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Electrophoresis Or Electro-osmosis Processes And Electrolyte Compositions Therefor When Not Provided For Elsewhere

Electrophoresis Or Electro-osmosis Processes And Electrolyte Compositions Therefor When Not Provided For Elsewhere patent applications listed include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.

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Chemistry: Electrical And Wave Energy


Non-distilling Bottoms Treatment > Electrophoresis Or Electro-osmosis Processes And Electrolyte Compositions Therefor When Not Provided For Elsewhere



System and method for electrowetting actuation utilizing diodes
12/18/14 - 20140367258 - An electrowetting system and method for the movement of a droplet across the surface of a substrate, utilizing an applied voltage. The actuation of the droplet is achieved by introducing a diode into the idealized electrical circuit of the electrowetting system. The diode is in parallel with a capacitor (dielectric)...

Droplet manipulation system and method
11/20/14 - 20140339082 - Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one...

Capacitance detection in a droplet actuator
11/13/14 - 20140332380 - A method, circuit and apparatus for detecting capacitance on a droplet actuator, inter alia, for determining the presence, partial presence or absence of a droplet at an electrode on a droplet actuator by: (a) providing a droplet actuator comprising: (i) a substrate comprising electrodes arranged on the substrate for conducting...

Microreactor and method for loading a liquid
10/02/14 - 20140291152 - A microreactor includes: a substrate (2; 102; 202) made of semiconductor material; a plurality of wells (5; 105; 205) separated by walls (6; 106; 206) in the substrate (2; 102; 202); a dielectric structure (7; 107; 207a, 207b) coating at least the top of the walls (6; 106; 206); a...

Method of making a microbead array with attached biomolecules
09/18/14 - 20140262782 - A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relics on the combination of three functional elements: the AC electric field-induced assembly of planar aggregates;...

Water treatment arrangement for steam-assisted oil production operation
09/11/14 - 20140251806 - A water processing arrangement (18) for steam assisted oil production, having a water softening system (30) configured to remove silica from a stream of producer well water (64, 66) using a caustic (70), and an electrodeionization-based water deionization system (36) downstream of the water softening system configured to deionize the...

Droplet actuator and methods
09/11/14 - 20140251807 - A series of microactuators for manipulating small quantities of liquids, and methods of using these for manipulating liquids, are disclosed. The microactuators are based on the phenomenon of electrowetting and contain no moving parts. The force acting on the liquid is a potential-dependent gradient of adhesion energy between the liquid...

Droplet actuator with improved top substrate
08/07/14 - 20140216932 - The invention provides a droplet actuator. The droplet actuator may include a base substrate and a top substrate separated to form a gap. The base substrate may include electrodes configured for conducting droplet operations in the gap; and the top substrate may include a glass substrate portion coupled to a...

Efficient dilution method, including washing method for immunoassay
07/17/14 - 20140197028 - A method of droplet manipulation utilizing a droplet manipulation device includes activating elements of the device to bring a first droplet into proximity of a second droplet, controlling the elements of the device to alter the shape of at least one of the first and second droplets, and further controlling...

Method for controlling substance moving speed and apparatus for controlling the same
07/03/14 - 20140183040 - The present invention provides a method and apparatus for controlling the moving speed of a substance, both of which can adjust the moving speed of a substance to a desired speed. The control method and control apparatus cause a substance to pass through an internal space, in which an electro-osmotic...

Method of electrophoresing nucleic acids, method of concentrating and purifying nucleic acids, cartridge for nucleic acid electrophoresis, and method of producing cartridge for nucleic acid electrophoresis
01/30/14 - 20140027282 - [Solving Means] A method of electrophoresis includes electrophoresing a nucleic acid in which an intercalator having an anionic functional group has been inserted. The method includes mixing a sample containing a nucleic acid, a compound having a functional group which undergoes dehydration condensation reaction with carboxyl groups included in substances...

Method of loading a droplet actuator
01/09/14 - 20140008222 - A method of loading a droplet actuator is provided. In one embodiment, the method may include, providing: a droplet actuator loaded with a filler fluid; a reservoir comprising a droplet fluid; and a fluid path extending from the reservoir into the droplet actuator; and forcing filler fluid from one locus...

Electrorheological fluids incorporated into polymeric articles and tires
12/05/13 - 20130319859 - A polymeric article includes an electrorheological (ER) fluid in a polymer medium. In some applications, the polymer medium forms a body ply of a tire. The ER fluid can be incorporated into the polymeric article in a number of particular ways. The ER fluid may simply fill a pocket in...

Characterization of individual polymer molecules based on monomer-interface interactions
11/28/13 - 20130313112 - The invention relates to a method for characterizing a target polynucleic acid by providing a surface containing a channel of a dimension sufficient to allow sequential monomer-by-monomer passage of a single-stranded polynucleic acid, but not of a double-stranded polynucleic acid; providing a source of hybridized target polynucleic acid at the...

Nanopore-facilitated single molecule detection of nucleic acid
08/29/13 - 20130220809 - The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore sensor with the probe enables sensitive,...

Droplet actuator assemblies and methods of making same
08/15/13 - 20130206597 - The invention provides droplet actuator assemblies and systems and methods of manufacturing the droplet actuator assemblies. In certain embodiments, two-piece enclosures are used to form a droplet actuator assembly that houses a droplet operations substrate. In certain other embodiments, one-piece enclosures are used to form a droplet actuator assembly that...

Manipulating the size of liquid droplets in digital microfluidics
07/11/13 - 20130175169 - Liquid droplet manipulation instrument has electrode array for inducing movement of a droplet by electrowetting, substrate supporting the array and control with electrode selector connected to a voltage control. The selector selects each electrode and provides each with a controlled voltage. The control includes central processing unit for providing the...

Generation of engineered molecular weight standards
06/20/13 - 20130153419 - The invention provides methods of generating physical analog polypeptides, and polypeptides generated employing the methods of the invention, that have the same amino acid composition of a reference protein, but have an unrelated primary sequence. The invention further provides compositions and methods employing such proteins....

Droplet manipulation device
06/13/13 - 20130146455 - Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one...

Cartridge and system for manipulating samples in liquid droplets
05/16/13 - 20130118900 - A cartridge manipulates samples in liquid droplets with an electrode array when a working film is placed on the array. The cartridge has a body with lower surface and wells to hold samples, each with a bottom opening to release liquid. A piercable bottom structure seals the bottom openings. A...

Flow step focusing
03/28/13 - 20130075257 - Flow step focusing isolates and concentrates a molecule of interest by flowing a liquid comprising a molecule of interest through a main channel having an inlet and an outlet with application of a first pressure at the inlet; applying a voltage along the channel during the flowing, wherein the voltage...

Reducing elasto-capillary coalescence of nanostructures with applied electrical fields
03/14/13 - 20130062204 - Various methods and systems are provided for reducing elasto-capillary coalescence of nanostructures. In one embodiment, a method includes providing a plurality of wet nanostructures on an electrode with a counter electrode positioned in air opposite the wet nanostructures. An electric field is applied between the counter electrode and the wet...

Method and apparatus for electrical treatment, and anode used for the same
01/10/13 - 20130008788 - To provide an anode which can prevent scale from being deposited on the contact surface of the anode with materials to be processed, an apparatus including the anode for electrical treatment, and a method for electrical treatment using the apparatus. An endless conveyor belt 1 formed using filter cloth is...

Detecting analytes
11/15/12 - 20120285829 - b) determining the identity and/or quantity of the analyte from EIS data....

Electrowetting mechanism for fluid-application device
11/01/12 - 20120273352 - A fluid-application mechanism is to cause fluid to be applied onto media. An electrowetting mechanism is to generate an electric field to affect the fluid applied onto the media....

Ultrafast sequencing of biological polymers using a labeled nanopore
10/18/12 - 20120261261 - Methods and systems for sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. One or more donor labels, which are attached to a pore or nanopore, may be illuminated or otherwise excited. A polymer having a monomer labeled with one or more acceptor labels, may be translocated...

Quantitative fluorescent protein standards
09/20/12 - 20120234678 - The present invention provides dual labeled protein standards useful for the simultaneous determination of the molecular weight of a subject protein as well as the relative mass (i.e., amount) of the subject protein present in an electrophoresis lane. The invention is also directed to methods suitable for the preparation of...

Biosensor devices, systems and methods therefor
06/07/12 - 20120138460 - A sensing apparatus for sensing target materials including biological or chemical molecules in a fluid. One such apparatus includes a semiconductor-on-insulator (SOI) structure having an electrically-insulating layer, a fluidic channel supported by the SOI structure and configured and arranged to receive and pass a fluid including the target materials, and...

Method for separating nanocarbon material, separation device, and separated nanocarbon dispersion solution
05/03/12 - 20120103809 - A method for separating a nanocarbon material includes a step in which a dispersion solution of the nanocarbon material which is dispersed into nanocarbon micelle groups having a plurality of different electric charges, and a retaining solution having a different specific gravity from the nanocarbon material, are introduced into an...

Metallation enhancements in tumor-imaging and pdt therapy
04/26/12 - 20120097538 - A compound in the form of a metallized tetrpyrollic photosensizer linked to a fluorescent dye where the photosensitizer (PS), is linked by a structure that does not have detrimental radiation emmitance or absorbing characteristics, to a fluorophore, usually a cyanine dye (CD). The photosensitizer in accordance the invention is a...

Fluid delivery manifolds and microfluidic systems
04/12/12 - 20120085644 - Embodiments of fluid distribution manifolds, cartridges, and microfluidic systems are described herein. Fluid distribution manifolds may include an insert member and a manifold base and may define a substantially closed channel within the manifold when the insert member is press-fit into the base. Cartridges described herein may allow for simultaneous...

Msp nanopores and related methods
03/08/12 - 20120055792 - Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins....

Device and method for improving sample injection and stacking
02/23/12 - 20120043206 - The invention provides devices and methods for isolating one or more sample components of a sample material following separation of the sample material into a plurality of sample components. A device includes a separation channel having a sample loading well. A low-conductivity buffer is disposed in the loading well, the...

Selective ion transport device
02/09/12 - 20120031757 - A device for controlled transport of ions comprising a first source element arranged to receive ions of a first class from an ion source, a first target element arranged to release ions of said first class to an ion target, wherein each of said first source element and said first...

Systems and methods for discovery and analysis of markers
12/29/11 - 20110315552 - A business method for use in classifying patient samples. The method includes steps of collecting case samples representing a clinical phenotypic state and control samples representing patients without said clinical phenotypic state. Preferably the system uses a mass spectrometry platform system to identify patterns of polypeptides in said case samples...

Device for crystallizing biopolymer, cell of solution for crystallizing biopolymer, method for controlling alignment of biopolymer, method for crystallizing biopolymer and biopolymer crystal
12/22/11 - 20110308948 - The subject is providing a crystallizing device of a biopolymer, which made to form biopolymer crystal efficiently in crystallization solution of a small amount of biopolymers by applying a low voltage and not to make an electrode disturb but observable a state of crystal formation. As an electrode for applying...

Controlled flow of a thin liquid film by electrowetting
12/15/11 - 20110303541 - Apparatus and methods for controllably wetting a microstructured surface....

System and instrument for processing biological samples and manipulating liquids having biological samples
12/01/11 - 20110290647 - A biological sample processing system comprises a container for large volume processing, a flat polymer film having a lower surface and a hydrophobic upper surface, which is kept at a distance d to the base side of the container by the protrusions. The distance d defines at least one gap...

Microelectrode array architecture
10/13/11 - 20110247934 - Disclosed herein is a device A device of the microelectrode array architecture, comprising: (a) a bottom plate comprising an array of multiple microelectrodes disposed on a top surface of a substrate covered by a dielectric layer; wherein each of the microelectrode is coupled to at least one grounding elements of...

Highly homogeneous molecular markers for electrophoresis
09/22/11 - 20110226620 - The invention relates to marker molecules for identifying physical properties of molecular species separated by the use of electrophoretic systems. The invention further relates to methods for preparing and using marker molecules....

Droplet actuator and methods
09/01/11 - 20110209998 - A series of microactuators for manipulating small quantities of liquids, and methods of using these for manipulating liquids, are disclosed. The microactuators are based on the phenomenon of electrowetting and contain no moving parts. The force acting on the liquid is a potential-dependent gradient of adhesion energy between the liquid...

Process for producing electret coarse powder
08/18/11 - 20110198224 - The process for producing electret coarse powder comprises irradiating a fluorine-containing resin sheet with an electron beam or a radial ray to convert the fluorine-containing resin sheet into an electret sheet, and pulverizing the electret sheet....

Apparatus, compositions and methods for rapid competitive homogeneous assay
07/28/11 - 20110180407 - Embodiments herein concern systems, methods, compositions and apparatus for detection and/or determination of the presence and/or concentration of target molecules in a sample. In certain embodiments, target molecules can be separated and analyzed using non-gel electrophoresis technologies....

Nonoscopic wired-based devices and arrays
07/21/11 - 20110174619 - Electrical devices comprised of nanoscopic wires are described, along with methods of their manufacture and use. The nanoscopic wires can be nanotubes, preferably single-walled carbon nanotubes. They can be arranged in crossbar arrays using chemically patterned surfaces for direction, via chemical vapor deposition. Chemical vapor deposition also can be used...

Ultra high speed and high sensitivity dna sequencing system and method for same
07/21/11 - 20110174620 - The present system relates to a system architecture that uses a single electron transistor (SET) to analyze base sequences of deoxyribonucleic acid (DNA) at ultra high speed in real time. DNA represents the entire body of genetic information and consists of nucleotide units. There are a total of four types...

Integrated bio-analysis and sample preparation system
06/30/11 - 20110155572 - An integrated bio-analysis system incorporates built-in sample preparation capabilities. In one aspect of the present invention, a bio-analysis instrument is provided with a built-in sample preparation device based on PCR (or thermal cycling block/module). In one embodiment of the present invention, a peltier unit in the sample preparation device provides...

Method and device for manipulating and observing liquid droplets
06/23/11 - 20110147215 - A device for manipulating and observing suspended particles in a liquid. The device includes: a first substrate including at least one first orifice forming an inlet site for the liquid, an observation site for observing the suspended particles, and a mechanism displacing the liquid from the inlet site to the...

Nucleic acid marker ladder for estimating mass
06/09/11 - 20110132760 - The invention relates to a nucleic acid marker ladder which is a restriction endonuclease digest, wherein a nucleic acid restriction endonuclease digest is a collection of nucleic acid fragments resulting from complete digestion of one or more nucleic acids by one or more restriction endonucleases; the restriction endonuclease digest contains...

Electrophoresis apparatus and electrophoresis method
05/19/11 - 20110114485 - An electrophoresis apparatus includes a sample separating section for containing a sample separating medium for separating a sample in a horizontal direction, the sample separating section containing the sample separating medium in such a manner that the sample separating medium has an exposed portion at least one end of a...

Blood serum marker for detection and diagnosis of alzheimer's disease
05/05/11 - 20110100816 - The present invention relates to a blood marker for early detection and diagnosis of Alzheimer's disease. More specifically, it relates to an analysis of the protein glycan profile in the blood, and the identification of specific peak ratio's when compared to healthy aged matched subjects that are typical for Alzheimer's...

Primer and probe for detection of mycobacterium intracellulare, and method for detection of mycobacterium intracellulare using the primer or the probe
04/07/11 - 20110079512 - The present invention relates to an oligonucleotide, comprising a part or the entire of the nucleotide sequence shown in any of SEQ ID NO: 1 to SEQ ID NO: 15, or a part or the entire of the sequence complementary to the nucleotide sequence shown in any of SEQ ID...

Ffe media and ffe methods comprising volatile separation media
01/13/11 - 20110005930 - The present invention provides methods and separation media for separating analytes of interest via free flow electrophoresis (FFE) using volatile buffer systems. The separation media provided herein allow a convenient separation of the analytes by electrophoresis, and offer the additional advantage that the buffer compounds and the solvent can be...

Process for producing electret fine particles
01/06/11 - 20110000786 - The method of producing electret fine particles comprises emulsifying a fluorine-containing compound in the liquid phase under atmospheric or elevated pressure in a liquid incompatible with the fluorine-containing compound, to obtain emulsified particles, and irradiating the emulsified particles with an electron ray or a radial ray....

Droplet actuator configurations and methods
12/09/10 - 20100307917 - Droplet actuators for conducting droplet operations, such as droplet transport and droplet dispensing, are provided. In one embodiment, the droplet actuator may include a substrate including, droplet operations electrodes arranged for conducting droplet operations on a surface of the substrate; and reference electrodes associated with the droplet operations electrodes and...

Hemoglobin determination method
11/11/10 - 20100282607 - The present invention provides a method for measuring hemoglobin using electrophoresis, which comprises: immobilizing an ionic polymer on an inner surface of a migration path; and using a buffer solution containing a sulfated polysaccharide....

Droplet actuator with improved top substrate
11/11/10 - 20100282608 - The invention provides a droplet actuator comprising a base substrate and a top substrate separated to form a gap, wherein: (a) the base substrate comprises electrodes configured for conducting droplet operations in the gap; and (b) the top substrate comprises a first portion coupled to second portion, where the second...

Reagent storage and reconstitution for a droplet actuator
11/11/10 - 20100282609 - On-board reagent storage, handling, and dispensing apparatuses and methods for droplet actuator systems are provided. In one embodiment, a fluidic analyzer is provided and includes a droplet actuator including a substrate including a plurality of electrodes configured to actuate a droplet and a reagent storage component in selective fluid communication...

Droplet actuator configurations and methods of conducting droplet operations
10/28/10 - 20100270156 - A droplet actuator with a droplet formation electrode configuration associated with a droplet operations surface, wherein the electrode configuration comprises one or more electrodes configured to control volume of a droplet during formation of a sub-droplet on the droplet operations surface. Methods of making and using the droplet actuator are...

Direct optical interrogation of agents in micro-fluidic channels utilizing whispering gallery resonator approach
09/30/10 - 20100243448 - A whispering gallery mode resonator based optical sensor assembly comprises a flow channel permeable to optical energy and first and second optical waveguides adjacent to a section of the flow channel and adapted to be in first and second evanescent field couplings respectively with the section such that the section...

Devices and methods for analyzing biomolecules and probes bound thereto
09/30/10 - 20100243449 - Devices and methods for sequencing biomolecules include improving signal-to-noise ratio of detection of relative positions of probes hybridized to a biomolecule by coating at least a portion of the biomolecule with a protein prior to its translocation through a structure defining a nanopore, microchannel or nanochannel....

Test chip with plug for measuring the concentration of an analyte in a liquid, housing for test chip and socket for plug
09/23/10 - 20100236926 - Measurement device (10) for taking a liquid sample, comprising: a measurement portion (15) with a measurement surface (20), for being in use contacted with the liquid surface and a plug portion (40) having a plurality of electrical contacts (50), wherein the plug portion (40) is mountable to a socket (110)...

Droplet actuator structures
09/23/10 - 20100236927 - A droplet actuator comprising a substrate comprising an electrode coupled to a voltage source, wherein the droplet actuator is configured such that when voltage is applied to the electrode, an electrostatic energy gradient is established at a surface of the substrate which causes a droplet to be transported in a...

Multiplexed detection schemes for a droplet actuator
09/23/10 - 20100236928 - A droplet actualor having electrodes configured for ejecting droplet operations transporting droplets on a surface, and a sensor arranged in proximity to one or more of the electrodes establishing a detection window on the surface for detection of one or more properties of one or more droplets on the surface,...

Droplet actuators, systems and methods
09/23/10 - 20100236929 - A droplet actuator with arrays of electrodes electrically coupled to a number of controllable voltage sources that is less than the number of electrodes. A method of defining partitions for pin layouts in a droplet actuator for a specific assay, the method including: defining droplet traces for the assay; and...

Transiently bonding drag-tags for separation modalities
08/26/10 - 20100213059 - The invention relates transiently attaching drag-tags to molecules during electrophoresis. The invention includes running buffers having drag-tags that transiently attach to lipophilic moieties attached to the molecules. The lipophilic moieties can be covalently or ionically bonded to the molecules. One particular aspect of the invention is a nucleoside analog or...

Aqueous transfer buffer
08/26/10 - 20100213060 - The present invention relates to an aqueous transfer buffer that provides superior efficiency in transferring polypeptides of a broad range of molecular weight from a matrix used in electrophoresis to another immobilized surface. Also disclosed are electrophoretic methods and devices in which the aqueous transfer solution of this invention is...

Ion mobility analysis of lipoproteins
08/26/10 - 20100213061 - A medical diagnostic method and instrumentation system for analyzing noncovalently bonded agglomerated biological particles is described. The method and system comprises: a method of preparation for the biological particles; an electrospray generator; an alpha particle radiation source; a differential mobility analyzer; a particle counter; and data acquisition and analysis means....

Internal calibration standards for electrophoretic analyses
08/19/10 - 20100206730 - The present teachings relate, among other things, to polynucleotide sequencing, fragment analysis and sample/lane tracking, and to polynucleotide sequencers and analyzers that employ optical detection techniques. Embodiments of the present teachings are described which include, for example, the addition of a calibration standard to a sequencing reaction. Information such as...

Microelectronic device with power lines and signal lines
07/22/10 - 20100181194 - The invention relates to a microelectronic device for manipulating a sample, the device comprising an array of actuator units (AU) and an array of sensitive units (SU). The actuator units (AU) may particularly exert dielectrophoretic forces on a sample (1) in an adjacent sample chamber, and the sensitive units (SU)...

Microfluidic chip for and a method of handling fluidic droplets
07/22/10 - 20100181195 - A micro fluidic chip (100) for handling fluidic droplets (101), the micro fluidic chip (100) comprising a plurality of electrodes (103) being arranged in a Back End of the Line portion (104) of the microfluidic chip (100), and a control unit (106) adapted for controlling electric potentials of the plurality...

Systems and methods for transporting particles
06/17/10 - 20100147686 - Various particle transport systems and components for use in such systems are described. The systems utilize one or more traveling wave grids to selectively transport, distribute, separate, or mix different populations of particles. Numerous systems configured for use in two dimensional and three dimensional particle transport are described....

Systems and methods for transporting particles
06/17/10 - 20100147687 - Various particle transport systems and components for use in such systems are described. The systems utilize one or more traveling wave grids to selectively transport, distribute, separate, or mix different populations of particles. Numerous systems configured for use in two dimensional and three dimensional particle transport are described....