polyethers and method of separation
The present invention relates to a separation matrix comprised of a support to the surfaces of which polymer chains have been coupled, wherein each polymer chain presents recurring proton-donating groups and at least the surface of the support is substantially hydrophilic. In the most advantageous embodiment, the support is porous ...

10/26/06 - 20060237368 - Twisted pi-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices
Unconventional twisted π-electron system electro-optic (EO) chromophores/compounds, compositions and related device structures. Crystallographic analysis of several non-limiting chromophores reveals, for instance, large ring-ring dihedral twist angles and a highly charge-separated zwitterionic structure in the ground state, in both solution phase and solid-state. ...

10/26/06 - 20060237367 - Polymeric adsorbent, and method of preparation and use
Macroporous polymers having selected porosity and permeability characteristics that provide rigid polymer matrices suitable for use in medium and high pressure reversed phase liquid chromatography (RPC) are disclosed. A method for preparing the polymers is also disclosed. The polymers are especially useful as stationary phases in large scale chromatography columns ...

10/19/06 - 20060231494 - Carbon nanotube stationary phases for chromatography
A packing material for a chromatography column is described. The packing material comprises a support structure. The packing material also comprises a stationary phase adjacent to the support structure and comprising a carbon nanotube material. ...

10/12/06 - 20060226082 - Methods for substrate and modulator screening using enzyme-reactor chromatography/tandem mass spectrometry
The present invention relates to a method of screening compounds for modulation and binding to proteins, in particular proteins that have been immobilized in a monolithic chromatographic stationary phase. The method involves observing the conversion of a substrate to product by the protein and determining a product to substrate ratio. ...

10/05/06 - 20060219639 - Novel separation agent for separating optical isomer and method for preparation thereof
A method of producing a novel separating agent for separating enantiomeric isomers, characterized by including: a step of supporting an optically active polymer compound and a compound having an asymmetric structure of a molecular weight of 1,000 or less on a carrier using a solvent; a step of removing the ...

10/05/06 - 20060219638 - Method and device for multidimensional liquid chromatography
In a liquid chromatography, an electrolytic solution starts to be supplied from an injector toward a specimen in a first separating column to transfer components of the specimen from the first separating column toward one of first and second trap columns after a time period more than zero elapses from ...

10/05/06 - 20060219637 - Devices, systems and methods for liquid chromatography
Devices comprising a mechanism for selectively diverting a portion of a mobile phase flowing through a mobile-phase transporting conduit to a fluid-transporting conduit comprising a stationary phase for separating sample components are disclosed, as well as systems and methods for using the same. ...

10/05/06 - 20060219636 - Siloxane-immobilized particulate stationary phases for chromatographic separations and extractions
Chromatography and solid phase extraction devices having immobilized stationary phases are disclosed. An exemplary device of the Invention includes a column or cartridge packed with a mixture of a particulate stationary phase material and a polymeric network of Cross-linked poly(diorganosiloxane), e.g., poly(dimethylsiloxane). The Invention also provides methods of making and ...

09/28/06 - 20060213838 - Elution test method and apparatus
An elution test method measures the elution process of a specific component in a process where a preparation containing at least the specific component subject to a change with time in chemical properties after elution and an impurity component not subject to a change with time in chemical properties after ...

09/28/06 - 20060213837 - Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method
In liquid-feeding sections for feeding two types of mobile phases A, B, respectively, actual flow rate measuring sections capable of detecting back-flows are provided in downstream of liquid-feeding pumps, respectively. Control devices control driving of the liquid feeding pumps, respectively, so that measured flow rates by the actual flow rate ...

09/21/06 - 20060207941 - Liquid chromatograph analysis apparatus and method
A liquid chromatograph analysis apparatus includes: a macro storing section for storing a macro program having various commands related to a purge operation; a macro executing section for reading the macro program and analyzing and executing the program thus read; and a solvent database in which information on properties of ...

09/21/06 - 20060207940 - Adsorbent, adsorption apparatus, and method for manufacturing the adsorption apparatus
An adsorption apparatus has a column having an adsorbent filling space filled with an adsorbent. The adsorbent has a surface and its vicinity mainly comprises an apatite which is represented by the formula (Ca1-aMa)10(PO4)6((OH)1-bXb)2, where the M represents at least one kind of rare earth metal elements, the X represents ...

09/21/06 - 20060207939 - Separation system, components of a separation system and methods of making and using them
Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. ...

09/21/06 - 20060207938 - Silica gel bonded with cucurbituril
A cucurbituril-bonded silica gel and its use are provided. The cucurbituril-bonded silica gel is useful for removal of air pollutants or water contaminants, and separation and purification of biological, organic, inorganic, or ionic substances. ...

09/14/06 - 20060201886 - Method for determining the binding behavior of ligands which specifically bind to target molecules
The invention relates to a method for determining the binding behavior of ligands which specifically bind to target molecules at at least one binding site, whereby the markers are present in a native form and the determination of the concentrations K4 and K5 or of the quantities M2 and M1 ...

09/14/06 - 20060201885 - Chromatographic solvent monitor
A bubbler is positioned within a solvent reservoir of a chromatographic system with its opening near the bottom of the system to measure the pressure of solvent. The bubbler may use air or may use helium or some other gas so that the solvent can be purged of excess air ...

09/07/06 - 20060196832 - System for automated compression of chromatography columns
The present invention provides an automated system and method for maintaining compaction, and therefore increased efficiency, of a media bed within a chromatography column. In the preferred embodiment, an adjustment assembly is slidingly engaged inside one end of the column such that it can be moved along the column's major ...

08/24/06 - 20060186049 - Methods and system for protein separation
The present disclosure relates to a system and method for membrane protein separation including: fractionating a membrane sample on a reversed-phase superficially porous stationary phase at a temperature of greater than or equal to about 40° C. to recover a protein greater than about 70 weight percent of the mixture ...

08/24/06 - 20060186048 - Method for fluid sampling
The present disclosure relates to a method for sampling a fluid, such as air. As fluid flows through a device, a scrubbing liquid is positioned in a pattern to contact the fluid and constituents in the fluid are transferred to in the liquid. ...

08/24/06 - 20060186047 - Material for chromatography
Granulated products are provided and include carbonaceous particles and a carbonized agent or binder. The agent or binder is preferably a synthetic resin, pitch component, or mixture thereof. Packing materials for packing columns used in chromatographic separations are also provided as are methods of chromatographic separation using the materials. In ...

08/24/06 - 20060186046 - Ion chromatography system using catalytic gas elimination
A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ion chromatographic system in which the effluent from the detector ...

08/17/06 - 20060180549 - Organosilanes and substrates covalently bonded with same and methods for synthesis and use same
The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications. ...

08/10/06 - 20060175260 - Chromatographic separation member and method
There is described a chromatographic separation member including a substrate carrying on at least one surface a thin layer of a chromatographically active capture material. Also described is a chromatographic separation method for separating a component of interest from a fluid utilizing the chromatographic separation member. ...

08/10/06 - 20060175259 - Method and apparatus for performing planar electrochromatography at elevated pressure
According to one aspect of the disclosure, there is provided an apparatus (210) for performing electrochromatography. The apparatus (210) includes a die block (222) which is movable to exert a pressure greater than atmospheric pressure on a chromatography sample plate during performance of an electrochromatography procedure. A method of performing ...

08/10/06 - 20060175258 - Method of preparing ligands for hydrophobic interaction chromatography
The invention is a method of preparing multimodal ligands for hydrophobic interaction chromatography (HIC), which comprises providing a cyclic scaffold comprising a thiol, an amine and a carbonyl group; derivatisation of the nitrogen with a reagent to introduce a primary interaction; and aminolysis of the resulting derivative, whereby a secondary ...

08/03/06 - 20060169640 - High throughput screening, purification and recovery system for large and small molecules
The present invention relates to a method and apparatus for chromatographically analyzing/purifying samples in a detector, comprising an autosampler to contain a sample for chromatographic analysis and a chromatographic system comprising a loading pump, and an eluting pump and at least one chromatography column. A detector is included for detecting ...

07/27/06 - 20060163162 - Device for solid phase extraction and method for purifying samples prior to analysis
A solid phase extraction (SPE) device having a reservoir with an opening; a well comprising an internally tapered wall, the well having a wider interior diameter at an end closest to the opening than at an exit spout; a first filter within the well; a bed of sorbent particles within ...

07/27/06 - 20060163161 - Chromatography columns
A chromatography column is prepared with a stationary phase comprising a deuterated poly(ethyleneglycol), or other deuterated polymer. Formation of the stationary phase can be performed using exactly the same methodology as used when forming a stationary phase with the equivalent non-deuterated polymer. The deuterated poly(ethyleneglycol), or other deuterated polymer, preferably ...

06/22/06 - 20060131238 - Ultraporous sol gel monoliths
Ultraporous sol gel monoliths and methods for preparing the same are provided, having superior flow characteristics for chromatography and analytical chemistry applications. The methods for forming an ultra porous sol-gel monolith include (a) forming a solution comprising a porogen, a matrix dissolving catalyst and a sol gel precursor; (b) allowing ...

06/15/06 - 20060124551 - Method and device for sample preparation
The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column, ...

06/15/06 - 20060124550 - Distributing or collecting device
The present invention relates to a fluid distributing device for distributing fluid into a column and to a fluid collecting device for collecting fluid from a column. The invention relates also to methods of using the devices of the present invention. The distributing device and/or the collecting device of the ...

06/15/06 - 20060124549 - Method and device for chromatography comprising a concentration step
The invention concerns a method for multiple-column chromatographic spearation producing at least two fractions, comprsing the following steps: in output of the extract, zone 1, or the raffinate zone, zone III: (i) drawing at least part of the output flow of said zone; (ii) concentrationg said part; and (iii) re-injecting ...

06/08/06 - 20060118492 - Integrated column, related system and method for liquid chromatography
An integrated column for liquid chromatography is disclosed. A system comprising an integrated column and methods of using an integrated column are also described. ...

06/08/06 - 20060118491 - Method and device for desalting an analyte
The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column ...

06/08/06 - 20060118490 - Mesoporous inorganic oxide spheres and method of making same
A method of preparing mesoporous inorganic oxide spherical particles includes providing a reaction mixture capable of producing mesoporous inorganic oxide spheres; heating the reaction mixture to produce mesostructured inorganic oxide particles and removing organic material from the mesostructured inorganic oxide particles to form the mesoporous inorganic oxide spherical particles. In ...

06/08/06 - 20060118489 - System and method for processing identified metabolites
A method of rapidly analyzing unexpected metabolites in a metabolite analyzing system is disclosed. A control sample is run and analyzed to generate an exclusion list of unwanted sample components. A single analyte sample is then run and programmatically uses the exclusion list containing the unwanted metabolites to dynamically filter ...

06/08/06 - 20060118488 - Apparatus and method of utilizing a sawed tooth shaped gradient for chromatographic separation
The present invention provides an apparatus and a method wherein the movement of analytes on a chromatographic separation column is controlled by the manipulation of isocratic and gradient flow. Such manipulation allows for a distinct set of analytes to be eluted from the chromatography column and delivered downstream for further ...

06/01/06 - 20060113252 - Irregularly-shaped macroporous copolymer particles and methods of using same
A matrix comprising irregularly-shaped macroporous copolymer particles is disclosed. The matrix can be employed liquid chromatography applications, such as detecting the presence or absence of a heteroduplex structure in a mixture of hetero- and homoduplex structures. The non-monolithic crushed macroporous copolymer network can be packed in a chromatography column, and ...

05/18/06 - 20060102561 - Regeneration of chromatographic stationary phases
Process for regenerating a chromatographic stationary phase ...

05/11/06 - 20060096924 - Method for discovering suitable chromatography conditions for the separation of biological molecules
The invention relates to a multiparallel chromatography system for developing a method for the purification of proteins and other biomolecules. The system uses cavities of multiwell plates (for example 96 well plates) filled with chromatography gels, and consists of diverse start buffers in which the samples to be chromatographed are ...

05/11/06 - 20060096923 - Method for transferring heterogeneous liquids in microchannels without the occurrence of mixing
In the method for mixing-free transport of homogeneous liquids in microchannels a heterogeneous liquid flow (14) is autonomously divided into portions, transported over a distance and then autonomously recombined. When the flow is divided into portions, individual volumes of a second liquid (16), which may be but must not be ...

04/27/06 - 20060086667 - Methods for the separation of enantiomeric sulfinylacetamides
The present invention is directed to a process for the isolation of the enantiomeric forms of modafinil with high enantiomeric purity and high overall yields by means of a continuous chromatographic process. ...

04/13/06 - 20060076296 - Novel stationary phases for use in high-performance liquid chromatography
silane structure is of form: Where R′ is independently selected from the group consisting of alkenyl, alkynyl, and phenyl, R″ is selected from the group consisting of alkyl, substitute alkyl, alkenyl, substitute alkenyl, alkynyl, and aryl, substitute aryl, R is selected from the group consisting of alkyl, substitute alkyl, alkenyl, ...

04/06/06 - 20060070954 - Methods and systems for protein separation
The present disclosure relates to a system and method for protein separation including: fractionating a mixture of proteins on a reversed-phase superficially porous stationary phase at a temperature of greater than or equal to about 40° C. to recover a protein in from about 70 to 100 weight percent of ...

03/30/06 - 20060065602 - Selective fluoride and ammonia removal by chromatographic separation of wastewater
A process for fluoride removal from wastewater streams produced during industrial operation for further industrial use or to comply with environmental regulations. The process segregates the removal of fluoride and fluorosilicate ions, from the totality of ions in the waste water stream, thus improving treatment efficiency and reducing costs. Ion-exchange ...

03/23/06 - 20060060537 - Method of removing nitric acid from aqueous liquid and method of producing drinks
Disclosed is a method of removing nitric acid from an aqueous liquid containing various components such as vegetable extract, and nitrate ion is removed selectively without spoiling the taste or other components, by subjecting the aqueous liquid to chromatographic treatment with an amphoteric ion exchanger to separate nitrate ion from ...

03/23/06 - 20060060536 - Bed adsorption system
The invention relates to a method of distributing a liquid in the fluid bed of an up-flow or a down-flow fluid bed reactor. The invention provides efficient distribution and a plug flow like fluid flow through the fluid bed where turbulence and/or back-mixing of the fluid are minimised. In accordance ...

03/23/06 - 20060060535 - Flash chromatography cartridge
A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a downstream end of the container and container threads formed on an upstream end of the container. A polymer cap having cap ...

03/23/06 - 20060060534 - Method of preparing a chromatography matrix
The present invention relates to a method of preparing a porous cross-linked polysaccharide chromatography matrix, which comprises to provide an aqueous solution of a gellable polysaccharide, wherein part of the hydroxyl groups are substituted with groups which are not susceptible to nucleophilic attack; to provide essentially spherical droplets of the ...

03/23/06 - 20060060533 - Method of modifying surface of material
The method of the present invention provides various materials such as medical materials having superior biocompatibility and hydrophilicity. ...

03/16/06 - 20060054559 - Organosilanes and substrate bonded with same
The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications. ...

03/16/06 - 20060054558 - Mobile phase treatment for chromatography
A convenient and efficient method for heating or cooling the mobile phase fluid of a chromatographic system prior to its entry into the chromatographic column is described. The “preheating” or “precooling” process is carried out using an apparatus containing a short length of tubing where the mobile phase is heated ...

03/02/06 - 20060043022 - Separating agent for solid-phase extraction
The present invention relates to a separating agent for solid-phase extraction which comprises core particles of a base material; a hydrophilic polymer layer formed on the surface of the particles; and a hydrophobic polymer layer formed on the surface of the hydrophilic polymer layer. The separating agent can be used ...

02/23/06 - 20060037911 - Membrane based volatile component-removal devices for liquid chromatography
In a liquid chromatographic system, removing at least part of a volatile component from the liquid sample stream after separation by flowing it through a volatile component-removal device including a porous wall having a surface coating of a permeable polymer less than 10 μm thick. A liquid chromatographic system suitable ...

02/09/06 - 20060027502 - Chromatographic column seal
A seal on a movable top or bottom plate for use in a chromatography column. The plate is formed of a flow distributor connected to one or more movement rods that control the movement of the top plate within a chromatography column. The plate is formed of two pieces, a ...

02/09/06 - 20060027501 - Method of generating metal chelating affinity ligands
The present invention relates to a method of generating at least one polydentate metal chelating affinity ligand, which method comprises the steps of (a) providing at least one cyclic scaffold comprising a carbonyl, an adjacent sulphur and a nucleophile; (b) providing at least one polydentate metal chelating affinity ligand arm, ...

02/02/06 - 20060021941 - Composite chromatographic sorbent of mineral oxide beads with hydroxyapatite-filled pores
A new adsorbent of a porous mineral oxide material with apatite crystals, preferably hydroxyapatite crystals, in the pores of the mineral oxide material is disclosed. The adsorbent is useful for protein and nucleic acid separations ...

02/02/06 - 20060021940 - Method and device for integrated analysis of a hydrocarbon sample
a) The invention relates to an integrated analysis method and device for characterization of a hydrocarbon sample in distillation fractions. The method carries out a simulated distillation so as to separate the sample into a light fraction and at least one heavy fraction, analyzes the light fraction, collects at least ...

02/02/06 - 20060021939 - Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
Embodiments of the present invention are directed to porous materials for use in solid phase extractions and chromatography. The materials feature at least one hydrophobic component, at least one hydrophilic component and at least one ion-exchange functional group. The materials exhibit superior wetting and ion-exchange performance. ...

01/26/06 - 20060016755 - Capillary loop with a built-in retaining frit
Disclosed herein are an apparatus and method for effectuating increased chromatographic efficiency in a capillary column by employing a retaining frit disposed within an analytical capillary. By disposing the retaining frit within the analytic capillary, the void volume is significantly minimized. The columns and methods described herein produce a simplified ...

01/19/06 - 20060011549 - Solid compositions for selective adsorption from complex mixtures
The present invention relates to a solid and method useful in separating chemical components in a complex mixture when at least one of the chemical components of the mixture is capable of being selectively adsorbed. The solid of the present invention comprises an inorganic substance and moieties (R10) located on ...

01/19/06 - 20060011548 - Mobile phase gradient generation microfluidic device
The present invention relates to a microfluidic device for separating the components of a fluid sample. A cover plate is arranged over the first surface of a substrate, which, in combination with a microchannel formed in the first surface, defines a separation conduit for separating the components of the fluid ...

01/19/06 - 20060011547 - Methods of separating components in treatment fluids
The present invention relates to the separation of components in treatment fluids. More particularly, the present invention relates to the use of a field test that comprises separating components of treatment fluids that have varying molecular weights. In some embodiments, the present invention provides methods of separating components from a ...

12/29/05 - 20050284816 - Method for the analysis of perchlorate
A method for analyzing the content of perchlorate in a sample matrix comprising the steps of extracting the sample matrix and applying it to a reverse phase column, followed by elution with a mobile phase. The reverse phase column optionally has a protein coating deposited thereon. ...

12/08/05 - 20050269267 - Separations platform based upon electroosmosis-driven planar chromatography
The present invention describes a system and method for separation of proteins, peptides and glycans by one-dimensional or two-dimensional electroosmosis-driven planar chromatography. Separation is performed using amphiphilic polymeric membranes, amphiphilic thin-layer chromatography plates or other planar amphiphilic surfaces as the stationary phase with a combination of organic and/or aqueous buffers ...

12/01/05 - 20050263455 - Processing of chemicals in flow-through device with porous media
A method of processing a sample comprising introducing a sample into a flow-through device containing a porous solid media therein, and thereafter subjecting the device to microwave energy. ...

11/17/05 - 20050252859 - Drying spe cartridges
The invention concerns a method for spectrometric investigation of a plurality of samples dissolved in a solvent, comprising the following steps: (a) guiding a first solvent with a sample through an SPE cartridge (5) for concentrating the sample in the cartridge (5); (b) positioning the cartridge (5) in a carrier ...

11/10/05 - 20050247632 - Flash chromatography cartridge
A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a downstream end of the container and container threads formed on an upstream end of the container. A polymer cap having cap ...

11/03/05 - 20050242039 - Deposition of dissolved analyte to hydrophobic surfaces by desolvation of organic solvents
The present invention provides a method of depositing an analyte of interest on a hydrophobic surface, e.g., DIOS-MS substrates, by desolvating organic solvents from the aqueous analyte solution prior to deposition. ...

11/03/05 - 20050242038 - Novel stationary phases for use in high-performance liquid chromatography
where the R groups are independently selected from the group consisting of alkenyl, alkynyl, and phenyl, R′ is selected form the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, aryl, substituted aryl, alkylamine, amide, ether, alcohol, cabamate, ester, an anion exchanger, and a cation exchange. Methods for manufacture and ...

11/03/05 - 20050242037 - Chromatographic two-layer particles
The present invention is a method of producing a chromatographic separation matrix, wherein porous polymeric particles comprised of two layers with different properties are prepared in a two-phase system by (a) providing porous polymeric particles with reactive groups on their surfaces; (b) washing said particles with a first solvent and ...

10/27/05 - 20050236331 - Sr-90/y-90 radionuclide generator for production of high-quality y-90 solution
A process for purifying a stock Sr-90 solution containing stable and radioactive impurities, holding the purified Sr-90 solution for Y-90 ingrowth, and subsequently extracting the Y-90 from the Sr-90NY-90 solution. The stock solution is sequentially passed through two thermoxide-type sorbents (T-3 and T-5), which hold the impurities while passing the ...

10/20/05 - 20050230315 - Protein microarray system
The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of the phosphorylation status of protein samples, including the generation and analysis of protein microarrays. ...

10/13/05 - 20050224415 - Temperature-responsive polymer compound and process for producing the same
A temperature-responsive polymer and polymer material which has ester bond(s) and/or acid amide bond(s) respectively at one or more sites in the side chain and can be arbitrarily controlled by varying the side chain is provided. The process for production thereof and the use thereof are also provided. ...

10/13/05 - 20050224414 - Chromatographic column and methods for controlling sorbent density
Disclosed herein are apparatus and methods for mitigating column bed compression over time. This invention provides for an improved column design and method of controlling bed density in a chromatographic column using a protruding portion of a filter assembly. The invention results in a higher sorbent bed density than can ...

10/06/05 - 20050218078 - Separation of platinum group metals
A process for the chromatographic interseparation of rhodium in admixture with at least one base metal from a feed solution comprising complexes of these metals. The process comprises contacting the solution with at least one chromatographic medium, and eluting one or more fractions such that at least one fraction comprises ...

09/22/05 - 20050205494 - Method for separation of actinide elements
A method for separation of actinide elements comprising feeding a solution containing actinide elements such as americium, curium, californium and the like, into a resin column in which a weakly basic primary, secondary or tertiary anion exchange resin obtained by resinifying pyridine, imidazole or alkylamine has been packed, and then ...

09/22/05 - 20050205493 - Ionic liquids as solvents in headspace gas chromatography
A method of using an ionic liquid as solvent in headspace gas chromatography. ...

09/08/05 - 20050194318 - High throughput autosampler
An auto-injection system provides high throughput screening of fluidic samples. A sample injection valve has a first position which applies a reduced pressure to a sample sipper tube for aspirating a fluidic sample into the sample sipper tube, and a second position which delivers the fluidic sample to a sample ...

09/01/05 - 20050189298 - Chromatography column assembly
Chromatography column assembly of the direct heating type, comprising at least a capillary column, at least a tubular structure which envelops the capillary column and is coaxial with it, means to directly heat the column, means to detect the temperature of the column and one or more electrically insulating covering ...

08/18/05 - 20050178730 - Polar-modified bonded phase materials for chromatographic separations
Novel compositions are disclosed for use as a stationary phase in chromatography comprising an inorganic substrate that is modified with at least one silane having the formula R1δ-Qα-(CH2)βSiR2γX3-γ. In a preferred embodiment, the inorganic substrate is silica gel and is modified with at least two silanes. Methods of preparation and ...

08/11/05 - 20050173346 - Ion exchange particle-bound flow-through porous monolith
A flow-through ion exchange medium comprising a monolithic stationary phase having interconnecting pores defined by pore walls, and fine ion exchange polymeric layering particles irreversibly bound directly or indirectly to the pore walls, and methods of making such medium and its use on chromatographic separators. ...

08/04/05 - 20050167364 - Chromatography methods and chromatography apparatus
Ultrasound transceivers (20) are distributed up the side wall of a chromatography column (1) and enable tracking of the progress of a rising bed front (5) during packing. Comparison with a predetermined stored profile is used for feedback control of the packing pump P. Other uses of ultrasound monitoring of ...

07/28/05 - 20050161402 - Microchip processing method and apparatus
The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment part common to the multiple main flow paths for ...

07/28/05 - 20050161401 - Separation of sugars, sugar alcohols, carbohydrates and mixtures thereof
The present invention relates to a method of separating sugars and sugar alcohols from each other. More particularly the present invention relates to the use of a weakly basic anion exchange resin in a chromatographic separation process. The advantage of the present invention compared with the prior art is that ...

07/21/05 - 20050155933 - Wallless monolith columns for chromatography
A monolith column for chromatography comprising a monolith rod encased with a tubular structure wherein the mass of the interior surface layer of said tubular structure intercalate by an encasing process into the surface layer of said monolith rod through the micro-cavities of said surface layer of said monolith rod, ...

06/23/05 - 20050133452 - Separation method
The present invention relates to a method for separating products from a mixture by reversed phase high performance liquid chromatography using a column packed with a stationary phase which is hydrophobic and a mobile phase, wherein the loading step, during which the products to be separated are introduced in the ...

06/16/05 - 20050127002 - Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
A method that comprises providing a polymerized sol-gel material (PSG) and linking an enzyme to a surface of the PSG via covalent linkage is provided. The surface of the PSG is derivatized with a linker that comprises a functional group for linking itself to the surface of the PSG and ...

06/09/05 - 20050121392 - Chromatographic system with mobile phase recycling ability
A chromatographic system includes a stationary phase, a mobile phase flow line, a detector, a mobile phase supply system, an injection device and a mobile phase switch. A controlling system in data communication with the detector and the mobile phase supply system automatically directs the flow of the mobile phase ...

06/02/05 - 20050115904 - Chromatographic separation method
A method for fractionating a solution into two or more fractions. More particularly the invention relates to a method for fractionating a solution by a chromatographic simulated moving bed (SMB) process in which the dissolved substances present in the feedstock are separated in the partial packed beds, and the formed ...

06/02/05 - 20050115903 - Method and apparatus for extracting nucleic acids from a complex mixture
The invention relates to a method for extracting nucleic acids of microorganisms contained in a complex mixture, particularly a food mixture, comprising at least the following steps: the mixture is clarified; the microorganisms are retained on a filtering cartridge; said microorganisms are lysed; the nucleic acids are recovered, concentrated, and ...



###

FreshPatents.com Support